MCID: BDY001
MIFTS: 39

Body Dysmorphic Disorder malady

Categories: Mental diseases

Aliases & Classifications for Body Dysmorphic Disorder

Aliases & Descriptions for Body Dysmorphic Disorder:

Name: Body Dysmorphic Disorder 12 14
Body Dysmorphic Disorders 69
Dysmorphic Syndrome 12
Body Dysmorphia 12
Dysmorphophobia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060163

Summaries for Body Dysmorphic Disorder

Disease Ontology : 12 A somatoform disorder that involves an excessive concern about and preoccupation with a perceived defect in his or her physical features (body image).

MalaCards based summary : Body Dysmorphic Disorder, also known as body dysmorphic disorders, is related to hypoparathyroidism-retardation-dysmorphism syndrome and birk-barel mental retardation dysmorphism syndrome. An important gene associated with Body Dysmorphic Disorder is SLITRK1 (SLIT And NTRK Like Family Member 1), and among its related pathways/superpathways are Chondroitin sulfate/dermatan sulfate metabolism and mTOR signaling pathway (KEGG). The drugs Piracetam and Fluoxetine have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and skin.

Wikipedia : 71 Body dysmorphic disorder (BDD) is a mental disorder characterized by an obsessive preoccupation that... more...

Related Diseases for Body Dysmorphic Disorder

Diseases related to Body Dysmorphic Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
id Related Disease Score Top Affiliating Genes
1 hypoparathyroidism-retardation-dysmorphism syndrome 12.1
2 birk-barel mental retardation dysmorphism syndrome 12.1
3 macrocephaly, macrosomia, facial dysmorphism syndrome 11.9
4 hypoparathyroidism-intellectual disability-dysmorphism syndrome 11.8
5 intellectual disability-severe speech delay-mild dysmorphism syndrome 11.8
6 hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome 11.6
7 intellectual disability-expressive aphasia-facial dysmorphism syndrome 11.6
8 osteopenia-myopia-hearing loss-intellectual disability-facial dysmorphism syndrome 11.6
9 x-linked intellectual disability-epilepsy-progressive joint contractures-dysmorphism syndrome 11.6
10 night blindness-skeletal anomalies-dysmorphism syndrome 11.6
11 thin ribs-tubular bones-dysmorphism syndrome 11.6
12 short stature-deafness-neutrophil dysfunction-dysmorphism syndrome 11.6
13 intellectual disability-obesity-brain malformations-facial dysmorphism syndrome 11.6
14 intellectual disability-muscle weakness-short stature-facial dysmorphism syndrome 11.6
15 aids dysmorphic syndrome 11.6
16 choanal atresia-hearing loss-cardiac defects-craniofacial dysmorphism syndrome 11.6
17 microcephaly-short stature-intellectual disability-facial dysmorphism syndrome 11.6
18 med13l syndrome 10.7
19 epileptic encephalopathy, early infantile, 23 10.7
20 arachnodactyly - intellectual disability - dysmorphism 10.7
21 steel syndrome 10.5
22 dislocation of hip, congenital, with hyperextensibility of fingers and facial dysmorphism 10.5
23 epiphyseal dysplasia hearing loss dysmorphism 10.5
24 fryns macrocephaly 10.5
25 hirschsprung disease with hypoplastic nails and dysmorphic facial features 10.5
26 xia-gibbs syndrome 10.5
27 beaulieu-boycott-innes syndrome 10.5
28 tatton-brown-rahman syndrome 10.5
29 burn-mckeown syndrome 10.5
30 mental retardation, autosomal dominant 36 10.5
31 culler-jones syndrome 10.5
32 autoimmune disease, multisystem, with facial dysmorphism 10.5
33 reunion island larsen syndrome 10.5
34 mental retardation, autosomal dominant 23 10.5
35 klippel-feil syndrome 4, autosomal recessive, with myopathy and facial dysmorphism 10.5
36 kcnk9 imprinting syndrome 10.5
37 mental retardation with language impairment and with or without autistic features 10.5
38 cubitus valgus with mental retardation and unusual facies 10.5
39 spondylometaphyseal dysplasia with bowed forearms and facial dysmorphism 10.5
40 mental retardation, autosomal recessive 39 10.5
41 spinocerebellar ataxia with dysmorphism 10.5
42 cono-spondylar dysplasia 10.5
43 fibromatosis, gingival, with distinctive facies 10.5
44 noonan syndrome 3 10.5
45 atelosteogenesis ii 10.5
46 obsessive-compulsive disorder 10.4
47 eating disorder 10.2
48 anorexia nervosa 10.2
49 schizophrenia 10.0
50 delusional disorder 10.0

Graphical network of the top 20 diseases related to Body Dysmorphic Disorder:



Diseases related to Body Dysmorphic Disorder

Symptoms & Phenotypes for Body Dysmorphic Disorder

Drugs & Therapeutics for Body Dysmorphic Disorder

Drugs for Body Dysmorphic Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 77)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Piracetam Approved Phase 4 7491-74-9
2
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
3
Norepinephrine Approved Phase 4 51-41-2 439260
4 Anticonvulsants Phase 4
5 Etiracetam Phase 4
6 Neuroprotective Agents Phase 4
7 Nootropic Agents Phase 4
8 Protective Agents Phase 4,Phase 2
9 Antidepressive Agents Phase 4,Phase 3
10 Antidepressive Agents, Second-Generation Phase 4,Phase 3
11 Cytochrome P-450 CYP2D6 Inhibitors Phase 4
12 Cytochrome P-450 Enzyme Inhibitors Phase 4
13 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
14 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 2
15 Psychotropic Drugs Phase 4,Phase 3,Phase 2
16
Serotonin Phase 4,Phase 3,Phase 2 50-67-9 5202
17 Serotonin Agents Phase 4,Phase 3,Phase 2
18 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 2
19 Serotonin and Noradrenaline Reuptake Inhibitors Phase 4
20 Venlafaxine Hydrochloride Phase 4
21
Citalopram Approved Phase 3 59729-33-8 2771
22 Antiparkinson Agents Phase 3
23 Autonomic Agents Phase 3,Phase 2
24 Cholinergic Agents Phase 3
25 Cholinergic Antagonists Phase 3
26 Muscarinic Antagonists Phase 3
27 Parasympatholytics Phase 3
28 Peripheral Nervous System Agents Phase 3,Phase 2
29
Cyclosporine Approved, Investigational, Vet_approved Phase 1, Phase 2 79217-60-0, 59865-13-3 5284373 6435893
30
Fludarabine Approved Phase 1, Phase 2 21679-14-1, 75607-67-9 30751
31
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
32
Mycophenolate mofetil Approved, Investigational Phase 1, Phase 2 128794-94-5 5281078
33
Mycophenolic acid Approved Phase 1, Phase 2 24280-93-1 446541
34
Oxytocin Approved, Vet_approved Phase 2 50-56-6 439302 53477758
35
Ondansetron Approved Phase 2 99614-02-5 4595
36 Anti-Bacterial Agents Phase 1, Phase 2,Early Phase 1
37 Antibiotics, Antitubercular Phase 1, Phase 2,Early Phase 1
38 Antifungal Agents Phase 1, Phase 2
39 Anti-Infective Agents Phase 1, Phase 2,Early Phase 1
40 Antirheumatic Agents Phase 1, Phase 2
41 Calcineurin Inhibitors Phase 1, Phase 2
42 Dermatologic Agents Phase 1, Phase 2
43 Immunosuppressive Agents Phase 1, Phase 2
44 Hormone Antagonists Phase 2
45 Hormones Phase 2
46 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
47
Lactitol Phase 2 585-86-4 3871
48 Oxytocics Phase 2
49 Central Nervous System Depressants Phase 2
50 Antioxidants Phase 2

Interventional clinical trials:

(show all 34)
id Name Status NCT ID Phase
1 Effectiveness of Levetiracetam in the Treatment of Body Dysmorphic Disorder Completed NCT00265109 Phase 4
2 Fluoxetine in Pediatric Body Dysmorphic Disorder Completed NCT00245635 Phase 4
3 CBT as an Adjunct to SRIs in the Treatment of BDD Terminated NCT00211809 Phase 4
4 Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder Completed NCT00149799 Phase 3
5 Study of Patients With Body Image Issues Treated With 2 Different Behavioral Interventions Unknown status NCT01316627 Phase 2
6 Bone Marrow Transplantation in Treating Children With Sickle Cell Disease Completed NCT00004485 Phase 1, Phase 2
7 Phase II Study of Growth Hormone in Children With Cystic Fibrosis Completed NCT00016445 Phase 2
8 Oxytocin Administration in BDD and OCD Recruiting NCT02671266 Phase 2
9 Milk Thistle in Body Dysmorphic Disorder Not yet recruiting NCT02843451 Phase 2
10 Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder Terminated NCT01275248 Phase 2
11 Internet Cognitive Behavior Therapy (CBT) for Body Dysmorphic Disorder (BDD) Unknown status NCT01850433
12 Internet Delivered CBT for Body Dysmorphic Disorder Unknown status NCT02010619
13 Attentional Bias in Body Dysmorphic Disorder Completed NCT01398904
14 Treatment Study Investigating New Cognitive Behavioral Therapy Treatment Manual for Body Dysmorphic Disorder Completed NCT00106223
15 Cognitive-Behavioral Therapy for Pediatric Body Dysmorphic Disorder Completed NCT01002326
16 An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder Completed NCT01038128
17 Cognitive Behaviour Therapy (CBT) for Body Dysmorphic Disorder (BDD) Completed NCT00871143
18 Escitalopram Neuroimaging Supplement Completed NCT01398865
19 Assessment of Body Image in Patients With Rheumatoid Arthritis Completed NCT00832910
20 Effectiveness of Dance on Patients With Fibromyalgia Completed NCT00961805
21 Cortical Excitability in Obsessive-Compulsive and Related Disorders Completed NCT00029068
22 Study of the Nutritional, Metabolic, and Body Composition Profile in Children and Adolescents With Epidermolysis Bullosa Completed NCT00004791
23 Interpretation Bias Modification for Body Dysmorphic Disorder Recruiting NCT02635152
24 D-Cycloserine Augmentation of Behavior Therapy for Individuals With Body Dysmorphic Disorder Recruiting NCT00842309 Early Phase 1
25 Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder Recruiting NCT01453439
26 White Light Scanning to Aid Body Contouring: A Pilot Project Recruiting NCT01093950
27 Brain Correlates of Self-Focused Processing Recruiting NCT02808702
28 Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study Recruiting NCT02524301
29 Impairment of Central Coherence in Restrictive Anorexia Nervosa (CoCA) Recruiting NCT02381639
30 Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones Recruiting NCT03025763
31 Phenotypic and Genotypic Characterization of Subjects With Syndromic Obesity: Identifying New Candidate Genes by Exome Sequencing (OBEXOME) Recruiting NCT02510989
32 Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals Active, not recruiting NCT01075672
33 Body Image Disorder in Anorexia Nervosa and Virtual Reality Not yet recruiting NCT03118921
34 Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis Terminated NCT00014768

Search NIH Clinical Center for Body Dysmorphic Disorder

Genetic Tests for Body Dysmorphic Disorder

Anatomical Context for Body Dysmorphic Disorder

MalaCards organs/tissues related to Body Dysmorphic Disorder:

39
Brain, Eye, Skin, Breast, Testes, Bone

Publications for Body Dysmorphic Disorder

Articles related to Body Dysmorphic Disorder:

(show top 50) (show all 508)
id Title Authors Year
1
Reduced cortical thickness in body dysmorphic disorder. ( 27918913 )
2017
2
'Not just right' experiences and incompleteness in body dysmorphic disorder. ( 27918970 )
2017
3
Face and Object Perception in Body Dysmorphic Disorder versus Obsessive-Compulsive Disorder: The Mooney Faces Task. ( 28528596 )
2017
4
Visual selective attention in body dysmorphic disorder, bulimia nervosa and healthy controls. ( 27998509 )
2017
5
Cognitive-behavioral therapy for body dysmorphic disorder: A systematic review and meta-analysis of randomized controlled trials. ( 27393916 )
2016
6
Body dysmorphic disorder in different settings: A systematic review and estimated weighted prevalence. ( 27498379 )
2016
7
Cognitive dysfunction in body dysmorphic disorder: new implications for nosological systems and neurobiological models. ( 27899165 )
2016
8
Reply to: 'Body dysmorphic disorder in patients seeking abdominoplasty, rhinoplasty, and rhytidectomy'. ( 27140047 )
2016
9
Appearance evaluation of others' faces and bodies in anorexia nervosa and body dysmorphic disorder. ( 27566987 )
2016
10
Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum Reproducibly Improves Symptoms of Body Dysmorphic Disorder. ( 27743837 )
2016
11
Prevalence of Body Dysmorphic Disorder and Surgeon Diagnostic Accuracy in Facial Plastic and Oculoplastic Surgery Clinics. ( 27930752 )
2016
12
Cognitive-Behavioral Therapy for Adolescent Body Dysmorphic Disorder: A Pilot Study. ( 26956653 )
2016
13
Eumorphic Plastic Surgery: Expectation Versus Satisfaction in Body Dysmorphic Disorder. ( 27251751 )
2016
14
Prevalence and Characteristics of Body Dysmorphic Disorder Among Patients in a Partial Hospital Program. ( 27362701 )
2016
15
Intolerance of uncertainty in body dysmorphic disorder. ( 26688272 )
2016
16
Commentary on: Prevalence of Body Dysmorphic Disorder Symptoms and Body Weight Concerns in Patients Seeking Abdominoplasty. ( 26879298 )
2016
17
Body Dysmorphic Disorder in aesthetic rhinoplasty: Validating a new screening tool. ( 27223322 )
2016
18
Prevalence and correlates of body dysmorphic disorder in a community sample of adolescents. ( 27585880 )
2016
19
Cognitive-Behavioral Therapy for Body Dysmorphic Disorder by Proxy. ( 27423167 )
2016
20
Relapse Prevention and the Need for Ongoing Pharmacological Treatment in Body Dysmorphic Disorder. ( 27581691 )
2016
21
Re: "Beauty Is in the Eye of the Beholder: Body Dysmorphic Disorder in Ophthalmic Plastic and Reconstructive Surgery". ( 27608160 )
2016
22
Prevalence of Body Dysmorphic Disorder and its Association With Body Features in Female Medical Students. ( 27803720 )
2016
23
Reply re: "Beauty Is in the Eye of the Beholder: Body Dysmorphic Disorder in Ophthalmic Plastic and Reconstructive Surgery". ( 27608161 )
2016
24
Body Dysmorphic Disorder in patients undergoing septorhinoplasty surgery. Should we be performing routine screening? ( 27627585 )
2016
25
Randomised controlled trials of psychological & pharmacological treatments for body dysmorphic disorder: A systematic review. ( 27544783 )
2016
26
Training interpretation biases among individuals with body dysmorphic disorder symptoms. ( 26705744 )
2016
27
Measurement Invariance of a Body Dysmorphic Disorder Symptom Questionnaire Across Sex: The Body Image Questionnaire-Child and Adolescent Version. ( 27866170 )
2016
28
Prevalence of Body Dysmorphic Disorder and Muscle Dysmorphia Among Entry-Level Military Personnel. ( 27136659 )
2016
29
CBT delivered via internet may improve outcomes in body dysmorphic disorder. ( 26982837 )
2016
30
Relationship between self-discrepancy and worries about penis size in men with body dysmorphic disorder. ( 26952016 )
2016
31
Imagery Rescripting for Body Dysmorphic Disorder: A Multiple-Baseline Single-Case Experimental Design. ( 26956656 )
2016
32
The Body Dysmorphic Disorder Symptom Scale: Development and preliminary validation of a self-report scale of symptom specific dysfunction. ( 26971118 )
2016
33
Body Dysmorphic Disorder: Contraindication or Ethical Justification for Female Genital Cosmetic Surgery in Adolescents. ( 27717062 )
2016
34
Case report of body dysmorphic disorder in a suicidal patient. ( 27688645 )
2016
35
Pharmacotherapy Relapse Prevention in Body Dysmorphic Disorder: A Double-Blind, Placebo-Controlled Trial. ( 27056606 )
2016
36
A Case of Treatment- resistant Depression and Body Dysmorphic Disorder: The Role of Electroconvulsive Therapy Revisited. ( 27672487 )
2016
37
Anxiety and Shame as Risk Factors for Depression, Suicidality, and Functional Impairment in Body Dysmorphic Disorder and Obsessive Compulsive Disorder. ( 26998694 )
2016
38
'I will be at death's door and realize that I've wasted maybe half of my life on one body part': the experience of living with body dysmorphic disorder. ( 27314665 )
2016
39
Suicidality in body dysmorphic disorder (BDD): A systematic review with meta-analysis. ( 27607741 )
2016
40
Modifying interpretation biases in body dysmorphic disorder: Evaluation of a brief computerized treatment. ( 27664367 )
2016
41
Body dysmorphic disorder symptoms and risk for suicide: The role of depression. ( 27760403 )
2016
42
Prevalence of Body Dysmorphic Disorder Symptoms and Body Weight Concerns in Patients Seeking Abdominoplasty. ( 26851144 )
2016
43
A critical review of cosmetic treatment outcomes in body dysmorphic disorder. ( 27517118 )
2016
44
Body Dysmorphic Disorder in Patients Seeking Abdominoplasty, Rhinoplasty, and Rhytidectomy. ( 26818280 )
2016
45
Reduced striatal dopamine D2/3 receptor availability in Body Dysmorphic Disorder. ( 26711686 )
2016
46
Therapist guided internet based cognitive behavioural therapy for body dysmorphic disorder: single blind randomised controlled trial. ( 26837684 )
2016
47
Screening for Body Dysmorphic Disorder in a Dermatology Outpatient Setting at a Tertiary Care Centre. ( 27761090 )
2016
48
Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms. ( 27514293 )
2016
49
Brain connectome modularity in weight-restored anorexia nervosa and body dysmorphic disorder. ( 27429183 )
2016
50
Body dysmorphic disorder should not be considered an exclusion criterion for cosmetic surgery. ( 25456281 )
2015

Variations for Body Dysmorphic Disorder

Copy number variations for Body Dysmorphic Disorder from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 63474 12 119100000 132349534 Deletion FBXW8 dysmorphic
2 63477 12 119100000 132349534 Deletion FZD10 dysmorphic
3 63480 12 119100000 132349534 Deletion NCOR2 dysmorphic
4 63483 12 119100000 132349534 Deletion P2RX2 dysmorphic
5 63486 12 119100000 132349534 Deletion RAN dysmorphic
6 63489 12 119100000 132349534 Deletion STX2 dysmorphic
7 63492 12 119100000 132349534 Deletion TBX3 dysmorphic
8 63495 12 119100000 132349534 Deletion TESC dysmorphic
9 63498 12 119100000 132349534 Deletion ULK1 dysmorphic

Expression for Body Dysmorphic Disorder

Search GEO for disease gene expression data for Body Dysmorphic Disorder.

Pathways for Body Dysmorphic Disorder

Pathways related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.09 GPC1 GPC3 GPC6
2
Show member pathways
12.01 GPC1 GPC3 GPC6
3
Show member pathways
11.89 GPC1 GPC3 GPC6
4
Show member pathways
11.76 GPC1 GPC3 GPC6
5
Show member pathways
11.56 GPC1 GPC3 GPC6
6
Show member pathways
11.53 GPC1 GPC3 GPC6 SLC25A19
7
Show member pathways
11.3 GPC1 GPC3 GPC6

GO Terms for Body Dysmorphic Disorder

Cellular components related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 proteinaceous extracellular matrix GO:0005578 9.43 GPC1 GPC3 GPC6
2 anchored component of membrane GO:0031225 9.33 GPC1 GPC3 GPC6
3 Golgi lumen GO:0005796 9.13 GPC1 GPC3 GPC6
4 lysosomal lumen GO:0043202 8.8 GPC1 GPC3 GPC6

Biological processes related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 retinoid metabolic process GO:0001523 9.43 GPC1 GPC3 GPC6
2 glycosaminoglycan biosynthetic process GO:0006024 9.33 GPC1 GPC3 GPC6
3 glycosaminoglycan metabolic process GO:0030203 9.13 GPC1 GPC3 GPC6
4 glycosaminoglycan catabolic process GO:0006027 8.8 GPC1 GPC3 GPC6

Molecular functions related to Body Dysmorphic Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heparan sulfate proteoglycan binding GO:0043395 8.8 GPC1 GPC3 GPC6

Sources for Body Dysmorphic Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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