MCID: BNG025
MIFTS: 23

Benign Mammary Dysplasia

Categories: Reproductive diseases, Cancer diseases

Aliases & Classifications for Benign Mammary Dysplasia

MalaCards integrated aliases for Benign Mammary Dysplasia:

Name: Benign Mammary Dysplasia 12 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9504
ICD9CM 34 610.8
ICD10 32 N60

Summaries for Benign Mammary Dysplasia

MalaCards based summary : Benign Mammary Dysplasia is related to solitary cyst of breast and breast cyst. An important gene associated with Benign Mammary Dysplasia is BCL2 (BCL2, Apoptosis Regulator), and among its related pathways/superpathways are TNFR1 Pathway and Pathways in cancer. Affiliated tissues include breast.

Related Diseases for Benign Mammary Dysplasia

Diseases related to Benign Mammary Dysplasia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 solitary cyst of breast 10.3
2 breast cyst 10.3
3 breast fibroadenosis 10.3
4 fibrosclerosis of breast 10.3

Symptoms & Phenotypes for Benign Mammary Dysplasia

Drugs & Therapeutics for Benign Mammary Dysplasia

Search Clinical Trials , NIH Clinical Center for Benign Mammary Dysplasia

Genetic Tests for Benign Mammary Dysplasia

Anatomical Context for Benign Mammary Dysplasia

MalaCards organs/tissues related to Benign Mammary Dysplasia:

38
Breast

Publications for Benign Mammary Dysplasia

Articles related to Benign Mammary Dysplasia:

# Title Authors Year
1
Expression of the apoptotic markers in normal breast epithelium, benign mammary dysplasia and in breast cancer. ( 15478112 )
2004
2
Benign mammary dysplasia. ( 514167 )
1979
3
Modern management of benign mammary dysplasia. ( 470733 )
1979
4
Benign mammary dysplasia. ( 514166 )
1979
5
Aspiration biopsy cytology in proliferating benign mammary dysplasia. ( 277037 )
1978
6
Fibrocystic disease of the breast (benign mammary dysplasia). ( 1165420 )
1975
7
Periductal foam cells in benign mammary dysplasia. ( 1195061 )
1975
8
Neural invasion in benign mammary dysplasia. ( 4719773 )
1973
9
Benign mammary dysplasia. ( 5073961 )
1972

Variations for Benign Mammary Dysplasia

Expression for Benign Mammary Dysplasia

Search GEO for disease gene expression data for Benign Mammary Dysplasia.

Pathways for Benign Mammary Dysplasia

Pathways related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.36 BAK1 BCL2
2 12.31 BAK1 BCL2
3
Show member pathways
12.29 BAK1 BCL2
4
Show member pathways
12.23 BAK1 BCL2
5
Show member pathways
12.08 BAK1 BCL2
6 12.02 BAK1 BCL2
7 11.8 BAK1 BCL2
8 11.74 BAK1 BCL2
9 11.7 BAK1 BCL2
10 11.62 BAK1 BCL2
11 11.6 BAK1 BCL2
12
Show member pathways
11.55 BAK1 BCL2
13 11.49 BAK1 BCL2
14 11.37 BAK1 BCL2
15
Show member pathways
11.29 BAK1 BCL2
16 11.18 BAK1 BCL2
17 10.86 BAK1 BCL2
18
Show member pathways
10.81 BAK1 BCL2
19 10.32 BAK1 BCL2

GO Terms for Benign Mammary Dysplasia

Cellular components related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial outer membrane GO:0005741 9.16 BAK1 BCL2
2 mitochondrial membrane GO:0031966 8.96 BAK1 BCL2
3 pore complex GO:0046930 8.62 BAK1 BCL2

Biological processes related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.57 BAK1 BCL2
2 cell proliferation GO:0008283 9.56 BAK1 BCL2
3 response to drug GO:0042493 9.55 BAK1 BCL2
4 regulation of apoptotic process GO:0042981 9.54 BAK1 BCL2
5 regulation of cell cycle GO:0051726 9.52 BAK1 BCL2
6 response to hydrogen peroxide GO:0042542 9.51 BAK1 BCL2
7 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.49 BAK1 BCL2
8 response to gamma radiation GO:0010332 9.48 BAK1 BCL2
9 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.46 BAK1 BCL2
10 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 9.43 BAK1 BCL2
11 regulation of mitochondrial membrane potential GO:0051881 9.4 BAK1 BCL2
12 release of cytochrome c from mitochondria GO:0001836 9.37 BAK1 BCL2
13 B cell homeostasis GO:0001782 9.32 BAK1 BCL2
14 endoplasmic reticulum calcium ion homeostasis GO:0032469 9.26 BAK1 BCL2
15 regulation of mitochondrial membrane permeability GO:0046902 9.16 BAK1 BCL2
16 regulation of protein heterodimerization activity GO:0043497 8.96 BAK1 BCL2
17 regulation of protein homodimerization activity GO:0043496 8.62 BAK1 BCL2

Molecular functions related to Benign Mammary Dysplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein heterodimerization activity GO:0046982 8.62 BAK1 BCL2

Sources for Benign Mammary Dysplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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