Aliases & Classifications for Berylliosis

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Aliases & Descriptions for Berylliosis:

Name: Berylliosis 10 12 36
 
Beryllium Poisoning 10

Classifications:



External Ids:

Disease Ontology10 DOID:10322
ICD1027 J63.2
SNOMED-CT59 8247009
MeSH36 D001607
UMLS65 C0005138

Summaries for Berylliosis

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Disease Ontology:10 A pneumoconiosis that involves allergic response located in lungs caused by inhalation of beryllium compounds.

MalaCards based summary: Berylliosis, also known as beryllium poisoning, is related to chronic beryllium disease and beryllium disease. An important gene associated with Berylliosis is HLA-DPB1 (Major Histocompatibility Complex, Class II, DP Beta 1), and among its related pathways are Glucocorticoid receptor regulatory network and Th2 Differentiation Pathway. Affiliated tissues include lungs, lung and liver, and related mouse phenotypes are liver/biliary system and respiratory system.

Wikipedia:68 Berylliosis, or chronic beryllium disease (CBD), is a chronic allergic-type lung response and chronic... more...

Related Diseases for Berylliosis

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Diseases related to Berylliosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 198)
idRelated DiseaseScoreTop Affiliating Genes
1chronic beryllium disease11.7
2beryllium disease11.7
3post-infectious myocarditis10.9HLA-DPA1, HLA-DPB1
4lichen planus pemphigoides10.9HLA-DQB1, HLA-DRB1
5tucker syndrome10.9HLA-DQB1, HLA-DRB1
6heavy chain deposition disease10.8HLA-DQB1, HLA-DRB1
7pulmonary coin lesion10.8HLA-DQB1, HLA-DRB1
8congenital cataract-progressive muscular hypotonia-hearing loss-developmental delay syndrome10.8HLA-DRB1, TNF
9red cell phospholipid defect with hemolysis10.7HLA-DQB1, HLA-DRB1, IFNG
10mechanical strabismus10.7CD4, IL2
11bipolar ll disorder10.7HLA-DQB1, HLA-DRB1, POMC
12pulmonary nodular lymphoid hyperplasia10.7HLA-DQB1, HLA-DRB1, IFNG
13angioid streaks10.7HLA-DQB1, HLA-DRB1, IL2
14ureterocele10.7IL2, TNF
15acute gonococcal prostatitis10.7CTSA, TNF
16microsomia hemifacial radial defects10.7HLA-DRB1, TNF
17chromophobe renal cell carcinoma10.7ACE, GSTO1
18idiopathic juxtafoveal retinal telangiectasia10.7HLA-DQB1, HLA-DRB1
19human spumaretrovirus infection10.7HLA-DQB1, HLA-DRB1, IL2
20intrahepatic gall duct cancer10.7HLA-DQB1, HLA-DRB1, IFNG
21autoimmune oophoritis10.6IFNG, TNF
22hypochromic microcytic anemia with iron overload10.6ACE, POMC
23autoimmune polyglandular syndrome type 210.6HLA-DQB1, HLA-DRB1, TNF
24neurotic disorder10.6CD4, IFNG, POMC
25pustulosis of palm and sole10.6ACE, TNF
26lymphocytic choriomeningitis10.6HLA-DQB1, HLA-DRB1, TNF
27moderately severe hemophilia a10.6HLA-DQB1, HLA-DRB1, TNF
28hypercementosis10.6HLA-DRB1, IFNG, TNF
29hemorrhagic proctocolitis10.6HLA-DRB1, IFNG, TNF
30hypopharynx cancer10.6HLA-DRB1, POMC, TNF
31cryptosporidiosis10.6HLA-DRB1, IFNG, TNF
32louping ill10.6CD4, IFNG, IL2
33kernicterus due to isoimmunization10.6HLA-DQB1, HLA-DRB1, TNF
34artemis deficiency10.6CD4, HLA-DQB1, IFNG
35cerebral sarcoidosis10.6ACE, TNF
36spinal polio10.6IFNG, IL2
37rectal disease10.6HLA-DQB1, HLA-DRB1, TNF
38skin epithelioid hemangioma10.6IL2, POMC
39blastomycosis10.5IFNG, POMC, TNF
40argentine hemorrhagic fever10.5IFNG, IL2, TNF
41irf6-related disorders10.5CD4, IFNG, IL2
42ethmoid sinus squamous cell carcinoma10.5CD4, IFNG, TNF
43acute leukemia of ambiguous lineage10.5IFNG, IL2, TNF
44lichtenstein syndrome10.5HLA-DQB1, HLA-DRB1
45tethered spinal cord syndrome10.5IFNG, IL2, TNF
46hodgkin's lymphoma, lymphocytic-histiocytic predominance10.5CD4, IFNG, IL2
47viral meningitis10.5CD4, HLA-DQB1, TNF
48pupil disease10.5HLA-DRB1, IFNG, TNF
49leech infestation10.5IFNG, IL2, TNF
50limited scleroderma10.5HLA-DRB1, IFNG, TNF

Graphical network of the top 20 diseases related to Berylliosis:



Diseases related to berylliosis

Symptoms for Berylliosis

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Drugs & Therapeutics for Berylliosis

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Drugs for Berylliosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
InfliximabapprovedPhase 1, Phase 2349170277-31-3
Synonyms:
Ig gamma-1 chain C region
 
Inflectra
Remicade
Remsima
2MesalaminePhase 1, Phase 215289-57-6
3Peripheral Nervous System AgentsPhase 1, Phase 218510
4AnalgesicsPhase 1, Phase 29358
5Contraceptives, OralPhase 1, Phase 23734
6Analgesics, Non-NarcoticPhase 1, Phase 25184
7Antirheumatic AgentsPhase 1, Phase 28496
8Anti-Inflammatory AgentsPhase 1, Phase 28478
9Anti-Inflammatory Agents, Non-SteroidalPhase 1, Phase 23549
10Gastrointestinal AgentsPhase 1, Phase 26401
11Dermatologic AgentsPhase 1, Phase 24555
12
Acetylcysteineapproved293616-91-112035
Synonyms:
(2R)-2-acetylamino-3-Sulfanylpropanoic acid
(R)-2-acetylamino-3-Mercaptopropanoic acid
(R)-Mercapturic acid
2-Acetylamino-3-mercapto-propionate
2-Acetylamino-3-mercapto-propionic acid
ACC
Acetadote
Acetilcisteina
Acetylcysteine
Acetylcysteinum
Fluimicil Infantil
Fluimucetin
Fluimucil
Flumucetin
 
Fluprowit
L-Acetylcysteine
L-alpha-acetamido-beta-Mercaptopropionic acid
Lysox
Mercapturic acid
Mucolysin
Mucomyst
N-ACETYL-L-cysteine
N-Acety-L-Cysteine
N-Acetyl-3-mercaptoalanine
N-Acetyl-L-(+)-cysteine
N-Acetylcysteine
N-acetylcysteine
NAC
Parvolex
Sodium 2-acetamido-3-mercaptopropionate
13
Heparinapproved, investigational7199005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
14Protective Agents5651
15Respiratory System Agents3931
16Anti-Infective Agents17220
17N-monoacetylcystine293
18Antioxidants2442
19Expectorants337
20Antiviral Agents8071
21calcium heparin719
22Pharmaceutical Solutions7004
23cysteineNutraceutical150

Interventional clinical trials:

idNameStatusNCT IDPhase
1Targeting Oxidative Stress in Chronic Beryllium DiseaseCompletedNCT01088243Phase 1, Phase 2
2Beryllium Infliximab Study: Clinical Interventional TrialTerminatedNCT00111917Phase 1, Phase 2
3Identifying Shared Genetic Susceptibility Regions in Chronic Beryllium Disease and SarcoidosisCompletedNCT00560989
4The Effect of an Oral Antioxidant, N-Acetyl-L-Cysteine, on Inflammatory and Oxidative Stress Markers in Pulmonary SarcoidosisCompletedNCT01587001
5The Role of JAK2 in Alveolar Macrophages (AM's) in Chronic Beryllium Disease (CBD)RecruitingNCT02596347
6Exposure in Epigenetic Regulation of Immune Response in Chronic Beryllium Disease (CBD)RecruitingNCT02604693

Search NIH Clinical Center for Berylliosis


Cochrane evidence based reviews: berylliosis

Genetic Tests for Berylliosis

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Anatomical Context for Berylliosis

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MalaCards organs/tissues related to Berylliosis:

33
Lung, Liver, Bone, Skin, B cells, Ovary, Thyroid

FMA organs/tissues related to Berylliosis:

16
Lungs

Animal Models for Berylliosis or affiliated genes

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MGI Mouse Phenotypes related to Berylliosis:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.8ACE, CTSA, GBA, HLA-DQB1, IFNG, IL2
2MP:00053888.5ALPL, CTSA, CTSK, GBA, HLA-DQB1, IFNG
3MP:00053818.1ALPL, CD4, CTSK, HGS, HLA-DQB1, IFNG
4MP:00053798.1ACE, ALPL, CD4, CTSK, GBA, HLA-DQB1
5MP:00053897.7ACE, ALPL, ALPPL2, CTSA, HGS, HLA-DQB1
6MP:00053977.4ACE, ALPL, CD4, CTSA, CTSK, GBA
7MP:00053767.3ACE, ALPL, CD4, CTSA, CTSK, GBA
8MP:00053847.3ALPL, CD4, CTSA, CTSK, GBA, HGS
9MP:00053857.3ACE, ALPL, CTSA, GBA, HGS, HLA-DQB1
10MP:00053877.1ACE, ALPL, CD4, CTSA, CTSK, GBA
11MP:00053786.3ACE, ALPL, ALPPL2, CD4, CTSA, CTSK

Publications for Berylliosis

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Articles related to Berylliosis:

(show top 50)    (show all 73)
idTitleAuthorsYear
1
Role of high-affinity HLA-DP specific CLIP-derived peptides in beryllium binding to the HLA-DPGlu69 berylliosis-associated molecules and presentation to beryllium-sensitized T cells. (19191908)
2009
2
Activation pathways implicate anti-HLA-DP and anti-LFA-1 antibodies as lead candidates for intervention in chronic berylliosis. (15778396)
2005
3
Identification of HLA-DRPhebeta47 as the susceptibility marker of hypersensitivity to beryllium in individuals lacking the berylliosis-associated supratypic marker HLA-DPGlubeta69. (16098233)
2005
4
Role of the berylliosis-associated HLA-DPGlu69 supratypic variant in determining the response to beryllium in a blood T-cells beryllium-stimulated proliferation test. (16315779)
2005
5
Beryllium binding to HLA-DP molecule carrying the marker of susceptibility to berylliosis glutamate beta 69. (11423174)
2001
6
Pulmonary epithelial cell injury and alveolar-capillary permeability in berylliosis. (9230733)
1997
7
Beryllium induces IL-2 and IFN-gamma in berylliosis. (8977230)
1997
8
Chronic berylliosis of the lung: report of a case. (16892748)
1996
9
Scintigraphy with J001X, a Klebsiella membrane glycolipid, for the early diagnosis of chronic berylliosis: results from an experimental model. (1599873)
1992
10
Berylliosis. (2138073)
1990
11
A study of immunological indices for diagnosis of chronic berylliosis. (2604898)
1989
12
Pulmonary berylliosis on corticosteroid therapy, with cavitating lung lesions and aspergillomata--report on a fatal case. (3328191)
1987
13
Inhalant granulomas: silicosis, asbestosis, berylliosis. (7133715)
1982
14
Bronchoalveolar lavage in a patient with chronic berylliosis: evidence for hypersensitivity pneumonitis. (7103279)
1982
15
Pulmonary berylliosis: report on a fatal case. (7126443)
1982
16
Berylliosis. (7381961)
1980
17
Non-bony uptake of technetium-99m MDP in berylliosis. (7437734)
1980
18
Mixed pneumoconiosis: silicosis, asbestosis, talcosis, and berylliosis. (436529)
1979
19
Case report. Pulmonary berylliosis following exposure to beryllium-copper. (1063889)
1976
20
Research into what happens in berylliosis. (1048889)
1976
21
The influence of cutaneous hypersensitivity to beryllium on the development of experimental pulmonary berylliosis. (4533844)
1974
22
Chronic berylliosis. (4274186)
1973
23
Immunologic aspects of chronic berylliosis. (4540228)
1973
24
A study of the immunologic aspects of chronic berylliosis. (4690875)
1973
25
Immunity to pulmonary berylliosis in guinea pigs. (5036157)
1972
26
Immunoglobulin concentrationsn berylliosis. (4191591)
1970
27
Immunoglobulin levels in berylliosis. (4129664)
1970
28
Pulmonary berylliosis: a case report. (6083249)
1967
29
Chronic berylliosis and calcospherite deposition. (5901642)
1966
30
Berylliosis: report of two cases, with special reference to the patch test. (13938965)
1963
31
Chronic berylliosis. (14498247)
1962
32
Chronic pulmonary berylliosis in a female chemist. (13773748)
1961
33
The intravenous use of ethylenediamine tetraacetic acid in the treatment of pulmonary berylliosis. A case report. (13768361)
1960
34
Berylliosis, bones, and behavior: an illustrative case report. (13738917)
1960
35
Beryllium and berylliosis. (13580272)
1958
36
Berylliosis. (14371570)
1955
37
An unusual case of joint pains and fever; berylliosis and pulmonary hypertension mistaken for rheumatic fever. (13172869)
1954
38
Berylliosis; summary and survey of all clinical types observed in a twelve-year period. (13057385)
1953
39
Berylliosis; acute pneumonitis and pulmonary granulomatosis of beryllium workers. (14940683)
1952
40
Chronic berylliosis in the neon sign industry. (14837525)
1951
41
Berylliosis and silicosis. (14841360)
1951
42
Some aspects of berylliosis. (14819024)
1951
43
Chronic pulmonary berylliosis in workers using fluorescent powders containing beryllium. (15426337)
1950
44
Berylliosis; brief discussion and presentation of a case with pulmonary, digital and axillary node involvement. (14780026)
1950
45
Berylliosis. (14771889)
1950
46
Non-occupational berylliosis. (18141686)
1949
47
The value of beryllium determinations in the diagnosis of berylliosis. (18114454)
1949
48
Berylliosis; acute pneumonitis and pulmonary granulomatosis of beryllium workers. (18113769)
1948
49
Berylliosis; observations and report of clinical study of 70 cases of chronic disease. (18208267)
1948
50
Berylliosis. (18102274)
1948

Variations for Berylliosis

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Expression for genes affiliated with Berylliosis

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Search GEO for disease gene expression data for Berylliosis.

Pathways for genes affiliated with Berylliosis

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Pathways related to Berylliosis according to GeneCards Suite gene sharing:

(show all 36)
idSuper pathwaysScoreTop Affiliating Genes
19.8IFNG, IL2, POMC
29.7CD4, IFNG, IL2
39.7IFNG, IL2, TNF
4
Show member pathways
9.7IFNG, IL2, TNF
5
Show member pathways
9.7IFNG, IL2, TNF
6
Show member pathways
9.7IFNG, IL2, TNF
79.7CD4, HLA-DRB1, TNF
8
Show member pathways
9.5CD4, HLA-DRB1, IFNG, IL2
99.5CD4, HLA-DRB1, IFNG, IL2
109.4HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
11
Show member pathways
9.4CD4, IFNG, IL2, TNF
129.4CD4, IFNG, IL2, TNF
139.4CD4, IFNG, IL2, TNF
149.4CD4, IFNG, IL2, TNF
159.4CD4, HGS, HLA-DRB1
169.3CD4, HLA-DPA1, HLA-DQB1, HLA-DRB1
179.2CD4, HLA-DRB1, IFNG, IL2, TNF
18
Show member pathways
9.2HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG
199.2HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG
209.2ALPL, ALPP, ALPPL2
21
Show member pathways
9.2ALPL, ALPP, ALPPL2
229.1CD4, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
23
Show member pathways
9.1CD4, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
24
Show member pathways
9.1CD4, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
25
Show member pathways
9.1CD4, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
26
Show member pathways
9.1CD4, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
27
Show member pathways
9.1CD4, HLA-DPA1, HLA-DQB1, HLA-DRB1, IL2
28
Show member pathways
8.9CD4, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IL2
298.9HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG, TNF
30
Show member pathways
8.9HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG, TNF
318.9HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IL2, TNF
328.9CTSA, CTSK, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
338.8HGS, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
34
Show member pathways
8.6HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG, IL2
358.6CTSK, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG
36
Show member pathways
8.4CD4, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG

GO Terms for genes affiliated with Berylliosis

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Cellular components related to Berylliosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:004261310.1HLA-DPA1, HLA-DPB1, HLA-DQB1
2integral component of lumenal side of endoplasmic reticulum membraneGO:007155610.0HLA-DPA1, HLA-DPB1, HLA-DQB1
3endosome membraneGO:00100089.6HLA-DPA1, HLA-DPB1, HLA-DQB1
4ER to Golgi transport vesicle membraneGO:00125079.4HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1
5trans-Golgi network membraneGO:00325889.3HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1

Biological processes related to Berylliosis according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.7HLA-DQB1, HLA-DRB1
2positive regulation of calcidiol 1-monooxygenase activityGO:006055910.5IFNG, TNF
3positive regulation of membrane protein ectodomain proteolysisGO:005104410.5IFNG, TNF
4positive regulation of chemokine biosynthetic processGO:004508010.5IFNG, TNF
5negative regulation of growth of symbiont in hostGO:004413010.4IFNG, TNF
6positive regulation of isotype switching to IgG isotypesGO:004830410.4IFNG, IL2
7protein import into nucleus, translocationGO:000006010.3IFNG, TNF
8antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIGO:000250410.3HLA-DPA1, HLA-DPB1, HLA-DRB1
9positive regulation of osteoclast differentiationGO:004567210.2IFNG, TNF
10response to glucocorticoidGO:00513849.8ALPL, GBA, TNF
11cytokine-mediated signaling pathwayGO:00192219.7HLA-DPA1, HLA-DPB1, HLA-DRB1, IFNG
12positive regulation of exosomal secretionGO:19035439.6HGS, IFNG
13positive regulation of T cell activationGO:00508709.6CD4, HLA-DPA1, HLA-DPB1
14antigen processing and presentationGO:00198829.6HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG
15immune responseGO:00069559.2CD4, HLA-DRB1, IFNG, IL2, TNF

Sources for Berylliosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet