MCID: BSL036
MIFTS: 64

Basal Cell Nevus Syndrome malady

Genetic diseases, Rare diseases, Neuronal diseases, Eye diseases, Skin diseases, Fetal diseases, Cancer diseases, Bone diseases categories

Aliases & Classifications for Basal Cell Nevus Syndrome

About this section
Sources:
49OMIM, 10Disease Ontology, 11diseasecard, 21GeneReviews, 45NIH Rare Diseases, 22GeneTests, 23Genetics Home Reference, 51Orphanet, 65UMLS, 36MeSH, 67UniProtKB/Swiss-Prot, 47Novoseek, 12DISEASES, 24GTR, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 66UMLS via Orphanet, 34MedGen
See all sources

Aliases & Descriptions for Basal Cell Nevus Syndrome:

Name: Basal Cell Nevus Syndrome 49 10 11 21 45 22 23 51 65 36 67
Nevoid Basal Cell Carcinoma Syndrome 10 21 45 22 23 47 12 51
Gorlin Syndrome 10 21 45 22 23 51 24
Nbccs 21 22 23 51
Gorlin-Goltz Syndrome 45 23 51
 
Bcns 21 23 67
Multiple Basal Cell Nevi, Odontogenic Keratocysts, and Skeletal Anomalies 45
Gorlin Syndrome or Gorlin-Goltz Syndrome 67
Naevoid Basal Cell Carcinoma Syndrome 10
Fifth Phacomatosis 45


Classifications:



Characteristics (Orphanet epidemiological data):

51
basal cell nevus syndrome:
Inheritance: Autosomal dominant; Age of onset: Adolescent,Adult,Childhood; Age of death: normal life expectancy


External Ids:

OMIM49 109400
Disease Ontology10 DOID:2512
NCIt42 C2892
Orphanet51 377
ICD10 via Orphanet28 Q87.8
UMLS via Orphanet66 C0004779
MedGen34 C0004779

Summaries for Basal Cell Nevus Syndrome

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NIH Rare Diseases:45 Nevoid basal cell carcinoma syndrome (nbccs) is a condition that increases the risk to develop various cancerous and noncancerous tumors. the most common cancer diagnosed in affected people is basal cell carcinoma, which often develops during adolescence or early adulthood. people with nbccs may also have benign jaw tumors called keratocystic odontogenic tumors. other tumors that may occur include medulloblastomas, and fibromas in the heart or ovaries. additional features in people with nbccs may include skin pits on the hands and feet; large head size (macrocephaly); and/or bone abnormalities of the spine, ribs, or skull. nbccs is inherited in an autosomal dominant manner and is caused by mutations in the ptch1 gene. last updated: 7/16/2014

MalaCards based summary: Basal Cell Nevus Syndrome, also known as nevoid basal cell carcinoma syndrome, is related to basal cell carcinoma 1 and medulloblastoma, and has symptoms including melanocytic nevus, osteolysis and neoplasm of the skin. An important gene associated with Basal Cell Nevus Syndrome is PTCH1 (Patched 1), and among its related pathways are Glypican 3 network and Endochondral Ossification. Affiliated tissues include skin, bone and ovary, and related mouse phenotypes are pigmentation and tumorigenesis.

Genetics Home Reference:23 Gorlin syndrome, also known as nevoid basal cell carcinoma syndrome, is a condition that affects many areas of the body and increases the risk of developing various cancerous and noncancerous tumors.

UniProtKB/Swiss-Prot:67 Basal cell nevus syndrome: An autosomal dominant disease characterized by nevoid basal cell carcinomas and developmental abnormalities such as rib and craniofacial alterations, polydactyly, syndactyly, and spina bifida. In addition, the patients suffer from a multitude of tumors like basal cell carcinomas, fibromas of the ovaries and heart, cysts of the skin, jaws and mesentery, as well as medulloblastomas and meningiomas.

Wikipedia:68 Nevoid basal-cell carcinoma syndrome (NBCCS), also known as basal-cell nevus syndrome, multiple... more...

Description from OMIM:49 109400

GeneReviews summary for bcns

Related Diseases for Basal Cell Nevus Syndrome

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Diseases related to Basal Cell Nevus Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 204)
idRelated DiseaseScoreTop Affiliating Genes
1basal cell carcinoma 130.9PTCH1, PTCH2, SMO
2medulloblastoma30.3GLI1, PTCH1, PTCH2, SHH, SMO, SUFU
3basal cell carcinoma10.9
4meier-gorlin syndrome 110.7
5dysplastic nevus syndrome10.7
6focal dermal hypoplasia10.7
7ectodermal dysplasia10.7
8skin conditions10.7
9skin disease10.7
10solitary bone cyst10.7
11secondary syphilis10.7
12bone cancer10.7
13bone development disease10.7
14dysostosis10.7
15jaw cancer10.7
16x-linked disease10.7
17basal cell carcinoma, multiple10.7
18focal facial dermal dysplasia10.7
19fibroma10.7
20basal cell carcinoma 210.6
21adult syndrome10.6
22skin benign neoplasm10.6
23ovarian fibroma10.6
24child syndrome10.6
25kid syndrome10.6
26meier-gorlin syndrome 310.5
27hypertelorism, microtia, facial clefting syndrome10.5
28basal cell carcinoma 510.5
29epstein syndrome10.5
30skin tag10.5
31breast cancer10.5
32leiomyosarcoma10.5
33meier-gorlin syndrome 210.5
34meier-gorlin syndrome 410.5
35meier-gorlin syndrome 510.5
36lopes gorlin syndrome10.5
37basal cell carcinoma 310.5
38good syndrome10.5
39cell type cancer10.5
40melanoma10.5
41skin melanoma10.5
42wells syndrome10.5
43focal facial dermal dysplasia 310.5
44focal facial dermal dysplasia type i10.5
45oculodentodigital dysplasia10.4
46fanconi anemia, complementation group c10.4
47gillespie syndrome10.4
48edwards syndrome10.4
49phototoxic dermatitis10.4
50facial dermatosis10.4

Graphical network of the top 20 diseases related to Basal Cell Nevus Syndrome:



Diseases related to basal cell nevus syndrome

Symptoms for Basal Cell Nevus Syndrome

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Symptoms by clinical synopsis from OMIM:

109400

Clinical features from OMIM:

109400

Symptoms:

 51 (show all 72)
  • enlargment of jaw/large jaw
  • anomalies of teeth and dentition
  • dermoid sinus/dimple/pit (excluding sacral)
  • chronic skin infection/ulcerations/ulcers/cancrum
  • follicular/erythematous/edematous papules/milium
  • pigmented naevi/naevus pigmentosus/lentigo
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • osteolysis/osteoclasia/bone destruction/erosions
  • bone cyst
  • neoplasms/tumors
  • skin/cutaneous neoplasm/tumor/carcinoma/cancer (excluding melanoma)
  • autosomal dominant inheritance
  • macrocephaly/macrocrania/megalocephaly/megacephaly
  • frontal bossing/prominent forehead
  • broad nasal root
  • hamartoma/tumefaction of the tongue/gingivae/oral mucosa
  • anomalies of the neck
  • scoliosis
  • spina bifida occulta
  • abnormal vertebral size/shape
  • short hand/brachydactyly
  • palmoplantar hyperkeratosis/keratoderma
  • polyposis of the bowel/colon/intestine
  • abnormal/polycystic ovaries
  • skull/cranial anomalies
  • brachycephaly/flat occiput
  • hypertelorism
  • proptosis/exophthalmos
  • prognathism/prognathia
  • anophthalmos/anophthalmia/microphthalmos/microphthalmia
  • glaucoma
  • coloboma of iris
  • cataract/lens opacification
  • coloboma of the optic nerve
  • visual loss/blindness/amblyopia
  • strabismus/squint
  • nystagmus
  • epicanthic folds
  • telecanthus/canthal dystopy
  • anosmia/cacosmia/hypogeusia/hyposmia/olfactory bulb hypoplasia
  • cleft lip and palate
  • enamel anomaly
  • multiple caries
  • anomalies of ear and hearing
  • conductive deafness/hearing loss
  • gynecomastia/breast/mammary gland enlargement/hyperplasia
  • anomalies of the ribs
  • vertebral segmentation anomaly/hemivertebrae
  • long hand/arachnodactyly
  • metacarpal anomalies/archibald's sign
  • syndactyly of fingers/interdigital palm
  • upper limb polydactyly/hexadactyly
  • abnormal pleura/hydrothorax/pleuresia/pleural effusion/chylothorax
  • bronchogenic cyst
  • carotid artery anomalies
  • renal/kidney anomalies
  • renal cyst (single)
  • undescended/ectopic testes/cryptorchidia/unfixed testes
  • late puberty/hypogonadism/hypogenitalism
  • hydrocephaly
  • corpus callosum/septum pellucidum total/partial agenesis
  • chorea/athetosis/choreoathetosis/choreic syndrome
  • seizures/epilepsy/absences/spasms/status epilepticus
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • digestive neoplasm/tumor/carcinoma/cancer
  • heart/cardiac tumor
  • ovary/fallopian tube neoplasm/tumor/carcinoma/cancer (excl. teratoma/germinoma)
  • sarcoma
  • glial tumor/glioblastoma
  • medulloblastoma
  • meningioma
  • tall stature/gigantism/growth acceleration

HPO human phenotypes related to Basal Cell Nevus Syndrome:

(show all 110)
id Description Frequency HPO Source Accession
1 melanocytic nevus hallmark (90%) HP:0000995
2 osteolysis hallmark (90%) HP:0002797
3 neoplasm of the skin hallmark (90%) HP:0008069
4 sacrococcygeal pilonidal abnormality hallmark (90%) HP:0010767
5 bone cyst hallmark (90%) HP:0012062
6 skin ulcer hallmark (90%) HP:0200042
7 polycystic ovaries typical (50%) HP:0000147
8 macrocephaly typical (50%) HP:0000256
9 wide nasal bridge typical (50%) HP:0000431
10 abnormality of the neck typical (50%) HP:0000464
11 palmoplantar keratoderma typical (50%) HP:0000982
12 brachydactyly syndrome typical (50%) HP:0001156
13 frontal bossing typical (50%) HP:0002007
14 scoliosis typical (50%) HP:0002650
15 spina bifida occulta typical (50%) HP:0003298
16 abnormal form of the vertebral bodies typical (50%) HP:0003312
17 intestinal polyposis typical (50%) HP:0200008
18 cryptorchidism occasional (7.5%) HP:0000028
19 tall stature occasional (7.5%) HP:0000098
20 renal cyst occasional (7.5%) HP:0000107
21 oral cleft occasional (7.5%) HP:0000202
22 hydrocephalus occasional (7.5%) HP:0000238
23 epicanthus occasional (7.5%) HP:0000286
24 mandibular prognathia occasional (7.5%) HP:0000303
25 hypertelorism occasional (7.5%) HP:0000316
26 conductive hearing impairment occasional (7.5%) HP:0000405
27 strabismus occasional (7.5%) HP:0000486
28 glaucoma occasional (7.5%) HP:0000501
29 visual impairment occasional (7.5%) HP:0000505
30 telecanthus occasional (7.5%) HP:0000506
31 cataract occasional (7.5%) HP:0000518
32 proptosis occasional (7.5%) HP:0000520
33 optic nerve coloboma occasional (7.5%) HP:0000588
34 iris coloboma occasional (7.5%) HP:0000612
35 nystagmus occasional (7.5%) HP:0000639
36 carious teeth occasional (7.5%) HP:0000670
37 abnormality of dental enamel occasional (7.5%) HP:0000682
38 gynecomastia occasional (7.5%) HP:0000771
39 abnormality of the ribs occasional (7.5%) HP:0000772
40 hand polydactyly occasional (7.5%) HP:0001161
41 abnormality of the metacarpal bones occasional (7.5%) HP:0001163
42 arachnodactyly occasional (7.5%) HP:0001166
43 seizures occasional (7.5%) HP:0001250
44 chorea occasional (7.5%) HP:0002072
45 abnormality of the pleura occasional (7.5%) HP:0002103
46 meningioma occasional (7.5%) HP:0002858
47 medulloblastoma occasional (7.5%) HP:0002885
48 vertebral segmentation defect occasional (7.5%) HP:0003422
49 abnormality of the sense of smell occasional (7.5%) HP:0004408
50 abnormality of the carotid arteries occasional (7.5%) HP:0005344
51 finger syndactyly occasional (7.5%) HP:0006101
52 aplasia/hypoplasia of the corpus callosum occasional (7.5%) HP:0007370
53 aplasia/hypoplasia affecting the eye occasional (7.5%) HP:0008056
54 glioma occasional (7.5%) HP:0009733
55 sarcoma occasional (7.5%) HP:0100242
56 cognitive impairment occasional (7.5%) HP:0100543
57 neoplasm of the heart occasional (7.5%) HP:0100544
58 ovarian neoplasm occasional (7.5%) HP:0100615
59 bronchogenic cyst occasional (7.5%) HP:0100730
60 intellectual disability rare (5%) HP:0001249
61 autosomal dominant inheritance HP:0000006
62 cleft palate HP:0000175
63 cleft upper lip HP:0000204
64 hydrocephalus HP:0000238
65 parietal bossing HP:0000242
66 macrocephaly HP:0000256
67 coarse facial features HP:0000280
68 mandibular prognathia HP:0000303
69 hypertelorism HP:0000316
70 wide nasal bridge HP:0000431
71 strabismus HP:0000486
72 glaucoma HP:0000501
73 cataract HP:0000518
74 microphthalmos HP:0000568
75 iris coloboma HP:0000612
76 abnormality of the sternum HP:0000766
77 short ribs HP:0000773
78 bifid ribs HP:0000892
79 sprengel anomaly HP:0000912
80 milia HP:0001056
81 orbital cyst HP:0001144
82 brachydactyly syndrome HP:0001156
83 motor delay HP:0001270
84 heterogeneous HP:0001425
85 frontal bossing HP:0002007
86 spina bifida HP:0002414
87 scoliosis HP:0002650
88 basal cell carcinoma HP:0002671
89 kyphoscoliosis HP:0002751
90 medulloblastoma HP:0002885
91 hemivertebrae HP:0002937
92 vertebral fusion HP:0002948
93 variable expressivity HP:0003828
94 irregular ossification of hand bones HP:0004280
95 hamartomatous stomach polyps HP:0004795
96 bridged sella turcica HP:0005449
97 calcification of falx cerebri HP:0005462
98 supernumerary ribs HP:0005815
99 vertebral wedging HP:0008422
100 short distal phalanx of the thumb HP:0009650
101 cardiac rhabdomyoma HP:0009729
102 short 4th metacarpal HP:0010044
103 polydactyly HP:0010442
104 odontogenic keratocysts of the jaw HP:0010603
105 skin tags HP:0010609
106 palmar pits HP:0010610
107 plantar pits HP:0010612
108 cardiac fibroma HP:0010617
109 ovarian fibroma HP:0010618
110 down-sloping shoulders HP:0200021

Drugs & Therapeutics for Basal Cell Nevus Syndrome

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Drugs for Basal Cell Nevus Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Imiquimodapproved, investigationalPhase 4, Phase 312699011-02-657469
Synonyms:
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
3M Brand of Imiquimod
4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline
4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
99011-02-6
AC-529
AC1L1N2I
AC1Q4YO9
Aldara
Aldara (TN)
Aldara, Imiquimod
BB_SC-2107
BIDD:GT0859
Beselna
C056493
CHEBI:36704
CHEMBL1282
CID57469
D02500
DB00724
DZ-2636
FT-0080222
HMS2090M14
 
I06-0624
I06-2289
I0747
I5159_SIGMA
IMIQUIMOD
Imiquimod
Imiquimod (JAN/USAN/INN)
Imiquimod [USAN:INN]
Imiquimod acetate
Imiquimodum
LS-178395
MLS000083577
MTD-39
MolPort-002-507-845
NCGC00070736-02
NSC369100
R 837
R-837
S 26308
S-26308
S1211_Selleck
SMR000048307
STK583860
TL8006059
TMX-101
UNII-P1QW714R7M
Vyloma
ZINC19632912
Zartra
Zyclara
2
Vinorelbineapproved, investigationalPhase 333971486-22-160780, 44424639
Synonyms:
5'-Noranhydrovinblastine
71486-22-1
AC1L1KVK
AC1L1TWQ
AC1L75Q4
ANX-530
Ambap71486-22-1
BIDD:PXR0186
C45H54N4O8
CHEBI:480999
CHEMBL607994
CID355119
CID5311497
CID5672
CID60780
CID6426842
D08680
DB00361
Eunades
Exelbine
HMS2090E13
HSDB 7665
I06-0084
I06-0085
KW 2307
KW 2307 base
KW-2307
 
LS-97533
MolPort-006-822-661
MolPort-006-823-869
NCGC00165966-02
NVB
Navelbine
Navelbine (TN)
Navelbine Base
Navelbine base
Nor-5'-anhydrovinblastine
SDP-012
UNII-Q6C979R91Y
Vinorelbin
Vinorelbina
Vinorelbina [Spanish]
Vinorelbine
Vinorelbine (INN)
Vinorelbine Bitartrate
Vinorelbine Ditartarate
Vinorelbine Ditartrate
Vinorelbine Tartrate
Vinorelbine [INN:BAN]
Vinorelbine ditartrate
Vinorelbine tartrate
Vinorelbinum
Vinorelbinum [Latin]
methyl (2b,3b,4b,5a,12b,19a)-4-(acetyloxy)-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-acetoxy-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
vinorelbine
3
GemcitabineapprovedPhase 3180095058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine Hydrochloride
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
4
Capecitabineapproved, investigationalPhase 31179154361-50-960953
Synonyms:
(1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester
154361-50-9
158798-73-3
5'-Deoxy-5-fluoro-N-((pentyloxy)carbonyl)cytidine
5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine
AC1L1U83
AC1Q4KU8
Ambap154361-50-9
C110904
C12650
C15H22FN3O6
CAPE
CAPECITABINE
CHEBI:31348
CHEMBL1773
CID60953
Capecitabin
Capecitabina
Capecitabine
Capecitabine (JAN/USAN/INN)
Capecitabine [USAN]
Capecitabinum
Capecitibine
Capiibine
Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester
Caxeta
 
D01223
DB01101
FT-0082472
HSDB 7656
LS-59070
MolPort-005-938-254
N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine
Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate
Pentyl [1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
R-340
R340
RG-340
Ro 09-1978
Ro 09-1978/000
Ro-09-1978
Ro-09-1978/000
S1156_Selleck
UNII-6804DJ8Z9U
Xabine
Xeloda
Xeloda (TN)
Xeloda, Captabin, Capecitabine
ZINC03806413
capecitabina
capecitabine
capecitabinum
pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate
5
Verteporfinapproved, investigationalPhase 382129497-78-55362420
Synonyms:
Verteporfin
Verteporfina
 
Verteporfinum
Vertéporfine
Visudyne
6
Aminolevulinic acidapprovedPhase 2128106-60-5137
Synonyms:
106-60-5
35BEC718-C970-426A-9859-BF58284C60B4
5-ALA
5-Amino-4-oxo-Pentanoate
5-Amino-4-oxo-Pentanoic acid
5-Amino-4-oxopentanoate
5-Amino-4-oxopentanoic acid
5-Amino-4-oxovalerate
5-Amino-4-oxovaleric acid
5-Amino-Levulinate
5-Amino-Levulinic acid
5-Aminolaevulinate
5-Aminolaevulinic acid
5-Aminolevulinate
5-Aminolevulinate hydrochloride
5-Aminolevulinic acid
5-amino-levulinate
5451-09-2
AC-054
AC1L18K9
AKOS003587520
ALA
ALA-PDT
Aladerm
Amino-levulinic acid
Aminolevulinate
Aminolevulinic
Aminolevulinic acid
BIDD:GT0260
BSPBio_003407
C00430
CCRIS 8958
CHEBI:17549
CHEMBL601
CID137
CPD000857229
 
D07567
DALA
DB00855
DivK1c_006954
EINECS 203-414-1
I14-10101
KBio1_001898
KBio2_002062
KBio2_004630
KBio2_007198
KBio3_002627
KBioGR_001176
KBioSS_002062
Kerastick
LMFA01100055
LS-101793
Levulan Kerastick
Levulinic acid, 5-amino- (8CI)
MLS001333097
MLS001333098
MolPort-001-788-423
NCGC00178086-01
Pentanoic acid, 5-amino-4-oxo- (9CI)
SAM002589919
SMR000857229
SPBio_001843
ST50819610
SpecPlus_000858
Spectrum2_001662
Spectrum3_001654
Spectrum4_000618
Spectrum5_001505
Spectrum_001582
UNII-88755TAZ87
delta-ALA
delta-Aminolevulinate
delta-Aminolevulinic acid
delta-aminolevulinic acid
7
Tazaroteneapproved, investigationalPhase 238118292-40-35381
Synonyms:
118292-40-3
3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-, ethyl ester
3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-,ethyl ester
AC-755
AC1L1K88
AGN 190168
AGN-190168
Avage
Avage (TN)
BIDD:GT0293
C086827
C12531
C21H21NO2S
CHEBI:32184
CHEMBL1657
CID5381
D01132
DB00799
Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
Fabior
I14-1992
 
LS-130838
MolPort-005-932-693
NCGC00167525-01
S1569_Selleck
S1684_Selleck
Suretin
Tazarotene
Tazarotene (JAN/USAN/INN)
Tazarotene [USAN:INN]
Tazaroteno
Tazarotenum
Tazorac
Tazorac, Avage, Zora, Tazarotene
Tazoral
UNII-81BDR9Y8PS
ZINC01542199
Zorac
ethyl 6-(2-(4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate
ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate
tazarotene
tazaroteno
tazarotenum
8
Celecoxibapproved, investigationalPhase 2395169590-42-52662
Synonyms:
169590-42-5
184007-95-2
1oq5
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1Hpyrazol-1-yl] benzenesulfonamide
4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
AC-4228
AC1L1E6K
AI-525
BIDD:GT0408
BRD-K02637541-001-02-4
BSPBio_003596
Benzenesulfonamide,4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)
C07589
C105934
C17H14F3N3O2S
CCRIS 8679
CEL
CEP-33222
CHEBI:41423
CHEMBL118
CID2662
CPD000550473
Celebra
Celebrex
Celebrex (TN)
Celebrex, Celebra, Celecoxib
Celecox
Celecoxi
Celecoxib
Celecoxib (JAN/USAN/INN)
Celecoxib (SC-58635)
Celecoxib [Old RN]
Celecoxib [USAN]
Celecoxibum
Celocoxib
Célécoxib
D00567
DB00482
DivK1c_000893
Eurocox
FT-0080064
HMS1922G14
HMS2089L18
HMS2093I07
HMS502M15
HSDB 7038
I01-1033
IDI1_000893
KBio1_000893
KBio2_000912
 
KBio2_002351
KBio2_003480
KBio2_004919
KBio2_006048
KBio2_007487
KBio3_002830
KBio3_003037
KBioGR_000723
KBioGR_002351
KBioSS_000912
KBioSS_002354
LS-31667
MLS001165684
MLS001195656
MLS001304708
Medicoxib
MolPort-002-885-815
NCGC00091455-01
NCGC00091455-02
NCGC00091455-03
NCGC00091455-04
NCI60_041049
NINDS_000893
NSC719627
Onsenal
P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
Pfizer brand of celecoxib
S1261_Selleck
SAM002589995
SC 58635
SC-58553, SC-58635
SC-58635
SC58635
SMR000550473
SPBio_001512
SPECTRUM1503678
Solexa
Spectrum2_001576
Spectrum3_001996
Spectrum4_000182
Spectrum5_001324
Spectrum_000432
TL8001323
TPI-336
UNM-0000305813
Xilebao
YM 177
YM-177
YM177
ZINC02570895
cMAP_000027
celecoxib
p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
9
Itraconazoleapproved, investigationalPhase 212384625-61-655283
Synonyms:
(+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one
(+/-)-1-[( R *)- sec -butyl]-4-[ p -[4-[ p -[[(2 R *,4 S *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-(DELTA) 2 1,2,4-triazolin-5-one mixture with (+/-)-1-[( R *)- sec -butyl]-4-[ p -[4- [ p -[[(2 S *,4 R *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl] phenyl]-(DELTA) 2 -1,2,4-triazolin-5-one
(1)-cis-4-(4-(4-(4-((2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2,4-dihydro-2-sec-butyl-3H-1,2,4-triazol-3-one
2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)
4-(4-{4-[4-({[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}oxy)phenyl]piperazin-1-yl}phenyl)-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
84604-65-9
84625-61-6
AC-542
AC1L1GQ5
AC1L1IRU
AC1OCEL7
AC1Q6EZ3
AKOS000280875
Ambap84625-61-6
BIDD:GT0796
BRN 6042047
C35H38Cl2N8O4
CHEBI:6076
CHEMBL22587
CHEMBL882
CID3793
CID55283
CID6917738
CID9961741
CPD000058959
Canadiol
D00350
DB01167
EINECS 283-347-2
FT-0082511
HMS2051K14
HMS2090M20
Hyphanox
I01-1043
I0732
ITC
ITCZ
ITZ
Intraconazole
 
Itraconazol
Itraconazol [Spanish]
Itraconazole
Itraconazole & Bovine Lactoferrin
Itraconazole & Nyotran
Itraconazole & Nyotran(Liposomal Nystatin)
Itraconazole (JAN/USAN)
Itraconazole [USAN:BAN:INN:JAN]
Itraconazole oral solution
Itraconazolum
Itraconazolum [Latin]
Itrizole
Itrizole (TN)
Itrizole (tn)
LS-1843
MLS000028582
MLS000759472
MLS000863291
MLS001148245
MolPort-000-883-864
MolPort-003-848-295
NCGC00089812-03
Onmel
Oriconazole
Oriconazole, R51211, Sporanox
Orungal
Prokanazol
R 51211
R-51211
S2476_Selleck
SAM001246679
SMR000058959
Sempera
Spherazole
Sporal
Sporanos
Sporanox
Sporanox (TN)
Sporanox (tn)
Sporonox
TL8005525
Triasporn
UNII-304NUG5GF4
cis-Itraconazole
itraconazole
10
Miconazoleapproved, investigationalPhase 2, Phase 1291222916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
11Cyclooxygenase 2 InhibitorsPhase 2517
12Interferon-gammaPhase 1, Phase 2135
13HydroxyitraconazolePhase 2123
14asparagineNutraceuticalPhase 1, Phase 213
15
Sirolimusapproved, investigationalPhase 1174253123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
16
EverolimusapprovedPhase 11742159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
Afinitor Disperz
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
VOTUBIA
Zortress
everolimus
17
Epinephrineapproved76851-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
18
Lidocaineapproved991137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Afterburn
Akten
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bikini Zone Medicated
Bikini Zone Medicated Creme
Bio-0767
Bio-scriptives Lidum
Bio-scriptives Lidum Hemorroidal (anorectal)
Bio-scriptives Lidum Topical Analgesic
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
Burn Relief Leader
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Comfortcaine
Cuivasil
Curacaine Transdermal Corporation
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
Derma Numb
DermaFlex
Desert Harvest Releveum
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Dr. Numb
Dr. Richs Numbing
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gigi Anesthetic Numbing
Gravocain
H-releve Hemorrhoidal
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
Hawaiian Tropic
Hush Anesthetic
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
LS-805
Lanabiotic
 
Laryng-o-jet
Leostesin
Lida-Mantle
Lidall
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine 4% Cream
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Hydrochloride
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocaine hydrochloride
Lidocainum
Lidocainum [INN-Latin]
Lidocare Mist
Lidocaton
Lidocream 4
Lidocream 5
Lidoderm
Lidoderm 5
Lidoject-1
Lidoject-2
Lifestyles Epic Male Genital Desensitizer
Lignocaine
Lignocainum
Lingocaine
Lmx4
Lmx5
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Numb Master Topical Anesthetic
Numb Nuts
Ocean Potion Instant Burn Relief Ice
Octocaine
Octocaine-100
Octocaine-50
Plum Smooth Plumb Numb Gelee
Premjact Male Desensitizer Pound International
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Recticare
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Simplicity Desensitizing
Simply Numb Endure
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Sole Serum
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Walgreens Aloe Vera Pain Relieving
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocaine-mpf
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zcaine Fast Acting Anesthetic
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
19
Acitretinapproved2955079-83-96437841, 5284513
Synonyms:
(2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid
(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
(all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
(all-e)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
13-cis-Acitretin
44707_FLUKA
44707_SIGMA
54757-46-9
55079-83-9
9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
AC-4702
AC1NR4LJ
AC1Q5T6I
Acetretin
Acitretin
Acitretin (USAN/INN)
Acitretin [USAN:INN:BAN]
Acitretina
Acitretina [Spanish]
Acitretine
Acitretine [French]
Acitretinum
Acitretinum [Latin]
BIDD:GT0617
Bio-0002
CCRIS 5534
CHEBI:50173
CHEMBL1131
CID5284513
CPD000499573
 
D02754
EINECS 259-474-4
Etretin
FT-0082892
HSDB 7187
Isoacitretin
Isoetretin
LS-96920
MLS001076667
MolPort-003-925-892
NCGC00163127-01
NCGC00163127-02
Neotigason
Retinoid etretin
Ro 10-1670
Ro 10-1670/000
Ro 13-7652
Ro-10-1670
Ro-10-1670/000
Ro-13-7652
S1368_Selleck
SAM002589973
SBB064171
SMR000499573
Soriatane
Soriatane (TN)
Soriatane, Acitretin
Spectrum5_002065
TMMP
U0279
UNII-LCH760E9T7
all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid
all-trans-Acitretin
20
Isotretinoinapproved1104759-48-25538, 5282379
Synonyms:
(13-cis)-Retinoate
(13-cis)-Retinoic acid
(13cis)-retinoic acid
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
(2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
(7E,9E,11E,13Z)-retinoic acid
(7e,9e,11e,13Z)-Retinoic acid
13 Cis-Retinoic Acid
13 cis retinoic acid
13-RA
13-cis RA
13-cis retinoic acid
13-cis-Retinoate
13-cis-Retinoic acid
13-cis-Vitamin A acid
13-cis-Vitamin a acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-trans-6-trans-8-trans-nonatetraenoic acid
4-09-00-02388 (Beilstein Handbook Reference)
4759-48-2
97950-17-9
AC-15388
AC1NQZZ4
Absorica
Accutane
Accutane (TN)
Ambap302-79-4
Amnesteem
BML2-E07
BPBio1_000080
BRD-K76723084-001-05-9
BRN 1885770
BSPBio_000072
BSPBio_001331
BSPBio_003345
CCRIS 4286
CHEBI:6067
CHEMBL547
CID5282379
CIP-Isotretinoin
CPD000471891
Claravis
Clarus
D00348
D015474
EINECS 225-296-0
EU-0101081
Epuris
HMS1361C13
HMS1568D14
HMS1791C13
HMS1921D08
HMS1989C13
HMS2092N07
HSDB 3929
IDI1_033801
Isotane
Isotretinoin
Isotretinoin (USP)
 
Isotretinoin Retinoic acid
Isotretinoin Zinc Salt, 13 cis Isomer
Isotretinoin Zinc Salt, 13-cis-Isomer
Isotretinoin [USAN:BAN:INN]
Isotretinoin [USAN:INN:BAN]
Isotretinoina
Isotretinoine
Isotretinoine [INN-French]
Isotretinoino
Isotretinoino [INN-Spanish]
Isotretinoinum
Isotretinoinum [INN-Latin]
Isotrex
LMPR01090021
LS-143465
Lopac0_001081
MLS001074662
MolPort-003-666-394
Myorisan
NCGC00094358-01
NCGC00094358-02
NCGC00094358-03
NCGC00094358-04
NCGC00094358-05
NCGC00094358-06
NCGC00094358-07
NCGC00094358-08
NCGC00094358-09
NCGC00094358-13
Neovitamin A acid
Neovitamin a acid
Prestwick2_000256
Prestwick3_000256
Prestwick_642
R 3255
R3255_SIGMA
Retinoate
Retinoic acid
Ro 4 3780
Ro 4-3780
Ro 43780
Ro-4-3780
Ro-43780
Roaccutan
Roaccutane
Roacutan
SAM002548955
SMR000471891
SPECTRUM1502013
Sotret
Sotret (TN)
Spectrum5_001795
Spectrum5_001937
Teriosal
UNII-EH28UP18IF
Zenatane
cis-RA
cis-Retinoate
cis-Retinoic acid
isotretinoino
21
Folic Acidapproved, nutraceutical285159-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
22Epinephryl borate768
23Racepinephrine768
24Vitamin B Complex2775
25Vitamin B9Nutraceutical2851
26carnitineNutraceutical138
27FolateNutraceutical2851

Interventional clinical trials:

(show all 35)
idNameStatusNCT IDPhase
1Safety and Efficacy Study of Imiquimod 5% Cream Applied 3x Per Week for 8 or 12 Weeks in Low Risk Nodular Basal Cell CarcinomaCompletedNCT00204555Phase 4
2Surgery Versus Combined Treatment With Curettage and Imiquimod for Nodular Basal Cell CarcinomaRecruitingNCT02242929Phase 3
3A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study)RecruitingNCT01945775Phase 3
4Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.TerminatedNCT00049959Phase 3
5To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)CompletedNCT00957229Phase 2
6Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)CompletedNCT01350115Phase 2
7Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the FaceCompletedNCT00489086Phase 2
8Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and BackCompletedNCT00783965Phase 2
9A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome PatientsCompletedNCT00961896Phase 2
10Celecoxib in Preventing Basal Cell Carcinoma in Patients With Basal Cell Nevus SyndromeCompletedNCT00023621Phase 2
11Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell CarcinomasCompletedNCT01556009Phase 2
12Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Nodular Basal Cell CarcinomaCompletedNCT00108121Phase 2
13Photodynamic Therapy Using Blue Light or Red Light in Treating Basal Cell Carcinoma in Patients With Basal Cell Nevus SyndromeRecruitingNCT02258243Phase 2
14Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS)RecruitingNCT02354261Phase 2
15A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell CarcinomaRecruitingNCT02550678Phase 1, Phase 2
16A Study of Two Vismodegib Regimens in Patients With Multiple Basal Cell CarcinomasActive, not recruitingNCT01815840Phase 2
17Non-comparative Trial Exploring Efficacy and Safety of Topical Resiquimod Gel (0.06%) in Patients With Nodular Basal Cell Carcinoma (nBCC)TerminatedNCT01808950Phase 1, Phase 2
18To Evaluate the Safety, Local Tolerability, PK and PD of LDE225 on Sporadic Superficial and Nodular Skin Basal Cell Carcinomas (sBCC)TerminatedNCT01033019Phase 2
19Development of a Nanosecond Pulsed Electric Field System to Treat Skin CancerCompletedNCT01463709Phase 1
20A Phase 1 Study of BMS-833923 (XL139) in Subjects With Advanced or Metastatic CancerCompletedNCT00670189Phase 1
21Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy ParticipantsActive, not recruitingNCT00433485Phase 1
22Photodynamic Therapy and Vismodegib for Multiple Basal Cell CarcinomasNot yet recruitingNCT02639117Phase 1
23Use of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk PatientsCompletedNCT00555633
24The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive DiseasesCompletedNCT00005660
25Isotretinoin in Preventing Skin CancerCompletedNCT00025012
26A Clinical Trial of Dermacorder for Detecting Malignant Skin LesionsCompletedNCT01014819
27Clinical Diagnosis of Basal Cell Carcinoma SubtypeCompletedNCT01370824
28Study of Selected X-linked Disorders: Goltz SyndromeRecruitingNCT00691223
29An Observational Study of the Effectiveness and Safety of Erivedge® in Patients With Advanced Basal Cell CarcinomaRecruitingNCT02371967
30Erismodegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell CarcinomaRecruitingNCT02303041
31Levocarnitine in Treating Patients With Vismodegib-Associated Muscle SpasmsRecruitingNCT01893892
32Study of BMS-833923 in Two Specific Patients With Basal Cell Nevus SyndromeActive, not recruitingNCT02100371
33An Observational Study of Treatment Patterns and Effectiveness and Safety Outcomes in Advanced Basal Cell Carcinoma and Basal Cell Carcinoma Nevus Syndrome Patients(RegiSONIC)Active, not recruitingNCT01604252
34Growth Arrest in Focal Dermal HypoplasiaEnrolling by invitationNCT02463656
35Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus SyndromeNot yet recruitingNCT02157623

Search NIH Clinical Center for Basal Cell Nevus Syndrome


Cochrane evidence based reviews: Basal Cell Nevus Syndrome

Genetic Tests for Basal Cell Nevus Syndrome

About this section

Genetic tests related to Basal Cell Nevus Syndrome:

id Genetic test Affiliating Genes
1 Nevoid Basal Cell Carcinoma Syndrome22 PTCH1, SUFU
2 Gorlin Syndrome24

Anatomical Context for Basal Cell Nevus Syndrome

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MalaCards organs/tissues related to Basal Cell Nevus Syndrome:

33
Skin, Bone, Ovary, Heart, Eye, Testes, Tongue

Animal Models for Basal Cell Nevus Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Basal Cell Nevus Syndrome:

38 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.2BMPR1A, GAS1, GLI3, PTCH1, SUFU
2MP:00020068.9BMPR1A, GLI1, PTCH1, PTCH2, SHH, SUFU
3MP:00107718.4BMPR1A, GLI2, GLI3, PTCH1, PTCH2, SHH
4MP:00053778.3BMPR1A, GAS1, GLI2, GLI3, ROR2, SHH
5MP:00028738.2BMPR1A, GLI1, GLI2, PTCH1, PTCH2, SHH
6MP:00053698.2BMPR1A, GLI2, KIF7, PTCH1, PTCH2, SHH
7MP:00030127.7BMPR1A, GLI1, GLI2, GLI3, KIF7, PTCH1
8MP:00053917.3BMPR1A, GAS1, GLI2, GLI3, KIF7, PTCH1
9MP:00053787.3BMPR1A, GAS1, GLI1, GLI2, GLI3, PTCH1
10MP:00053857.2BMPR1A, GAS1, GLI3, KIF7, PTCH1, PTCH2
11MP:00053907.2BMPR1A, GAS1, GLI2, GLI3, KIF7, PTCH1
12MP:00053827.2BMPR1A, GAS1, GLI2, GLI3, KIF7, PTCH1
13MP:00053797.0BMPR1A, DHH, GLI1, GLI2, GLI3, PTCH1
14MP:00053717.0BMPR1A, GAS1, GLI1, GLI2, GLI3, KIF7
15MP:00053847.0BMPR1A, GAS1, GLI1, GLI2, GLI3, KIF7
16MP:00053887.0BMPR1A, GAS1, GLI1, GLI2, GLI3, KIF7
17MP:00053816.9DHH, GLI1, GLI2, GLI3, KIF7, PTCH1
18MP:00053806.7BMPR1A, GAS1, GLI1, GLI2, GLI3, KIF7
19MP:00107686.7BMPR1A, GAS1, GLI1, GLI2, GLI3, KIF7
20MP:00053896.4BMPR1A, DHH, GLI1, GLI2, GLI3, KIF7
21MP:00036315.9BMPR1A, DHH, GAS1, GLI1, GLI2, GLI3
22MP:00053765.8BMPR1A, DHH, GAS1, GLI2, GLI3, KIF7

Publications for Basal Cell Nevus Syndrome

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Articles related to Basal Cell Nevus Syndrome:

(show all 47)
idTitleAuthorsYear
1
Dermoscopy for Identification of Basal Cell Carcinomas in Basal Cell Nevus Syndrome During Carbon Dioxide Laser Surgery. (26572667)
2015
2
Basal Cell Nevus Syndrome: An Update on Genetics and Treatment. (26409035)
2015
3
Hedgehog Pathway Inhibition for Locally Advanced Periocular Basal Cell Carcinoma and Basal Cell Nevus Syndrome. (25935097)
2015
4
Basal cell nevus syndrome: clinical and molecular review and case report. (26356331)
2015
5
Basal cell nevus syndrome or Gorlin syndrome. (26564075)
2015
6
Intermittent Vismodegib Therapy in Basal Cell Nevus Syndrome. (26509945)
2015
7
Sonic hedgehog signaling in Basal cell nevus syndrome. (25172843)
2014
8
Axillary basal cell carcinoma in patients with Goltz-Gorlin syndrome: report of basal cell carcinoma in both axilla of a woman with basal cell nevus syndrome and literature review. (25148279)
2014
9
The use of vismodegib to shrink keratocystic odontogenic tumors in patients with basal cell nevus syndrome. (24623282)
2014
10
Tazarotene: randomized, double-blind, vehicle-controlled, and open-label concurrent trials for basal cell carcinoma prevention and therapy in patients with basal cell nevus syndrome. (24441673)
2014
11
Squamous cell carcinoma of the maxilla in a patient with basal cell nevus syndrome. (24621716)
2014
12
Comment on basal cell carcinoma rebound after cessation of vismodegib in an individual with basal cell nevus syndrome. (23682843)
2013
13
Meningeal calcification in basal cell nevus syndrome. (24287476)
2013
14
"PTCH"-ing it together: a basal cell nevus syndrome review. (23725561)
2013
15
The Ptch1(DL) mouse: a new model to study lambdoid craniosynostosis and basal cell nevus syndrome-associated skeletal defects. (23897749)
2013
16
Retraction: Basal cell nevus syndrome showing several histologic types of basal cell carcinoma. (22577287)
2012
17
Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome. (22670904)
2012
18
Basal cell nevus syndrome: a rare entity. (22960843)
2012
19
Long-term safety, tolerability, and efficacy of vismodegib in two patients with metastatic basal cell carcinoma and basal cell nevus syndrome. (25386306)
2011
20
Conjunctival ganglioglioma as a feature of basal cell nevus syndrome. (21907124)
2011
21
A novel phenotype with features of basal cell nevus syndrome and basaloid follicular hamartoma syndrome. (21679799)
2011
22
Basal cell nevus syndrome showing several histologic types of Basal cell carcinoma. (22028568)
2011
23
Infundibulocystic basal cell carcinoma of the eyelid in basal cell nevus syndrome. (20489535)
2010
24
Germline PTCH1 mutations in Japanese basal cell nevus syndrome patients. (19557015)
2009
25
Recurrent petrous apex cholesteatoma in a patient with basal cell nevus syndrome. (18722240)
2008
26
Patched homologue 1 mutations in four Japanese families with basal cell nevus syndrome. (17021131)
2006
27
Identification of genetic loci for basal cell nevus syndrome and inflammatory bowel disease in a single large pedigree. (16733713)
2006
28
Review of patients with basal cell nevus syndrome. (16855496)
2006
29
Delineation of an interstitial 9q22 deletion in basal cell nevus syndrome. (15690381)
2005
30
Meningiomas after medulloblastoma irradiation treatment in a patient with basal cell nevus syndrome. (16227103)
2005
31
Basal cell nevus syndrome. (15725922)
2005
32
A plea for the analysis of Vitamin-D levels in patients under photoprotection, including patients with xeroderma pigmentosum (XP) and basal cell nevus syndrome (BCNS). (15088627)
2004
33
Interstitial deletion of chromosome 9, int del(9)(9q22.31-q31.2), including the genes causing multiple basal cell nevus syndrome and Robinow/brachydactyly 1 syndrome. (12548386)
2003
34
Ultrapulse CO2 used for the successful treatment of basal cell carcinomas found in patients with basal cell nevus syndrome. (11896785)
2002
35
Novel mutations in the PATCHED gene in basal cell nevus syndrome. (12175781)
2002
36
A mouse model for medulloblastoma and basal cell nevus syndrome. (11718263)
2001
37
A novel polymorphism in the PTC gene allows easy identification of allelic loss in basal cell nevus syndrome lesions. (11277394)
2001
38
Allelic loss at the PTCH gene locus in jaw cysts but not in palmar pits in patients with basal cell nevus syndrome. (11000293)
2000
39
Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome. (9620294)
1998
40
Repair of directly and indirectly UV-induced DNA lesions and of DNA double-strand breaks in cells from skin cancer-prone patients with the disorders dysplastic nevus syndrome or basal cell nevus syndrome. (8912431)
1997
41
The occurrence of endometrial adenocarcinoma in a patient with basal cell nevus syndrome. (9264223)
1997
42
Human homolog of patched, a candidate gene for the basal cell nevus syndrome. (8658145)
1996
43
Basal cell nevus syndrome and dysplastic nevus syndrome: investigation of gene expression by differential hybridization. (8818188)
1996
44
Basal cell nevus syndrome and medulloblastoma: a case report. (8060441)
1993
45
Hypersensitivity of skin fibroblasts from basal cell nevus syndrome patients to killing by ultraviolet B but not by ultraviolet C radiation. (2297704)
1990
46
Nevoid basal cell carcinoma syndrome. A review and case report of a patient with unilateral basal cell nevus syndrome. (3537024)
1986
47
Concurrence of features of pseudohypoparathyroidism, pseudopseudohypoparathyroidism and basal-cell nevus syndrome. (5480625)
1970

Variations for Basal Cell Nevus Syndrome

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UniProtKB/Swiss-Prot genetic disease variations for Basal Cell Nevus Syndrome:

67
id Symbol AA change Variation ID SNP ID
1PTCH1p.Leu175ProVAR_007843
2PTCH1p.Phe376SerVAR_007844
3PTCH1p.Arg1114TrpVAR_007847
4PTCH1p.Gly509ValVAR_010975
5PTCH1p.Asp513TyrVAR_010976
6PTCH1p.Gly1069ArgVAR_010979
7PTCH1p.Ser1132ProVAR_010980
8PTCH1p.Ser1132TyrVAR_010981
9PTCH1p.Glu1438AspVAR_010984
10PTCH1p.Thr230ProVAR_020845

Clinvar genetic disease variations for Basal Cell Nevus Syndrome:

5 (show all 25)
id Gene Variation Type Significance SNP ID Assembly Location
1PTCH1NM_000264.3(PTCH1): c.3168+2T> Csingle nucleotide variantPathogenicrs786204056GRCh37Chr 9, 98220293: 98220293
2PTCH1NM_000264.3(PTCH1): c.343G> T (p.Gly115Ter)single nucleotide variantPathogenicrs794727242GRCh37Chr 9, 98268740: 98268740
3PTCH1NM_000264.3(PTCH1): c.3449+1G> Asingle nucleotide variantLikely pathogenicGRCh38Chr 9, 95453477: 95453477
4PTCH1NM_000264.3(PTCH1): c.3450-2A> Gsingle nucleotide variantLikely pathogenicGRCh37Chr 9, 98212224: 98212224
5PTCH1NM_000264.3(PTCH1): c.945+1G> Asingle nucleotide variantLikely pathogenicGRCh38Chr 9, 95480389: 95480389
6PTCH1NM_000264.3(PTCH1): c.2799delG (p.Tyr934Metfs)deletionPathogenicGRCh38Chr 9, 95459688: 95459688
7PTCH1NM_000264.3(PTCH1): c.2842_2849delTGGGTCCA (p.Trp948Argfs)deletionPathogenicGRCh38Chr 9, 95459638: 95459645
8PTCH1NM_000264.3(PTCH1): c.612C> G (p.Tyr204Ter)single nucleotide variantPathogenicGRCh38Chr 9, 95482176: 95482176
9PTCH1NM_000264.3(PTCH1): c.666T> A (p.Tyr222Ter)single nucleotide variantPathogenicGRCh38Chr 9, 95482029: 95482029
10PTCH1NM_000264.3(PTCH1): c.1502A> G (p.Gln501Arg)single nucleotide variantPathogenicGRCh38Chr 9, 95477548: 95477548
11PTCH1NM_000264.3(PTCH1): c.1591_1601delATCCCTTTTGA (p.Ile531Glyfs)deletionPathogenicGRCh38Chr 9, 95476760: 95476770
12PTCH1GRCh37/hg19 9q22.32(chr9: 98207091-98210940)x1copy number lossPathogenicGRCh37Chr 9, 98207091: 98210940
13more than 10GRCh37/hg19 9q22.32(97579146-99280739)x1copy number lossPathogenicGRCh37Chr 9, 97579146: 99280739
14SUFUNM_016169.3(SUFU): c.1022+1G> Asingle nucleotide variantPathogenicrs587776578GRCh37Chr 10, 104359302: 104359302
15PTCH1PTCH1, TRP129TERsingle nucleotide variantPathogenic
16PTCH2NM_001166292.1(PTCH2): c.2156G> A (p.Arg719Gln)single nucleotide variantPathogenicrs121434397GRCh37Chr 1, 45293289: 45293289
17PTCH1PTCH1, 9-BP INS, CODON 815, PRO-ASN-ILE INSinsertionPathogenic
18PTCH1PTCH1, 11-BP DEL, NT2442deletionPathogenic
19PTCH1NM_000264.3(PTCH1): c.1081C> T (p.Gln361Ter)single nucleotide variantPathogenicrs199476090GRCh37Chr 9, 98241416: 98241416
20PTCH1PTCH1, 37-BP DEL, NT808deletionPathogenic
21PTCH1PTCH1, 1148G-Asingle nucleotide variantPathogenic
22PTCH1PTCH1, 2-BP INS, 2047CTinsertionPathogenic
23PTCH1PTCH1, 1-BP INS, 2000CinsertionPathogenic
24PTCH1PTCH1, 1-BP DEL, 2583CdeletionPathogenic
25PTCH1PTCH1, 1-BP INS, 1247TinsertionPathogenic

Cosmic variations for Basal Cell Nevus Syndrome:

7 (show top 50)    (show all 122)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
145015TP53skin,NS,carcinoma,basal cell carcinoma3
210887TP53skin,face,carcinoma,basal cell carcinoma3
310771TP53skin,NS,carcinoma,basal cell carcinoma3
443665TP53skin,NS,carcinoma,basal cell carcinoma3
544167TP53skin,NS,carcinoma,basal cell carcinoma3
644310TP53skin,NS,carcinoma,basal cell carcinoma3
744925TP53skin,NS,carcinoma,basal cell carcinoma3
843702TP53skin,NS,carcinoma,basal cell carcinoma3
944071TP53skin,NS,carcinoma,basal cell carcinoma3
1011084TP53skin,face,carcinoma,basal cell carcinoma3
116549TP53skin,NS,carcinoma,basal cell carcinoma3
1210726TP53skin,face,carcinoma,basal cell carcinoma3
1343585TP53skin,face,carcinoma,basal cell carcinoma3
1444552TP53skin,face,carcinoma,basal cell carcinoma3
1543577TP53skin,NS,carcinoma,basal cell carcinoma3
1644227TP53skin,face,carcinoma,basal cell carcinoma3
1743842TP53skin,NS,carcinoma,basal cell carcinoma3
1810660TP53skin,NS,carcinoma,basal cell carcinoma3
1944096TP53skin,NS,carcinoma,basal cell carcinoma3
2044074TP53skin,NS,carcinoma,basal cell carcinoma3
2143583TP53skin,eye,carcinoma,basal cell carcinoma3
2245020TP53skin,face,carcinoma,basal cell carcinoma3
2345019TP53skin,face,carcinoma,basal cell carcinoma3
2443608TP53skin,NS,carcinoma,basal cell carcinoma3
2544606TP53skin,NS,carcinoma,basal cell carcinoma3
2643616TP53skin,NS,carcinoma,basal cell carcinoma3
2743635TP53skin,NS,carcinoma,basal cell carcinoma3
2844909TP53skin,face,carcinoma,basal cell carcinoma3
2945740TP53skin,NS,carcinoma,basal cell carcinoma3
3010648TP53skin,NS,carcinoma,basal cell carcinoma3
3143742TP53skin,face,carcinoma,basal cell carcinoma3
3243592TP53skin,NS,carcinoma,basal cell carcinoma3
3310992TP53skin,face,carcinoma,basal cell carcinoma3
3410728TP53skin,face,carcinoma,basal cell carcinoma3
3545017TP53skin,face,carcinoma,basal cell carcinoma3
3610768TP53skin,face,carcinoma,basal cell carcinoma3
3744126TP53skin,eye,carcinoma,basal cell carcinoma3
3843920TP53skin,face,carcinoma,basal cell carcinoma3
3944226TP53skin,NS,carcinoma,basal cell carcinoma3
4045776TP53skin,face,carcinoma,basal cell carcinoma3
4144068TP53skin,face,carcinoma,basal cell carcinoma3
4243581TP53skin,NS,carcinoma,basal cell carcinoma3
4345420TP53skin,NS,carcinoma,basal cell carcinoma3
4410656TP53skin,NS,carcinoma,basal cell carcinoma3
4510659TP53skin,NS,carcinoma,basal cell carcinoma3
4643582TP53skin,NS,carcinoma,basal cell carcinoma3
4743584TP53skin,NS,carcinoma,basal cell carcinoma3
4845739TP53skin,NS,carcinoma,basal cell carcinoma3
4944603TP53skin,NS,carcinoma,basal cell carcinoma3
506932TP53skin,NS,carcinoma,basal cell carcinoma3

Expression for genes affiliated with Basal Cell Nevus Syndrome

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Search GEO for disease gene expression data for Basal Cell Nevus Syndrome.

Pathways for genes affiliated with Basal Cell Nevus Syndrome

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Pathways related to Basal Cell Nevus Syndrome according to GeneCards Suite gene sharing:

(show all 15)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9PTCH1, SHH
29.2BMPR1A, GLI3, PTCH1
3
Show member pathways
8.8DHH, PTCH1, PTCH2, SHH, SMO
48.8GLI1, GLI2, PTCH1, SHH, SMO
58.6GLI1, GLI2, PTCH1, PTCH2, SHH, SUFU
6
Show member pathways
8.1DHH, GAS1, GLI2, PTCH1, PTCH2, SHH
78.0GLI1, GLI2, GLI3, PTCH1, SHH, SMO
8
Show member pathways
8.0DHH, GAS1, GLI1, PTCH1, PTCH2, ROR2
97.7GLI1, GLI2, GLI3, PTCH1, PTCH2, SHH
10
Show member pathways
7.6DHH, GLI1, GLI2, GLI3, PTCH1, PTCH2
11
Show member pathways
7.4BMPR1A, DHH, GAS1, GLI1, PTCH1, PTCH2
12
Show member pathways
7.0DHH, GAS1, GLI1, GLI2, GLI3, PTCH1
13
Show member pathways
7.0DHH, GAS1, GLI1, GLI2, GLI3, PTCH1
14
Show member pathways
6.6DHH, GAS1, GLI1, GLI2, GLI3, KIF7
15
Show member pathways
5.6BMPR1A, DHH, GAS1, GLI1, GLI2, GLI3

GO Terms for genes affiliated with Basal Cell Nevus Syndrome

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Cellular components related to Basal Cell Nevus Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1caveolaGO:00059019.6BMPR1A, PTCH1, SMO
2ciliary baseGO:00975469.4GLI1, GLI2, GLI3, SUFU
3axonemeGO:00059309.2GLI1, GLI2, GLI3
4primary ciliumGO:00723728.9GLI1, GLI2, GLI3, PTCH1, SMO
5ciliary tipGO:00975428.3GLI1, GLI2, GLI3, KIF7, SMO, SUFU
6ciliumGO:00059298.2GLI1, GLI2, GLI3, KIF7, SMO

Biological processes related to Basal Cell Nevus Syndrome according to GeneCards Suite gene sharing:

(show top 50)    (show all 80)
idNameGO IDScoreTop Affiliating Genes
1epidermal cell fate specificationGO:000995710.6PTCH1, PTCH2
2determination of left/right asymmetry in lateral mesodermGO:000314010.5SHH, SMO
3positive regulation of hh target transcription factor activityGO:000722810.4SHH, SMO
4notochord regressionGO:006003210.4GLI1, GLI2
5cell differentiation involved in kidney developmentGO:006100510.4GLI3, PTCH1
6negative regulation of alpha-beta T cell differentiationGO:004663910.3GLI3, SHH
7epithelial-mesenchymal cell signalingGO:006068410.3SHH, SMO
8spinal cord dorsal/ventral patterningGO:002151310.2GLI2, GLI3
9smoothened signaling pathway involved in ventral spinal cord interneuron specificationGO:002177510.2GLI2, GLI3
10smoothened signaling pathway involved in spinal cord motor neuron cell fate specificationGO:002177610.2GLI2, GLI3
11tube developmentGO:003529510.2GLI2, GLI3
12renal system developmentGO:007200110.2PTCH1, SHH, SMO
13somite developmentGO:006105310.1PTCH1, SHH, SMO
14ventral midline developmentGO:000741810.1GLI1, GLI2, SHH
15cerebellar cortex morphogenesisGO:002169610.0GLI1, GLI2, SMO
16smoothened signaling pathway involved in dorsal/ventral neural tube patterningGO:006083110.0GLI2, GLI3, PTCH1
17hindgut morphogenesisGO:00074429.9GLI2, GLI3, SHH
18positive regulation of mesenchymal cell proliferationGO:00020539.9BMPR1A, SHH, SMO
19positive regulation of neuroblast proliferationGO:00020529.9GLI3, SHH, SMO
20mammary gland developmentGO:00308799.8GLI2, GLI3, PTCH1
21branching involved in ureteric bud morphogenesisGO:00016589.8GLI3, PTCH1, SHH
22dorsal/ventral neural tube patterningGO:00219049.8GLI2, PTCH1, SHH, SMO
23anatomical structure developmentGO:00488569.8GLI2, GLI3, SHH
24positive regulation of protein import into nucleusGO:00423079.8GLI3, SHH, SMO
25anatomical structure formation involved in morphogenesisGO:00486469.7GLI2, GLI3, SHH
26branching morphogenesis of an epithelial tubeGO:00487549.7GLI2, GLI3, SHH
27embryonic limb morphogenesisGO:00303269.7GLI3, PTCH1, SHH
28smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferationGO:00219389.7GLI1, GLI2, SHH, SMO
29embryonic morphogenesisGO:00485989.7BMPR1A, GLI3, SHH
30regulation of smoothened signaling pathwayGO:00085899.7GAS1, GLI1, GLI2, PTCH1
31pituitary gland developmentGO:00219839.7BMPR1A, GLI1, GLI2
32embryonic organ developmentGO:00485689.6BMPR1A, PTCH1, SHH, SMO
33proximal/distal pattern formationGO:00099549.5GLI1, GLI2, GLI3
34spinal cord motor neuron differentiationGO:00215229.4GLI2, GLI3, PTCH1, SHH
35positive regulation of smoothened signaling pathwayGO:00458809.4GLI1, KIF7, SHH, SMO
36heart morphogenesisGO:00030079.3BMPR1A, PTCH1, SMO
37negative regulation of canonical Wnt signaling pathwayGO:00900909.2GLI1, GLI3, ROR2, SHH
38anterior/posterior pattern specificationGO:00099529.2BMPR1A, GLI3, SHH, SMO
39negative regulation of smoothened signaling pathwayGO:00458799.1GLI3, KIF7, PTCH1, PTCH2, SUFU
40embryonic digit morphogenesisGO:00427338.9BMPR1A, GLI2, GLI3, ROR2, SHH
41in utero embryonic developmentGO:00017018.8BMPR1A, GLI2, GLI3, PTCH1, SMO
42odontogenesis of dentin-containing toothGO:00424758.6BMPR1A, GLI2, GLI3, SHH, SMO
43pattern specification processGO:00073898.6BMPR1A, GLI2, GLI3, PTCH1, SHH, SMO
44lung developmentGO:00303248.5BMPR1A, GLI1, GLI2, GLI3, SHH
45developmental growthGO:00485898.5BMPR1A, GAS1, GLI2, GLI3, SHH, SMO
46heart developmentGO:00075078.4BMPR1A, GLI2, GLI3, SHH
47negative regulation of transcription from RNA polymerase II promoterGO:00001228.4GLI2, GLI3, PTCH1, SHH, SMO, SUFU
48dorsal/ventral pattern formationGO:00099538.3BMPR1A, GLI1, GLI2, GLI3, PTCH1, SHH
49smoothened signaling pathwayGO:00072247.9GLI1, GLI2, GLI3, KIF7, PTCH1, ROR2
50positive regulation of transcription, DNA-templatedGO:00458937.7BMPR1A, GLI1, GLI2, GLI3, PTCH1, ROR2

Molecular functions related to Basal Cell Nevus Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1smoothened bindingGO:000511910.1PTCH1, PTCH2
2hedgehog family protein bindingGO:009710810.1PTCH1, PTCH2
3Wnt-protein bindingGO:00171479.8ROR2, SMO
4hedgehog receptor activityGO:00081589.7PTCH1, PTCH2
5patched bindingGO:00051139.3DHH, PTCH1, SHH, SMO

Sources for Basal Cell Nevus Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet