Bladder Cancer, Somatic malady
Categories: Genetic diseases (common), Cancer diseases, Nephrological diseases
Aliases & Descriptions for Bladder Cancer, Somatic:
bladder cancer, somatic:
Inheritance: autosomal dominant inheritance
Global: Genetic diseases (common), Cancer diseases
Anatomical: Nephrological diseases
MedlinePlus:36 The bladder is a hollow organ in your lower abdomen that stores urine. bladder cancer occurs in the lining of the bladder. it is the sixth most common type of cancer in the united states. symptoms include blood in your urine a frequent urge to urinate pain when you urinate low back pain risk factors for developing bladder cancer include smoking and exposure to certain chemicals in the workplace. people with a family history of bladder cancer or who are older, white, or male have a higher risk. treatments for bladder cancer include surgery, radiation therapy, chemotherapy, and biologic therapy. biologic therapy boosts your body's own ability to fight cancer. nih: national cancer institute
MalaCards based summary: Bladder Cancer, Somatic, also known as bladder carcinoma, is related to papilloma and prostate cancer, and has symptoms including transitional cell carcinoma of the bladder An important gene associated with Bladder Cancer, Somatic is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways are Transcriptional activation of p53 responsive genes and MNAR-PELP1 and Estrogen Receptor Interaction. Affiliated tissues include testes, and related mouse phenotypes are hearing/vestibular/ear and craniofacial.
Disease Ontology:11 A urinary bladder cancer that has material basis in abnormally proliferating cells derives from epithelial cells.
UniProtKB/Swiss-Prot:68 Bladder cancer: A malignancy originating in tissues of the urinary bladder. It often presents with multiple tumors appearing at different times and at different sites in the bladder. Most bladder cancers are transitional cell carcinomas that begin in cells that normally make up the inner lining of the bladder. Other types of bladder cancer include squamous cell carcinoma (cancer that begins in thin, flat cells) and adenocarcinoma (cancer that begins in cells that make and release mucus and other fluids). Bladder cancer is a complex disorder with both genetic and environmental influences.
Genetics Home Reference:24 Bladder cancer is a disease in which certain cells in the bladder become abnormal and multiply without control or order. The bladder is a hollow, muscular organ in the lower abdomen that stores urine until it is ready to be excreted from the body. The most common type of bladder cancer begins in cells lining the inside of the bladder and is called transitional cell carcinoma (TCC).
Description from OMIM:50 109800
FDA approved drugs:
Drugs for Bladder Cancer, Somatic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
Interventional clinical trials:
Search NIH Clinical Center for Bladder Cancer, Somatic
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Bladder Cancer, Somatic cell therapies at LifeMap Discovery.
MalaCards organs/tissues related to Bladder Cancer, Somatic:34
MGI Mouse Phenotypes related to Bladder Cancer, Somatic:39 (show all 27)
UniProtKB/Swiss-Prot genetic disease variations for Bladder Cancer, Somatic:68
Clinvar genetic disease variations for Bladder Cancer, Somatic:5
Cosmic variations for Bladder Cancer, Somatic:8 (show all 47)
Copy number variations for Bladder Cancer, Somatic from CNVD:6 (show top 50) (show all 98)
Search GEO for disease gene expression data for Bladder Cancer, Somatic.
Pathways related to Bladder Cancer, Somatic according to GeneCards Suite gene sharing:(show top 50) (show all 61)
Cellular components related to Bladder Cancer, Somatic according to GeneCards Suite gene sharing:
Biological processes related to Bladder Cancer, Somatic according to GeneCards Suite gene sharing:(show all 20)
Molecular functions related to Bladder Cancer, Somatic according to GeneCards Suite gene sharing:
29ICD10 via Orphanet
38MESH via Orphanet
51OMIM via Orphanet
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
67UMLS via Orphanet