MCID: BHC002
MIFTS: 69

Behcet's Disease malady

Categories: Rare diseases, Neuronal diseases, Eye diseases, Cardiovascular diseases, Nephrological diseases, Bone diseases, Skin diseases

Aliases & Classifications for Behcet's Disease

About this section
Sources:
32LifeMap Discovery®, 10Disease Ontology, 45NIH Rare Diseases, 46NINDS, 12DISEASES, 23Genetics Home Reference, 36MeSH, 65UMLS, 35MedlinePlus, 47Novoseek, 51Orphanet, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Behcet's Disease:

Name: Behcet's Disease 32 10 45 46 12
Behcet Syndrome 10 45 23 36 65
Behcet's Syndrome 10 45 23 35
Behcet Disease 45 23 47
Adamantiades-Behcet Disease 10 23
Triple Symptom Complex 10 23
 
Behçet Disease 23 51
Behcet Triple Symptom Complex 23
Old Silk Route Disease 23
Behet's Syndrome 10
Bd 45

Characteristics:

Orphanet epidemiological data:

51
behçet disease:
Inheritance: Multigenic/multifactorial; Prevalence: 1-5/10000 (Japan),>1/1000 (Turkey); Age of onset: Adolescent,Adult,Childhood; Age of death: adult

Classifications:



External Ids:

Disease Ontology10 DOID:13241
ICD1027 M35.2
ICD9CM29 136.1
MeSH36 D001528
NCIt42 C34416
Orphanet51 117
ICD10 via Orphanet28 M35.2
MESH via Orphanet37 D001528
UMLS via Orphanet66 C0004943
UMLS65 C0004943

Summaries for Behcet's Disease

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NIH Rare Diseases:45 Behcet's disease is a chronic multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes. in some people, the disease also results in arthritis (swollen, painful, stiff joints), skin problems, and inflammation of the digestive tract, brain, and spinal cord. although it can happen at any age, symptoms generally begin when individuals are in their 20s or 30s. the disease is common in japan, turkey and israel, and less common in the united states. the exact cause of behcet's disease is still unknown.  treatment is symptomatic and supportive. experience is evolving with the use of interferon-alpha and with agents which inhibit tumor necrosis factor (tnf) in the treatment of behçet’s disease. behcet's disease is a lifelong disorder that comes and goes. spontaneous remission over time is common for individuals with behçet’s disease but permanent remission of symptoms has not been reported. last updated: 5/25/2015

MalaCards based summary: Behcet's Disease, also known as behcet syndrome, is related to diamond-blackfan anemia 1 and bd syndrome, and has symptoms including orchitis, abnormality of temperature regulation and myalgia. An important gene associated with Behcet's Disease is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways are Jak/STAT Signaling Pathway and Th2 Differentiation Pathway. The drug thalidomide has been mentioned in the context of this disorder. Affiliated tissues include eye, skin and spinal cord, and related mouse phenotypes are liver/biliary system and digestive/alimentary.

Disease Ontology:10 A vasculitis that is characterized by an autoimmune mediated inflammation of the blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis.

Genetics Home Reference:23 Behçet disease is an inflammatory condition that affects many parts of the body. The health problems associated with Behçet disease result from widespread inflammation of blood vessels (vasculitis). This inflammation most commonly affects the mouth, genitals, skin, and eyes.

MedlinePlus:35 Behcet's syndrome is a disease that involves vasculitis, which is inflammation of the blood vessels. it causes problems in many parts of the body. the most common symptoms are sores in the mouth sores on the sex organs other skin sores swelling of parts of the eye pain, swelling and stiffness of the joints more serious problems can include meningitis, blood clots, inflammation of the digestive system and blindness. doctors aren't sure what causes behcet's. it is rare in the united states, but is common in the middle east and asia. it mainly affects people in their 20s and 30s. diagnosing behcet's can take a long time, because symptoms may come and go, and it may take months or even years to have all of the symptoms. there is no cure. treatment focuses on reducing pain and preventing serious problems. most people can control symptoms with treatment. nih: national institute of arthritis and musculoskeletal and skin diseases

NINDS:46 Behcet's disease is a rare, chronic inflammatory disorder. The cause of Behcet's disease is unknown, but current research suggests that both genetic and

Wikipedia:68 Behçet\'s disease or Behçet disease (/bɛˈtʃɛt/), sometimes called Behçet\'s syndrome, Morbus... more...

Related Diseases for Behcet's Disease

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Diseases related to Behcet's Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 132)
idRelated DiseaseScoreTop Affiliating Genes
1diamond-blackfan anemia 132.9CRP, IL10, TNF
2bd syndrome12.1
3anti-hla hyperimmunization11.2HLA-B, TLR4, TNF
4monocular exotropia11.2HLA-B, MICA, TNF
5rhinoscleroma11.2CRP, MEFV, TNF
6blue color blindness11.2CRP, HLA-B, MEFV, TNF
7ureteral disease11.2CRP, MEFV, TNF
8acneiform dermatitis11.2HLA-B, HLA-C, TNF
9alcohol-induced mental disorder11.2CRP, HLA-B, MICA, TNF
10hypercementosis11.2HLA-B, IL10, TNF
11punctate palmoplantar keratoderma type 211.2IL10, TNF
12cytoplasmic body myopathy11.2HLA-B, IL10, TNF
13familial mediterranean fever, ad11.2CRP, MEFV, TNF
14tuberculoid leprosy11.2CRP, MEFV, TNF
15hodgkin's granuloma11.2CRP, HLA-B, MEFV, TNF
16placental abruption11.2HLA-B, IL10, MEFV, TNF
17inflammatory spondylopathy11.2HLA-B, LTA, TNF
18achalasia11.2IL10, LTA, TNF
19porphyria11.2CRP, LTA, TLR4, TNF
20idiopathic spinal cord herniation11.1IL10, TLR4, TNF
21methylmalonic acidemia11.1HLA-B, IL10, TLR4, TNF
22cholera11.1HLA-B, IL10, TNF
23precursor b lymphoblastic lymphoma/leukemia11.1IL10, LTA, TNF
24tracheal stenosis11.1HLA-B, IL10, TNF
25early-onset, autosomal dominant alzheimer disease11.1IL10, SAG, TNF
26kernicterus due to isoimmunization11.1HLA-B, IL10, SAG, TNF
27primary progressive freezing gait11.1IL10, TNF
28peritoneal mesothelioma11.1CRP, MEFV, TNF
29microsomia hemifacial radial defects11.1HLA-B, TNF
30funisitis11.1CRP, IL10, TLR4, TNF
31meningitis11.1CRP, IL10, TLR4, TNF
32trachoma11.1IL10, TLR4, TNF
33commensal bacterial infectious disease11.1CRP, IL10, TLR4, TNF
34limited scleroderma11.1CRP, HLA-B, IL10, TNF
35multiple symmetric lipomatosis11.1IL10, LTA, TLR4, TNF
36constant exophthalmos11.1CRP, IL10, TNF
37dentin dysplasia11.1HLA-B, IL10, TNF
38diffuse scleroderma11.1CRP, IL10, TLR4, TNF
39acute gonococcal epididymo-orchitis11.1IL10, TLR4, TNF
40squamous cell papilloma11.1HLA-B, HLA-C, LTA
41hemolytic anemia11.1HLA-B, HLA-C, IL10, TNF
42fatty liver disease11.1CRP, HLA-B, TNF
43lateral sclerosis11.1CRP, IL10, TNF
44moderately severe hemophilia a11.1F5, IL10, TNF
45chronic cystitis11.1CRP, TLR4, TNF
46acute orbital inflammation11.1HLA-B, HLA-C, IL10, TNF
47necatoriasis11.1IL10, TLR4, TNF
48leech infestation11.1CRP, IL10, MEFV, TLR4, TNF
49acute zonal occult outer retinopathy11.1F5, LTA, TNF
50keratinizing squamous cell carcinoma11.1CRP, IL10, TLR4, TNF

Graphical network of the top 20 diseases related to Behcet's Disease:



Diseases related to behcet's disease

Symptoms for Behcet's Disease

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Symptoms:

 51 (show all 67)
  • photophobia
  • follicular/erythematous/edematous papules/milium
  • enanthema/aphtosa/aphta/leukoplakia
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • vascularitis/vasculitides/arteritis
  • testes inflammation/orchitis
  • facial pain/cephalalgia/migraine
  • meningitis/meningeal syndrome
  • myalgia/muscular pain
  • arthritis/synovitis/synovial proliferation
  • fever/chilling
  • asthenia/fatigue/weakness
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • acne/acnea
  • acute abdominal pain/colic
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • venous thrombosis/phlebitis/thrombophlebitis
  • abnormal gait
  • hemiplegia/diplegia/hemiparesia/limb palsy
  • obnubilation/coma/lethargia/desorientation
  • articular/joint pain/arthralgia
  • severe allergic reaction/atopy
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • xerophthalmia/dry eyes
  • cataract/lens opacification
  • retinopathy
  • visual loss/blindness/amblyopia
  • dizziness
  • malabsorption/chronic diarrhea/steatorrhea
  • intestinal perforation
  • pancreatitis
  • splenomegaly
  • abnormal pleura/hydrothorax/pleuresia/pleural effusion/chylothorax
  • lung/pulmonary infiltrates
  • hemoptysis
  • mitral valve prolapse/incompetence/insufficiency/regurgitation/ring anomaly
  • aortic valve anomaly/incompetence/insufficiency/regurgitation/bicuspid
  • myocardium anomalies/myocarditis
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • endocardium anomalies/fibroelastosis/endocarditis
  • angor pectoris/myocardial infarction
  • arterial embolism/thrombosis
  • pulmonary thromboembolism
  • gangrena/necrosis
  • lymphadenopathy/polyadenopathies
  • renal glomerular defect/glomerulopathy
  • renal failure
  • cranial nerves palsy
  • retrobulbar optic neuritis
  • neuritis/polyneuritis/multineuritis
  • transient cerebral ischemia/stroke
  • cranial hypertension
  • encephalitis
  • ataxia/incoordination/trouble of the equilibrium
  • pyramidal syndrome
  • hypereflexia
  • seizures/epilepsy/absences/spasms/status epilepticus
  • paresthesia/dysesthesia/hypoesthesia/anesthesia/numbness
  • psychic/psychomotor regression/dementia/intellectual decline
  • troubles of memory/amnesia/hypermnesia
  • psychic/behavioural troubles
  • anorexia
  • myositis
  • osteonecrosis/bone infarction
  • early death/lethality
  • weight loss/loss of appetite/break in weight curve/general health alteration

HPO human phenotypes related to Behcet's Disease:

(show all 70)
id Description Frequency HPO Source Accession
1 orchitis hallmark (90%) HP:0100796
2 abnormality of temperature regulation hallmark (90%) HP:0004370
3 myalgia hallmark (90%) HP:0003326
4 vasculitis hallmark (90%) HP:0002633
5 migraine hallmark (90%) HP:0002076
6 nausea and vomiting hallmark (90%) HP:0002017
7 arthritis hallmark (90%) HP:0001369
8 meningitis hallmark (90%) HP:0001287
9 photophobia hallmark (90%) HP:0000613
10 immunologic hypersensitivity typical (50%) HP:0100326
11 abnormal blistering of the skin typical (50%) HP:0008066
12 thrombophlebitis typical (50%) HP:0004418
13 hemiplegia/hemiparesis typical (50%) HP:0004374
14 reduced consciousness/confusion typical (50%) HP:0004372
15 arthralgia typical (50%) HP:0002829
16 gastrointestinal hemorrhage typical (50%) HP:0002239
17 abdominal pain typical (50%) HP:0002027
18 gait disturbance typical (50%) HP:0001288
19 acne typical (50%) HP:0001061
20 glomerulopathy occasional (7.5%) HP:0100820
21 gangrene occasional (7.5%) HP:0100758
22 retrobulbar optic neuritis occasional (7.5%) HP:0100654
23 myositis occasional (7.5%) HP:0100614
24 aseptic necrosis occasional (7.5%) HP:0010885
25 abnormal pyramidal signs occasional (7.5%) HP:0007256
26 cranial nerve paralysis occasional (7.5%) HP:0006824
27 arterial thrombosis occasional (7.5%) HP:0004420
28 abnormality of the endocardium occasional (7.5%) HP:0004306
29 paresthesia occasional (7.5%) HP:0003401
30 lymphadenopathy occasional (7.5%) HP:0002716
31 cerebral ischemia occasional (7.5%) HP:0002637
32 increased intracranial pressure occasional (7.5%) HP:0002516
33 encephalitis occasional (7.5%) HP:0002383
34 developmental regression occasional (7.5%) HP:0002376
35 memory impairment occasional (7.5%) HP:0002354
36 vertigo occasional (7.5%) HP:0002321
37 incoordination occasional (7.5%) HP:0002311
38 pulmonary embolism occasional (7.5%) HP:0002204
39 pulmonary infiltrates occasional (7.5%) HP:0002113
40 hemoptysis occasional (7.5%) HP:0002105
41 abnormality of the pleura occasional (7.5%) HP:0002103
42 anorexia occasional (7.5%) HP:0002039
43 malabsorption occasional (7.5%) HP:0002024
44 weight loss occasional (7.5%) HP:0001824
45 splenomegaly occasional (7.5%) HP:0001744
46 pancreatitis occasional (7.5%) HP:0001733
47 abnormality of the pericardium occasional (7.5%) HP:0001697
48 coronary artery disease occasional (7.5%) HP:0001677
49 abnormality of the aortic valve occasional (7.5%) HP:0001646
50 abnormality of the myocardium occasional (7.5%) HP:0001637
51 abnormality of the mitral valve occasional (7.5%) HP:0001633
52 hyperreflexia occasional (7.5%) HP:0001347
53 polyneuropathy occasional (7.5%) HP:0001271
54 seizures occasional (7.5%) HP:0001250
55 keratoconjunctivitis sicca occasional (7.5%) HP:0001097
56 cataract occasional (7.5%) HP:0000518
57 visual impairment occasional (7.5%) HP:0000505
58 retinopathy occasional (7.5%) HP:0000488
59 renal insufficiency occasional (7.5%) HP:0000083
60 chorioretinitis HP:0012424
61 erythema HP:0010783
62 genital ulcers HP:0003249
63 superficial thrombophlebitis HP:0002638
64 alopecia areata HP:0002229
65 arthritis HP:0001369
66 iritis HP:0001101
67 iridocyclitis HP:0001094
68 irritability HP:0000737
69 oral ulcer HP:0000155
70 epididymitis HP:0000031

UMLS symptoms related to Behcet's Disease:


vasculitic rash, discharge from eye, snoring, pruritus, oral manifestations, halitosis, exanthema, chest pain

Drugs & Therapeutics for Behcet's Disease

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Drugs for Behcet's Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 88)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MethylprednisoloneapprovedPhase 4, Phase 3, Phase 2108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
2
PrednisoloneapprovedPhase 4, Phase 3, Phase 2108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
3
Fluocinolone Acetonideapproved, investigationalPhase 43967-73-26215
Synonyms:
(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
4b,12-Difluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
6-alpha,9-alpha-Difluoro-16-alpha-hydroxyprednisolone 16,17-acetonide
6.Alpha., 9.alpha.-Difluoro-16.alpha.-h
6.Alpha.,9-Difluoro
6.alpha.,9-Difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
6.alpha.,9.alpha.-Difluoro-16.alpha.-hydroxyprednisolone 16,17-acetonide
6.alpha.-Fluorotriamcinolone acetonide
67-73-2
6a,9a-difluoro-16a-hydroxyprednisolone 16,17-acetonide
6alpha,9-Difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
6alpha,9alpha-Difluoro-11beta,16alpha,17alpha,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
6alpha,9alpha-Difluoro-11beta,16alpha,17alpha,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-Acetonide
6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide
6alpha-Fluorotriamcinolone acetonide
AC-429
AC1L1M1L
AC1Q6ACL
AR-1H0758
Acetonida de fluocinolona
Acetonida de fluocinolona [INN-Spanish]
Acetonide de fluocinolone
Acetonide de fluocinolone [INN-French]
Acetonido de fluocinolona
Acetónida de fluocinolona
Acétonide de fluocinolone
C24H30F2O6
CCRIS 3250
CHEMBL989
CID6215
CPD000058329
Capex
Coriphate
Cortiplastol
D01825
DB00591
Derma-smoothe/fs
Dermalar
Dermatin (steroid)
Dermotic
EINECS 200-668-5
F0657
F8880_FLUKA
F8880_SIGMA
FLUOCINOLONE ACETONIDE
FS
Flucinar
Flucinolone
Flucort
Fluocet
Fluocet (TN)
Fluocinolon acetonid
Fluocinolonacetonid
Fluocinolonacetonidum
Fluocinolone 16,17-acetonide
Fluocinolone Acetonide
Fluocinolone Acetonide 0.01%
Fluocinolone acetonide (JP15/USP/INN)
 
Fluocinolone acetonide [DCIT]
Fluocinolone acetonide [USAN:INN:JAN]
Fluocinoloni acetonidum
Fluocinoloni acetonidum [INN-Latin]
Fluonid
Fluortriamcinolone Acetonide
Fluotrex
Fluovitif
Flupollon
Fluzon
Fs Shampoo
HMS2090I14
HSDB 3083
Iluvien
Jellin
LS-118443
Localyn
Localyn Syntex
MLS000028545
MLS001076276
Medidur
MolPort-002-528-328
NCGC00021301-04
NCI60_042042
NSC 92339
NSC92339
Neo-Synalar
Omniderm
Percutina
Pregna-1,4-diene-3,20-dione, 6.alpha.,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone (8CI)
Prodermin
RS 1401AT
RS-1401 AT
Radiocin
Retisert
Retisert (TN)
S2470_Selleck
SAM002564208
SMR000058329
STOCK1N-55828
Sinalar
Synalar
Synalar (TN)
Synalar Ts
Synalar-HP
Synamol
Synandone
Synandrone
Synemol
Synotic
Synsac
Tefunote
UNII-0CD5FD6S2M
WLN: T F5 E5 B666 GO IO RV AHTTTT&J A BF CQ E FVIQ H H OF -A&BHO -B&ACEF
ZINC03977981
component of Neo-Synalar
flucinolone
ydroxyprednisolone 16,17-acetonide
4Methylprednisolone acetatePhase 4, Phase 3, Phase 21082
5Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 218510
6Methylprednisolone HemisuccinatePhase 4, Phase 3, Phase 21082
7Prednisolone hemisuccinatePhase 4, Phase 3, Phase 21082
8Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 28478
9Prednisolone phosphatePhase 4, Phase 3, Phase 21082
10Prednisolone acetatePhase 4, Phase 3, Phase 21082
11Gastrointestinal AgentsPhase 4, Phase 3, Phase 1, Phase 26401
12HormonesPhase 411748
13Hormone AntagonistsPhase 410002
14Protective AgentsPhase 45651
15glucocorticoidsPhase 43896
16Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 49988
17Antineoplastic Agents, HormonalPhase 44256
18Neuroprotective AgentsPhase 41376
19AntiemeticsPhase 43213
20Omega 3 Fatty AcidNutraceuticalPhase 4912
21
InfliximabapprovedPhase 3, Phase 1, Phase 2349170277-31-3
Synonyms:
Ig gamma-1 chain C region
 
Inflectra
Remicade
Remsima
22
AdalimumabapprovedPhase 3443331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
23
Pregabalinapproved, illicit, investigationalPhase 3340148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
24
Miconazoleapproved, investigationalPhase 3302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
25
Etanerceptapproved, investigationalPhase 3383185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
26Antiviral AgentsPhase 3, Phase 28071
27Dermatologic AgentsPhase 3, Phase 1, Phase 24555
28Interferon-alphaPhase 3, Phase 21028
29interferonsPhase 3, Phase 21930
30AntibodiesPhase 3, Phase 24477
31Antibodies, MonoclonalPhase 3, Phase 22413
32ImmunoglobulinsPhase 3, Phase 24477
33Angiogenesis Modulating AgentsPhase 3, Phase 23611
34Immunosuppressive AgentsPhase 3, Phase 210422
35Angiogenesis InhibitorsPhase 3, Phase 23688
36Analgesics, Non-NarcoticPhase 3, Phase 25184
37AnalgesicsPhase 3, Phase 29358
38Anti-Infective AgentsPhase 3, Phase 217220
39Anti-Bacterial AgentsPhase 3, Phase 29140
40
ApremilastPhase 3, Phase 258608141-41-911561674
Synonyms:
Apremilast
Apremilast (USAN)
CC-10004
 
CHEBI:558773
CHEMBL514800
CID11561674
D08860
N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
41Anti-Inflammatory Agents, Non-SteroidalPhase 3, Phase 23549
42Immunologic FactorsPhase 3, Phase 218483
43Antirheumatic AgentsPhase 3, Phase 2, Phase 18496
44Psychotropic DrugsPhase 35501
45Tranquilizing AgentsPhase 33597
46CoagulantsPhase 31042
47Factor VIIIPhase 3272
48Central Nervous System DepressantsPhase 310016
49CyclosporinsPhase 3873
50Calcineurin InhibitorsPhase 31223

Interventional clinical trials:

(show top 50)    (show all 61)
idNameStatusNCT IDPhase
1Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's DiseaseRecruitingNCT00720928Phase 4
2The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's DiseaseRecruitingNCT01306955Phase 4
3Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein LevelsTerminatedNCT00578578Phase 4
4Clinical Study of TA-650 in Patients With Behcet's Disease (BD) With Special LesionsCompletedNCT01532570Phase 3
5A Study of Adalimumab in Japanese Subjects With Intestinal Behçet's DiseaseCompletedNCT01243671Phase 3
6Phase III Study in Refractory Behcet's DiseaseCompletedNCT00995709Phase 3
7A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behcet's DiseaseRecruitingNCT02307513Phase 3
8A Study to Evaluate Efficacy and Safety of Infliximab in Participant With Moderate-to-Severe Refractory Intestinal Behcet's DiseaseRecruitingNCT02505568Phase 3
9Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB)RecruitingNCT00167583Phase 3
10Efficacy of Humira in Behcet Patients With ArthritisRecruitingNCT01497717Phase 3
11A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-ClonRecruitingNCT01463306Phase 3
12A Study of the Efficacy and Safety of Pregabalin as Add-On Therapy for Partial Onset Seizures in Children Ages 4-16 YearsRecruitingNCT01389596Phase 3
13Study Evaluating Prophylaxis Treatment & Characterizing Efficacy, Safety, & PK Of B-Domain Deleted Recombinant FVIIIRecruitingNCT00543439Phase 3
14A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.RecruitingNCT02072824Phase 3
15Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque PsoriasisActive, not recruitingNCT01690299Phase 3
16Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease UveitisTerminatedNCT02258867Phase 3
17Efficacy of Gevokizumab in the Treatment of Patients With Behçet's Disease Uveitis (EYEGUARD™-B)TerminatedNCT01965145Phase 3
18Long-term Safety of Gevokizumab in the Treatment of Patients With Chronic Non-infectious Uveitis (EYEGUARD-X)TerminatedNCT02375685Phase 3
19An Open-label, Rollover Study Providing Continued Dosing of Gevokizumab in Order to Assess Long-term Gevokizumab Safety DataTerminatedNCT02258854Phase 3
20A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet DiseaseCompletedNCT00866359Phase 2
21Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's DiseaseCompletedNCT00700297Phase 2
22Low Dose Interferon Alpha Treatment for Oral Ulcers of Behcet's DiseaseCompletedNCT00483184Phase 2
23HAT in Eye Complications of Behcet's DiseaseCompletedNCT00001865Phase 2
24Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's DiseaseCompletedNCT00664599Phase 2
25Intravitreal Infliximab in Refractory Uveitis in Behcet's Disease: A Safety and Efficacy Clinical StudyCompletedNCT02620618Phase 1, Phase 2
26Anakinra for Behcet s DiseaseCompletedNCT01441076Phase 1, Phase 2
27Ilaris (Canakinumab) in the Schnitzler SyndromeCompletedNCT01245127Phase 2
28Efficacy and Safety Study of Two Doses of Apremilast (CC-10004) In Japanese Subjects With Moderate-To-Severe Plaque-Type PsoriasisCompletedNCT01988103Phase 2
29Safety and Efficacy of AIN457 in Noninfectious UveitisCompletedNCT00685399Phase 2
30Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory DiseasesRecruitingNCT01988506Phase 2
31Efficacy and Safety of Ustekinumab, a Human Monoclonal Anti-IL-12/IL-23 Antibody, in Patients With Behçet DiseaseNot yet recruitingNCT02648581Phase 2
321 Year Canakinumab Treatment in Behcet's Disease Patients With Neurologic or Vascular InvolvementNot yet recruitingNCT02756650Phase 2
33A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's DiseaseWithdrawnNCT01211977Phase 1, Phase 2
34Hematopoietic Stem Cell Support in VasculitisRecruitingNCT00278512Phase 1
35Stem Cell Transplantation for the Treatment of Knee OsteoarthritisEnrolling by invitationNCT00550524Phase 1
36Stem Cell Transplantation in Ocular Lesions of Behcet's DiseaseTerminatedNCT00550498Phase 1
37Psychological Symptoms in Patients With Behcet's Disease by SCL90-RCompletedNCT00699985
38Behçet's Disease and Eosinophil Cationic ProteinCompletedNCT01584778
39MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASECompletedNCT01780363
40The Relationship Between Serum Levels of Angiogenin, bFGF, VEGF and Ocular Involvement in Patients With Behçet's DiseaseCompletedNCT01720628
41Educational Needs of Patients With Systemic VasculitisCompletedNCT02190929
42Reproductive Health in Men and Women With VasculitisCompletedNCT02176070
43Vasculitis Illness Perception (VIP) StudyCompletedNCT02190916
44Impact of Vasculitis on Employment and IncomeCompletedNCT02476292
45Uveitis Gene-Expression ProfilingCompletedNCT00874471
46Biological Markers in Retinal VasculitisCompletedNCT00050492
47Evaluation and Treatment of Patients With Inflammatory Eye DiseasesCompletedNCT00006188
48Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's DiseaseRecruitingNCT00931957
49Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)RecruitingNCT01960790
50A Prospective, Mono-Country and Multi-center Study to Observe Safety and Effectiveness of Adalimumab in KoREan Intestinal Behcet's Disease(BD) PatientsRecruitingNCT02687828

Search NIH Clinical Center for Behcet's Disease

Inferred drug relations via UMLS65/NDF-RT43:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Behcet's Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Behcet's Disease:
Bone marrow-derived stem cells for treatment of ocular lesions Behcet's disease
Embryonic/Adult Cultured Cells Related to Behcet's Disease:
Bone marrow-derived stem cells, PMIDs: 21199472, 23773637


Cochrane evidence based reviews: behcet syndrome

Genetic Tests for Behcet's Disease

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Anatomical Context for Behcet's Disease

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MalaCards organs/tissues related to Behcet's Disease:

33
Eye, Skin, Spinal cord, Brain, Bone, T cells, Liver

Animal Models for Behcet's Disease or affiliated genes

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MGI Mouse Phenotypes related to Behcet's Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537010.6CCR1, F5, IL10, IL12RB2, LTA, MEFV
2MP:000538110.6CCR1, IL10, IL12RB2, IL23R, NOD2, TLR4
3MP:000537610.3CCR1, CRP, F5, IL10, IL12RB2, IL23R
4MP:000539710.2CCR1, ERAP1, IL10, IL12RB2, IL23R, LTA
5MP:000538710.2CCR1, CRP, ERAP1, IL10, IL12RB2, IL23R

Publications for Behcet's Disease

About this section

Articles related to Behcet's Disease:

(show top 50)    (show all 310)
idTitleAuthorsYear
1
Endovascular Treatment for Proximal Anastomotic Pseudoaneurysm after Total Arch Replacement in Behcet's Disease. (27174345)
2016
2
The saga of diagnostic/classification criteria in Behcet's disease. (25879654)
2015
3
Behcet's disease presenting with recurrent ocular, oral, and scrotal inflammatory lesions in a young Tanzanian man: a case report. (25356270)
2014
4
Acute inferior myocardial infarction in a young male patient associated with Behcet's disease and sildenafil. (24448432)
2014
5
The relation of PON1-L55M gene polymorphism and clinical manifestation of Behcet's disease. (24936519)
2014
6
A case of Behcet's disease complicated by carotid-oesophageal fistula. (23776286)
2014
7
Expression of TNF-I+, APRIL and BCMA in Behcet's disease. (25759827)
2014
8
The impact of personality on quality of life and disease activity in patients with Behcet's disease: a pilot study. (24342057)
2013
9
Pro-inflammatory cytokine and caspase-1 responses to pattern recognition receptor activation of neutrophils and dendritic cells in Behcet's disease. (23325038)
2013
10
Anakinra treatment in drug-resistant Behcet's disease: a case series. (24305945)
2013
11
Behcet's disease presenting with sudden-onset paraplegia due to anterior spinal artery involvement: 1-year follow-up of rehabilitation in conjunction with medication. (22193225)
2013
12
Incidence, prevalence and clinical characteristics of Behcet's disease in southern Sweden. (23012468)
2013
13
Autoantibodies against complement C1q in patients with Behcet's disease: association with vascular involvement. (23564409)
2013
14
Impact of the positive pathergy test on the performance of classification/diagnosis criteria for Behcet's disease. (22476858)
2013
15
Successful long-term triple disease control by ustekinumab in a patient with Behcet's disease, psoriasis and hidradenitis suppurativa. (23148307)
2013
16
Does Behcet's disease associate with neuropathic pain syndrome and impaired well-being? (23001467)
2013
17
Relationships of HLA-B51 or B5 genotype with Behcet's disease clinical characteristics: systematic review and meta-analyses of observational studies. (22240504)
2012
18
Visfatin levels in Behcet's disease. (21494798)
2012
19
CC chemokine receptor 5 polymorphism in Italian patients with Behcet's disease. (22966075)
2012
20
Mediterranean fever gene mutations in Greek patients with Behcet's disease. (22808562)
2012
21
Behcet's disease with aneurysm of internal iliac artery and percutaneous treatment. (22159243)
2012
22
Association of amyotrophic lateral sclerosis and Behcet's disease: is there a relationship? A multi-national case series. (22234492)
2012
23
Musculoskeletal Findings in Behcet's Disease. (21961082)
2012
24
Clinical characteristics of neuro-Behcet's disease in Japan: a multicenter retrospective analysis. (21935641)
2012
25
The frequency of MEFV gene mutations in Behcet's disease and their relation with clinical findings. (21901355)
2012
26
CTLA-4 polymorphisms and susceptibility to Behcet's disease: a meta-analysis. (22722994)
2012
27
Bilateral Knee Pain Associated with Bone Infarction in a Patient with Behcet's Disease. (23198245)
2012
28
Recurrent vulval ulceration: could it be Behcet's disease? (23033529)
2012
29
Cognitive impairment in neuro-Behcet's disease and multiple sclerosis: a comparative study. (22720779)
2012
30
Urokinase plasminogen activator receptor levels in Behcet's disease. (21470667)
2011
31
Obstruction of the superior vena cava and stenosis of the right brachiocephalic vein in a patient with Adamantiades-Behcet's disease. (24391429)
2011
32
Investigation of bacterial and viral agents and immune status in Behcet's disease patients from Iran. (21816027)
2011
33
Endocardial fibroelastosis of the right ventricle and tricuspid valve in a young adult with Behcet's disease. (20202032)
2010
34
Narcolepsy and Behcet's disease: report of a Chinese-Taiwanese case. (20022557)
2010
35
Lack of association of two polymorphisms of IRF5 with Behcet's disease. (19816589)
2009
36
Inhibition of Behcet's disease by calcitonin. (19299090)
2009
37
TNF-alpha gene polymorphisms in Iranian Azeri Turkish patients with Behcet's Disease. (19774383)
2009
38
Effects of vitamin D on expression of Toll-like receptors of monocytes from patients with Behcet's disease. (18411217)
2008
39
Proteomic surveillance of autoimmunity in Behcet's disease with uveitis: selenium binding protein is a novel autoantigen in Behcet's disease. (17343851)
2007
40
Oxidative stress in patients with Behcet's disease: I correlation with severity and clinical parameters. (17408439)
2007
41
Cytochrome P450 polymorphisms in patients with Behcet's disease. (17269966)
2007
42
Selective anterograde amnesia with thalamus and hippocampal lesions in neuro-Behcet's disease. (17412491)
2007
43
A case of Behcet's disease with scleromalacia perforans. (15840606)
2005
44
Transverse myelitis after lumbar steroid injection in a patient with Behcet's disease. (16010282)
2005
45
Rapidly-progressive glomerulonephritis in a patient with Behcet's disease: successful treatment with intravenous cyclophosphamide. (15986085)
2005
46
Involvement of Th1 cells and heat shock protein 60 in the pathogenesis of intestinal Behcet's disease. (15654837)
2005
47
HLA class I and class II genotyping in patients with Behcet's disease: a regional study of eastern part of Turkey. (15304011)
2004
48
Conn's syndrome associated with Behcet's disease. (12589107)
2003
49
Association of MICA polymorphism with HLA-B51 and disease severity in Korean patients with Behcet's disease. (12068141)
2002
50
Anuric acute renal failure secondary to megalocytic interstitial nephritis in a patient with Behcet's disease. (11140812)
2000

Variations for Behcet's Disease

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Expression for genes affiliated with Behcet's Disease

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Search GEO for disease gene expression data for Behcet's Disease.

Pathways for genes affiliated with Behcet's Disease

About this section

Pathways related to Behcet's Disease according to GeneCards Suite gene sharing:

(show top 19)    (show all 20)
idSuper pathwaysScoreTop Affiliating Genes
110.4IL10, IL12RB2, STAT4
210.4IL10, IL12RB2, STAT4
3
Show member pathways
10.4IL23R, STAT4, TLR4
410.4IL10, TLR4, TNF
510.4IL10, TLR4, TNF
610.4IL10, TLR4, TNF
710.3LTA, TLR4, TNF
810.3LTA, TLR4, TNF
910.3ERAP1, HLA-B, HLA-C
10
Show member pathways
10.3IL10, IL12RB2, IL23R, STAT4
1110.3IL10, LTA, TLR4, TNF
1210.3IL10, NOD2, TLR4, TNF
1310.3IL10, IL12RB2, IL23R, LTA, TNF
14
Show member pathways
10.3HLA-B, HLA-C, IL10, LTA, TNF
15
Show member pathways
10.3HLA-B, HLA-C, LTA, TLR4, TNF
16
Show member pathways
10.2IL10, IL12RB2, IL23R, LTA, STAT4, TLR4
17
Show member pathways
10.1CCR1, IL10, IL12RB2, IL23R, LTA, STAT4
18
Show member pathways
10.0HLA-B, HLA-C, IL10, IL12RB2, IL23R, KLRC4
19
Show member pathways
10.0CRP, ERAP1, HLA-B, HLA-C, IL12RB2, IL23R

GO Terms for genes affiliated with Behcet's Disease

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Biological processes related to Behcet's Disease according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1receptor biosynthetic processGO:003280011.0IL10, TNF
2positive regulation of interleukin-8 biosynthetic processGO:004541611.0TLR4, TNF
3positive regulation of chemokine productionGO:003272211.0TLR4, TNF
4negative regulation of cytokine secretion involved in immune responseGO:000274011.0IL10, TNF
5positive regulation of T cell mediated cytotoxicityGO:000191611.0HLA-B, IL23R
6positive regulation of chronic inflammatory response to antigenic stimulusGO:000287611.0LTA, TNF
7negative regulation of interleukin-12 productionGO:003269510.9IL10, MEFV
8positive regulation of nitric-oxide synthase biosynthetic processGO:005177010.9NOD2, TLR4
9negative regulation of growth of symbiont in hostGO:004413010.9IL10, TNF
10negative regulation of interleukin-6 productionGO:003271510.8IL10, TLR4, TNF
11defense response to Gram-positive bacteriumGO:005083010.8CRP, LTA, TNF
12positive regulation of MHC class II biosynthetic processGO:004534810.8IL10, TLR4
13positive regulation of osteoclast differentiationGO:004567210.7IL23R, TNF
14activation of MAPK activityGO:000018710.7NOD2, TLR4, TNF
15positive regulation of interferon-gamma productionGO:003272910.7IL12RB2, IL23R, LTA, TLR4, TNF
16defense responseGO:000695210.6HLA-B, NOD2, TNF
17inflammatory responseGO:000695410.5CRP, IL10, IL23R, TNF
18immune responseGO:000695510.4CCR1, IL10, TLR4, TNF
19response to lipopolysaccharideGO:003249610.3IL10, IL12RB2, IL23R, LTA
20defense response to bacteriumGO:004274210.0IL10, MICA, NOD2, TLR4, TNF

Sources for Behcet's Disease

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet