MCID: BSL004
MIFTS: 34

Basilar Artery Occlusion

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Basilar Artery Occlusion

MalaCards integrated aliases for Basilar Artery Occlusion:

Name: Basilar Artery Occlusion 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:13446
ICD10 33 I65.1
ICD9CM 35 433.0
UMLS 69 C0265098

Summaries for Basilar Artery Occlusion

MalaCards based summary : Basilar Artery Occlusion is related to lin-gettig syndrome and lateral myocardial infarction. An important gene associated with Basilar Artery Occlusion is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and ADP signalling through P2Y purinoceptor 1. The drugs Tissue Plasminogen Activator and Fibrinolytic Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, and related phenotype is respiratory system.

Related Diseases for Basilar Artery Occlusion

Diseases related to Basilar Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
id Related Disease Score Top Affiliating Genes
1 lin-gettig syndrome 10.8 PLAT PLG
2 lateral myocardial infarction 10.7 PLAT PLG
3 bladder squamous papilloma 10.7 PLAT PLG
4 chronic wasting disease 10.7 APOBEC3G PLG
5 internal auditory canal meningioma 10.6 PLAT PLG
6 periosteal chondrosarcoma 10.6 ITGA2B PLG
7 hyperthyroidism 10.6 F2 PLG
8 pyridoxine deficiency anemia 10.6 F2 PLG
9 myiasis 10.6 F2 PLG
10 rectum neuroendocrine neoplasm 10.6 F2 PLG
11 mechanical entropion 10.6 PLAT TSPAN33
12 syndactyly, mesoaxial synostotic, with phalangeal reduction 10.6 F2 PLG
13 midline cystocele 10.5 F2 PLG
14 optic nerve neoplasm 10.5 ITGA2B PLAT
15 littre gland carcinoma 10.5 F2 PLG
16 arcus senilis 10.5 PLG SLC25A16
17 brain stem glioma 10.5 F2 PLG
18 central nervous system germ cell tumor 10.5 F2 PLG
19 lymphatic system cancer 10.5 F2 PLAT
20 hypopharynx cancer 10.5 PLAT PLG
21 parasitic helminthiasis infectious disease 10.4 ITGA2B PLAT PLG
22 lujo hemorrhagic fever 10.4 F2 PLG
23 cryptosporidiosis 10.4 F2 PLG
24 egg allergy 10.4 F2 PLAT PLG
25 aryepiglottic fold cancer 10.4 F2 PLAT PLG
26 thrombophilia due to activated protein c resistance 10.4 F2 PLAT PLG
27 brill-zinsser disease 10.4 F2 PLAT PLG
28 bone remodeling disease 10.4 F2 PLAT PLG
29 intestinal pseudo-obstruction 10.3 F2 PLAT
30 barbiturate abuse 10.3 PLAT PLG
31 mobitz type ii atrioventricular block 10.3 FOSB PLG SLC25A16
32 essential thrombocythemia 10.3 F2 ITGA2B
33 ocular hyperemia 10.2 F2 ITGA2B PLG
34 kondoh syndrome 10.2 F2 PLAT
35 malignant type ab thymoma 10.2 F2 ITGA2B PLAT
36 heart disease 10.1 FOSB TSPAN33
37 aneurysm 10.1
38 status asthmaticus 10.1 PLAT PLG
39 cerebritis 10.0
40 peripheral artery disease 10.0 F2 PLAT PLG
41 thrombosis 10.0
42 ischemia 10.0
43 stroke, ischemic 9.9 F2 PLAT PLG TSPAN33
44 pontine hemorrhage 9.9
45 cervicitis 9.9
46 myocardial infarction 9.9
47 mutism 9.9
48 acute myocardial infarction 9.9
49 hydrocephalus 9.7
50 meningitis 9.7

Graphical network of the top 20 diseases related to Basilar Artery Occlusion:



Diseases related to Basilar Artery Occlusion

Symptoms & Phenotypes for Basilar Artery Occlusion

MGI Mouse Phenotypes related to Basilar Artery Occlusion:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.1 ARRB1 ARRB2 F2 PANX1 PLAT PLG

Drugs & Therapeutics for Basilar Artery Occlusion

Drugs for Basilar Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Tissue Plasminogen Activator Phase 3
2 Fibrinolytic Agents Phase 2
3 Plasminogen Phase 2
4 Anesthetics
5 Central Nervous System Depressants

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial Stenosis Unknown status NCT01553643 Phase 4 Chinese Herb Huang-Chi-Wu-Wu-Tang;placebo
2 Basilar Artery International Cooperation Study Recruiting NCT01717755 Phase 3
3 Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery Occlusion Terminated NCT00123266 Phase 2 Microplasmin
4 Basilar Artery Occlusion Chinese Endovascular Trial Recruiting NCT02737189 Medical Treatment
5 Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical Treatment Recruiting NCT02441556
6 Chinese Registry of Assisted Embolization for Unruptured Wide Necked Intracranial Aneurysm Using LVIS Stent Recruiting NCT02830373
7 Variation of Cerebral Blood Flow in Anterior Cerebral and Basilar Artery in Neonates and Infants in Genreal Anesthesia With Caudal Block Enrolling by invitation NCT02761954

Search NIH Clinical Center for Basilar Artery Occlusion

Genetic Tests for Basilar Artery Occlusion

Anatomical Context for Basilar Artery Occlusion

MalaCards organs/tissues related to Basilar Artery Occlusion:

39
Brain

Publications for Basilar Artery Occlusion

Articles related to Basilar Artery Occlusion:

(show top 50) (show all 280)
id Title Authors Year
1
Efficacy and safety of direct aspiration first pass technique versus stent-retriever thrombectomy in acute basilar artery occlusion-a retrospective single center experience. ( 28251328 )
2017
2
Treatment of acute basilar artery occlusion: Systematic review and meta-analysis. ( 28823413 )
2017
3
Mechanical Thrombectomy for Acute Basilar Artery Occlusion in Early Therapeutic Time Window. ( 28848166 )
2017
4
Clinical Outcomes of Patients with Acute Basilar Artery Occlusion in Brazil: An Observational Study. ( 28551292 )
2017
5
Concomitant carotid aplasia and basilar artery occlusion in a child with PHACES syndrome. ( 28814594 )
2017
6
Intra-arterial Treatment for Basilar Artery Occlusion. ( 27893872 )
2017
7
The efficiency analysis of thrombolytic rt-PA combined with intravascular interventional therapy in patients with acute basilar artery occlusion. ( 28123346 )
2017
8
Dominant vertebral artery status and functional outcome after endovascular therapy of symptomatic basilar artery occlusion. ( 28131432 )
2017
9
Acute Basilar Artery Occlusion: Differences in Characteristics and Outcomes after Endovascular Therapy between Patients with and without Underlying Severe Atherosclerotic Stenosis. ( 28546252 )
2017
10
Acute superior mesenteric artery occlusion complicated by basilar artery occlusion. ( 28828111 )
2017
11
Intra-arterial Treatment for Basilar Artery Occlusion-Reply. ( 27893877 )
2017
12
ADC quantification in basilar artery occlusion as an indicator of clinical outcome after endovascular treatment. ( 28699370 )
2017
13
The Basilar Artery on Computed Tomography Angiography Prognostic Score for Basilar Artery Occlusion. ( 28228577 )
2017
14
Neuroimaging Predictors of Clinical Outcome in Acute Basilar Artery Occlusion. ( 28674517 )
2017
15
Acute basilar artery occlusion: Endovascular Interventions versus Standard Medical Treatment (BEST) Trial-Design and protocol for a randomized, controlled, multicenter study. ( 28361616 )
2017
16
Child Neurology: Childhood basilar artery occlusion and stroke. ( 28808172 )
2017
17
Endovascular mechanical thrombectomy in basilar artery occlusion: variables affecting recanalization and outcome. ( 26872664 )
2016
18
Endovascular Mechanical Thrombectomy with the Solitaire Device for the Treatment of Acute Basilar Artery Occlusion. ( 26875658 )
2016
19
Where did the clot go? An unusual complication of mechanical thrombectomy caused by malignancy related subclavian steal phenomenon in a patient with acute basilar artery occlusion. ( 27799374 )
2016
20
Coil Embolization for Ruptured Basilar Tip Aneurysm After Mechanical Thrombectomy for Acute Basilar Artery Occlusion. ( 27368502 )
2016
21
Successful recanalization in acute basilar artery occlusion treated with endovascular therapy is independent of thrombus length. ( 27789788 )
2016
22
Thrombectomy using Trevo ProVue Stent Retriever Devices after Recombinant Tissue Plasminogen Activator Thrombolysis for Acute Basilar Artery Occlusion during Vertebral Artery Dissection. ( 27086817 )
2016
23
Cocaine and Acute Basilar Artery Occlusion: What we Know to Date? ( 27633287 )
2016
24
Acute Ischemic Stroke Involving Both Anterior and Posterior Circulation Treated by Endovascular Revascularization for Acute Basilar Artery Occlusion via Persistent Primitive Trigeminal Artery. ( 27446523 )
2016
25
The challenge of basilar artery occlusion wake-up stroke: too late for intravenous thrombolysis? ( 26960980 )
2016
26
Collateral flow predicts outcome after basilar artery occlusion: The posterior circulation collateral score. ( 27016515 )
2016
27
Thrombectomy using a stent retriever with artificially induced vertebral artery vasospasm in a patient with acute basilar artery occlusion: a case report. ( 26678752 )
2016
28
Mechanical thrombectomy in acute basilar artery occlusion: A safety and efficacy single centre study. ( 26908588 )
2016
29
Intra-arterial revascularization therapy for basilar artery occlusion-a systematic review and analysis. ( 26810313 )
2016
30
A Comparison between Mechanical Thrombectomy and Intra-arterial Fibrinolysis in Acute Basilar Artery Occlusion: Single Center Experiences. ( 27283281 )
2016
31
Basilar artery occlusion in a child treated successfully with mechanical thrombectomy using ADAPT. ( 27075484 )
2016
32
Functional Independence following Endovascular Treatment for Basilar Artery Occlusion despite Extensive Bilateral Pontine Infarcts on Diffusion-Weighted Imaging: Refuting a Self-Fulfilling Prophecy. ( 27781047 )
2016
33
Basilar artery occlusion in a child treated successfully with mechanical thrombectomy using ADAPT. ( 27068722 )
2016
34
Safety and Outcome of Intra-Arterial Treatment for Basilar Artery Occlusion. ( 27532477 )
2016
35
Ruptured aneurysm at the cortical segment of the distal posterior inferior cerebellar artery associated with hemodynamic stress after basilar artery occlusion. ( 28144485 )
2016
36
Where did the clot go? An unusual complication of mechanical thrombectomy caused by malignancy related subclavian steal phenomenon in a patient with acute basilar artery occlusion. ( 27797875 )
2016
37
Neurologic Examination at 24 to 48 Hours Predicts Functional Outcomes in Basilar Artery Occlusion Stroke. ( 27586683 )
2016
38
Revascularization of acute basilar artery occlusion using theA Tigertriever adjustable clot retriever. ( 27511204 )
2016
39
Mechanical thrombectomy with the Solitaire AB stent for treatment of acute basilar artery occlusion: A single-center experience. ( 27312281 )
2016
40
A leap forward in the endovascular management of acute basilar artery occlusion since the appearance of stent retrievers: a single-center comparative study. ( 27257830 )
2016
41
Treatment of a Giant Fusiform Basilar Aneurysm with Partial Intra-Aneurysmal Embolization Combined with Mid-Basilar Artery Occlusion in a Child. ( 27116216 )
2016
42
Endovascular revascularization for basilar artery occlusion. ( 25999990 )
2015
43
Significant period between presentation and diagnosis in basilar artery occlusion: five cases and the lessons learned. ( 25721014 )
2015
44
Predictors of Good Outcome After Stent-Retriever Thrombectomy in Acute Basilar Artery Occlusion. ( 26330448 )
2015
45
Outcomes of endovascular treatment of basilar artery occlusion in the stent retriever era: a systematic review and meta-analysis. ( 26610730 )
2015
46
Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever. ( 26156170 )
2015
47
Recanalization of basilar artery occlusion. ( 26219271 )
2015
48
Mechanical recanalization in basilar artery occlusion: the ENDOSTROKE study. ( 25516154 )
2015
49
Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever. ( 26150626 )
2015
50
Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion. ( 25482105 )
2015

Variations for Basilar Artery Occlusion

Expression for Basilar Artery Occlusion

Search GEO for disease gene expression data for Basilar Artery Occlusion.

Pathways for Basilar Artery Occlusion

Pathways related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

(show all 12)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.81 ARRB1 ARRB2 F2 ITGA2B PLAT PLG
2
Show member pathways
11.86 ARRB1 ARRB2 F2
3
Show member pathways
11.84 F2 PLAT PLG
4 11.72 F2 PLAT PLG
5
Show member pathways
11.68 ARRB1 ARRB2 ITGA2B
6 11.1 ARRB1 ARRB2 FOSB
7 11 F2 PLG
8 10.96 ARRB2 SLC12A3
9 10.85 PLAT PLG
10 10.73 ARRB1 ARRB2 FOSB
11 10.64 F2 PLG
12 10.27 PLAT PLG

GO Terms for Basilar Artery Occlusion

Cellular components related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.32 ARRB1 ARRB2 F2 ITGA2B OXTR PANX1

Biological processes related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.63 ARRB1 ARRB2 F2
2 platelet activation GO:0030168 9.5 ARRB1 ARRB2 F2
3 negative regulation of interleukin-6 production GO:0032715 9.43 ARRB1 ARRB2
4 negative regulation of proteolysis GO:0045861 9.4 F2 PLAT
5 positive regulation of receptor internalization GO:0002092 9.37 ARRB1 ARRB2
6 G-protein coupled receptor internalization GO:0002031 9.26 ARRB1 ARRB2
7 negative regulation of fibrinolysis GO:0051918 9.16 F2 PLG
8 follicle-stimulating hormone signaling pathway GO:0042699 8.96 ARRB1 ARRB2
9 fibrinolysis GO:0042730 8.8 F2 PLAT PLG

Molecular functions related to Basilar Artery Occlusion according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.72 ARRB2 F2 PANX1 PLAT PLG
2 serine-type peptidase activity GO:0008236 9.54 F2 PLAT PLG
3 alpha-1B adrenergic receptor binding GO:0031692 9.26 ARRB1 ARRB2
4 angiotensin receptor binding GO:0031701 9.16 ARRB1 ARRB2
5 alpha-1A adrenergic receptor binding GO:0031691 8.96 ARRB1 ARRB2
6 follicle-stimulating hormone receptor binding GO:0031762 8.62 ARRB1 ARRB2

Sources for Basilar Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....