MCID: BPH002
MIFTS: 29

Biphasic Synovial Sarcoma

Categories: Cancer diseases

Aliases & Classifications for Biphasic Synovial Sarcoma

MalaCards integrated aliases for Biphasic Synovial Sarcoma:

Name: Biphasic Synovial Sarcoma 12 14
Synovial Sarcoma, Biphasic 12 69
Biphasic Sarcoma of Synovium 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5492
NCIt 46 C4279
SNOMED-CT 64 18588008
UMLS 69 C0334507

Summaries for Biphasic Synovial Sarcoma

MalaCards based summary : Biphasic Synovial Sarcoma, also known as synovial sarcoma, biphasic, is related to sarcoma, synovial and ewing sarcoma. An important gene associated with Biphasic Synovial Sarcoma is CDH1 (Cadherin 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Striated Muscle Contraction. Affiliated tissues include testis and small intestine.

Related Diseases for Biphasic Synovial Sarcoma

Diseases related to Biphasic Synovial Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 sarcoma, synovial 29.0 CDH1 DES HEATR3 MUC1 SSX1 VIM
2 ewing sarcoma 28.7 DES EWSR1 VIM
3 sarcoma 10.8
4 lobular neoplasia 10.4 CDH1 MUC1
5 lymphoepithelioma-like carcinoma 10.3 CDH1 MUC1
6 signet ring cell adenocarcinoma 10.3 CDH1 MUC1
7 tubular adenocarcinoma 10.3 CDH1 MUC1
8 spindle cell thymoma 10.3 DES MUC1
9 spindle cell rhabdomyosarcoma 10.3 DES MUC1
10 myxofibrosarcoma 10.3 DES MUC1
11 bile duct adenocarcinoma 10.3 CDH1 MUC1
12 ischemic fasciitis 10.3 DES MUC1
13 adenoid squamous cell carcinoma 10.3 CDH1 VIM
14 plasmablastic lymphoma 10.3 DES MUC1
15 proximal spinal muscular atrophy 10.3 DES MUC1
16 esophagus squamous cell carcinoma 10.3 CDH1 VIM
17 malignant ovarian surface epithelial-stromal neoplasm 10.3 CDH1 MUC1
18 malignant peritoneal mesothelioma 10.3 MUC1 VIM
19 papillary tumor of the pineal region 10.3 MUC1 VIM
20 ovary epithelial cancer 10.3 CDH1 MUC1
21 fibrous meningioma 10.3 MUC1 VIM
22 chordoid meningioma 10.3 MUC1 VIM
23 malignant mixed mullerian tumor 10.3 MUC1 VIM
24 nodular hidradenoma 10.3 MUC1 VIM
25 clear cell meningioma 10.3 MUC1 VIM
26 eccrine porocarcinoma 10.3 MUC1 VIM
27 endometrial mucinous adenocarcinoma 10.3 MUC1 VIM
28 adenofibroma 10.3 MUC1 VIM
29 myxopapillary ependymoma 10.3 MUC1 VIM
30 sarcomatoid mesothelioma 10.3 MUC1 VIM
31 cholecystitis 10.3 CDH1 MUC1
32 myxoid chondrosarcoma 10.3 EWSR1 MUC1
33 anaplastic ependymoma 10.3 MUC1 VIM
34 hidradenoma 10.2 MUC1 VIM
35 skin glomus tumor 10.2 DES VIM
36 infantile digital fibromatosis 10.2 DES VIM
37 sertoli cell tumor 10.2 MUC1 VIM
38 lymphangiomatosis 10.2 DES VIM
39 angiolipoma 10.2 DES VIM
40 mucinous cystadenocarcinoma 10.2 MUC1 VIM
41 primitive neuroectodermal tumor of the cervix uteri 10.2 DES VIM
42 cutaneous leiomyosarcoma 10.2 DES VIM
43 perineurioma 10.2 MUC1 VIM
44 spiradenoma 10.2 MUC1 VIM
45 spindle cell lipoma 10.2 DES VIM
46 epulis 10.2 DES VIM
47 epithelioid leiomyosarcoma 10.2 DES VIM
48 dermoid cyst 10.2 MUC1 VIM
49 dendritic cell tumor 10.2 MUC1 VIM
50 benign metastasizing leiomyoma 10.2 DES VIM

Graphical network of the top 20 diseases related to Biphasic Synovial Sarcoma:



Diseases related to Biphasic Synovial Sarcoma

Symptoms & Phenotypes for Biphasic Synovial Sarcoma

Drugs & Therapeutics for Biphasic Synovial Sarcoma

Search Clinical Trials , NIH Clinical Center for Biphasic Synovial Sarcoma

Genetic Tests for Biphasic Synovial Sarcoma

Anatomical Context for Biphasic Synovial Sarcoma

MalaCards organs/tissues related to Biphasic Synovial Sarcoma:

38
Testis, Small Intestine

Publications for Biphasic Synovial Sarcoma

Articles related to Biphasic Synovial Sarcoma:

(show top 50) (show all 51)
# Title Authors Year
1
PAX8-positive Biphasic Synovial Sarcoma Expressing Hormonal Receptors. ( 28248726 )
2017
2
Biphasic synovial sarcoma of the epiglottis: Case report and literature review. ( 28689931 )
2017
3
Intravascular Biphasic Synovial Sarcoma: The Beneficial Role of Adjuvant Treatment Approach in the Pre-metastatic Stage. ( 27190730 )
2016
4
Biphasic synovial sarcoma with prominent cavernous hemangioma-like stroma. ( 27988941 )
2016
5
Monosomy 22 and partial loss of INI1 expression in a biphasic synovial sarcoma with an Ewing sarcoma-like poorly differentiated component: Report of a case. ( 27118264 )
2016
6
Biphasic synovial sarcoma of the hypopharynx. ( 25923284 )
2015
7
Primary biphasic synovial sarcoma of the right atrium. ( 26178188 )
2015
8
Biphasic synovial sarcoma in a 19-year-old pregnant woman: a case report. ( 25826519 )
2015
9
SS18-Bronchial Biphasic Synovial Sarcoma in an Octogenarian with Hemothorax. ( 24429587 )
2014
10
A non-joint tissue biphasic synovial sarcoma in a dog. ( 24447570 )
2014
11
Primary biphasic synovial sarcoma of gingiva: Report of a rare case. ( 24959041 )
2014
12
Superficial Soft Tissue Biphasic Synovial Sarcoma With Apocrine Differentiation in the Glandular Component: A Report of Two Cases. ( 23563252 )
2013
13
Pericardium: an exceedingly rare site for a primary biphasic synovial sarcoma. ( 22771650 )
2012
14
Primary intrathoracic biphasic synovial sarcoma. ( 22519387 )
2012
15
Biphasic synovial sarcoma arising from superior vena cava. ( 22419995 )
2012
16
Primary pulmonary biphasic synovial sarcoma: a case report and literature review. ( 22472156 )
2012
17
Biphasic synovial sarcoma in the cervical spine: Case report. ( 21605432 )
2011
18
Biphasic synovial sarcoma in mandibular region. ( 22529590 )
2011
19
Biphasic synovial sarcoma of the extremity: quadruple approach of isolated limb perfusion, surgical ablation, adipofascial perforator flap and radiation to avoid amputation. ( 21516237 )
2011
20
Primary pulmonary biphasic synovial sarcoma confirmed by molecular detection of a SYT-SSX2 fusion gene: report of 1 case. ( 20830232 )
2010
21
Cytogenetic heterogeneity in biphasic synovial sarcoma associated with telomere instability. ( 20113844 )
2010
22
Cryptic SYT/SXX1 fusion gene in high-grade biphasic synovial sarcoma with unique complex rearrangement and extensive BCL2 overexpression. ( 20082858 )
2010
23
Posterior mediastinal biphasic synovial sarcoma in a 12 year-old boy: a case report and review of literature. ( 21358103 )
2010
24
Biphasic synovial sarcoma. ( 18761552 )
2009
25
Biphasic synovial sarcoma of oral cavity. ( 18983797 )
2008
26
Biphasic synovial sarcoma of the abdominal wall. ( 16855839 )
2006
27
Biphasic synovial sarcoma of the posterior pharyngeal wall: a case report. ( 15971754 )
2005
28
Primary intrathoracic biphasic synovial sarcoma--a case report. ( 16477881 )
2005
29
Canine biphasic synovial sarcoma: case report and immunohistochemical characterization. ( 15192346 )
2004
30
Well-differentiated biphasic synovial sarcoma in the atlanto-occipital joint of a Holstein cow. ( 15557078 )
2004
31
Establishment and characterization of a biphasic synovial sarcoma cell line, SYO-1. ( 14744540 )
2004
32
Differential Ki67 and bcl-2 immunoexpression in solid-glandular and spindle cell components of biphasic synovial sarcoma: a double immunostaining assessment with cytokeratin and vimentin. ( 12010367 )
2002
33
MAGE antigen expression in monophasic and biphasic synovial sarcoma. ( 11957149 )
2002
34
Biphasic synovial sarcoma in a 13-month-old girl. ( 12151720 )
2002
35
Monophasic and biphasic synovial sarcomas abundantly express cancer/testis antigen NY-ESO-1 but not MAGE-A1 or CT7. ( 11668506 )
2001
36
Identification of syt-ssx fusion transcripts in both epithelial and spindle cell components of biphasic synovial sarcoma in small tissue samples isolated by membrane-based laser microdissection. ( 11561755 )
2001
37
Detection of SYT-SSX fusion transcripts in both epithelial and spindle cell areas of biphasic synovial sarcoma using laser capture microdissection. ( 10889911 )
2000
38
Pathologic quiz case. Pulmonary mass in a patient presenting with a hemothorax. Diagnosis: primary pulmonary biphasic synovial sarcoma. ( 10583938 )
1999
39
Primary pulmonary sarcoma with morphologic features of biphasic synovial sarcoma: a case report. ( 9539323 )
1998
40
Translocation (X;18) in a biphasic synovial sarcoma with morphologic features of neural differentiation. ( 9646030 )
1998
41
Masked t(X;18)(p11;q11) in a biphasic synovial sarcoma revealed by FISH and RT-PCR. ( 9739025 )
1998
42
Epithelial expression of glycodelin in biphasic synovial sarcomas. ( 9590122 )
1998
43
Biphasic synovial sarcoma of the peritoneal cavity with t(X;18) demonstrated by reverse transcriptase polymerase chain reaction. ( 9311017 )
1997
44
Primary biphasic synovial sarcoma of the pleura. ( 9415360 )
1997
45
Intraneural biphasic synovial sarcoma: an alternative "glandular" tumor of peripheral nerve. ( 8832556 )
1996
46
Biphasic synovial sarcoma in the small intestinal mesentery. ( 7539716 )
1995
47
Primary biphasic synovial sarcoma of the orbit. ( 1313455 )
1992
48
Fine needle aspiration cytology of biphasic synovial sarcoma of soft tissue. Report of a case with ultrastructural, immunohistologic and cytophotometric studies. ( 2296842 )
1990
49
Neuroendocrine differentiation in the glandular peripheral nerve sheath tumor. Pathologic distinction from the biphasic synovial sarcoma with glands. ( 2837100 )
1988
50
Monophasic and biphasic synovial sarcoma. An immunohistochemical study. ( 2441569 )
1987

Variations for Biphasic Synovial Sarcoma

Expression for Biphasic Synovial Sarcoma

Search GEO for disease gene expression data for Biphasic Synovial Sarcoma.

Pathways for Biphasic Synovial Sarcoma

Pathways related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 CDH1 DES MUC1 VIM
2 11.11 DES VIM
3
Show member pathways
10.81 DES VIM
4 10.21 CDH1 VIM

GO Terms for Biphasic Synovial Sarcoma

Biological processes related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.96 DES VIM
2 intermediate filament organization GO:0045109 8.62 DES VIM

Molecular functions related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 CDH1 DES EWSR1 VIM

Sources for Biphasic Synovial Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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