MCID: BPH002
MIFTS: 32

Biphasic Synovial Sarcoma malady

Cancer diseases category

Aliases & Classifications for Biphasic Synovial Sarcoma

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Aliases & Descriptions for Biphasic Synovial Sarcoma:

Name: Biphasic Synovial Sarcoma 8
Synovial Sarcoma, Biphasic 8 61
 
Biphasic Sarcoma of Synovium 8


Classifications:



External Ids:

Disease Ontology8 DOID:5492
SNOMED-CT56 18588008
NCIt39 C4279

Summaries for Biphasic Synovial Sarcoma

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MalaCards based summary: Biphasic Synovial Sarcoma, also known as synovial sarcoma, biphasic, is related to sarcoma and renal cell carcinoma. An important gene associated with Biphasic Synovial Sarcoma is MUC1 (mucin 1, cell surface associated), and among its related pathways are Adhesion and EGFR Signaling Pathway. The compounds eosin and s 100 have been mentioned in the context of this disorder. Affiliated tissues include small intestine and testis.

Related Diseases for Biphasic Synovial Sarcoma

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Diseases related to Biphasic Synovial Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 72)
idRelated DiseaseScoreTop Affiliating Genes
1sarcoma30.9CTAG1B, MAGEA1, SSX2, SS18, VIM, MUC1
2renal cell carcinoma10.4CDH1
3hidradenoma10.4MUC1
4syringoma10.4MUC1
5cystadenocarcinoma10.4MUC1
6adenomatoid tumor10.4VIM
7glomus tumor10.4VIM
8sarcoma, synovial10.3SS18, SSX2
9kidney hemangiopericytoma10.3SSX2, SS18
10pharyngitis10.3
11cervicitis10.3
12mediastinitis10.3
13peritonitis10.3
14testicular cancer10.2SSX2, MAGEA1, CTAG1B
15esophageal cancer10.2MAGEA1, CTAG1B
16seminoma10.2SSX2, MAGEA1
17tubular adenocarcinoma10.2MUC1, CDH1
18clear cell ependymoma10.2MUC1, VIM
19mesenchymal chondrosarcoma10.2VIM, MUC1
20spindle cell carcinoma10.2MUC1, VIM
21spindle cell sarcoma10.2MUC1, VIM
22sertoli cell tumor10.2VIM, MUC1
23epithelioid sarcoma10.2MUC1, VIM
24dermatofibrosarcoma protuberans10.2MUC1, VIM
25secretory meningioma10.1VIM, MUC1
26perineurioma10.1VIM, MUC1
27rhabdoid tumor10.1VIM, MUC1
28bladder cancer, somatic10.1MAGEA1, CDH1
29sex cord-gonadal stromal tumor10.1MUC1, VIM
30malignant mixed mullerian tumor10.1VIM, MUC1
31neuroendocrine tumor10.1CDH1, MUC1
32chordoma10.1VIM, MUC1
33angiosarcoma10.1VIM, MUC1
34giant cell tumor10.1VIM, MUC1
35abrikosov's tumor10.1MUC1, VIM
36malignant peripheral nerve sheath tumor10.1MUC1, VIM
37neurofibroma10.1MUC1, VIM
38pleomorphic adenoma10.1MUC1, VIM
39malignant fibroxanthoma10.1MUC1, VIM
40ependymoma10.1VIM, MUC1
41oxyphilic adenoma10.1MUC1, VIM
42leiomyosarcoma10.1MUC1, VIM
43neurilemmoma10.1VIM, MUC1
44breast cancer10.0CDH1, BCL2
45hemangiopericytoma10.0SSX2, MUC1, VIM
46reticulosarcoma10.0BCL2, MUC1
47leiomyoma10.0PAEP, VIM
48mesothelioma10.0VIM, MUC1
49ewing sarcoma10.0SS18, VIM
50papillary carcinoma10.0MUC1, CDH1

Graphical network of the top 20 diseases related to Biphasic Synovial Sarcoma:



Diseases related to biphasic synovial sarcoma

Symptoms for Biphasic Synovial Sarcoma

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Drugs & Therapeutics for Biphasic Synovial Sarcoma

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Drug clinical trials:

Search ClinicalTrials for Biphasic Synovial Sarcoma

Search NIH Clinical Center for Biphasic Synovial Sarcoma

Genetic Tests for Biphasic Synovial Sarcoma

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Anatomical Context for Biphasic Synovial Sarcoma

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MalaCards organs/tissues related to Biphasic Synovial Sarcoma:

31
Small intestine, Testis

Animal Models for Biphasic Synovial Sarcoma or affiliated genes

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Publications for Biphasic Synovial Sarcoma

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Articles related to Biphasic Synovial Sarcoma:

(show all 43)
idTitleAuthorsYear
1
Biphasic synovial sarcoma in a 19-year-old pregnant woman: a case report. (25826519)
2015
2
Primary biphasic synovial sarcoma of gingiva: Report of a rare case. (24959041)
2014
3
SS18-Bronchial Biphasic Synovial Sarcoma in an Octogenarian with Hemothorax. (24429587)
2014
4
A non-joint tissue biphasic synovial sarcoma in a dog. (24447570)
2014
5
Superficial Soft Tissue Biphasic Synovial Sarcoma With Apocrine Differentiation in the Glandular Component: A Report of Two Cases. (23563252)
2013
6
Pericardium: an exceedingly rare site for a primary biphasic synovial sarcoma. (22771650)
2012
7
Primary pulmonary biphasic synovial sarcoma: a case report and literature review. (22472156)
2012
8
Primary intrathoracic biphasic synovial sarcoma. (22519387)
2012
9
Biphasic synovial sarcoma arising from superior vena cava. (22419995)
2012
10
Biphasic synovial sarcoma in the cervical spine: Case report. (21605432)
2011
11
Biphasic synovial sarcoma of the extremity: quadruple approach of isolated limb perfusion, surgical ablation, adipofascial perforator flap and radiation to avoid amputation. (21516237)
2011
12
Biphasic synovial sarcoma in mandibular region. (22529590)
2011
13
Cryptic SYT/SXX1 fusion gene in high-grade biphasic synovial sarcoma with unique complex rearrangement and extensive BCL2 overexpression. (20082858)
2010
14
Primary pulmonary biphasic synovial sarcoma confirmed by molecular detection of a SYT-SSX2 fusion gene: report of 1 case. (20830232)
2010
15
Posterior mediastinal biphasic synovial sarcoma in a 12 year-old boy: a case report and review of literature. (21358103)
2010
16
Cytogenetic heterogeneity in biphasic synovial sarcoma associated with telomere instability. (20113844)
2010
17
Biphasic synovial sarcoma. (18761552)
2009
18
Biphasic synovial sarcoma of oral cavity. (18983797)
2008
19
Biphasic synovial sarcoma of the abdominal wall. (16855839)
2006
20
Biphasic synovial sarcoma of the posterior pharyngeal wall: a case report. (15971754)
2005
21
Primary intrathoracic biphasic synovial sarcoma--a case report. (16477881)
2005
22
Canine biphasic synovial sarcoma: case report and immunohistochemical characterization. (15192346)
2004
23
Establishment and characterization of a biphasic synovial sarcoma cell line, SYO-1. (14744540)
2004
24
Well-differentiated biphasic synovial sarcoma in the atlanto-occipital joint of a Holstein cow. (15557078)
2004
25
Biphasic synovial sarcoma in a 13-month-old girl. (12151720)
2002
26
MAGE antigen expression in monophasic and biphasic synovial sarcoma. (11957149)
2002
27
Identification of syt-ssx fusion transcripts in both epithelial and spindle cell components of biphasic synovial sarcoma in small tissue samples isolated by membrane-based laser microdissection. (11561755)
2001
28
Monophasic and biphasic synovial sarcomas abundantly express cancer/testis antigen NY-ESO-1 but not MAGE-A1 or CT7. (11668506)
2001
29
Detection of SYT-SSX fusion transcripts in both epithelial and spindle cell areas of biphasic synovial sarcoma using laser capture microdissection. (10889911)
2000
30
Pathologic quiz case. Pulmonary mass in a patient presenting with a hemothorax. Diagnosis: primary pulmonary biphasic synovial sarcoma. (10583938)
1999
31
Masked t(X;18)(p11;q11) in a biphasic synovial sarcoma revealed by FISH and RT-PCR. (9739025)
1998
32
Primary pulmonary sarcoma with morphologic features of biphasic synovial sarcoma: a case report. (9539323)
1998
33
Epithelial expression of glycodelin in biphasic synovial sarcomas. (9590122)
1998
34
Translocation (X;18) in a biphasic synovial sarcoma with morphologic features of neural differentiation. (9646030)
1998
35
Biphasic synovial sarcoma of the peritoneal cavity with t(X;18) demonstrated by reverse transcriptase polymerase chain reaction. (9311017)
1997
36
Primary biphasic synovial sarcoma of the pleura. (9415360)
1997
37
Intraneural biphasic synovial sarcoma: an alternative "glandular" tumor of peripheral nerve. (8832556)
1996
38
Biphasic synovial sarcoma in the small intestinal mesentery. (7539716)
1995
39
Primary biphasic synovial sarcoma of the orbit. (1313455)
1992
40
Fine needle aspiration cytology of biphasic synovial sarcoma of soft tissue. Report of a case with ultrastructural, immunohistologic and cytophotometric studies. (2296842)
1990
41
Neuroendocrine differentiation in the glandular peripheral nerve sheath tumor. Pathologic distinction from the biphasic synovial sarcoma with glands. (2837100)
1988
42
Monophasic and biphasic synovial sarcoma. An immunohistochemical study. (2441569)
1987
43
Keratin in the epithelial-like cells of classical biphasic synovial sarcoma. (6182681)
1982

Variations for Biphasic Synovial Sarcoma

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Expression for genes affiliated with Biphasic Synovial Sarcoma

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Search GEO for disease gene expression data for Biphasic Synovial Sarcoma.

Pathways for genes affiliated with Biphasic Synovial Sarcoma

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Pathways related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7CDH1, MUC1
29.7CDH1, MUC1
3
Show member pathways
9.7VIM, CDH1
4
Show member pathways
Development ERBB family signaling59
Development GDNF family signaling59
9.4CDH1, BCL2, MUC1
5
Show member pathways
Proteasome Degradation36
Immune response Antigen presentation by MHC class I59
9.3CDH1, BCL2, VIM
6
Show member pathways
9.0CDH1, BCL2, MUC1, VIM

Compounds for genes affiliated with Biphasic Synovial Sarcoma

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Compounds related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 61)
idCompoundScoreTop Affiliating Genes
1eosin4410.2MUC1, VIM
2s 1004410.2VIM, MUC1
3reticulin4410.2MUC1, VIM
4mucicarmine4410.2VIM, MUC1
5exisulind4410.1CDH1, BCL2
6aristolochic acid44 111.1VIM, CDH1
7slex4410.0CDH1, MUC1
8crcs449.9CDH1, MUC1
9b 723449.8VIM, MUC1, CDH1
10cytarabine44 50 1111.8VIM, MUC1, BCL2
11hematoxylin449.8CDH1, MUC1, VIM
12indole-3-carbinol449.8BCL2, CDH1
13sodium bisulfite449.8MAGEA1, CDH1
14dihydrotestosterone44 28 24 1112.8VIM, MUC1, CDH1
15hyaluronic acid44 2410.8CDH1, MUC1, VIM
16formaldehyde44 2410.8CDH1, VIM, MUC1
17vinblastine44 50 1111.8BCL2, CDH1, VIM
18folate449.8VIM, MUC1, CDH1
19thymidylate449.8VIM, BCL2, CDH1
20methotrexate50 44 1111.7VIM, CDH1, MUC1
21agar449.7CDH1, MUC1, VIM
22sulindac44 1110.7CDH1, BCL2
235fluorouracil449.7CDH1, MUC1, BCL2
24matrigel449.7CDH1, MUC1, VIM
25whey449.7MUC1, PAEP
26retinoid449.6BCL2, CDH1, VIM
2712-o-tetradecanoylphorbol 13-acetate449.6VIM, MUC1, CDH1
28etoposide44 50 60 1112.6CDH1, BCL2, VIM
29sb 20358044 6010.6VIM, BCL2, CDH1
30paclitaxel44 50 1111.5BCL2, CDH1, VIM
31rapamycin449.5VIM, CDH1, BCL2
32adriamycin449.5MUC1, BCL2, CDH1, VIM
33butyrate449.5VIM, MUC1, CDH1, BCL2
34actinomycin d449.4VIM, MUC1, BCL2
35wortmannin449.4VIM, CDH1, BCL2
36dexamethasone44 50 28 1112.4MUC1, BCL2, VIM, CDH1
37sialic acid449.3CDH1, MUC1, PAEP
38suberoylanilide hydroxamic acid449.3CDH1, PAEP, BCL2
39doxorubicin44 50 1111.2CDH1, VIM, BCL2
40glycogen44 2410.1VIM, MUC1, CDH1
41progestin449.0MUC1, PAEP, CDH1, VIM
42testosterone44 60 24 1112.0CDH1, VIM, PAEP, MUC1
43genistein44 28 60 1 24 1113.9CDH1, VIM, PAEP, BCL2
44paraffin448.8MAGEA1, VIM, MUC1, BCL2, CDH1
45tamoxifen44 50 28 1111.7MUC1, CDH1, VIM, BCL2, PAEP
46progesterone44 28 60 24 1112.6MUC1, VIM, PAEP, BCL2, CDH1
47vegf448.6BCL2, CDH1, MUC1, VIM, PAEP
48estrogen448.6MUC1, VIM, BCL2, CDH1, PAEP
49retinoic acid44 249.6PAEP, CDH1, VIM, MUC1, BCL2
505-aza-2deoxycytidine448.6CDH1, VIM, SSX2, CTAG1B, MAGEA1

GO Terms for genes affiliated with Biphasic Synovial Sarcoma

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Biological processes related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to toxic substanceGO:00096369.7CDH1, BCL2
2cellular component disassembly involved in execution phase of apoptosisGO:00069219.4CDH1, VIM
3response to drugGO:00424939.1CDH1, BCL2, SS18

Molecular functions related to Biphasic Synovial Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glycoprotein bindingGO:00019489.7CDH1, VIM

Sources for Biphasic Synovial Sarcoma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet