MCID: BZR001
MIFTS: 32

Bizarre Leiomyoma malady

Category: Cancer diseases

Aliases & Classifications for Bizarre Leiomyoma

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Aliases & Descriptions for Bizarre Leiomyoma:

Name: Bizarre Leiomyoma 11 13 66
Pleomorphic Leiomyoma 11
 
Symplastic Leiomyoma 11
Atypical Leiomyoma 11

Classifications:



External Ids:

Disease Ontology11 DOID:5127
SNOMED-CT60 48897006
NCIt43 C4257

Summaries for Bizarre Leiomyoma

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MalaCards based summary: Bizarre Leiomyoma, also known as pleomorphic leiomyoma, is related to leiomyosarcoma and uterine corpus bizarre leiomyoma. An important gene associated with Bizarre Leiomyoma is PGR (Progesterone Receptor), and among its related pathways are DNA damage_ATM/ATR regulation of G1/S checkpoint and BARD1 signaling events. Affiliated tissues include prostate, uterus and smooth muscle, and related mouse phenotypes are no phenotypic analysis and cardiovascular system.

Related Diseases for Bizarre Leiomyoma

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Diseases related to Bizarre Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 160)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyosarcoma30.6PGR, TP53
2uterine corpus bizarre leiomyoma12.2
3leiomyoma10.6
4ovarian cystadenocarcinoma10.5ACTC1, PCNA
5mushroom workers' lung10.5ACTC1, TP53
6mollaret meningitis10.4ACTC1, PGR
7eccrine papillary adenoma10.4ACTC1, TP53
8skin glomangioma10.4ACTC1, TP53
9parachordoma10.4ACTC1, PGR
10postcricoid region cancer10.4ACTC1, PGR
11paranasal sinus cancer, adult10.4ACTC1, TP53
12lymphocytic vasculitis10.4PCNA, PGR
13glioma susceptibility 110.4ACTC1, TP53
14pylorus cancer10.4PCNA, TP53
15mediastinum teratoma10.4PCNA, TP53
16localized epiphyseal dysplasia10.4ACTC1, TP53
17multidrug-resistant tuberculosis10.4PCNA, TP53
18lipoatrophy with diabetes, leukomelanodermic papules, liver steatosis, and hypertrophic cardiomyopathy10.3ACTC1, PGR
19prolapse of lacrimal gland10.3PCNA, PGR
20mixed cell type kidney wilms' tumor10.3PGR, TP53
21frontal sinus inverted papilloma10.3PGR, TP53
22animal phobia10.3PGR, TP53
23ovarian brenner tumor10.3PGR, TP53
24uterine body mixed cancer10.3PGR, TP53
25central nervous system germinoma10.3PGR, TP53
26cholesteatoma of external ear10.3PGR, TP53
27vibratory urticaria10.3PGR, TP53
28ovarian small cell carcinoma10.3PGR, TP53
29distal monosomy 9p10.3PGR, TP53
30nerve fibre bundle defect10.3PGR, TP53
31epithelioid type angiomyolipoma10.3PGR, TP53
32gastrointestinal system cancer10.3PGR, TP53
33vulval paget's disease10.3PGR, TP53
34manouvrier syndrome10.2MED12, TP53
35papillary carcinoma10.2PGR, TP53
36mixed cerebral palsy10.2PGR, TP53
37dental caries10.2PGR, TP53
38neutrophil immunodeficiency syndrome10.2ACTC1, TP53
39ovarian wilms' cancer10.2PGR, TP53
40lung carcinoma in situ10.2PGR, TP53
41mixed extragonadal germ cell cancer10.2ACTC1, TP53
42vestibular gland benign neoplasm10.2PGR, TP53
43thoracic benign neoplasm10.2MED12, PGR
44gastrointestinal system benign neoplasm10.2MED12, PGR
45progesterone-receptor positive breast cancer10.2PGR, TP53
46kidney benign neoplasm10.2PGR, TP53
47vulvar leiomyoma10.2MED12, PGR
48lobular neoplasia10.2PGR, TP53
49pineal region meningioma10.2PGR, TP53
50retinal dystrophies primarily involving bruch's membrane10.2MED12, PGR

Graphical network of the top 20 diseases related to Bizarre Leiomyoma:



Diseases related to bizarre leiomyoma

Symptoms for Bizarre Leiomyoma

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Drugs & Therapeutics for Bizarre Leiomyoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Bizarre Leiomyoma

Genetic Tests for Bizarre Leiomyoma

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Anatomical Context for Bizarre Leiomyoma

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MalaCards organs/tissues related to Bizarre Leiomyoma:

34
Prostate, Uterus, Smooth muscle

Animal Models for Bizarre Leiomyoma or affiliated genes

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MGI Mouse Phenotypes related to Bizarre Leiomyoma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.3CDKN2A, PCNA, PGR, TP53
2MP:00053857.6ACTC1, CDKN2A, MED12, PGR, TP53
3MP:00107686.8ACTC1, CDKN2A, MED12, PCNA, PGR, TP53

Publications for Bizarre Leiomyoma

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Articles related to Bizarre Leiomyoma:

(show all 22)
idTitleAuthorsYear
1
Bizarre leiomyoma of uterus/smooth muscle tumor of uncertain malignant potential: A diagnostic dilemma. (26960523)
2015
2
Bizarre leiomyoma of the scrotum: A case report and review of the literature. (24765204)
2014
3
Successful pregnancy outcome after laparoscopic-assisted excision of a bizarre leiomyoma: a case report. (21812974)
2011
4
A rare symplastic or bizarre leiomyoma of the scrotum: a case report and review of the literature. (19068127)
2008
5
Bizarre leiomyoma of the posterior vaginal fornix. (18501906)
2008
6
Bizarre leiomyoma of the soft tissue. (16194835)
2005
7
Bizarre leiomyoma of scrotum. (16146275)
2005
8
Pathologic quiz case: a 69-year-old asymptomatic man with a scrotal mass. Atypical (symplastic or bizarre) leiomyoma of the scrotum. (14736263)
2004
9
Bizarre leiomyoma of the scrotum. (12808340)
2003
10
Atypical (bizarre) leiomyoma of the nasal cavity with prominent myxoid change. (12401830)
2002
11
A clinicopathological study of bizarre leiomyoma]. (12485480)
2002
12
Bizarre leiomyoma of the vagina: report of a case. (10782419)
2000
13
Bizarre leiomyoma of the epididymis. A case report. (11517827)
2000
14
Bizarre leiomyoma of the prostate. (9126110)
1997
15
Neoplastic association of leiomyoma, bizarre leiomyoma and leiomyosarcoma uteri. Case report. (7828608)
1994
16
Bizarre leiomyoma of the renal pelvis with ultrastructural and immunohistochemical findings. (2926892)
1989
17
Complex karyotypic anomalies in a bizarre leiomyoma of the uterus. (2487152)
1989
18
Bizarre leiomyoma of the prostate. (3125678)
1988
19
Uterine bizarre leiomyoma. (7113686)
1982
20
Bizarre leiomyoma of the stomach: Case report. (5266968)
1970
21
A comprative electron microscopic study of a leiomyosarcoma and bizarre leiomyoma (leiomyoblastoma) of the stomach. (5820970)
1969
22
Bizarre leiomyoma (leiomyoblastoma). Report of a case. (14009016)
1962

Variations for Bizarre Leiomyoma

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Expression for genes affiliated with Bizarre Leiomyoma

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Search GEO for disease gene expression data for Bizarre Leiomyoma.

Pathways for genes affiliated with Bizarre Leiomyoma

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GO Terms for genes affiliated with Bizarre Leiomyoma

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Biological processes related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestGO:00069779.6PCNA, TP53
2cellular response to UVGO:00346449.5PCNA, TP53
3replicative senescenceGO:00903999.3CDKN2A, TP53
4Ras protein signal transductionGO:00072659.1CDKN2A, TP53

Molecular functions related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1histone acetyltransferase bindingGO:00350359.9PCNA, TP53
2damaged DNA bindingGO:00036849.8PCNA, TP53
3receptor tyrosine kinase bindingGO:00309719.5PCNA, TP53
4chromatin bindingGO:00036828.8MED12, PCNA, TP53
5enzyme bindingGO:00198998.7PCNA, PGR, TP53

Sources for Bizarre Leiomyoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet