MCID: BNG016
MIFTS: 44

Benign Migratory Glossitis malady

Gastrointestinal diseases category

Summaries for Benign Migratory Glossitis

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42NIH Rare Diseases, 63Wikipedia, 46OMIM, 32MalaCards
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NIH Rare Diseases:42 Geographic tongue is a condition that causes lesions on the tongue that resemble psoriasis of the skin. the lesions may also occasionally occur in the mucosa of the mouth and labia; this condition is called areata migrans. the lesions typically disappear from one area and move to another. last updated: 7/9/2013

MalaCards: Benign Migratory Glossitis, also known as geographic tongue, is related to skin disease and psoriasis. An important gene associated with Benign Migratory Glossitis is IL1B (interleukin 1, beta), and among its related pathways are Legionellosis and Tuberculosis. The compounds troglitazone and gm-csf have been mentioned in the context of this disorder. Affiliated tissues include tongue and skin.

Wikipedia:63 Geographic tongue (also known as benign migratory glossitis,BMG, erythema migrans,erythema migrans... more...

Description from OMIM:46 137400

Aliases & Classifications for Benign Migratory Glossitis

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8Disease Ontology, 42NIH Rare Diseases, 60UMLS, 27ICD9CM, 34MeSH, 56SNOMED-CT, 46OMIM, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

benign migratory glossitis 8 42
geographic tongue 8 42
erythema migrans 42 60
glossitis areata exfoliativa 8
glossitis, benign migratory 60
ectopic geographic tongue 42
premature cardiac complex 60
pityriasis linguae 8


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Disease Ontology8 DOID:1455
ICD9CM27 529.1
MeSH34 D005929
OMIM46 137400
NCIt39 C84588
ICD1025 K14.1

Related Diseases for Benign Migratory Glossitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Benign Migratory Glossitis:



Diseases related to benign migratory glossitis

Clinical Features for Benign Migratory Glossitis

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46OMIM
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Clinical features from OMIM:

137400

Drugs & Therapeutics for Benign Migratory Glossitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Benign Migratory Glossitis

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Genetic Tests for Benign Migratory Glossitis

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Anatomical Context for Benign Migratory Glossitis

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32MalaCards
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MalaCards organs/tissues related to Benign Migratory Glossitis:

32
Tongue, Skin

Animal Models for Benign Migratory Glossitis or affiliated genes

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Publications for Benign Migratory Glossitis

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50PubMed
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Articles related to Benign Migratory Glossitis:

(show all 24)
idTitleAuthorsYear
1
Benign migratory glossitis. (24413515)
2013
2
Benign migratory glossitis with fissured tongue. (22918106)
2012
3
Taste evaluation in adolescents and pediatric patients with benign migratory glossitis. (21802154)
2011
4
Predisposition of allergy in patients with benign migratory glossitis. (20674406)
2010
5
Oral pathology. Benign migratory glossitis. (20806635)
2010
6
The prevalence and risk factors associated with benign migratory glossitis lesions in 7619 Turkish dental outpatients. (19138635)
2009
7
Unusual coexistence of oral lymphoepithelial cyst and benign migratory glossitis. (19575124)
2009
8
Successful treatment with cyclosporin administration for persistent benign migratory glossitis. (17408445)
2007
9
Investigation of functional gene polymorphisms: IL-1B, IL-6 and TNFA in benign migratory glossitis in Brazilian individuals. (17850436)
2007
10
Painful geographic tongue (benign migratory glossitis) in a child. (15482313)
2004
11
Benign migratory glossitis or geographic tongue: an enigmatic oral lesion. (12517366)
2002
12
Both psoriasis and benign migratory glossitis are associated with HLA-Cw6. (8949427)
1996
13
Symptomatic benign migratory glossitis: report of two cases and literature review. (1303549)
1992
14
Case #5. Benign migratory glossitis. (1887082)
1991
15
Differential diagnosis in dentistry: benign migratory glossitis. (3216128)
1988
16
Benign migratory glossitis in patients with juvenile diabetes. (3468467)
1987
17
Salicylic acid in alcohol in the treatment of benign superficial migratory glossitis. (6592304)
1984
18
Benign migratory glossitis and allergy. (6963406)
1982
19
Benign migratory glossitis--a cause for worry? (7334963)
1981
20
Atypical benign migratory glossitis. Report of a case with histologic and electron microscopic evaluations. (1069222)
1976
21
Benign migratory glossitis. (1054669)
1975
22
Benign migratory glossitis associated with lichen planus. (4524269)
1974
23
Hereditary component in the etiology of benign migratory glossitis. (5016506)
1972
24
The occurrence of Fordyce spots, benign migratory glossitis, median rhomboid glossitis, and fissured tongue in 2,478 dental patients. (13088005)
1953

Genetic Variations for Benign Migratory Glossitis

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Expression for genes affiliated with Benign Migratory Glossitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Benign Migratory Glossitis

Search GEO for disease gene expression data for Benign Migratory Glossitis.

Pathways for genes affiliated with Benign Migratory Glossitis

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29KEGG, 12EMD Millipore, 52R&D Systems, 51QIAGEN, 37NCBI BioSystems Database, 53Reactome
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Pathways related to Benign Migratory Glossitis according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0IL1B
29.7TNF
39.3IL1B, IL6
4
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9.3IL6, IL1B
59.3IL6, IL1B
6
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9.3IL1B, IL6
79.3IL6, IL1B
89.1IL1B, TNF
99.1IL1B, TNF
109.1IL1B, TNF
119.1IL1B, TNF
129.0TNF, IL6
139.0IL6, TNF
14
Hide members
8.5IL6, IL1B, TNF
15
Hide members
8.5TNF, IL1B, IL6
16
Hide members
8.5TNF, IL1B, IL6
17
Hide members
8.5IL6, IL1B, TNF
188.5IL6, IL1B, TNF
198.5TNF, IL1B, IL6
208.5TNF, IL1B, IL6
218.5TNF, IL1B, IL6
22
Immune response Bacterial infections in normal airways
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8.5IL6, IL1B, TNF
23
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8.5TNF, IL1B, IL6
248.5TNF, IL1B, IL6
258.5TNF, IL1B, IL6
26
Hide members
8.5TNF, IL1B, IL6
27
Hide members
8.5IL6, IL1B, TNF
28
Hide members
8.5TNF, IL1B, IL6
298.5IL6, IL1B, TNF
30
Development PDGF signaling via STATs and NF-kB
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8.5IL6, IL1B, TNF
318.5TNF, IL1B, IL6
328.5TNF, IL1B, IL6
338.5IL6, IL1B, TNF
34
Hide members
8.5TNF, IL1B, IL6

Compounds for genes affiliated with Benign Migratory Glossitis

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44Novoseek, 28IUPHAR, 59Tocris Bioscience, 11DrugBank, 49PharmGKB, 24HMDB
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Compounds related to Benign Migratory Glossitis according to GeneCards/GeneDecks:

(show top 50)    (show all 85)
idCompoundScoreTop Affiliating Genes
1troglitazone44 28 59 1113.3IL1B
2gm-csf44 2811.1TNF
3actinomycin4410.1IL1B
4muramyl tripeptide phosphatidylethanolamine449.7IL6, IL1B
5turpentine449.7IL1B, IL6
6bucillamine449.6IL6, IL1B
7hbd2449.5IL1B, IL6
8n,n-dimethylsphingosine44 5910.4IL1B, TNF
9tocilizumab44 1110.4TNF, IL6
10abatacept44 1110.4TNF, IL6
11cicaprost44 2810.4IL1B, TNF
12cdp571449.4IL6, TNF
13toxin-1449.3TNF, IL1B
14helenalin449.2IL1B, IL6
15gold sodium thiomalate449.1IL1B, TNF
16anakinra44 1110.0IL6, IL1B, TNF
17taurine chloramine449.0TNF, IL1B, IL6
18vesnarinone449.0TNF, IL1B, IL6
19mip 1alpha449.0TNF, IL1B, IL6
20il-12449.0IL6, IL1B, TNF
21tpck449.0TNF, IL1B, IL6
22polymyxin b448.9IL6, IL1B, TNF
23groalpha448.9TNF, IL1B, IL6
24leflunomide49 44 1110.9TNF, IL1B, IL6
25triptolide448.9IL6, IL1B, TNF
26ciglitazone44 289.9TNF, IL1B, IL6
27lipoteichoic acid448.9IL6, IL1B, TNF
28polyinosinic-polycytidylic acid448.9IL6, IL1B, TNF
29etanercept44 49 1110.9TNF, IL1B, IL6
30poly(i-c)448.9IL6, IL1B, TNF
31il 10448.9IL6, IL1B, TNF
32infliximab44 49 1110.9TNF, IL1B, IL6
33peptidoglycan44 289.9IL6, IL1B, TNF
34ccl344 289.9IL6, IL1B, TNF
35neopterin448.9TNF, IL1B, IL6
3615-deoxy-delta-12,14-prostaglandin j2448.9IL6, IL1B, TNF
37pdtc448.9TNF, IL1B, IL6
38thalidomide44 49 59 1111.9IL6, IL1B, TNF
39anisomycin44 119.9IL6, IL1B, TNF
40leukotriene b444 59 2410.9IL6, IL1B, TNF
41sp 60012544 599.8IL6, IL1B, TNF
42tgf beta1448.8TNF, IL1B, IL6
43herbimycin a44 599.8IL6, IL1B, TNF
44curcumin448.8TNF, IL1B, IL6
45prostaglandin448.8IL6, IL1B, TNF
46calcitriol44 59 11 2411.7TNF, IL1B, IL6
47methotrexate44 49 1110.7IL6, IL1B, TNF
48rantes448.6IL6, IL1B, TNF
49indomethacin44 59 28 1111.5IL6, IL1B, TNF
50n acetylcysteine448.2IL6, IL1B, TNF

GO Terms for genes affiliated with Benign Migratory Glossitis

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16Gene Ontology
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Biological processes related to Benign Migratory Glossitis according to GeneCards/GeneDecks:

(show all 41)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of T cell proliferationGO:0421029.6IL1B, IL6
2sequestering of triglycerideGO:0307309.6IL1B, TNF
3positive regulation of calcidiol 1-monooxygenase activityGO:0605599.6IL1B, TNF
4positive regulation of heterotypic cell-cell adhesionGO:0341169.5IL1B, TNF
5positive regulation of fever generationGO:0316229.5IL1B, TNF
6positive regulation of chemokine biosynthetic processGO:0450809.5IL1B, TNF
7regulation of I-kappaB kinase/NF-kappaB cascadeGO:0431229.5IL1B, TNF
8positive regulation of membrane protein ectodomain proteolysisGO:0510449.5TNF, IL1B
9negative regulation of lipid catabolic processGO:0509959.5IL1B, TNF
10positive regulation of NF-kappaB import into nucleusGO:0423469.5TNF, IL1B
11negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.5IL1B, TNF
12lipopolysaccharide-mediated signaling pathwayGO:0316639.5IL1B, TNF
13positive regulation of mitosisGO:0458409.5IL1B, TNF
14cellular response to organic cyclic compoundGO:0714079.5TNF, IL1B
15protein kinase B signaling cascadeGO:0434919.5IL1B, TNF
16positive regulation of interferon-gamma productionGO:0327299.4IL1B, TNF
17epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.4TNF, IL6
18negative regulation of lipid storageGO:0108889.4TNF, IL6
19positive regulation of chemokine productionGO:0327229.4IL6, TNF
20positive regulation of JNK cascadeGO:0463309.4IL1B, TNF
21negative regulation of fat cell differentiationGO:0455999.4IL6, TNF
22defense response to Gram-positive bacteriumGO:0508309.3TNF, IL6
23positive regulation of smooth muscle cell proliferationGO:0486619.3IL6, TNF
24humoral immune responseGO:0069599.3IL6, TNF
25MAPK cascadeGO:0001659.3TNF, IL1B
26response to mechanical stimulusGO:0096129.3TNF, IL6
27positive regulation of peptidyl-serine phosphorylationGO:0331389.2IL6, TNF
28regulation of insulin secretionGO:0507969.2TNF, IL1B
29response to glucocorticoid stimulusGO:0513849.2IL6, TNF
30positive regulation of protein kinase B signaling cascadeGO:0518979.1IL6, TNF
31positive regulation of protein phosphorylationGO:0019349.0TNF, IL1B
32positive regulation of ERK1 and ERK2 cascadeGO:0703749.0IL6, TNF
33positive regulation of nitric oxide biosynthetic processGO:0454298.9IL6, IL1B, TNF
34positive regulation of interleukin-6 productionGO:0327558.9TNF, IL1B, IL6
35positive regulation of sequence-specific DNA binding transcription factor activityGO:0510918.9TNF, IL1B, IL6
36positive regulation of NF-kappaB transcription factor activityGO:0510928.9TNF, IL1B, IL6
37inflammatory responseGO:0069548.9TNF, IL1B, IL6
38negative regulation of cell proliferationGO:0082858.8TNF, IL1B, IL6
39activation of MAPK activityGO:0001878.8IL1B, TNF
40positive regulation of transcription, DNA-dependentGO:0458938.8TNF, IL1B, IL6
41positive regulation of transcription from RNA polymerase II promoterGO:0459448.5IL6, IL1B, TNF

Molecular functions related to Benign Migratory Glossitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:0051258.5IL6, IL1B, TNF

Products for genes affiliated with Benign Migratory Glossitis

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Sources for Benign Migratory Glossitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet