MCID: BZR001
MIFTS: 31

Bizarre Leiomyoma malady

Categories: Cancer diseases

Aliases & Classifications for Bizarre Leiomyoma

Aliases & Descriptions for Bizarre Leiomyoma:

Name: Bizarre Leiomyoma 12 14 69
Pleomorphic Leiomyoma 12
Symplastic Leiomyoma 12
Atypical Leiomyoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5127
NCIt 47 C4257
SNOMED-CT 64 48897006
UMLS 69 C0334478

Summaries for Bizarre Leiomyoma

MalaCards based summary : Bizarre Leiomyoma, also known as pleomorphic leiomyoma, is related to uterine corpus bizarre leiomyoma and leiomyoma. An important gene associated with Bizarre Leiomyoma is PGR (Progesterone Receptor), and among its related pathways/superpathways are Gene Expression and SUMOylation. Affiliated tissues include prostate, uterus and smooth muscle, and related phenotypes are cardiovascular system and mortality/aging

Related Diseases for Bizarre Leiomyoma

Diseases related to Bizarre Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)
id Related Disease Score Top Affiliating Genes
1 uterine corpus bizarre leiomyoma 12.1
2 leiomyoma 10.5
3 hydrarthrosis 10.2 ACTC1 PGR
4 biemond syndrome 10.2 ACTC1 PGR
5 sebaceous adenoma 10.2 ACTC1 PGR
6 lymphomatous thyroiditis 10.2 PCNA PGR
7 pleuropneumonia 10.2 CDKN2A PGR
8 perinatal necrotizing enterocolitis 10.2 ACTC1 PGR
9 bladder adenocarcinoma 10.2 CDKN2A PGR
10 anal neuroendocrine tumor 10.2 CDKN2A PGR
11 pilar sheath acanthoma 10.2 ACTC1 PGR
12 vulva basal cell carcinoma 10.2 CDKN2A PGR
13 13q12.3 microdeletion syndrome 10.2 ACTC1 CDKN2A
14 fitz-hugh-curtis syndrome 10.2 ACTC1 PGR
15 common bile duct neoplasm 10.2 PCNA PGR
16 vulvar alveolar soft part sarcoma 10.2 CDKN2A PGR
17 episodic ataxia 10.2 ACTC1 CDKN2A
18 mediastinum liposarcoma 10.2 ACTC1 CDKN2A
19 gangliosidosis gm1 10.2 ACTC1 PGR
20 scirrhous adenocarcinoma 10.2 ACTC1 PGR
21 deafness, autosomal recessive 74 10.1 MED12 PGR
22 osteoblastoma 10.1 MED12 PGR
23 biliary tract neoplasm 10.1 MED12 PGR
24 epithelioid neurofibroma 10.1 MED12 PGR
25 haverhill fever 10.1 MED12 PGR
26 caroli disease 10.1 ACTC1 CDKN2A
27 breast duct papilloma 10.1 MED12 PGR
28 aortitis 10.1 PGR TP53
29 breast ductal carcinoma 10.1 PGR TP53
30 acinar cell carcinoma 10.1 PGR TP53
31 classic congenital mesoblastic nephroma 10.1 PGR TP53
32 porokeratosis 10.1 PGR TP53
33 breast pericanalicular fibroadenoma 10.1 PGR TP53
34 villoglandular endometrial endometrioid adenocarcinoma 10.1 PGR TP53
35 vaginal adenosarcoma 10.1 PGR TP53
36 central nervous system mature teratoma 10.1 PGR TP53
37 seminoma 10.1 PGR TP53
38 ovarian embryonal carcinoma 10.1 PGR TP53
39 postpartum depression 10.1 PGR TP53
40 hemangioma of liver 10.1 ACTC1 TP53
41 conjunctival cancer 10.1 ACTC1 TP53
42 reactive arthritis 10.1 PGR TP53
43 coronary stenosis 10.1 ACTC1 TP53
44 arthus reaction 10.1 PGR TP53
45 fallopian tube carcinosarcoma 10.0 PGR TP53
46 glomangioma 10.0 ACTC1 TP53
47 clear cell adenofibroma 10.0 CDKN2A TP53
48 lacrimal gland adenoid cystic carcinoma 10.0 CDKN2A TP53
49 immunodeficiency due to a late component of complement deficiency 10.0 PGR TP53
50 spondylarthropathy 10.0 CDKN2A TP53

Graphical network of the top 20 diseases related to Bizarre Leiomyoma:



Diseases related to Bizarre Leiomyoma

Symptoms & Phenotypes for Bizarre Leiomyoma

MGI Mouse Phenotypes related to Bizarre Leiomyoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.55 ACTC1 CDKN2A MED12 PGR TP53
2 mortality/aging MP:0010768 9.43 ACTC1 CDKN2A MED12 PCNA PGR TP53
3 no phenotypic analysis MP:0003012 8.92 CDKN2A PCNA PGR TP53

Drugs & Therapeutics for Bizarre Leiomyoma

Search Clinical Trials , NIH Clinical Center for Bizarre Leiomyoma

Genetic Tests for Bizarre Leiomyoma

Anatomical Context for Bizarre Leiomyoma

MalaCards organs/tissues related to Bizarre Leiomyoma:

39
Prostate, Uterus, Smooth Muscle

Publications for Bizarre Leiomyoma

Articles related to Bizarre Leiomyoma:

(show all 22)
id Title Authors Year
1
Bizarre leiomyoma of uterus/smooth muscle tumor of uncertain malignant potential: A diagnostic dilemma. ( 26960523 )
2015
2
Bizarre leiomyoma of the scrotum: A case report and review of the literature. ( 24765204 )
2014
3
Successful pregnancy outcome after laparoscopic-assisted excision of a bizarre leiomyoma: a case report. ( 21812974 )
2011
4
Bizarre leiomyoma of the posterior vaginal fornix. ( 18501906 )
2008
5
A rare symplastic or bizarre leiomyoma of the scrotum: a case report and review of the literature. ( 19068127 )
2008
6
Bizarre leiomyoma of scrotum. ( 16146275 )
2005
7
Bizarre leiomyoma of the soft tissue. ( 16194835 )
2005
8
Pathologic quiz case: a 69-year-old asymptomatic man with a scrotal mass. Atypical (symplastic or bizarre) leiomyoma of the scrotum. ( 14736263 )
2004
9
Bizarre leiomyoma of the scrotum. ( 12808340 )
2003
10
[A clinicopathological study of bizarre leiomyoma]. ( 12485480 )
2002
11
Atypical (bizarre) leiomyoma of the nasal cavity with prominent myxoid change. ( 12401830 )
2002
12
Bizarre leiomyoma of the vagina: report of a case. ( 10782419 )
2000
13
Bizarre leiomyoma of the epididymis. A case report. ( 11517827 )
2000
14
Bizarre leiomyoma of the prostate. ( 9126110 )
1997
15
Neoplastic association of leiomyoma, bizarre leiomyoma and leiomyosarcoma uteri. Case report. ( 7828608 )
1994
16
Bizarre leiomyoma of the renal pelvis with ultrastructural and immunohistochemical findings. ( 2926892 )
1989
17
Complex karyotypic anomalies in a bizarre leiomyoma of the uterus. ( 2487152 )
1989
18
Bizarre leiomyoma of the prostate. ( 3125678 )
1988
19
Uterine bizarre leiomyoma. ( 7113686 )
1982
20
Bizarre leiomyoma of the stomach: Case report. ( 5266968 )
1970
21
A comprative electron microscopic study of a leiomyosarcoma and bizarre leiomyoma (leiomyoblastoma) of the stomach. ( 5820970 )
1969
22
Bizarre leiomyoma (leiomyoblastoma). Report of a case. ( 14009016 )
1962

Variations for Bizarre Leiomyoma

Expression for Bizarre Leiomyoma

Search GEO for disease gene expression data for Bizarre Leiomyoma.

Pathways for Bizarre Leiomyoma

Pathways related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

(show all 19)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.39 CDKN2A MED12 PCNA PGR TP53
2
Show member pathways
12.23 CDKN2A PCNA TP53
3
Show member pathways
12.2 CDKN2A PCNA TP53
4 12.12 CDKN2A PCNA TP53
5 11.99 CDKN2A PCNA TP53
6 11.86 CDKN2A PCNA TP53
7 11.45 CDKN2A TP53
8 11.44 CDKN2A TP53
9
Show member pathways
11.43 CDKN2A TP53
10 11.28 CDKN2A TP53
11 11.26 CDKN2A PCNA TP53
12 11.24 CDKN2A TP53
13 11.14 PCNA TP53
14 10.96 PCNA TP53
15 10.94 CDKN2A TP53
16 10.83 PCNA TP53
17 10.82 CDKN2A PCNA TP53
18 10.6 CDKN2A TP53
19
Show member pathways
10.5 CDKN2A TP53

GO Terms for Bizarre Leiomyoma

Cellular components related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 replication fork GO:0005657 8.62 PCNA TP53

Biological processes related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 Ras protein signal transduction GO:0007265 9.32 CDKN2A TP53
2 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9.26 PCNA TP53
3 positive regulation of transcription from RNA polymerase II promoter GO:0045944 9.26 CDKN2A MED12 PGR TP53
4 cellular response to UV GO:0034644 9.16 PCNA TP53
5 replicative senescence GO:0090399 8.62 CDKN2A TP53

Molecular functions related to Bizarre Leiomyoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.54 MED12 PCNA TP53
2 enzyme binding GO:0019899 9.43 PCNA PGR TP53
3 damaged DNA binding GO:0003684 9.32 PCNA TP53
4 receptor tyrosine kinase binding GO:0030971 9.16 PCNA TP53
5 transcription factor binding GO:0008134 9.13 CDKN2A MED12 TP53
6 histone acetyltransferase binding GO:0035035 8.62 PCNA TP53

Sources for Bizarre Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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