MCID: BLS002
MIFTS: 51

Blastomycosis malady

Infectious diseases category

Summaries for Blastomycosis

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8Disease Ontology, 42NIH Rare Diseases, 3CDC, 63Wikipedia, 32MalaCards
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NIH Rare Diseases:42 Blastomycosis is a rare infection that may develop when people inhale a fungus called blastomyces dermatitidis, a fungus that is found in moist soil, particularly where there is rotting vegetation. the fungus enters the body through the lungs, infecting them. the fungus then spreads to other areas of the body. the infection may affect the skin, bones and joints, and other areas. the disease usually affects people with weakened immune systems, such as those with hiv or who have had an organ transplant. last updated: 12/9/2011

MalaCards: Blastomycosis, also known as north american blastomycosis, is related to histoplasmosis and malignant hyperthermia, and has symptoms including pleural thickening, lung lesions and skin lesions. An important gene associated with Blastomycosis is ALB (albumin). The drugs fluconazole and ketoconazole and the compound calcium have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and bone.

Disease Ontology:8 A primary systemic mycosis that results in a systemic fungal infection, has material basis in blastomyces dermatitidis, transmitted by airborne spores and has symptom skin lesions, has symptom lung lesions and has symptom pleural thickening.

CDC:3 Blastomycosis is a disease caused by the fungus Blastomyces dermatitidis. The fungus lives in moist soil and in association with decomposing organic matter such as wood and leaves. Lung infection can occur after a person inhales airborne, microscopic fungal spores from the environment; however, many people who inhale the spores do not get sick. The symptoms of blastomycosis are similar to flu symptoms, and the infection can sometimes become serious if it is not treated.

Wikipedia:63 Blastomycosis (also known as \"North American blastomycosis\", \"Blastomycetic dermatitis\", and... more...

Aliases & Classifications for Blastomycosis

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

blastomycosis 8 42 10 60
north american blastomycosis 8 42
other dermatophytosis 8 60
gilchrist's disease 8 42
infection by blastomyces dermatitidis 8
blastomycosis & chicago disease 8
blastomyces dermatitidis infection 8
blastomycotic infection nos 8
blastomycosis, unspecified 8
blastomycotic infection 8
gilchrists disease 8
blastomycosis nos 8
gilchrist disease 60
chicago disease 8
north american 8


External Ids:

Disease Ontology8 DOID:12663
MeSH34 D001759
ICD9CM27 116, 116.0
ICD1025 B40, B40.9

Related Diseases for Blastomycosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Blastomycosis:



Diseases related to blastomycosis

Clinical Features for Blastomycosis

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8Disease Ontology
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Symptoms:

8
  • pleural thickening
  • lung lesions
  • skin lesions

Drugs & Therapeutics for Blastomycosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Blastomycosis

Drug clinical trials:

Search ClinicalTrials for Blastomycosis

Search NIH Clinical Center for Blastomycosis

Search CenterWatch for Blastomycosis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Blastomycosis

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Anatomical Context for Blastomycosis

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32MalaCards
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MalaCards organs/tissues related to Blastomycosis:

32
Lung, Skin, Bone, Testes, Thyroid, Prostate, Lymph node, Brain, Spinal cord, Eye, Breast, Myeloid

Animal Models for Blastomycosis or affiliated genes

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Publications for Blastomycosis

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50PubMed
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Articles related to Blastomycosis:

(show top 50)    (show all 503)
idTitleAuthorsYear
1
Rare systemic mycoses in cats: blastomycosis, histoplasmosis and coccidioidomycosis: ABCD guidelines on prevention and management. (23813828)
2013
2
Prevalence and geographic distribution of canine and feline blastomycosis in the Canadian prairies. (24155475)
2013
3
Unusual osseous presentation of blastomycosis in an immigrant child: a challenge for European pediatricians. (23228191)
2012
4
Blastomycosis presenting as solitary nodule: a rare presentation. (22615513)
2012
5
Radiologic case study. Blastomycosis of bone. (21661669)
2011
6
Blastomycosis of the central nervous system in a child: a rare cause of hypopituitarism. (22145474)
2011
7
Non-rural point source blastomycosis outbreak near a yard waste collection site. (20974888)
2011
8
The differential diagnosis of pulmonary blastomycosis using case vignettes: a Wisconsin Network for Health Research (WiNHR) study. (21560560)
2011
9
Blastomycosis: a differential diagnosis of periampullary tumors. (20861704)
2010
10
Successful treatment of choroidal blastomycosis with oral administration of voriconazole. (19491993)
2009
11
A case-control study of sporadic canine blastomycosis in Tennessee, USA. (18654918)
2008
12
Antigen and antibody testing for the diagnosis of blastomycosis in dogs. (18482276)
2008
13
Systemic blastomycosis diagnosed by prostate needle biopsy. (18591374)
2008
14
Blastomycosis-like pyoderma. (17456921)
2007
15
Blastomyces antigen detection for monitoring progression of blastomycosis in a pregnant adolescent. (17641724)
2007
16
Blastomycosis in a young African man presenting with a pleural effusion. (17149463)
2006
17
Human and canine pulmonary blastomycosis, North Carolina, 2001-2002. (16965704)
2006
18
Nonoperative treatment of vertebral blastomycosis osteomyelitis associated with paraspinal abscess and cord compression. A case report. (16595477)
2006
19
Cutaneous blastomycosis in a cat. (16443849)
2006
20
Intramedullary blastomycosis in a child: case report. (15198461)
2004
21
Pulmonary blastomycosis: an appraisal of diagnostic techniques. (11888958)
2002
22
Blastomycosis acquired by three children in Toronto. (18159399)
2002
23
Clinical Images: Arthritis induced by South American blastomycosis. (11229487)
2001
24
Acute respiratory distress syndrome from blastomycosis: a case report. (11816781)
2001
25
Blastomycosis of the petrous apex. (11241008)
2001
26
Chronic paronychia, osteomyelitis, and paravertebral abscess in a child with blastomycosis. (11033269)
2000
27
Blastomycosis granuloma involving the cranial vena cava associated with chylothorax and cranial vena caval syndrome in a dog. (10730627)
2000
28
Thoracic and abdominal blastomycosis in a horse. (10319179)
1999
29
Unusual clinical forms of south american blastomycosis. Report of two new cases. (11507531)
1999
30
Intracranial blastomycosis presenting as a suprasellar mass: MR findings. (9294589)
1997
31
Epidemiological and clinical features of pulmonary blastomycosis. (9313292)
1997
32
Blastomycosis in the immunocompromised patient. (9313296)
1997
33
Blastomycosis. Report of a case with noninvasive, rapid diagnosis of dermal lesions by the Papanicolaou technique. (9990284)
1997
34
Efficacy of nikkomycin Z against experimental pulmonary blastomycosis. (9303408)
1997
35
Blastomycosis-induced respiratory failure: the successful application of continuous positive airway pressure. (9315471)
1997
36
Blastomycosis of the eyelid. (8618747)
1996
37
Pediatric spinal blastomycosis: case report. (7501124)
1995
38
Indications for the surgical management of central nervous system blastomycosis. (7792710)
1995
39
Itraconazole for the treatment of histoplasmosis and blastomycosis. (18611672)
1995
40
Blastomycosis of the skull base. (17170892)
1993
41
Favourable outcome of blastomycosis of the brain stem with fluconazole and flucytosine treatment. (1575964)
1992
42
Pseudo-outbreak of blastomycosis associated with contaminated bronchoscopes. (1619267)
1992
43
Cutaneous blastomycosis. (1486793)
1992
44
Blastomycosis: fungal infections of the lung update: 1989. (2247705)
1990
45
Disseminated blastomycosis in a pregnant woman successfully treated with amphotericin-B. A case report. (3385706)
1988
46
A canine case of North American blastomycosis in Alberta, Canada. (3200260)
1988
47
Ketoconazole in the treatment of paracoccidioidomycosis (South American blastomycosis). Experience in 30 cases in Bolivia. (3405248)
1988
48
Blastomycosis. (3695468)
1987
49
Splenic abscess due to blastomycosis: scintigraphic, sonographic, and CT evaluation. (6600327)
1983
50
Cicatricial ectropion caused by cutaneous blastomycosis. (13507786)
1958

Genetic Variations for Blastomycosis

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Expression for genes affiliated with Blastomycosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Blastomycosis

Search GEO for disease gene expression data for Blastomycosis.

Pathways for genes affiliated with Blastomycosis

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Compounds for genes affiliated with Blastomycosis

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44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB
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Compounds related to Blastomycosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium44 49 11 2411.1ALB, SLA2, PKD2L1, KCNB1

GO Terms for genes affiliated with Blastomycosis

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16Gene Ontology
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Molecular functions related to Blastomycosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein N-terminus bindingGO:0474859.1SLA2, KCNB1

Products for genes affiliated with Blastomycosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Blastomycosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet