MCID: BWN003
MIFTS: 34

Bowenoid Papulosis malady

Category: Rare diseases

Aliases & Classifications for Bowenoid Papulosis

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Aliases & Descriptions for Bowenoid Papulosis:

Name: Bowenoid Papulosis 47 67
 
Bp 47

Classifications:



Summaries for Bowenoid Papulosis

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Wikipedia:70 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

MalaCards based summary: Bowenoid Papulosis, also known as bp, is related to interstitial cystitis and d-bifunctional protein deficiency, and has symptoms including leser-trélat sign An important gene associated with Bowenoid Papulosis is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways are Bladder cancer and DNA damage_ATM/ATR regulation of G1/S checkpoint. Affiliated tissues include tongue, cervix and skin, and related mouse phenotypes are digestive/alimentary and cardiovascular system.

Related Diseases for Bowenoid Papulosis

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Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial cystitis11.3
2d-bifunctional protein deficiency10.8
3popliteal pterygium syndrome 2, lethal type10.8
4bart-pumphrey syndrome10.8
5vertebrobasilar insufficiency10.8
6bipolar i disorder10.8
7popliteal pterygium syndrome, bartsocas-papas type10.8
8bowen's disease10.4
9skeletal tuberculosis10.4CCND1, CDKN2A
10gallbladder squamous cell carcinoma10.4CCND1, CDKN2A
11bladder verrucous squamous cell carcinoma10.4CCND1, CDKN2A
12oligodendroglioma10.4CCND1, CDKN2A
13leukoencephalopathy palmoplantar keratoderma10.4CCND1, CDKN2A
14ductal carcinoma in situ10.4CCND1, CDKN2A
15mild phosphoribosylpyrophosphate synthetase superactivity10.4CCND1, CDKN2A
16histidine metabolism disease10.4CCND1, CDKN2A
17integumentary system cancer10.4CCND1, CDKN2A
18bilateral retinoblastoma10.3CCND1, CDKN2A
19pharynx cancer10.3CCND1, CDKN2A
20malignant giant cell tumor of soft parts10.3CDKN2A, PTGS2
21ascending colon cancer10.3CCND1, CDKN2A
22esophagus verrucous carcinoma10.3CDKN2A, PTGS2
23pituitary carcinoma10.3CDKN2A, PTGS2
24hodgkin's granuloma10.3CCND1, CDKN2A
25stroma-dominant and stroma-poor composite ganglioneuroblastoma10.3CDKN2A, PTGS2
26epididymis cancer10.3CCND1, PTGS2
27richter's syndrome10.3CCND1, CDKN2A
28renal hypodysplasia10.3CDKN2A, FLG
29fallopian tube mucinous adenocarcinoma10.2CDKN2A, PTGS2
30periapical granuloma10.2CCND1, PTGS2
31hypersplenism10.2CDKN2A, TERT
32heavy chain disease10.2CDKN2A, PTGS2
33stenosis of lacrimal sac10.2CCND1, CDKN2A
34x-linked congenital generalized hypertrichosis10.2CDKN2A, TERT
35central centrifugal cicatricial alopecia10.2CDKN2A, TERT
36oral lichen planus10.2CCND1, PTGS2
37learning disability10.2CDKN2A, PTGS2
38trachea sarcoma10.2CCND1, CDKN2A
39cervicitis10.2
40stromal keratitis10.2CDKN2A, TERT
41chondroma10.2CCND1, CDKN2A
42penis carcinoma in situ10.2CDKN2A, PTGS2
43arrhythmogenic right ventricular cardiomyopathy10.1CCND1, PTGS2
44renal tuberculosis10.1CCNE1, TERT
45peritoneal serous adenocarcinoma10.1CCND1, PTGS2
46gastric cancer10.1CCND1, CDKN2A
47bullous pemphigoid10.0
48papilloma10.0
49adult mesoblastic nephroma10.0CDKN2A, PTGS2
50grade iii astrocytoma10.0CDKN2A, PPARG

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to bowenoid papulosis

Symptoms for Bowenoid Papulosis

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UMLS symptoms related to Bowenoid Papulosis:


leser-trélat sign

Drugs & Therapeutics for Bowenoid Papulosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

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Anatomical Context for Bowenoid Papulosis

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MalaCards organs/tissues related to Bowenoid Papulosis:

35
Tongue, Cervix, Skin

Animal Models for Bowenoid Papulosis or affiliated genes

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MGI Mouse Phenotypes related to Bowenoid Papulosis:

40 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.0CCND1, CCNE1, CDKN2A, PTGS2, TERT
2MP:00053858.8CCND1, CCNE1, CDKN2A, PPARG, PTGS2
3MP:00107718.7CCND1, CCNE1, CDKN2A, PPARG, PTGS2
4MP:00028738.4CCND1, CCNE1, PPARG, PTGS2, TERT
5MP:00053848.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
6MP:00053798.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
7MP:00053788.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
8MP:00053978.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
9MP:00053878.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
10MP:00020068.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
11MP:00036318.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
12MP:00053898.0CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
13MP:00053907.3CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT

Publications for Bowenoid Papulosis

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Articles related to Bowenoid Papulosis:

(show top 50)    (show all 140)
idTitleAuthorsYear
1
Bowenoid papulosis in a linear distribution. (27279825)
2016
2
High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review. (26693089)
2015
3
Dramatic clearance of HIV-associated bowenoid papulosis using combined oral acitretin and topical 5% imiquimod. (25116965)
2014
4
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. (23347880)
2013
5
Periungual bowenoid papulosis due to human papillomavirus type 42. (23375694)
2013
6
Expression of activation-induced cytidine deaminase in Bowenoid papulosis. (24126385)
2013
7
Expression of cyclin D1 and cyclin E significantly associates with human papillomavirus subtypes in Bowenoid papulosis. (23044415)
2013
8
Whither bowenoid papulosis? (23336842)
2013
9
What is your diagnosis? Bowenoid papulosis. (21284277)
2010
10
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. (16700665)
2006
11
P16(INK4A) expression in Bowen's disease and Bowenoid papulosis. (17100385)
2006
12
Oral bowenoid papulosis in an HIV-positive male. (16504866)
2006
13
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. (14731252)
2004
14
A case of Bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%. (15601490)
2004
15
Bowenoid papulosis. (12545128)
2003
16
Extragenital bowenoid papulosis associated with atypical human papillomavirus genotypes. (11992183)
2002
17
Isolated human papillomavirus 18-positive extragenital bowenoid papulosis and idiopathic CD4+ lymphocytopenia. (11260028)
2001
18
Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome. (11606156)
2001
19
Topical cidofovir for bowenoid papulosis in an HIV-infected patient. (11260042)
2001
20
The presence of HPV types 6/11, 16/18, 31/33/51 in Bowenoid papulosis demonstrated by DNA in situ hybridization. (11138919)
2000
21
Facial bowenoid papulosis secondary to human papillomavirus type 16. (10233343)
1999
22
HPV 18-induced pigmented bowenoid papulosis of the neck. (10188688)
1999
23
Bowenoid papulosis transforming into squamous cell carcinoma of the genitalia. (10583075)
1999
24
Bowenoid papulosis showing polyclonal nature. (9785012)
1998
25
Bowenoid papulosis turning to squamous cell carcinoma. (20921709)
1998
26
Bowenoid papulosis of the penis. (9313685)
1997
27
Bowenoid papulosis in males in Australia. (1316990)
1992
28
The presence of HPV types 6/11, 13, 16 and 33 in bowenoid papulosis in an HIV-positive male, demonstrated by DNA in situ hybridization. (1648931)
1991
29
Extra-anogenital HPV16-related bowenoid papulosis. (1655620)
1991
30
Linear bowenoid papulosis of the genitalia. A possible Koebner phenomenon. (2397968)
1990
31
Efficacy of interferons on bowenoid papulosis and other precancerous lesions. (1701802)
1990
32
Cervical intraepithelial neoplasia III in an adolescent with Bowenoid papulosis. (2175743)
1990
33
Detection of human papillomavirus type 16 DNA and papillomavirus genus-specific antigens in vulva and cervix from patients with Bowenoid papulosis. (2540130)
1989
34
Immunosuppression in men with bowenoid papulosis. (2565705)
1989
35
Human papillomavirus-35-positive bowenoid papulosis of the anogenital area and concurrent human papillomavirus-35-positive verruca with bowenoid dysplasia of the periungual area. (2540719)
1989
36
Human papillomavirus type 16 in bowenoid papulosis, intraoral papillomas, and squamous cell carcinoma of the tongue. (3028282)
1987
37
Bowenoid papulosis: clinical and histological study of eight cases. (3034760)
1987
38
Bowenoid papulosis of the vulva--a report of three cases with a review of the literature. (3331968)
1987
39
Bowenoid papulosis of the male and female genitalia: risk of cervical neoplasia. (3007587)
1986
40
Bowenoid papulosis. A clinicopathologic study with ultrastructural observations. (3002589)
1986
41
Successful treatment of condylomata acuminata and bowenoid papulosis with subcutaneous injections of low-dose recombinant interferon-alpha. (3729505)
1986
42
Bowenoid papulosis of the genitalia associated with human papillomavirus DNA type 16 in an infant with atopic dermatitis. (2989808)
1985
43
Bowenoid papulosis. Presence of human papillomavirus (HPV) structural antigens and of HPV 16-related DNA sequences. (2990353)
1985
44
Bowenoid papulosis of the chin. (6491022)
1984
45
Human papillomavirus type-16-related DNA in genital Bowen's disease and in Bowenoid papulosis. (6315601)
1983
46
Immunoperoxidase localization of papillomavirus antigen in cutaneous warts and bowenoid papulosis. (6313865)
1983
47
Etretinate in bowenoid papulosis. (6118745)
1981
48
Viral-like particles in Bowenoid papulosis. (7325343)
1981
49
Bowenoid papulosis of the penis. (7398133)
1980
50
Bowenoid papulosis. (549498)
1979

Variations for Bowenoid Papulosis

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Expression for genes affiliated with Bowenoid Papulosis

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Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for genes affiliated with Bowenoid Papulosis

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Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 27)
idSuper pathwaysScoreTop Affiliating Genes
19.7CCND1, CDKN2A
29.6CCND1, CCNE1
39.6CCND1, CCNE1
4
Show member pathways
9.6CCND1, CCNE1
5
Show member pathways
9.6CCND1, CCNE1
69.6CCND1, CCNE1
79.4CCND1, TERT
89.4CCNE1, TERT
99.2CCND1, PPARG
10
Show member pathways
9.2CCND1, CCNE1, CDKN2A
11
Show member pathways
9.2CCND1, CCNE1, CDKN2A
12
Show member pathways
9.2CCND1, CCNE1, CDKN2A
139.2CCND1, CCNE1, CDKN2A
14
Show member pathways
9.2CCND1, CCNE1, CDKN2A
15
Show member pathways
9.2CCND1, CCNE1, CDKN2A
169.2CCND1, CCNE1, CDKN2A
179.2CCND1, CCNE1, CDKN2A
18
Show member pathways
9.2CCND1, CCNE1, CDKN2A
199.2CCNE1, PPARG
209.1PPARG, PTGS2
219.1CCND1, CCNE1, PTGS2
229.1CCND1, CCNE1, PTGS2
239.1CCND1, CCNE1, PTGS2
249.1CCND1, CDKN2A, TERT
25
Show member pathways
8.7CCND1, PPARG, PTGS2
268.7CCND1, CCNE1, CDKN2A, PTGS2
277.9CCND1, CCNE1, CDKN2A, PPARG, PTGS2

GO Terms for genes affiliated with Bowenoid Papulosis

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Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein kinase holoenzyme complexGO:000030710.2CCND1, CCNE1
2nucleusGO:00056346.7CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1response to vitamin EGO:003319710.2CCND1, CCNE1
2response to corticosteroneGO:005141210.1CCND1, CCNE1
3response to organonitrogen compoundGO:001024310.0CCND1, PTGS2
4replicative senescenceGO:009039910.0CDKN2A, TERT
5response to cytokineGO:00340979.9CCNE1, PTGS2
6G1/S transition of mitotic cell cycleGO:00000829.5CCND1, CCNE1, CDKN2A
7regulation of blood pressureGO:00082179.5PPARG, PTGS2
8animal organ regenerationGO:00311009.2CCND1, CCNE1, PPARG
9response to estradiolGO:00323559.2CCND1, CCNE1, PTGS2
10response to organic cyclic compoundGO:00140709.1CCND1, PPARG, PTGS2
11response to organic substanceGO:00100339.1CCND1, PPARG, PTGS2
12negative regulation of cell proliferationGO:00082858.7CDKN2A, PPARG, PTGS2
13response to drugGO:00424938.3CCND1, CCNE1, PPARG, PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase regulator activityGO:001653810.1CCND1, CCNE1
2protein kinase bindingGO:00199018.9CCND1, CCNE1, CDKN2A
3enzyme bindingGO:00198998.7CCND1, PPARG, PTGS2

Sources for Bowenoid Papulosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet