MCID: BNG041
MIFTS: 31

Benign Metastasizing Leiomyoma malady

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Benign Metastasizing Leiomyoma

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Aliases & Descriptions for Benign Metastasizing Leiomyoma:

Name: Benign Metastasizing Leiomyoma 47
 
Benign Metastasizing Leiomyoma of Uterus 67

Classifications:



Summaries for Benign Metastasizing Leiomyoma

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MalaCards based summary: Benign Metastasizing Leiomyoma, also known as benign metastasizing leiomyoma of uterus, is related to leiomyoma and xq12-q13.3 duplication syndrome. An important gene associated with Benign Metastasizing Leiomyoma is DES (Desmin), and among its related pathways are Ovarian Infertility Genes and Aurora B signaling. Affiliated tissues include uterus, lung and lymph node, and related mouse phenotypes are cardiovascular system and cellular.

Related Diseases for Benign Metastasizing Leiomyoma

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Diseases related to Benign Metastasizing Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 132)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyoma10.7
2xq12-q13.3 duplication syndrome10.5ACTC1, DES
3dysembryoplastic neuroepithelial tumor10.5DES, PGR
4her2-receptor positive breast cancer10.5CYP19A1, PGR
5intravascular fasciitis10.5ACTC1, DES
6malignant secondary hypertension10.5CYP19A1, PGR
7retroperitoneum carcinoma10.5CYP19A1, PGR
8simple partial epilepsy10.5ACTC1, PGR
9harding ataxia10.5DES, VIM
10pura syndrome10.5ACTC1, DES
11pleuropulmonary blastoma type 210.5ACTC1, DES
12absence of fingerprints congenital milia10.5DES, VIM
13allergic cutaneous vasculitis10.5CYP19A1, PGR
14pancreatic delta cell neoplasm10.5DES, VIM
15monophasic synovial sarcoma10.5DES, VIM
16bartholin's gland benign neoplasm10.4DES, VIM
17parovarian cyst10.4ACTC1, DES
18malignant adenofibroma10.4DES, VIM
19sclerosing liposarcoma10.4DES, VIM
20congenital structural myopathy10.4PGR, VIM
21extracranial neuroblastoma10.4PGR, VIM
22breast adenoma10.4CYP19A1, PGR
23postcricoid region cancer10.4ACTC1, PGR
24angora hair nevus10.4DES, VIM
25gangliocytoma10.4DES, VIM
26benign mesenchymoma10.4PGR, VIM
27female reproductive endometrioid cancer10.4PGR, VIM
28lymphangiomatosis10.4ACTC1, VIM
29myxoid liposarcoma of the ovary10.4ACTC1, VIM
30iridogoniodysgenesis and skeletal anomalies10.4ACTC1, VIM
31small intestinal sarcoma10.4ACTC1, PGR
32prolapse of lacrimal gland10.4CYP19A1, PGR
33emerinopathy10.4DES, VIM
34skin sarcoma10.4ACTC1, VIM
35orbit rhabdomyosarcoma10.4ACTC1, DES
36serous cystadenocarcinoma10.4PGR, VIM
37uterine body mixed cancer10.4BCL2, PGR
38vulvar alveolar soft part sarcoma10.4ACTC1, VIM
39eccrine papillary adenoma10.4ACTC1, VIM
40malignant peritoneal solitary fibrous tumor10.4ACTC1, VIM
41pineal parenchymal tumor of intermediate differenciation10.3ACTC1, VIM
42myoclonic cerebellar dyssynergia10.3CYP19A1, PGR
43ovarian cystadenocarcinoma10.3ACTC1, VIM
44vascular hemostatic disease10.3ACTC1, VIM
45rheumatic pulmonary valve disease10.3BCL2, PGR
46longitudinal vaginal septum10.3ACTC1, DES
47bladder colonic type adenocarcinoma10.3KRT7, PGR
48pancreatic serous cystic neoplasm10.3KRT7, PGR
49dens in dente and palatal invaginations10.3ACTC1, VIM
50infiltrative basal cell carcinoma10.3KRT7, PGR

Graphical network of the top 20 diseases related to Benign Metastasizing Leiomyoma:



Diseases related to benign metastasizing leiomyoma

Symptoms for Benign Metastasizing Leiomyoma

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Drugs & Therapeutics for Benign Metastasizing Leiomyoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Establishment of Fibroid Tissue BankTerminatedNCT00710346

Search NIH Clinical Center for Benign Metastasizing Leiomyoma

Genetic Tests for Benign Metastasizing Leiomyoma

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Anatomical Context for Benign Metastasizing Leiomyoma

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MalaCards organs/tissues related to Benign Metastasizing Leiomyoma:

35
Uterus, Lung, Lymph node, Appendix, Ovary, Breast, Spinal cord

Animal Models for Benign Metastasizing Leiomyoma or affiliated genes

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MGI Mouse Phenotypes related to Benign Metastasizing Leiomyoma:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.9ACTC1, BCL2, CYP19A1, DES, PGR, VIM
2MP:00053848.2ACTC1, BCL2, CYP19A1, DES, KRT7, PGR
3MP:00053767.3ACTC1, BCL2, CYP19A1, DES, KRT7, LGALS1
4MP:00053697.2ACTC1, BCL2, CYP19A1, DES, LGALS1, PGR

Publications for Benign Metastasizing Leiomyoma

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Articles related to Benign Metastasizing Leiomyoma:

(show top 50)    (show all 104)
idTitleAuthorsYear
1
A rare cause of miliary pattern and respiratory failure - Benign metastasizing leiomyoma. (27178355)
2016
2
Benign metastasizing leiomyoma in triple location: lungs, parametria and appendix. (27582687)
2016
3
Benign Metastasizing Leiomyoma. (27514603)
2016
4
Benign Metastasizing Leiomyoma. (27659239)
2016
5
Cystic Benign Metastasizing Leiomyoma of the Lung Mimicking Hydatid Cyst. (27631636)
2016
6
Pulmonary benign metastasizing leiomyoma: a case report and literature review. (24977035)
2014
7
Difficulty in complete transarterial embolization for pulmonary benign metastasizing leiomyoma with massive hemoptysis. (24272622)
2014
8
Iatrogenic exacerbation of pulmonary arteriovenous malformation in a patient with benign metastasizing leiomyoma. (25473552)
2014
9
Pulmonary Benign Metastasizing Leiomyoma: An Extremely Rare Case. (24715553)
2014
10
Case of concurrent benign metastasizing leiomyoma in the lung and retroperitoneum, with a focus on its etiology. (25131768)
2014
11
Benign metastasizing leiomyoma of the lung: report of a case. (23117336)
2013
12
A rare pancreatic tumor in a 52-year-old Chinese woman. Pancreatic benign metastasizing leiomyoma. (23333466)
2013
13
Elevated 99mTc 3PRGD2 activity in benign metastasizing leiomyoma. (23334126)
2013
14
Benign metastasizing leiomyoma : Case report and review of the literature. (23903362)
2013
15
An undescribed coexistence of benign metastasizing leiomyoma in the lung with serous borderline tumor of the ovary. (23781598)
2013
16
Successful treatment of benign metastasizing leiomyoma with oral alternated chemotherapeutic agents. (24065503)
2013
17
Benign metastasizing leiomyoma: a rare cause of multiple pulmonary nodules. (22632533)
2012
18
Pulmonary benign metastasizing leiomyoma: a case report and review of the literature. (23234399)
2012
19
Benign metastasizing leiomyoma. (21566534)
2012
20
Genomic imbalances in benign metastasizing leiomyoma: characterization by conventional karyotypic, fluorescence in situ hybridization, and whole genome SNP array analysis. (22682624)
2012
21
Benign metastasizing leiomyoma with multiple lymph node metastasis: a case report. (21811430)
2011
22
Pulmonary and retroperitoneal benign metastasizing leiomyoma. (22384439)
2011
23
Clinical benefit of endocrine therapy for benign metastasizing leiomyoma. (21161313)
2011
24
Benign metastasizing leiomyoma of the lung with malignant transformation mimicking mediastinal tumor. (21872133)
2011
25
Benign metastasizing leiomyoma presenting as cystic lung disease: a diagnostic pitfall. (22014060)
2011
26
Benign metastasizing leiomyoma identified using 18F-FDG PET/CT. (20435308)
2010
27
Benign metastasizing leiomyoma. (21045423)
2010
28
Benign metastasizing leiomyoma of the lung: PET findings. (19242303)
2009
29
A case of benign metastasizing leiomyoma treated by surgical castration followed by an aromatase inhibitor, anastrozole. (18523791)
2009
30
Benign metastasizing leiomyoma of the lung: potential role of low-grade malignancy. (19330762)
2009
31
Benign metastasizing leiomyoma of the lung: clinicopathologic, immunohistochemical, and micro-RNA analyses. (18382364)
2008
32
Pulmonary benign metastasizing leiomyoma following hysterectomy: a clinicopathologic correlation. (18520812)
2008
33
Intravascular leiomyomatosis and benign metastasizing leiomyoma: an unusual case. (16803546)
2006
34
A case of benign metastasizing leiomyoma with multiple metastasis to the soft tissue, skeletal muscle, lung and breast. (17017672)
2006
35
Benign metastasizing leiomyoma responsive to megestrol: case report and review of the literature. (16343217)
2005
36
CD10- and CD34-positive periglandular stromal cells in pulmonary benign metastasizing leiomyoma with metaplastic adenomyomatous glands: an ultrastructural and immunohistochemical study. (15688167)
2005
37
Pulmonary benign metastasizing leiomyoma from the uterus in a postmenopausal woman: report of a case. (14714229)
2004
38
Benign metastasizing leiomyoma in the lung: a case report. (12440822)
2002
39
Benign metastasizing leiomyoma. (11972229)
2002
40
Benign metastasizing leiomyoma: clinical, imaging, and pathologic correlation. (11373202)
2001
41
Benign metastasizing leiomyoma of the lung: a case report. (11155751)
2000
42
Benign metastasizing leiomyoma: a cytogenetically balanced but clonal disease. (10665925)
2000
43
Benign metastasizing leiomyoma with intracaval leiomyomatosis. (10844871)
2000
44
Benign metastasizing leiomyoma of the uterus: histologic and immunohistochemical characterization of primary and metastatic lesions. (10506455)
1999
45
Pulmonary leiomyomatosis in women after hysterectomy for uterine myoma. Benign metastasizing leiomyoma? (10439097)
1999
46
Immunohistological detection of estrogen and progesterone receptors in multiple and well differentiated leiomyomatous lung tumors in women with uterine leiomyomas (so-called benign metastasizing leiomyomas). A report on 5 cases. (8739468)
1996
47
Fine needle aspiration diagnosis of benign metastasizing leiomyoma of the lung. A case report. (8191830)
1994
48
Benign metastasizing leiomyoma. (3800475)
1987
49
Benign metastasizing leiomyoma. (6703252)
1984
50
Efficacy of oophorectomy in lymphangioleiomyomatosis and benign metastasizing leiomyoma. (7242600)
1981

Variations for Benign Metastasizing Leiomyoma

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Expression for genes affiliated with Benign Metastasizing Leiomyoma

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Search GEO for disease gene expression data for Benign Metastasizing Leiomyoma.

Pathways for genes affiliated with Benign Metastasizing Leiomyoma

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Pathways related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8CYP19A1, PGR
2
Show member pathways
9.7DES, VIM
39.3ACTC1, DES, VIM
4
Show member pathways
9.1DES, KRT7, VIM
59.0BCL2, MIR221, VIM
68.7ACTC1, DES, KRT7, VIM

GO Terms for genes affiliated with Benign Metastasizing Leiomyoma

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Cellular components related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.4DES, VIM
2intermediate filamentGO:00058829.1DES, KRT7, VIM

Biological processes related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament organizationGO:00451099.4DES, VIM
2negative regulation of neuron projection developmentGO:00109779.2LGALS1, VIM
3muscle filament slidingGO:00300499.2ACTC1, DES, VIM

Sources for Benign Metastasizing Leiomyoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet