MCID: BSL004
MIFTS: 31

Basilar Artery Occlusion malady

Cardiovascular diseases category

Aliases & Classifications for Basilar Artery Occlusion

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Aliases & Descriptions for Basilar Artery Occlusion:

Name: Basilar Artery Occlusion 10 12


Classifications:



External Ids:

Disease Ontology10 DOID:13446
ICD9CM29 433.0

Summaries for Basilar Artery Occlusion

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MalaCards based summary: Basilar Artery Occlusion is related to stroke, ischemic and cerebritis. An important gene associated with Basilar Artery Occlusion is PLAT (Plasminogen Activator, Tissue), and among its related pathways are A-beta Plaque Formation and APP Metabolism and Dissolution of Fibrin Clot. Affiliated tissues include brain, and related mouse phenotypes are respiratory system and hematopoietic system.

Related Diseases for Basilar Artery Occlusion

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Diseases related to Basilar Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1stroke, ischemic30.4F2, PLAT, PLG, TSPAN33
2cerebritis10.5
3ischemia10.5
4aneurysm10.5
5myocardial infarction10.4
6acute myocardial infarction10.4
7mutism10.4
8cervicitis10.4
9pontine hemorrhage10.4
10relapsing polychondritis10.2F2, PLG
11irritable bowel syndrome10.2F2, PLG
12cervical alveolar soft part sarcoma10.2F2, PLG
13greenberg skeletal dysplasia10.2
14coronary heart disease 510.2
15coronary heart disease 810.2
16hemorrhage, intracerebral10.2
17duchenne muscular dystrophy10.2
18peripheral vascular disease10.2
19brain ischemia10.2
20burns10.2
21cerebral hemorrhage10.2
22hydrocephalus10.2
23bulimia nervosa10.2
24choroiditis10.2
25cerebral artery occlusion10.2
26mitral valve insufficiency10.2
27vertebral artery occlusion10.2
28arteriovenous malformation10.2
29locked-in syndrome10.2
30cortical blindness10.2
31akinetic mutism10.2
32central nervous system vasculitis10.2
33cerebral arterial disease10.2
34cerebrovascular disease10.2
35meningitis10.2
36muscular dystrophy10.2
37syphilis10.2
38vasculitis10.2
39encephalopathy10.2
40headache10.2
41ocular hypotension10.2ITGA2B, PLAT
42equatorial staphyloma10.2F2, ITGA2B
43abducens nerve neoplasm10.2F2, PLG
44adult acute lymphocytic leukemia10.2ITGA2B, PLAT, PLG
45thrombophilia due to activated protein c resistance10.2F2, PLAT, PLG
46dissociative disorder10.2F2, PLAT, PLG
47blood group incompatibility10.2F2, ITGA2B, PLG
48lambert-eaton myasthenic syndrome10.2F2, PLG
49cerebrum cancer10.1F2, ITGA2B, PLAT
50thymic carcinoma10.1F2, PLAT

Graphical network of the top 20 diseases related to Basilar Artery Occlusion:



Diseases related to basilar artery occlusion

Symptoms for Basilar Artery Occlusion

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Drugs & Therapeutics for Basilar Artery Occlusion

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Drugs for Basilar Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TiclopidineapprovedPhase 418555142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
2
CilostazolapprovedPhase 49873963-72-12754
Synonyms:
3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
3,4-dihydro-6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one
6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
73963-72-1
89332-50-3
AC-4334
AC1L1EE2
BRD-K67017579-001-04-2
BRD-K67017579-001-05-9
BRD-K67017579-001-07-5
BRD-K67017579-001-13-3
BRN 3632107
BSPBio_002759
C 0737
C045645
C0737_SIGMA
C20H27N5O2
CHEBI:31401
CHEMBL799
CID2754
CL23867
CPD000058428
Cilostazol
Cilostazol (JP15/USAN/INN)
Cilostazol [INN:JAN]
Cilostazole
Cilostazolum
Cilostazolum [INN-Latin]
D01896
DB01166
EU-0100218
HMS1922N15
HMS2093M14
KBio3_002259
KBioGR_001184
 
LS-142693
Lopac-C-0737
Lopac0_000218
MLS000028470
MLS000758281
MLS000759507
MLS001076067
MLS002153891
MolPort-001-758-007
NCGC00015207-01
NCGC00015207-02
NCGC00015207-06
NCGC00015207-10
NCGC00022153-02
NCGC00022153-04
NCGC00022153-05
NCGC00022153-06
NCGC00022153-07
OPC 13013
OPC 21
OPC-13013
OPC-21
Otsuka brand of cilostazol
Pletaal
Pletal
Pletal (TN)
Pletal, Cilostazol
S1294_Selleck
SAM001246734
SAM001247085
SMR000058428
SPBio_001256
SPECTRUM1505230
Spectrum2_001118
Spectrum3_001170
Spectrum4_000772
Spectrum5_001762
TL8005113
Tocris-1692
UNII-N7Z035406B
ZINC01552174
cilostazol
3
Clopidogrelapproved, nutraceuticalPhase 4674120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel Bisulfate
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
 
IDI1_000787
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
4Phosphodiesterase 3 InhibitorsPhase 4111
5Tissue Plasminogen ActivatorPhase 3198

Interventional clinical trials:

idNameStatusNCT IDPhase
1Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis IICompletedNCT00130039Phase 4
2A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial StenosisRecruitingNCT01553643Phase 4
3Basilar Artery International Cooperation StudyRecruitingNCT01717755Phase 3
4Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery OcclusionTerminatedNCT00123266Phase 2
5Multi MERCI (Mechanical Embolus Removal in Cerebral Ischemia [MERCI™])CompletedNCT00318071
6Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical TreatmentRecruitingNCT02441556

Search NIH Clinical Center for Basilar Artery Occlusion

Genetic Tests for Basilar Artery Occlusion

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Anatomical Context for Basilar Artery Occlusion

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MalaCards organs/tissues related to Basilar Artery Occlusion:

33
Brain

Animal Models for Basilar Artery Occlusion or affiliated genes

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MGI Mouse Phenotypes related to Basilar Artery Occlusion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.2ARRB1, ARRB2, F2, PANX1, PLAT, PLG
2MP:00053978.1ARRB2, F2, ITGA2B, PANX1, PLAT, PLG
3MP:00053767.0ARRB1, ARRB2, F2, ITGA2B, PANX1, PLAT
4MP:00053787.0ARRB1, ARRB2, CALD1, F2, FOSB, PLAT

Publications for Basilar Artery Occlusion

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Articles related to Basilar Artery Occlusion:

(show top 50)    (show all 237)
idTitleAuthorsYear
1
Initial factors affecting the clinical outcome after successful recanalization via MR-based mechanical thrombectomy in patients with acute ischemic stroke due to basilar artery occlusion. (26371295)
2015
2
Recanalization of basilar artery occlusion. (26219271)
2015
3
A novel route of revascularization in basilar artery occlusion and review of the literature. (26055597)
2015
4
Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever. (26156170)
2015
5
Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion. (25482105)
2015
6
Posterior circulation CT angiography collaterals predict outcome of endovascular acute ischemic stroke therapy for basilar artery occlusion. (26283714)
2015
7
Different Imaging Strategies in Patients With Possible Basilar Artery Occlusion: Cost-Effectiveness Analysis. (26022634)
2015
8
Intravenous Versus Intra-arterial Thrombolysis for Acute Ischemic Stroke Secondary to Basilar Artery Occlusion. (24765612)
2014
9
Forced Arterial Suction Thrombectomy with the Penumbra Reperfusion Catheter in Acute Basilar Artery Occlusion: A Retrospective Comparison Study in 2 Korean University Hospitals. (25034774)
2014
10
Childhood Basilar Artery Occlusion: A Report of 5 Cases and Review of the Literature. (23670249)
2013
11
Improved Clinical Outcome after Acute Basilar Artery Occlusion since the Introduction of Endovascular Thrombectomy Devices. (24246933)
2013
12
Mechanical Thrombectomy with Stent Retrievers in Acute Basilar Artery Occlusion. (24287087)
2013
13
The catastrophic basilar artery occlusion. (24064404)
2013
14
Endovascular mechanical thrombectomy in basilar artery occlusion: initial experience. (24167791)
2013
15
Outcomes of basilar artery occlusion in patients aged 75 years or older in the Basilar Artery International Cooperation Study. (22527236)
2012
16
Editorial: endovascular treatment of basilar artery occlusion: when a pretty picture is not enough. (21507123)
2012
17
EkoSonicSV endovascular system for recanalization of the basilar artery occlusion. (21948785)
2011
18
A case of recurrent basilar artery occlusion successfully treated with repeated intravascular procedures. (21364363)
2011
19
Diffusion weighted imaging reversibility in the brainstem following successful recanalization of acute basilar artery occlusion. (21990621)
2010
20
Acute aortic dissection mimicking basilar artery occlusion in a patient presenting with sudden coma. (20395144)
2010
21
CT angiography source images predict final infarct extent in patients with basilar artery occlusion. (19643923)
2009
22
Basilar artery occlusion following C1 lateral mass fracture managed by mechanical and pharmacological thrombolysis. (18956154)
2009
23
Unusual cause of acute neurologic deficit in childhood: primary central nervous system vasculitis presenting with basilar arterial occlusion. (18690464)
2009
24
Baclofen successfully abolished prolonged central hyperthermia in a patient with basilar artery occlusion. (19673364)
2009
25
Vertebral artery dissection complicated by basilar artery occlusion successfully treated with intra-arterial thrombolysis: three case reports. (18379743)
2008
26
Admission facility is associated with outcome of basilar artery occlusion. (17322095)
2007
27
Therapy of basilar artery occlusion: individual protocols needed. (17495220)
2007
28
Therapy of basilar artery occlusion: a systematic analysis comparing intra-arterial and intravenous thrombolysis. (16439705)
2006
29
Treatment and clinical outcome in patients with basilar artery occlusion. (16902170)
2006
30
Transcranial color-coded duplex sonography in suspected acute basilar artery occlusion. (16530089)
2006
31
Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. (14739412)
2004
32
Clinical and radiological predictors of recanalisation and outcome of 40 patients with acute basilar artery occlusion treated with intra-arterial thrombolysis. (15146000)
2004
33
Acute basilar artery occlusion treated by thromboaspiration in a cocaine and ecstasy abuser. (14504335)
2003
34
Relationship between findings of conventional and contrast-enhanced transcranial color-coded real-time sonography and angiography in patients with basilar artery occlusion. (11950645)
2002
35
Early thrombolysis in stroke due to basilar artery occlusion. (11917979)
2001
36
Massive pontine hemorrhagic infarction associated with embolic basilar artery occlusion. (11506312)
2001
37
Basilar artery occlusion due to spontaneous basilar artery dissection in a child. (10071693)
1999
38
Basilar artery occlusion in cryptococcal meningitis. (10514591)
1999
39
Development of cerebellar atrophy 15 years after basilar artery occlusion: hypoperfusion or coincidence? (9426261)
1997
40
Acute cerebellar edema following intra-arterial tissue plasminogen activator thrombolysis for basilar artery occlusion--case report. (8741376)
1996
41
Thrombolytic therapy of acute basilar artery occlusion. Variables affecting recanalization and outcome. (8623107)
1996
42
Herald hemiparesis of basilar artery occlusion suggested by Doppler sonography. (8273681)
1994
43
Bilateral anterior cerebral artery territory infarction in the differential diagnosis of basilar artery occlusion. (1573421)
1992
44
Infusion of recombinant tissue plasminogen activator for treatment of basilar artery occlusion. (2120803)
1990
45
Clinical features of proven basilar artery occlusion. (2389292)
1990
46
Distal basilar artery occlusion syndrome. (7199674)
1982
47
Basilar artery occlusion in childhood: report of a case. (420617)
1979
48
Basilar artery occlusion: clinical and radiological correlation. (860293)
1977
49
Prognostic value of visual evoked potentials in occipital blindness following basilar artery occlusion. (1221920)
1975
50
Basilar artery occlusion: report of a case with ten years' survival. (13585271)
1958

Variations for Basilar Artery Occlusion

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Expression for genes affiliated with Basilar Artery Occlusion

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Search GEO for disease gene expression data for Basilar Artery Occlusion.

Pathways for genes affiliated with Basilar Artery Occlusion

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GO Terms for genes affiliated with Basilar Artery Occlusion

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Cellular components related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:007256210.2F2, ITGA2B, PLG
2plasma membraneGO:00058866.3ARRB1, ARRB2, CALD1, F2, ITGA2B, PANX1

Biological processes related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of fibrinolysisGO:005191810.4F2, PLG
2negative regulation of proteolysisGO:004586110.3F2, PLAT
3fibrinolysisGO:004273010.2F2, PLAT, PLG
4follicle-stimulating hormone signaling pathwayGO:004269910.1ARRB1, ARRB2
5positive regulation of receptor internalizationGO:000209210.0ARRB1, ARRB2
6G-protein coupled receptor internalizationGO:00020319.9ARRB1, ARRB2
7response to corticosteroneGO:00514129.7FOSB, TRH
8positive regulation of protein phosphorylationGO:00019349.6ARRB1, ARRB2, F2
9platelet activationGO:00301688.8ARRB1, ARRB2, F2, ITGA2B, PLG
10blood coagulationGO:00075968.3ARRB1, ARRB2, F2, ITGA2B, PLAT, PLG

Molecular functions related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1alpha-1A adrenergic receptor bindingGO:003169110.0ARRB1, ARRB2
2alpha-1B adrenergic receptor bindingGO:003169210.0ARRB1, ARRB2
3angiotensin receptor bindingGO:003170110.0ARRB1, ARRB2
4follicle-stimulating hormone receptor bindingGO:003176210.0ARRB1, ARRB2
5serine-type endopeptidase activityGO:00042529.9F2, PLAT, PLG
6receptor bindingGO:00051028.9ARRB2, F2, PANX1, PLAT, PLG

Sources for Basilar Artery Occlusion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet