MCID: BRB001
MIFTS: 43

Beriberi malady

Metabolic diseases category

Summaries for Beriberi

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63Wikipedia, 32MalaCards
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Wikipedia:63 Beriberi refers to a cluster of symptoms caused primarily by a nutritional deficit in Vitamin B1... more...

MalaCards: Beriberi, also known as thiamine deficiency, is related to wernicke-korsakoff syndrome and polyneuropathy. An important gene associated with Beriberi is DPYS (dihydropyrimidinase). The drugs thiamine and thiamine mononitrate and the compounds thymine and pyrimidine have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and liver.

Aliases & Classifications for Beriberi

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 34MeSH, 39NCIt, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Metabolic diseases


Aliases & Descriptions:

beriberi 8 42 10 44 60
thiamine deficiency 42 44 60
vitamin b1 deficiency 42


External Ids:

Disease Ontology8 DOID:13725
MeSH34 D001602
NCIt39 C34418
ICD9CM27 265.0
ICD1025 E51, E51.1, E51.9

Related Diseases for Beriberi

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Beriberi:



Diseases related to beriberi

Clinical Features for Beriberi

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Drugs & Therapeutics for Beriberi

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Beriberi

Drug clinical trials:

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Search NIH Clinical Center for Beriberi

Search CenterWatch for Beriberi

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Beriberi

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Anatomical Context for Beriberi

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Sources:
32MalaCards
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MalaCards organs/tissues related to Beriberi:

32
Heart, Brain, Liver, Endothelial

Animal Models for Beriberi or affiliated genes

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Publications for Beriberi

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Sources:
50PubMed
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Articles related to Beriberi:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Use of central venous saturation monitoring in a patient with pediatric cardiac beriberi. (24303502)
2013
2
Beriberi in a dialysis patient: do we need more thiamine? (23399344)
2013
3
Subacute myeloa89optic neuropathy, beriberi, and HTLVa89Ia89associated myelopathy: elucidation of some neurological diseases in Japan. (23222550)
2012
4
Outbreak of beriberi among African Union troops in Mogadishu, Somalia. (22205947)
2011
5
Cardiovascular magnetic resonance in wet beriberi. (21838901)
2011
6
Rapidly progressive polyneuropathy due to dry beriberi in a man: a case report. (21176139)
2010
7
Production of citreoviridin by Penicillium citreonigrum strains associated with rice consumption and beriberi cases in the MaranhALo State, Brazil. (19802756)
2010
8
Was it really beriberi? (19608772)
2009
9
Outbreak of beriberi in a prison in CA'te d'Ivoire. (17974361)
2007
10
Beriberi after gastric bypass surgery in adolescence. (15289782)
2004
11
Development of beriberi heart disease 20 years after gastrojejunostomy. (12893406)
2003
12
Bariatric beriberi. (12082878)
2002
13
Iatrogenic fulminant beriberi. (7603247)
1995
14
Hypothesis on cellular ATP depletion and adenosine release as causes of heart failure and vasodilatation in cardiovascular beriberi. (8569549)
1995
15
Shoshin beriberi in a patient with human immunodeficiency virus infection. (8294635)
1993
16
Cardiac beriberi (shoshin beriberi) caused by excessive intake of isotonic drink. (1414337)
1992
17
Shoshin beriberi in an AIDS patient with end-stage renal disease. (10969632)
1992
18
Acute pernicious beriberi in a patient receiving parenteral nutrition. A case report. (2499068)
1989
19
Beriberi in a Southeast Asian adolescent. (2916504)
1989
20
Beriberi--another Asia-Pacific connection. (3052543)
1988
21
Of birds and B1: the story of beriberi. (3289589)
1988
22
Shoshin beriberi. (3611505)
1987
23
Cardiac beriberi. A report of 4 cases. (3616818)
1987
24
Acute renal failure in fulminating beriberi. (3818119)
1986
25
Beriberi heart disease. A case report describing the haemodynamic features. (4035486)
1985
26
Alcoholic cardiac beriberi. (6807459)
1982
27
Beriberi caused by antithiamin factors in food and its prevention. (7044221)
1982
28
Alcoholic cardiac beriberi. (6805710)
1982
29
The haemodynamic, histopathological and hormonal features of alcoholic cardiac beriberi. (7342167)
1981
30
Shoshin beriberi with severe metabolic acidosis. (7280764)
1981
31
Swellengrebel lecture. Beriberi. (7210153)
1980
32
Atrophic beriberi. A complication of jejunoileal bypass surgery for morbid obesity. (210663)
1978
33
Dry beriberi in a slimmer. (589393)
1977
34
A possible case of beriberi heart failure in a chronic hemodialyzed patient. (124021)
1975
35
Serial electrocardiographic changes in cardiac beriberi. (4273284)
1974
36
Cardiovascular beriberi. (5056853)
1972
37
Beriberi in Bethnal Green. (5572400)
1971
38
Thiamine deficiency and beriberi heart disease. (5943852)
1966
39
EXPERIMENTAL STUDIES ON THE BERIBERI HEART. III. CORRECT TREATMENT DOSES OF THIAMINE FOR THE BERIBERI HEART DISEASE AND EFFECTS OF VITACAMPHER AND NOREPHINEPHRINE. (14153990)
1964
40
THREE UNEXPECTED PRODUCTS OF PEROXIDASE REACTION; BRAIN SITE OF LESION, BERIBERI POISON AND NEW DISEASE. (14216980)
1964
41
Beriberi of mother and child in Burma. (13635856)
1958
42
John Blackall's observations on the relation between nutritional deprivation and wet beriberi. (13348836)
1956
43
The electrocardiogram in oriental beriberi. (13216952)
1954
44
BERIBERI in Japan. (14780591)
1950
45
Artificial enrichment of white rice as a solution to endemic beriberi; preliminary report of field trials. (18140048)
1949
46
Cerebral beriberi (Wernicke's encephalopathy); review of 52 cases in a Singapore prisoner-of-war hospital. (20278697)
1947
47
A Fatal Case of Beriberi in a Child in England. (21032336)
1946
48
The zinc content of epidermal structures in beriberi. (16746926)
1939
49
Studies on beriberi: VIII. The relationship of beriberi to glands of internal secretion. (16993223)
1914
50
THREE SHIPS WITH BERIBERI OUTBREAKS SHOWN TO HAVE HAD EXTENSIVE FORMATION OF CARBONIC OXIDES DURING THE VOYAGE -- ANALYSIS OF BERIBERI BLOOD --CONCLUSION THAT BERIBERI IS NOTHING BUT CARBONIC POISONING OF THE BLOOD. (17749988)
1893

Genetic Variations for Beriberi

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Expression for genes affiliated with Beriberi

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Beriberi

Search GEO for disease gene expression data for Beriberi.

Pathways for genes affiliated with Beriberi

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Compounds for genes affiliated with Beriberi

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Sources:
44Novoseek, 24HMDB, 2BitterDB, 11DrugBank, 28IUPHAR
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Compounds related to Beriberi according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1thymine44 2410.3TKT, DPYS
2pyrimidine44 2410.3TKT, DPYS
3thiamin diphosphate449.2TKT, TPK1
4thiamine monophosphate44 2410.2TKT, TPK1
5alpha-ketoglutarate449.1TKT, TPK1
6cytosine44 2410.1DPYS, TKT
7pyruvate449.0TPK1, TKT
8thiamine pyrophosphate44 249.7TPK1, TKT, HACL1
9thiamine44 2 11 2411.7TPK1, TKT, HACL1
10magnesium44 11 2410.5TPK1, TKT, HACL1
11atp44 289.2TPK1, TKT, FHL1

GO Terms for genes affiliated with Beriberi

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Sources:
16Gene Ontology
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Cellular components related to Beriberi according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:0057778.8TKT, HACL1
2cytosolGO:0058298.1TPK1, TKT, DPYS, FHL1

Biological processes related to Beriberi according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:0442818.1TPK1, TKT, DPYS, HACL1

Molecular functions related to Beriberi according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cofactor bindingGO:0480379.1TKT, HACL1

Products for genes affiliated with Beriberi

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Beriberi

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet