MCID: BSL004
MIFTS: 34

Basilar Artery Occlusion malady

Category: Cardiovascular diseases

Aliases & Classifications for Basilar Artery Occlusion

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Aliases & Descriptions for Basilar Artery Occlusion:

Name: Basilar Artery Occlusion 10 12

Classifications:



External Ids:

Disease Ontology10 DOID:13446
ICD1027 I65.1
ICD9CM29 433.0
UMLS65 C0265098

Summaries for Basilar Artery Occlusion

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MalaCards based summary: Basilar Artery Occlusion is related to limb deficiencies distal with micrognathia and esophagus melanoma. An important gene associated with Basilar Artery Occlusion is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways are A-beta Pathways: Plaque Formation and APP Metabolism and Dissolution of Fibrin Clot. Affiliated tissues include breast, lung and skin, and related mouse phenotypes are respiratory system and hematopoietic system.

Related Diseases for Basilar Artery Occlusion

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Diseases related to Basilar Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 200)
idRelated DiseaseScoreTop Affiliating Genes
1limb deficiencies distal with micrognathia10.5PLAT, PLG
2esophagus melanoma10.4F2, PLG
3cyclothymic disorder10.4F2, PLG
4cavernous hemangioma of colon10.4F2, PLG
5acquired thrombocytopenia10.4F2, ITGA2B
6abducens nerve neoplasm10.4F2, PLG
7ovarian cancer10.4
8endotheliitis10.4
9west nile encephalitis10.4F2, PLG
10nephropathia epidemica10.3F2, PLG
11kidney fibrosarcoma10.3ITGA2B, PLAT, PLG
12eccrine sweat gland neoplasm10.3F2, PLG
13blood platelet disease10.3F2, ITGA2B
14colonic pseudo-obstruction10.3F2, PLAT
15adult acute lymphocytic leukemia10.3ITGA2B, PLAT, PLG
16thyroiditis10.3
17thrombophilia due to activated protein c resistance10.3F2, PLAT, PLG
18capillariasis10.3F2, ITGA2B, PLG
19heterophyiasis10.3ITGA2B, PLG
20spleen cancer10.3F2, ITGA2B, PLAT
21mitochondrial metabolism disease10.3F2, ITGA2B, PLG
22systemic lupus erythematosus10.2
23breast cancer10.2
24bacteremia10.2
25arthritis10.2
26hemangioma10.2
27hepatitis10.2
28lymphoma10.2
29down syndrome10.2
30prostatitis10.2
31vaginitis10.2
32focal epilepsy10.2
33retinitis10.2
34kidney disease10.2
35myocarditis10.2
36lupus erythematosus10.2
37learning disability10.2
38encephalitis10.2
39tetanus10.2PLG, SLC25A16
40dysgnathia complex10.2F2, PLAT
41thrombocytopenia cerebellar hypoplasia short stature10.2F2, ITGA2B
42morbid obesity10.2MRS2, PLAT, PLG
43glycerol kinase deficiency, adult form10.2PLAT, PLG
44whim syndrome10.2ARRB1, ARRB2
45pericardium disease10.1F2, ITGA2B, PLG
46stroke, ischemic10.1F2, PLAT, PLG, TSPAN33
47neuroblastoma10.1
48colorectal cancer10.1
49malaria10.1
50lung cancer10.1

Graphical network of the top 20 diseases related to Basilar Artery Occlusion:



Diseases related to basilar artery occlusion

Symptoms for Basilar Artery Occlusion

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Drugs & Therapeutics for Basilar Artery Occlusion

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Drugs for Basilar Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CilostazolapprovedPhase 410073963-72-12754
Synonyms:
3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
3,4-dihydro-6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one
6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
73963-72-1
89332-50-3
AC-4334
AC1L1EE2
BRD-K67017579-001-04-2
BRD-K67017579-001-05-9
BRD-K67017579-001-07-5
BRD-K67017579-001-13-3
BRN 3632107
BSPBio_002759
C 0737
C045645
C0737_SIGMA
C20H27N5O2
CHEBI:31401
CHEMBL799
CID2754
CL23867
CPD000058428
Cilostazol
Cilostazol (JP15/USAN/INN)
Cilostazol [INN:JAN]
Cilostazole
Cilostazolum
Cilostazolum [INN-Latin]
D01896
DB01166
EU-0100218
HMS1922N15
HMS2093M14
KBio3_002259
KBioGR_001184
 
LS-142693
Lopac-C-0737
Lopac0_000218
MLS000028470
MLS000758281
MLS000759507
MLS001076067
MLS002153891
MolPort-001-758-007
NCGC00015207-01
NCGC00015207-02
NCGC00015207-06
NCGC00015207-10
NCGC00022153-02
NCGC00022153-04
NCGC00022153-05
NCGC00022153-06
NCGC00022153-07
OPC 13013
OPC 21
OPC-13013
OPC-21
Otsuka brand of cilostazol
Pletaal
Pletal
Pletal (TN)
Pletal, Cilostazol
S1294_Selleck
SAM001246734
SAM001247085
SMR000058428
SPBio_001256
SPECTRUM1505230
Spectrum2_001118
Spectrum3_001170
Spectrum4_000772
Spectrum5_001762
TL8005113
Tocris-1692
UNII-N7Z035406B
ZINC01552174
cilostazol
2
TiclopidineapprovedPhase 419355142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
3
Clopidogrelapproved, nutraceuticalPhase 4717120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel Bisulfate
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
 
IDI1_000787
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
4Protective AgentsPhase 45651
5Platelet Aggregation InhibitorsPhase 41935
6Purinergic P2 Receptor AntagonistsPhase 4656
7Respiratory System AgentsPhase 43931
8Anti-Asthmatic AgentsPhase 42796
9Vasodilator AgentsPhase 42926
10Purinergic P2Y Receptor AntagonistsPhase 4654
11Phosphodiesterase InhibitorsPhase 41062
12Cytochrome P-450 Enzyme InhibitorsPhase 43036
13Bronchodilator AgentsPhase 42377
14Phosphodiesterase 3 InhibitorsPhase 4113
15Fibrinolytic AgentsPhase 4, Phase 21567
16Neuroprotective AgentsPhase 41376
17Peripheral Nervous System AgentsPhase 418510
18Neurotransmitter AgentsPhase 414795
19Tissue Plasminogen ActivatorPhase 3202
20PlasminogenPhase 2198
21Anesthetics7385

Interventional clinical trials:

idNameStatusNCT IDPhase
1Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis IICompletedNCT00130039Phase 4
2A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial StenosisRecruitingNCT01553643Phase 4
3Basilar Artery International Cooperation StudyRecruitingNCT01717755Phase 3
4Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery OcclusionTerminatedNCT00123266Phase 2
5Multi MERCI (Mechanical Embolus Removal in Cerebral Ischemia [MERCI™])CompletedNCT00318071
6Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical TreatmentRecruitingNCT02441556
7Variation of Cerebral Blood Flow in Anterior Cerebral and Basilar Artery in Neonates and Infants in Genreal Anesthesia With Caudal BlockEnrolling by invitationNCT02761954
8Basilar Artery Occlusion Chinese Endovascular TrialNot yet recruitingNCT02737189

Search NIH Clinical Center for Basilar Artery Occlusion

Genetic Tests for Basilar Artery Occlusion

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Anatomical Context for Basilar Artery Occlusion

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MalaCards organs/tissues related to Basilar Artery Occlusion:

33
Breast, Lung, Skin, Endothelial, T cells, Liver, Testes

Animal Models for Basilar Artery Occlusion or affiliated genes

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MGI Mouse Phenotypes related to Basilar Artery Occlusion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.3ARRB1, ARRB2, F2, PANX1, PLAT, PLG
2MP:00053977.4ARRB1, ARRB2, F2, ITGA2B, PANX1, PLAT

Publications for Basilar Artery Occlusion

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Articles related to Basilar Artery Occlusion:

(show top 50)    (show all 238)
idTitleAuthorsYear
1
Association of BAFF -871C/T Promoter Polymorphism with Hepatitis C-Related Mixed Cryoglobulinemia in a Cohort of Egyptian Patients. (25800158)
2015
2
Histologic classification of thymoma: a practical guide for routine cases. (25396309)
2014
3
Clinical features and genetic analysis of three patients with severe hypertriglyceridaemia. (24591733)
2014
4
N-cadherin impedes proliferation of the multiple myeloma cancer stem cells. (24396705)
2013
5
Efficacy of hyaluronic acid injections in patients with osteoarthritis of the temporomandibular joint. A comparative study. (24220392)
2013
6
Loss of phosphatase and tensin homolog expression is associated with recurrence and poor prognosis in patients with pancreatic ductal adenocarcinoma. (23260327)
2013
7
Septic implantation syndrome in dogs and cats: a distinct pattern of endophthalmitis with lenticular abscess. (22812929)
2013
8
A Novel PRPF31 Mutation in a Large Chinese Family with Autosomal Dominant Retinitis Pigmentosa and Macular Degeneration. (24244300)
2013
9
A genome-wide association study identifies five loci influencing facial morphology in Europeans. (23028347)
2012
10
Two PDZ binding motifs within NS5 have roles in Tick-borne encephalitis virus replication. (22796133)
2012
11
Clinically biphasic myasthenia gravis with both AChR and MuSK antibodies. (22955633)
2012
12
Meta-analysis of an association of codon 72 polymorphisms of the p53 gene with increased endometrial cancer risk. (22057999)
2011
13
Screening for Cushing's syndrome in an era of epidemic obesity. (21568231)
2011
14
Diff-Quik cytologic recognition of Chlamydophila psittaci in orolabial lesions of Stevens-Johnson Syndrome. (20968157)
2010
15
Clinical spectrum of desquamative inflammatory vaginitis. (21308558)
2010
16
Identification of a new HIV type 1 circulating BF intersubtype recombinant form (CRF47_BF) in Spain. (20618102)
2010
17
Increased estrogen rather than decreased androgen action is associated with longer androgen receptor CAG repeats. (18840639)
2009
18
A postmenopausal patient with Tangier disease developing SjAPgren's syndrome. (19208541)
2009
19
Chlorproguanil-dapsone-artesunate versus chlorproguanil-dapsone: a randomized, double-blind, phase III trial in African children, adolescents, and adults with uncomplicated Plasmodium falciparum malaria. (19996424)
2009
20
Hereditary angioedema: new hopes for an orphan disease. (19160940)
2008
21
Associations of age-dependent IGF-I SDS with cardiovascular diseases and risk conditions: cross-sectional study in 6773 primary care patients. (18230821)
2008
22
A new APOA1 mutation with severe HDL-cholesterol deficiency and premature coronary artery disease. (17991432)
2008
23
Diagnostic accuracy of ELISA and xMAP technology for analysis of amyloid beta(42) and tau proteins. (17395712)
2007
24
The coming problem of HIV-associated Alzheimer's disease. (17433562)
2007
25
Thoracic outlet syndrome in a competitive baseball player secondary to the anomalous insertion of an atrophic pectoralis minor muscle: a case report. (16476910)
2006
26
Premature menopause in association with blepharophimosis, ptosis, and epicanthus inversus. (16147759)
2005
27
Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells. (16169197)
2005
28
Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation. (15699019)
2005
29
Biochemical and etiological characteristics of acute hyponatremia in the emergency department. (16243191)
2005
30
Gliomatosis cerebri and pituitary adenoma: case report and literature review. (16132522)
2005
31
Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. (12835311)
2003
32
The effect of pH on beta(2) adrenoceptor function. Evidence for protonation-dependent activation. (10652295)
2000
33
Truncated thioredoxin is a mitogenic cytokine for resting human peripheral blood mononuclear cells and is present in human plasma. (10982790)
2000
34
Sequence requirement for the nucleolar localization of human I-mfa domain-containing protein (HIC p40). (11139147)
2000
35
Does thrombophilia play an aetiological role in Legg-CalvAc-Perthes disease? (10463746)
1999
36
Genomic organization, expression, and chromosome location of the human SNAIL gene (SNAI1) and a related processed pseudogene (SNAI1P). (10585766)
1999
37
Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics. (9120316)
1997
38
Genomic organization of the human bone morphogenetic protein-4 gene: molecular basis for multiple transcripts. (8645259)
1996
39
Characterization of vasoactive intestinal peptide receptors on human megakaryocytes and platelets. (8639831)
1996
40
Ferrochelatase cDNA delivered by adenoviral vector corrects biochemical defect in protoporphyric cells. (8590732)
1995
41
Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. (7671262)
1995
42
Expression of distinct fucosylated oligosaccharides and carbohydrate-mediated adhesion efficiency directed by two different alpha-1,3-fucosyltransferases. Comparison of E- and L-selectin-mediated adhesion. (7528213)
1994
43
Direct sequence analysis of TCR V delta 2-D delta 3 rearrangements in common acute lymphoblastic leukaemia and application to detection of minimal residual disease. (8217823)
1993
44
X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants. (1656049)
1991
45
Acquired focal dystonia following recovery from central pontine myelinolysis. (3225594)
1988
46
Sigma region located between C mu and C delta genes of human immunoglobulin heavy chain: possible involvement of tRNA-like structure in RNA splicing. (3141902)
1988
47
Morphometric study of hepatic ultrastructure in alcoholic hepatitis. Veterans Administration Cooperative Study Group on Alcoholic Hepatitis. (2980746)
1987
48
Overview: cerebrovascular accident and the hospitalized elderly--a multidimensional clinical problem. (6129808)
1983
49
50

Variations for Basilar Artery Occlusion

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Expression for genes affiliated with Basilar Artery Occlusion

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Search GEO for disease gene expression data for Basilar Artery Occlusion.

Pathways for genes affiliated with Basilar Artery Occlusion

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GO Terms for genes affiliated with Basilar Artery Occlusion

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Biological processes related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1follicle-stimulating hormone signaling pathwayGO:00426999.8ARRB1, ARRB2
2negative regulation of GTPase activityGO:00342609.6ARRB1, ARRB2
3negative regulation of interleukin-6 productionGO:00327159.5ARRB1, ARRB2

Molecular functions related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1alpha-1A adrenergic receptor bindingGO:00316919.6ARRB1, ARRB2

Sources for Basilar Artery Occlusion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet