MCID: BLD044
MIFTS: 54

Bladder Disease malady

Nephrological diseases category
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Summaries for Bladder Disease

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MedlinePlus:33 The bladder is a hollow organ in your lower abdomen that stores urine. many conditions can affect your bladder. some common ones are cystitis - inflammation of the bladder, often from an infection urinary incontinence - loss of bladder control overactive bladder - a condition in which the bladder squeezes urine out at the wrong time interstitial cystitis - a chronic problem that causes bladder pain and frequent, urgent urination bladder cancer doctors diagnose bladder diseases using different tests. these include urine tests, x-rays, and an examination of the bladder wall with a scope called a cystoscope. treatment depends on the cause of the problem. it may include medicines and, in severe cases, surgery. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary: Bladder Disease, also known as bladder diseases, is related to cystitis and pancreatic cancer. An important gene associated with Bladder Disease is CCK (cholecystokinin), and among its related pathways are Transcription Androgen Receptor nuclear signaling and Cell adhesion ECM remodeling. The drugs acetic acid and neostigmine and the compounds dtpa and l-nmma have been mentioned in the context of this disorder. Affiliated tissues include testes, kidney and heart, and related mouse phenotype homeostasis/metabolism.

Wikipedia:65 Urinary bladder disease can be congenital or acquired. more...

Aliases & Classifications for Bladder Disease

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Bladder Disease, Aliases & Descriptions:

Name: Bladder Disease 30 8
Bladder Diseases 44 33
 
Urinary Bladder Diseases 62
Urinary Bladder Disease 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


External Ids:

Disease Ontology8 DOID:365
ICD9CM27 596.9
MeSH34 D001745
NCIt39 C2900

Related Diseases for Bladder Disease

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Graphical network of the top 20 diseases related to Bladder Disease:



Diseases related to bladder disease

Symptoms for Bladder Disease

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Drugs & Therapeutics for Bladder Disease

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Drug clinical trials:

Search ClinicalTrials for Bladder Disease

Search NIH Clinical Center for Bladder Disease

Inferred drug relations via UMLS62/NDF-RT40:

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Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Bladder Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Bladder Disease:
Neo-Urinary Conduit
Embryonic/Adult Cultured Cells Related to Bladder Disease:
Neo-Urinary Conduit, PMID: 22136657

Genetic Tests for Bladder Disease

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Anatomical Context for Bladder Disease

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MalaCards organs/tissues related to Bladder Disease:

32
Testes, Kidney, Heart, Prostate, Smooth muscle, Liver, Appendix

Animal Models for Bladder Disease or affiliated genes

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MGI Mouse Phenotypes related to Bladder Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.6TRPV1, CCK, CHRM3, HBEGF, IDO1

Publications for Bladder Disease

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Articles related to Bladder Disease:

(show top 50)    (show all 156)
idTitleAuthorsYear
1
Remodeling of the muscle layer (detrusor muscle) of hyperactive bladder disease in patients with benign prostatic hyperplasia. (23113284)
2012
2
Muscarinic acetylcholine receptor M3 mutation causes urinary bladder disease and a prune-belly-like syndrome. (22077972)
2011
3
The role of sodium hyaluronate and sodium chondroitin sulphate in the management of bladder disease. (22046200)
2011
4
A murine model of inflammatory bladder disease: cathelicidin peptide induced bladder inflammation and treatment with sulfated polysaccharides. (21855919)
2011
5
Overactive bladder disease: the urge for better therapies. (18500915)
2008
6
TRPs in bladder diseases. (17560087)
2007
7
EAU - 15th Congress. Urinary incontinence and bladder disease. (16080050)
2000
8
Long-term follow-up after clam ileocystoplasty. Complications and results including some quality-of-life parameters for 32 patients treated for neuropathic and nonneuropathic bladder disease. (8178380)
1994
9
Is gallbladder ejection fraction a reliable predictor of acalculous gall bladder disease? (8321495)
1993
10
Superficial bladder disease: case studies and therapeutic advances. (1466118)
1992
11
Gall bladder disease as seen in a Harare referral hospital centre. (2225019)
1990
12
Gall bladder disease: an analytical report of 250 cases. (2634700)
1989
13
Parathyroid hormone like bioactivity measured by cytochemical bioassay in a patient with malignant bladder disease. (3248932)
1988
14
A critical reappraisal of cystometry in neurogenic bladder diseases. (3686758)
1987
15
Urine eosinophil cationic protein in painful bladder disease. (3304514)
1987
16
Augmentation cystoplasty in the management of neurogenic bladder disease and urinary incontinence. (3959250)
1986
17
Imaging procedures to diagnose gall bladder disease. (6426669)
1984
18
Diagnosing gall bladder disease. (6428671)
1984
19
Significance of asymptomatic bacteriuria in neurogenic bladder disease. (6369712)
1984
20
The fatty meal and acalculous gall-bladder disease. (6467829)
1984
21
Risk factors for gall-bladder disease: a cohort study of young women attending family planning clinics. (7166683)
1982
22
HIDA scanning in gall-bladder disease. (7437710)
1980
23
Polycystic liver and other hepatic masses mimicking gall-bladder disease. (519149)
1979
24
The use of sacral nerve blocks in the evaluation and treatment of neurologic bladder disease. (904050)
1977
25
Classification of neurogenic bladder disease. (4428539)
1974
26
Gall bladder disease in childhood. (4642203)
1972
27
Gall bladder disease in children. (13978306)
1963
28
CHOLECYSTOGASTROSTOMY IN GALL BLADDER DISEASE. (14062626)
1963
29
Radiological diagnosis of gall bladder disease. (13946048)
1962
30
Myocardial infarction versus gall bladder disease. (13793640)
1960
31
The relationship between heart disease and gall-bladder disease. (13650430)
1959
32
Chronic gall bladder disease. (13584673)
1958
33
Gall bladder disease. (13184295)
1954
34
Practical management of gall bladder disease and its complications. (13149580)
1954
35
Diaphragmatic hernia associated with other gastro-intestinal and gall bladder disease. (18875479)
1948
36
Biliary stasis; the basis of most gall bladder disease. (18106386)
1948
37
On the so-called gall bladder disease. (20267322)
1947
38
Liver damage in gall bladder disease. (20258027)
1947
39
Diagnosis and medical management of gall bladder disease. (20259872)
1947
40
The medical treatment of gall bladder disease. (21001694)
1946
41
Early determination of gall bladder disease and its treatment. (21019023)
1946
42
The Clinical Pathology of Gall-Bladder Disease. (21313354)
1944
43
THE ASSOCIATION OF GALL-BLADDER DISEASE WITH CARDIAC LESIONS. (20320996)
1938
44
On the Mortality Resulting from Surgical Treatment of Chronic Gall-bladder Disease in Diabetes Mellitus. (17866803)
1932
45
OBSCURE GALL-BLADDER DISEASE. (18741249)
1929
46
Gassy Indigestion: Its Significance as a Symptom of Gall Bladder Disease, With a Review of Sixty Cases of Cholecystectomy. (20315666)
1926
47
THE MELTZER-LYONS TEST IN THE DIAGNOSIS OF GALL-BLADDER DISEASE. (17864926)
1923
48
GALL-BLADDER DISEASE IN CHILDHOOD. (17864826)
1923
49
IS THE MELTZER-LYON TECHNIC FOR THE DIAGNOSIS AND TREATMENT OF GALL BLADDER DISEASE AN ASSET OR A LIABILITY? (18738767)
1922
50
The Symptomatology of Gall-Bladder Disease. (18736005)
1913

Variations for Bladder Disease

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Expression for genes affiliated with Bladder Disease

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Expression patterns in normal tissues for genes affiliated with Bladder Disease

Search GEO for disease gene expression data for Bladder Disease.

Pathways for genes affiliated with Bladder Disease

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Compounds for genes affiliated with Bladder Disease

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Compounds related to Bladder Disease according to GeneCards/GeneDecks:

(show all 39)
idCompoundScoreTop Affiliating Genes
1dtpa449.9KLK3, CCK
2l-nmma449.9CCK, IDO1
34-diphenylacetoxy-n-methylpiperidine methiodide449.9CCK, CHRM3
4sulfate44 2410.9CCK, HBEGF
5bethanechol44 28 1111.9CCK, CHRM3
6cyproheptadine44 28 1111.8CHRM3, CCK
7pirenzepine44 28 1111.8CCK, CHRM3
8nicardipine44 28 1111.8CCK, CHRM3
9suramin44 28 1111.8KLK3, HBEGF
10atropine44 28 1111.8CHRM3, CCK
115-hydroxytryptamine449.8IDO1, CCK
12carbachol44 28 1111.7CCK, CHRM3
13aspartame44 24 1111.7CCK, TRPV1
14tetrodotoxin44 61 2811.6TRPV1, CCK
15inositol 1,4,5 trisphosphate449.6CCK, CHRM3
16amide449.6TRPV1, CCK
17menthol44 28 24 1112.5IDO1, TRPV1
18morphine44 50 28 1112.5TRPV1, CCK
19cgmp44 2810.5CHRM3, IDO1
20polysaccharide449.5HBEGF, CCK, KLK3
21phorbol 12,13-dibutyrate449.4TRPV1, CHRM3
22lidocaine44 28 1111.4CHRM3, TRPV1
23testosterone44 61 24 1112.4HBEGF, CCK, KLK3
24cycloheximide449.3KLK3, HBEGF, IDO1
25formaldehyde44 2410.3KLK3, TRPV1
26thapsigargin44 6110.2TRPV1, CCK
27inositol449.2TRPV1, CHRM3
28cyclosporin a44 28 6111.0TRPV1, CCK, CHRM3
29dexamethasone44 50 28 1112.0IDO1, HBEGF, CCK, KLK3
30adenylate449.0CHRM3, CCK, TRPV1
31nitric oxide44 24 1110.9IDO1, HBEGF, TRPV1
32oxygen44 249.7IDO1, HBEGF, TRPV1
33glucose448.7CCK, CHRM3, HBEGF
34pge2448.7TRPV1, CCK, HBEGF, IDO1
35glutamate448.7TRPV1, CCK, HBEGF, IDO1
36atp44 289.6TRPV1, CHRM3, HBEGF
37cysteine448.5HBEGF, CHRM3, TRPV1
38tyrosine448.1IDO1, HBEGF, CHRM3, CCK, TRPV1
39calcium44 50 24 1111.0IDO1, HBEGF, CHRM3, CCK, TRPV1

GO Terms for genes affiliated with Bladder Disease

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Cellular components related to Bladder Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1postsynaptic membraneGO:0452119.0TRPV1, CHRM3
2integral component of plasma membraneGO:0058878.3TRPV1, CHRM3, HBEGF

Biological processes related to Bladder Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1signal transductionGO:0071659.0CCK, CHRM3, HBEGF

Products for genes affiliated with Bladder Disease

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  • Antibodies
  • Proteins
  • Lysates

Sources for Bladder Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet