Bell's Palsy malady
Categories: Rare diseases, Neuronal diseases
Aliases & Descriptions for Bell's Palsy:
Orphanet epidemiological data:52
Inheritance: Not applicable; Prevalence: 1-5/10000 (United States),1-5/10000 (Worldwide),1-5/10000 (Italy),1-5/10000 (Spain),1-5/10000 (Canada),1-5/10000 (Denmark),1-5/10000 (Europe); Age of onset: Adolescent,Adult,Elderly; Age of death: normal life expectancy
Global: Rare diseases
Anatomical: Neuronal diseases
ICD10: 29 28
Rare neurological diseases
NIH Rare Diseases:46 Bell's palsy is a form of temporary facial paralysis which results from damage or trauma to one of the facial nerves. this disorder is characterized by the sudden onset of facial paralysis that often affects just one side and can cause significant facial distortion. symptoms vary, but may include twitching, weakness, drooping eyelid or corner of the mouth, drooling, dry eye or mouth, impairment of taste, and excessive tearing in the eye. while the exact cause is unknown, many researchers believe that a virus may lead to swelling of the 7th cranial nerve. steroids, such as prednisone, may reduce the inflammation and swelling. other medications used to treat bell's palsy include acyclovir (to fight viral infections) and aspirin, acetaminophen, or ibuprofen (to relieve pain). physical therapy, facial massage and acupuncture have also been used. last updated: 1/22/2016
MalaCards based summary: Bell's Palsy, also known as bell palsy, is related to essential tremor and recurrent peripheral facial palsy, and has symptoms including hemiplegia, ophthalmoplegia and oral manifestations. An important gene associated with Bell's Palsy is HS1BP3 (HCLS1 Binding Protein 3), and among its related pathways are Calcineurin-regulated NFAT-dependent transcription in lymphocytes and IgA-Producing B Cells in the Intestine. The drugs scopolamine and scopolamine hydrobromide have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and tongue.
Disease Ontology:11 A facial paralysis resulting from dysfunction in the cranial nerve vii (facial nerve).
MedlinePlus:36 Bell's palsy is the most common cause of facial paralysis. it usually affects just one side of the face. symptoms appear suddenly and are at their worst about 48 hours after they start. they can range from mild to severe and include twitching weakness paralysis drooping eyelid or corner of mouth drooling dry eye or mouth excessive tearing in the eye impaired ability to taste scientists think that a viral infection makes the facial nerve swell or become inflamed. you are most likely to get bell's palsy if you are pregnant, diabetic or sick with a cold or flu. three out of four patients improve without treatment. with or without treatment, most people begin to get better within 2 weeks and recover completely within 3 to 6 months. nih: national institute of neurological disorders and stroke
NINDS:47 Bell's palsy is a form of temporary facial paralysis resulting from damage or trauma to the 7th cranial nerve, one of the facial nerves.
Wikipedia:69 Bell\'s palsy is a type of facial paralysis that results in an inability to control the facial muscles... more...
UMLS symptoms related to Bell's Palsy:hemiplegia, ophthalmoplegia, oral manifestations, sciatica, facial paresis, facial palsy, upper motor neuron, facial palsy, lower motor neuron, hemifacial paralysis, back pain, headache, flaccid muscle tone, pain, seizures, syncope, tremor, chronic pain, muscle weakness, vertigo/dizziness, diaphragmatic paresis, unilateral facial paresis, generalized muscle weakness, sleeplessness
Drugs for Bell's Palsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show all 14)
Interventional clinical trials:(show all 37)
Search NIH Clinical Center for Bell's Palsy
Inferred drug relations via UMLS66/NDF-RT44:
MalaCards organs/tissues related to Bell's Palsy:34
Eye, Testes, Tongue, Spinal cord, Neutrophil, Brain, Cortex
Articles related to Bell's Palsy:(show top 50) (show all 586)
Search GEO for disease gene expression data for Bell's Palsy.
Pathways related to Bell's Palsy according to GeneCards Suite gene sharing:
29ICD10 via Orphanet
38MESH via Orphanet
51OMIM via Orphanet
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
67UMLS via Orphanet