MCID: BHC002
MIFTS: 60

Behcet's Disease malady

Categories: Rare diseases, Neuronal diseases, Eye diseases, Cardiovascular diseases, Nephrological diseases, Bone diseases, Skin diseases

Aliases & Classifications for Behcet's Disease

About this section
Sources:
32LifeMap Discovery®, 10Disease Ontology, 45NIH Rare Diseases, 46NINDS, 12DISEASES, 23Genetics Home Reference, 36MeSH, 65UMLS, 35MedlinePlus, 47Novoseek, 51Orphanet, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Behcet's Disease:

Name: Behcet's Disease 32 10 45 46 12
Behcet Syndrome 10 45 23 36 65
Behcet's Syndrome 10 45 23 35
Behcet Disease 45 23 47
Adamantiades-Behcet Disease 10 23
Triple Symptom Complex 10 23
 
Behçet Disease 23 51
Behcet Triple Symptom Complex 23
Old Silk Route Disease 23
Behet's Syndrome 10
Bd 45

Characteristics:

Orphanet epidemiological data:

51
behçet disease:
Inheritance: Multigenic/multifactorial; Prevalence: 1-5/10000 (Japan),>1/1000 (Turkey); Age of onset: Adolescent,Adult,Childhood; Age of death: adult

Classifications:



External Ids:

Disease Ontology10 DOID:13241
ICD1027 M35.2
ICD9CM29 136.1
MeSH36 D001528
NCIt42 C34416
Orphanet51 117
ICD10 via Orphanet28 M35.2
MESH via Orphanet37 D001528
UMLS via Orphanet66 C0004943
UMLS65 C0004943

Summaries for Behcet's Disease

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NIH Rare Diseases:45 Behcet's disease is a chronic multisystem inflammatory disorder characterized by ulcers affecting the mouth and genitals, various skin lesions, and abnormalities affecting the eyes. in some people, the disease also results in arthritis (swollen, painful, stiff joints), skin problems, and inflammation of the digestive tract, brain, and spinal cord. although it can happen at any age, symptoms generally begin when individuals are in their 20s or 30s. the disease is common in japan, turkey and israel, and less common in the united states. the exact cause of behcet's disease is still unknown.  treatment is symptomatic and supportive. experience is evolving with the use of interferon-alpha and with agents which inhibit tumor necrosis factor (tnf) in the treatment of behçet’s disease. behcet's disease is a lifelong disorder that comes and goes. spontaneous remission over time is common for individuals with behçet’s disease but permanent remission of symptoms has not been reported. last updated: 5/25/2015

MalaCards based summary: Behcet's Disease, also known as behcet syndrome, is related to diamond-blackfan anemia 1 and bd syndrome, and has symptoms including orchitis, abnormality of temperature regulation and myalgia. An important gene associated with Behcet's Disease is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways are Jak/STAT Signaling Pathway and Th2 Differentiation Pathway. The drug thalidomide has been mentioned in the context of this disorder. Affiliated tissues include eye, skin and brain, and related mouse phenotypes are liver/biliary system and digestive/alimentary.

Disease Ontology:10 A vasculitis that is characterized by an autoimmune mediated inflammation of the blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis.

Genetics Home Reference:23 Behçet disease is an inflammatory condition that affects many parts of the body. The health problems associated with Behçet disease result from widespread inflammation of blood vessels (vasculitis). This inflammation most commonly affects the mouth, genitals, skin, and eyes.

MedlinePlus:35 Behcet's syndrome is a disease that involves vasculitis, which is inflammation of the blood vessels. it causes problems in many parts of the body. the most common symptoms are sores in the mouth sores on the sex organs other skin sores swelling of parts of the eye pain, swelling and stiffness of the joints more serious problems can include meningitis, blood clots, inflammation of the digestive system and blindness. doctors aren't sure what causes behcet's. it is rare in the united states, but is common in the middle east and asia. it mainly affects people in their 20s and 30s. diagnosing behcet's can take a long time, because symptoms may come and go, and it may take months or even years to have all of the symptoms. there is no cure. treatment focuses on reducing pain and preventing serious problems. most people can control symptoms with treatment. nih: national institute of arthritis and musculoskeletal and skin diseases

NINDS:46 Behcet's disease is a rare, chronic inflammatory disorder. The cause of Behcet's disease is unknown, but current research suggests that both genetic and

Wikipedia:68 Behçet\'s disease or Behçet disease (/bɛˈtʃɛt/), sometimes called Behçet\'s syndrome, Morbus... more...

Related Diseases for Behcet's Disease

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Diseases related to Behcet's Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 153)
idRelated DiseaseScoreTop Affiliating Genes
1diamond-blackfan anemia 132.9CRP, IL10, TNF
2bd syndrome12.3
3diamond-blackfan anemia11.4
4intellectual disability - athetosis - microphthalmia11.4
5behcet's syndrome arthropathy11.3
6spondyloepiphyseal dysplasia-brachydactyly and distinctive speech11.3
7spondyloepiphyseal dysplasia, cantu type11.3
8anti-hla hyperimmunization10.8HLA-B, TLR4, TNF
9monocular exotropia10.8HLA-B, MICA, TNF
10rhinoscleroma10.8CRP, MEFV, TNF
11blue color blindness10.8CRP, HLA-B, MEFV, TNF
12ureteral disease10.8CRP, MEFV, TNF
13acneiform dermatitis10.8HLA-B, HLA-C, TNF
14alcohol-induced mental disorder10.8CRP, HLA-B, MICA, TNF
15hypercementosis10.8HLA-B, IL10, TNF
16punctate palmoplantar keratoderma type 210.8IL10, TNF
17cytoplasmic body myopathy10.8HLA-B, IL10, TNF
18familial mediterranean fever, ad10.8CRP, MEFV, TNF
19tuberculoid leprosy10.8CRP, MEFV, TNF
20hodgkin's granuloma10.8CRP, HLA-B, MEFV, TNF
21placental abruption10.8HLA-B, IL10, MEFV, TNF
22inflammatory spondylopathy10.8HLA-B, LTA, TNF
23achalasia10.8IL10, LTA, TNF
24porphyria10.8CRP, LTA, TLR4, TNF
25idiopathic spinal cord herniation10.8IL10, TLR4, TNF
26methylmalonic acidemia10.8HLA-B, IL10, TLR4, TNF
27cholera10.8HLA-B, IL10, TNF
28precursor b lymphoblastic lymphoma/leukemia10.8IL10, LTA, TNF
29tracheal stenosis10.8HLA-B, IL10, TNF
30early-onset, autosomal dominant alzheimer disease10.8IL10, SAG, TNF
31kernicterus due to isoimmunization10.7HLA-B, IL10, SAG, TNF
32primary progressive freezing gait10.7IL10, TNF
33peritoneal mesothelioma10.7CRP, MEFV, TNF
34microsomia hemifacial radial defects10.7HLA-B, TNF
35funisitis10.7CRP, IL10, TLR4, TNF
36meningitis10.7CRP, IL10, TLR4, TNF
37trachoma10.7IL10, TLR4, TNF
38commensal bacterial infectious disease10.7CRP, IL10, TLR4, TNF
39limited scleroderma10.7CRP, HLA-B, IL10, TNF
40multiple symmetric lipomatosis10.7IL10, LTA, TLR4, TNF
41constant exophthalmos10.7CRP, IL10, TNF
42dentin dysplasia10.7HLA-B, IL10, TNF
43diffuse scleroderma10.7CRP, IL10, TLR4, TNF
44acute gonococcal epididymo-orchitis10.7IL10, TLR4, TNF
45squamous cell papilloma10.7HLA-B, HLA-C, LTA
46hemolytic anemia10.7HLA-B, HLA-C, IL10, TNF
47fatty liver disease10.7CRP, HLA-B, TNF
48lateral sclerosis10.7CRP, IL10, TNF
49moderately severe hemophilia a10.7F5, IL10, TNF
50chronic cystitis10.7CRP, TLR4, TNF

Graphical network of the top 20 diseases related to Behcet's Disease:



Diseases related to behcet's disease

Symptoms for Behcet's Disease

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Symptoms:

 51 (show all 67)
  • photophobia
  • follicular/erythematous/edematous papules/milium
  • enanthema/aphtosa/aphta/leukoplakia
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • vascularitis/vasculitides/arteritis
  • testes inflammation/orchitis
  • facial pain/cephalalgia/migraine
  • meningitis/meningeal syndrome
  • myalgia/muscular pain
  • arthritis/synovitis/synovial proliferation
  • fever/chilling
  • asthenia/fatigue/weakness
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • acne/acnea
  • acute abdominal pain/colic
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • venous thrombosis/phlebitis/thrombophlebitis
  • abnormal gait
  • hemiplegia/diplegia/hemiparesia/limb palsy
  • obnubilation/coma/lethargia/desorientation
  • articular/joint pain/arthralgia
  • severe allergic reaction/atopy
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • xerophthalmia/dry eyes
  • cataract/lens opacification
  • retinopathy
  • visual loss/blindness/amblyopia
  • dizziness
  • malabsorption/chronic diarrhea/steatorrhea
  • intestinal perforation
  • pancreatitis
  • splenomegaly
  • abnormal pleura/hydrothorax/pleuresia/pleural effusion/chylothorax
  • lung/pulmonary infiltrates
  • hemoptysis
  • mitral valve prolapse/incompetence/insufficiency/regurgitation/ring anomaly
  • aortic valve anomaly/incompetence/insufficiency/regurgitation/bicuspid
  • myocardium anomalies/myocarditis
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • endocardium anomalies/fibroelastosis/endocarditis
  • angor pectoris/myocardial infarction
  • arterial embolism/thrombosis
  • pulmonary thromboembolism
  • gangrena/necrosis
  • lymphadenopathy/polyadenopathies
  • renal glomerular defect/glomerulopathy
  • renal failure
  • cranial nerves palsy
  • retrobulbar optic neuritis
  • neuritis/polyneuritis/multineuritis
  • transient cerebral ischemia/stroke
  • cranial hypertension
  • encephalitis
  • ataxia/incoordination/trouble of the equilibrium
  • pyramidal syndrome
  • hypereflexia
  • seizures/epilepsy/absences/spasms/status epilepticus
  • paresthesia/dysesthesia/hypoesthesia/anesthesia/numbness
  • psychic/psychomotor regression/dementia/intellectual decline
  • troubles of memory/amnesia/hypermnesia
  • psychic/behavioural troubles
  • anorexia
  • myositis
  • osteonecrosis/bone infarction
  • early death/lethality
  • weight loss/loss of appetite/break in weight curve/general health alteration

HPO human phenotypes related to Behcet's Disease:

(show all 70)
id Description Frequency HPO Source Accession
1 orchitis hallmark (90%) HP:0100796
2 abnormality of temperature regulation hallmark (90%) HP:0004370
3 myalgia hallmark (90%) HP:0003326
4 vasculitis hallmark (90%) HP:0002633
5 migraine hallmark (90%) HP:0002076
6 nausea and vomiting hallmark (90%) HP:0002017
7 arthritis hallmark (90%) HP:0001369
8 meningitis hallmark (90%) HP:0001287
9 photophobia hallmark (90%) HP:0000613
10 immunologic hypersensitivity typical (50%) HP:0100326
11 abnormal blistering of the skin typical (50%) HP:0008066
12 thrombophlebitis typical (50%) HP:0004418
13 hemiplegia/hemiparesis typical (50%) HP:0004374
14 reduced consciousness/confusion typical (50%) HP:0004372
15 arthralgia typical (50%) HP:0002829
16 gastrointestinal hemorrhage typical (50%) HP:0002239
17 abdominal pain typical (50%) HP:0002027
18 gait disturbance typical (50%) HP:0001288
19 acne typical (50%) HP:0001061
20 glomerulopathy occasional (7.5%) HP:0100820
21 gangrene occasional (7.5%) HP:0100758
22 retrobulbar optic neuritis occasional (7.5%) HP:0100654
23 myositis occasional (7.5%) HP:0100614
24 aseptic necrosis occasional (7.5%) HP:0010885
25 abnormal pyramidal signs occasional (7.5%) HP:0007256
26 cranial nerve paralysis occasional (7.5%) HP:0006824
27 arterial thrombosis occasional (7.5%) HP:0004420
28 abnormality of the endocardium occasional (7.5%) HP:0004306
29 paresthesia occasional (7.5%) HP:0003401
30 lymphadenopathy occasional (7.5%) HP:0002716
31 cerebral ischemia occasional (7.5%) HP:0002637
32 increased intracranial pressure occasional (7.5%) HP:0002516
33 encephalitis occasional (7.5%) HP:0002383
34 developmental regression occasional (7.5%) HP:0002376
35 memory impairment occasional (7.5%) HP:0002354
36 vertigo occasional (7.5%) HP:0002321
37 incoordination occasional (7.5%) HP:0002311
38 pulmonary embolism occasional (7.5%) HP:0002204
39 pulmonary infiltrates occasional (7.5%) HP:0002113
40 hemoptysis occasional (7.5%) HP:0002105
41 abnormality of the pleura occasional (7.5%) HP:0002103
42 anorexia occasional (7.5%) HP:0002039
43 malabsorption occasional (7.5%) HP:0002024
44 weight loss occasional (7.5%) HP:0001824
45 splenomegaly occasional (7.5%) HP:0001744
46 pancreatitis occasional (7.5%) HP:0001733
47 abnormality of the pericardium occasional (7.5%) HP:0001697
48 coronary artery disease occasional (7.5%) HP:0001677
49 abnormality of the aortic valve occasional (7.5%) HP:0001646
50 abnormality of the myocardium occasional (7.5%) HP:0001637
51 abnormality of the mitral valve occasional (7.5%) HP:0001633
52 hyperreflexia occasional (7.5%) HP:0001347
53 polyneuropathy occasional (7.5%) HP:0001271
54 seizures occasional (7.5%) HP:0001250
55 keratoconjunctivitis sicca occasional (7.5%) HP:0001097
56 cataract occasional (7.5%) HP:0000518
57 visual impairment occasional (7.5%) HP:0000505
58 retinopathy occasional (7.5%) HP:0000488
59 renal insufficiency occasional (7.5%) HP:0000083
60 chorioretinitis HP:0012424
61 erythema HP:0010783
62 genital ulcers HP:0003249
63 superficial thrombophlebitis HP:0002638
64 alopecia areata HP:0002229
65 arthritis HP:0001369
66 iritis HP:0001101
67 iridocyclitis HP:0001094
68 irritability HP:0000737
69 oral ulcer HP:0000155
70 epididymitis HP:0000031

Drugs & Therapeutics for Behcet's Disease

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Drugs for Behcet's Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 88)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MethylprednisoloneapprovedPhase 4, Phase 3, Phase 2108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
2
PrednisoloneapprovedPhase 4, Phase 3, Phase 2108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
3
Fluocinolone Acetonideapproved, investigationalPhase 43967-73-26215
Synonyms:
(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
4b,12-Difluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
6-alpha,9-alpha-Difluoro-16-alpha-hydroxyprednisolone 16,17-acetonide
6.Alpha., 9.alpha.-Difluoro-16.alpha.-h
6.Alpha.,9-Difluoro
6.alpha.,9-Difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
6.alpha.,9.alpha.-Difluoro-16.alpha.-hydroxyprednisolone 16,17-acetonide
6.alpha.-Fluorotriamcinolone acetonide
67-73-2
6a,9a-difluoro-16a-hydroxyprednisolone 16,17-acetonide
6alpha,9-Difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
6alpha,9alpha-Difluoro-11beta,16alpha,17alpha,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
6alpha,9alpha-Difluoro-11beta,16alpha,17alpha,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-Acetonide
6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide
6alpha-Fluorotriamcinolone acetonide
AC-429
AC1L1M1L
AC1Q6ACL
AR-1H0758
Acetonida de fluocinolona
Acetonida de fluocinolona [INN-Spanish]
Acetonide de fluocinolone
Acetonide de fluocinolone [INN-French]
Acetonido de fluocinolona
Acetónida de fluocinolona
Acétonide de fluocinolone
C24H30F2O6
CCRIS 3250
CHEMBL989
CID6215
CPD000058329
Capex
Coriphate
Cortiplastol
D01825
DB00591
Derma-smoothe/fs
Dermalar
Dermatin (steroid)
Dermotic
EINECS 200-668-5
F0657
F8880_FLUKA
F8880_SIGMA
FLUOCINOLONE ACETONIDE
FS
Flucinar
Flucinolone
Flucort
Fluocet
Fluocet (TN)
Fluocinolon acetonid
Fluocinolonacetonid
Fluocinolonacetonidum
Fluocinolone 16,17-acetonide
Fluocinolone Acetonide
Fluocinolone Acetonide 0.01%
Fluocinolone acetonide (JP15/USP/INN)
 
Fluocinolone acetonide [DCIT]
Fluocinolone acetonide [USAN:INN:JAN]
Fluocinoloni acetonidum
Fluocinoloni acetonidum [INN-Latin]
Fluonid
Fluortriamcinolone Acetonide
Fluotrex
Fluovitif
Flupollon
Fluzon
Fs Shampoo
HMS2090I14
HSDB 3083
Iluvien
Jellin
LS-118443
Localyn
Localyn Syntex
MLS000028545
MLS001076276
Medidur
MolPort-002-528-328
NCGC00021301-04
NCI60_042042
NSC 92339
NSC92339
Neo-Synalar
Omniderm
Percutina
Pregna-1,4-diene-3,20-dione, 6.alpha.,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone (8CI)
Prodermin
RS 1401AT
RS-1401 AT
Radiocin
Retisert
Retisert (TN)
S2470_Selleck
SAM002564208
SMR000058329
STOCK1N-55828
Sinalar
Synalar
Synalar (TN)
Synalar Ts
Synalar-HP
Synamol
Synandone
Synandrone
Synemol
Synotic
Synsac
Tefunote
UNII-0CD5FD6S2M
WLN: T F5 E5 B666 GO IO RV AHTTTT&J A BF CQ E FVIQ H H OF -A&BHO -B&ACEF
ZINC03977981
component of Neo-Synalar
flucinolone
ydroxyprednisolone 16,17-acetonide
4Methylprednisolone acetatePhase 4, Phase 3, Phase 21082
5Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 218510
6Methylprednisolone HemisuccinatePhase 4, Phase 3, Phase 21082
7Prednisolone hemisuccinatePhase 4, Phase 3, Phase 21082
8Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 28478
9Prednisolone phosphatePhase 4, Phase 3, Phase 21082
10Prednisolone acetatePhase 4, Phase 3, Phase 21082
11Gastrointestinal AgentsPhase 4, Phase 3, Phase 1, Phase 26401
12HormonesPhase 411748
13Hormone AntagonistsPhase 410002
14Protective AgentsPhase 45651
15glucocorticoidsPhase 43896
16Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 49988
17Antineoplastic Agents, HormonalPhase 44256
18Neuroprotective AgentsPhase 41376
19AntiemeticsPhase 43213
20Omega 3 Fatty AcidNutraceuticalPhase 4912
21
InfliximabapprovedPhase 3, Phase 1, Phase 2349170277-31-3
Synonyms:
Ig gamma-1 chain C region
 
Inflectra
Remicade
Remsima
22
AdalimumabapprovedPhase 3443331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
23
Pregabalinapproved, illicit, investigationalPhase 3340148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
24
Miconazoleapproved, investigationalPhase 3302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
25
Etanerceptapproved, investigationalPhase 3383185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
26Antiviral AgentsPhase 3, Phase 28071
27Dermatologic AgentsPhase 3, Phase 1, Phase 24555
28Interferon-alphaPhase 3, Phase 21028
29interferonsPhase 3, Phase 21930
30AntibodiesPhase 3, Phase 24477
31Antibodies, MonoclonalPhase 3, Phase 22413
32ImmunoglobulinsPhase 3, Phase 24477
33Angiogenesis Modulating AgentsPhase 3, Phase 23611
34Immunosuppressive AgentsPhase 3, Phase 210422
35Angiogenesis InhibitorsPhase 3, Phase 23688
36Analgesics, Non-NarcoticPhase 3, Phase 25184
37AnalgesicsPhase 3, Phase 29358
38Anti-Infective AgentsPhase 3, Phase 217220
39Anti-Bacterial AgentsPhase 3, Phase 29140
40
ApremilastPhase 3, Phase 258608141-41-911561674
Synonyms:
Apremilast
Apremilast (USAN)
CC-10004
 
CHEBI:558773
CHEMBL514800
CID11561674
D08860
N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
41Anti-Inflammatory Agents, Non-SteroidalPhase 3, Phase 23549
42Immunologic FactorsPhase 3, Phase 218483
43Antirheumatic AgentsPhase 3, Phase 2, Phase 18496
44Psychotropic DrugsPhase 35501
45Tranquilizing AgentsPhase 33597
46CoagulantsPhase 31042
47Factor VIIIPhase 3272
48Central Nervous System DepressantsPhase 310016
49CyclosporinsPhase 3873
50Calcineurin InhibitorsPhase 31223

Interventional clinical trials:

(show top 50)    (show all 61)
idNameStatusNCT IDPhase
1Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's DiseaseRecruitingNCT00720928Phase 4
2The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's DiseaseRecruitingNCT01306955Phase 4
3Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein LevelsTerminatedNCT00578578Phase 4
4Clinical Study of TA-650 in Patients With Behcet's Disease (BD) With Special LesionsCompletedNCT01532570Phase 3
5A Study of Adalimumab in Japanese Subjects With Intestinal Behçet's DiseaseCompletedNCT01243671Phase 3
6Phase III Study in Refractory Behcet's DiseaseCompletedNCT00995709Phase 3
7A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behcet's DiseaseRecruitingNCT02307513Phase 3
8A Study to Evaluate Efficacy and Safety of Infliximab in Participant With Moderate-to-Severe Refractory Intestinal Behcet's DiseaseRecruitingNCT02505568Phase 3
9Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet`s Disease (INCYTOB)RecruitingNCT00167583Phase 3
10Efficacy of Humira in Behcet Patients With ArthritisRecruitingNCT01497717Phase 3
11A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-ClonRecruitingNCT01463306Phase 3
12A Study of the Efficacy and Safety of Pregabalin as Add-On Therapy for Partial Onset Seizures in Children Ages 4-16 YearsRecruitingNCT01389596Phase 3
13Study Evaluating Prophylaxis Treatment & Characterizing Efficacy, Safety, & PK Of B-Domain Deleted Recombinant FVIIIRecruitingNCT00543439Phase 3
14A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.RecruitingNCT02072824Phase 3
15Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque PsoriasisActive, not recruitingNCT01690299Phase 3
16Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease UveitisTerminatedNCT02258867Phase 3
17Efficacy of Gevokizumab in the Treatment of Patients With Behçet's Disease Uveitis (EYEGUARD™-B)TerminatedNCT01965145Phase 3
18Long-term Safety of Gevokizumab in the Treatment of Patients With Chronic Non-infectious Uveitis (EYEGUARD-X)TerminatedNCT02375685Phase 3
19An Open-label, Rollover Study Providing Continued Dosing of Gevokizumab in Order to Assess Long-term Gevokizumab Safety DataTerminatedNCT02258854Phase 3
20A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet DiseaseCompletedNCT00866359Phase 2
21Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's DiseaseCompletedNCT00700297Phase 2
22Low Dose Interferon Alpha Treatment for Oral Ulcers of Behcet's DiseaseCompletedNCT00483184Phase 2
23HAT in Eye Complications of Behcet's DiseaseCompletedNCT00001865Phase 2
24Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's DiseaseCompletedNCT00664599Phase 2
25Intravitreal Infliximab in Refractory Uveitis in Behcet's Disease: A Safety and Efficacy Clinical StudyCompletedNCT02620618Phase 1, Phase 2
26Anakinra for Behcet s DiseaseCompletedNCT01441076Phase 1, Phase 2
27Ilaris (Canakinumab) in the Schnitzler SyndromeCompletedNCT01245127Phase 2
28Efficacy and Safety Study of Two Doses of Apremilast (CC-10004) In Japanese Subjects With Moderate-To-Severe Plaque-Type PsoriasisCompletedNCT01988103Phase 2
29Safety and Efficacy of AIN457 in Noninfectious UveitisCompletedNCT00685399Phase 2
30Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory DiseasesRecruitingNCT01988506Phase 2
31Efficacy and Safety of Ustekinumab, a Human Monoclonal Anti-IL-12/IL-23 Antibody, in Patients With Behçet DiseaseNot yet recruitingNCT02648581Phase 2
321 Year Canakinumab Treatment in Behcet's Disease Patients With Neurologic or Vascular InvolvementNot yet recruitingNCT02756650Phase 2
33A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's DiseaseWithdrawnNCT01211977Phase 1, Phase 2
34Hematopoietic Stem Cell Support in VasculitisRecruitingNCT00278512Phase 1
35Stem Cell Transplantation for the Treatment of Knee OsteoarthritisEnrolling by invitationNCT00550524Phase 1
36Stem Cell Transplantation in Ocular Lesions of Behcet's DiseaseTerminatedNCT00550498Phase 1
37Psychological Symptoms in Patients With Behcet's Disease by SCL90-RCompletedNCT00699985
38Behçet's Disease and Eosinophil Cationic ProteinCompletedNCT01584778
39MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASECompletedNCT01780363
40The Relationship Between Serum Levels of Angiogenin, bFGF, VEGF and Ocular Involvement in Patients With Behçet's DiseaseCompletedNCT01720628
41Educational Needs of Patients With Systemic VasculitisCompletedNCT02190929
42Reproductive Health in Men and Women With VasculitisCompletedNCT02176070
43Vasculitis Illness Perception (VIP) StudyCompletedNCT02190916
44Impact of Vasculitis on Employment and IncomeCompletedNCT02476292
45Uveitis Gene-Expression ProfilingCompletedNCT00874471
46Biological Markers in Retinal VasculitisCompletedNCT00050492
47Evaluation and Treatment of Patients With Inflammatory Eye DiseasesCompletedNCT00006188
48Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's DiseaseRecruitingNCT00931957
49Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)RecruitingNCT01960790
50A Prospective, Mono-Country and Multi-center Study to Observe Safety and Effectiveness of Adalimumab in KoREan Intestinal Behcet's Disease(BD) PatientsRecruitingNCT02687828

Search NIH Clinical Center for Behcet's Disease

Inferred drug relations via UMLS65/NDF-RT43:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Behcet's Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Behcet's Disease:
Bone marrow-derived stem cells for treatment of ocular lesions Behcet's disease
Embryonic/Adult Cultured Cells Related to Behcet's Disease:
Bone marrow-derived stem cells, PMIDs: 21199472, 23773637


Cochrane evidence based reviews: behcet syndrome

Genetic Tests for Behcet's Disease

About this section

Anatomical Context for Behcet's Disease

About this section

MalaCards organs/tissues related to Behcet's Disease:

33
Eye, Skin, Brain, Spinal cord, Bone, T cells, Testes

Animal Models for Behcet's Disease or affiliated genes

About this section

MGI Mouse Phenotypes related to Behcet's Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537010.6CCR1, F5, IL10, IL12RB2, LTA, MEFV
2MP:000538110.6CCR1, IL10, IL12RB2, IL23R, NOD2, TLR4
3MP:000537610.3CCR1, CRP, F5, IL10, IL12RB2, IL23R
4MP:000539710.2CCR1, ERAP1, IL10, IL12RB2, IL23R, LTA
5MP:000538710.2CCR1, CRP, ERAP1, IL10, IL12RB2, IL23R

Publications for Behcet's Disease

About this section

Articles related to Behcet's Disease:

(show top 50)    (show all 304)
idTitleAuthorsYear
1
Importance of Neurogenic Bladder as a Cause of Drainage Failure. (27006442)
2016
2
Gray and white matter structural changes in corticobasal syndrome. (26545629)
2016
3
Malignant Mediterranean spotted fever. (26904440)
2015
4
Identification of known and novel germ cell cancer-specific (embryonic) miRs in serum by high-throughput profiling. (25382245)
2014
5
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder. (24393808)
2014
6
Helicobacter pylori-induced loss of survivin and gastric cell viability is attributable to secreted bacterial gamma-glutamyl transpeptidase activity. (23847060)
2013
7
The personal experience of partners of individuals with motor neuron disease. (22973854)
2013
8
Enlarged cavum septum pellucidum as a neurodevelopmental marker in adolescent-onset opiate dependence. (24205275)
2013
9
Girdin and its phosphorylation dynamically regulate neonatal vascular development and pathological neovascularization in the retina. (23195430)
2013
10
Talocalcaneal coalition in Muenke syndrome: report of a patient, review of the literature in FGFR-related craniosynostoses, and consideration of mechanism. (23378035)
2013
11
Paraneoplastic thrombocytosis in ovarian cancer. (22335738)
2012
12
Pilomatrixoma of eyelid in a middle aged. (21587326)
2011
13
Persistent, widespread papilloma formation on the penis of a horse: a novel presentation of equine papillomavirus type 2 infection. (21645140)
2011
14
Pro-inflammatory chemokine C-C motif ligand 16 (CCL-16) dysregulation in irritable bowel syndrome (IBS): a pilot study. (21951809)
2011
15
Therapy modifications and low-density lipoprotein cholesterol goal attainment rates associated with the initiation of generic simvastatin. (19916706)
2010
16
Survival of blunt cardiac rupture after asystolic arrest: a case report. (19359944)
2009
17
Lack of association between metabolic and antioxidant gene polymorphisms (GSTM1, GSTT1, CAT, MnSOD, GPX1) and maternal quitting of smoking in pregnancy--preliminary results]. (20301895)
2009
18
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma. (19380639)
2009
19
Hsp90 regulates the phosphorylation and activity of serum- and glucocorticoid-regulated kinase-1. (18456663)
2008
20
Aggressive Langerhans cell histiocytosis following T-ALL: clonally related neoplasms with persistent expression of constitutively active NOTCH1. (17874453)
2008
21
Intracystic papillary carcinoma: a review of 917 cases. (18661510)
2008
22
Cutaneous and ocular signs of childhood rosacea. (18283173)
2008
23
Decreasing trend of esophageal adenocarcinoma in Hong Kong. (18086768)
2007
24
3D-QSAR CoMFA study on oxindole derivatives as cyclin dependent kinase 1 (CDK1) and cyclin dependent kinase 2 (CDK2) inhibitors. (17266627)
2007
25
Role of nitrergic system in behavioral and neurotoxic effects of amphetamine analogs. (16154200)
2006
26
Apigenin drives the production of reactive oxygen species and initiates a mitochondrial mediated cell death pathway in prostate epithelial cells. (15486995)
2005
27
Neonatal hypophosphatasia and seizures. A case report. (16205618)
2005
28
Analysis of IL4R haplotypes in predisposition to multiple sclerosis. (14712310)
2004
29
Molecular genetic analysis of severe coagulation factor XI deficiency in six Italian patients. (15531455)
2004
30
Novel mutations in the TRIM37 gene in Mulibrey Nanism. (15108285)
2004
31
Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome]. (15196341)
2004
32
Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado-Joseph disease (MJD) gene. (15233999)
2004
33
Risk factors in the development of early technetium-99m dimercaptosuccinic acid renal scintigraphy lesions during first urinary tract infection in children. (12650294)
2003
34
Differential expression of Bcl-2 and Bax may enhance neuroblastoma survival. (12632373)
2003
35
Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes. (12700977)
2003
36
Gingival disease associated with a decorative crown. (11874059)
2002
37
Life-threatening hyperkalemia during combined therapy with angiotensin-converting enzyme inhibitors and spironolactone: an analysis of 25 cases. (11331054)
2001
38
Identification and characterisation of the murine homologue of the gene responsible for cystinosis, Ctns. (11121245)
2000
39
Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule. (10840047)
2000
40
In vitro C3 mRNA expression in Pemphigus vulgaris: complement activation is increased by IL-1alpha and TNF-alpha. (10082594)
1999
41
Solution structure of the recombinant oxidized rabbit uteroglobin using homonuclear and heteronuclear multidimensional NMR. (9874219)
1998
42
Clinical evaluation of bifonazole for moccasin-type tinea pedis. (9476493)
1997
43
Cloning, expression, and regulation of rabbit cyclooxygenase-2 in renal medullary interstitial cells. (9249588)
1997
44
Catalytic cleavage of an RNA target by 2-5A antisense and RNase L. (7797490)
1995
45
Role for diacylglycerol in mediating the actions of ACh on M-current in gastric smooth muscle cells. (1476168)
1992
46
Prenatal diagnosis of Niemann-Pick disease type C. (1499136)
1992
47
Role of the spacer in conferring kappa opioid receptor selectivity to bivalent ligands related to norbinaltorphimine. (1849995)
1991
48
Neuroglial choristoma of the pharynx. (3248532)
1988
49
Hepatic coma. (4343184)
1970
50
Cerebral atherosclerosis in persons with selected diseases. (5681203)
1968

Variations for Behcet's Disease

About this section

Expression for genes affiliated with Behcet's Disease

About this section
Search GEO for disease gene expression data for Behcet's Disease.

Pathways for genes affiliated with Behcet's Disease

About this section

Pathways related to Behcet's Disease according to GeneCards Suite gene sharing:

(show top 19)    (show all 20)
idSuper pathwaysScoreTop Affiliating Genes
110.4IL10, IL12RB2, STAT4
210.4IL10, IL12RB2, STAT4
3
Show member pathways
10.4IL23R, STAT4, TLR4
410.4IL10, TLR4, TNF
510.4IL10, TLR4, TNF
610.4IL10, TLR4, TNF
710.3LTA, TLR4, TNF
810.3LTA, TLR4, TNF
910.3ERAP1, HLA-B, HLA-C
10
Show member pathways
10.3IL10, IL12RB2, IL23R, STAT4
1110.3IL10, LTA, TLR4, TNF
1210.3IL10, NOD2, TLR4, TNF
1310.3IL10, IL12RB2, IL23R, LTA, TNF
14
Show member pathways
10.3HLA-B, HLA-C, IL10, LTA, TNF
15
Show member pathways
10.3HLA-B, HLA-C, LTA, TLR4, TNF
16
Show member pathways
10.2IL10, IL12RB2, IL23R, LTA, STAT4, TLR4
17
Show member pathways
10.1CCR1, IL10, IL12RB2, IL23R, LTA, STAT4
18
Show member pathways
10.0HLA-B, HLA-C, IL10, IL12RB2, IL23R, KLRC4
19
Show member pathways
10.0CRP, ERAP1, HLA-B, HLA-C, IL12RB2, IL23R

GO Terms for genes affiliated with Behcet's Disease

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Biological processes related to Behcet's Disease according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1receptor biosynthetic processGO:003280011.0IL10, TNF
2positive regulation of interleukin-8 biosynthetic processGO:004541611.0TLR4, TNF
3positive regulation of chemokine productionGO:003272211.0TLR4, TNF
4negative regulation of cytokine secretion involved in immune responseGO:000274011.0IL10, TNF
5positive regulation of T cell mediated cytotoxicityGO:000191611.0HLA-B, IL23R
6positive regulation of chronic inflammatory response to antigenic stimulusGO:000287611.0LTA, TNF
7negative regulation of interleukin-12 productionGO:003269510.9IL10, MEFV
8positive regulation of nitric-oxide synthase biosynthetic processGO:005177010.9NOD2, TLR4
9negative regulation of growth of symbiont in hostGO:004413010.9IL10, TNF
10negative regulation of interleukin-6 productionGO:003271510.8IL10, TLR4, TNF
11defense response to Gram-positive bacteriumGO:005083010.8CRP, LTA, TNF
12positive regulation of MHC class II biosynthetic processGO:004534810.8IL10, TLR4
13positive regulation of osteoclast differentiationGO:004567210.7IL23R, TNF
14activation of MAPK activityGO:000018710.7NOD2, TLR4, TNF
15positive regulation of interferon-gamma productionGO:003272910.7IL12RB2, IL23R, LTA, TLR4, TNF
16defense responseGO:000695210.6HLA-B, NOD2, TNF
17inflammatory responseGO:000695410.5CRP, IL10, IL23R, TNF
18immune responseGO:000695510.4CCR1, IL10, TLR4, TNF
19response to lipopolysaccharideGO:003249610.3IL10, IL12RB2, IL23R, LTA
20defense response to bacteriumGO:004274210.0IL10, MICA, NOD2, TLR4, TNF

Sources for Behcet's Disease

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet