MCID: BTR001
MIFTS: 39

Botryoid Rhabdomyosarcoma malady

Rare diseases, Cancer diseases categories

Aliases & Classifications for Botryoid Rhabdomyosarcoma

About this section

Botryoid Rhabdomyosarcoma, Aliases & Descriptions:

Name: Botryoid Rhabdomyosarcoma 9 60
Sarcoma Botryoides 9 41
 
Botryoid Sarcoma 9 60
Botryoid-Type Embryonal Rhabdomyosarcoma 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


External Ids:

Disease Ontology9 DOID:3255
NCIt38 C9150

Summaries for Botryoid Rhabdomyosarcoma

About this section


Wikipedia:63 Sarcoma botryoides or botryoid sarcoma or botryoid rhabdomyosarcoma is a subtype of embryonal... more...

MalaCards based summary: Botryoid Rhabdomyosarcoma, also known as sarcoma botryoides, is related to rhabdomyosarcoma and embryonal rhabdomyosarcoma. An important gene associated with Botryoid Rhabdomyosarcoma is ACTC1 (actin, alpha, cardiac muscle 1), and among its related pathways are Hypertrophic cardiomyopathy (HCM) and Striated Muscle Contraction. The compounds orcein and s 100 have been mentioned in the context of this disorder. Affiliated tissues include uterus and cervix, and related mouse phenotypes are cardiovascular system and normal.

Related Diseases for Botryoid Rhabdomyosarcoma

About this section

Diseases in the Botryoid Rhabdomyosarcoma family:

Adult Botryoid Rhabdomyosarcoma

Diseases related to Botryoid Rhabdomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1rhabdomyosarcoma30.6DES, MYOD1, MYOG, ACTC1, WT1
2embryonal rhabdomyosarcoma29.7WT1, ACTC1, MYOG, MYOD1, DES
3wilms tumor29.5DES, MYOD1, MYOG, ACTC1, WT1
4sarcoma29.5WT1, ACTC1, MYOG, MYOD1, DES
5alveolar soft-part sarcoma10.5MYOD1
6adult botryoid rhabdomyosarcoma10.4
7adult vagina botryoid rhabdomyosarcoma10.4
8childhood botryoid rhabdomyosarcoma10.4
9childhood vagina botryoid rhabdomyosarcoma10.4
10vagina botryoid rhabdomyosarcoma10.4
11fasciitis10.4ACTC1
12cervicitis10.4
13infantile myofibromatosis10.4DES
14sertoli-leydig cell tumor10.3
15leydig cell tumor10.3
16metanephric adenoma10.3WT1
17malignant mesenchymoma10.3MYOD1, MYOG
18adenomatoid tumor10.3WT1
19neuroectodermal tumor10.2
20choledochal cyst10.2
21gallbladder sarcoma10.2
22laryngitis10.2
23pleomorphic rhabdomyosarcoma10.2
24myotonic dystrophy10.2MYOG, MYOD1
25myoma10.2DES, MYOG
26vulvar childhood botryoid-type embryonal rhabdomyosarcoma10.2
27bladder sarcoma10.2
28vagina sarcoma10.2
29vaginitis10.2
30adenosarcoma10.2ACTC1, DES
31epithelioid leiomyosarcoma10.2DES, ACTC1
32angiosarcoma10.2KRT18, ACTC1
33spindle cell carcinoma10.1ACTC1, DES
34spindle cell sarcoma10.1ACTC1, DES
35desmoid disease, hereditary10.1DES, ACTC1
36myopathy congenital10.1DES, MYOG
37cutaneous fibrous histiocytoma10.1DES, ACTC1
38fibrous histiocytoma10.1ACTC1, DES
39dermatofibrosarcoma protuberans10.1ACTC1, DES
40endometrial stromal sarcoma10.1DES, ACTC1
41duchenne muscular dystrophy10.1MYOD1, DES
42hemangiopericytoma10.1DES, ACTC1
43angiomyolipoma10.1ACTC1, DES
44glomus tumor10.1DES, ACTC1
45fibroma10.1DES, ACTC1
46malignant mixed mullerian tumor10.1DES, ACTC1
47uterine fibroid10.1DES, MYOG
48fibromatosis10.1ACTC1, DES
49chordoma10.1DES, KRT18
50smooth muscle tumor10.1ACTC1, DES

Graphical network of the top 20 diseases related to Botryoid Rhabdomyosarcoma:



Diseases related to botryoid rhabdomyosarcoma

Symptoms for Botryoid Rhabdomyosarcoma

About this section

Drugs & Therapeutics for Botryoid Rhabdomyosarcoma

About this section

Drug clinical trials:

Search ClinicalTrials for Botryoid Rhabdomyosarcoma

Search NIH Clinical Center for Botryoid Rhabdomyosarcoma

Genetic Tests for Botryoid Rhabdomyosarcoma

About this section

Anatomical Context for Botryoid Rhabdomyosarcoma

About this section

MalaCards organs/tissues related to Botryoid Rhabdomyosarcoma:

31
Uterus, Cervix

Animal Models for Botryoid Rhabdomyosarcoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Botryoid Rhabdomyosarcoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.3WT1, ACTC1, MYOD1, DES
2MP:00028737.9MYOD1, MYOG, ACTC1, WT1
3MP:00053697.9WT1, ACTC1, MYOG, MYOD1, DES
4MP:00053767.6WT1, ACTC1, MYOG, MYOD1, DES
5MP:00053787.6MYOD1, MYOG, ACTC1, KRT18, WT1
6MP:00107687.2DES, MYOD1, MYOG, ACTC1, KRT18, WT1

Publications for Botryoid Rhabdomyosarcoma

About this section

Articles related to Botryoid Rhabdomyosarcoma:

(show all 35)
idTitleAuthorsYear
1
A botryoid rhabdomyosarcoma diagnosed as a choledochal cyst. (23832499)
2013
2
Embryonal (botryoides) rhabdomyosarcoma of the uterus harboring a primitive neuroectodermal tumor component. (22653355)
2012
3
Massive diffuse intraperitoneal multicystic mass in an infant. Botryoid rhabdomyosarcoma (RMS). (22421724)
2012
4
Botryoid rhabdomyosarcoma of the uterine cervix. (22943732)
2012
5
Primary gallbladder sarcoma: a clinicopathologic study of 15 cases, heterogeneous sarcomas with poor outcome, except pediatric botryoid rhabdomyosarcoma. (19194282)
2009
6
Urinary bladder botryoid rhabdomyosarcoma with widespread metastases in an 8-month-old Labrador cross dog. (20169756)
2009
7
Primary renal botryoid rhabdomyosarcoma: diagnosis and outcome. (18082685)
2007
8
Right atrial botryoid rhabdomyosarcoma in an adult patient with recurrent pleomorphic rhabdomyosarcomas following doxorubicin therapy. (17630111)
2007
9
Botryoid rhabdomyosarcoma of the biliary tract in children: a unique case report. (17177904)
2006
10
Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. (16220232)
2005
11
Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. (16010486)
2005
12
Botryoid rhabdomyosarcoma of vagina--two case reports. (15887839)
2004
13
Botryoid rhabdomyosarcoma of common bile duct. (15107524)
2004
14
Urinary Bladder Botryoid Rhabdomyosarcoma with Immature Cartilage in a 24-year-old Male Patient: A Case Report. (17657126)
2003
15
Botryoid rhabdomyosarcoma of mesentery--a case report. (15025305)
2003
16
Embryonal botryoid rhabdomyosarcoma of the bladder]. (12410104)
2002
17
Botryoid rhabdomyosarcoma of the bladder in an adult female. (17955586)
2002
18
Isochromosome (17)(q10) as the sole structural chromosomal rearrangement in a case of botryoid rhabdomyosarcoma. (11454423)
2001
19
Botryoid rhabdomyosarcoma of the nose: pitfalls of pathology. (11359096)
2001
20
Cytogenetic abnormalities in a case of botryoid rhabdomyosarcoma. (10742076)
2000
21
Botryoid rhabdomyosarcoma of the bladder. (9338741)
1997
22
Unique dermal and subcutaneous botryoid rhabdomyosarcoma associated with mature renal tissue: is this an extrarenal Wilms' tumor? (7971581)
1994
23
Cytogenetic study of botryoid rhabdomyosarcoma of the uterine cervix. (8438559)
1993
24
Botryoid rhabdomyosarcoma of the urinary bladder in a filly. (8373864)
1993
25
Computed tomography in botryoid rhabdomyosarcoma of urinary bladder. (2346927)
1990
26
Laryngeal botryoid rhabdomyosarcoma in an adult. Report of a case with electron microscopic study. (2780434)
1989
27
Embryonal botryoid rhabdomyosarcoma of the mitral valve. (3946244)
1986
28
Botryoid rhabdomyosarcoma of the nasopharynx. (6864097)
1983
29
Botryoid rhabdomyosarcoma of the gallbladder in a child. (7055789)
1982
30
Botryoid rhabdomyosarcoma in the urinary bladder of a dog. (7281468)
1981
31
Botryoid rhabdomyosarcoma of the biliary tract. (7337157)
1981
32
Botryoid rhabdomyosarcoma of the uterus of a filly. (7400023)
1980
33
Botryoid rhabdomyosarcoma of the urinary bladder and hypertrophic osteoarthropathy in a young dog. (4473190)
1974
34
Nasal botryoid rhabdomyosarcoma. (5040563)
1972
35
Botryoid rhabdomyosarcoma of the urinary bladder of a dog. (5693155)
1968

Variations for Botryoid Rhabdomyosarcoma

About this section

Expression for genes affiliated with Botryoid Rhabdomyosarcoma

About this section
Search GEO for disease gene expression data for Botryoid Rhabdomyosarcoma.

Pathways for genes affiliated with Botryoid Rhabdomyosarcoma

About this section

Pathways related to Botryoid Rhabdomyosarcoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy36
9.6ACTC1, DES
2
Show member pathways
9.6DES, ACTC1
3
Show member pathways
Neurophysiological process Receptor mediated axon growth repulsion58
Pathogenic Escherichia coli infection36
Cytoskeleton remodeling Slit Robo signaling
9.4KRT18, ACTC1
4
Show member pathways
9.1MYOG, MYOD1
5
Show member pathways
Development Role of HDAC and calcium calmodulin dependent kinase CaMK in control of skeletal myogenesis58
9.1MYOG, MYOD1
69.1MYOG, MYOD1
79.0KRT18, ACTC1, DES

Compounds for genes affiliated with Botryoid Rhabdomyosarcoma

About this section

Compounds related to Botryoid Rhabdomyosarcoma according to GeneCards Suite gene sharing:

(show all 50)
idCompoundScoreTop Affiliating Genes
1orcein4310.0ACTC1, DES
2s 1004310.0ACTC1, DES
3reticulin4310.0ACTC1, DES
4mucicarmine4310.0ACTC1, DES
5procollagen439.9DES, ACTC1
6nash439.8ACTC1, KRT18
7biotin43 24 1211.8ACTC1, DES
8tetracycline43 1210.6WT1, KRT18
9b 723439.5DES, ACTC1, WT1
10imatinib43 49 1211.5WT1, ACTC1, DES
11p002439.5DES, KRT18
12hematoxylin439.4KRT18, ACTC1, DES
13azathioprine43 2 49 1212.4DES, MYOD1
14formaldehyde43 2410.4DES, ACTC1, KRT18
15ribonucleic acid439.4WT1, ACTC1, MYOG
16glycogen43 2410.3DES, ACTC1, KRT18
17gold439.3DES, KRT18
18iron43 2410.3KRT18, ACTC1, DES
19lactacystin439.3MYOD1, KRT18
20doxorubicin43 49 1211.2WT1, KRT18, DES
21thymidine43 2410.1WT1, KRT18, DES
22forskolin43 49 1211.1MYOG, KRT18, WT1
23mg 13243 5910.0KRT18, MYOD1
24acetylcholine43 49 28 24 1213.0MYOG, MYOD1, DES
25lysine439.0DES, MYOD1, WT1
26actinomycin d438.9KRT18, MYOD1, DES
27progesterone43 28 59 24 1212.9DES, ACTC1, KRT18, WT1
28arginine438.8DES, MYOD1, WT1
29citrate438.7KRT18, MYOD1
30nitric oxide43 24 1210.7DES, MYOG, KRT18, WT1
31zinc43 249.6WT1, KRT18, MYOD1
3212-o-tetradecanoylphorbol 13-acetate438.6WT1, MYOG, MYOD1, DES
33cysteine438.5DES, MYOD1, MYOG, WT1
34bromodeoxyuridine438.5DES, MYOD1, MYOG, KRT18
35fatty acid438.5DES, MYOD1, MYOG, KRT18
36threonine438.4DES, MYOD1, KRT18, WT1
37butyrate438.4MYOD1, MYOG, KRT18, WT1
38oligonucleotide438.4WT1, KRT18, MYOG, MYOD1
39calcium43 49 24 1211.3ACTC1, MYOG, MYOD1, DES
40oxygen43 249.1DES, MYOD1, MYOG, ACTC1, KRT18
41glucose438.1DES, MYOD1, MYOG, ACTC1, KRT18
42serine437.9DES, MYOD1, MYOG, KRT18, WT1
43paraffin437.6WT1, KRT18, ACTC1, MYOG, MYOD1, DES
44creatinine437.6DES, MYOD1, MYOG, ACTC1, KRT18, WT1
45testosterone43 59 24 1210.6DES, MYOD1, MYOG, ACTC1, KRT18, WT1
46steroid437.6DES, MYOD1, MYOG, ACTC1, KRT18, WT1
47vegf437.6DES, MYOD1, MYOG, ACTC1, KRT18, WT1
48estrogen437.6DES, MYOD1, MYOG, ACTC1, KRT18, WT1
49retinoic acid43 248.6DES, MYOD1, MYOG, ACTC1, KRT18, WT1
50tyrosine437.6WT1, KRT18, ACTC1, MYOG, MYOD1, DES

GO Terms for genes affiliated with Botryoid Rhabdomyosarcoma

About this section

Cellular components related to Botryoid Rhabdomyosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.4KRT18, DES

Biological processes related to Botryoid Rhabdomyosarcoma according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.6DES, ACTC1
2muscle cell fate commitmentGO:00426939.3MYOG, MYOD1
3skeletal muscle fiber developmentGO:00487419.3MYOG, MYOD1
4cellular response to estradiol stimulusGO:00713929.3MYOD1, MYOG
5positive regulation of muscle cell differentiationGO:00511499.2MYOG, MYOD1
6muscle cell differentiationGO:00426929.2MYOG, MYOD1
7skeletal muscle tissue developmentGO:00075199.0MYOG, MYOD1
8negative regulation of apoptotic processGO:00430668.6WT1, KRT18, ACTC1
9positive regulation of transcription from RNA polymerase II promoterGO:00459448.6WT1, MYOG, MYOD1

Molecular functions related to Botryoid Rhabdomyosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1core promoter bindingGO:00010479.1MYOG, MYOD1
2chromatin DNA bindingGO:00314909.0MYOG, MYOD1
3E-box bindingGO:00708888.8MYOG, MYOD1

Products for genes affiliated with Botryoid Rhabdomyosarcoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Botryoid Rhabdomyosarcoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet