Aliases & Classifications for Birth Defects

Summaries for Birth Defects

MedlinePlus : 41 a birth defect is a problem that happens while a baby is developing in the mother's body. most birth defects happen during the first 3 months of pregnancy. one out of every 33 babies in the united states is born with a birth defect. a birth defect may affect how the body looks, works or both. some birth defects like cleft lip or neural tube defects are structural problems that can be easy to see. to find others, like heart defects, doctors use special tests. birth defects can vary from mild to severe. some result from exposures to medicines or chemicals. for example, alcohol abuse can cause fetal alcohol syndrome. infections during pregnancy can also result in birth defects. for most birth defects, the cause is unknown. some birth defects can be prevented. taking folic acid can help prevent some birth defects. talk to your doctor about any medicines you take. some medicines can cause serious birth defects. babies with birth defects may need surgery or other medical treatments. today, doctors can diagnose many birth defects in the womb. this enables them to treat or even correct some problems before the baby is born. centers for disease control and prevention

MalaCards based summary : Birth Defects is related to neural tube defects, folate-sensitive and alcohol-related birth defect. An important gene associated with Birth Defects is CRBN (Cereblon), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Diseases of metabolism. The drugs Clozapine and Moxonidine have been mentioned in the context of this disorder. Affiliated tissues include heart, myeloid and brain.

CDC : 3 Every 4.5 minutes, a baby is born with a birth defect. Major birth defects are conditions present at birth that cause structural changes in one or more parts of the body.

Related Diseases for Birth Defects

Diseases related to Birth Defects via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)
id Related Disease Score Top Affiliating Genes
1 neural tube defects, folate-sensitive 30.7 MTR MTRR
2 alcohol-related birth defect 12.1
3 maternal hyperthermia induced birth defects 11.9
4 fetal alcohol spectrum disorder 11.4
5 fetal alcohol syndrome 11.2
6 gastroschisis 11.0
7 neural tube defects 11.0
8 congenital diaphragmatic hernia 10.9
9 holoprosencephaly 10.8
10 cloacal exstrophy 10.8
11 esophageal atresia 10.8
12 biliary atresia 10.8
13 heterotaxy 10.8
14 phocomelia 10.8
15 sirenomelia 10.8
16 triploidy 10.8
17 cleft lip/palate 10.8
18 vacterl association 10.7
19 corpus callosum agenesis 10.7
20 fetal retinoid syndrome 10.7
21 iniencephaly 10.7
22 schizencephaly 10.6
23 tibial hemimelia 10.6
24 hemifacial microsomia 10.6
25 myhre syndrome 10.6
26 cutis marmorata telangiectatica congenita 10.6
27 craniosynostosis 10.6
28 myelomeningocele 10.6
29 imperforate anus 10.6
30 polydactyly 10.6
31 rubella 10.6
32 omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects complex 10.6
33 pallister-killian mosaic syndrome 10.6
34 tracheal agenesis 10.6
35 neu-laxova syndrome 1 10.4
36 orofacial cleft 6 10.4
37 prune belly syndrome 10.4
38 mowat-wilson syndrome 10.4
39 vertical talus, congenital 10.4
40 orofacial cleft 10 10.4
41 rapp-hodgkin syndrome 10.4
42 orofacial cleft 5 10.4
43 short syndrome 10.4
44 wilms tumor susceptibility-5 10.4
45 coloboma, ocular 10.4
46 cleft lip/palate-ectodermal dysplasia syndrome 10.4
47 hydrolethalus syndrome 10.4
48 moebius syndrome 10.4
49 coloboma, ocular, autosomal recessive 10.4
50 orofacial cleft 11 10.4

Graphical network of the top 20 diseases related to Birth Defects:



Diseases related to Birth Defects

Symptoms & Phenotypes for Birth Defects

Drugs & Therapeutics for Birth Defects

Drugs for Birth Defects (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1627)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clozapine Approved Phase 4 5786-21-0 2818
2
Moxonidine Approved Phase 4 75438-57-2 4810
3
Olanzapine Approved, Investigational Phase 4,Phase 2 132539-06-1 4585
4
Thrombin Approved Phase 4,Phase 3,Phase 2,Phase 1
5
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-84-3 187
6
Oxybutynin Approved, Investigational Phase 4 5633-20-5 4634
7
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 657-24-9 14219 4091
8
Saxagliptin Approved Phase 4,Phase 3,Phase 1 361442-04-8 11243969
9
Sevelamer Approved Phase 4,Phase 3,Phase 2 52757-95-6, 152751-57-0 3085017
10
Sulfamethoxazole Approved Phase 4,Phase 3,Phase 2,Phase 1 723-46-6 5329
11
Trimethoprim Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 738-70-5 5578
12
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 58-61-7 60961
13
Dipyridamole Approved Phase 4,Phase 3 58-32-2 3108
14
Regadenoson Approved Phase 4,Phase 2,Phase 1 313348-27-5 219024
15
Entecavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 142217-69-4 153941
16
Polidocanol Approved Phase 4 9002-92-0
17
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
18
Milnacipran Approved Phase 4,Phase 3 92623-85-3 65833
19
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
20
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
21
Zolpidem Approved Phase 4 82626-48-0 5732
22 Zotepine Approved Phase 4 26615-21-4
23
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-02-2 5743
24
Levodopa Approved Phase 4,Phase 3,Phase 2,Phase 1 59-92-7 6047
25
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-78-2 2244
26
Telbivudine Approved, Investigational Phase 4,Phase 1,Phase 2 3424-98-4 159269
27
Ramipril Approved Phase 4,Phase 3,Phase 2,Phase 1 87333-19-5 5362129
28
Ropivacaine Approved Phase 4,Phase 2 84057-95-4 71273 175805
29
Emtricitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 143491-57-0 60877
30
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Phase 1 103-90-2 1983
31
Ibuprofen Approved Phase 4,Phase 3,Phase 2,Phase 1 15687-27-1 3672
32
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2180-92-9, 38396-39-3 2474
33
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 51-43-4 5816
34
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3 76-42-6 5284603
35 Racepinephrine Approved Phase 4,Phase 2,Phase 3,Phase 1
36
Desflurane Approved Phase 4,Phase 2 57041-67-5 42113
37
Isoflurane Approved, Vet_approved Phase 4,Phase 2,Phase 3 26675-46-7 3763
38
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 28523-86-6 5206
39
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
40
Norepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-41-2 439260
41
Oxymetazoline Approved Phase 4,Phase 3,Phase 1 1491-59-4 4636
42
Phenylephrine Approved Phase 4,Phase 3,Phase 1 59-42-7 6041
43
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
44
Adefovir Dipivoxil Approved, Investigational Phase 4,Phase 3,Phase 1 142340-99-6 60871
45
Tetracycline Approved, Vet_approved Phase 4,Phase 1 60-54-8 5353990
46
Candesartan Approved Phase 4,Phase 2,Early Phase 1 139481-59-7 2541
47
Cilnidipine Approved Phase 4,Phase 2 132203-70-4 5282138
48
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
49
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 2078-54-8 4943
50
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 137-58-6 3676

Interventional clinical trials:

(show top 50) (show all 8675)

id Name Status NCT ID Phase Drugs
1 Cohort Prospective Study of Children With Head and Neck Cystic Malformation Who Are Treated With Intracystic OK432 Unknown status NCT01699347 Phase 4 Intracystic injection of OK432 under US guiding
2 Demineralized Bone Matrix in Opening Wedge Osteotomy for Hallux Valgus Deformity Unknown status NCT02388438 Phase 4
3 Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease Unknown status NCT00188188 Phase 4 quinipril
4 Alleviating the Metabolic Side Effects of Antipsychotic Medications Unknown status NCT01567124 Phase 4 Moxonidine;Placebo;Moxonidine;Placebo
5 Curcumin for Type 2 Diabetic Patients Unknown status NCT01052597 Phase 4 curcumin
6 Impact of Raltegravir on the Viral Reservoirs Unknown status NCT01249560 Phase 4
7 Effect of Human Thrombin With Gelatin Matrix on Perioperative Blood Loss in Scoliosis Surgery Unknown status NCT01451788 Phase 4
8 Effect of Botulinum Toxin in Neurogenic Bladders in Children With Myelomeningocele Unknown status NCT00175123 Phase 4 Botulinum A toxin
9 Effect of Saxagliptin on Pre-Diabetes Mellitus and Obesity Unknown status NCT01960205 Phase 4 Saxagliptin;saxagliptin;metformin
10 How Bone is Made in Children Receiving Dialysis Unknown status NCT01799317 Phase 4 Vitamin D2
11 Cotrimoxazole Prophylaxis Cessation Study Among Stabilized HIV-Infected Adult Patients on HAART in Entebbe, Uganda Unknown status NCT00674921 Phase 4 cotrimoxazole;Placebo
12 Evaluate the Effects of Formoterol and Beclomethasone Dipropionate Combination Therapy on Small Airways Function Unknown status NCT01466712 Phase 4 Tiotropium + formoterol/beclometasone;tiotropium + placebo
13 Diagnostic Benefits of HyperQTM vs. Conventional ECG Stress Test. Comparison of HyperQ vs. Stress ECG in Women Before Angiography Unknown status NCT00850486 Phase 4
14 Metformin for the Treatment of Unexplained Oligozspermia Unknown status NCT01529177 Phase 4 Metformin / clomid / hCG;Clomiphene citrate / hCG
15 Lexiscan(TM) Rb-82 Myocardial Perfusion PET: A Comparison With Dipyridamole Stress Unknown status NCT00808314 Phase 4 Rest/Dipyridamole Stress Rb-82 Myocardial Perfusion PET/CT;Rest/Lexiscan(TM) Stress Rb-82 Myocardial Perfusion PET
16 Entecavir Plus Tenofovir Combination in Subjects With Multi-drug Resistant Chronic Hepatitis B Virus Infection Unknown status NCT01594905 Phase 4 Entecavir + Tenofovir (MDR group)
17 Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia Unknown status NCT01718340 Phase 4 Metformin
18 Impaired Decision Making in Pedophilic Offenders Unknown status NCT01541150 Phase 4
19 Lovaza Mechanisms of Action Unknown status NCT01301794 Phase 4
20 Cardiovascular Effects of Metformin on Obesity Unknown status NCT01910246 Phase 4 Metformin
21 An Assessment of Intra-lesional 3% Polidocanol Solution in the Treatment of Digital Myxoid Cyst Unknown status NCT02154789 Phase 4 polidocanol
22 Study of Fibromyalgia Treated With Milnacipran Unknown status NCT01125423 Phase 4 Milnacipran
23 Characterization of Hyperparathyroidism and Vitamin D Deficiency in Obesity Unknown status NCT00288873 Phase 4 Ergocalciferol;Cholecalciferol
24 Risperidone and Zotepine in the Treatment of Delirium Unknown status NCT00622011 Phase 4 Risperidone and Zolpidem for delirium
25 Rationale, Design and Methods for the Early Surgery in Infective Endocarditis Study (ENDOVAL) Unknown status NCT00624091 Phase 4
26 Comparing Pain and Swelling After Surgical Extraction of Mandibular Third Molar in Dexamethasone Injection and Without Corticosteroid Methods Unknown status NCT01896427 Phase 4 21-benzyloxy-9alpha-fluoro-16alpha-methylpregna-1,4-dien-11beta,17alpha-diol-3,20-dione
27 Significance of Regional Ventriculo-arterial Coupling in Patients With Chronic Heart Failure Unknown status NCT01156207 Phase 4 Aliskiren
28 Dopamine Treatment in Children With Cerebral Palsy With Dystonia- A Double Blind Controlled Study Unknown status NCT01361373 Phase 4 L- DOPA;placebo
29 The Effect of Biannual Monitoring With Magnetic Resonance Imaging (MRI), X-ray, or Usual Care on Treatment for Inflammatory Arthritis Unknown status NCT00808496 Phase 4
30 Effects of Atorvastatin Treatment on Left Ventricular Diastolic Function in Peritoneal Dialysis Patients Unknown status NCT01503671 Phase 4 Atorvastatin
31 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4 Microbubbles
32 Efficacy and Safety Study of Telbivudine to Prevent Perinatal Transmission Unknown status NCT00939068 Phase 4 Telbivudine
33 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4 ramipril;rosuvastatin;placebo
34 Home Infusors for Analgesia After Foot Surgery Unknown status NCT00600899 Phase 4
35 Improved Diagnosis of Congenital Heart Disease by Magnetic Resonance Imaging Using Vasovist Unknown status NCT00668824 Phase 4 Vasovist
36 Emtricitabine for Prevention of Vertical Transmission of HBV in Chinese Pregnant HBsAg Positive Patients Unknown status NCT02327715 Phase 4 Emtricitabine
37 Emtricitabine for Naive Chinese Pregnant Chronic Hepatitis B Patients Unknown status NCT02327702 Phase 4 Emtricitabine
38 Metformin and Gestational Diabetes in High-risk Patients: a RCTs Unknown status NCT00883259 Phase 4 Metformin
39 Serum Level Measurement of Oral Paracetamol and Oral Ibuprofen for Patent Ductus Arteriosus Treatment in Preterm Infants Unknown status NCT01544972 Phase 4 Oral paracetamol;Oral ibuprofen
40 Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart Surgery Unknown status NCT01536717 Phase 4 Articaine hydrochloride 2% solution;Sodium Chloride
41 Pulmonary Mechanics During Minimally Invasive Repair of Pectus Excavatum Unknown status NCT01486953 Phase 4 Desflurane;Sevoflurane
42 A Pilot Trial of Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients Unknown status NCT02203630 Phase 4 Phenylephrine;Norepinephrine
43 Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery Stenosis Unknown status NCT02224209 Phase 4
44 A Post-marketing Research on Jinyebaidu Granule in Treating Patients With Acute Upper Respiratory Infection Unknown status NCT02539277 Phase 4 Jinyebaidu granule;Fufangshuanghua granule;Jinyebaidu granule placebo;Fufangshuanghua granule placebo
45 Study of Effects and Safety Between Adefovir Dipivoxil Plus Polyene Phosphatidylcholine Versus Adefovir Dipivoxil Alone in Chronic Hepatitis B Patients Unknown status NCT01436539 Phase 4 Adefovir Dipivoxil and polyene phosphatidylcholine;Adefovir Dipivoxil
46 Randomised Double Blind Crossover Placebo Controlled Study to Evaluate the Efficacy of Tetracycline in Epidermolysis Bullosa Unknown status NCT00336154 Phase 4 tetracyclin
47 Comparison of the Ahmed Glaucoma Valve FP7 and FP8 in Pediatric Glaucoma Unknown status NCT01494974 Phase 4
48 CCB Safety Study in Treatment of Hypertension of ADPKD Unknown status NCT00541853 Phase 4 Candesartan;Candesartan and Cilnidipine;Candesartan plus non-CCB agents
49 Therapeutic Effects of Customized Insoles on Children With Flat Foot Unknown status NCT02414087 Phase 4
50 Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery Unknown status NCT02447796 Phase 4 Propofol;Dexmedetomidine

Search NIH Clinical Center for Birth Defects

Genetic Tests for Birth Defects

Anatomical Context for Birth Defects

MalaCards organs/tissues related to Birth Defects:

39
Heart, Myeloid, Brain, Bone, Breast, Kidney, Lung

Publications for Birth Defects

Articles related to Birth Defects:

(show top 50) (show all 161)
id Title Authors Year
1
Committee Opinion No. 717 Summary: Sulfonamides, Nitrofurantoin, and Risk of Birth Defects. ( 28832479 )
2017
2
Prevalence of microcephaly in an Australian population-based birth defects register, 1980-2015. ( 28446117 )
2017
3
Changing trends in the prevalence of anencephaly in Liaoning province of Northeast China from 2006-2015: data from a population-based birth defects registry. ( 28514736 )
2017
4
Changing trends in the prevalence of anencephaly in Liaoning province of Northeast China from 2006-2015: data from a population-based birth defects registry. ( 28881776 )
2017
5
Using latent class cluster analysis to screen high risk clusters of birth defects between 2009 and 2013 in Northwest China. ( 28761054 )
2017
6
Identifying birth defects in automated data sources in the Vaccine Safety Datalink. ( 28054412 )
2017
7
Pediatric cancer risk in association with birth defects: A systematic review. ( 28749971 )
2017
8
Prevalence trends of selected major birth defects: A multi-state population-based retrospective study, United States, 1999 to 2007. ( 28905502 )
2017
9
Magnetic resonance imaging study of eye congenital birth defects in mouse model. ( 28848319 )
2017
10
Under-reporting of major birth defects in Northwest Russia: a registry-based study. ( 28853333 )
2017
11
Notes from the Field: Zika Virus-Associated Neonatal Birth Defects Surveillance - Texas, January 2016-July 2017. ( 28796762 )
2017
12
Inactivated influenza vaccination in first trimester does not appear to increase risk of birth defects. ( 28918399 )
2017
13
Response to Letters to the Editor Birth Defects Outcomes in Pregnancies Conceived through In Vitro Fertilization. ( 28815658 )
2017
14
Committee Opinion No. 717: Sulfonamides, Nitrofurantoin, and Risk of Birth Defects. ( 28832488 )
2017
15
Birth defects after use of antithyroid drugs in early pregnancy: a Swedish nationwide study. ( 28780518 )
2017
16
Major Birth Defects after Vaccination Reported to the Vaccine Adverse Event Reporting System (VAERS), 1990 to 2014. ( 28762675 )
2017
17
Raised Frequency of Central Nervous System Malformations Related to Zika Virus Infection in Two Birth Defects Surveillance Systems in BogotA! and Cali, Colombia. ( 28678053 )
2017
18
Announcement: National Birth Defects Prevention Month and Folic Acid Awareness Week - January 2017. ( 28056002 )
2017
19
Causes of major birth defects still largely unknown. ( 28656835 )
2017
20
Thyroid Medication Use and Birth Defects in the National Birth Defects Prevention Study. ( 28758357 )
2017
21
Birth Defects Among Fetuses and Infants of US Women With Evidence of Possible Zika Virus Infection During Pregnancy. ( 27960197 )
2017
22
Evaluation of the Sensitivity and Accuracy of Birth Defects Indicators on the 2003 Revision of the U.S. Birth Certificate: Has Data Quality Improved? ( 27859434 )
2017
23
Birth defects in juvenile Wistar rats after exposure to immunosuppressive drugs during pregnancy. ( 27097725 )
2017
24
Congenital Malformations to Birth Defects - The Indian Scenario. ( 28737144 )
2017
25
Raised Frequency of Microcephaly Related to Zika Virus Infection in Two Birth Defects Surveillance Systems in BogotA! and Cali, Colombia. ( 28914749 )
2017
26
Safety of inadvertent anthrax vaccination during pregnancy: An analysis of birth defects in the U.S. military population, 2003-2010. ( 28673484 )
2017
27
Selected birth defects among males following the United States terrorist attacks of 11 September 2001. ( 28722355 )
2017
28
Corrigendum: The Survey of Birth Defects Rate Based on Birth Registration System. ( 27569248 )
2016
29
Brazil asks whether Zika acts alone to cause birth defects. ( 27466104 )
2016
30
Reporting of birth defects in SART CORS: time to rely on data linkage. ( 27343954 )
2016
31
Ondansetron Use in Pregnancy andOndansetron Use in Pregnancy and Birth Defects: A Systematic Review. ( 27454720 )
2016
32
Modeling craniofacial and skeletal congenital birth defects to advance therapies. ( 27346519 )
2016
33
Molecular Insights into Development in Humans: Studies in Normal Development and Birth Defects. ( 27514997 )
2016
34
Folic acid supplementation, birth defects, and adverse pregnancy outcomes in Chinese women: a population-based mega-cohort study. ( 27968911 )
2016
35
Disinfection By-Product Exposures and the Risk of Specific Cardiac Birth Defects. ( 27518881 )
2016
36
Prevalence of congenital limb defects: Data from birth defects registries in three provinces in Southern Thailand. ( 27580948 )
2016
37
Associations between maternal periconceptional exposure to secondhand tobacco smoke and major birth defects. ( 27443814 )
2016
38
Maternal autoimmune disease and birth defects in the National Birth Defects Prevention Study. ( 27891777 )
2016
39
Swine flu vaccine is unlikely to raise risk of overall birth defects, study finds. ( 27658945 )
2016
40
Birth defects and neonatal morbidity caused by teratogen exposure after the embryonic period. ( 27511745 )
2016
41
Fine particle-induced birth defects: Impacts of size, payload, and beyond. ( 27581067 )
2016
42
Safety of the 2010-11, 2011-12, 2012-13, and 2013-14 seasonal influenza vaccines in pregnancy: Birth defects, spontaneous abortion, preterm delivery, and small for gestational age infants, a study from the cohort arm of VAMPSS. ( 27449682 )
2016
43
Ocular finding in Zika virus infectionResponse letter: Serological evidence confirms the presumed diagnosis of Zika virus congenital infection in infants with microcephaly and ocular findingsZika virus outbreak in the Americas: the need for novel mosquito control methodsThe Brazilian Zika virus strain causes birth defects in experimental modelsOphthalmologic findings in infants with microcephaly and presumable intra-uterus Zika virus infectionZika virus in Brazil and macular atrophy in a child with microcephalyVariables related to the ophthalmoscopic findings identified in infants with presumed Zika virus congenital infection. ( 27626161 )
2016
44
US urges Puerto Rico to start aerial spraying to reduce risk of birth defects. ( 27401608 )
2016
45
Patterns and risk factors of birth defects in rural areas of south-eastern Gabon. ( 27859649 )
2016
46
An opportunity to address the genetic causes of birth defects. ( 27925620 )
2016
47
The impact of thalidomide use in birth defects in Brazil. ( 27638330 )
2016
48
Editorial advances in population-based birth defects surveillance, epidemiology, and public health practice. ( 27891776 )
2016
49
Association between antibiotic use among pregnant women with urinary tract infections in the first trimester and birth defects, National Birth Defects Prevention Study 1997 to 2011. ( 27891788 )
2016
50
Hypospadias and maternal exposure to atrazine via drinking water in the National Birth Defects Prevention study. ( 27422386 )
2016

Variations for Birth Defects

Expression for Birth Defects

Search GEO for disease gene expression data for Birth Defects.

Pathways for Birth Defects

Pathways related to Birth Defects according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.15 AMN MTR MTRR
2
Show member pathways
11.31 AMN MTR MTRR
3 11.13 FGFR2 NTRK3
4 10.91 FGFR2 NTRK3
5 10.14 AMN MTR MTRR
6
Show member pathways
9.73 MTR MTRR

GO Terms for Birth Defects

Biological processes related to Birth Defects according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular response to retinoic acid GO:0071300 9.37 FGFR2 NTRK3
2 cellular amino acid biosynthetic process GO:0008652 9.32 MTR MTRR
3 response to axon injury GO:0048678 9.26 MTR NTRK3
4 methionine biosynthetic process GO:0009086 9.16 MTR MTRR
5 sulfur amino acid metabolic process GO:0000096 8.96 MTR MTRR
6 cobalamin metabolic process GO:0009235 8.8 AMN MTR MTRR

Molecular functions related to Birth Defects according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.62 FGFR2 NTRK3

Sources for Birth Defects

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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