Bizarre Leiomyoma disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Bizarre Leiomyoma

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³²MalaCards
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MalaCards: Bizarre Leiomyoma, also known as pleomorphic leiomyoma, is related to leiomyoma and leiomyosarcoma. An important gene associated with Bizarre Leiomyoma is ACTC1 (actin, alpha, cardiac muscle 1). The compounds reticulin and b 723 have been mentioned in the context of this disorder. Affiliated tissues include uterus and prostate.

Aliases & Classifications for Bizarre Leiomyoma

Sources:
⁸Disease Ontology, ⁶⁰UMLS, ³⁹NCIt, ⁵⁶SNOMED-CT
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Aliases & Descriptions:

bizarre leiomyoma ⁸ ⁶⁰

pleomorphic leiomyoma ⁸

symplastic leiomyoma ⁸

atypical leiomyoma ⁸

External Ids:

Disease Ontology⁸ DOID:5127

SNOMED-CT⁵⁶ 48897006

NCIt³⁹ C4257

UMLS⁶⁰ C0334478

Related Diseases for Bizarre Leiomyoma

Sources:
¹⁷GeneCards, ¹⁸GeneDecks
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Diseases related to Bizarre Leiomyoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 28)

id	Related Disease	Score	Top Affiliating Genes
1	leiomyoma	31.1	PCNA, ACTC1
2	leiomyosarcoma	30.4	ACTC1
3	smooth muscle tumor	29.9	ACTC1, PCNA
4	uterine corpus bizarre leiomyoma	10.4
5	prostate leiomyoma	10.3
6	prostatitis	10.3
7	vagina leiomyoma	10.1
8	vaginitis	10.1
9	bladder leiomyoma	10.0
10	uterine inversion	10.0
11	oligodendroglioma	10.0	PCNA
12	myoepithelioma	10.0	ACTC1
13	desmoid tumor	10.0	ACTC1
14	meningioma	10.0	PCNA
15	fibromatosis	10.0	ACTC1
16	teratoma	10.0	ACTC1
17	wilms tumor	10.0	ACTC1
18	rhabdomyosarcoma	10.0	ACTC1
19	medulloblastoma	10.0	ACTC1
20	dilated cardiomyopathy	10.0	ACTC1
21	endometriosis	10.0	ACTC1
22	mucoepidermoid carcinoma	10.0	ACTC1, PCNA
23	pleomorphic adenoma	10.0	PCNA, ACTC1
24	adenoid cystic carcinoma	10.0	PCNA, ACTC1
25	gastrointestinal stromal tumor	10.0	PCNA, ACTC1
26	papilloma	10.0	ACTC1, PCNA
27	kidney cancer	10.0	PCNA, ACTC1
28	breast cancer	10.0	ACTC1, PCNA

Graphical network of the top 20 diseases related to Bizarre Leiomyoma:

Clinical Features for Bizarre Leiomyoma

Drugs & Therapeutics for Bizarre Leiomyoma

Sources:
⁵CenterWatch, ⁴¹NIH Clinical Center, ⁶ClinicalTrials
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Approved drugs:

Search CenterWatch for Bizarre Leiomyoma

Drug clinical trials:

Search ClinicalTrials for Bizarre Leiomyoma

Search NIH Clinical Center for Bizarre Leiomyoma

Search CenterWatch for Bizarre Leiomyoma

Genetic Tests for Bizarre Leiomyoma

Anatomical Context for Bizarre Leiomyoma

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³²MalaCards
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MalaCards organs/tissues related to Bizarre Leiomyoma:

³²

Uterus, Prostate

Animal Models for Bizarre Leiomyoma or affiliated genes

Publications for Bizarre Leiomyoma

Sources:
⁵⁰PubMed
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Articles related to Bizarre Leiomyoma:

(show all 22)

id	Title	Authors	Year
1	Removal of a large bizarre uterine leiomyoma by operative hysteroscopy. Case report and review of the literature. (22675972)	Gregoriou O.... Kondi-Pafiti A.	2012
2	Successful pregnancy outcome after laparoscopic-assisted excision of a bizarre leiomyoma: a case report. (21812974)	Takeda A.... Nakamura H.	2011
3	Bizarre leiomyoma of the posterior vaginal fornix. (18501906)	Vlahos N.... Moraitis D.	2008
4	A rare symplastic or bizarre leiomyoma of the scrotum: a case report and review of the literature. (19068127)	Masood J.... Carr T.W.	2008
5	Bizarre leiomyoma of scrotum. (16146275)	Celia A.... Bianchi G.	2005
6	Bizarre leiomyoma of the soft tissue. (16194835)	Son H.J.... Moon W.S.	2005
7	Pathologic quiz case: a 69-year-old asymptomatic man with a scrotal mass. Atypical (symplastic or bizarre) leiomyoma of the scrotum. (14736263)	Fadare O.... Mariappan M.R.	2004
8	Bizarre leiomyoma of the scrotum. (12808340)	Kim N.R.... Han J.	2003
9	Atypical (bizarre) leiomyoma of the nasal cavity with prominent myxoid change. (12401830)	Vincenzi A.... Rivasi F.	2002
10	A clinicopathological study of bizarre leiomyoma]. (12485480)	Li B.... Wang D.	2002
11	Bizarre leiomyoma of the epididymis. A case report. (11517827)	Borri A.... Pernice L.M.	2000
12	Bizarre leiomyoma of the vagina: report of a case. (10782419)	Biankin S.A.... Russell P.	2000
13	Bizarre leiomyoma of the prostate. (9126110)	Khalil K.H.... al-Rufaie H.K.	1997
14	Leiomyosarcoma versus bizarre and cellular leiomyomas of the uterus: a comparative study based on the MIB-1 and proliferating cell nuclear antigen indices, p53 expression, DNA flow cytometry, and muscle specific actins. (8601525)	Amada S.... Tsuneyoshi M.	1995
15	Neoplastic association of leiomyoma, bizarre leiomyoma and leiomyosarcoma uteri. Case report. (7828608)	Tartagni M.... Loizzi P.	1994
16	Bizarre leiomyoma of the renal pelvis with ultrastructural and immunohistochemical findings. (2926892)	Kho G.T.... Duggan M.A.	1989
17	Complex karyotypic anomalies in a bizarre leiomyoma of the uterus. (2487152)	Nilbert M.... Mitelman F.	1989
18	Bizarre leiomyoma of the prostate. (3125678)	KA!rolyi P.... TAPnkAPl I.	1988
19	Uterine bizarre leiomyoma. (7113686)	KlA1nder K.B.... ller P.C.	1982
20	Bizarre leiomyoma of the stomach: Case report. (5266968)	Xipell J.M.	1970
21	A comprative electron microscopic study of a leiomyosarcoma and bizarre leiomyoma (leiomyoblastoma) of the stomach. (5820970)	Kay S.... STILL W.J.	1969
22	Bizarre leiomyoma (leiomyoblastoma). Report of a case. (14009016)	Yarington C.T.... Cook M.D.	1962

Genes related to Bizarre Leiomyoma

Sources:
¹⁷GeneCards, ⁴⁵Novus Biologicals, ³¹LifeSpan BioSciences, Inc.
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Genes related to Bizarre Leiomyoma:

id	Symbol	Products	Description	Score	Implication
1	ACTC1		actin, alpha, cardiac muscle 1	25.16	GeneCards inferred : Publications, Disorders (show sections)
2	PCNA		proliferating cell nuclear antigen	15.16	GeneCards inferred : Publications, Disorders (show sections)

Products for genes related to Bizarre Leiomyoma disease:

id	Company	Proteins	Lysates	Antibodies
1	Novus Biologicals	2	2	2
2	LSBio	-	-	2

Genetic Variations for Bizarre Leiomyoma

Expression for genes affiliated with Bizarre Leiomyoma

Sources:
¹BioGPS, ¹⁵Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bizarre Leiomyoma

Search GEO for disease gene expression data for Bizarre Leiomyoma.

Pathways for genes affiliated with Bizarre Leiomyoma

Compounds for genes affiliated with Bizarre Leiomyoma

Sources:
⁴⁴Novoseek, ¹¹DrugBank, ²⁴HMDB, ²⁸IUPHAR, ⁵⁹Tocris Bioscience
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Compounds related to Bizarre Leiomyoma according to GeneCards/GeneDecks:

(show all 11)

id	Compound	Score	Top Affiliating Genes
1	reticulin⁴⁴	9.4	PCNA, ACTC1
2	b 723⁴⁴	9.4	PCNA, ACTC1
3	hematoxylin⁴⁴	9.3	PCNA, ACTC1
4	procollagen⁴⁴	9.3	PCNA, ACTC1
5	biotin⁴⁴ ¹¹ ²⁴	11.3	PCNA, ACTC1
6	formaldehyde⁴⁴ ²⁴	10.2	ACTC1, PCNA
7	paraffin⁴⁴	9.2	PCNA, ACTC1
8	cyclosporin a⁴⁴ ²⁸ ⁵⁹	11.1	ACTC1, PCNA
9	testosterone⁴⁴ ⁵⁹ ¹¹ ²⁴	12.1	PCNA, ACTC1
10	creatinine⁴⁴	9.0	PCNA, ACTC1
11	progesterone⁴⁴ ⁵⁹ ²⁸ ¹¹ ²⁴	12.8	PCNA, ACTC1