MCID: BHC003
MIFTS: 60

Behcet Syndrome malady

Categories: Rare diseases, Neuronal diseases, Eye diseases, Cardiovascular diseases, Nephrological diseases, Bone diseases, Skin diseases

Aliases & Classifications for Behcet Syndrome

About this section
Sources:
50OMIM, 11Disease Ontology, 46NIH Rare Diseases, 24Genetics Home Reference, 37MeSH, 66UMLS, 33LifeMap Discovery®, 47NINDS, 13DISEASES, 36MedlinePlus, 48Novoseek, 52Orphanet, 28ICD10, 30ICD9CM, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Behcet Syndrome:

Name: Behcet Syndrome 50 11 46 24 37 66
Behcet's Disease 33 11 46 47 13
Behcet's Syndrome 11 46 24 36
Behcet Disease 46 24 48
Adamantiades-Behcet Disease 11 24
Triple Symptom Complex 11 24
 
Behçet Disease 24 52
Behcet Triple Symptom Complex 24
Old Silk Route Disease 24
Behet's Syndrome 11
Bd 46

Characteristics:

Orphanet epidemiological data:

52
behçet disease:
Inheritance: Multigenic/multifactorial; Prevalence: 1-5/10000 (Japan),>1/1000 (Turkey); Age of onset: Adolescent,Adult,Childhood; Age of death: adult

Classifications:



External Ids:

OMIM50 109650
Disease Ontology11 DOID:13241
ICD1028 M35.2
ICD9CM30 136.1
MeSH37 D001528
NCIt43 C34416
Orphanet52 ORPHA117
ICD10 via Orphanet29 M35.2
MESH via Orphanet38 D001528
UMLS via Orphanet67 C0004943

Summaries for Behcet Syndrome

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NIH Rare Diseases:46 Behcet's disease is a chronic multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes. in some people, the disease also results in arthritis (swollen, painful, stiff joints), skin problems, and inflammation of the digestive tract, brain, and spinal cord. although it can happen at any age, symptoms generally begin when individuals are in their 20s or 30s. the disease is common in japan, turkey and israel, and less common in the united states. the exact cause of behcet's disease is still unknown.  treatment is symptomatic and supportive. experience is evolving with the use of interferon-alpha and with agents which inhibit tumor necrosis factor (tnf) in the treatment of behçet’s disease. behcet's disease is a lifelong disorder that comes and goes. spontaneous remission over time is common for individuals with behçet’s disease but permanent remission of symptoms has not been reported. last updated: 5/25/2015

MalaCards based summary: Behcet Syndrome, also known as behcet's disease, is related to dementia - subcortical and 12p12.1 microdeletion syndrome, and has symptoms including photophobia, meningitis and arthritis. An important gene associated with Behcet Syndrome is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways are Th2 Differentiation Pathway and Immune response_IL-12 signaling pathway. The drug thalidomide has been mentioned in the context of this disorder. Affiliated tissues include eye, skin and spinal cord, and related mouse phenotypes are liver/biliary system and neoplasm.

Disease Ontology:11 A vasculitis that is characterized by an autoimmune mediated inflammation of the blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis.

MedlinePlus:36 Behcet's syndrome is a disease that involves vasculitis, which is inflammation of the blood vessels. it causes problems in many parts of the body. the most common symptoms are sores in the mouth sores on the sex organs other skin sores swelling of parts of the eye pain, swelling and stiffness of the joints more serious problems can include meningitis, blood clots, inflammation of the digestive system and blindness. doctors aren't sure what causes behcet's. it is rare in the united states, but is common in the middle east and asia. it mainly affects people in their 20s and 30s. diagnosing behcet's can take a long time, because symptoms may come and go, and it may take months or even years to have all of the symptoms. there is no cure. treatment focuses on reducing pain and preventing serious problems. most people can control symptoms with treatment. nih: national institute of arthritis and musculoskeletal and skin diseases

NINDS:47 Behcet's disease is a rare, chronic inflammatory disorder. The cause of Behcet's disease is unknown, but current research suggests that both genetic and

Genetics Home Reference:24 Behçet disease is an inflammatory condition that affects many parts of the body. The health problems associated with Behçet disease result from widespread inflammation of blood vessels (vasculitis). This inflammation most commonly affects the mouth, genitals, skin, and eyes.

Wikipedia:69 Behçet\'s disease is a rare immune-mediated small-vessel systemic vasculitis that often presents with... more...

Description from OMIM:50 109650

Related Diseases for Behcet Syndrome

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Diseases related to Behcet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
1dementia - subcortical32.2FAS, IL10, TNF
212p12.1 microdeletion syndrome11.2FAS, IL10, TNF
3pulmonary interstitial glycogenosis11.2IL10, NOD2, TLR4
4benign adult familial myoclonic epilepsy11.2FAS, IL10, STAT4
5piepkorn karp hickok syndrome11.2IL10, TNF
6hernia of ovary and fallopian tube11.2HLA-B, IL10, TNF
7lipodermatosclerosis11.2HLA-B, IL10, TNF
8sensorineural hearing loss11.2HLA-B, IL10, TNF
9hemophagocytic lymphohistiocytosis11.2HLA-B, IL10, TNF
10antigen-peptide-transporter 2 deficiency11.2HLA-B, TLR4, TNF
11senile cataract11.2IL10, MEFV, TNF
12neurotic excoriation11.2IL10, LTA, TNF
13epstein-barr virus hepatitis11.2CRP, HLA-B, TNF
14lemierre's syndrome11.2CRP, MEFV, TNF
15panuveitis11.2IL10, LTA, TNF
16pernicious anemia11.2CRP, IL10, TLR4
17corneal intraepithelial neoplasm11.2HLA-B, IL10, TLR4, TNF
18acquired thrombocytopenia11.2C4A, CRP, MEFV
19gastric dilatation11.2HLA-B, IL10, TNF
20hypospadias11.2IL10, IL12RB2, TNF
21polyarteritis nodosa11.2C4A, CRP, MEFV
226q terminal deletion syndrome11.2IL10, TNF
23chromoblastomycosis11.2C4A, CRP, MEFV
24accessory nerve disease11.2IL10, TLR4, TNF
25meier-gorlin syndrome 311.2MEFV, NOD2, TNF
26primary biliary cirrhosis11.2IL10, LTA, TNF
27orbital periostitis11.2HLA-B, IL10, TNF
28scn8a encephalopathy11.2IL10, RBP3, TNF
29allergic hypersensitivity disease11.2HLA-B, IL10, RBP3, TNF
30bartonellosis11.2IL10, TLR4, TNF
31oral candidiasis11.2CRP, MEFV, TNF
32binocular vision disease11.2IL10, TLR4, TNF
33opportunistic bacterial infectious disease11.1CRP, IL10, MEFV, TNF
34mediastinum seminoma11.1CCR1, IL10, LTA
35pulmonary systemic sclerosis11.1CRP, HLA-B, IL10, TNF
36keratosis11.1IL10, NOD2, TLR4, TNF
37gastroduodenal crohn's disease11.1NOD2, TLR4, TNF
38subendocardial infarction acute myocardial infarction11.1IL10, IL12RB2, TNF
39paraneoplastic polyneuropathy11.1CRP, TLR4, TNF
40retroperitoneal fibrosis11.1IL10, TLR4, TNF
41pyloric stenosis, infantile hypertrophic, 211.1CRP, MEFV, TNF
42neonatal period electroclinical syndrome11.1CRP, IL10, TLR4, TNF
43esophagus melanoma11.1CRP, IL10, TLR4, TNF
44diphtheria11.1CRP, IL10, TLR4, TNF
45mononeuritis of lower limb11.1CRP, IL10, TLR4, TNF
46dentinogenesis imperfecta11.1HLA-B, IL10, TNF
47nephrosclerosis11.1CRP, MEFV, TNF
48lacrimal system cancer11.1FAS, NOD2, TNF
49hemorrhagic fever with renal syndrome11.1CRP, IL10, TLR4, TNF
50psoriasis susceptibility 111.1CRP, HLA-B, NOD2, TNF

Graphical network of the top 20 diseases related to Behcet Syndrome:



Diseases related to behcet syndrome

Symptoms for Behcet Syndrome

About this section

Symptoms by clinical synopsis from OMIM:

109650

Clinical features from OMIM:

109650

Symptoms:

 52 (show all 68)
  • renal insufficiency
  • oral ulcer
  • retinopathy
  • cataract
  • photophobia
  • behavioral abnormality
  • acne
  • keratoconjunctivitis sicca
  • seizures
  • ataxia
  • hemiparesis
  • hyperreflexia
  • arthritis
  • subcutaneous nodule
  • abnormality of the myocardium
  • mitral regurgitation
  • aortic regurgitation
  • pericarditis
  • splenomegaly
  • weight loss
  • anorexia
  • migraine
  • pleuritis
  • hemoptysis
  • pleural effusion
  • gastrointestinal hemorrhage
  • memory impairment
  • encephalitis
  • increased intracranial pressure
  • vasculitis
  • arthralgia
  • myalgia
  • paresthesia
  • venous thrombosis
  • cranial nerve paralysis
  • abnormal pyramidal signs
  • aseptic necrosis
  • recurrent aphthous stomatitis
  • fatigue
  • increased inflammatory response
  • immunologic hypersensitivity
  • myositis
  • optic neuritis
  • retrobulbar optic neuritis
  • gangrene
  • glomerulopathy
  • blindness
  • irritability
  • meningitis
  • gait disturbance
  • confusion
  • myocardial infarction
  • pancreatitis
  • fever
  • nausea and vomiting
  • malabsorption
  • abdominal pain
  • pulmonary infiltrates
  • pulmonary embolism
  • vertigo
  • developmental regression
  • cerebral ischemia
  • lymphadenopathy
  • arterial thrombosis
  • abnormal blistering of the skin
  • endocarditis
  • orchitis
  • papule

HPO human phenotypes related to Behcet Syndrome:

(show all 70)
id Description Frequency HPO Source Accession
1 photophobia hallmark (90%) HP:0000613
2 meningitis hallmark (90%) HP:0001287
3 arthritis hallmark (90%) HP:0001369
4 nausea and vomiting hallmark (90%) HP:0002017
5 migraine hallmark (90%) HP:0002076
6 vasculitis hallmark (90%) HP:0002633
7 myalgia hallmark (90%) HP:0003326
8 abnormality of temperature regulation hallmark (90%) HP:0004370
9 orchitis hallmark (90%) HP:0100796
10 acne typical (50%) HP:0001061
11 gait disturbance typical (50%) HP:0001288
12 abdominal pain typical (50%) HP:0002027
13 gastrointestinal hemorrhage typical (50%) HP:0002239
14 arthralgia typical (50%) HP:0002829
15 reduced consciousness/confusion typical (50%) HP:0004372
16 hemiplegia/hemiparesis typical (50%) HP:0004374
17 thrombophlebitis typical (50%) HP:0004418
18 abnormal blistering of the skin typical (50%) HP:0008066
19 immunologic hypersensitivity typical (50%) HP:0100326
20 renal insufficiency occasional (7.5%) HP:0000083
21 retinopathy occasional (7.5%) HP:0000488
22 visual impairment occasional (7.5%) HP:0000505
23 cataract occasional (7.5%) HP:0000518
24 keratoconjunctivitis sicca occasional (7.5%) HP:0001097
25 seizures occasional (7.5%) HP:0001250
26 polyneuropathy occasional (7.5%) HP:0001271
27 hyperreflexia occasional (7.5%) HP:0001347
28 abnormality of the mitral valve occasional (7.5%) HP:0001633
29 abnormality of the myocardium occasional (7.5%) HP:0001637
30 abnormality of the aortic valve occasional (7.5%) HP:0001646
31 coronary artery disease occasional (7.5%) HP:0001677
32 abnormality of the pericardium occasional (7.5%) HP:0001697
33 pancreatitis occasional (7.5%) HP:0001733
34 splenomegaly occasional (7.5%) HP:0001744
35 weight loss occasional (7.5%) HP:0001824
36 malabsorption occasional (7.5%) HP:0002024
37 anorexia occasional (7.5%) HP:0002039
38 abnormality of the pleura occasional (7.5%) HP:0002103
39 hemoptysis occasional (7.5%) HP:0002105
40 pulmonary infiltrates occasional (7.5%) HP:0002113
41 pulmonary embolism occasional (7.5%) HP:0002204
42 incoordination occasional (7.5%) HP:0002311
43 vertigo occasional (7.5%) HP:0002321
44 memory impairment occasional (7.5%) HP:0002354
45 developmental regression occasional (7.5%) HP:0002376
46 encephalitis occasional (7.5%) HP:0002383
47 increased intracranial pressure occasional (7.5%) HP:0002516
48 cerebral ischemia occasional (7.5%) HP:0002637
49 lymphadenopathy occasional (7.5%) HP:0002716
50 paresthesia occasional (7.5%) HP:0003401
51 abnormality of the endocardium occasional (7.5%) HP:0004306
52 arterial thrombosis occasional (7.5%) HP:0004420
53 cranial nerve paralysis occasional (7.5%) HP:0006824
54 abnormal pyramidal signs occasional (7.5%) HP:0007256
55 aseptic necrosis occasional (7.5%) HP:0010885
56 myositis occasional (7.5%) HP:0100614
57 retrobulbar optic neuritis occasional (7.5%) HP:0100654
58 gangrene occasional (7.5%) HP:0100758
59 glomerulopathy occasional (7.5%) HP:0100820
60 epididymitis HP:0000031
61 oral ulcer HP:0000155
62 irritability HP:0000737
63 iridocyclitis HP:0001094
64 iritis HP:0001101
65 arthritis HP:0001369
66 alopecia areata HP:0002229
67 superficial thrombophlebitis HP:0002638
68 genital ulcers HP:0003249
69 erythema HP:0010783
70 chorioretinitis HP:0012424

UMLS symptoms related to Behcet Syndrome:


chest pain, exanthema, halitosis, oral manifestations, pruritus, snoring, discharge from eye, vasculitic rash

Drugs & Therapeutics for Behcet Syndrome

About this section

Drugs for Behcet Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1PREDNISOLONE ACETATEPhase 4, Phase 3, Phase 21118
2
MethylprednisolonePhase 4, Phase 3, Phase 2111883-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
3
PrednisolonePhase 4, Phase 3, Phase 2111850-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
4
Fluocinolone AcetonidePhase 44067-73-26215
Synonyms:
(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
4b,12-Difluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
6-alpha,9-alpha-Difluoro-16-alpha-hydroxyprednisolone 16,17-acetonide
6.Alpha., 9.alpha.-Difluoro-16.alpha.-h
6.Alpha.,9-Difluoro
6.alpha.,9-Difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
6.alpha.,9.alpha.-Difluoro-16.alpha.-hydroxyprednisolone 16,17-acetonide
6.alpha.-Fluorotriamcinolone acetonide
67-73-2
6a,9a-difluoro-16a-hydroxyprednisolone 16,17-acetonide
6alpha,9-Difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
6alpha,9alpha-Difluoro-11beta,16alpha,17alpha,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
6alpha,9alpha-Difluoro-11beta,16alpha,17alpha,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-Acetonide
6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide
6alpha-Fluorotriamcinolone acetonide
AC-429
AC1L1M1L
AC1Q6ACL
AR-1H0758
Acetonida de fluocinolona
Acetonida de fluocinolona [INN-Spanish]
Acetonide de fluocinolone
Acetonide de fluocinolone [INN-French]
Acetonido de fluocinolona
Acetónida de fluocinolona
Acétonide de fluocinolone
C24H30F2O6
CCRIS 3250
CHEMBL989
CID6215
CPD000058329
Coriphate
Cortiplastol
D01825
DB00591
Derma-smoothe/fs
Dermalar
Dermatin (steroid)
EINECS 200-668-5
F0657
F8880_FLUKA
F8880_SIGMA
FLUOCINOLONE ACETONIDE
FS
Flucinar
Flucinolone
Flucort
Fluocet
Fluocet (TN)
Fluocinolon acetonid
Fluocinolonacetonid
Fluocinolonacetonidum
Fluocinolone 16,17-acetonide
Fluocinolone acetonide (JP15/USP/INN)
Fluocinolone acetonide [DCIT]
Fluocinolone acetonide [USAN:INN:JAN]
 
Fluocinoloni acetonidum
Fluocinoloni acetonidum [INN-Latin]
Fluonid
Fluortriamcinolone Acetonide
Fluotrex
Fluovitif
Flupollon
Fluzon
Fs Shampoo
HMS2090I14
HSDB 3083
Iluvien
Jellin
LS-118443
Localyn
Localyn Syntex
MLS000028545
MLS001076276
Medidur
MolPort-002-528-328
NCGC00021301-04
NCI60_042042
NSC 92339
NSC92339
Neo-Synalar
Omniderm
Percutina
Pregna-1,4-diene-3,20-dione, 6.alpha.,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone (8CI)
Prodermin
RS 1401AT
RS-1401 AT
Radiocin
Retisert
Retisert (TN)
S2470_Selleck
SAM002564208
SMR000058329
STOCK1N-55828
Sinalar
Synalar
Synalar (TN)
Synalar-HP
Synamol
Synandone
Synandrone
Synemol
Synotic
Synsac
Tefunote
UNII-0CD5FD6S2M
WLN: T F5 E5 B666 GO IO RV AHTTTT&J A BF CQ E FVIQ H H OF -A&BHO -B&ACEF
ZINC03977981
component of Neo-Synalar
flucinolone
ydroxyprednisolone 16,17-acetonide
5glucocorticoidsPhase 44756
6
infliximabPhase 3, Phase 1, Phase 2364170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
7interferonsPhase 3, Phase 22112
8
ThalidomidePhase 3, Phase 2106050-35-15426
Synonyms:
( inverted question mark)-Thalidomide
(+)-Thalidomide
(+-)-N-(2,6-dioxo-3-Piperidyl)phthalimide
(+-)-Thalidomide
(+/-)-THALIDOMIDE
(?)-Thalidomide
(±)-N-(2,6-dioxo-3-piperidyl)phthalimide
(±)-thalidomide
.alpha.-(N-Phthalimido)glutarimide
.alpha.-N-Phthalylglutaramide
.alpha.-Phthalimidoglutarimide
1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline
14088-68-7
2,6-Dioxo-3-phthalimidopiperidine
2,6-dioxo-3-phthalimidopiperidine
3-Phthalimidoglutarimide
50-35-1
731-40-8
AB00052362
AC-917
AC1L1KBZ
AC1Q6FJA
AI3-50606
Algosediv
Asidon 3
Asmadion
Asmaval
BPBio1_000159
BRD-A93255169-001-06-9
BRN 0030233
BSPBio_000143
BSPBio_001156
BSPBio_003330
Bio1_000387
Bio1_000876
Bio1_001365
Bio2_000418
Bio2_000898
Bonbrain
Bonbrrin
C07910
C13H10N2O4
CCRIS 8148
CHEBI:105028
CHEMBL468
CID5426
CPD000058524
Calmore
Calmorex
Celgene Brand of Thalidomide
Contergan
Corronarobetin
D00754
D013792
DB01041
Distaval
Distaxal
Distoval
DivK1c_000051
E-217
EINECS 200-031-1
ENMD 0995
EU-0101224
Ectiluran
Enterosediv
Gastrinide
Glupan
Glutanon
Grippex
HMS1362J17
HMS1568H05
HMS1792J17
HMS1922E12
HMS1990J17
HMS2090O05
HMS2093G15
HMS500C13
HSDB 3586
Hippuzon
I06-0197
IDI1_000051
IDI1_002173
IN1061
Imida-Lab
Imida-lab
Imidan
Imidan (peyta)
Imidene
Isomin
K 17
K-17
KBio1_000051
KBio2_000496
KBio2_002322
KBio2_003064
KBio2_004890
KBio2_005632
KBio2_007458
KBio3_000911
KBio3_000912
KBio3_002550
KBio3_002802
KBioGR_000496
KBioGR_001474
KBioGR_002322
KBioSS_000496
KBioSS_002324
Kedavon
Kevadon
LS-109463
LS-140
Lopac0_001224
Lulamin
MLS000069353
MolPort-003-665-582
N-(2,6-Dioxo-3-piperidyl)phthalimide
N-(2,6-dioxo-3-piperidyl)phthalimide
N-Phthalimidoglutamic acid imide
N-Phthaloylglutamimide
N-Phthalyl-glutaminsaeure-imid
N-Phthalyl-glutaminsaeure-imid [German]
N-Phthalylglutamic acid imide
NCGC00015989-03
NCGC00015989-13
NCGC00024708-02
 
NCGC00024708-03
NCGC00024708-04
NCGC00024708-05
NCGC00024708-06
NCGC00024708-07
NCGC00024708-08
NCGC00024708-09
NCI60_023904
NCIOpen2_003188
NINDS_000051
NSC 527179
NSC-66847
NSC527179
NSC66847
NSC91729
NSC91730
Neaufatin
Neo
Neosedyn
Neosydyn
Nerosedyn
Neufatin
Neurodyn
Neurosedin
Neurosedym
Neurosedyn
Nevrodyn
Nibrol
Noctosediv
Noxodyn
Pangul
Pantosediv
Poly-Giron
Polygripan
Predni-Sediv
Prestwick0_000192
Prestwick1_000192
Prestwick2_000192
Prestwick3_000192
Prestwick_463
Pro-Bam M
Pro-ban M
Profarmil
Psycholiquid
Psychotablets
Quetimid
Quietoplex
S1193_Selleck
SAM002564245
SMR000058524
SPBio_000893
SPBio_002064
SPECTRUM1503607
ST51039042
Sandormin
Sedalis
Sedalis sedi-lab
Sedimide
Sedin
Sedisperil
Sedoval
Shin-naito S
Shinnibrol
Sleepan
Slipro
Softenil
Softenon
Spectrum2_000707
Spectrum3_001715
Spectrum4_001087
Spectrum5_001791
Synovir
T144_SIGMA
T150_SIGMA
T151_SIGMA
THALIDOMIDE (AIDS INITIATIVE)
Talargan
Talidomida
Talidomida [INN-Spanish]
Talidomide
Talidomide [DCIT]
Talimol
Talismol
Talizer
Telagan
Telargan
Telargean
Tensival
Thaled
Thaled (TN)
Thalidomide
Thalidomide (+ and -)
Thalidomide (JAN/USP/INN)
Thalidomide (soluble form)
Thalidomide Celgene
Thalidomide Pharmion
Thalidomide [USAN:INN:BAN]
Thalidomidum
Thalidomidum [INN-Latin]
Thalidomine USP26
Thalin
Thalinette
Thalomid
Thalomid (TM)
Thalomid (TN)
Thalomid, Thalidomide
Thalomide
Theophilcholine
UNII-4Z8R6ORS6L
UPCMLD-DP139
UPCMLD-DP139:001
Valgis
Valgraine
WLN: T56 BVNVJ C- DT6VMVTJ
WLN: T56 BVNVJ C- DT6VMVTJ -D
WLN: T56 BVNVJ C- DT6VMVTJ -L
Yodomin
alpha-(N-Phthalimido)glutarimide
alpha-N-Phthalylglutaramide
alpha-Phthalimidoglutarimide
alpha-phthalimidoglutarimide
cMAP_000022
thalidomide
α-(N-phthalimido)glutarimide
α-N-phthalylglutaramide
α-phthalimidoglutarimide
9
ApremilastPhase 3, Phase 260608141-41-911561674
Synonyms:
Apremilast
Apremilast (USAN)
Apremilastum
Aprémilast
CC-10004
 
CHEBI:558773
CHEMBL514800
CID11561674
D08860
N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
10
EtanerceptPhase 3391185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
11
adalimumabPhase 3466331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
12
PregabalinPhase 3348148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
13
MiconazolePhase 3357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
14calcium channel blockersPhase 31889
15FACTOR VIIIPhase 3282
16
MethotrexatePhase 214961959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
17
ColchicinePhase 210664-86-86167, 2833
Synonyms:
(S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
30512-31-3
5843-86-7
64-86-8
7-alpha-H-Colchicine
7.alpha.H-Colchicine
7alphaH-Colchicine
AC1L1LXO
ACon1_000353
AI3-31149
AKOS001582887
BB_NC-0737
BPBio1_000535
BRD-K00259736-001-06-5
BSPBio_000485
BSPBio_002083
Benzo(a)heptalen-9(5H)-one
C 9754
C07592
C22H25NO6
C3915_SIGMA
C9754_SIGMA
CCRIS 691
CHEBI:27882
CHEMBL107
CID6167
CPD-9785
Colchicin
Colchicin [German]
Colchicina
Colchicina [Italian]
Colchicine (JP15/USP)
Colchicine (TN)
Colchicine [JAN]
Colchicine, (+-)-Isomer
Colchicine, (R)-Isomer
Colchicine, Colchicum autumnale
Colchicinum
Colchineos
Colchisol
Colchysat
Colcin
Colcrys
Colsaloid
Colstat
Condylon
D003078
D00570
DB01394
DB08117
DivK1c_000753
EINECS 200-598-5
EU-0100310
Goutnil
HMS1569I07
HMS1920A08
HMS2091G16
HMS502F15
HSDB 3044
IDI1_000753
KBio1_000753
KBio2_001322
KBio2_003890
 
KBio2_006458
KBio3_001303
KBioGR_000856
KBioSS_001322
Kolkicin
LOC
LS-279
Lopac0_000310
MEGxp0_001879
MLS001055448
MLS001055448-02
MLS001304089
MLS002153786
MPC-004
MolPort-001-742-594
N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)- acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-acetamide
N-Acetyl trimethylcolchicinic acid methylether
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
NCGC00025125-01
NCGC00025125-02
NCGC00025125-03
NCGC00025125-04
NCGC00025125-05
NCGC00025125-06
NCGC00025125-07
NCGC00025125-11
NCGC00169157-01
NCGC00169157-02
NCGC00169157-03
NCI60_041659
NChemBio.2007.10-comp20
NINDS_000753
NSC 757
NSC757
Prestwick0_000363
Prestwick1_000363
Prestwick2_000363
Prestwick3_000363
Prestwick_695
S2284_Selleck
SDCCGMLS-0066633.P001
SMR000058323
SPBio_000289
SPBio_002406
SPECTRUM1500205
Spectrum2_000075
Spectrum3_000362
Spectrum4_000298
Spectrum5_000787
Spectrum_000842
Tocris-1364
UNII-SML2Y3J35T
UPCMLD-DP065
UPCMLD-DP065:001
WLN: L B677 MV&T&J CO1 DO1 EO1 JMV1 NO1
ZINC00621853
binds to tubulin
colchicine
inhibits microtubular assembly
nchembio853-comp2
spindle poison
18
CyclophosphamidePhase 2275650-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
19
rituximabPhase 21611174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
20
DaclizumabPhase 298152923-56-3
Synonyms:
Anti-IL-2
 
Humanized antiCD25
Ig gamma-1 chain C region
21INTERLEUKIN-2Phase 2537
22
AzathioprinePhase 2158446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
HMS1920E17
 
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
23
AldesleukinPhase 239185898-30-2, 110942-02-4
Synonyms:
125-L-serine-2-133-interleukin 2 (human reduced)
 
Interleukin-2 aldesleukin
Interleukin-2(2-133),125-ser
Recombinant interleukin-2 human
24
UstekinumabPhase 279815610-63-0
Synonyms:
CNTO-1275
 
Stelara
Ustekinumab
25
AltretaminePhase 158645-05-62123
Synonyms:
2,4, 6-Tris(dimethylamino)-1,3,5-triazine
2,4,6-Tris(dimethylami
2,4,6-Tris(dimethylamino)-1,3,5-triazine
2,4,6-Tris(dimethylamino)-S-triazine
2,4,6-Tris(dimethylamino)-s-triazine
2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
549835_ALDRICH
645-05-6
A 8723
A0567/0026158
A8723_SIGMA
AB00052308
AC-12006
AC1L1CYX
AI3-50852
AKOS001729401
Altretamin
Altretamina
Altretamina [INN-Spanish]
Altretamine (USP/INN)
Altretamine Bellon Brand
Altretamine Chiesi Brand
Altretamine Wassermann Brand
Altretamine [USAN:INN:BAN]
Altretaminum
Altretaminum [INN-Latin]
Altrétamine
BPBio1_001004
BRD-K67043667-001-04-1
BRN 0195058
BSPBio_000912
Bellon Brand of Altretamine
C9H18N6
CAS-654-05-6
CCRIS 5492
CHEBI:24564
CHEMBL1455
CID2123
CPD000058181
ChemDiv2_005185
Chiesi Brand of Altretamine
D006585
D02841
DB00488
DivK1c_000772
EINECS 211-428-4
ENT 50852
EU-0100083
FT-0083576
HEXAMETHYLMELAMINE
HMM
HMS1383L15
HMS1570N14
HMS1922C05
HMS2090G17
HMS2092H16
HMS502G14
HSDB 7559
HTM
HXM
Hemel
Hexalen
Hexalen (TN)
Hexalen, Altretamine
 
Hexamethylmelamine
Hexastat
Hexinawas
I06-0604
IDI1_000772
IDI1_003900
InChI=1/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H
KB-913
KBio1_000772
KBio2_001788
KBio2_004356
KBio2_006924
KBio3_002042
KBioGR_001388
KBioSS_001788
LS-1549
Lopac-A-8723
Lopac0_000083
MGI Pharma Brand of Altretamine
MLS000069621
MLS001076123
MolPort-002-111-210
N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine
NC 195
NCGC00015100-01
NCGC00015100-02
NCGC00015100-03
NCGC00015100-06
NCGC00015100-11
NCGC00021216-03
NCGC00021216-04
NCGC00021216-05
NCGC00021216-06
NCGC00021216-07
NCI-C50259
NCI60_000871
NINDS_000772
NSC 13875
NSC-13875
NSC13875
N~2~,N~2~,N~4~,N~4~,N~6~,N~6~-Hexamethyl-1,3,5-triazine-2,4,6-triamine
Prestwick0_000946
Prestwick1_000946
Prestwick2_000946
Prestwick3_000946
Rhone Poulenc Rorer Brand of Altretamine
Rhone-Poulenc Rorer Brand of Altretamine
S1278_Selleck
SAM002564241
SMR000058181
SPBio_000754
SPBio_003071
SPECTRUM1503065
ST086739
STK749184
Spectrum2_000907
Spectrum3_000951
Spectrum4_001064
Spectrum5_001092
Spectrum_001308
UNII-Q8BIH59O7H
WLN: T6N CN ENJ BN1&1 DN1&1 FN1&1
Wassermann Brand of Altretamine
ZINC00000905
altretamine
no)-s-triazine
26insulinPhase 14401
27
Abatacept188332348-12-610237
Synonyms:
CTLA4-Ig
 
CTLA4-IgG4m
CTLA4Ig
CTLA4IgG4m
28FolateNutraceutical4143
29
Folic AcidNutraceutical414359-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10

Interventional clinical trials:

(show top 50)    (show all 64)
idNameStatusNCT IDPhase
1Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's DiseaseRecruitingNCT00720928Phase 4
2The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's DiseaseRecruitingNCT01306955Phase 4
3Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein LevelsTerminatedNCT00578578Phase 4
4Clinical Study of TA-650 in Patients With Behcet's Disease (BD) With Special LesionsCompletedNCT01532570Phase 3
5A Study of Adalimumab in Japanese Subjects With Intestinal Behçet's DiseaseCompletedNCT01243671Phase 3
6Phase III Study in Refractory Behcet's DiseaseCompletedNCT00995709Phase 3
7Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque PsoriasisCompletedNCT01690299Phase 3
8A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behcet's DiseaseRecruitingNCT02307513Phase 3
9A Study to Evaluate Efficacy and Safety of Infliximab in Participant With Moderate-to-Severe Refractory Intestinal Behcet's DiseaseRecruitingNCT02505568Phase 3
10Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB)RecruitingNCT00167583Phase 3
11Efficacy of Humira in Behcet Patients With ArthritisRecruitingNCT01497717Phase 3
12A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-ClonRecruitingNCT01463306Phase 3
13A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.RecruitingNCT02072824Phase 3
14A Study of the Efficacy and Safety of Pregabalin as Add-On Therapy for Partial Onset Seizures in Children Ages 4-16 YearsActive, not recruitingNCT01389596Phase 3
15Study Evaluating Prophylaxis Treatment & Characterizing Efficacy, Safety, & PK Of B-Domain Deleted Recombinant FVIIIActive, not recruitingNCT00543439Phase 3
16Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease UveitisTerminatedNCT02258867Phase 3
17Efficacy of Gevokizumab in the Treatment of Patients With Behçet's Disease Uveitis (EYEGUARD™-B)TerminatedNCT01965145Phase 3
18Long-term Safety of Gevokizumab in the Treatment of Patients With Chronic Non-infectious Uveitis (EYEGUARD-X)TerminatedNCT02375685Phase 3
19An Open-label, Rollover Study Providing Continued Dosing of Gevokizumab in Order to Assess Long-term Gevokizumab Safety DataTerminatedNCT02258854Phase 3
2038 Week Extension Study to CAIN457C2303TerminatedNCT01093846Phase 3
21A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet DiseaseCompletedNCT00866359Phase 2
22Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's DiseaseCompletedNCT00700297Phase 2
23Low Dose Interferon Alpha Treatment for Oral Ulcers of Behcet's DiseaseCompletedNCT00483184Phase 2
24HAT in Eye Complications of Behcet's DiseaseCompletedNCT00001865Phase 2
25Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's DiseaseCompletedNCT00664599Phase 2
26Intravitreal Infliximab in Refractory Uveitis in Behcet's Disease: A Safety and Efficacy Clinical StudyCompletedNCT02620618Phase 1, Phase 2
27Anakinra for Behcet s DiseaseCompletedNCT01441076Phase 1, Phase 2
28Ilaris (Canakinumab) in the Schnitzler SyndromeCompletedNCT01245127Phase 2
29Efficacy and Safety Study of Two Doses of Apremilast (CC-10004) In Japanese Subjects With Moderate-To-Severe Plaque-Type PsoriasisCompletedNCT01988103Phase 2
30Safety and Efficacy of AIN457 in Noninfectious UveitisCompletedNCT00685399Phase 2
311 Year Canakinumab Treatment in Behcet's Disease Patients With Neurologic or Vascular InvolvementRecruitingNCT02756650Phase 2
32Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory DiseasesRecruitingNCT01988506Phase 2
33Efficacy and Safety of Ustekinumab, a Human Monoclonal Anti-IL-12/IL-23 Antibody, in Patients With Behçet DiseaseNot yet recruitingNCT02648581Phase 2
34A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's DiseaseWithdrawnNCT01211977Phase 1, Phase 2
35Stem Cell Transplantation for the Treatment of Knee OsteoarthritisEnrolling by invitationNCT00550524Phase 1
36Stem Cell Transplantation in Ocular Lesions of Behcet's DiseaseTerminatedNCT00550498Phase 1
37Hematopoietic Stem Cell Support in VasculitisTerminatedNCT00278512Phase 1
38Psychological Symptoms in Patients With Behcet's Disease by SCL90-RCompletedNCT00699985
39Behçet's Disease and Eosinophil Cationic ProteinCompletedNCT01584778
40MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASECompletedNCT01780363
41The Relationship Between Serum Levels of Angiogenin, bFGF, VEGF and Ocular Involvement in Patients With Behçet's DiseaseCompletedNCT01720628
42Educational Needs of Patients With Systemic VasculitisCompletedNCT02190929
43Reproductive Health in Men and Women With VasculitisCompletedNCT02176070
44Vasculitis Illness Perception (VIP) StudyCompletedNCT02190916
45Impact of Vasculitis on Employment and IncomeCompletedNCT02476292
46Uveitis Gene-Expression ProfilingCompletedNCT00874471
47Biological Markers in Retinal VasculitisCompletedNCT00050492
48Evaluation and Treatment of Patients With Inflammatory Eye DiseasesCompletedNCT00006188
49Nutritional Status of Cerebral Palsy Patients in TurkeyCompletedNCT02589704
50Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's DiseaseRecruitingNCT00931957

Search NIH Clinical Center for Behcet Syndrome

Inferred drug relations via UMLS66/NDF-RT44:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Behcet Syndrome cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Behcet Syndrome:
Bone marrow-derived stem cells for treatment of ocular lesions Behcet's disease
Embryonic/Adult Cultured Cells Related to Behcet Syndrome:
Bone marrow-derived stem cells, PMIDs: 21199472, 23773637


Cochrane evidence based reviews: behcet syndrome

Genetic Tests for Behcet Syndrome

About this section

Anatomical Context for Behcet Syndrome

About this section

MalaCards organs/tissues related to Behcet Syndrome:

34
Eye, Skin, Spinal cord, Brain, Bone, Neutrophil, T cells

Animal Models for Behcet Syndrome or affiliated genes

About this section

MGI Mouse Phenotypes related to Behcet Syndrome:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537010.6CCR1, FAS, IL10, IL12RB2, LTA, MEFV
2MP:000200610.6FAS, IL10, IL12A, IL12RB2, IL23R, TLR4
3MP:000538810.5CCR1, FAS, IL10, IL12A, LTA, TLR4
4MP:000538110.5CCR1, FAS, IL10, IL12RB2, IL23R, NOD2
5MP:000538710.2CCR1, CRP, ERAP1, FAS, IL10, IL12A
6MP:000539710.2CCR1, ERAP1, FAS, IL10, IL12A, IL12RB2
7MP:000537610.1CCR1, CRP, FAS, IL10, IL12A, IL12RB2

Publications for Behcet Syndrome

About this section

Articles related to Behcet Syndrome:

idTitleAuthorsYear
1
Delayed Vasospasm after Aneurysmal Subarachnoid Hemorrhage in Behcet Syndrome. (27114963)
2016
2
Clinical and Ultrasonographic Evaluation of Lower-extremity Vein Thrombosis in Behcet Syndrome: An Observational Study. (26554787)
2015
3
JAK2 (V617F) mutation is not associated with thrombosis in Behcet syndrome. (22203033)
2012
4
Summary of workshop on recurrent aphthous stomatitis and Behcet syndrome. (281401)
1978

Variations for Behcet Syndrome

About this section

Copy number variations for Behcet Syndrome from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1241985868351706856724Copy numberDEFA1Behcet''s disease

Expression for genes affiliated with Behcet Syndrome

About this section
Search GEO for disease gene expression data for Behcet Syndrome.

Pathways for genes affiliated with Behcet Syndrome

About this section

Pathways related to Behcet Syndrome according to GeneCards Suite gene sharing:

(show all 32)
idSuper pathwaysScoreTop Affiliating Genes
110.3IL10, IL12RB2, STAT4
2
Show member pathways
10.3IL12A, IL12RB2, STAT4
310.3IL10, TLR4, TNF
410.3IL10, IL12A, TNF
510.3IL12A, TLR4, TNF
610.3IL12A, TLR4, TNF
710.3LTA, TLR4, TNF
810.3LTA, TLR4, TNF
910.3IL10, IL12A, IL12RB2, STAT4
10
Show member pathways
10.3IL10, IL23R, STAT4, TNF
11
Show member pathways
10.3IL10, IL12A, TLR4, TNF
1210.3IL10, IL12A, TLR4, TNF
1310.3IL10, IL12A, TLR4, TNF
14
Show member pathways
10.3FAS, IL10, IL12A, TNF
1510.3FAS, IL10, IL12A, TNF
1610.3IL10, LTA, TLR4, TNF
1710.3IL10, IL12A, LTA, TNF
18
Show member pathways
10.2IL10, IL12A, IL12RB2, IL23R, STAT4
1910.2FAS, LTA, NOD2, TNF
20
Show member pathways
10.2HLA-B, IL10, IL12A, LTA, TNF
2110.2IL10, IL12A, NOD2, TLR4, TNF
2210.2C4A, IL10, IL12A, TLR4, TNF
23
Show member pathways
10.2FAS, IL12A, LTA, TLR4, TNF
2410.2IL10, IL12A, IL12RB2, IL23R, LTA, TNF
25
Show member pathways
10.2FAS, IL10, IL12A, STAT4, TLR4, TNF
26
Show member pathways
10.1FAS, HLA-B, IL12A, LTA, TLR4, TNF
27
Show member pathways
10.1IL10, IL12A, IL12RB2, IL23R, LTA, STAT4
28
Show member pathways
10.1CCR1, FAS, IL10, IL12A, IL12RB2, IL23R
29
Show member pathways
10.0CCR1, FAS, IL10, IL12A, IL12RB2, IL23R
30
Show member pathways
10.0CCR1, FAS, IL10, IL12A, IL12RB2, IL23R
31
Show member pathways
9.9C4A, CRP, ERAP1, HLA-B, IL12A, IL12RB2
32
Show member pathways
9.8C4A, FAS, HLA-B, IL10, IL12A, IL12RB2

GO Terms for genes affiliated with Behcet Syndrome

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Cellular components related to Behcet Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:000989710.4CCR1, FAS, IL12RB2, TLR4, TNF
2extracellular spaceGO:000561510.0C4A, CRP, ERAP1, FAS, IL10, IL12A

Biological processes related to Behcet Syndrome according to GeneCards Suite gene sharing:

(show all 36)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of tyrosine phosphorylation of Stat4 proteinGO:004252011.1IL12A, IL23R
2positive regulation of NK T cell activationGO:005113511.1IL12A, IL23R
3positive regulation of interleukin-17 productionGO:003274011.1IL23R, NOD2
4receptor biosynthetic processGO:003280011.0IL10, TNF
5negative regulation of cytokine secretion involved in immune responseGO:000274011.0IL10, TNF
6interferon-gamma productionGO:003260911.0IL12RB2, TLR4
7negative regulation of interleukin-17 productionGO:003270011.0IL12A, TLR4
8necroptotic signaling pathwayGO:009752711.0FAS, TNF
9positive regulation of T cell mediated cytotoxicityGO:000191611.0IL12A, IL23R
10positive regulation of lymphocyte proliferationGO:005067111.0IL12A, TLR4
11positive regulation of chronic inflammatory response to antigenic stimulusGO:000287611.0LTA, TNF
12positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292511.0LTA, TNF
13positive regulation of interleukin-8 biosynthetic processGO:004541611.0TLR4, TNF
14negative regulation of interleukin-12 productionGO:003269511.0IL10, MEFV
15positive regulation of MHC class II biosynthetic processGO:004534811.0IL10, TLR4
16positive regulation of nitric-oxide synthase biosynthetic processGO:005177010.9NOD2, TLR4
17positive regulation of NIK/NF-kappaB signalingGO:190122410.9NOD2, TNF
18negative regulation of lipid storageGO:001088810.9CRP, TNF
19negative regulation of interleukin-6 productionGO:003271510.9IL10, TLR4, TNF
20response to glucocorticoidGO:005138410.9FAS, IL10, TNF
21extrinsic apoptotic signaling pathwayGO:009719110.9FAS, IL12A, TNF
22positive regulation of osteoclast differentiationGO:004567210.9CCR1, IL23R, TNF
23obsolete transformed cell apoptotic processGO:000692710.9FAS, TNF
24negative regulation of growth of symbiont in hostGO:004413010.9IL10, LTA, TNF
25positive regulation of JNK cascadeGO:004633010.8NOD2, TLR4, TNF
26cellular response to lipopolysaccharideGO:007122210.8IL10, IL12A, TLR4, TNF
27positive regulation of interferon-gamma productionGO:003272910.7IL12A, IL12RB2, IL23R, LTA, TLR4, TNF
28defense response to bacteriumGO:004274210.6IL10, NOD2, TLR4, TNF
29positive regulation of interleukin-8 productionGO:003275710.5NOD2, TLR4, TNF
30positive regulation of interleukin-6 productionGO:003275510.5NOD2, TLR4, TNF
31apoptotic signaling pathwayGO:009719010.3FAS, TLR4, TNF
32positive regulation of ERK1 and ERK2 cascadeGO:007037410.3CCR1, NOD2, TLR4, TNF
33inflammatory responseGO:000695410.2C4A, CCR1, CRP, FAS, IL10, IL23R
34response to lipopolysaccharideGO:003249610.2FAS, IL10, IL12A, IL12RB2, IL23R, LTA
35defense response to Gram-positive bacteriumGO:005083010.1CRP, IL12A, LTA, TNF
36immune responseGO:00069559.9CCR1, FAS, IL10, IL12A, TLR4

Molecular functions related to Behcet Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interleukin-12 receptor bindingGO:000514310.9IL12A, IL23R
2tumor necrosis factor receptor bindingGO:000516410.6ERAP1, LTA, TNF
3complement component C1q bindingGO:000184910.4C4A, CRP
4cytokine activityGO:000512510.3IL10, IL12A, LTA, TNF

Sources for Behcet Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet