Aliases & Classifications for Bone Fracture

MalaCards integrated aliases for Bone Fracture:

Name: Bone Fracture 38 52

Classifications:



Summaries for Bone Fracture

MalaCards based summary : Bone Fracture is related to brain injury and spinal muscular atrophy with congenital bone fractures 1. An important gene associated with Bone Fracture is STAT3 (Signal Transducer And Activator Of Transcription 3), and among its related pathways/superpathways are GPCR Pathway and ERK Signaling. The drugs Teriparatide and Ropivacaine have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Adipose, and related phenotypes are cardiovascular system and cellular

Wikipedia : 72 A bone fracture (sometimes abbreviated FRX or Fx, Fx, or #) is a medical condition in which there is a... more...

Related Diseases for Bone Fracture

Diseases related to Bone Fracture via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)
id Related Disease Score Top Affiliating Genes
1 brain injury 21.1 BGLAP BMP2 CAV1 CRP CRTAC1 FGF2
2 spinal muscular atrophy with congenital bone fractures 1 12.3
3 spinal muscular atrophy with congenital bone fractures 2 12.2
4 prenatal-onset spinal muscular atrophy with congenital bone fractures 11.9
5 antley-bixler syndrome without genital anomalies or disordered steroidogenesis 11.1
6 antley-bixler syndrome 10.9
7 nasu-hakola disease 10.9
8 hyper-ige recurrent infection syndrome 10.8
9 gnathodiaphyseal dysplasia 10.8
10 osteoporosis-pseudoglioma syndrome 10.7
11 mucolipidosis iii alpha/beta 10.7
12 multiple pterygium syndrome, lethal type 10.7
13 cerebroretinal microangiopathy with calcifications and cysts 10.7
14 neuropathy, hereditary sensory and autonomic, type vii 10.7
15 osteogenesis imperfecta, type i 10.7
16 tetanus 10.7
17 spinal muscular atrophy, x-linked 2, infantile 10.7
18 pyle disease 10.7
19 osteofibrous dysplasia 10.7
20 cerebrospinal fluid leak 10.7
21 neuropathy, hereditary sensory and autonomic, type v 10.7
22 bruck syndrome 10.7
23 mitochondrial myopathy with lactic acidosis 10.6 BGLAP BMP2 TGFB1
24 adams-oliver syndrome 5 10.5 BMP2 CRP TGFB1
25 endometrial clear cell adenocarcinoma 10.5 CRP STAT3 TLR4
26 hypoinsulinemic hypoglycemia with hemihypertrophy 10.4 BGLAP LRP5 TGFB1
27 posterior corneal pigmentation 10.4 LRP5 TLR4
28 physical disorder 10.4 BGLAP BMP2 LRP5
29 bone epithelioid hemangioma 10.4 CAV1 TGFB1
30 bone deterioration disease 10.4 BGLAP BMP2 LRP5
31 bulbospinal polio 10.4 IL2 TLR4
32 craniosynostosis 7 10.3 BMP2 CRP MYH7
33 esophagus melanoma 10.3 CRP IL2 TLR4
34 mesenchymal cell neoplasm 10.2 BGLAP CRP IL2
35 visual snow syndrome 10.2 IL2 MB
36 opportunistic bacterial infectious disease 10.2 CRP IL2 TLR4
37 vulva fibroepithelial polyp 10.2 BGLAP CRP TLR4
38 low compliance bladder 10.1 BMP2 TLR4
39 osteoporosis 10.0
40 asphyxiating thoracic dystrophy 10.0 CRP IL2 STAT3 TLR4
41 benign mammary dysplasia 10.0 CRP IL2 IL3
42 myocardium cancer 9.9 MYH7 PCOLCE
43 facial paralysis 9.9
44 detrusor sphincter dyssynergia 9.8 IL2 TGFB1 TLR4
45 fuhrmann syndrome 9.8 FGF2 NUDT6 TGFB1
46 cerebritis 9.8
47 obesity 9.7
48 lacrimal system cancer 9.7 CRP IL2 IL3
49 hepatitis 9.7
50 head injury 9.7

Graphical network of the top 20 diseases related to Bone Fracture:



Diseases related to Bone Fracture

Symptoms & Phenotypes for Bone Fracture

MGI Mouse Phenotypes related to Bone Fracture:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.18 BMP2 CAV1 CRP FGF2 IL2 LRP5
2 cellular MP:0005384 10.06 IL2 LRP5 MB STAT3 TGFB1 TGFBR3
3 hematopoietic system MP:0005397 10 STAT3 TGFB1 TGFBR3 TLR4 BMP2 CAV1
4 liver/biliary system MP:0005370 9.76 CAV1 IL2 LRP5 LTBP1 STAT3 TGFB1
5 muscle MP:0005369 9.65 STAT3 TGFB1 TGFBR3 TLR4 CAV1 FGF2
6 skeleton MP:0005390 9.32 BMP2 CAV1 FGF2 LRP5 LTBP1 PCOLCE

Drugs & Therapeutics for Bone Fracture

Drugs for Bone Fracture (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 679)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Teriparatide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 52232-67-4 16133850
2
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Phase 1 84057-95-4 71273 175805
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 50-02-2 5743
4
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 137-58-6 3676
5
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2180-92-9, 38396-39-3 2474
6
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
7
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
8
Levobupivacaine Approved Phase 4,Phase 3,Phase 2 27262-47-1 92253
9
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
10
Calcium Carbonate Approved Phase 4,Phase 3,Phase 2,Phase 1 471-34-1
11
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
12
Thrombin Approved Phase 4
13
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 57-27-2 5288826
14
Cefmetazole Approved Phase 4 56796-20-4 42008
15
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
16
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
17
Ketorolac Approved Phase 4,Phase 3 74103-06-3, 66635-83-4 3826
18
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 76-42-6 5284603
19 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1
20
Rocuronium Approved Phase 4,Phase 3 119302-91-9, 143558-00-3 441290
21
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
22
Cilostazol Approved Phase 4 73963-72-1 2754
23
Zoledronic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 118072-93-8 68740
24
Isosorbide Dinitrate Approved Phase 4 87-33-2 6883
25
Nitric Oxide Approved Phase 4,Phase 1 10102-43-9 145068
26
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 1 112809-51-5 3902
27
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
28
Ibuprofen Approved Phase 4,Phase 3,Phase 2,Early Phase 1 15687-27-1 3672
29
Etomidate Approved Phase 4 33125-97-2 36339 667484
30
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
31
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2 59467-70-8 4192
32
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 437-38-7 3345
33
Anastrozole Approved, Investigational Phase 4,Phase 3 120511-73-1 2187
34
Indapamide Approved Phase 4 26807-65-8 3702
35
Perindopril Approved Phase 4 107133-36-8, 82834-16-0 107807
36
Tramadol Approved, Investigational Phase 4,Phase 2 27203-92-5 33741
37
Desflurane Approved Phase 4 57041-67-5 42113
38
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 103-90-2 1983
39
Sevoflurane Approved, Vet_approved Phase 4,Phase 2 28523-86-6 5206
40
Dalteparin Approved Phase 4,Phase 3,Phase 2 9005-49-6
41
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
42
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 83-43-2 6741
43
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 50-24-8 5755
44
Acetylcholine Approved Phase 4,Phase 1 51-84-3 187
45
Ethanol Approved Phase 4 64-17-5 702
46
Alendronate Approved Phase 4,Phase 3,Phase 2,Phase 1 121268-17-5, 66376-36-1 2088
47
Cimetidine Approved Phase 4,Phase 2,Phase 3 51481-61-9 2756
48
Guaifenesin Approved, Vet_approved Phase 4,Early Phase 1 93-14-1 3516
49
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 22916-47-8 4189
50
Rivaroxaban Approved Phase 4,Phase 3 366789-02-8

Interventional clinical trials:

(show top 50) (show all 2702)

id Name Status NCT ID Phase Drugs
1 Treatment of Intertrochanteric Fracture With New Type of Intramedullary Nail Unknown status NCT01437176 Phase 4
2 The Use of Teriparatide as an Adjunctive Therapy for the Treatment of Jones Fractures Unknown status NCT01173081 Phase 4 Teriparatide;Placebo
3 Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture Unknown status NCT00829725 Phase 4
4 Perioperative Analgesia by Femoral Perineural Catheter for Femoral Neck Fracture - Study KTcol Unknown status NCT01052974 Phase 4 ropivacaine
5 NovaLign Intramedullary Fixation System (IFS) for the Treatment of Humeral Fractures Unknown status NCT00969839 Phase 4
6 Parathyroid Hormone for the Treatment of Humerus Fractures Unknown status NCT01687374 Phase 4 1-84 parathyroid hormone;Placebo
7 Single Dose of Dexamethasone in Femur Fractures Unknown status NCT01550146 Phase 4 Dexamethasone acetate;Placebo
8 The Effect of Liberal vs. Restrictive Transfusion Strategies on Rehabilitation After Hip Fracture Surgery Unknown status NCT00162617 Phase 4 Red blood cell transfusion
9 Outcome Comparison Between PFNA and InterTAN Unknown status NCT01797237 Phase 4
10 Hematoma Block for Reduction of Distal Radius Fractures Unknown status NCT02129270 Phase 4 Lidocaine HCl 2% .;Lidocaine HCl 1%
11 Fast Track Admittance of Hip Fracture Patients Unknown status NCT00345488 Phase 4
12 Comparing Weight Bearing After Intramedullary Fixation Devices for the Proximal Femur Fracture Unknown status NCT01509859 Phase 4
13 Dose Finding Study for Continuous Spinal Anaesthesia Unknown status NCT01680120 Phase 4
14 Efficacy and Safety of Intravenous Iron Sucrose in Patients With Hip Fracture to Prevent Perioperative Anemia Unknown status NCT01084122 Phase 4 Iron sucrose
15 Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures Unknown status NCT02580227 Phase 4 Tranexamic Acid
16 A Dose Finding Study for Pain Relief of a Broken Hip Unknown status NCT00926666 Phase 4 Levobupivacaine
17 Study of Nerve Block Anesthesia for Surgery of Hip Fracture in the Elderly Unknown status NCT02104908 Phase 4
18 Analgesic Effects of the Gastrolith, in Osteoporotic Patients Suffering From Recent Skeletal Pain Caused by Vertebral Fractures Unknown status NCT01482858 Phase 4
19 Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty Unknown status NCT01934049 Phase 4 Total Intravenous Anesthesia and Peripheral nerve blocks
20 Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel) Unknown status NCT01230931 Phase 4
21 Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw Unknown status NCT01219088 Phase 4 Bupivacaine, morphine
22 A Randomized, Double-blind Controlled Trial of Bupivacaine Extended-release Liposome Injection for Postsurgical Analgesia in Patients Undergoing Open-reduction Internal Fixation of the Distal Radius Unknown status NCT02515851 Phase 4 Exparel
23 Monopolar Electrosurgery Versus Ultrasound Scissors in Thoracoscopic Ventral Spondylodesis Unknown status NCT00941213 Phase 4
24 The Effect of Periarticular Multi-Drug Regimen on Pain After Partial Hip Replacement Unknown status NCT01112436 Phase 4 periarticular injection of multidrug regimen;none of medication preoperatively and intraoperatively
25 Deep Neuromuscular Block on Cytokines Release and Postoperative Delirium Unknown status NCT02507609 Phase 4
26 Clinical Comparison of Efficacy and Safety of Two Teriparatide Formulations: Osteofortil and Forteo Unknown status NCT01945788 Phase 4 Teriparatide (rDNA origin)
27 Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease Unknown status NCT01653600 Phase 4
28 The Effect of Zoledronic Acid to Bone Fusion and Bone Metabolism of Patients With Lumbar Degenerative Disease After Lumbar Interbody Fusion Unknown status NCT01310465 Phase 4 zoledronic acid;sodium chloride
29 Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes Mellitus Unknown status NCT02011620 Phase 4
30 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4 Letrozole
31 Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) Unknown status NCT01822106 Phase 4
32 Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients Unknown status NCT02152163 Phase 4 IV Ibuprofen;placebo
33 Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children Unknown status NCT02013986 Phase 4 etomidate;midazolam;propofol
34 Bone Turnover in Type 2 Diabetes Patients Unknown status NCT00732121 Phase 4 Sitagliptin;Placebo
35 Role of Stress Reduction Protocol on Outcome of Periodontal Therapy Unknown status NCT02487862 Phase 4
36 Manually Versus Digitally Fabricated Removable Partial Dentures Unknown status NCT01191073 Phase 4
37 Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC Unknown status NCT01795794 Phase 4 omeprazole
38 Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients Unknown status NCT00912938 Phase 4 zoledronic acid
39 Intranasal Fentanyl for Pain Management Unknown status NCT00882960 Phase 4 intravenous fentanyl;intra-nasal fentanyl
40 Changes in Knee Articular Cartilage Volume in Women on Aromatase Inhibitors Unknown status NCT00111241 Phase 4 aromatase inhibitors (letrozole, anastrozole)
41 The Hypertension in the Very Elderly Trial (HYVET) Unknown status NCT00122811 Phase 4 Indapamide SR 1.5mg; Perindopril 2-4mg
42 Drug Eluting Ballon Versus Stenting in the Superficial Femoral Artery Unknown status NCT02212470 Phase 4
43 Study Evaluating InductOs in Diaphyseal Tibia Fractures Completed NCT00161616 Phase 4 InductOs
44 Efficacy of DBM on Fractures of the Shinbone (Tibia) Completed NCT00299052 Phase 4
45 Allomatrix Injectable Putty in Distal Radius Fractures Completed NCT00274378 Phase 4
46 Evaluation of the Effects of Less Invasive Stabilization System (LISS) Plating Techniques in Distal Femoral Fractures Completed NCT00552331 Phase 4
47 RCT on Ketorolac and Tramadol in Bone Fractures Pain of Child Completed NCT00560443 Phase 4 ketorolac;tramadol
48 Treatment of Acetabular Posterior Wall Fracture With Anatomical Locking Plate Completed NCT01437150 Phase 4
49 Outcomes of Operative Treatment of Unstable Ankle Fracture - Comparison Between Metallic and Biodegradable Implants Completed NCT01431560 Phase 4
50 Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture Completed NCT00824564 Phase 4 Tranexamic Acid plus standard of care

Search NIH Clinical Center for Bone Fracture

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Bone Fracture cell therapies at LifeMap Discovery.

Genetic Tests for Bone Fracture

Anatomical Context for Bone Fracture

MalaCards organs/tissues related to Bone Fracture:

39
Bone, Breast, Prostate, Bone Marrow, Kidney, Spinal Cord, Testes
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Bone Fracture:
id Tissue Anatomical CompartmentCell Relevance
1 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
2 Adipose Subcutaneous White Adipose Stromal Cells Potential therapeutic candidate

Publications for Bone Fracture

Articles related to Bone Fracture:

(show top 50) (show all 670)
id Title Authors Year
1
Bone fracture risk in patients with rheumatoid arthritis: A meta-analysis. ( 28885321 )
2017
2
Improving the human-robot interface for telemanipulated robotic long bone fracture reduction: Joystick device vs. haptic manipulator. ( 28948678 )
2017
3
Delayed Expression of Circulating TGF-I^1 and BMP-2 Levels in Human Nonunion Long Bone Fracture Healing. ( 28331138 )
2017
4
Osthole Promotes Bone Fracture Healing through Activation of BMP Signaling in Chondrocytes. ( 28924381 )
2017
5
Convex bone deformity after closed reduction of nasal bone fracture. ( 28918998 )
2017
6
Olfactory Dysfunction in Nasal Bone Fracture. ( 28913314 )
2017
7
Customized titanium mesh based on the 3D printed model vs. manual intraoperative bending of titanium mesh for reconstructing of orbital bone fracture: a randomized clinical trial. ( 28828975 )
2017
8
Factors related to infection after fixation in the process of late healed bone fracture. ( 28810567 )
2017
9
Spinal Reorganization after Bone Fracture in Mice. ( 28062308 )
2017
10
The Algorithm-Oriented Management of Nasal Bone Fracture according to Stranc's Classification System. ( 28913315 )
2017
11
Bone fracture nonunion rate decreases with increasing age: A prospective inception cohort study. ( 27836732 )
2017
12
A review of computational models of bone fracture healing. ( 28785849 )
2017
13
Regenerate bone fracture rate following femoral lengthening in paediatric patients. ( 28828065 )
2017
14
Correlation between Operation Result and Patient Satisfaction of Nasal Bone Fracture. ( 28913299 )
2017
15
Mast Cells Are Critical Regulators of Bone Fracture-Induced Inflammation and Osteoclast Formation and Activity. ( 28777474 )
2017
16
Study of fall risk-increasing drugs in elderly patients before and after a bone fracture. ( 28916557 )
2017
17
STAT3 promotes bone fracture healing by enhancing the FOXP3 expression and the suppressive function of regulatory T cells. ( 28493494 )
2017
18
In vivo study of microarc oxidation coated biodegradable magnesium plate to heal bone fracture defect of 3mm width. ( 28688364 )
2017
19
An Algorithmic Approach Using Ultrasonography in the Diagnosis of Pediatric Nasal Bone Fracture. ( 27906845 )
2017
20
Impairment of cold injury-induced muscle regeneration in mice receiving a combination of bone fracture and alendronate treatment. ( 28715470 )
2017
21
The role of impairment of mesenchymal stem cell function in osteoporotic bone fracture healing. ( 28677081 )
2017
22
Occurrence of Clinical Bone Fracture Following a Prolonged Stay in Intensive Care Unit: A Retrospective Controlled Study. ( 28695239 )
2017
23
Objective Outcomes of Closed Reduction According to the Type of Nasal Bone Fracture. ( 28913300 )
2017
24
Anti-IL-20 monoclonal antibody promotes bone fracture healing through regulating IL-20-mediated osteoblastogenesis. ( 27075747 )
2016
25
The impact velocity and bone fracture pattern: Forensic perspective. ( 27220089 )
2016
26
Association of Respiratory Tuberculosis with Incident Bone Fracture: Bridging the Tuberculosis Airway Infection and the Osteoporotic Bone. ( 28005963 )
2016
27
Bone: Fracture risk after bariatric surgery. ( 27516344 )
2016
28
Larynx Trauma and Hyoid Bone Fracture after Bite Injury in Dog: Case Report. ( 27579303 )
2016
29
Long-term response of femoral density to hip implant and bone fracture plate: Computational study using a mechano-biochemical model. ( 26751582 )
2016
30
Reevaluating the Utility of Maxillary Sinus Opacification as a Screening Tool for Facial Bone Fracture a Decade After Its Original Analysis. ( 27014521 )
2016
31
Audiologic Patterns of Otic Capsule Preserving Temporal Bone Fracture: Effects of the Affected Subsites. ( 27337953 )
2016
32
Biomechanical Studies on Patterns of Cranial Bone Fracture Using the Immature Porcine Model. ( 27537363 )
2016
33
Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation. ( 27955656 )
2016
34
Postoperative Satisfaction in Nasal Bone Fracture Patients Who Had Rhinoplasty. ( 27748725 )
2016
35
Bilateral Facial Paralysis Caused by Temporal Bone Fracture: A Case Report. ( 27679786 )
2016
36
Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures. ( 26924529 )
2016
37
Investigation of the mechanical properties and failure modes of hybrid natural fiber composites for potential bone fracture fixation plates. ( 27618754 )
2016
38
Hyoid Bone Fracture: Associated With Head and Neck Trauma-A Rare Case Report. ( 27408446 )
2016
39
Cortical bone fracture analysis using XFEM - case study. ( 27287280 )
2016
40
Epihyoid bone fracture associated with tongue deviation in an adult dog. ( 27587884 )
2016
41
Contralateral Cochlear Labyrinthine Concussion without Temporal Bone Fracture: Unusual Posttraumatic Consequence. ( 27738540 )
2016
42
Computer assisted preoperative planning of bone fracture reduction: Simulation techniques and new trends. ( 26849422 )
2016
43
Abducens Nerve Avulsion and Facial Nerve Palsy After Temporal Bone Fracture: A Rare Concomitance of Injuries. ( 26723286 )
2016
44
A leg up on bone-fracture healing. ( 27654673 )
2016
45
Immature myeloid cells are critical for enhancing bone fracture healing through angiogenic cascade. ( 27664567 )
2016
46
Surface Reconstruction from Parallel Curves with Application to Parietal Bone Fracture Reconstruction. ( 26967643 )
2016
47
Elevated D-dimer and fibrinogen levels in serum of preoperative bone fracture patients. ( 27026858 )
2016
48
Bone fracture healing is delayed in splenectomic rats. ( 27956350 )
2016
49
Sport Practice And Occurrence Of Bone Fracture In Adolescents During 9-months Of Follow-up: 2090 Board #242 June 2, 2: 00 PM - 3: 30 PM. ( 27360915 )
2016
50
Modelling of bone fracture and strength at different length scales: a review. ( 26855749 )
2016

Variations for Bone Fracture

Expression for Bone Fracture

Search GEO for disease gene expression data for Bone Fracture.

Pathways for Bone Fracture

Pathways related to Bone Fracture according to GeneCards Suite gene sharing:

(show all 37)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.67 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
2
Show member pathways
13.65 BMP2 FGF2 IL2 IL3 LRP5 LTBP1
3
Show member pathways
13.49 BMP2 CRP FGF2 IL2 IL3 LTBP1
4
Show member pathways
13.47 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
5
Show member pathways
13.26 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
6
Show member pathways
13.24 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
7
Show member pathways
13.16 BMP2 CAV1 FGF2 IL2 IL3 LTBP1
8
Show member pathways
13.02 BMP2 FGF2 IL2 IL3 LTBP1 MYH2
9
Show member pathways
12.81 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
10
Show member pathways
12.79 CAV1 IL2 IL3 MYH7 TGFB1
11
Show member pathways
12.68 BMP2 FGF2 LTBP1 PCOLCE TGFB1
12
Show member pathways
12.49 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
13
Show member pathways
12.41 BMP2 FGF2 MYH7 TGFB1
14 12.14 LRP5 STAT3 TGFB1 TLR4
15 12.14 CAV1 FGF2 STAT3 TGFB1 TLR4
16
Show member pathways
12.1 FGF2 LRP5 STAT3 TGFB1
17 12 FGF2 IL3 STAT3 TGFB1
18 11.87 BMP2 IL3 TGFB1
19
Show member pathways
11.85 IL2 STAT3 TGFB1 TLR4
20
Show member pathways
11.84 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
21 11.81 IL2 TGFB1 TLR4
22
Show member pathways
11.81 STAT3 TGFB1 TLR4
23
Show member pathways
11.79 STAT3 TGFB1 TGFBR3 TLR4
24 11.78 BGLAP BMP2 FGF2 TGFB1
25 11.77 FGF2 TGFB1 TGFBR3
26 11.75 BMP2 LTBP1 TGFB1
27 11.68 LRP5 TGFB1 TLR4
28
Show member pathways
11.67 BMP2 LTBP1 TGFB1
29 11.51 CAV1 TGFB1 TGFBR3
30 11.48 FGF2 TGFB1 TGFBR3
31 11.46 FGF2 IL3 TGFB1
32 11.43 LTBP1 STAT3 TGFB1 TGFBR3
33 11.41 BGLAP STAT3 TGFB1
34 11.39 BMP2 FGF2 IL2 IL3 LTBP1 NUDT6
35 11.2 IL2 IL3 TGFB1
36 11.16 IL2 STAT3 TGFB1

GO Terms for Bone Fracture

Cellular components related to Bone Fracture according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 BGLAP BMP2 CRP CRTAC1 FGF2 IL2
2 extracellular space GO:0005615 9.32 BGLAP BMP2 CRP FGF2 IL2 IL3

Biological processes related to Bone Fracture according to GeneCards Suite gene sharing:

(show all 27)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.88 BMP2 CRP STAT3 TGFB1 TLR4
2 positive regulation of cell proliferation GO:0008284 9.88 FGF2 IL2 IL3 LRP5 STAT3 TGFB1
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.83 BMP2 FGF2 TGFB1 TLR4
4 BMP signaling pathway GO:0030509 9.78 BMP2 TGFB1 TGFBR3
5 MAPK cascade GO:0000165 9.77 CAV1 FGF2 IL2 IL3 TGFB1
6 cellular response to organic cyclic compound GO:0071407 9.74 BMP2 STAT3 TGFB1
7 negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 9.73 CAV1 TGFB1 TGFBR3
8 somatic stem cell population maintenance GO:0035019 9.71 FGF2 LRP5 STAT3
9 cellular response to growth factor stimulus GO:0071363 9.69 BGLAP BMP2 TGFB1
10 hyaluronan catabolic process GO:0030214 9.63 FGF2 TGFB1
11 positive regulation of gene expression GO:0010628 9.63 BMP2 CAV1 CRP STAT3 TGFB1 TLR4
12 cardiac epithelial to mesenchymal transition GO:0060317 9.62 BMP2 TGFBR3
13 positive regulation of interleukin-17 production GO:0032740 9.62 IL2 TGFB1
14 positive regulation of peptidase activity GO:0010952 9.61 CAV1 PCOLCE
15 epithelial to mesenchymal transition GO:0001837 9.61 BMP2 TGFB1 TGFBR3
16 positive regulation of superoxide anion generation GO:0032930 9.6 CRP TGFB1
17 positive regulation of osteoblast proliferation GO:0033690 9.59 BMP2 LRP5
18 negative regulation of interleukin-17 production GO:0032700 9.58 TGFB1 TLR4
19 positive regulation of regulatory T cell differentiation GO:0045591 9.58 IL2 TGFB1
20 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.55 IL2 IL3
21 ventricular cardiac muscle tissue morphogenesis GO:0055010 9.5 MYH7 TGFB1 TGFBR3
22 positive regulation of odontogenesis GO:0042482 9.46 BMP2 TGFB1
23 positive regulation of pri-miRNA transcription from RNA polymerase II promoter GO:1902895 9.43 BMP2 STAT3 TGFB1
24 response to hypoxia GO:0001666 9.35 BMP2 CAV1 MB TGFB1 TGFBR3
25 regulation of regulatory T cell differentiation GO:0045589 9.33 TGFB1
26 pathway-restricted SMAD protein phosphorylation GO:0060389 8.8 BMP2 TGFB1 TGFBR3
27 positive regulation of transcription from RNA polymerase II promoter GO:0045944 10.04 BMP2 FGF2 IL2 LRP5 STAT3 TGFB1

Molecular functions related to Bone Fracture according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peptidase activator activity GO:0016504 9.37 CAV1 PCOLCE
2 cytokine activity GO:0005125 9.35 BMP2 FGF2 IL2 IL3 TGFB1
3 transforming growth factor beta receptor binding GO:0005160 9.33 BMP2 TGFB1 TGFBR3
4 type II transforming growth factor beta receptor binding GO:0005114 9.32 TGFB1 TGFBR3
5 transforming growth factor beta-activated receptor activity GO:0005024 9.26 LTBP1 TGFBR3
6 growth factor activity GO:0008083 9.1 BMP2 FGF2 IL2 IL3 NUDT6 TGFB1

Sources for Bone Fracture

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
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37 KEGG
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59 PubMed
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65 SNOMED-CT via HPO
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67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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