MCID: BLD044
MIFTS: 49

Bladder Disease malady

Nephrological diseases category

Aliases & Classifications for Bladder Disease

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Bladder Disease, Aliases & Descriptions:

Name: Bladder Disease 30 9
Bladder Diseases 43 32
 
Urinary Bladder Diseases 60
Urinary Bladder Disease 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


External Ids:

Disease Ontology9 DOID:365
MeSH33 D001745
ICD9CM27 596.9
NCIt38 C2900

Summaries for Bladder Disease

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MedlinePlus:32 The bladder is a hollow organ in your lower abdomen that stores urine. many conditions can affect your bladder. some common ones are cystitis - inflammation of the bladder, often from an infection urinary incontinence - loss of bladder control overactive bladder - a condition in which the bladder squeezes urine out at the wrong time interstitial cystitis - a chronic problem that causes bladder pain and frequent, urgent urination bladder cancer doctors diagnose bladder diseases using different tests. these include urine tests, x-rays, and an examination of the bladder wall with a scope called a cystoscope. treatment depends on the cause of the problem. it may include medicines and, in severe cases, surgery. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary: Bladder Disease, also known as bladder diseases, is related to cystitis and pancreatic cancer. An important gene associated with Bladder Disease is CCK (cholecystokinin), and among its related pathways are Transcription Androgen Receptor nuclear signaling and Cell adhesion ECM remodeling. The drugs acetic acid and neostigmine and the compounds dtpa and l-nmma have been mentioned in the context of this disorder. Affiliated tissues include the bladder, testes and kidney, and related mouse phenotype homeostasis/metabolism.

Disease Ontology:9 A urinary system disease that is located in the bladder.

Wikipedia:63 Urinary bladder disease includes urinary bladder inflammation such as cystitis, bladder rupture and... more...

Related Diseases for Bladder Disease

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Graphical network of the top 20 diseases related to Bladder Disease:



Diseases related to bladder disease

Symptoms for Bladder Disease

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Drugs & Therapeutics for Bladder Disease

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Drug clinical trials:

Search ClinicalTrials for Bladder Disease

Search NIH Clinical Center for Bladder Disease

Inferred drug relations via UMLS60/NDF-RT39:

Show with subtypes

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Bladder Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Bladder Disease:
Neo-Urinary Conduit
Embryonic/Adult Cultured Cells Related to Bladder Disease:
Neo-Urinary Conduit, PMID: 22136657

Genetic Tests for Bladder Disease

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Anatomical Context for Bladder Disease

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MalaCards organs/tissues related to Bladder Disease:

31
Testes, Kidney, Heart, Prostate, Smooth muscle, Liver, Appendix

FMA organs/tissues related to Bladder Disease:

14
The bladder

Animal Models for Bladder Disease or affiliated genes

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MGI Mouse Phenotypes related to Bladder Disease:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.6TRPV1, CCK, CHRM3, HBEGF, IDO1

Publications for Bladder Disease

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Articles related to Bladder Disease:

(show top 50)    (show all 160)
idTitleAuthorsYear
1
Re: The Pharmacological rationale for combining muscarinic receptor antagonists and I^-adrenoceptor agonists in the treatment of airway and bladder disease. (25523672)
2015
2
Remodeling of the muscle layer (detrusor muscle) of hyperactive bladder disease in patients with benign prostatic hyperplasia. (23113284)
2012
3
Muscarinic acetylcholine receptor M3 mutation causes urinary bladder disease and a prune-belly-like syndrome. (22077972)
2011
4
The role of sodium hyaluronate and sodium chondroitin sulphate in the management of bladder disease. (22046200)
2011
5
A murine model of inflammatory bladder disease: cathelicidin peptide induced bladder inflammation and treatment with sulfated polysaccharides. (21855919)
2011
6
Overactive bladder disease: the urge for better therapies. (18500915)
2008
7
TRPs in bladder diseases. (17560087)
2007
8
EAU - 15th Congress. Urinary incontinence and bladder disease. (16080050)
2000
9
Long-term follow-up after clam ileocystoplasty. Complications and results including some quality-of-life parameters for 32 patients treated for neuropathic and nonneuropathic bladder disease. (8178380)
1994
10
Is gallbladder ejection fraction a reliable predictor of acalculous gall bladder disease? (8321495)
1993
11
Superficial bladder disease: case studies and therapeutic advances. (1466118)
1992
12
Gall bladder disease as seen in a Harare referral hospital centre. (2225019)
1990
13
Gall bladder disease: an analytical report of 250 cases. (2634700)
1989
14
Parathyroid hormone like bioactivity measured by cytochemical bioassay in a patient with malignant bladder disease. (3248932)
1988
15
A critical reappraisal of cystometry in neurogenic bladder diseases. (3686758)
1987
16
Urine eosinophil cationic protein in painful bladder disease. (3304514)
1987
17
Augmentation cystoplasty in the management of neurogenic bladder disease and urinary incontinence. (3959250)
1986
18
Imaging procedures to diagnose gall bladder disease. (6426669)
1984
19
Diagnosing gall bladder disease. (6428671)
1984
20
Significance of asymptomatic bacteriuria in neurogenic bladder disease. (6369712)
1984
21
The fatty meal and acalculous gall-bladder disease. (6467829)
1984
22
Risk factors for gall-bladder disease: a cohort study of young women attending family planning clinics. (7166683)
1982
23
HIDA scanning in gall-bladder disease. (7437710)
1980
24
Polycystic liver and other hepatic masses mimicking gall-bladder disease. (519149)
1979
25
The use of sacral nerve blocks in the evaluation and treatment of neurologic bladder disease. (904050)
1977
26
Classification of neurogenic bladder disease. (4428539)
1974
27
Gall bladder disease in childhood. (4642203)
1972
28
Gall bladder disease in children. (13978306)
1963
29
CHOLECYSTOGASTROSTOMY IN GALL BLADDER DISEASE. (14062626)
1963
30
Radiological diagnosis of gall bladder disease. (13946048)
1962
31
Myocardial infarction versus gall bladder disease. (13793640)
1960
32
The relationship between heart disease and gall-bladder disease. (13650430)
1959
33
Chronic gall bladder disease. (13584673)
1958
34
Gall bladder disease. (13184295)
1954
35
Practical management of gall bladder disease and its complications. (13149580)
1954
36
Diaphragmatic hernia associated with other gastro-intestinal and gall bladder disease. (18875479)
1948
37
Biliary stasis; the basis of most gall bladder disease. (18106386)
1948
38
On the so-called gall bladder disease. (20267322)
1947
39
Liver damage in gall bladder disease. (20258027)
1947
40
Diagnosis and medical management of gall bladder disease. (20259872)
1947
41
The medical treatment of gall bladder disease. (21001694)
1946
42
Early determination of gall bladder disease and its treatment. (21019023)
1946
43
The Clinical Pathology of Gall-Bladder Disease. (21313354)
1944
44
THE ASSOCIATION OF GALL-BLADDER DISEASE WITH CARDIAC LESIONS. (20320996)
1938
45
On the Mortality Resulting from Surgical Treatment of Chronic Gall-bladder Disease in Diabetes Mellitus. (17866803)
1932
46
OBSCURE GALL-BLADDER DISEASE. (18741249)
1929
47
Gassy Indigestion: Its Significance as a Symptom of Gall Bladder Disease, With a Review of Sixty Cases of Cholecystectomy. (20315666)
1926
48
THE MELTZER-LYONS TEST IN THE DIAGNOSIS OF GALL-BLADDER DISEASE. (17864926)
1923
49
GALL-BLADDER DISEASE IN CHILDHOOD. (17864826)
1923
50
The Symptomatology of Gall-Bladder Disease. (18736005)
1913

Variations for Bladder Disease

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Expression for genes affiliated with Bladder Disease

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Search GEO for disease gene expression data for Bladder Disease.

Pathways for genes affiliated with Bladder Disease

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Pathways related to Bladder Disease according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Translation Non genomic rapid action of Androgen Receptor58
9.5HBEGF, KLK3
2
Show member pathways
Metalloproteases in connective tissue degradation
9.5KLK3, HBEGF
3
Show member pathways
9.0CCK, CHRM3, HBEGF
4
Show member pathways
8.6CCK, CHRM3, TRPV1

Compounds for genes affiliated with Bladder Disease

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Compounds related to Bladder Disease according to GeneCards Suite gene sharing:

(show all 39)
idCompoundScoreTop Affiliating Genes
1dtpa439.9KLK3, CCK
2l-nmma439.9CCK, IDO1
34-diphenylacetoxy-n-methylpiperidine methiodide439.9CCK, CHRM3
4sulfate43 2410.9CCK, HBEGF
5bethanechol43 28 1211.9CCK, CHRM3
6cyproheptadine43 28 1211.8CHRM3, CCK
7pirenzepine43 28 1211.8CCK, CHRM3
8nicardipine43 28 1211.8CCK, CHRM3
9suramin43 28 1211.8KLK3, HBEGF
10atropine43 28 1211.8CHRM3, CCK
115-hydroxytryptamine439.8IDO1, CCK
12carbachol43 28 1211.7CCK, CHRM3
13aspartame43 24 1211.7CCK, TRPV1
14tetrodotoxin43 59 2811.6TRPV1, CCK
15inositol 1,4,5 trisphosphate439.6CCK, CHRM3
16amide439.6TRPV1, CCK
17menthol43 28 24 1212.5IDO1, TRPV1
18morphine43 49 28 1212.5TRPV1, CCK
19cgmp43 2810.5CHRM3, IDO1
20polysaccharide439.5HBEGF, CCK, KLK3
21phorbol 12,13-dibutyrate439.4TRPV1, CHRM3
22lidocaine43 28 1211.4CHRM3, TRPV1
23testosterone43 59 24 1212.4HBEGF, CCK, KLK3
24cycloheximide439.3KLK3, HBEGF, IDO1
25formaldehyde43 2410.3KLK3, TRPV1
26thapsigargin43 5910.2TRPV1, CCK
27inositol439.2TRPV1, CHRM3
28cyclosporin a43 28 5911.0TRPV1, CCK, CHRM3
29dexamethasone43 49 28 1212.0IDO1, HBEGF, CCK, KLK3
30adenylate439.0CHRM3, CCK, TRPV1
31nitric oxide43 24 1210.9IDO1, HBEGF, TRPV1
32oxygen43 249.7IDO1, HBEGF, TRPV1
33glucose438.7CCK, CHRM3, HBEGF
34pge2438.7TRPV1, CCK, HBEGF, IDO1
35glutamate438.7TRPV1, CCK, HBEGF, IDO1
36atp43 289.6TRPV1, CHRM3, HBEGF
37cysteine438.5HBEGF, CHRM3, TRPV1
38tyrosine438.1IDO1, HBEGF, CHRM3, CCK, TRPV1
39calcium43 49 24 1211.0IDO1, HBEGF, CHRM3, CCK, TRPV1

GO Terms for genes affiliated with Bladder Disease

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Cellular components related to Bladder Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1postsynaptic membraneGO:00452119.0TRPV1, CHRM3
2integral component of plasma membraneGO:00058878.3TRPV1, CHRM3, HBEGF

Biological processes related to Bladder Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1signal transductionGO:00071659.0CCK, CHRM3, HBEGF

Products for genes affiliated with Bladder Disease

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  • Antibodies
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  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Bladder Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet