MCID: BLD052
MIFTS: 26

Blood Group Incompatibility

Categories: Blood diseases

Aliases & Classifications for Blood Group Incompatibility

MalaCards integrated aliases for Blood Group Incompatibility:

Name: Blood Group Incompatibility 12 51 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4176
MeSH 41 D001787
UMLS 69 C0005806

Summaries for Blood Group Incompatibility

MalaCards based summary : Blood Group Incompatibility is related to kernicterus and bilirubin metabolic disorder. An important gene associated with Blood Group Incompatibility is SLC4A1 (Solute Carrier Family 4 Member 1 (Diego Blood Group)). The drug Bilirubin has been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and kidney.

Related Diseases for Blood Group Incompatibility

Graphical network of the top 20 diseases related to Blood Group Incompatibility:



Diseases related to Blood Group Incompatibility

Symptoms & Phenotypes for Blood Group Incompatibility

Drugs & Therapeutics for Blood Group Incompatibility

Drugs for Blood Group Incompatibility (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bilirubin 635-65-4 5280352

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization Unknown status NCT00199628
2 Transcutaneous Bilirubinometers in the Community Completed NCT00735319

Search NIH Clinical Center for Blood Group Incompatibility

Cochrane evidence based reviews: blood group incompatibility

Genetic Tests for Blood Group Incompatibility

Anatomical Context for Blood Group Incompatibility

MalaCards organs/tissues related to Blood Group Incompatibility:

38
Bone, Bone Marrow, Kidney, Endothelial, Myeloid, Liver

Publications for Blood Group Incompatibility

Articles related to Blood Group Incompatibility:

(show top 50) (show all 74)
# Title Authors Year
1
ABO blood group incompatibility and infertility: still an open debate. ( 28104243 )
2017
2
Incidence and Outcome of C4d Staining With Tubulointerstitial Inflammation in Blood Group-incompatible Kidney Transplantation. ( 26151608 )
2015
3
Predictive value of cord blood bilirubin for hyperbilirubinemia in neonates at risk for maternal-fetal blood group incompatibility and hemolytic disease of the newborn. ( 26518407 )
2015
4
ABO blood group incompatibility as an adverse risk factor for outcomes in patients with myelodysplastic syndromes and acute myeloid leukemia undergoing HLA-matched peripheral blood hematopoietic cell transplantation after reduced-intensity conditioning. ( 26446051 )
2015
5
Acute kernicterus in a neonate with O/B blood group incompatibility and a mutation in SLC4A1. ( 23878048 )
2013
6
Homografts in aortic position: does blood group incompatibility have an impact on patient outcomes? ( 23390142 )
2013
7
CD144(+) endothelial microparticles as a marker of endothelial injury in neonatal ABO blood group incompatibility. ( 24333075 )
2013
8
Effect of ABO Blood Group Incompatibility on the Outcome of Single-Unit Cord Blood Transplantation after Myeloablative Conditioning. ( 24368297 )
2013
9
ABO blood group incompatibility: a diminishing barrier to successful kidney transplantation? ( 20979554 )
2010
10
Mother-child blood group incompatibility and the risk of multiple sclerosis. ( 19795153 )
2010
11
Spectrum and outcome analysis of marked neonatal hyperbilirubinemia with blood group incompatibility. ( 19664346 )
2009
12
Prevention of pure red cell aplasia after major or bidirectional ABO blood group incompatible hematopoietic stem cell transplantation by pretransplant reduction of host anti-donor isoagglutinins. ( 19144657 )
2009
13
Blood group incompatibility in kidney transplantation: definitely time to re-examine! ( 17767439 )
2007
14
ABO-histo blood group incompatibility in hematopoietic stem cell and solid organ transplantation. ( 16935028 )
2006
15
Blood group incompatibility and accelerated homograft fibrocalcifications. ( 14752436 )
2004
16
Islet cell autoantibodies in cord blood from children with blood group incompatibility or hyperbilirubinemia. ( 12820693 )
2003
17
HLA-DR11 in addition to donor age, gender, and major blood group incompatibility influence the incidence of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. ( 12826219 )
2003
18
Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. ( 11245041 )
1998
19
Combination of ABO blood group incompatibility and glucose-6-phosphate dehydrogenase deficiency: effect on hemolysis and neonatal hyperbilirubinemia. ( 9628306 )
1998
20
ABO blood group incompatibility in liver transplantation: a single-centre experience. ( 9152158 )
1997
21
Relationship between donor-recipient blood group incompatibility and serum bilirubin after allogeneic bone marrow transplantation from HLA-identical siblings. ( 7581080 )
1995
22
Differences in clinical significance of maternal-infant blood group incompatibility in mothers with blood type O, A, or B. ( 7844689 )
1995
23
Bone marrow transplantation with major ABO blood group incompatibility using automated removal of red blood cells from incompatible bone marrow by CS 3000 plus. ( 8066772 )
1994
24
Removal of maternal antibodies from a woman with repeated fetal loss due to P blood group incompatibility. ( 8073488 )
1994
25
Prevalence and lack of clinical significance of blood group incompatibility in mothers with blood type A or B. ( 8021795 )
1994
26
The clinical significance of ABO blood group incompatibility. ( 8252149 )
1993
27
Maternal-child blood group incompatibility and other perinatal events increase the risk for early-onset type 1 (insulin-dependent) diabetes mellitus. ( 1644246 )
1992
28
High-dose intravenous gammaglobulin therapy for neonatal immune haemolytic jaundice due to blood group incompatibility. ( 1709770 )
1991
29
Bone marrow transplantation in Polish conditions. Method for removal of red cells from the transplant in the case of major blood group incompatibility. ( 2639626 )
1989
30
ABO blood group incompatibility and primary tooth discoloration. ( 2639328 )
1989
31
ABO blood group incompatibility and infertility in Nigerian couples. ( 3583322 )
1987
32
Human cadaver renal transplantation in the presence of ABO blood group incompatibility. ( 3296359 )
1987
33
AB0 blood group incompatibility and inbreeding effects: evidence for an interaction. ( 3972416 )
1985
34
Familial occurrence of hemolytic disease of the newborn due to AO blood group incompatibility. ( 3972392 )
1985
35
Blood group incompatibility in bone marrow transplantation. ( 6346604 )
1983
36
Fetomaternal blood group incompatibility studies in placental intervillous thrombosis. ( 6672809 )
1983
37
Transfusion reactions in cats due to AB blood group incompatibility. ( 6635340 )
1983
38
Bone marrow transplantation with major ABO blood group incompatibility using erythrocyte depletion of marrow prior to infusion. ( 7046847 )
1982
39
Renal transplant in a patient with major donor-recipient blood group incompatibility: reversal of acute rejection by the use of modified plasmapheresis. ( 7015598 )
1981
40
ABO blood group incompatibility differentials in reproductive performance with respect to maternal age and parity among Dawoodi Bohras of Udaipur, Rajasthan. ( 7341446 )
1981
41
Current clinical concepts in hemolytic disease and blood group incompatibility. ( 6273933 )
1981
42
Current concepts in hemolytic disease and blood group incompatibility. ( 6969353 )
1980
43
Preeclampsia, neonatal asphyxia and ABO blood group incompatibility. ( 457202 )
1979
44
Blood group incompatibility and cervical hostility in relation to sterility. ( 622233 )
1978
45
Unexplained infertility and ABO blood group incompatibility. ( 1027620 )
1976
46
Significance of HLA and blood-group incompatibility in spontaneous abortion. ( 819191 )
1976
47
Practical effects of blood group incompatibility between mother and fetus. ( 4630468 )
1973
48
Blood group incompatibility between mother and foetus. ( 4114342 )
1972
49
Evaluation of a simple method for determination of IgG titre anti-A or-B in cases of possible ABO blood group incompatibility. ( 5032414 )
1972
50
Practical effects of blood group incompatibility between mother and fetus. ( 5062951 )
1972

Variations for Blood Group Incompatibility

Expression for Blood Group Incompatibility

Search GEO for disease gene expression data for Blood Group Incompatibility.

Pathways for Blood Group Incompatibility

GO Terms for Blood Group Incompatibility

Biological processes related to Blood Group Incompatibility according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 organic cation transport GO:0015695 9.16 RHCE RHD
2 ammonium transmembrane transport GO:0072488 8.96 RHCE RHD
3 ammonium transport GO:0015696 8.62 RHCE RHD

Molecular functions related to Blood Group Incompatibility according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ammonium transmembrane transporter activity GO:0008519 8.62 RHCE RHD

Sources for Blood Group Incompatibility

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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