BP
MCID: BWN003
MIFTS: 34

Bowenoid Papulosis (BP) malady

Category: Rare diseases

Aliases & Classifications for Bowenoid Papulosis

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Aliases & Descriptions for Bowenoid Papulosis:

Name: Bowenoid Papulosis 48 68
 
Bp 48

Classifications:



Summaries for Bowenoid Papulosis

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Wikipedia:71 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

MalaCards based summary: Bowenoid Papulosis, also known as BP, is related to interstitial cystitis and d-bifunctional protein deficiency. An important gene associated with Bowenoid Papulosis is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways are miRNAs involved in DNA damage response and Cell cycle Cell cycle (generic schema). Affiliated tissues include tongue, cervix and skin, and related mouse phenotypes are digestive/alimentary and integument.

Related Diseases for Bowenoid Papulosis

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Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 80)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial cystitis11.4
2d-bifunctional protein deficiency10.8
3popliteal pterygium syndrome 2, lethal type10.8
4bart-pumphrey syndrome10.8
5vertebrobasilar insufficiency10.8
6bipolar i disorder10.8
7popliteal pterygium syndrome, bartsocas-papas type10.8
8bowen's disease10.4
9squamous cell carcinoma10.4
1013q12.3 microdeletion syndrome10.2CCND1, CDKN2A
11skeletal tuberculosis10.2CCND1, CDKN2A
12anal neuroendocrine tumor10.2CCND1, CDKN2A
13episodic ataxia10.2CCND1, CDKN2A
14oro-mandibular-limb hypogenesis syndrome10.2CCND1, CDKN2A
15brain stem medulloblastoma10.2CCND1, CDKN2A
16cervical verrucous carcinoma10.2CCND1, CDKN2A
17striated muscle rhabdoid tumor10.2CCND1, CDKN2A
18cervicitis10.2
19tricuspid valve prolapse10.1CDKN2A, PTGS2
20acquired hemangioma10.1CDKN2A, PTGS2
21estrogen-receptor positive breast cancer10.1CCND1, CDKN2A
22urethral verrucous carcinoma10.1CDKN2A, PTGS2
23pseudo-meigs syndrome10.1CDKN2A, FLG
24acute disseminated encephalomyelitis10.1CDKN2A, TERT
25tamoxifen-related endometrial lesion10.1CDKN2A, PTGS2
26statin toxicity10.1CCND1, PTGS2
27caroli disease10.1CCND1, CDKN2A
28ideomotor apraxia10.1CCND1, PTGS2
29connective tissue benign neoplasm10.1CCND1, CDKN2A
30bullous pemphigoid10.0
31pelvic varices10.0CCNE1, TERT
32charcot-marie-tooth disease type 2n10.0CDKN2A, TERT
33mucositis10.0
34papilloma10.0
35acquired immunodeficiency syndrome10.0
36active vestibular meniere's disease10.0CCND1, CDKN2A, PTGS2
37advanced sleep phase syndrome10.0CCND1, CDKN2A, PTGS2
38progesterone-receptor positive breast cancer10.0CCND1, CDKN2A, PTGS2
39ornithinemia10.0CCND1, CDKN2A, PTGS2
40spinal muscular atrophy with progressive myoclonic epilepsy10.0CCND1, CDKN2A, PTGS2
41vestibular gland benign neoplasm10.0CCND1, CDKN2A, PTGS2
42nodular cutaneous amyloidosis10.0CDKN2A, TERT
43facial dermatosis10.0CCND1, CDKN2A, PTGS2
44mitochondrial encephalomyopathy10.0CDKN2A, PTGS2
45in situ pulmonary adenocarcinoma10.0CCND1, CDKN2A, PTGS2
46malignant pleural solitary fibrous tumor10.0CCND1, CDKN2A, PTGS2
47ovarian mucinous neoplasm10.0PTGS2, TERT
48proctitis10.0CCND1, CDKN2A, PTGS2
49autonomic nervous system neoplasm10.0CCND1, CDKN2A, FLG
50hypogonadotropic hypogonadism 20 with or without anosmia10.0CCND1, CDKN2A, PTGS2

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to bowenoid papulosis

Symptoms & Phenotypes for Bowenoid Papulosis

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MGI Mouse Phenotypes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

41 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.0CCND1, CCNE1, CDKN2A, PTGS2, TERT
2MP:00107718.7CCND1, CCNE1, CDKN2A, PPARG, PTGS2
3MP:00028738.4CCND1, CCNE1, PPARG, PTGS2, TERT
4MP:00053848.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
5MP:00053798.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
6MP:00053788.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
7MP:00053978.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
8MP:00053878.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
9MP:00020068.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
10MP:00036318.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
11MP:00053898.0CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
12MP:00053907.3CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT

Drugs & Therapeutics for Bowenoid Papulosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

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Anatomical Context for Bowenoid Papulosis

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MalaCards organs/tissues related to Bowenoid Papulosis:

36
Tongue, Cervix, Skin

Publications for Bowenoid Papulosis

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Articles related to Bowenoid Papulosis:

(show top 50)    (show all 140)
idTitleAuthorsYear
1
Bowenoid papulosis in a linear distribution. (27279825)
2016
2
Aminolevulinic acid photodynamic therapy for bowenoid papulosis. (25751357)
2015
3
Bowenoid papulosis. (26692627)
2015
4
High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review. (26693089)
2015
5
Dermoscopic findings in bowenoid papulosis: report of two cases. (25396088)
2014
6
Dramatic clearance of HIV-associated bowenoid papulosis using combined oral acitretin and topical 5% imiquimod. (25116965)
2014
7
Bowenoid papulosis successfully treated with imiquimod 5% cream. (24909216)
2014
8
A case of isolated bowenoid papulosis of the nipple. (24966640)
2014
9
Spontaneous regression of bowenoid papulosis. (24011282)
2013
10
Bowenoid papulosis and invasive Bowen's disease: a multidisciplinary approach. (22717936)
2013
11
Expression of activation-induced cytidine deaminase in Bowenoid papulosis. (24126385)
2013
12
Whither bowenoid papulosis? (23336842)
2013
13
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. (23347880)
2013
14
Expression of p16 protein in lesional and perilesional condyloma acuminata and bowenoid papulosis: clinical significance and diagnostic implications. (23706650)
2013
15
Expression of cyclin D1 and cyclin E significantly associates with human papillomavirus subtypes in Bowenoid papulosis. (23044415)
2013
16
Periungual bowenoid papulosis due to human papillomavirus type 42. (23375694)
2013
17
Multiple linear bowenoid papulosis without surrounding papules. (22221073)
2012
18
A combined assay of hTERT and E6 oncoprotein to identify virus-infected keratinocytes with higher telomerase activity in human papillomaviruses 16 and 18-related bowenoid papulosis. (22688392)
2012
19
Successful treatment with fluoropyrimidine TS-1 of human papillomavirus type 16-detected multiple oral bowenoid papulosis in an elderly woman. (22266463)
2012
20
Coexistence of Bowenoid papulosis and Bowen's disease in a patient with systemic lupus erythematosus. (22142328)
2012
21
Bowenoid Papulosis of the Vulva and Subsequent Periungual Bowen's Disease Induced by the Same Mucosal HPVs. (22148018)
2011
22
Detection of human papillomavirus type 67 from bowenoid papulosis. (20974556)
2010
23
What is your diagnosis? Bowenoid papulosis. (21284277)
2010
24
Bowenoid papulosis of the genitalia successfully treated with topical tazarotene: a report of two cases. (20161865)
2009
25
The expressions of PPAR-gamma, COX-2 in the lesions of patients with condyloma acuminatum and bowenoid papulosis]. (19627000)
2009
26
Topical treatment of bowenoid papulosis of the penis with imiquimod. (19207667)
2009
27
Isolated extragenital bowenoid papulosis of the toe-webs. (19326023)
2009
28
Spontaneous regression of bowenoid papulosis in a patient with acquired immunodeficiency syndrome after an increase in peripheral CD4+ T lymphocytes. (19200210)
2009
29
Differences in imiquimod treatment outcome in two patients with bowenoid papulosis containing either episomal or integrated human papillomavirus 16. (17008876)
2007
30
Angiolymphoid hyperplasia with eosinophilia mimicking Bowenoid papulosis. (17263828)
2007
31
Increased human papillomavirus type 31 DNA load in a verrucous high-grade intraepithelial neoplasia of a human immunodeficiency virus-infected patient with extensive bowenoid papulosis. (17300265)
2007
32
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. (16700665)
2006
33
P16(INK4A) expression in Bowen's disease and Bowenoid papulosis. (17100385)
2006
34
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis. (16919029)
2006
35
Oral bowenoid papulosis in an HIV-positive male. (16504866)
2006
36
Oral bowenoid papulosis in an HIV-positive male. (16997106)
2006
37
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. (14731252)
2004
38
A case of Bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%. (15601490)
2004
39
Elevated amount of human papillomavirus 31 DNA in a squamous cell carcinoma developed from bowenoid papulosis. (15539898)
2004
40
Bowenoid papulosis at the site of prior herpes progenitalis. (15538089)
2004
41
Bowenoid papulosis in a patient with AIDS treated with imiquimod: case report. (15588562)
2004
42
Human papillomavirus-32-positive extragenital Bowenoid papulosis (BP) in a HIV patient with typical genital BP localization. (15389001)
2004
43
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device. (14674917)
2003
44
Bowenoid papulosis. (12545128)
2003
45
A cardiac allograft recipient with Bowen's disease on a finger and concurrent perianal bowenoid papulosis. (12773804)
2003
46
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus. (12837910)
2003
47
Bowenoid papulosis successfully treated with imiquimod. (12702095)
2003
48
Bowenoid papulosis of the vulva-immunotherapeutical approach with topical imiquimod. (14504882)
2003
49
Detection of human papillomavirus type 16 in bowenoid papulosis and nonbowenoid tissues. (12786880)
2003
50
Topical imiquimod for Bowenoid papulosis in an HIV-positive woman. (12353717)
2002

Variations for Bowenoid Papulosis

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Expression for genes affiliated with Bowenoid Papulosis

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Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for genes affiliated with Bowenoid Papulosis

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Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 28)
idSuper pathwaysScoreTop Affiliating Genes
19.6CCND1, CCNE1
2
Show member pathways
9.6CCND1, CCNE1
3
Show member pathways
9.6CCND1, CCNE1
49.6CCND1, CCNE1
59.6CCND1, CCNE1
6
Show member pathways
9.5CCND1, PTGS2
79.5CCND1, PTGS2
89.4CCND1, TERT
99.2CCND1, PPARG
109.2CCND1, PPARG
119.2CCND1, CCNE1, CDKN2A
12
Show member pathways
9.2CCND1, CCNE1, CDKN2A
139.2CCND1, CCNE1, CDKN2A
14
Show member pathways
9.2CCND1, CCNE1, CDKN2A
159.2CCND1, CCNE1, CDKN2A
169.2CCND1, CCNE1, CDKN2A
17
Show member pathways
9.2CCND1, CCNE1, CDKN2A
18
Show member pathways
9.2CCND1, CCNE1, CDKN2A
19
Show member pathways
9.2CCND1, CCNE1, CDKN2A
20
Show member pathways
9.2CCND1, CCNE1, CDKN2A
219.2CCNE1, PPARG
229.1PPARG, PTGS2
239.1CCND1, CCNE1, PTGS2
249.1CCND1, CCNE1, PTGS2
259.1CCND1, CDKN2A, TERT
26
Show member pathways
8.7CCND1, PPARG, PTGS2
278.7CCND1, CCNE1, CDKN2A, PTGS2
287.9CCND1, CCNE1, CDKN2A, PPARG, PTGS2

GO Terms for genes affiliated with Bowenoid Papulosis

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Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein kinase holoenzyme complexGO:000030710.4CCND1, CCNE1
2nucleusGO:00056346.7CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1regulation of protein kinase activityGO:004585910.3CCND1, CCNE1
2regulation of protein stabilityGO:003164710.2CDKN2A, TERT
3replicative senescenceGO:009039910.2CDKN2A, TERT
4response to organonitrogen compoundGO:001024310.0CCND1, PTGS2
5animal organ regenerationGO:003110010.0CCND1, PPARG
6G1/S transition of mitotic cell cycleGO:000008210.0CCND1, CCNE1, CDKN2A
7response to estrogenGO:00436279.9CCND1, PPARG
8regulation of blood pressureGO:00082179.8PPARG, PTGS2
9negative regulation of cell proliferationGO:00082859.5CDKN2A, PPARG, PTGS2
10positive regulation of apoptotic processGO:00430659.4CDKN2A, PPARG, PTGS2
11telomere maintenanceGO:00007239.4CCNE1, TERT
12response to drugGO:00424939.4CCND1, PPARG, PTGS2
13response to organic cyclic compoundGO:00140709.3CCND1, PPARG, PTGS2
14response to organic substanceGO:00100339.2CCND1, PPARG, PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase regulator activityGO:001653810.3CCND1, CCNE1
2protein kinase bindingGO:00199019.9CCND1, CCNE1, CDKN2A
3enzyme bindingGO:00198999.4CCND1, PPARG, PTGS2
4transcription factor bindingGO:00081348.9CCND1, CDKN2A, PPARG

Sources for Bowenoid Papulosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet