MCID: BLN006
MIFTS: 28

Blind Loop Syndrome malady

Categories: Gastrointestinal diseases

Aliases & Classifications for Blind Loop Syndrome

Aliases & Descriptions for Blind Loop Syndrome:

Name: Blind Loop Syndrome 12 42 14 69
Bacterial Overgrowth Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10606
ICD10 33 K90.2
ICD9CM 35 579.2
MeSH 42 D001765
NCIt 47 C34431
SNOMED-CT 64 66379009 77225009
UMLS 69 C0005750

Summaries for Blind Loop Syndrome

Disease Ontology : 12 An intestinal disease characterized by a dysbalance of the bacterial flora of the small intestine, causing derangement to the normal physiological processes of digestion and absorption.

MalaCards based summary : Blind Loop Syndrome, also known as bacterial overgrowth syndrome, is related to mucositis and arthritis. An important gene associated with Blind Loop Syndrome is GIF (Gastric Intrinsic Factor). The drugs Aspirin and Nitroglycerin have been mentioned in the context of this disorder. Affiliated tissues include small intestine and testes.

Wikipedia : 71 Blind loop syndrome (BLS), commonly referred to in the literature as small intestinal bacterial... more...

Related Diseases for Blind Loop Syndrome

Diseases related to Blind Loop Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
id Related Disease Score Top Affiliating Genes
1 mucositis 9.8
2 arthritis 9.7
3 steatorrhea 9.7
4 tropical sprue 9.7
5 duodenal obstruction 9.7
6 duodenitis 9.7
7 neuropathy 9.7
8 muscular dystrophy 9.7
9 gastroparesis 9.7
10 constipation 9.7
11 cholangitis 9.6
12 osteomalacia 9.6
13 spinocerebellar degeneration 9.6
14 protein-losing enteropathy 9.6
15 megaesophagus 9.6
16 megaloblastic anemia 9.6
17 panniculitis 9.6
18 dermatitis 9.6
19 reactive arthritis 9.6
20 pancreatic steatorrhea 9.4 GCG GIF TNFAIP3 XK

Comorbidity relations with Blind Loop Syndrome via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Blind Loop Syndrome:



Diseases related to Blind Loop Syndrome

Symptoms & Phenotypes for Blind Loop Syndrome

Drugs & Therapeutics for Blind Loop Syndrome

Drugs for Blind Loop Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 96)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
2
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
3
Pravastatin Approved Phase 4 81093-37-0 54687
4
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
5
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2 54-31-9 3440
6
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
7
Bumetanide Approved Phase 4 28395-03-1 2471
8
Chlorthalidone Approved Phase 4 77-36-1 2732
9
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
10
Chlorothiazide Approved, Vet_approved Phase 4 58-94-6 2720
11
Metolazone Approved Phase 4 17560-51-9 4170
12
Clopidogrel Approved, Nutraceutical Phase 4 120202-66-6, 113665-84-2 60606
13 Analgesics Phase 4
14 Analgesics, Non-Narcotic Phase 4
15 Anti-Inflammatory Agents Phase 4
16 Anti-Inflammatory Agents, Non-Steroidal Phase 4
17 Antipyretics Phase 4
18 Antirheumatic Agents Phase 4
19 Cyclooxygenase Inhibitors Phase 4
20 Fibrinolytic Agents Phase 4
21 Peripheral Nervous System Agents Phase 4
22 Platelet Aggregation Inhibitors Phase 4
23 Anticholesteremic Agents Phase 4
24 Antimetabolites Phase 4
25 Atorvastatin Calcium Phase 4 134523-03-8
26 Calcium, Dietary Phase 4
27 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
28 Hypolipidemic Agents Phase 4
29 Lipid Regulating Agents Phase 4
30 calcium heparin Phase 4
31 diuretics Phase 4,Phase 3,Phase 2
32 Natriuretic Agents Phase 4,Phase 3,Phase 2
33 Sodium Potassium Chloride Symporter Inhibitors Phase 4,Phase 3,Phase 2
34 Anticonvulsants Phase 4
35 Carbonic Anhydrase Inhibitors Phase 4
36 Diuretics, Potassium Sparing Phase 4
37 Hormone Antagonists Phase 4
38 Hormones Phase 4
39 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
40 Mineralocorticoid Receptor Antagonists Phase 4
41 Mineralocorticoids Phase 4
42 Chinese Salvia Nutraceutical Phase 4
43
Adenosine Approved, Investigational Phase 3 58-61-7 60961
44
Empagliflozin Approved Phase 2, Phase 3 864070-44-0
45 Neurotransmitter Agents Phase 3
46 Purinergic P1 Receptor Antagonists Phase 3
47
Rolofylline Phase 3 136199-02-5 8530
48 Hypoglycemic Agents Phase 2, Phase 3
49
Ginseng Approved, Nutraceutical Phase 2 50647-08-0
50 Pharmaceutical Solutions Phase 2

Interventional clinical trials:

(show all 44)
id Name Status NCT ID Phase
1 Efficacy and Safety of Qizhitongluo Capsule in the Recovery Phase of Ischemic Stroke Completed NCT01762163 Phase 4
2 Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index Completed NCT01502943 Phase 4
3 Aqueous Flare of a Hydrophobic Acrylic Single-piece Open-loop IOL With Modified Material Surface Properties Completed NCT01767012 Phase 4
4 The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients Recruiting NCT02850627 Phase 4
5 Danhong Injection in the Treatment of Acute Ischemic Stroke Recruiting NCT01677208 Phase 4
6 Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure Recruiting NCT01973335 Phase 4
7 Effectiveness and Safety of Yiqitongluo Granule for Stroke Enrolling by invitation NCT02604654 Phase 4
8 Protocolized Diuretic Strategy in Cardiorenal Failure Terminated NCT01921829 Phase 4
9 PROTECT-2: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitalized With Acute HF and Volume Overload to Assess Treatment Effect on Congestion and Renal Function Completed NCT00354458 Phase 3
10 PROTECT-1: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitalized With Acute HF and Volume Overload to Assess Treatment Effect on Congestion and Renal Function Completed NCT00328692 Phase 3
11 Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study) Completed NCT00577135 Phase 3
12 Effects of the SGLT2-inhibitor Empagliflozin on Patients With SIADH - the SAND Study Enrolling by invitation NCT02874807 Phase 2, Phase 3
13 The Study of MicroRNA Genomics of Blood Stasis Syndrome and of Coronary Heart Disease Unknown status NCT01615003 Phase 2
14 Multicentre, Randomized, Controlled Trial of Qideng Mingmu Capsule in The Treatment of Diabetic Retinopathy Completed NCT01373476 Phase 2
15 Observing the Curative Effect of Assisted Reproduction by TCM Multi-channel Interventional Therapy Completed NCT02303665 Phase 2
16 Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome Completed NCT00858130 Phase 2
17 Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Non-ST Elevation Myocardial Infarction Completed NCT01491074 Phase 2
18 The Efficacy and Safety of the Xu-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome. Recruiting NCT03091634 Phase 2
19 A Clinical Research of Qi Deficiency and Blood Stasis Syndrome (Different Disease With Syndrome) Recruiting NCT02875639 Phase 2
20 Efficacy and Safety of Xuesaitong Soft Capsule for Coronary Heart Disease Unstable Angina Recruiting NCT03083119 Phase 2
21 Observation on the Curative Effect of Assisted Reproduction by TCM Multi-channel Interventional Therapy Recruiting NCT03078205 Phase 2
22 Uncut Roux-en-Y Gastrojejunostomy for Early Gastric Cancer Patients Recruiting NCT02644148 Phase 2
23 Concentrated Saline Infusions and Increased Dietary Sodium With Diuretics for Heart Failure With Kidney Dysfunction Terminated NCT00575484 Phase 2
24 A Phase I Safety and Immunogenicity Trial of HIV-1 gp120 C4-V3 Hybrid Polyvalent Peptide Immunogen Mixed in Mineral Oil Containing Mannose Mono-Oleate (IFA) Completed NCT00000886 Phase 1
25 Comparison Between Erythromycin and Neomycin Treatment of Hepatic Encephalopathy Unknown status NCT01097811
26 A Study Comparing Billroth II With Roux-en-Y Reconstruction for Gastric Cancer Unknown status NCT01257711
27 Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants Unknown status NCT02249143
28 Algorithm for Oliguria in Septic Shock Unknown status NCT02338895
29 Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing Completed NCT01324895
30 Dynamic Combination Therapy on Chinese Herbal Granules to Improve the Symptoms in Convalescent Phase of Ischemic Stroke Completed NCT01780480
31 Clinical Application and Basic Study of Medicinal Fractions-based Herbal Combinations Completed NCT01636154
32 Impact of Braun Anastomosis on Reduction in Delayed Gastric Emptying Following Pancreaticoduodenectomy Completed NCT01787955
33 Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions Completed NCT02708277
34 Miofascial Release and Exercises Therapy in the Treatment of Temporomandibular Disorders Completed NCT02540863
35 Physiotherapy and Deontology in the Temporomandibular Joint Dysfunction in Patients With Fibromyalgia Syndrome. Completed NCT01800279
36 Combination Therapy to Treat Sleep Apnea Completed NCT01633827
37 Screening Protein Markers in Patients With Rheumatoid Arthritis and Hot-dampness and Blood Stasis Syndrome Recruiting NCT02408094
38 Innovation Research of Differentiation and Treatment Methods Based on CHD Phlegm and Blood Stasis Syndrome Recruiting NCT02967718
39 Small Intestinal Bacterial Overgrowth Obese Recruiting NCT02819037
40 Yiqi Huoxue Demolition and Recipes on Recovery Stage of Cerebral Infarction Recruiting NCT02846207
41 Clinical Study On The Relation Among Prescription, Syndrome and Disease of Turbid Phlegm and Blood Stasis for Coronary Heart Disease Recruiting NCT02526381
42 Heat-clearing and Blood-activating Chinese Medicinal Components in Acute Cerebral Infarction Recruiting NCT02544087
43 Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonlein Purpura Nephritis Enrolling by invitation NCT02878018
44 Clinical Trial of PSORI-CM01(YXBCM01) Granule to Treat Stable Plaque Psoriasis Terminated NCT02153840

Search NIH Clinical Center for Blind Loop Syndrome

Cochrane evidence based reviews: blind loop syndrome

Genetic Tests for Blind Loop Syndrome

Anatomical Context for Blind Loop Syndrome

MalaCards organs/tissues related to Blind Loop Syndrome:

39
Small Intestine, Testes

Publications for Blind Loop Syndrome

Articles related to Blind Loop Syndrome:

(show top 50) (show all 77)
id Title Authors Year
1
A Case of Blind Loop Syndrome Caused by Infection with Giardia duodenalis Diagnosed with Double Balloon Enteroscopy. ( 25408630 )
2014
2
Migrating motor complex changes after side-to-side ileal bypass in mouse ileum ex-vivo: mechanism underlying the blind loop syndrome? ( 22066044 )
2011
3
Reversible acute reactive arthritis secondary to iatrogenic blind loop syndrome. ( 17925936 )
2007
4
Absorbable vs. non-absorbable antibiotics in the treatment of small intestine bacterial overgrowth in patients with blind-loop syndrome. ( 15813834 )
2005
5
Blind loop syndrome after biliopancreatic diversion: a diagnostic challenge. ( 11594112 )
2001
6
Blind loop syndrome. Diagnosis by In-111-labeled leukocyte scintigraphy. ( 10439196 )
1999
7
Blind loop syndrome: an unusual cause of panniculitis. ( 9366844 )
1997
8
Blind loop syndrome: multiple ileal ulcers following side-to-side anastomosis. ( 8165008 )
1993
9
The blind loop syndrome in children. ( 2401946 )
1990
10
The deconjugation ability of bacteria isolated from the jejunal fluids in the blind loop syndrome with high 14CO2 excretion--using the breath analysis technique and thin-layer chromatography. ( 2513463 )
1989
11
Percutaneous duodenostomy in blind loop syndrome. ( 2451880 )
1988
12
Impaired intestinal sodium and chloride transport in the blind loop syndrome of the rat. ( 2434383 )
1987
13
Adaptation of the jejunal mucosa in the experimental blind loop syndrome: changes in paracellular conductance and tight junction structure. ( 3692303 )
1987
14
Ischemic jejunal stenosis and blind loop syndrome after blunt abdominal trauma. ( 3559122 )
1987
15
Postgastrectomy blind loop syndrome and the arthritis-dermatitis syndrome. ( 3970735 )
1985
16
Blind loop syndrome, vitamin E malabsorption, and spinocerebellar degeneration. ( 3974892 )
1985
17
Choledochoduodenostomy and the blind loop syndrome. ( 4041721 )
1985
18
Breath hydrogen test in infants and children with blind loop syndrome. ( 6737180 )
1984
19
Altered motility and duration of bacterial overgrowth in experimental blind loop syndrome. ( 6376005 )
1984
20
Altered myoelectric activity in the experimental blind loop syndrome. ( 6350361 )
1983
21
Blind loop syndrome and small bowel bacterial contamination. ( 6347463 )
1983
22
Blind loop syndrome following iatrogenic intestinal bypass in a child. ( 7141516 )
1982
23
Glycoprotein degradation in the blind loop syndrome: identification of glycosidases in jejunal contents. ( 6257760 )
1981
24
Protein-losing enteropathy in the human and experimental rat blind-loop syndrome. ( 7450442 )
1981
25
Importance of anaerobic bacteria in the cobalamin malabsorption of the experimental rat blind loop syndrome. ( 7450422 )
1981
26
Gut damage in human blind-loop syndrome. ( 7239120 )
1981
27
Sensitivity of bile acid breath test in the diagnosis of bacterial overgrowth in the small intestine with and without the stagnant (blind) loop syndrome. ( 428288 )
1979
28
Osteomalacia complicating a blind loop syndrome from congenital megaesophagus-megaduodenum. ( 439112 )
1979
29
Protein digestion and absorption in the blind loop syndrome. ( 510093 )
1979
30
Enterotoxigenicity of colonising coliform bacteria in tropical sprue and blind-loop syndrome. ( 79710 )
1978
31
Pathogenesis of mucosal injury in the blind loop syndrome. ( 359400 )
1978
32
Xylose catabolism in the experimental rat blind loop syndrome: studies, including use of a newly developed d-[14C]xylose breath test. ( 631506 )
1978
33
Brush border peptidases and arylamidases in the experimental blind loop syndrome of the rat. ( 930537 )
1977
34
Diagnosis of blind-loop syndrome by X-ray/breath-hydrogen test. ( 64837 )
1977
35
Pathogenesis of mucosal injury in the blind loop syndrome. Brush border enzyme activity and glycoprotein degradation. ( 410830 )
1977
36
Intestinal blind pouch- and blind loop- syndrome in children operated previously for congenital duodenal obstruction. ( 1032876 )
1976
37
Gastrointestinal bleeding and iron absorption in the experimental blind loop syndrome. ( 1084685 )
1976
38
Enzyme activities of jejunal mucosa in experimental blind loop syndrome of rat. ( 6913 )
1976
39
Intestinal blind pouch- and blind loop-syndrome in children operated previously for congenital duodenal obstruction. ( 1267407 )
1976
40
Functional, biochemical and morphological alterations in the intestines of rats with an experimental blind-loop syndrome. ( 1202590 )
1975
41
Small intestinal mucosal injury in the experimental blind loop syndrome. Light- and electron-microscopic and histochemical studies. ( 1126607 )
1975
42
Kinetics of bile acid metabolism in experimental blind loop syndrome. ( 1218814 )
1975
43
The uptake of vitamin B12 by the sediment of jejunal contents in patients with the blind-loop syndrome. ( 1138334 )
1975
44
The absorption of vitamin B12 in the blind-loop syndrome. ( 4215127 )
1974
45
Jejunal brush border injury and impaired sugar and amino acid uptake in the blind loop syndrome. ( 4426497 )
1974
46
Blind loop syndrome. ( 4594535 )
1974
47
Blind loop syndrome associated with growth retardation. ( 4847713 )
1974
48
Steatorrhoea and the blind-loop syndrome. ( 4119959 )
1973
49
The mechanism of vitamin B 12 malabsorption in blind-loop syndrome. ( 4572448 )
1973
50
The blind-loop syndrome and its variants. Microbiologic aspects of diagnosis and treatment. ( 4583160 )
1973

Variations for Blind Loop Syndrome

Expression for Blind Loop Syndrome

Search GEO for disease gene expression data for Blind Loop Syndrome.

Pathways for Blind Loop Syndrome

GO Terms for Blind Loop Syndrome

Sources for Blind Loop Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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