MCID: BNG041
MIFTS: 29

Benign Metastasizing Leiomyoma malady

Rare diseases, Cancer diseases categories

Aliases & Classifications for Benign Metastasizing Leiomyoma

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Aliases & Descriptions for Benign Metastasizing Leiomyoma:

Name: Benign Metastasizing Leiomyoma 45
 
Benign Metastasizing Leiomyoma of Uterus 65


Classifications:



Summaries for Benign Metastasizing Leiomyoma

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MalaCards based summary: Benign Metastasizing Leiomyoma, also known as benign metastasizing leiomyoma of uterus, is related to leiomyomatosis and leiomyoma. An important gene associated with Benign Metastasizing Leiomyoma is DES (Desmin), and among its related pathways are Ovarian Infertility Genes and Aurora B signaling. Affiliated tissues include uterus, lung and ovary, and related mouse phenotypes are cardiovascular system and behavior/neurological.

Related Diseases for Benign Metastasizing Leiomyoma

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Diseases related to Benign Metastasizing Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 140)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyomatosis30.6ACTC1, CYP19A1, DES, PGR, VIM
2leiomyoma11.2
3lymphangioleiomyomatosis10.5
4intravenous leiomyomatosis10.5
5acute laryngopharyngitis10.3DES, PGR
6spigelian hernia-cryptorchidism syndrome10.3ACTC1, DES
7necrotizing fasciitis10.3ACTC1, DES
8adolescence-adult electroclinical syndrome10.2DES, PGR
9cowden disease10.2ACTC1, PGR
10germ cell and embryonal cancer10.2CYP19A1, PGR
11subclavian steal syndrome10.2CYP19A1, PGR
12microscopic colitis10.2ACTC1, PGR
13spinocerebellar ataxia10.2BCL2, DES
14endometriosis in scar of skin10.2CYP19A1, PGR
15adenosarcoma of the uterus10.2CYP19A1, PGR
16pulmonary venous return anomaly10.2ACTC1, DES
17autosomal dominant charcot-marie-tooth disease type 2a210.2ACTC1, DES
18lung cancer10.2
19myoma10.2
20arteriovenous malformation10.2
21mediastinitis10.2
22pancreatitis10.2
23pneumothorax10.2
24sarcoma10.2
25pulmonary arteriovenous malformation10.2
26infantile free sialic acid storage disease10.2DES, VIM
27uveal diseases10.2CYP19A1, DES
28pituitary hypoplasia10.2ACTC1, PGR
29cervical mucinous adenocarcinoma10.2BCL2, PGR
30absence of fingerprints congenital milia10.2DES, VIM
31epithelioid cell synovial sarcoma10.2DES, VIM
32non-proliferative fibrocystic change of the breast10.2ACTC1, DES
33uterine corpus serous adenocarcinoma10.2DES, VIM
34rete ovarii adenoma10.2ACTC1, DES
35breast myofibroblastoma10.2PGR, VIM
36spindle cell liposarcoma10.2DES, VIM
37pancreatic colloid cystadenoma10.2DES, VIM
38primary hypertrophic osteoarthropathy10.2PGR, VIM
39suppurative cholangitis10.2BCL2, PGR
40her2-receptor positive breast cancer10.2CYP19A1, PGR
41vulvar syringoma10.2DES, VIM
42botulism10.2ACTC1, DES
43lung leiomyosarcoma10.2ACTC1, PGR
44familial syringomyelia10.2DES, VIM
45mesenchymoma10.2DES, VIM
46lymphangiomatosis10.2ACTC1, VIM
47gastric signet ring cell adenocarcinoma10.2ACTC1, VIM
48iodine antenatal infection10.2ACTC1, VIM
49cervical verrucous carcinoma10.2DES, VIM
50prostatic urethral cancer10.2CYP19A1, PGR

Graphical network of the top 20 diseases related to Benign Metastasizing Leiomyoma:



Diseases related to benign metastasizing leiomyoma

Symptoms for Benign Metastasizing Leiomyoma

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Drugs & Therapeutics for Benign Metastasizing Leiomyoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Establishment of Fibroid Tissue BankCompletedNCT00710346

Search NIH Clinical Center for Benign Metastasizing Leiomyoma

Genetic Tests for Benign Metastasizing Leiomyoma

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Anatomical Context for Benign Metastasizing Leiomyoma

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MalaCards organs/tissues related to Benign Metastasizing Leiomyoma:

33
Uterus, Lung, Ovary, Breast, Bone, Lymph node, Spinal cord

Animal Models for Benign Metastasizing Leiomyoma or affiliated genes

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MGI Mouse Phenotypes related to Benign Metastasizing Leiomyoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.9ACTC1, BCL2, CYP19A1, DES, PGR, VIM
2MP:00053867.6BCL2, CYP19A1, DES, LGALS1, PGR, VIM
3MP:00053697.3ACTC1, BCL2, CYP19A1, DES, LGALS1, PGR

Publications for Benign Metastasizing Leiomyoma

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Articles related to Benign Metastasizing Leiomyoma:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Pulmonary benign metastasizing leiomyoma, a rare cause of pulmonary nodules. (26518660)
2015
2
Incidental Finding of Synchronous, Benign, Metastasizing Leiomyoma with Distinct Cytogenetics in the Lung and Uterus. (26244194)
2015
3
What are MRI findings of Spine Benign Metastasizing Leiomyoma? Case report with literature review. (25632838)
2015
4
Incidental benign metastasizing leiomyoma in a patient with bone sarcoma: a case report. (25221682)
2014
5
Pulmonary benign metastasizing leiomyoma: a case report and literature review. (24977035)
2014
6
Difficulty in complete transarterial embolization for pulmonary benign metastasizing leiomyoma with massive hemoptysis. (24272622)
2014
7
Benign metastasizing leiomyoma of the lung: report of a case. (23117336)
2013
8
Benign metastasizing leiomyoma of the lung with spontaneous pneumothorax. (25360407)
2013
9
A rare pancreatic tumor in a 52-year-old Chinese woman. Pancreatic benign metastasizing leiomyoma. (23333466)
2013
10
Pulmonary benign metastasizing leiomyoma: report of three cases. (24139514)
2013
11
Novel hormone treatment of benign metastasizing leiomyoma: an analysis of five cases and literature review. (23465706)
2013
12
Elevated 99mTc 3PRGD2 activity in benign metastasizing leiomyoma. (23334126)
2013
13
Benign metastasizing leiomyoma : Case report and review of the literature. (23903362)
2013
14
Multifocal osteolytic lesions within lumbar spine in a middle-aged Chinese woman: a benign metastasizing leiomyoma? (21857396)
2012
15
Benign metastasizing leiomyoma: a rare cause of multiple pulmonary nodules. (22632533)
2012
16
Favorable response to antigonadal therapy for a benign metastasizing leiomyoma. (22270431)
2012
17
Pulmonary benign metastasizing leiomyoma: a case report and review of the literature. (23234399)
2012
18
Benign metastasizing leiomyoma of the lung. (21959195)
2012
19
Benign metastasizing leiomyoma with multiple lymph node metastasis: a case report. (21811430)
2011
20
Serial spread of benign metastasizing leiomyoma to the thoracic spine. (21658956)
2011
21
Pulmonary and retroperitoneal benign metastasizing leiomyoma. (22384439)
2011
22
Benign metastasizing leiomyoma - case report and review of literature. (21835535)
2011
23
Benign metastasizing leiomyoma identified using 18F-FDG PET/CT. (20435308)
2010
24
Pathogenesis of benign metastasizing leiomyoma: a review. (20214834)
2010
25
Benign metastasizing leiomyoma: report of two cases and literature review. (21163149)
2010
26
Benign metastasizing leiomyoma: a rare metastatic lesion in the right ventricle. (20103256)
2010
27
Benign metastasizing leiomyoma of the lung: PET findings. (19242303)
2009
28
A case of benign metastasizing leiomyoma treated by surgical castration followed by an aromatase inhibitor, anastrozole. (18523791)
2009
29
Intravenous leiomyomatosis of the uterus with pulmonary metastases or a case with benign metastasizing leiomyoma? (19331193)
2009
30
Benign metastasizing leiomyoma: report of 2 cases and review of the literature. (19771765)
2009
31
Recurrent benign metastasizing leiomyoma after hysterectomy and bilateral salpingo-oophorectomy. (18259767)
2008
32
Benign metastasizing leiomyoma of the lung: clinicopathologic, immunohistochemical, and micro-RNA analyses. (18382364)
2008
33
Benign metastasizing leiomyoma of the uterus. (17198463)
2007
34
Benign metastasizing leiomyoma: clonality, telomere length and clinicopathologic analysis. (16357844)
2006
35
Benign metastasizing leiomyoma responsive to megestrol: case report and review of the literature. (16343217)
2005
36
Pulmonary benign metastasizing leiomyoma from the uterus in a postmenopausal woman: report of a case. (14714229)
2004
37
Benign metastasizing leiomyoma to skull base and spine: a report of two cases. (12860509)
2003
38
Benign metastasizing leiomyoma causing spinal cord compression. (14670684)
2003
39
Benign metastasizing leiomyoma in the lung: a case report. (12440822)
2002
40
Benign metastasizing leiomyoma of the lung: a case report. (11155751)
2000
41
Benign metastasizing leiomyoma of the uterus: documentation of clinical, immunohistochemical and lectin-histochemical data of ten cases. (11037349)
2000
42
Benign metastasizing leiomyoma of the uterus: histologic and immunohistochemical characterization of primary and metastatic lesions. (10506455)
1999
43
Pulmonary leiomyomatosis in women after hysterectomy for uterine myoma. Benign metastasizing leiomyoma? (10439097)
1999
44
Benign metastasizing leiomyoma in the lung. (9599398)
1998
45
Immunohistological detection of estrogen and progesterone receptors in multiple and well differentiated leiomyomatous lung tumors in women with uterine leiomyomas (so-called benign metastasizing leiomyomas). A report on 5 cases. (8739468)
1996
46
Efficacy of antiestrogen treatment in a benign metastasizing leiomyoma with paraneoplastic estradiol production. (21594362)
1996
47
Fine needle aspiration diagnosis of benign metastasizing leiomyoma of the lung. A case report. (8191830)
1994
48
Use of LHRH analogue to obtain reversible castration in a patient with benign metastasizing leiomyoma. (3085706)
1986
49
Benign metastasizing leiomyoma. (6703252)
1984
50
Efficacy of oophorectomy in lymphangioleiomyomatosis and benign metastasizing leiomyoma. (7242600)
1981

Variations for Benign Metastasizing Leiomyoma

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Expression for genes affiliated with Benign Metastasizing Leiomyoma

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Search GEO for disease gene expression data for Benign Metastasizing Leiomyoma.

Pathways for genes affiliated with Benign Metastasizing Leiomyoma

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Pathways related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8CYP19A1, PGR
2
Show member pathways
9.6DES, VIM
3
Show member pathways
9.2ACTC1, DES, VIM
4
Show member pathways
9.0DES, KRT7, VIM
59.0BCL2, MIR221, VIM
68.6ACTC1, DES, KRT7, VIM

GO Terms for genes affiliated with Benign Metastasizing Leiomyoma

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Cellular components related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.0DES, KRT7, VIM

Biological processes related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron projection developmentGO:00109779.5LGALS1, VIM
2muscle filament slidingGO:00300499.2ACTC1, DES, VIM
3apoptotic processGO:00069158.0ACTC1, BCL2, LGALS1, VIM

Molecular functions related to Benign Metastasizing Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:00051989.0DES, KRT7, VIM

Sources for Benign Metastasizing Leiomyoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet