| 1 | GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness. (22325362) | Peachey N.S.... Gregg R.G. | 2012 | GPR179 |
| 2 | Establishing optimal selenium status: results of a ra ndomized, double-blind, placebo-controlled trial. (20181815) | Hurst R.... Fairweather-Tait S.J. | 2010 | SEPP1 |
| 3 | A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer. (19409038) | Horti J.... Bodrogi I. | 2009 | EGFR |
| 4 | Effects of grape seed extract in Type 2 diabetic subj ects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stres s and insulin sensitivity. (19646193) | Kar P.... Cummings M. | 2009 | ALB, INS |
| 5 | Postprandial ghrelin responses are associated with th e intermeal interval in time-blinded normal weight men, but not in obese men. (19385031) | Blom W.A.... Hendriks H.F. | 2009 | GHRL |
| 6 | Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide. (19139391) | Schmieder R.E.... van Ingen H. | 2009 | REN |
| 7 | The effect of exogenous glucagon-like peptide-1 on th e glycaemic response to small intestinal nutrient in the critically ill: a rand omised double-blind placebo-controlled cross over study. (19439067) | Deane A.M.... Horowitz M. | 2009 | GCG |
| 8 | Parecoxib versus dipyrone (metamizole) for postoperat ive pain relief after hysterectomy : a prospective, single-centre, randomized, double-blind trial. (18544002) | Soltesz S.... Molter G. | 2008 | PTGS2 |
| 9 | Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial. (18358927) | Yokota S.... Kishimoto T. | 2008 | CRP |
| 10 | Pharmacokinetic and pharmacodynamic assessments of the dipeptidyl peptidase-4 inhibitor PHX1149: double-blind, placebo-controlled, single- and multiple-dose studies in healthy subjects. (17919550) | O'Farrell A.M.... Guler H.P. | 2007 | DPP4 |
| 11 | Beneficial effects of C1 esterase inhibitor in ST-elevation myocardial infarction in patients who underwent surgical reperfusion: a randomised double-blind study. (17576071) | Fattouch K.... Ruvolo G. | 2007 | C1S |
| 12 | A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis. (17519075) | Gottlieb A.B.... Mascelli M.A. | 2007 | IL8, IL18, IFNG |
| 13 | Randomized, double-blind, placebo-controlled trial of bovine lactoferrin in patients with chronic hepatitis C. (16984383) | Ueno H.... Okusaka T. | 2006 | LTF |
| 14 | A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease. (16630771) | Zelber-Sagi S.... Oren R. | 2006 | INS |
| 15 | Aggressive antihypertensive therapy based on hydrochlorothiazide, candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals: effects on albumin excretion, endothelial function and inflammation in a double-blind, randomized clinical trial. (15647778) | Schram M.T.... Stehouwer C.D. | 2005 | ALB |
| 16 | Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial. (15925816) | Polychronis A.... Coombes R.C. | 2005 | EGFR, ESR1, EREG |
| 17 | Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double -blind, placebo-controlled trial. (15132403) | Goldberg A.C.... Mitchel Y.B. | 2004 | APOB |
| 18 | Endogenous opioids, mu-opiate receptors and chloroquine-induced pruritus: a double-blind comparison of naltrexone and promethazine in patients with malaria fever who have an established history of generalized chloroquine-induced itching. (15569037) | Ajayi A.A.... Udoh S.J. | 2004 | OPRM1 |
| 19 | Effectiveness of salmon calcitonin nasal spray in the treatment of lumbar canal stenosis: a double-blind, randomized, placebo-controlled, parallel group trial. (15507793) | Podichetty V.K.... Mazanec D.J. | 2004 | CALCA |
| 20 | Circadian genes in a blind subterranean mammal III: molecular cloning and circadian regulation of cryptochrome genes in the blind subterranean mole rat, Spalax ehrenbergi superspecies. (14964701) | Avivi A.... Nevo E. | 2004 | CRY1 |
| 21 | Comparison of fluvastatin + fenofibrate combination therapy and fluvastatin monotherapy in the treatment of combined hyperlipidemia, type 2 diabetes mellitus, and coronary heart disease: a 12-month, randomized, double-blind, controlled trial. (15598476) | Derosa G.... Roggeri D.E. | 2004 | COG2 |
| 22 | The effect of mifepristone on the expression of steroid hormone receptors in human decidua and placenta: a randomized placebo-controlled double-blind study. (14671179) | Chan C.C.... Cheung A.N. | 2003 | PGR, ESR1, NR3C1 |
| 23 | The potent somatostatin analogue vapreotide does not decrease pancreas-specific complications after elective pancreatectomy: a prospective, multicenter, double-blinded, randomized, placebo-controlled trial. (12691930) | Sarr M.G. | 2003 | SST |
| 24 | Vasopressin V2-receptor blockade with tolvaptan in patients with chronic heart failure: results from a double-blind, randomized trial. (12742979) | Gheorghiade M.... Orlandi C. | 2003 | AVPR2 |
| 25 | A randomized, double-blind, controlled, parallel-group comparison of perindopril and candesartan in hypertensive patients with type 2 diabetes mellitus. (12946547) | Derosa G.... Fogari R. | 2003 | SERPINE1, ALB |
| 26 | A double-blind randomized trial: prophylactic vasopressin reduces hypotension after cardiopulmonary bypass. (12645718) | Morales D.L.... Oz M.C. | 2003 | ACE |
| 27 | Phase II, randomized, double-blind study of two dose levels of arzoxifene in patients with locally advanced or metastatic breast can cer. (12637464) | Buzdar A.... Hudis C. | 2003 | ESR1 |
| 28 | Double-blind randomised trial comparing the non-stero idal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer. (12488294) | Tominaga T.... Ohashi Y. | 2003 | CYP19A1 |
| 29 | Clinical, metabolic and endocrine parameters in response to metformin in obese women with polycystic ovary syndrome: a randomized, double-blind and placebo-controlled trial. (12734787) | Chou K.H.... Spritzer P.M. | 2003 | SHBG |
| 30 | A randomized, blinded trial comparing the hemostatic effects of pentastarch versus hetastarch. (11896309) | Strauss R.G.... Stump D.C. | 2002 | F8 |
| 31 | A double-blind, randomized comparison of intramuscula rly and intravenously administered parecoxib sodium versus ketorolac and placeb o in a post-oral surgery pain model. (11519767) | Daniels S.E.... Hubbard R.C. | 2001 | PTGS2 |
| 32 | Responder characteristics to a single oral dose of ch olinesterase inhibitor: a double-blind placebo-controlled study with tacrine in Alzheimer patients. (11125238) | Almkvist O.... Nordberg A. | 2001 | ACHE |
| 33 | A double-blind placebo-controlled study of an infusion of lexipafant (Platelet-activating factor receptor antagonist) in patients with severe sepsis. (10681340) | Suputtamongkol Y.... White N.J. | 2000 | PTAFR |
| 34 | Short-chain fatty acid enemas stimulate plasminogen activator inhibitor-1 after abdominal aortic graft surgery: a double-blinded, placebo-controlled study. (10828475) | Mortensen F.V.... Hessov I. | 2000 | SERPINE1 |
| 35 | Effect of the serotonin receptor agonist, buspirone, on immune function in HIV-infected individuals: a six-month randomized, double-blind, placebo-controlled trial. (11590486) | Eugen-Olsen J.... Nielsen J.O. | 2000 | HTR3A |
| 36 | Randomized, placebo-controlled, double-blind, multicenter trial of efficacy and safety of granulocyte colony-stimulating factor in liver transplant recipients. (10573067) | Winston D.J.... Logan E. | 1999 | CSF3 |
| 37 | Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: results of a placebo-controlled, double-blind, pilot study. (10399774) | Asthana S.... Plymate S.R. | 1999 | IGFBP3 |
| 38 | The safety and efficacy of granulocyte-macrophage col ony-stimulating factor (Sargramostim) added to indinavir- or ritonavir-based an tiretroviral therapy: a randomized double-blind, placebo-controlled trial. (10479132) | Skowron G.... Gilbert M.J. | 1999 | IL10 |
| 39 | Effects of metformin in patients with poorly controll ed, insulin-treated type 2 diabetes mellitus. A randomized, double-blind, place bo-controlled trial. (10428734) | AvilAcs-Santa L.... Raskin P. | 1999 | INS |
| 40 | A randomized controlled double-blind study of the eff ects on hemostasis of two progestogen-only pills containing 75 microgram desoge strel or 30 microgram levonorgestrel. (9693398) | Winkler U.H.... Coelingh Bennink H.J. | 1998 | PLAT, F2 |
| 41 | Loss-of-function mutations in a calcium-channel alpha 1-subunit gene in Xp11.23 cause incomplete X-linked congenital stationary night blindness. (9662400) | Bech-Hansen N.T.... Boycott K.M. | 1998 | CACNA1F |
| 42 | Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, double-blind trials with antithrombin III in severe sepsis. (9722035) | Eisele B.... Delvos U. | 1998 | SERPINC1 |
| 43 | Double-blind placebo-controlled study of oxatomide in the treatment of childhood asthma. (9066184) | Chiu C.P.... Hsieh K.H. | 1997 | HRH1 |
| 44 | Double-blind comparison of losartan, lisinopril, and metolazone in elderly hypertensive patients with previous angiotensin-convertin g enzyme inhibitor-induced cough. (9089428) | Chan P.... Lee Y.S. | 1997 | ACE |
| 45 | Secretory phospholipase A2 as an index of disease activity in rheumatoid arthritis. Prospective double blind study of 212 patients. (8823686) | Lin M.K.... Pruzanski W. | 1996 | PLA2G2A |
| 46 | Fosinopril versus enalapril in the treatment of hyper tension: a double-blind study in 195 patients. (8797128) | Hansson L.... KjellstrAPm T. | 1996 | ACE |
| 47 | Effects of pentoxifylline on circulating cytokine concentrations and hemodynamics in patients with septic shock: results from a double-blind, randomized, placebo-controlled study. (8605790) | Zeni F.... Bertrand J.C. | 1996 | TNF, IL6, IL8 |
| 48 | A controlled double blind study of azathioprine in th e management of Crohn's disease. (8549944) | Candy S.... Goodman R. | 1995 | CRP |
| 49 | The effect of ursodeoxycholic acid on serum enzymes a nd liver histology in patients with chronic active hepatitis. A 12-month double -blind, placebo-controlled trial. (7912249) | Attili A.F.... Callea F. | 1994 | GGT1 |
| 50 | Double-blind randomized phase I study on the clinical tolerance and biological effects of natural and recombinant interferon-beta. (1431312) | Liberati A.M.... Grignani F. | 1992 | B2M, IL1A, IFNB1 |
