MCID: BZR001
MIFTS: 32

Bizarre Leiomyoma malady

Category: Cancer diseases

Aliases & Classifications for Bizarre Leiomyoma

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Aliases & Descriptions for Bizarre Leiomyoma:

Name: Bizarre Leiomyoma 10 12 65
Pleomorphic Leiomyoma 10
 
Symplastic Leiomyoma 10
Atypical Leiomyoma 10

Classifications:



External Ids:

Disease Ontology10 DOID:5127
SNOMED-CT59 48897006
NCIt42 C4257
UMLS65 C0334478

Summaries for Bizarre Leiomyoma

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MalaCards based summary: Bizarre Leiomyoma, also known as pleomorphic leiomyoma, is related to uterine corpus bizarre leiomyoma and leukemia. An important gene associated with Bizarre Leiomyoma is ACTC1 (Actin, Alpha, Cardiac Muscle 1), and among its related pathways are BARD1 signaling events and GADD45 Pathway. Affiliated tissues include cortex, colon and liver, and related mouse phenotypes are muscle and no phenotypic analysis.

Related Diseases for Bizarre Leiomyoma

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Diseases related to Bizarre Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 165)
idRelated DiseaseScoreTop Affiliating Genes
1uterine corpus bizarre leiomyoma12.6
2leukemia10.4
3benign multicystic peritoneal mesothelioma10.3ACTC1, PGR
4adult mesoblastic nephroma10.3ACTC1, PGR
5ovarian mucinous cystadenocarcinoma10.3ACTC1, PCNA
6thymus lipoma10.2ACTC1, PGR
7obesity10.2
8cataract10.2
9hydrocephalus10.2
10nephrolithiasis10.2
11thalassemia10.2
12corneal disease10.2
13sarcoma10.2
14respiratory failure10.2
15choroiditis10.2
16neonatal diabetes mellitus10.2
17obstructive hydrocephalus10.2
18melanotic neuroectodermal tumor10.2
19gallbladder cancer10.2
20retinitis10.2
21childhood leukemia10.2
22breast carcinoma in situ10.2
23diabetic macular edema10.2
24hypotonia10.2
25oral tuberculosis10.2ACTC1, PGR
26pyridoxal 5'-phosphate-dependent epilepsy10.2ACTC1, TP53
27secretory meningioma10.2PCNA, PGR
28prostatic cyst10.2PCNA, PGR
29pulmonary immaturity10.2ACTC1, TP53
30syringocystadenoma papilliferum10.2ACTC1, TP53
31cervical adenoid cystic carcinoma10.2PCNA, PGR
32small intestine leiomyosarcoma10.2ACTC1, TP53
33proliferative fasciitis10.2ACTC1, TP53
34metachronous kidney wilms' tumor10.2PGR, TP53
35ovary neuroendocrine neoplasm10.2PGR, TP53
36hypothyroidism due to deficient transcription factors involved in pituitary development or function10.2ACTC1, TP53
37ovarian mesodermal adenosarcoma10.2PGR, TP53
38pituitary stalk meningioma10.2PGR, TP53
39cystadenoma10.2PGR, TP53
40uterine corpus adenosarcoma10.1PGR, TP53
41corneal neovascularization10.1PGR, TP53
42pyelonephritis10.1PGR, TP53
43exposure keratitis10.1PGR, TP53
44skull base meningioma10.1PGR, TP53
45internal auditory canal lipoma10.1PGR, TP53
46immune system cancer10.1PGR, TP53
47osteoblastoma10.1PGR, TP53
48head and neck carcinoma10.1PGR, TP53
49peritoneal cystic mesothelioma10.1PGR, TP53
50fallopian tube leiomyosarcoma10.1PGR, TP53

Graphical network of the top 20 diseases related to Bizarre Leiomyoma:



Diseases related to bizarre leiomyoma

Symptoms for Bizarre Leiomyoma

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Drugs & Therapeutics for Bizarre Leiomyoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Bizarre Leiomyoma

Genetic Tests for Bizarre Leiomyoma

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Anatomical Context for Bizarre Leiomyoma

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MalaCards organs/tissues related to Bizarre Leiomyoma:

33
Cortex, Colon, Liver, Lung, Uterus

Animal Models for Bizarre Leiomyoma or affiliated genes

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MGI Mouse Phenotypes related to Bizarre Leiomyoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.1ACTC1, CDKN2A, PGR, TP53
2MP:00030127.7CDKN2A, PCNA, PGR, TP53

Publications for Bizarre Leiomyoma

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Articles related to Bizarre Leiomyoma:

(show all 21)
idTitleAuthorsYear
1
Compound composite odontoma. (27194882)
2016
2
Turner Syndrome and apparent absent uterus: a case report and review of the literature. (23443264)
2013
3
Does farm environment protect against type 1 diabetes mellitus? (23444292)
2013
4
Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells. (21423269)
2011
5
Asthma as a clinical presentation of cor triatriatum sinister in a Brazilian Amazon child: a case report. (19448560)
2009
6
Beta-cell function in individuals carrying the mitochondrial tRNA leu (UUR) mutation. (17198195)
2007
7
Mesenteric cystic lymphangioma: a prenatal diagnostic challenge. (17471606)
2007
8
An unusual case of superficial lymphangioma of the right foot. (18093452)
2007
9
15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism. (16939878)
2006
10
Rapidly growing dysembryoplastic neuroepithelial tumor: case report. (17277670)
2006
11
Synthesis of 7-oxasphingosine and -ceramide analogues and their evaluation in a model for apoptosis. (17191816)
2004
12
APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase. (15121899)
2004
13
Extended interval between enzyme therapy infusions for adult patients with Gaucher's disease type 1. (12867687)
2003
14
Type III intermediate filament proteins interact with four-way junction DNA and facilitate its cleavage by the junction-resolving enzyme T7 endonuclease I. (12823903)
2003
15
Biological agents as weapons 1: smallpox and botulism. (12056996)
2002
16
Presumptive monosomy 21 with neuronal migration disorder re-diagnosed as de novo unbalanced translocation t(18p;21q) by fluorescence in situ hybridisation. (12150215)
2002
17
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation. (12060769)
2002
18
Somatic mutation of PTEN in bladder carcinoma. (10360673)
1999
19
Parameters of the fibrinolytic system in patients undergoing BMT: elevation of PAI-1 in veno-occlusive disease. (7889007)
1994
20
Liver or lung colonization by F9 teratocarcinoma cells follows specific interactions with the target organ. (1617234)
1992
21
Fine structural changes in the cerebellar cortex in kinky hair disease. (1028277)
1976

Variations for Bizarre Leiomyoma

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Expression for genes affiliated with Bizarre Leiomyoma

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Search GEO for disease gene expression data for Bizarre Leiomyoma.

Pathways for genes affiliated with Bizarre Leiomyoma

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Pathways related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
19.3PCNA, TP53
29.3PCNA, TP53
39.3PCNA, TP53
49.3PCNA, TP53
59.3PCNA, TP53
69.0CDKN2A, TP53
7
Show member pathways
9.0CDKN2A, TP53
89.0CDKN2A, TP53
99.0CDKN2A, TP53
109.0CDKN2A, TP53
11
Show member pathways
9.0CDKN2A, TP53
129.0CDKN2A, TP53
138.5CDKN2A, PCNA, TP53
14
Show member pathways
8.5CDKN2A, PCNA, TP53
158.5CDKN2A, PCNA, TP53
16
Show member pathways
8.5CDKN2A, PCNA, TP53
178.5CDKN2A, PCNA, TP53
18
Show member pathways
8.5CDKN2A, PCNA, TP53

GO Terms for genes affiliated with Bizarre Leiomyoma

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Biological processes related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell cycle arrestGO:00070509.5CDKN2A, TP53
2nucleotide-excision repairGO:00062899.2PCNA, TP53
3negative regulation of cell growthGO:00303089.1CDKN2A, TP53
4replicative senescenceGO:00903999.0CDKN2A, TP53
5protein sumoylationGO:00169258.8CDKN2A, PCNA, TP53
6apoptotic processGO:00069158.3ACTC1, CDKN2A, TP53

Sources for Bizarre Leiomyoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet