MCID: BLR006
MIFTS: 53

Biliary Tract Disease

Categories: Gastrointestinal diseases

Aliases & Classifications for Biliary Tract Disease

MalaCards integrated aliases for Biliary Tract Disease:

Name: Biliary Tract Disease 12 14
Biliary Tract Diseases 42 69
Biliary Tract Abnormality 29

Classifications:



External Ids:

Disease Ontology 12 DOID:9741
ICD10 33 K83.9 K83.8
ICD9CM 35 576.9
MeSH 42 D001660
UMLS 69 C0005424

Summaries for Biliary Tract Disease

MalaCards based summary : Biliary Tract Disease, also known as biliary tract diseases, is related to alport syndrome and thin basement membrane nephropathy and cholestasis, intrahepatic, of pregnancy, 3, and has symptoms including digestive system symptom An important gene associated with Biliary Tract Disease is NR1H4 (Nuclear Receptor Subfamily 1 Group H Member 4), and among its related pathways/superpathways are Metabolism and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. The drugs Ketamine and Remifentanil have been mentioned in the context of this disorder. Affiliated tissues include liver, lung and pancreas, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism

Related Diseases for Biliary Tract Disease

Diseases related to Biliary Tract Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
id Related Disease Score Top Affiliating Genes
1 alport syndrome and thin basement membrane nephropathy 10.7 ABCB11 ATP8B1 NR1H4
2 cholestasis, intrahepatic, of pregnancy, 3 10.6 ABCB11 ABCB4 ATP8B1
3 malignant fibrous histiocytoma of bone 10.6 CYP7A1 NR1H4 NR1I2
4 aneurysm, intracranial berry, 9 10.6 CYP7A1 NR1H4 NR1I2
5 cholestasis, intrahepatic, of pregnancy, 1 10.6 ABCB11 ATP8B1
6 bardet-biedl syndrome 6 10.5 ABCB11 ABCB4 ATP8B1
7 cholestasis, benign recurrent intrahepatic, 2 10.5 ABCB11 ABCB4 ATP8B1 NR1H4
8 alzheimer disease 6 10.5 ABCC2 ABCC3 ABCC4
9 tolosa-hunt syndrome 10.5 GGT1 GGT2
10 acute cholangitis 10.4 ABCB11 ABCB4 ALB NR1I2
11 patent foramen ovale 10.4 ABCB11 ALB NR1H4 SLC10A1
12 autoimmune disease of cardiovascular system 10.4 ABCB4 ALB GGT2
13 fallopian tube leiomyosarcoma 10.4 ABCB4 ALB CCK
14 malignant visceral pleura tumor 10.4 GGT1 GGT2
15 intussusception 10.4 ALB CCK
16 limb ischemia 10.3 GGT1 GGT2
17 intraorbital meningioma 10.3 CCK GGT2
18 microcephaly, progressive, seizures, and cerebral and cerebellar atrophy 10.3 ABCB4 GGT1 NR1I2
19 anhidrosis 10.3 ABCB4 CCK
20 pancreatic cystadenocarcinoma 10.3 ALB GGT1 GGT2
21 paranasal sinus sarcoma 10.3 ALB GGT1 SLC25A13
22 prostate cancer, progression and metastasis of 10.2 ABCB4 ALB GGT1 NR1H4
23 isthmus cancer 10.2 ABCB11 ABCB4 ALB GGT1
24 pyelitis 10.2 ABCC2 ALB GGT1 NR1I3
25 chorioangioma 10.2 GGT1 GGT2
26 cholestasis, benign recurrent intrahepatic 10.2 ABCB11 ABCB4 ATP8B1 GGT1 NR1H4
27 dermatomyositis 10.1 ABCB4 ALB CCK CYP7A1 NR1H4
28 pancreatitis 10.1
29 cholecystitis 9.9
30 stenosis of lacrimal punctum 9.9 GGT1 GGT2
31 hepatitis 9.8
32 obstructive jaundice 9.8
33 duodenitis 9.8
34 sickle cell anemia 9.8
35 cholelithiasis 9.8
36 sclerosing cholangitis 9.8
37 cholangitis 9.8
38 tuberculum sellae meningioma 9.7 ABCB11 ALB CCK GGT1 GGT2 NR1I2
39 lymphoblastic lymphoma 9.7 ABCB11 ABCB4 ALB ATP8B1 GGT1 NR1H4
40 campylobacteriosis 9.6 ABCB4 ABCC2 ABCC3 CYP7A1 GGT1 SLCO1A2
41 duodenal atresia 9.6
42 obesity 9.6
43 cystic fibrosis 9.6
44 down syndrome 9.6
45 thalassemia 9.6
46 portal hypertension 9.6
47 chlamydia 9.6
48 bacteriuria 9.6
49 gastroenteritis 9.6
50 cystadenoma 9.6

Comorbidity relations with Biliary Tract Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Pancreatitis

Graphical network of the top 20 diseases related to Biliary Tract Disease:



Diseases related to Biliary Tract Disease

Symptoms & Phenotypes for Biliary Tract Disease

UMLS symptoms related to Biliary Tract Disease:


digestive system symptom

GenomeRNAi Phenotypes related to Biliary Tract Disease according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.66 ABCC3
2 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.66 GGT2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.66 ABCC3 GGT1 GGT2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-131 9.66 GGT2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.66 ABCB11 ABCC3 GGT1 GGT2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.66 ABCC3
7 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.66 GGT1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-174 9.66 ABCC3
9 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.66 ABCC3
10 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.66 ABCC3
11 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.66 ABCB11
12 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.66 GGT2
13 Increased shRNA abundance (Z-score > 2) GR00366-A-54 9.66 ABCB11
14 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.66 GGT1 GGT2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-88 9.66 ABCB11
16 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.66 ABCB11

MGI Mouse Phenotypes related to Biliary Tract Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.86 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4 ALB
2 liver/biliary system MP:0005370 9.44 ABCC2 ABCC3 ALB ATP8B1 CYP7A1 CYP8B1

Drugs & Therapeutics for Biliary Tract Disease

Drugs for Biliary Tract Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 504)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
2
Remifentanil Approved Phase 4 132875-61-7 60815
3
Benzocaine Approved Phase 4,Phase 2 1994-09-7, 94-09-7 2337
4
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2 2078-54-8 4943
5
Dopamine Approved Phase 4,Phase 3 51-61-6, 62-31-7 681
6
Droperidol Approved, Vet_approved Phase 4 548-73-2 3168
7
Gabapentin Approved, Investigational Phase 4,Phase 3 60142-96-3 3446
8
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
9
Flurbiprofen Approved, Investigational Phase 4 5104-49-4 3394
10
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
11
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
12
Etomidate Approved Phase 4 33125-97-2 36339 667484
13
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
14
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
15
Ursodeoxycholic acid Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128-13-2 31401
16
Pancrelipase Approved Phase 4,Phase 2,Phase 1 53608-75-6
17
Acetaminophen Approved Phase 4 103-90-2 1983
18
Alfentanil Approved, Illicit Phase 4 71195-58-9 51263
19
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
20
Meperidine Approved Phase 4 57-42-1 4058
21
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
22
Ibuprofen Approved Phase 4 15687-27-1 3672
23
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
24
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 5281106 54677470
25
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
26
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
27
Ephedrine Approved Phase 4 299-42-3 9294
28
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
29
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
30
Morphine Approved, Investigational Phase 4,Phase 2 57-27-2 5288826
31
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
32
Ondansetron Approved Phase 4 99614-02-5 4595
33
Pseudoephedrine Approved Phase 4 90-82-4 7028
34
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1 443-48-1 4173
35
Levobupivacaine Approved Phase 4 27262-47-1 92253
36
Secretin Approved, Investigational Phase 4 108153-74-8
37
Ceftriaxone Approved Phase 4,Phase 2 73384-59-5 5479530 5361919
38
Minocycline Approved, Investigational Phase 4,Phase 1 10118-90-8 5281021
39
Tigecycline Approved Phase 4,Phase 1 220620-09-7 5282044
40
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
41
Vancomycin Approved Phase 4,Phase 3,Phase 1 1404-90-6 441141 14969
42
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
43
Tauroursodeoxycholic acid Approved, Investigational Phase 4,Phase 3 14605-22-2 12443252
44
chenodeoxycholic acid Approved Phase 4,Phase 3,Phase 2,Early Phase 1 474-25-9 10133
45
Desflurane Approved Phase 4 57041-67-5 42113
46
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
47
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
48
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
49
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
50
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096

Interventional clinical trials:

(show top 50) (show all 936)

id Name Status NCT ID Phase Drugs
1 SILS™ Port Laparoscopic Cholecystectomy Post Market Study Unknown status NCT00832767 Phase 4
2 Efficacy and Safety of Floseal for the Haemostasis During Laparoscopic Cholecystectomy in Acute Cholecystitis (GLA) Unknown status NCT01126281 Phase 4
3 Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia Unknown status NCT02493231 Phase 4 Nefopam;Ketamine;Saline
4 Closed-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy Unknown status NCT02114437 Phase 4
5 Laparo-endoscopic Single Site (LESS) Cholecystectomy Versus Standard LAP-CHOLE Unknown status NCT01339325 Phase 4
6 Day-care Versus Overnight-stay Laparoscopic Cholecystectomy Randomized Controlled Trial. Unknown status NCT01052727 Phase 4
7 Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy Unknown status NCT00209885 Phase 4 Gabapentin;S-ketamine;Lidocaine;Droperidol
8 Winged Perimeter Versus Traditional Plastic Biliary Stent for Malignant Bile Duct Obstruction Unknown status NCT01514214 Phase 4
9 Uncovered Self-expandable Metal Stent Versus Double Layer Plastic Stent for Malignant Hilar Stricture Unknown status NCT01125865 Phase 4
10 Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial Unknown status NCT02300480 Phase 4
11 Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies Unknown status NCT00792389 Phase 4
12 Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy Unknown status NCT01256047 Phase 4
13 Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children Unknown status NCT02013986 Phase 4 etomidate;midazolam;propofol
14 Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy Unknown status NCT01969110 Phase 4
15 Efficacy and Safety of S-adenosyl-l-methionine in Treatment of Alcoholic Hepatitis With Cholestasis Unknown status NCT02024295 Phase 4 Ademethionine;Polyene Phosphatidyl choline;Ademethionine
16 Efficacy and Safety of S-adenosyl-L-methionine in Treatment of Chronic Hepatitis B Patients With Cholestasis Unknown status NCT01998620 Phase 4 Ademetionine 2;Ademetionine 1;Ademetionine 3
17 Spy II Clinical Registry Completed NCT00751998 Phase 4
18 Alfentanil Versus Remifentanil in Patient-controlled Sedation During Endoscopic Retrograde Cholangiopancreatography (ERCP) Completed NCT01350037 Phase 4 alfentanil;remifentanil
19 Cocktail Sedation Containing Propofol Versus Conventional Sedation for Endoscopic Retrograde Cholangiopancreatography (ERCP) Completed NCT01540084 Phase 4 propofol
20 Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. Completed NCT01709422 Phase 4 Propofol;Midazolam;Meperidine
21 The Usefulness of Endoscopic Ultrasound-guided Biliary Drainage With a Newly Designed Hybrid Metallic Stent Completed NCT01862198 Phase 4
22 A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982) Completed NCT01728584 Phase 4 Rocuronium;Sugammadex
23 Effect IV Ibuprofen and Inflammatory Responses Completed NCT01938040 Phase 4 ibuprofen
24 Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy Completed NCT01833819 Phase 4 Dexmedetomidine and lidocaine;Remifentanil
25 Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction Completed NCT02909595 Phase 4
26 Vitamin C Efficacy in Reducing Post Operative Pain Completed NCT01322061 Phase 4 Ascorbic Acid
27 Cholecyst- Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy Completed NCT01103570 Phase 4
28 Radiofrequency Ablation for Malignant Biliary Obstruction Completed NCT01758341 Phase 4
29 Clinical Study About the Role of COX-2 Inhibitor in Liver Cirrhosis With Biliary Atresia Completed NCT02298218 Phase 4 Meloxicam
30 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4 ursodeoxycholic acid
31 Minilaparoscopic Versus Conventional Laparoscopic Cholecystectomy Completed NCT01397565 Phase 4
32 Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy Completed NCT02327923 Phase 4 Lidocaine;Esmolol;Paracetamol;Lidocaine;Propofol;Fentanyl;Vecuronium;Atropine;Ephedrine;Morphine;Ketorolac;Ondansetron;Bupivacaine;Tramadol;Neostigmine;Glycopyrrolate
33 Effect of Rowachol on Prevention of Postcholecystectomy Syndrome Completed NCT01765465 Phase 4 Rowachol;Placebo
34 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
35 Endovenous Lidocaine and Serum Cytokines Concentration Completed NCT02363699 Phase 4 Lidocaine;Saline solution
36 Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI) Completed NCT02116985 Phase 4
37 Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy Completed NCT01211743 Phase 4
38 Multi-Port Versus Single-port Cholecystectomy Completed NCT01104727 Phase 4
39 Levobupivacaine During Cholecystectomy Completed NCT00836316 Phase 4 levobupivacaine
40 Robotic Assisted Versus Laparoscopic Cholecystectomy - Outcome and Cost Analyses of a Case-Matched Control Study Completed NCT00562900 Phase 4
41 A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers Completed NCT01134848 Phase 4 Morphine;Neostigmine;0.9% saline;Secretin;0.9% saline
42 Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis Completed NCT02557360 Phase 4
43 Covered vs. Uncovered SEMS for Occluded Biliary Metal Stents Completed NCT01315522 Phase 4
44 Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction Completed NCT00280709 Phase 4
45 Ursofalk Tablets (500 mg) Versus Ursofalk Capsules (250 mg) in the Treatment of Primary Biliary Cirrhosis Completed NCT01510860 Phase 4 UDCA (Ursodeoxycholic acid);UDCA (Ursodeoxycholic acid)
46 Comparing Covered Self-expandable Metallic Stent (SEMS) Above/Across the Sphincter of Oddi Completed NCT01041612 Phase 4
47 RCT Steel (Wallstent®) vs Nitinol (Wallflex®) Bile Duct Stent for Palliation of Malignant Obstruction Completed NCT00980889 Phase 4
48 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
49 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
50 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole

Search NIH Clinical Center for Biliary Tract Disease

Cochrane evidence based reviews: biliary tract diseases

Genetic Tests for Biliary Tract Disease

Genetic tests related to Biliary Tract Disease:

id Genetic test Affiliating Genes
1 Biliary Tract Abnormality 29

Anatomical Context for Biliary Tract Disease

MalaCards organs/tissues related to Biliary Tract Disease:

39
Liver, Lung, Pancreas, Testes, T Cells, Breast, Bone

Publications for Biliary Tract Disease

Articles related to Biliary Tract Disease:

(show top 50) (show all 280)
id Title Authors Year
1
Risk and Surveillance of Cancers in Primary Biliary Tract Disease. ( 27413366 )
2016
2
Association of Statin Therapy and Risks of Cholelithiasis, Biliary Tract Diseases, and Gallbladder Procedures: Retrospective Cohort Analysis of a US Population. ( 26706861 )
2016
3
Single-incision laparoscopic surgery for biliary tract disease. ( 26811621 )
2016
4
Primary Sclerosing Cholangitis as a Premalignant Biliary Tract Disease: Surveillance and Management. ( 26051390 )
2015
5
Body mass index and biliary tract disease: a systematic review and meta-analysis of prospective studies. ( 24721739 )
2014
6
Impact of an acute care surgery model with a dedicated daytime operating room on outcomes and timeliness of care in patients with biliary tract disease. ( 23756774 )
2013
7
Ketamine abuse, biliary tract disease, and secondary sclerosing cholangitis. ( 23695896 )
2013
8
Endoscopic diagnosis of biliary tract disease. ( 22343346 )
2012
9
Prognostic relevance of circulating CK19 mRNA in advanced malignant biliary tract diseases. ( 22253524 )
2012
10
Role of intraoperative flexible Choledochoscopy in calculous biliary tract disease. ( 22828544 )
2012
11
Cholangioscopy using a new type of cholangioscope for the diagnosis of biliary tract disease: a case series. ( 22814962 )
2012
12
Transgastric endoscopic retrograde cholangiopancreatography for the management of biliary tract disease after Roux-en-Y gastric bypass treatment for obesity. ( 22460551 )
2012
13
Peroral cholangioscopy for diagnosis and therapy of biliary tract disease using an ultra-slim gastroscope. ( 21823068 )
2011
14
Imaging of biliary tract disease. ( 21940525 )
2011
15
A stunning year for advances in biliary tract disease. ( 21423005 )
2011
16
Vascular factors, angiogenesis and biliary tract disease. ( 20061944 )
2010
17
Endoscopic retrograde cholangiopancreatography in pancreatic and biliary tract disease in Korean children. ( 20101777 )
2010
18
Management of biliary tract disease during pregnancy. ( 20193902 )
2010
19
Farnesoid X receptor agonists in biliary tract disease. ( 19300246 )
2009
20
Minimally invasive management of acute biliary tract disease during pregnancy. ( 19606252 )
2009
21
The role of international classification of diseases in assessment of patients with biliary tract disease. ( 19745312 )
2009
22
Double-balloon enteroscopy application in biliary tract disease-its therapeutic and diagnostic functions. ( 18561917 )
2008
23
Management of biliary tract disease during pregnancy: a decision analysis. ( 17713817 )
2008
24
Chlamydia infection as risk factor for pediatric biliary tract disease. ( 18334886 )
2008
25
Liver transplantation in precirrhotic biliary tract disease: Portal hypertension is frequently associated with nodular regenerative hyperplasia and obliterative portal venopathy. ( 17063088 )
2006
26
Biliary tract disease as a risk factor for Plesiomonas shigelloides bacteraemia: a nine-year experience in a Hong Kong hospital and review of the literature. ( 15782626 )
2005
27
Bacteriuria in patients with gallbladder and biliary tract diseases. ( 16295397 )
2004
28
Medical versus surgical management of biliary tract disease in pregnancy. ( 15619495 )
2004
29
Lymphoplasmacytic chronic cholecystitis and biliary tract disease in patients with lymphoplasmacytic sclerosing pancreatitis. ( 12657928 )
2003
30
Diffuse lymphoplasmacytic chronic cholecystitis is highly specific for extrahepatic biliary tract disease but does not distinguish between primary and secondary sclerosing cholangiopathy. ( 14508392 )
2003
31
Prenatal diagnosis of liver and biliary tract disease. ( 15001123 )
2003
32
Gallbladder and biliary tract disease in the intensive care unit. ( 12610852 )
2003
33
Helicobacter pylori and the risk of benign and malignant biliary tract disease. ( 12879485 )
2003
34
Biliary tract disease: a rare manifestation of eosinophilic gastroenteritis. ( 12757181 )
2003
35
Bacteriology and antimicrobial susceptibility in biliary tract disease: an audit of 10-year's experience. ( 12197428 )
2002
36
Imaging the spectrum of biliary tract disease. ( 12479714 )
2002
37
The role of microorganisms in biliary tract disease. ( 11900683 )
2002
38
Helicobacter pylori and the risk of benign and malignant biliary tract disease. ( 12404289 )
2002
39
MR and ultrasound in screening of patients with suspected biliary tract disease. ( 11972468 )
2002
40
Endoscopic management of biliary tract disease. ( 17031203 )
2001
41
Trypsinogen-1, -2 and tumour-associated trypsin-inhibitor in bile and biliary tract tissues from patients with biliary tract diseases and pancreatic carcinomas. ( 11347977 )
2001
42
Biliary tract disease and acute non-A-E hepatitis in Hong Kong: prospective study. ( 11514745 )
2001
43
Endoscopic therapy for biliary tract disease before orthotopic liver transplantation. ( 11175974 )
2001
44
Role of operative flexible choledochoscopy in calculous biliary tract disease. ( 10881633 )
2000
45
Management of biliary tract disease in heart and lung transplant patients. ( 11015098 )
2000
46
[The pathogenesis of biliary stone formation and its prevention in biliary tract diseases]. ( 10222553 )
1999
47
Experience with percutaneous transhepatic cholangioscopy (PTCS) in the management of biliary tract disease. ( 10594265 )
1999
48
Recommendations for management of liver and biliary tract disease in cystic fibrosis. Cystic Fibrosis Foundation Hepatobiliary Disease Consensus Group. ( 9934970 )
1999
49
The use of magnetic resonance cholangiopancreatography in the management of biliary tract disease in pregnancy. ( 15512428 )
1999
50
Endoscopic and surgical integration in the approach to biliary tract disease. ( 10192603 )
1999

Variations for Biliary Tract Disease

Expression for Biliary Tract Disease

Search GEO for disease gene expression data for Biliary Tract Disease.

Pathways for Biliary Tract Disease

Pathways related to Biliary Tract Disease according to GeneCards Suite gene sharing:

(show all 22)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.99 ABCB11 ABCB4 ABCC3 ALB CYP7A1 CYP8B1
2
Show member pathways
13.27 ABCB4 ABCC2 ABCC3 ABCC4 ALB ATP8B1
3 12.37 ABCC2 ABCC3 ABCC4 NR1H2
4
Show member pathways
12.17 ABCB11 ABCC3 ALB CYP7A1 CYP8B1 NR1H4
5 11.99 ABCC2 ABCC3 ABCC4 GGT1 GGT2
6
Show member pathways
11.9 ABCB11 ABCB4 ABCC2 SLC10A1 SLCO1A2
7
Show member pathways
11.75 NR1H2 NR1H4 NR1I2 NR1I3
8
Show member pathways
11.71 ABCB11 ABCC2 ABCC4 SLCO1A2
9 11.71 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4 CYP7A1
10
Show member pathways
11.65 ABCC2 ABCC3 ABCC4
11
Show member pathways
11.48 ABCC2 NR1I2 NR1I3
12 11.22 ABCC2 ABCC3 NR1I3
13 11.19 ABCC2 ABCC3 ABCC4
14 11.07 ABCC2 ABCC3 ABCC4
15 11.01 ABCB11 ABCB4 CYP7A1 CYP8B1 NR1H4 SLC10A1
16
Show member pathways
10.97 ABCC2 ABCC3 ABCC4 SLCO1A2
17 10.89 ABCC2 ABCC3 ABCC4
18 10.89 ABCB11 ABCC2 ABCC3 ABCC4 CYP7A1 NR1H4
19 10.82 ABCB11 ABCB4 ABCC2 ABCC3 CYP7A1 CYP8B1
20 10.77 ABCC3 NR1I2
21 10.7 ABCC2 NR1I2
22 10.57 ABCC2 ABCC3

GO Terms for Biliary Tract Disease

Cellular components related to Biliary Tract Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.56 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4 ATP8B1
2 brush border membrane GO:0031526 9.33 ABCB4 ABCC2 ATP8B1
3 intercellular canaliculus GO:0046581 8.8 ABCB11 ABCB4 ABCC2

Biological processes related to Biliary Tract Disease according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 transmembrane transport GO:0055085 9.98 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4 SLC10A1
2 transcription initiation from RNA polymerase II promoter GO:0006367 9.85 NR1H2 NR1H4 NR1I2 NR1I3
3 steroid hormone mediated signaling pathway GO:0043401 9.71 NR1H2 NR1H4 NR1I2 NR1I3
4 intracellular receptor signaling pathway GO:0030522 9.69 NR1H4 NR1I2 NR1I3
5 bile acid biosynthetic process GO:0006699 9.63 ABCB11 CYP7A1 CYP8B1
6 bile acid metabolic process GO:0008206 9.58 ATP8B1 NR1H4
7 zymogen activation GO:0031638 9.58 GGT1 GGT2
8 glutathione catabolic process GO:0006751 9.57 GGT1 GGT2
9 regulation of cholesterol homeostasis GO:2000188 9.56 NR1H2 NR1H4
10 drug export GO:0046618 9.54 ABCB4 NR1I2
11 response to antineoplastic agent GO:0097327 9.52 ABCB4 ABCC2
12 xenobiotic transport GO:0042908 9.5 ABCB4 ABCC3 NR1I2
13 positive regulation of cholesterol transport GO:0032376 9.49 ABCB4 NR1H2
14 regulation of bile acid biosynthetic process GO:0070857 9.48 CYP7A1 NR1H4
15 drug transmembrane transport GO:0006855 9.46 ABCB4 ABCC2 ABCC3 ATP8B1
16 canalicular bile acid transport GO:0015722 9.26 ABCB11 ABCC2
17 ATP hydrolysis coupled anion transmembrane transport GO:0099133 9.26 ABCB11 ABCC2 ABCC3 ABCC4
18 bile acid and bile salt transport GO:0015721 9.23 ABCB11 ABCC3 ALB ATP8B1 NR1H4 SLC10A1
19 transport GO:0006810 10.11 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4 ALB

Molecular functions related to Biliary Tract Disease according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 ATPase activity GO:0016887 9.8 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4
2 transporter activity GO:0005215 9.77 ABCB11 ABCC2 ABCC3 SLC25A13 SLC51B
3 steroid hormone receptor activity GO:0003707 9.62 NR1H2 NR1H4 NR1I2 NR1I3
4 organic anion transmembrane transporter activity GO:0008514 9.61 ABCC2 ABCC3 SLCO1A2
5 retinoid X receptor binding GO:0046965 9.52 NR1H2 NR1H4
6 bile acid transmembrane transporter activity GO:0015125 9.51 SLC10A1 SLCO1A2
7 glutathione hydrolase activity GO:0036374 9.49 GGT1 GGT2
8 xenobiotic-transporting ATPase activity GO:0008559 9.48 ABCB4 ABCC3
9 bile acid-exporting ATPase activity GO:0015432 9.46 ABCB11 ABCC3
10 ATPase-coupled anion transmembrane transporter activity GO:0043225 9.43 ABCC2 ABCC3 ABCC4
11 thyroid hormone receptor activity GO:0004887 9.33 NR1H4 NR1I2 NR1I3
12 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879 9.26 NR1H2 NR1H4 NR1I2 NR1I3
13 ATPase activity, coupled to transmembrane movement of substances GO:0042626 9.02 ABCB11 ABCB4 ABCC2 ABCC3 ABCC4

Sources for Biliary Tract Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....