MCID: BWN003
MIFTS: 39

Bowenoid Papulosis malady

Rare diseases category

Summaries for Bowenoid Papulosis

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Wikipedia:63 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

MalaCards based summary: Bowenoid Papulosis, also known as bp, is related to papilloma and cervical intraepithelial neoplasia. An important gene associated with Bowenoid Papulosis is FLG (filaggrin), and among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription and Regulation of Telomerase. The compounds olomoucine and indomethacine have been mentioned in the context of this disorder. Affiliated tissues include skin, cervix and tongue, and related mouse phenotypes are vision/eye and embryogenesis.

Aliases & Classifications for Bowenoid Papulosis

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Bowenoid Papulosis, Aliases & Descriptions:

Name: Bowenoid Papulosis 41 60
 
Bp 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Related Diseases for Bowenoid Papulosis

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Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 166)
idRelated DiseaseScoreTop Affiliating Genes
1papilloma30.9FLG, CDKN2A
2cervical intraepithelial neoplasia30.7TERT, CDKN2A
3lung cancer29.7PTGS2, TERT, PPARG
4colitis29.7PTGS2, PPARG
5rheumatoid arthritis29.7TERT, FLG, PTGS2
6oral cancer29.5TERT, PTGS2, CCND1, CDKN2A
7breast cancer29.1CDKN2A, CCNE1, PTGS2, PPARG, CCND1, TERT
8cervicitis10.5
9bullous pemphigoid10.5
10teratoma10.4TERT
11acquired immunodeficiency syndrome10.4
12endotheliitis10.3
13thalassemia10.3
14cystitis10.3
15systemic lupus erythematosus10.3
16leukemia10.3
17atopic dermatitis10.3
18dermatitis10.3
19eosinophilia10.3
20in situ carcinoma10.3
21lupus erythematosus10.3
22malignant peripheral nerve sheath tumor10.2TERT, CDKN2A
23chronic interstitial cystitis10.2
24tonsil squamous cell carcinoma10.2CCND1, CDKN2A
25thyroid cancer, anaplastic10.2PPARG, TERT
26laryngeal carcinoma10.2CCND1, TERT
27schizophrenia10.2
28nasopharyngeal carcinoma10.2TERT, CDKN2A
29rheumatic disease10.2FLG, PTGS2
30esophageal cancer10.2CCND1, CDKN2A
31pancreatic cancer10.1CCND1, TERT
32obesity10.1
33coronary artery disease10.1
34artery disease10.1
35pulmonary fibrosis10.1PPARG, TERT
36thyroid carcinoma, papillary10.1CCND1, PPARG
37cholangiocarcinoma10.1TERT, PTGS2
38bladder cancer, somatic10.1TERT, CDKN2A
39multiple myeloma10.1CCND1, CDKN2A
40laryngeal squamous cell carcinoma10.0CDKN2A, TERT, CCND1
41migraine10.0
42chronic granulomatous disease10.0
43dilated cardiomyopathy10.0
44neuronitis10.0
45melanoma10.0
46prostatitis10.0
47neurologic diseases10.0
48tardive dyskinesia10.0
49malignant glioma10.0TERT, CCND1, CDKN2A
50endometrial cancer10.0CDKN2A, CCND1, TERT

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to bowenoid papulosis

Symptoms for Bowenoid Papulosis

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Drugs & Therapeutics for Bowenoid Papulosis

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Drug clinical trials:

Search ClinicalTrials for Bowenoid Papulosis

Search NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

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Anatomical Context for Bowenoid Papulosis

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MalaCards organs/tissues related to Bowenoid Papulosis:

31
Skin, Cervix, Tongue

Animal Models for Bowenoid Papulosis or affiliated genes

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Publications for Bowenoid Papulosis

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Articles related to Bowenoid Papulosis:

(show top 50)    (show all 133)
idTitleAuthorsYear
1
Dermoscopic findings in bowenoid papulosis: report of two cases. (25396088)
2014
2
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. (23347880)
2013
3
Spontaneous regression of bowenoid papulosis. (24011282)
2013
4
Periungual bowenoid papulosis due to human papillomavirus type 42. (23375694)
2013
5
Bowenoid Papulosis of the Vulva and Subsequent Periungual Bowen's Disease Induced by the Same Mucosal HPVs. (22148018)
2011
6
What is your diagnosis? Bowenoid papulosis. (21284277)
2010
7
Isolated extragenital bowenoid papulosis of the toe-webs. (19326023)
2009
8
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis. (16919029)
2006
9
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. (16700665)
2006
10
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. (14731252)
2004
11
A case of Bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%. (15601490)
2004
12
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus. (12837910)
2003
13
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device. (14674917)
2003
14
Detection of human papillomavirus type 16 in bowenoid papulosis and nonbowenoid tissues. (12786880)
2003
15
Bowenoid papulosis. (12545128)
2003
16
Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome. (11606156)
2001
17
Successful topical immunotherapy of bowenoid papulosis with imiquimod. (11899127)
2001
18
The presence of HPV types 6/11, 16/18, 31/33/51 in Bowenoid papulosis demonstrated by DNA in situ hybridization. (11138919)
2000
19
Development of squamous cell carcinoma by two high-risk human papillomaviruses (HPVs), a novel HPV-67 and HPV-31 from bowenoid papulosis. (10971337)
2000
20
Facial bowenoid papulosis secondary to human papillomavirus type 16. (10233343)
1999
21
Bowenoid papulosis showing polyclonal nature. (9785012)
1998
22
Bowenoid papulosis turning to squamous cell carcinoma. (20921709)
1998
23
Bowen's disease and Bowenoid papulosis of the vulva. (7789604)
1995
24
Isolated extragenital HPV-thirties-group-positive bowenoid papulosis in an AIDS patient. (7947214)
1994
25
Bowenoid papulosis. (1848870)
1991
26
Linear bowenoid papulosis of the genitalia. A possible Koebner phenomenon. (2397968)
1990
27
Bowenoid papulosis. (2182038)
1990
28
Efficacy of interferons on bowenoid papulosis and other precancerous lesions. (1701802)
1990
29
Cervical intraepithelial neoplasia III in an adolescent with Bowenoid papulosis. (2175743)
1990
30
Human papillomavirus infection and filaggrin expression in paraffin-embedded biopsy specimens of extragenital Bowen's disease and genital bowenoid papulosis. (2164515)
1990
31
Detection of human papillomavirus type 16 DNA and papillomavirus genus-specific antigens in vulva and cervix from patients with Bowenoid papulosis. (2540130)
1989
32
Immunosuppression in men with bowenoid papulosis. (2565705)
1989
33
Bowenoid papulosis of the penis: successful management with neodymium:YAG laser. (3373609)
1988
34
Detection of human papillomavirus type 16 in bowenoid papulosis and invasive carcinoma occurring in the same patient with a history of cervical carcinoma. (2837151)
1988
35
Bowenoid papulosis. (3026758)
1987
36
Human papillomavirus type 16 in bowenoid papulosis, intraoral papillomas, and squamous cell carcinoma of the tongue. (3028282)
1987
37
Bowenoid papulosis: clinical and histological study of eight cases. (3034760)
1987
38
Bowenoid papulosis in a penile epidermal inclusion cyst. (3828216)
1987
39
Bowenoid papulosis in three-year-old girl. (3950132)
1986
40
Bowenoid papulosis of the genitalia associated with human papillomavirus DNA type 16 in an infant with atopic dermatitis. (2989808)
1985
41
HPV-16-related Bowenoid papulosis. (2861521)
1985
42
Papillomavirus common antigens. Papillomavirus antigen in verruca, benign papillomatous lesions, trichilemmoma, and bowenoid papulosis: an immunoperoxidase study. (6329106)
1984
43
Bowenoid papulosis of the chin. (6491022)
1984
44
Human papillomavirus type-16-related DNA in genital Bowen's disease and in Bowenoid papulosis. (6315601)
1983
45
Bowenoid papulosis in the perianal region. (6593959)
1983
46
Etretinate in bowenoid papulosis. (6118745)
1981
47
Bowenoid papulosis: a review. (7009074)
1981
48
Bowenoid papulosis of the penis. (7398133)
1980
49
Bowenoid papulosis of the penis. Demonstration of intranuclear viral-like particles. (7468932)
1980
50
Bowenoid papulosis. (549498)
1979

Variations for Bowenoid Papulosis

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Expression for genes affiliated with Bowenoid Papulosis

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Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for genes affiliated with Bowenoid Papulosis

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Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 35)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5CCND1, TERT
29.5TERT, CCND1
3
Show member pathways
9.5CCND1, CDKN2A
49.4PPARG, CCND1
5
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.3PTGS2, PPARG
69.3PTGS2, PPARG
79.3PTGS2, CCND1
89.2TERT, CCNE1
99.1CCNE1, PPARG
109.1CCNE1, CCND1
119.1CCNE1, CCND1
12
Show member pathways
Development Ligand dependent activation of the ESR1 AP 1 pathway58
9.1CCNE1, CCND1
13
Show member pathways
Cell cycle ESR1 regulation of G1 S transition58
Immune response MIF JAB1 signaling58
Cell cycle Cell cycle generic schema 58
9.1CCND1, CCNE1
149.1CCND1, CCNE1
159.1CCND1, CCNE1
169.1CCND1, CCNE1
17
Show member pathways
9.1CCND1, CCNE1
18
Show member pathways
9.1TERT, CDKN2A, PPARG
199.1TERT, CCND1, CDKN2A
208.7CDKN2A, CCNE1, CCND1
21
Show member pathways
DNA damage response36
8.7CCND1, CDKN2A, CCNE1
22
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation58
8.7CDKN2A, CCNE1, CCND1
23
Show member pathways
Cell cycle36
8.7CDKN2A, CCNE1, CCND1
24
Show member pathways
8.7CDKN2A, CCNE1, CCND1
25
Show member pathways
8.7CDKN2A, CCND1, CCNE1
26
Show member pathways
Signaling Pathways in Glioblastoma36
8.7CCNE1, CCND1, CDKN2A
278.7CCNE1, CCND1, CDKN2A
28
Show member pathways
8.7CCNE1, CDKN2A, CCND1
298.5PTGS2, CCNE1, CCND1
308.5PTGS2, CCNE1, CCND1
31
Show member pathways
8.3CCND1, CCNE1, TERT, CDKN2A
32
Show member pathways
8.1CDKN2A, CCND1, CCNE1, PTGS2
338.1PTGS2, CCNE1, CCND1, CDKN2A
34
Show member pathways
8.1CCNE1, CCND1, PTGS2, CDKN2A
357.5CDKN2A, CCNE1, PTGS2, CCND1, PPARG

Compounds for genes affiliated with Bowenoid Papulosis

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Compounds related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 78)
idCompoundScoreTop Affiliating Genes
1olomoucine43 1210.8CDKN2A, CCND1
2indomethacine439.8PPARG, PTGS2
3bexarotene43 28 1211.8CCND1, PPARG
4r-flurbiprofen439.7CCND1, PTGS2
5balsalazide43 1210.7PTGS2, PPARG
6cyclopentenone439.7PTGS2, PPARG
7nimesulide43 1210.7PTGS2, PPARG
8p00001439.7CDKN2A, CCND1
9nickel43 2410.6CDKN2A, FLG
10gw966243 2810.6PPARG, PTGS2
11etodolac43 1210.6CCND1, PTGS2
12thiazolidinedione439.6CCND1, PPARG
13crcs439.6CDKN2A, CCND1
14depsipeptide439.5CDKN2A, CCND1, TERT
15thymidylate439.5CCND1, TERT, CDKN2A
16adriamycin439.5CDKN2A, CCND1, TERT
17nicotine43 28 49 1212.5CCND1, FLG, CDKN2A
18arsenite43 2410.4TERT, CCND1, CDKN2A
19retinoid439.3FLG, PPARG, CCND1
20ns 39843 5910.3CCND1, PTGS2
21butyrate439.3CCND1, CDKN2A, TERT
22paclitaxel43 49 1211.3TERT, CDKN2A, CCND1
23exisulind439.3PTGS2, CCND1, PPARG
24rofecoxib43 49 28 1212.2PPARG, CCND1, PTGS2
25sulindac sulfide439.2CCND1, PPARG, PTGS2
26ciglitazone43 2810.2CCND1, PTGS2, PPARG
27sulindac43 1210.2CCND1, PTGS2, PPARG
28rapamycin439.2PPARG, TERT, CCND1
2915-deoxy-delta-12,14-prostaglandin j2439.2CCND1, PTGS2, PPARG
30celecoxib43 59 28 49 24 1214.2CCND1, PTGS2, PPARG
31resveratrol43 59 24 1212.2CCND1, PTGS2, PPARG
32troglitazone43 28 59 1212.2CCND1, PTGS2, PPARG
33curcumin439.2CCND1, PTGS2, PPARG
34sb 20358043 5910.1PPARG, CCND1, PTGS2
35pd 98,059439.0TERT, CCND1, PTGS2
36sulfasalazine28 43 49 1212.0PPARG, PTGS2
37doxorubicin43 49 1211.0CDKN2A, CCND1, TERT
38testosterone43 59 24 1211.9CDKN2A, CCND1, TERT, PPARG
39nitric oxide43 24 1210.9TERT, PTGS2, FLG, CDKN2A
40egcg438.9TERT, CDKN2A, CCND1, PTGS2
41gf 109203x43 599.9FLG, PTGS2, PPARG, CCND1
42cisplatin43 49 59 1211.9CCND1, TERT, PTGS2, CDKN2A
43ly294002438.8CCND1, PTGS2, TERT, PPARG
44cycloheximide438.7CCND1, CDKN2A, PPARG, PTGS2
45retinoic acid43 249.6CCND1, PPARG, FLG, TERT, CDKN2A
46n acetylcysteine438.4PPARG, TERT, PTGS2, CCND1, CDKN2A
47genistein43 28 59 2 24 1213.4CDKN2A, CCND1, PTGS2, TERT, PPARG
48vegf438.4CDKN2A, PTGS2, TERT, PPARG, CCND1
49serine438.3CCND1, CCNE1, FLG, TERT, CDKN2A
50estrogen437.6PPARG, TERT, PTGS2, CCNE1, CCND1, CDKN2A

GO Terms for genes affiliated with Bowenoid Papulosis

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Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein kinase holoenzyme complexGO:00003078.8CCNE1, CCND1
2nucleolusGO:00057308.3CDKN2A, CCND1, CCNE1, TERT
3nucleoplasmGO:00056547.6CDKN2A, CCND1, CCNE1, TERT, PPARG

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1replicative senescenceGO:00903999.9CDKN2A, TERT
2organ regenerationGO:00311009.6CCND1, PPARG
3brown fat cell differentiationGO:00508739.5PPARG, PTGS2
4response to estrogenGO:00436279.5CCND1, PPARG
5regulation of blood pressureGO:00082179.3PTGS2, PPARG
6activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.2CDKN2A, PPARG
7cell divisionGO:00513019.1CCND1, CCNE1
8response to drugGO:00424939.0CCND1, PTGS2, PPARG
9G1/S transition of mitotic cell cycleGO:00000828.9CDKN2A, CCND1, CCNE1
10mitotic cell cycleGO:00002788.8CCNE1, CCND1, CDKN2A
11positive regulation of transcription, DNA-templatedGO:00458938.6PPARG, CCNE1, CDKN2A

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase regulator activityGO:00165389.0CCND1, CCNE1
2protein kinase bindingGO:00199018.7CDKN2A, CCND1, CCNE1
3enzyme bindingGO:00198998.5CCND1, PTGS2, PPARG

Products for genes affiliated with Bowenoid Papulosis

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Sources for Bowenoid Papulosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet