MCID: BNG041
MIFTS: 31

Benign Metastasizing Leiomyoma malady

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Benign Metastasizing Leiomyoma

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Aliases & Descriptions for Benign Metastasizing Leiomyoma:

Name: Benign Metastasizing Leiomyoma 48
 
Benign Metastasizing Leiomyoma of Uterus 68

Classifications:



Summaries for Benign Metastasizing Leiomyoma

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MalaCards based summary: Benign Metastasizing Leiomyoma, also known as benign metastasizing leiomyoma of uterus, is related to leiomyoma and xq12-q13.3 duplication syndrome. An important gene associated with Benign Metastasizing Leiomyoma is DES (Desmin), and among its related pathways are Ovarian Infertility Genes and Aurora B signaling. Affiliated tissues include uterus, lung and lymph node, and related mouse phenotypes are cardiovascular system and cellular.

Related Diseases for Benign Metastasizing Leiomyoma

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Diseases related to Benign Metastasizing Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 132)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyoma10.7
2xq12-q13.3 duplication syndrome10.5ACTC1, DES
3dysembryoplastic neuroepithelial tumor10.5DES, PGR
4her2-receptor positive breast cancer10.5CYP19A1, PGR
5intravascular fasciitis10.5ACTC1, DES
6malignant secondary hypertension10.5CYP19A1, PGR
7retroperitoneum carcinoma10.5CYP19A1, PGR
8simple partial epilepsy10.5ACTC1, PGR
9harding ataxia10.5DES, VIM
10pura syndrome10.5ACTC1, DES
11pleuropulmonary blastoma type 210.5ACTC1, DES
12absence of fingerprints congenital milia10.5DES, VIM
13allergic cutaneous vasculitis10.5CYP19A1, PGR
14pancreatic delta cell neoplasm10.5DES, VIM
15monophasic synovial sarcoma10.5DES, VIM
16bartholin's gland benign neoplasm10.4DES, VIM
17parovarian cyst10.4ACTC1, DES
18malignant adenofibroma10.4DES, VIM
19sclerosing liposarcoma10.4DES, VIM
20congenital structural myopathy10.4PGR, VIM
21extracranial neuroblastoma10.4PGR, VIM
22breast adenoma10.4CYP19A1, PGR
23postcricoid region cancer10.4ACTC1, PGR
24angora hair nevus10.4DES, VIM
25gangliocytoma10.4DES, VIM
26benign mesenchymoma10.4PGR, VIM
27female reproductive endometrioid cancer10.4PGR, VIM
28lymphangiomatosis10.4ACTC1, VIM
29myxoid liposarcoma of the ovary10.4ACTC1, VIM
30iridogoniodysgenesis and skeletal anomalies10.4ACTC1, VIM
31small intestinal sarcoma10.4ACTC1, PGR
32prolapse of lacrimal gland10.4CYP19A1, PGR
33emerinopathy10.4DES, VIM
34skin sarcoma10.4ACTC1, VIM
35orbit rhabdomyosarcoma10.4ACTC1, DES
36serous cystadenocarcinoma10.4PGR, VIM
37uterine body mixed cancer10.4BCL2, PGR
38vulvar alveolar soft part sarcoma10.4ACTC1, VIM
39eccrine papillary adenoma10.4ACTC1, VIM
40malignant peritoneal solitary fibrous tumor10.4ACTC1, VIM
41pineal parenchymal tumor of intermediate differenciation10.3ACTC1, VIM
42myoclonic cerebellar dyssynergia10.3CYP19A1, PGR
43ovarian cystadenocarcinoma10.3ACTC1, VIM
44vascular hemostatic disease10.3ACTC1, VIM
45rheumatic pulmonary valve disease10.3BCL2, PGR
46longitudinal vaginal septum10.3ACTC1, DES
47bladder colonic type adenocarcinoma10.3KRT7, PGR
48pancreatic serous cystic neoplasm10.3KRT7, PGR
49dens in dente and palatal invaginations10.3ACTC1, VIM
50infiltrative basal cell carcinoma10.3KRT7, PGR

Graphical network of the top 20 diseases related to Benign Metastasizing Leiomyoma:



Diseases related to benign metastasizing leiomyoma

Symptoms & Phenotypes for Benign Metastasizing Leiomyoma

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MGI Mouse Phenotypes related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.9ACTC1, BCL2, CYP19A1, DES, PGR, VIM
2MP:00053848.2ACTC1, BCL2, CYP19A1, DES, KRT7, PGR
3MP:00053767.3ACTC1, BCL2, CYP19A1, DES, KRT7, LGALS1
4MP:00053697.2ACTC1, BCL2, CYP19A1, DES, LGALS1, PGR

Drugs & Therapeutics for Benign Metastasizing Leiomyoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Establishment of Fibroid Tissue BankTerminatedNCT00710346

Search NIH Clinical Center for Benign Metastasizing Leiomyoma

Genetic Tests for Benign Metastasizing Leiomyoma

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Anatomical Context for Benign Metastasizing Leiomyoma

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MalaCards organs/tissues related to Benign Metastasizing Leiomyoma:

36
Uterus, Lung, Lymph node, Appendix, Ovary, Breast, Spinal cord

Publications for Benign Metastasizing Leiomyoma

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Articles related to Benign Metastasizing Leiomyoma:

(show top 50)    (show all 104)
idTitleAuthorsYear
1
A Case of Simultaneous Benign Metastasizing Leiomyomas and Disseminated Peritoneal Leiomyomatosis Following Endoscopic Power Morcellation for Uterine Disease. (27748666)
2017
2
A rare cause of miliary pattern and respiratory failure - Benign metastasizing leiomyoma. (27178355)
2016
3
Benign metastasizing leiomyoma in triple location: lungs, parametria and appendix. (27582687)
2016
4
Benign Metastasizing Leiomyoma. (27514603)
2016
5
Benign Metastasizing Leiomyoma. (27659239)
2016
6
Cystic Benign Metastasizing Leiomyoma of the Lung Mimicking Hydatid Cyst. (27631636)
2016
7
Treatment decision based on the biological behavior of pulmonary benign metastasizing leiomyoma. (27621897)
2016
8
Pulmonary benign metastasizing leiomyoma, a rare cause of pulmonary nodules. (26518660)
2015
9
Incidental Finding of Synchronous, Benign, Metastasizing Leiomyoma with Distinct Cytogenetics in the Lung and Uterus. (26244194)
2015
10
What are MRI findings of Spine Benign Metastasizing Leiomyoma? Case report with literature review. (25632838)
2015
11
Benign metastasizing leiomyoma of the cervical spine 31 years after uterine leiomyoma resection. (25953612)
2015
12
Pulmonary benign metastasizing leiomyoma from the uterine leiomyoma: a case report. (25774240)
2015
13
Benign metastasizing leiomyoma of the lung: A case report and literature review. (26171020)
2015
14
Pulmonary benign metastasizing leiomyoma: a case report and literature review. (24977035)
2014
15
Difficulty in complete transarterial embolization for pulmonary benign metastasizing leiomyoma with massive hemoptysis. (24272622)
2014
16
Iatrogenic exacerbation of pulmonary arteriovenous malformation in a patient with benign metastasizing leiomyoma. (25473552)
2014
17
Pulmonary Benign Metastasizing Leiomyoma: An Extremely Rare Case. (24715553)
2014
18
Case of concurrent benign metastasizing leiomyoma in the lung and retroperitoneum, with a focus on its etiology. (25131768)
2014
19
Incidental benign metastasizing leiomyoma in a patient with bone sarcoma: a case report. (25221682)
2014
20
Benign metastasizing leiomyoma: a rare type of lung metastases-two case reports and review of the literature. (24716049)
2014
21
Pulmonary benign metastasizing leiomyoma: a case report. (25400799)
2014
22
Solitary benign metastasizing leiomyoma: imaging features and pathological findings. (24831406)
2014
23
Benign metastasizing leiomyoma of the lung: report of a case. (23117336)
2013
24
A rare pancreatic tumor in a 52-year-old Chinese woman. Pancreatic benign metastasizing leiomyoma. (23333466)
2013
25
Elevated 99mTc 3PRGD2 activity in benign metastasizing leiomyoma. (23334126)
2013
26
Benign metastasizing leiomyoma : Case report and review of the literature. (23903362)
2013
27
An undescribed coexistence of benign metastasizing leiomyoma in the lung with serous borderline tumor of the ovary. (23781598)
2013
28
Successful treatment of benign metastasizing leiomyoma with oral alternated chemotherapeutic agents. (24065503)
2013
29
Benign metastasizing leiomyoma of the lung with spontaneous pneumothorax. (25360407)
2013
30
Pulmonary benign metastasizing leiomyoma: report of three cases. (24139514)
2013
31
Novel hormone treatment of benign metastasizing leiomyoma: an analysis of five cases and literature review. (23465706)
2013
32
Pulmonary benign metastasizing leiomyoma from uterine leiomyoma. (23866077)
2013
33
Benign metastasizing leiomyoma of the lung. (24134076)
2013
34
Benign metastasizing leiomyoma: a rare cause of multiple pulmonary nodules. (22632533)
2012
35
Pulmonary benign metastasizing leiomyoma: a case report and review of the literature. (23234399)
2012
36
Benign metastasizing leiomyoma. (21566534)
2012
37
Genomic imbalances in benign metastasizing leiomyoma: characterization by conventional karyotypic, fluorescence in situ hybridization, and whole genome SNP array analysis. (22682624)
2012
38
Multifocal osteolytic lesions within lumbar spine in a middle-aged Chinese woman: a benign metastasizing leiomyoma? (21857396)
2012
39
Favorable response to antigonadal therapy for a benign metastasizing leiomyoma. (22270431)
2012
40
Benign metastasizing leiomyoma of the lung. (21959195)
2012
41
FDG-PET/CT finding of benign metastasizing leiomyoma of the lung. (23986835)
2012
42
Pulmonary benign metastasizing leiomyoma: case report and review of the literature. (22905478)
2012
43
Benign metastasizing leiomyoma with multiple lymph node metastasis: a case report. (21811430)
2011
44
Pulmonary and retroperitoneal benign metastasizing leiomyoma. (22384439)
2011
45
Clinical benefit of endocrine therapy for benign metastasizing leiomyoma. (21161313)
2011
46
Benign metastasizing leiomyoma of the lung with malignant transformation mimicking mediastinal tumor. (21872133)
2011
47
Benign metastasizing leiomyoma presenting as cystic lung disease: a diagnostic pitfall. (22014060)
2011
48
Serial spread of benign metastasizing leiomyoma to the thoracic spine. (21658956)
2011
49
Benign metastasizing leiomyoma - case report and review of literature. (21835535)
2011
50
Benign metastasizing leiomyoma of external iliac vessels: an unusual case report. (20800337)
2011

Variations for Benign Metastasizing Leiomyoma

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Expression for genes affiliated with Benign Metastasizing Leiomyoma

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Search GEO for disease gene expression data for Benign Metastasizing Leiomyoma.

Pathways for genes affiliated with Benign Metastasizing Leiomyoma

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Pathways related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8CYP19A1, PGR
2
Show member pathways
9.7DES, VIM
39.3ACTC1, DES, VIM
4
Show member pathways
9.1DES, KRT7, VIM
59.0BCL2, MIR221, VIM
68.7ACTC1, DES, KRT7, VIM

GO Terms for genes affiliated with Benign Metastasizing Leiomyoma

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Cellular components related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.7DES, VIM
2intermediate filamentGO:00058829.5DES, KRT7, VIM

Biological processes related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament organizationGO:004510910.2DES, VIM
2muscle filament slidingGO:00300499.7ACTC1, DES, VIM
3negative regulation of neuron projection developmentGO:00109779.2LGALS1, VIM

Sources for Benign Metastasizing Leiomyoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet