MCID: BSL004
MIFTS: 36

Basilar Artery Occlusion malady

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Basilar Artery Occlusion

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Summaries for Basilar Artery Occlusion

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MalaCards based summary: Basilar Artery Occlusion is related to unverricht-lundborg syndrome and inferolateral myocardial infarct. An important gene associated with Basilar Artery Occlusion is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways are Diuretics Pathway, Pharmacodynamics and Dissolution of Fibrin Clot. Affiliated tissues include brain, and related mouse phenotypes are respiratory system and hematopoietic system.

Related Diseases for Basilar Artery Occlusion

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Diseases related to Basilar Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
idRelated DiseaseScoreTop Affiliating Genes
1unverricht-lundborg syndrome10.3APOBEC3G, PLAT
2inferolateral myocardial infarct10.2ITGA2B, PLAT
3linear scleroderma10.2PLAT, PLG
4thunderclap headache10.2F2, ITGA2B
5peanut allergy10.2F2, PLAT
6colonic lymphangioma10.2ITGA2B, PLG
7hemarthrosis10.1F2, PLG
8clear cell chondrosarcoma10.1ITGA2B, PLG
9miller-dieker lissencephaly syndrome10.1F2, PLG
10cervix small cell carcinoma10.1F2, ITGA2B, PLAT
11influenza10.1F2, PLG
12mixed epithelial tumor of ovary10.1F2, PLG
13chronic fatigue syndrome10.1PLAT, PLG
14chorioretinal scar10.1F2, PLG
15mixed hepatoblastoma10.1F2, PLG
16alcoholic gastritis10.1F2, PLAT, PLG
17aneurysm10.1
18pregnancy loss, recurrent 110.1F2, PLAT, PLG
19ocular hyperemia10.0F2, ITGA2B, PLG
20schwannoma of jugular foramen10.0F2, PLG
21cerebritis10.0
22xeroderma pigmentosum, group b10.0ARRB1, ARRB2
23midline cystocele10.0F2, PLG
24thrombosis10.0
25ischemia10.0
26budd-chiari syndrome9.9F2, PLAT, PLG, TSPAN33
27seminoma9.9F2, PLG
28myocardial infarction9.9
29acute myocardial infarction9.9
30cervicitis9.9
31mutism9.9
32pontine hemorrhage9.9
33mobitz type ii atrioventricular block9.7F2, FOSB, PLG, SLC25A16
34duchenne muscular dystrophy9.7
35burns9.7
36hydrocephalus9.7
37cryptococcal meningitis9.7
38arteriovenous malformation9.7
39vertebral artery occlusion9.7
40choroiditis9.7
41cortical blindness9.7
42locked-in syndrome9.7
43syphilis9.7
44akinetic mutism9.7
45central nervous system vasculitis9.7
46vasculitis9.7
47meningitis9.7
48muscular dystrophy9.7
49headache9.7
50coccidioidomycosis8.2APOBEC3G, ARRB1, ARRB2, F2, FOSB, ITGA2B

Graphical network of the top 20 diseases related to Basilar Artery Occlusion:



Diseases related to basilar artery occlusion

Symptoms & Phenotypes for Basilar Artery Occlusion

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MGI Mouse Phenotypes related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.1ARRB1, ARRB2, F2, PANX1, PLAT, PLG
2MP:00053977.6ARRB1, ARRB2, F2, ITGA2B, PANX1, PLAT

Drugs & Therapeutics for Basilar Artery Occlusion

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Drugs for Basilar Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CilostazolapprovedPhase 410673963-72-12754
Synonyms:
3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
3,4-dihydro-6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one
6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
73963-72-1
89332-50-3
AC-4334
AC1L1EE2
BRD-K67017579-001-04-2
BRD-K67017579-001-05-9
BRD-K67017579-001-07-5
BRD-K67017579-001-13-3
BRN 3632107
BSPBio_002759
C 0737
C045645
C0737_SIGMA
C20H27N5O2
CHEBI:31401
CHEMBL799
CID2754
CL23867
CPD000058428
Cilostazol (JP15/USAN/INN)
Cilostazol [INN:JAN]
Cilostazole
Cilostazolum
Cilostazolum [INN-Latin]
D01896
DB01166
EU-0100218
HMS1922N15
HMS2093M14
KBio3_002259
KBioGR_001184
 
LS-142693
Lopac-C-0737
Lopac0_000218
MLS000028470
MLS000758281
MLS000759507
MLS001076067
MLS002153891
MolPort-001-758-007
NCGC00015207-01
NCGC00015207-02
NCGC00015207-06
NCGC00015207-10
NCGC00022153-02
NCGC00022153-04
NCGC00022153-05
NCGC00022153-06
NCGC00022153-07
OPC 13013
OPC 21
OPC-13013
OPC-21
Otsuka brand of cilostazol
Pletaal
Pletal
Pletal (TN)
Pletal, Cilostazol
S1294_Selleck
SAM001246734
SAM001247085
SMR000058428
SPBio_001256
SPECTRUM1505230
Spectrum2_001118
Spectrum3_001170
Spectrum4_000772
Spectrum5_001762
TL8005113
Tocris-1692
UNII-N7Z035406B
ZINC01552174
cilostazol
2
TiclopidineapprovedPhase 447155142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
3
Clopidogrelapproved, nutraceuticalPhase 4778120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
IDI1_000787
 
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
4Protective AgentsPhase 47443
5Platelet Aggregation InhibitorsPhase 42516
6Purinergic P2 Receptor AntagonistsPhase 4795
7Purinergic P2Y Receptor AntagonistsPhase 4793
8Anti-Asthmatic AgentsPhase 43488
9Respiratory System AgentsPhase 44997
10Vasodilator AgentsPhase 43543
11Phosphodiesterase InhibitorsPhase 41289
12Phosphodiesterase 3 InhibitorsPhase 4133
13Bronchodilator AgentsPhase 42965
14Autonomic AgentsPhase 410150
15Fibrinolytic AgentsPhase 4, Phase 22388
16Cytochrome P-450 Enzyme InhibitorsPhase 43917
17Peripheral Nervous System AgentsPhase 423689
18Neurotransmitter AgentsPhase 418340
19Neuroprotective AgentsPhase 41716
20Tissue Plasminogen ActivatorPhase 3238
21PlasminogenPhase 2242
22Central Nervous System Depressants13403
23Anesthetics9596

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial StenosisUnknown statusNCT01553643Phase 4
2Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis IICompletedNCT00130039Phase 4
3Basilar Artery International Cooperation StudyRecruitingNCT01717755Phase 3
4Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery OcclusionTerminatedNCT00123266Phase 2
5Multi MERCI (Mechanical Embolus Removal in Cerebral Ischemia [MERCI™])CompletedNCT00318071
6Basilar Artery Occlusion Chinese Endovascular TrialRecruitingNCT02737189
7Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical TreatmentRecruitingNCT02441556
8Chinese Registry of Assisted Embolization for Unruptured Wide Necked Intracranial Aneurysm Using LVIS StentRecruitingNCT02830373
9Variation of Cerebral Blood Flow in Anterior Cerebral and Basilar Artery in Neonates and Infants in Genreal Anesthesia With Caudal BlockEnrolling by invitationNCT02761954

Search NIH Clinical Center for Basilar Artery Occlusion

Genetic Tests for Basilar Artery Occlusion

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Anatomical Context for Basilar Artery Occlusion

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MalaCards organs/tissues related to Basilar Artery Occlusion:

36
Brain

Publications for Basilar Artery Occlusion

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Articles related to Basilar Artery Occlusion:

(show top 50)    (show all 265)
idTitleAuthorsYear
1
Intra-arterial Treatment for Basilar Artery Occlusion. (27893872)
2017
2
Intra-arterial Treatment for Basilar Artery Occlusion-Reply. (27893877)
2017
3
A leap forward in the endovascular management of acute basilar artery occlusion since the appearance of stent retrievers: a single-center comparative study. (27257830)
2016
4
Successful recanalization in acute basilar artery occlusion treated with endovascular therapy is independent of thrombus length. (27789788)
2016
5
Basilar artery occlusion in a child treated successfully with mechanical thrombectomy using ADAPT. (27068722)
2016
6
Revascularization of acute basilar artery occlusion using theA Tigertriever adjustable clot retriever. (27511204)
2016
7
Cocaine and Acute Basilar Artery Occlusion: What we Know to Date? (27633287)
2016
8
Neurologic Examination at 24 to 48 Hours Predicts Functional Outcomes in Basilar Artery Occlusion Stroke. (27586683)
2016
9
The challenge of basilar artery occlusion wake-up stroke: too late for intravenous thrombolysis? (26960980)
2016
10
Mechanical thrombectomy in acute basilar artery occlusion: A safety and efficacy single centre study. (26908588)
2016
11
Treatment of a Giant Fusiform Basilar Aneurysm with Partial Intra-Aneurysmal Embolization Combined with Mid-Basilar Artery Occlusion in a Child. (27116216)
2016
12
Thrombectomy using a stent retriever with artificially induced vertebral artery vasospasm in a patient with acute basilar artery occlusion: a case report. (26678752)
2016
13
Collateral flow predicts outcome after basilar artery occlusion: The posterior circulation collateral score. (27016515)
2016
14
Acute Ischemic Stroke Involving Both Anterior and Posterior Circulation Treated by Endovascular Revascularization for Acute Basilar Artery Occlusion via Persistent Primitive Trigeminal Artery. (27446523)
2016
15
Where did the clot go? An unusual complication of mechanical thrombectomy caused by malignancy related subclavian steal phenomenon in a patient with acute basilar artery occlusion. (27799374)
2016
16
Endovascular mechanical thrombectomy in basilar artery occlusion: variables affecting recanalization and outcome. (26872664)
2016
17
Where did the clot go? An unusual complication of mechanical thrombectomy caused by malignancy related subclavian steal phenomenon in a patient with acute basilar artery occlusion. (27797875)
2016
18
Functional Independence following Endovascular Treatment for Basilar Artery Occlusion despite Extensive Bilateral Pontine Infarcts on Diffusion-Weighted Imaging: Refuting a Self-Fulfilling Prophecy. (27781047)
2016
19
Safety and Outcome of Intra-Arterial Treatment for Basilar Artery Occlusion. (27532477)
2016
20
Coil Embolization for Ruptured Basilar Tip Aneurysm After Mechanical Thrombectomy for Acute Basilar Artery Occlusion. (27368502)
2016
21
Thrombectomy using Trevo ProVue Stent Retriever Devices after Recombinant Tissue Plasminogen Activator Thrombolysis for Acute Basilar Artery Occlusion during Vertebral Artery Dissection. (27086817)
2016
22
Basilar artery occlusion in a child treated successfully with mechanical thrombectomy using ADAPT. (27075484)
2016
23
Mechanical thrombectomy with the Solitaire AB stent for treatment of acute basilar artery occlusion: A single-center experience. (27312281)
2016
24
Intra-arterial revascularization therapy for basilar artery occlusion-a systematic review and analysis. (26810313)
2016
25
Endovascular Mechanical Thrombectomy with the Solitaire Device for the Treatment of Acute Basilar Artery Occlusion. (26875658)
2016
26
A Comparison between Mechanical Thrombectomy and Intra-arterial Fibrinolysis in Acute Basilar Artery Occlusion: Single Center Experiences. (27283281)
2016
27
Outcomes of stent retriever thrombectomy in basilar artery occlusion: an observational study and systematic review. (25986363)
2015
28
Posterior Circulation Acute Stroke Prognosis Early Computed Tomography Score Using Hypointense Vessels on Susceptibility Weighted Imaging Independently Predicts Outcome in Patients with Basilar Artery Occlusion. (26176682)
2015
29
Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever. (26156170)
2015
30
Significant period between presentation and diagnosis in basilar artery occlusion: five cases and the lessons learned. (25721014)
2015
31
Infarction of the choroid plexus in basilar artery occlusion. (26299694)
2015
32
Different Imaging Strategies in Patients With Possible Basilar Artery Occlusion: Cost-Effectiveness Analysis. (26022634)
2015
33
Predictors of Good Outcome After Stent-Retriever Thrombectomy in Acute Basilar Artery Occlusion. (26330448)
2015
34
A novel route of revascularization in basilar artery occlusion and review of the literature. (26055597)
2015
35
Basilar artery occlusion: Prognostic signs of severity on computed tomography. (25857713)
2015
36
Initial factors affecting the clinical outcome after successful recanalization via MR-based mechanical thrombectomy in patients with acute ischemic stroke due to basilar artery occlusion. (26371295)
2015
37
Recanalization of basilar artery occlusion. (26219271)
2015
38
Endovascular treatment of severe acute basilar artery occlusion. (25443091)
2015
39
A novel route of revascularization in basilar artery occlusion and review of the literature. (26063797)
2015
40
Time window for recanalization in basilar artery occlusion: Speculative synthesis. (26574535)
2015
41
Acute basilar artery occlusion: an easily missed uncommon but devastating emergency. (26238141)
2015
42
Endovascular treatment of acute basilar artery occlusion: time to treatment is crucial. (25703459)
2015
43
Posterior circulation CT angiography collaterals predict outcome of endovascular acute ischemic stroke therapy for basilar artery occlusion. (26283714)
2015
44
Outcomes of endovascular treatment of basilar artery occlusion in the stent retriever era: a systematic review and meta-analysis. (26610730)
2015
45
Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever. (26150626)
2015
46
Prodromal Transient Ischemic Attack or Minor Stroke and Outcome in Basilar Artery Occlusion. (26153508)
2015
47
Endovascular revascularization for basilar artery occlusion. (25999990)
2015
48
The use of mechanical thrombectomy in the treatment of basilar artery occlusion--case report. (26377986)
2015
49
Mechanical recanalization in basilar artery occlusion: the ENDOSTROKE study. (25516154)
2015
50
Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion. (25482105)
2015

Variations for Basilar Artery Occlusion

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Expression for genes affiliated with Basilar Artery Occlusion

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Search GEO for disease gene expression data for Basilar Artery Occlusion.

Pathways for genes affiliated with Basilar Artery Occlusion

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Pathways related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathwaysScoreTop Affiliating Genes
19.9ARRB2, SLC12A3
29.8PLAT, PLG
39.8PLAT, PLG
49.7F2, PLG
59.7F2, PLG
6
Show member pathways
9.5F2, PLAT, PLG
7
Show member pathways
9.5F2, PLAT, PLG
8
Show member pathways
9.0ARRB1, ARRB2, ITGA2B
9
Show member pathways
9.0ARRB1, ARRB2, F2
108.8ARRB1, ARRB2, FOSB
118.8ARRB1, ARRB2, FOSB
12
Show member pathways
8.0ARRB1, ARRB2, F2, ITGA2B, PLAT, PLG

GO Terms for genes affiliated with Basilar Artery Occlusion

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Cellular components related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:00058866.4ARRB1, ARRB2, F2, ITGA2B, PANX1, PLG

Biological processes related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of proteolysisGO:004586110.5F2, PLAT
2negative regulation of fibrinolysisGO:005191810.3F2, PLG
3fibrinolysisGO:004273010.1F2, PLAT, PLG
4follicle-stimulating hormone signaling pathwayGO:004269910.0ARRB1, ARRB2
5G-protein coupled receptor internalizationGO:000203110.0ARRB1, ARRB2
6negative regulation of interleukin-6 productionGO:003271510.0ARRB1, ARRB2
7platelet activationGO:00301689.6ARRB1, ARRB2, F2
8positive regulation of protein phosphorylationGO:00019349.4ARRB1, ARRB2, F2
9positive regulation of receptor internalizationGO:00020929.4ARRB1, ARRB2

Molecular functions related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1alpha-1A adrenergic receptor bindingGO:003169110.0ARRB1, ARRB2
2alpha-1B adrenergic receptor bindingGO:003169210.0ARRB1, ARRB2
3angiotensin receptor bindingGO:003170110.0ARRB1, ARRB2
4follicle-stimulating hormone receptor bindingGO:003176210.0ARRB1, ARRB2
5serine-type peptidase activityGO:00082369.5F2, PLAT, PLG
6receptor bindingGO:00051029.5ARRB2, F2, PANX1, PLAT, PLG

Sources for Basilar Artery Occlusion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet