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MCID: BPL003
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Bipolar Disorder malady |
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83 drugs, 523 genes, 15 tissues, 744 related diseases, 27 phenotypes, 643 articles, clinical trials, genetic tests.
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Sources: 6Disease Ontology, 23MedlinePlus, 17Genetics Home Reference, 44Wikipedia, 22MalaCards See all sources Export this MalaCard |
MedlinePlus: Bipolar disorder is a serious mental illness. people who have it experience dramatic mood swings. they may go from overly energetic, "high" and/or irritable, to sad and hopeless, and then back again. they often have normal moods in between. the up feeling is called mania. the down feeling is depression.
bipolar disorder can run in families. it usually starts in late adolescence or early adulthood. if you think you may have it, tell your health care provider. a medical checkup can rule out other illnesses that might cause your mood changes.
untreated, bipolar disorder can result in damaged relationships, poor job or school performance, and even suicide. however, there are effective treatments: medicines and "talk therapy". a combination usually works best.
nih: national institute of mental health23
MalaCards: Bipolar Disorder, also known as manic disorder, is related to neuronitis and major depressive disorder. An important gene associated with Bipolar Disorder is DAOA (D-amino acid oxidase activator), and among its related pathways are Neuroactive ligand-receptor interaction and Metabolic pathways. The drugs amoxapine and imipramine and the compounds calcium and dopamine have been mentioned in the context of this disorder. Affiliated tissues include whole blood, brain and cortex, and related mouse phenotypes are behavior/neurological and nervous system. Disease Ontology: A mood disorder that involves alternating periods of mania and depression.6 Genetics Home Reference: PPM-X syndrome is a condition characterized by psychotic disorders (most commonly bipolar disorder), a pattern of movement abnormalities known as parkinsonism, and mild to severe intellectual disability. Other symptoms include increased muscle tone and exaggerated reflexes. Affected males may have enlarged testes (macro-orchidism). Not all affected individuals have all these symptoms, but most have intellectual disability. Males with this condition are typically more severely affected than females, who usually have only mild intellectual disability.17 Wikipedia: Bipolar disorder or bipolar affective disorder (historically known as manic-depressive disorder) is a...44 more... |
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Sources: 6Disease Ontology, 16GeneTests, 32Novoseek , 23MedlinePlus, 43UMLS, 8DISEASES, 40SNOMED-CT, 27NCIt, 19ICD9CM, 24MeSH See all sources |
Aliases & Descriptions:
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for bipolar disorder Drug clinical trials:Search ClinicalTrials for bipolar disorder Search NIH Clinical Center for bipolar disorder Search CenterWatch for bipolar disorder Inferred drug relations via UMLS/NDF-RT:43 28 alprazolam, amitriptyline, amitriptyline hydrochloride, amoxapine, bupropion, bupropion hydrobromide, bupropion hydrochloride, buspirone, buspirone hydrochloride, carbamazepine, citalopram, citalopram hydrobromide, clomipramine, clomipramine hydrochloride, clonazepam, clozapine, desipramine, desipramine hydrochloride, divalproex, divalproex sodium, doxepin, doxepin hydrochloride, escitalopram, escitalopram oxalate, fluoxetine, fluoxetine hydrochloride, fluvoxamine, fluvoxamine maleate, gabapentin, gabapentin enacarbil, hypericum perforatum (st. john's wort), imipramine, imipramine hydrochloride, imipramine pamoate, isocarboxazid, isoflurane, kava, kava extract, lamotrigine, lithium, lithium (as citrate), lithium carbonate, lithium citrate, lorazepam, maprotiline, maprotiline hydrochloride, methylphenidate, methylphenidate hydrochloride, mirtazapine, nefazodone, nortriptyline, nortriptyline hydrochloride, olanzapine, paroxetine, paroxetine hydrochloride, phenelzine, phenelzine sulfate, pramipexole, pramipexole dihydrochloride, protriptyline, protriptyline hydrochloride, quetiapine, quetiapine fumarate, risperidone, selegiline, selegiline hydrochloride, sertraline, sertraline hydrochloride, temazepam, tiagabine, tiagabine hydrochloride, topiramate, tranylcypromine, tranylcypromine sulfate, trazodone, trazodone hydrochloride, tricyclic antidepressant [epc], trimipramine, trimipramine maleate, valproate sodium, valproic acid, venlafaxine, venlafaxine hydrochloride |
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Sources: 16GeneTests See all sources |
Genetic tests related to bipolar disorder:
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to bipolar disorder:22Whole blood, Brain, Cortex, Cerebellum, Monocytes, T cells, B lymphoblasts, B cells, Prefrontal cortex, Cingulate cortex, Temporal lobe, Thalamus, Amygdala, Adrenal cortex, Pituitary
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to bipolar disorder:25 (show all 27)
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Sources: 35PubMed See all sources |
Articles related to bipolar disorder:(show top 50) (show all 643)
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Sources: 1BioGPS See all sources |
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Sources: 20KEGG, 3Cell Signaling Technology, 36QIAGEN, 10EMD Millipore, 41Thomson Reuters, 38Reactome, 34PharmGKB See all sources |
Pathways related to bipolar disorder according to GeneDecks:(show top 50) (show all 136)
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Sources: 32Novoseek , 9DrugBank, 18HMDB, 42Tocris Bioscience, 34PharmGKB See all sources |
Compounds related to bipolar disorder according to GeneDecks:(show top 50) (show all 561)
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Sources: 12Gene Ontology See all sources |
Cellular components related to bipolar disorder according to GeneDecks:(show all 31)
Biological processes related to bipolar disorder according to GeneDecks:(show top 50) (show all 89)
Molecular functions related to bipolar disorder according to GeneDecks:(show all 24)
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