Aliases & Classifications for Blepharochalasis

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Aliases & Descriptions for Blepharochalasis:

Name: Blepharochalasis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:348
ICD1027 H02.3
ICD9CM29 374.34
UMLS65 C0005742

Summaries for Blepharochalasis

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Wikipedia:68 Blepharochalasis is an inflammation of the eyelid that is characterized by exacerbations and remissions... more...

MalaCards based summary: Blepharochalasis is related to ascher syndrome and amyloidosis aa, and has symptoms including eyelash injury, lacrimal punctum enlarged and eyelid skin dryness. An important gene associated with Blepharochalasis is GSN (Gelsolin), and among its related pathways are Osteopontin-mediated events and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include skin, b cells and prostate, and related mouse phenotypes are homeostasis/metabolism and hematopoietic system.

Related Diseases for Blepharochalasis

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Diseases related to Blepharochalasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 74)
idRelated DiseaseScoreTop Affiliating Genes
1ascher syndrome11.7
2amyloidosis aa10.6GSN, TTR
3lethal congenital contracture syndrome 110.6GSN, TTR
4uterine inversion10.6CD79A, TTR
5hereditary antithrombin deficiency10.6GSN, TTR
6carpal tunnel syndrome, familial10.6GSN, TTR
7salpingitis isthmica nodosa10.6GSN, TTR
8chest wall lymphoma10.5CD79A, TTR
9alopecia-mental retardation syndrome 310.5GSN, TTR
10chronic subinvolution of uterus10.5CD68, OSMR
11cryopyrin-associated periodic syndrome10.4CD79A, FN1
12amyloidosis beta2m10.4SAA1, TTR
13mucinoses10.4CD79A, FN1
14ectopic thymus10.4CD68, CD79A
15pediatric meningioma10.4CD68, CD79A
16cicatricial pemphigoid10.4CD68, TTR
17differentiating neuroblastoma10.4CD79A, FN1
18bladder neck cancer10.4CD79A, TTR
19small intestinal vasoactive intestinal peptide producing tumor10.4CD79A, TTR
20lemierre's syndrome10.4CD68, CD79A
21pervasive developmental disorder10.4CD79A, FN1
22optic neuritis10.4CD79A, FN1
23anatomical narrow angle borderline glaucoma10.3CD79A, MMP9
24cervical incompetence10.3CD68, CD79A
25clear cell ependymoma10.3CD68, TTR
26tricuspid valve disease10.3CD79A, FN1
27hypersensitivity reaction type ii disease10.3CD79A, FN1
28otomycosis10.3CD68, CD79A
29monocular exotropia10.3CD68, CD79A
30septic myocarditis10.3CD68, FN1
31biliary atresia10.2CD79A, TTR
32afibrinogenemia, congenital10.2GSN, SAA1, TTR
33al gazali aziz salem syndrome10.2CD68, TTR
34entropion10.2MMP3, MMP9
35anterograde amnesia10.2MMP3, MMP9
36pediatric fibrosarcoma10.2CD68, FN1
37neurofibromatosis, type 210.2MMP3, MMP9
38immunodeficiency 27b, mycobacteriosis, ad10.2MMP3, MMP9
39conjunctival disease10.2MMP3, MMP9
40lacrimal system cancer10.2CD79A, FN1
41grade iii astrocytoma10.2MMP3, MMP9
42staphyloenterotoxemia10.2CD68, FN1
43renal pelvis adenocarcinoma10.2FN1, MMP9
44meibomian cyst10.1CD68, MMP9
45homocystinuria10.1CD79A, MMP9
46lower lip cancer10.1MMP3, MMP9
47gastrointestinal carcinoma10.1CD68, MMP9
48macular degeneration, age-related, 1110.1GSN, TTR
49ptosis10.1
50cyclotropia10.1LAX1, TTR

Graphical network of the top 20 diseases related to Blepharochalasis:



Diseases related to blepharochalasis

Symptoms for Blepharochalasis

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UMLS symptoms related to Blepharochalasis:


eyelash injury, lacrimal punctum enlarged, eyelid skin dryness, eyelids (symptom), lid, lash and lacrimal structural disorders, retraction of eyelid

Drugs & Therapeutics for Blepharochalasis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Astigmatic Changes Secondary to Eyelid SurgeriesRecruitingNCT01968174
2Assessment of Changes of Periocular Skin Sensation Following Eyelid and Ocular Surface SurgeriesNot yet recruitingNCT02638610
3Levator Muscle Strength EvaluationNot yet recruitingNCT02226016

Search NIH Clinical Center for Blepharochalasis

Genetic Tests for Blepharochalasis

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Anatomical Context for Blepharochalasis

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MalaCards organs/tissues related to Blepharochalasis:

33
Skin, B cells, Prostate, Eye, T cells, Endothelial, Pituitary

Animal Models for Blepharochalasis or affiliated genes

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MGI Mouse Phenotypes related to Blepharochalasis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.1CD79A, FN1, GSN, MMP3, MMP9, OSMR
2MP:00053976.6CD68, CD79A, FN1, GSN, LAX1, MMP3
3MP:00053876.3CD68, CD79A, FN1, GSN, LAX1, MMP3

Publications for Blepharochalasis

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Articles related to Blepharochalasis:

(show top 50)    (show all 61)
idTitleAuthorsYear
1
Recurrent ptosis in a patient with blepharochalasis: clinical and histopathologic findings. (25569415)
2015
2
Blepharochalasis with double lip: A case of Ascher syndrome. (26515861)
2015
3
Blepharochalasis with double lip: A case of Ascher syndrome. (26087089)
2015
4
Unilateral blepharochalasis of right eye. (25284875)
2014
5
Blepharochalasis showing prominent infiltration of neutrophils in dermal vessels. (25292259)
2014
6
Langerhans cell disease of the eyelids masquerading as blepharochalasis. (24224501)
2014
7
Blepharochalasis: possibly associated with matrix metalloproteinases. (24815765)
2014
8
Transcutaneous blepharoplasty in blepharochalasis. (23378713)
2012
9
Acute episode of eyelid oedema. Blepharochalasis. (22467940)
2012
10
Doxycycline for treatment of blepharochalasis via inhibition of matrix metalloproteinases. (21946773)
2012
11
Successful medical treatment of blepharochalasis: a case series. (19874128)
2009
12
Blepharochalasis: a rare condition misdiagnosed as recurrent angioedema. (19380685)
2009
13
The blepharochalasis syndrome. (19298902)
2009
14
Blepharochalasis. (19293520)
2009
15
Blepharochalasis--a rare entity. (18319025)
2008
16
Oral acetazolamide: A treatment option for blepharochalasis? (19668490)
2007
17
Bilateral blepharochalasis. (16268879)
2005
18
Elastin gene expression in blepharochalasis. (15841657)
2005
19
Lacrimal gland prolapse in blepharochalasis. (15069442)
2004
20
Blepharochalasis misdiagnosed as allergic recurrent angioedema. (14616136)
2003
21
Unilateral blepharochalasis. (12859930)
2003
22
Blepharochalasis. (17664751)
2001
23
Bilateral eyelid edema: cutis laxa or blepharochalasis? (11092366)
2000
24
Immunoglobulin A (IgA) deposits in lesional skin of a patient with blepharochalasis. (8977684)
1996
25
Blepharochalasis. (20952919)
1995
26
Localised unilateral blepharochalasis. (7848988)
1994
27
Mental retardation, microcephaly and blepharochalasis in brothers. (8055132)
1994
28
Blepharochalasis associated with dermatomyositis and acute lymphocytic leukemia. (1598975)
1992
29
Blepharochalasis syndrome: a proposed pathophysiologic mechanism. (1555128)
1992
30
Blepharochalasis. A review of 30 cases. (1911519)
1991
31
A review of blepharochalasis and other causes of the lax, wrinkled eyelid. (2178883)
1990
32
The Blepharochalasis syndrome. (2244849)
1990
33
Blepharochalasis and dermatochalasis. (3183270)
1988
34
Blepharochalasis. (3207663)
1988
35
Unilateral blepharochalasis. (3658315)
1987
36
Floppy eyelid syndrome and blepharochalasis. (3752204)
1986
37
Blepharochalasis after a bee sting. (6718584)
1984
38
Blepharochalasis with multiple system involvement. (6743619)
1984
39
Blepharochalasis--a case report. (6545239)
1984
40
Dermatochalasis and blepharochalasis of the upper lids. (724217)
1978
41
Blepharo-confusion--blepharochalasis or dermatochalasis? (655933)
1978
42
Self-induced blepharochalasis in a case of facial palsy. (924618)
1977
43
The history of blepharoplasty to correct blepharochalasis. (24173743)
1976
44
Blepharochalasis. (4824166)
1974
45
Double lip and double lip with blepharochalasis (Ascher's syndrome). (4507440)
1972
46
Blepharochalasis in upper eyelids; including its classification. (13424625)
1957
47
Correction of senile atrophy of eyelid and blepharochalasis. (13200538)
1954
48
Blepharochalasis. (14877956)
1951
49
Blepharochalasis (Ptosis adiposa). (19974024)
1909
50

Variations for Blepharochalasis

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Expression for genes affiliated with Blepharochalasis

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Search GEO for disease gene expression data for Blepharochalasis.

Pathways for genes affiliated with Blepharochalasis

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GO Terms for genes affiliated with Blepharochalasis

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Biological processes related to Blepharochalasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endodermal cell differentiationGO:00359879.6FN1, MMP9
2extracellular matrix disassemblyGO:00226178.6FN1, GSN, MMP3, MMP9

Sources for Blepharochalasis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet