MCID: BMP001
MIFTS: 16

Bmpr1a-Related Juvenile Polyposis malady

Genetic diseases, Gastrointestinal diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Bmpr1a-Related Juvenile Polyposis

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Bmpr1a-Related Juvenile Polyposis, Aliases & Descriptions:

Name: Bmpr1a-Related Juvenile Polyposis 20 60


Classifications:



Summaries for Bmpr1a-Related Juvenile Polyposis

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MalaCards based summary: Bmpr1a-Related Juvenile Polyposis is related to polyposis, juvenile intestinal and hereditary hemorrhagic telangiectasia. An important gene associated with Bmpr1a-Related Juvenile Polyposis is BMPR1A (bone morphogenetic protein receptor, type IA), and among its related pathways are Integrated Breast Cancer Pathway and Hippo signaling pathway. The compound threonine have been mentioned in the context of this disorder. Related mouse phenotypes are muscle and tumorigenesis.

Related Diseases for Bmpr1a-Related Juvenile Polyposis

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Diseases in the Juvenile Polyposis of Infancy family:

Smad4-Related Juvenile Polyposis bmpr1a-related juvenile polyposis

Diseases related to Bmpr1a-Related Juvenile Polyposis via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1polyposis, juvenile intestinal9.9SMAD4, BMPR1A
2hereditary hemorrhagic telangiectasia9.9BMPR1A, SMAD4
3prostate cancer9.9SMAD4, BMPR1A
4cowden disease9.8SMAD4, BMPR1A
5pancreatic cancer9.7SMAD4, BMPR1A

Graphical network of diseases related to Bmpr1a-Related Juvenile Polyposis:



Diseases related to bmpr1a-related juvenile polyposis

Symptoms for Bmpr1a-Related Juvenile Polyposis

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Drugs & Therapeutics for Bmpr1a-Related Juvenile Polyposis

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Drug clinical trials:

Search ClinicalTrials for Bmpr1a-Related Juvenile Polyposis

Search NIH Clinical Center for Bmpr1a-Related Juvenile Polyposis

Genetic Tests for Bmpr1a-Related Juvenile Polyposis

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Genetic tests related to Bmpr1a-Related Juvenile Polyposis:

id Genetic test Affiliating Genes
1 Bmpr1a-Related Juvenile Polyposis20 BMPR1A

Anatomical Context for Bmpr1a-Related Juvenile Polyposis

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Animal Models for Bmpr1a-Related Juvenile Polyposis or affiliated genes

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MGI Mouse Phenotypes related to Bmpr1a-Related Juvenile Polyposis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.1BMPR1A, SMAD4
2MP:00020068.8BMPR1A, SMAD4

Publications for Bmpr1a-Related Juvenile Polyposis

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Articles related to Bmpr1a-Related Juvenile Polyposis:

idTitleAuthorsYear
1
Vessels' morphology in SMAD4 and BMPR1A-related juvenile polyposis. (16152648)
2005

Variations for Bmpr1a-Related Juvenile Polyposis

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Expression for genes affiliated with Bmpr1a-Related Juvenile Polyposis

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Search GEO for disease gene expression data for Bmpr1a-Related Juvenile Polyposis.

Pathways for genes affiliated with Bmpr1a-Related Juvenile Polyposis

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Pathways related to Bmpr1a-Related Juvenile Polyposis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1BMPR1A, SMAD4
29.1BMPR1A, SMAD4
39.1SMAD4, BMPR1A
4
Show member pathways
9.1BMPR1A, SMAD4
5
Show member pathways
BMP receptor signaling36
BMP signalling and regulation36
BMP Signalling Pathway36
9.1BMPR1A, SMAD4
69.1BMPR1A, SMAD4

Compounds for genes affiliated with Bmpr1a-Related Juvenile Polyposis

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Sources:
43Novoseek
See all sources

Compounds related to Bmpr1a-Related Juvenile Polyposis according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1threonine439.1BMPR1A, SMAD4

GO Terms for genes affiliated with Bmpr1a-Related Juvenile Polyposis

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Biological processes related to Bmpr1a-Related Juvenile Polyposis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of SMAD protein import into nucleusGO:00603919.3BMPR1A, SMAD4
2positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.3BMPR1A, SMAD4
3developmental growthGO:00485899.2BMPR1A, SMAD4
4BMP signaling pathwayGO:00305099.2BMPR1A, SMAD4
5palate developmentGO:00600219.1SMAD4, BMPR1A
6positive regulation of transcription, DNA-templatedGO:00458939.1BMPR1A, SMAD4
7transforming growth factor beta receptor signaling pathwayGO:00071799.0BMPR1A, SMAD4
8in utero embryonic developmentGO:00017018.8BMPR1A, SMAD4

Molecular functions related to Bmpr1a-Related Juvenile Polyposis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein homodimerization activityGO:00428039.1BMPR1A, SMAD4

Products for genes affiliated with Bmpr1a-Related Juvenile Polyposis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Bmpr1a-Related Juvenile Polyposis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet