MCID: BRB001
MIFTS: 42

Beriberi malady

Rare diseases category

Summaries for Beriberi

About this section
Sources:
66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Wikipedia:66 \"Beri Beri\" redirects here. For the African ethnic group, please see Kanuri people more...

MalaCards: Beriberi, also known as thiamine deficiency, is related to wernicke-korsakoff syndrome and polyneuropathy. An important gene associated with Beriberi is TKT (transketolase), and among its related pathways is Metabolism. The drugs thiamine and thiamine mononitrate and the compounds thymine and pyrimidine have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and brain.

Aliases & Classifications for Beriberi

About this section
Sources:
9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 36MeSH, 41NCIt, 28ICD9CM, 26ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

beriberi 9 44 11 46 63
thiamine deficiency 44 46 63
vitamin b1 deficiency 44


External Ids:

Disease Ontology9 DOID:13725
MeSH36 D001602
NCIt41 C34418
ICD9CM28 265.0
ICD1026 E51, E51.1, E51.9

Related Diseases for Beriberi

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Graphical network of the top 20 diseases related to Beriberi:



Diseases related to beriberi

Symptoms for Beriberi

About this section

Drugs & Therapeutics for Beriberi

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Beriberi

Drug clinical trials:

Search ClinicalTrials for Beriberi

Search NIH Clinical Center for Beriberi

Search CenterWatch for Beriberi

Inferred drug relations via UMLS63/NDF-RT42:

Genetic Tests for Beriberi

About this section

Anatomical Context for Beriberi

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Beriberi:

34
Heart, Liver, Brain, Endothelial

Animal Models for Beriberi or affiliated genes

About this section

Publications for Beriberi

About this section
Sources:
53PubMed
See all sources

Articles related to Beriberi:

(show top 50)    (show all 241)
idTitleAuthorsYear
1
Use of central venous saturation monitoring in a patient with pediatric cardiac beriberi. (24303502)
2013
2
Adolphe Vorderman's 1897 study on beriberi: an example of scrupulous efforts to avoid bias. (23481433)
2013
3
Case of beriberi showing improved cerebral blood flow after thiamine treatment. (22998382)
2012
4
Severe encephalopathy, lactic acidosis, vegetative instability and neuropathy with 5-Fluorouracil treatment - pyrimidine degradation defect or beriberi? (21941485)
2011
5
Outbreak of beriberi in the state of MaranhALo, Brazil: revisiting the mycotoxin aetiologic hypothesis. (20305104)
2010
6
Rapidly progressive polyneuropathy due to dry beriberi in a man: a case report. (21176139)
2010
7
Outbreak of beriberi in a prison in CA'te d'Ivoire. (17974361)
2007
8
The great disease enemy, Kak'ke (beriberi) and the Imperial Japanese Army. (16673750)
2006
9
Gastrointestinal beriberi: a previously unrecognized syndrome. (15583247)
2004
10
Postgastrectomy polyneuropathy with thiamine deficiency is identical to beriberi neuropathy. (15561484)
2004
11
Outbreak of beriberi among illegal mainland Chinese immigrants at a detention center in Taiwan. (12604765)
2003
12
Shoshin beriberi with vasospastic angina pectoris possible mechanism of mid-ventricular obstruction: possible mechanism of mid-ventricular obstruction. (12419944)
2002
13
Early recognition of acute cardiovascular beriberi by interpretation of hemodynamics. (11377164)
2001
14
Experimentally induced beriberi polyneuropathy in chickens. (7737017)
1995
15
A case of beriberi accompanying short bowel. (7754775)
1995
16
Cardiac beriberi (shoshin beriberi) caused by excessive intake of isotonic drink. (1414337)
1992
17
Shoshin beriberi in an infant of a thiamine-deficient mother. (1421919)
1992
18
Clinical diagnosis of cardiac beriberi. (2305319)
1990
19
Beriberi secondary to tooth decay. (2567829)
1989
20
Beriberi--another Asia-Pacific connection. (3052543)
1988
21
Neuropathic beriberi and carbamazepine. (2844112)
1988
22
Shoshin beriberi: an underdiagnosed condition? (3771918)
1986
23
Thiamine-dependent beriberi. (3969105)
1985
24
Shoshin beriberi: a rare diagnostic problem. (6508970)
1984
25
The beriberi analogy to myocardial infarction. (6341793)
1983
26
Shoshin beriberi. (6952848)
1982
27
Shoshin beriberi. (6123912)
1982
28
Alcoholic cardiac beriberi. (6807459)
1982
29
A protection against beriberi. (7357326)
1980
30
Swellengrebel lecture. Beriberi. (7210153)
1980
31
Atrophic beriberi. A complication of jejunoileal bypass surgery for morbid obesity. (210663)
1978
32
A possible case of beriberi heart failure in a chronic hemodialyzed patient. (124021)
1975
33
Cardiac beriberi: two modes of presentation. (5571454)
1971
34
Persistence of low cardiac output after relief of high output by thiamine in a case of alcoholic beriberi and cardiac myopathy. (5426825)
1970
35
Blood transketolase activity in beriberi heart disease. A useful diagnostic index. (5694078)
1968
36
Therapeutic use of vitamin B1 in diseases other than beriberi. (14009959)
1962
37
Beriberi heart disease in the elderly patient. (14400982)
1960
38
Beriberi heart disease. (13524621)
1958
39
John Blackall's observations on the relation between nutritional deprivation and wet beriberi. (13348836)
1956
40
POLYNEURITIS beriberi due to a deficiency of vitamin B1. (14371243)
1955
41
Beriberi heart disease. (13097096)
1953
42
The world beriberi problem today. (13130700)
1953
43
Cardiac beriberi simulating arteriosclerotic heart disease. (14885076)
1951
44
Artificial enrichment of white rice as a solution to endemic beriberi; preliminary report of field trials. (18140048)
1949
45
Cardiovascular manifestations of beriberi based on a study of ten patients. (15391541)
1949
46
Beriberi heart disease. (21017512)
1946
47
THE EFFECT OF COCARBOXYLASE UPON METABOLISM AND NEURO-PSYCHIATRIC PHENOMENA IN PELLAGRINS WITH BERIBERI. (17829078)
1939
48
Beriberi and other Food-deficiency Diseases in New-foundland and Labrador. (20475070)
1930
49
Studies on beriberi: VIII. The relationship of beriberi to glands of internal secretion. (16993223)
1914
50
UNCURED RICE AS A CAUSE OF BERIBERI. (20764688)
1909

Variations for Beriberi

About this section

Expression for genes affiliated with Beriberi

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Beriberi

Search GEO for disease gene expression data for Beriberi.

Pathways for genes affiliated with Beriberi

About this section
Sources:
51PathCards, 56Reactome, 31KEGG
See all sources

Pathways related to Beriberi according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
8.0TKT, DPYS, TPK1, HACL1

Compounds for genes affiliated with Beriberi

About this section
Sources:
46Novoseek, 25HMDB, 3BitterDB, 12DrugBank
See all sources

Compounds related to Beriberi according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
1thymine46 2510.5TKT, DPYS
2pyrimidine46 2510.4TKT, DPYS
3thiamine monophosphate46 2510.4TPK1, TKT
4cytosine46 2510.3DPYS, TKT
5thiamin diphosphate469.3TPK1, TKT
6thymidine46 2510.3TKT, DPYS
7alpha-ketoglutarate469.2TKT, TPK1
8pyruvate469.0TKT, TPK1
95fluorouracil469.0TKT, DPYS
10thiamine pyrophosphate46 259.9TKT, TPK1, HACL1
11thiamine46 3 25 1211.8TKT, TPK1, HACL1
12magnesium46 25 1210.8HACL1, TPK1, TKT

GO Terms for genes affiliated with Beriberi

About this section
Sources:
17Gene Ontology
See all sources

Cellular components related to Beriberi according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:0057779.1TKT, HACL1
2cytosolGO:0058298.5TKT, DPYS, TPK1

Biological processes related to Beriberi according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:0442818.0TKT, DPYS, TPK1, HACL1

Molecular functions related to Beriberi according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cofactor bindingGO:0480379.4TKT, HACL1

Products for genes affiliated with Beriberi

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Beriberi

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet