MCID: BZR001
MIFTS: 34

Bizarre Leiomyoma malady

Category: Cancer diseases

Aliases & Classifications for Bizarre Leiomyoma

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Aliases & Descriptions for Bizarre Leiomyoma:

Name: Bizarre Leiomyoma 10 12 65
Pleomorphic Leiomyoma 10
 
Symplastic Leiomyoma 10
Atypical Leiomyoma 10

Classifications:



External Ids:

Disease Ontology10 DOID:5127
SNOMED-CT59 48897006
NCIt42 C4257
UMLS65 C0334478

Summaries for Bizarre Leiomyoma

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MalaCards based summary: Bizarre Leiomyoma, also known as pleomorphic leiomyoma, is related to uterine corpus bizarre leiomyoma and leiomyoma. An important gene associated with Bizarre Leiomyoma is ACTC1 (Actin, Alpha, Cardiac Muscle 1), and among its related pathways are BARD1 signaling events and GADD45 Pathway. Affiliated tissues include breast, prostate and ovary, and related mouse phenotypes are muscle and no phenotypic analysis.

Related Diseases for Bizarre Leiomyoma

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Diseases related to Bizarre Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1uterine corpus bizarre leiomyoma12.2
2leiomyoma10.6
3benign multicystic peritoneal mesothelioma10.4ACTC1, PGR
4adult mesoblastic nephroma10.4ACTC1, PGR
5ovarian mucinous cystadenocarcinoma10.4ACTC1, PCNA
6thymus lipoma10.4ACTC1, PGR
7oral tuberculosis10.3ACTC1, PGR
8pyridoxal 5'-phosphate-dependent epilepsy10.3ACTC1, TP53
9secretory meningioma10.3PCNA, PGR
10prostatic cyst10.3PCNA, PGR
11pulmonary immaturity10.3ACTC1, TP53
12syringocystadenoma papilliferum10.3ACTC1, TP53
13cervical adenoid cystic carcinoma10.3PCNA, PGR
14small intestine leiomyosarcoma10.3ACTC1, TP53
15proliferative fasciitis10.3ACTC1, TP53
16metachronous kidney wilms' tumor10.2PGR, TP53
17ovary neuroendocrine neoplasm10.2PGR, TP53
18hypothyroidism due to deficient transcription factors involved in pituitary development or function10.2ACTC1, TP53
19ovarian mesodermal adenosarcoma10.2PGR, TP53
20pituitary stalk meningioma10.2PGR, TP53
21cystadenoma10.2PGR, TP53
22uterine corpus adenosarcoma10.2PGR, TP53
23corneal neovascularization10.2PGR, TP53
24pyelonephritis10.2PGR, TP53
25exposure keratitis10.2PGR, TP53
26skull base meningioma10.2PGR, TP53
27internal auditory canal lipoma10.2PGR, TP53
28immune system cancer10.2PGR, TP53
29osteoblastoma10.2PGR, TP53
30head and neck carcinoma10.2PGR, TP53
31peritoneal cystic mesothelioma10.2PGR, TP53
32fallopian tube leiomyosarcoma10.2PGR, TP53
33uterine carcinosarcoma10.2PGR, TP53
34eye carcinoma in situ10.2PGR, TP53
35vulvar sarcoma10.2PGR, TP53
363-methylglutaconic aciduria, type i10.2PCNA, TP53
37dyskinetic cerebral palsy10.1PGR, TP53
38male reproductive organ benign neoplasm10.1PGR, TP53
39ovary epithelial cancer10.1PGR, TP53
40ovarian wilms' cancer10.1PGR, TP53
41embryonal carcinoma10.1ACTC1, TP53
42cervical endometrial stromal sarcoma10.1ACTC1, TP53
43bone ameloblastoma10.1PCNA, TP53
44malignant epithelial mesothelioma10.1ACTC1, CDKN2A
45estrogen-receptor negative breast cancer10.1PGR, TP53
46benign mesothelioma10.1ACTC1, CDKN2A
47larynx sarcoma10.1PGR, TP53
48periocular meningioma10.1PGR, TP53
49prostatitis10.1
50leiomyosarcoma10.1

Graphical network of the top 20 diseases related to Bizarre Leiomyoma:



Diseases related to bizarre leiomyoma

Symptoms for Bizarre Leiomyoma

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Drugs & Therapeutics for Bizarre Leiomyoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Bizarre Leiomyoma

Genetic Tests for Bizarre Leiomyoma

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Anatomical Context for Bizarre Leiomyoma

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MalaCards organs/tissues related to Bizarre Leiomyoma:

33
Breast, Prostate, Ovary, Pituitary, Colon, Uterus, Monocytes

Animal Models for Bizarre Leiomyoma or affiliated genes

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MGI Mouse Phenotypes related to Bizarre Leiomyoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.1ACTC1, CDKN2A, PGR, TP53
2MP:00030127.7CDKN2A, PCNA, PGR, TP53

Publications for Bizarre Leiomyoma

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Articles related to Bizarre Leiomyoma:

(show all 22)
idTitleAuthorsYear
1
Bizarre leiomyoma of uterus/smooth muscle tumor of uncertain malignant potential: A diagnostic dilemma. (26960523)
2015
2
Bizarre leiomyoma of the scrotum: A case report and review of the literature. (24765204)
2014
3
Successful pregnancy outcome after laparoscopic-assisted excision of a bizarre leiomyoma: a case report. (21812974)
2011
4
Bizarre leiomyoma of the posterior vaginal fornix. (18501906)
2008
5
A rare symplastic or bizarre leiomyoma of the scrotum: a case report and review of the literature. (19068127)
2008
6
Bizarre leiomyoma of scrotum. (16146275)
2005
7
Bizarre leiomyoma of the soft tissue. (16194835)
2005
8
Pathologic quiz case: a 69-year-old asymptomatic man with a scrotal mass. Atypical (symplastic or bizarre) leiomyoma of the scrotum. (14736263)
2004
9
Bizarre leiomyoma of the scrotum. (12808340)
2003
10
Atypical (bizarre) leiomyoma of the nasal cavity with prominent myxoid change. (12401830)
2002
11
A clinicopathological study of bizarre leiomyoma]. (12485480)
2002
12
Bizarre leiomyoma of the epididymis. A case report. (11517827)
2000
13
Bizarre leiomyoma of the vagina: report of a case. (10782419)
2000
14
Bizarre leiomyoma of the prostate. (9126110)
1997
15
Neoplastic association of leiomyoma, bizarre leiomyoma and leiomyosarcoma uteri. Case report. (7828608)
1994
16
Bizarre leiomyoma of the renal pelvis with ultrastructural and immunohistochemical findings. (2926892)
1989
17
Complex karyotypic anomalies in a bizarre leiomyoma of the uterus. (2487152)
1989
18
Bizarre leiomyoma of the prostate. (3125678)
1988
19
Uterine bizarre leiomyoma. (7113686)
1982
20
Bizarre leiomyoma of the stomach: Case report. (5266968)
1970
21
A comprative electron microscopic study of a leiomyosarcoma and bizarre leiomyoma (leiomyoblastoma) of the stomach. (5820970)
1969
22
Bizarre leiomyoma (leiomyoblastoma). Report of a case. (14009016)
1962

Variations for Bizarre Leiomyoma

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Expression for genes affiliated with Bizarre Leiomyoma

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Search GEO for disease gene expression data for Bizarre Leiomyoma.

Pathways for genes affiliated with Bizarre Leiomyoma

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Pathways related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
19.3PCNA, TP53
29.3PCNA, TP53
39.3PCNA, TP53
49.3PCNA, TP53
59.3PCNA, TP53
69.0CDKN2A, TP53
7
Show member pathways
9.0CDKN2A, TP53
89.0CDKN2A, TP53
99.0CDKN2A, TP53
109.0CDKN2A, TP53
11
Show member pathways
9.0CDKN2A, TP53
129.0CDKN2A, TP53
138.5CDKN2A, PCNA, TP53
14
Show member pathways
8.5CDKN2A, PCNA, TP53
158.5CDKN2A, PCNA, TP53
16
Show member pathways
8.5CDKN2A, PCNA, TP53
178.5CDKN2A, PCNA, TP53
18
Show member pathways
8.5CDKN2A, PCNA, TP53

GO Terms for genes affiliated with Bizarre Leiomyoma

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Biological processes related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell cycle arrestGO:00070509.5CDKN2A, TP53
2nucleotide-excision repairGO:00062899.2PCNA, TP53
3negative regulation of cell growthGO:00303089.1CDKN2A, TP53
4replicative senescenceGO:00903999.0CDKN2A, TP53
5protein sumoylationGO:00169258.8CDKN2A, PCNA, TP53
6apoptotic processGO:00069158.3ACTC1, CDKN2A, TP53

Sources for Bizarre Leiomyoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet