MCID: BSL004
MIFTS: 31

Basilar Artery Occlusion malady

Category: Cardiovascular diseases

Aliases & Classifications for Basilar Artery Occlusion

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Aliases & Descriptions for Basilar Artery Occlusion:

Name: Basilar Artery Occlusion 11 13

Classifications:



External Ids:

Disease Ontology11 DOID:13446
ICD1028 I65.1
ICD9CM30 433.0

Summaries for Basilar Artery Occlusion

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MalaCards based summary: Basilar Artery Occlusion is related to anterior cerebral artery infarction and milk allergy. An important gene associated with Basilar Artery Occlusion is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways are Diuretics Pathway, Pharmacodynamics and MAP2K and MAPK activation. Affiliated tissues include brain.

Related Diseases for Basilar Artery Occlusion

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Graphical network of the top 20 diseases related to Basilar Artery Occlusion:



Diseases related to basilar artery occlusion

Symptoms for Basilar Artery Occlusion

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Drugs & Therapeutics for Basilar Artery Occlusion

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Drugs for Basilar Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TiclopidinePhase 443555142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
2
ClopidogrelPhase 4733120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
IDI1_000787
 
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
3
CilostazolPhase 410173963-72-12754
Synonyms:
3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
3,4-dihydro-6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one
6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
73963-72-1
89332-50-3
AC-4334
AC1L1EE2
BRD-K67017579-001-04-2
BRD-K67017579-001-05-9
BRD-K67017579-001-07-5
BRD-K67017579-001-13-3
BRN 3632107
BSPBio_002759
C 0737
C045645
C0737_SIGMA
C20H27N5O2
CHEBI:31401
CHEMBL799
CID2754
CL23867
CPD000058428
Cilostazol (JP15/USAN/INN)
Cilostazol [INN:JAN]
Cilostazole
Cilostazolum
Cilostazolum [INN-Latin]
D01896
DB01166
EU-0100218
HMS1922N15
HMS2093M14
KBio3_002259
KBioGR_001184
 
LS-142693
Lopac-C-0737
Lopac0_000218
MLS000028470
MLS000758281
MLS000759507
MLS001076067
MLS002153891
MolPort-001-758-007
NCGC00015207-01
NCGC00015207-02
NCGC00015207-06
NCGC00015207-10
NCGC00022153-02
NCGC00022153-04
NCGC00022153-05
NCGC00022153-06
NCGC00022153-07
OPC 13013
OPC 21
OPC-13013
OPC-21
Otsuka brand of cilostazol
Pletaal
Pletal
Pletal (TN)
Pletal, Cilostazol
S1294_Selleck
SAM001246734
SAM001247085
SMR000058428
SPBio_001256
SPECTRUM1505230
Spectrum2_001118
Spectrum3_001170
Spectrum4_000772
Spectrum5_001762
TL8005113
Tocris-1692
UNII-N7Z035406B
ZINC01552174
cilostazol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis IICompletedNCT00130039Phase 4
2A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial StenosisRecruitingNCT01553643Phase 4
3Basilar Artery International Cooperation StudyRecruitingNCT01717755Phase 3
4Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery OcclusionTerminatedNCT00123266Phase 2
5Multi MERCI (Mechanical Embolus Removal in Cerebral Ischemia [MERCI™])CompletedNCT00318071
6Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical TreatmentRecruitingNCT02441556
7Chinese Registry of Assisted Embolization for Unruptured Wide Necked Intracranial Aneurysm Using LVIS StentRecruitingNCT02830373
8Variation of Cerebral Blood Flow in Anterior Cerebral and Basilar Artery in Neonates and Infants in Genreal Anesthesia With Caudal BlockEnrolling by invitationNCT02761954
9Basilar Artery Occlusion Chinese Endovascular TrialNot yet recruitingNCT02737189

Search NIH Clinical Center for Basilar Artery Occlusion

Genetic Tests for Basilar Artery Occlusion

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Anatomical Context for Basilar Artery Occlusion

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MalaCards organs/tissues related to Basilar Artery Occlusion:

34
Brain

Animal Models for Basilar Artery Occlusion or affiliated genes

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Publications for Basilar Artery Occlusion

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Articles related to Basilar Artery Occlusion:

(show top 50)    (show all 259)
idTitleAuthorsYear
1
Treatment of a Giant Fusiform Basilar Aneurysm with Partial Intra-Aneurysmal Embolization Combined with Mid-Basilar Artery Occlusion in a Child. (27116216)
2016
2
Acute Ischemic Stroke Involving Both Anterior and Posterior Circulation Treated by Endovascular Revascularization for Acute Basilar Artery Occlusion via Persistent Primitive Trigeminal Artery. (27446523)
2016
3
Thrombectomy using a stent retriever with artificially induced vertebral artery vasospasm in a patient with acute basilar artery occlusion: a case report. (26678752)
2016
4
Initial factors affecting the clinical outcome after successful recanalization via MR-based mechanical thrombectomy in patients with acute ischemic stroke due to basilar artery occlusion. (26371295)
2015
5
A novel route of revascularization in basilar artery occlusion and review of the literature. (26055597)
2015
6
Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion. (25482105)
2015
7
Different Imaging Strategies in Patients With Possible Basilar Artery Occlusion: Cost-Effectiveness Analysis. (26022634)
2015
8
Mechanical recanalization in basilar artery occlusion: the ENDOSTROKE study. (25516154)
2015
9
Endovascular treatment of acute basilar artery occlusion: time to treatment is crucial. (25703459)
2015
10
A novel route of revascularization in basilar artery occlusion and review of the literature. (26063797)
2015
11
Intravenous Versus Intra-arterial Thrombolysis for Acute Ischemic Stroke Secondary to Basilar Artery Occlusion. (24765612)
2014
12
Outcome predictors in acute basilar artery occlusion. (24718823)
2014
13
Acute Basilar Artery Occlusion with Underlying High-Grade Basilar Artery Stenosis: Multimodal Endovascular Therapy in a Series of Seven Patients. (24727890)
2014
14
Sudden bilateral deafness revealing fatal basilar artery occlusion. (24647750)
2014
15
Improved Clinical Outcome after Acute Basilar Artery Occlusion since the Introduction of Endovascular Thrombectomy Devices. (24246933)
2013
16
Mechanical Thrombectomy with Stent Retrievers in Acute Basilar Artery Occlusion. (24287087)
2013
17
Endovascular mechanical thrombectomy in basilar artery occlusion: initial experience. (24167791)
2013
18
Endovascular recanalisation therapy for prolonged basilar artery occlusion based on clinical-diffusion MRI mismatch. (23021202)
2013
19
Basilar artery occlusion in migraine-like headache: a possible triggering effect of sumatriptan. (21681368)
2012
20
Basilar artery occlusion after acute myocardial infarction. (21937130)
2012
21
Teaching neuroimages: locked-in syndrome resulting from traumatic basilar artery occlusion following clivus fracture. (22689739)
2012
22
MRI in patients with acute basilar artery occlusion - DWI lesion scoring is an independent predictor of outcome. (22151607)
2012
23
A case of recurrent basilar artery occlusion successfully treated with repeated intravascular procedures. (21364363)
2011
24
Intravenous thrombolysis of basilar artery occlusion: predictors of recanalization and outcome. (21737807)
2011
25
Three-month and long-term outcomes and their predictors in acute basilar artery occlusion treated with intra-arterial thrombolysis. (21546481)
2011
26
Basilar artery occlusion in a 14-year old female successfully treated with acute intravascular intervention: case report and review of the literature. (21276116)
2011
27
Acute aortic dissection mimicking basilar artery occlusion in a patient presenting with sudden coma. (20395144)
2010
28
Transient basilar artery occlusion monitored by transcranial color Doppler presenting with a spectacular shrinking deficit: a case report. (20205759)
2010
29
CT angiography source images predict final infarct extent in patients with basilar artery occlusion. (19643923)
2009
30
Unusual cause of acute neurologic deficit in childhood: primary central nervous system vasculitis presenting with basilar arterial occlusion. (18690464)
2009
31
Baclofen successfully abolished prolonged central hyperthermia in a patient with basilar artery occlusion. (19673364)
2009
32
Treatment of basilar artery occlusion: a prospective randomised therapeutic study is needed. (19909904)
2009
33
Vertebral artery dissection complicated by basilar artery occlusion successfully treated with intra-arterial thrombolysis: three case reports. (18379743)
2008
34
Endovascular recanalization of basilar artery occlusion 80 days after symptom onset. (17322092)
2007
35
Therapy of basilar artery occlusion: a systematic analysis comparing intra-arterial and intravenous thrombolysis. (16439705)
2006
36
Transcranial color-coded duplex sonography in suspected acute basilar artery occlusion. (16530089)
2006
37
Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. (14739412)
2004
38
Clinical and radiological predictors of recanalisation and outcome of 40 patients with acute basilar artery occlusion treated with intra-arterial thrombolysis. (15146000)
2004
39
Magnetic resonance imaging in basilar artery occlusion. (11890843)
2002
40
Bilateral deafness as a prodromal symptom of basilar artery occlusion. (11790395)
2002
41
Early thrombolysis in stroke due to basilar artery occlusion. (11917979)
2001
42
Basilar artery occlusion. (10769506)
2000
43
Basilar artery occlusion in a child: "clot angioplasty" followed by thrombolysis. (11007500)
2000
44
Basilar artery occlusion due to spontaneous basilar artery dissection in a child. (10071693)
1999
45
Basilar artery occlusion in cryptococcal meningitis. (10514591)
1999
46
Acute cerebellar edema following intra-arterial tissue plasminogen activator thrombolysis for basilar artery occlusion--case report. (8741376)
1996
47
Clinical features of proven basilar artery occlusion. (2389292)
1990
48
Early diagnosis of basilar artery occlusion using magnetic resonance imaging. (3354012)
1988
49
Distal basilar artery occlusion syndrome. (7199674)
1982
50
Basilar artery occlusion in childhood: report of a case. (420617)
1979

Variations for Basilar Artery Occlusion

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Expression for genes affiliated with Basilar Artery Occlusion

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Search GEO for disease gene expression data for Basilar Artery Occlusion.

Pathways for genes affiliated with Basilar Artery Occlusion

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GO Terms for genes affiliated with Basilar Artery Occlusion

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Biological processes related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1fibrinolysisGO:004273010.3F2, PLAT
2negative regulation of proteolysisGO:00458619.9F2, PLAT
3regulation of G-protein coupled receptor protein signaling pathwayGO:00082779.9ARRB1, ARRB2
4follicle-stimulating hormone signaling pathwayGO:00426999.8ARRB1, ARRB2
5negative regulation of interleukin-6 productionGO:00327159.8ARRB1, ARRB2
6negative regulation of GTPase activityGO:00342609.6ARRB1, ARRB2
7negative regulation of protein ubiquitinationGO:00313979.5ARRB1, ARRB2
8positive regulation of protein phosphorylationGO:00019349.4ARRB1, ARRB2, F2
9G-protein coupled receptor internalizationGO:00020319.4ARRB1, ARRB2
10positive regulation of receptor internalizationGO:00020929.3ARRB1, ARRB2
11platelet activationGO:00301689.2ARRB1, ARRB2, F2
12transmembrane transportGO:00550859.1MRS2, PANX1, SLC25A16

Molecular functions related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1alpha-1B adrenergic receptor bindingGO:00316929.8ARRB1, ARRB2
2alpha-1A adrenergic receptor bindingGO:00316919.8ARRB1, ARRB2
3follicle-stimulating hormone receptor bindingGO:00317629.8ARRB1, ARRB2
4phosphoprotein bindingGO:00512199.3ARRB1, PLAT
5angiotensin receptor bindingGO:00317019.1ARRB1, ARRB2
6receptor bindingGO:00051029.0ARRB2, F2, PANX1, PLAT

Sources for Basilar Artery Occlusion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet