MCID: BWN003
MIFTS: 34

Bowenoid Papulosis malady

Rare diseases category

Aliases & Classifications for Bowenoid Papulosis

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Aliases & Descriptions for Bowenoid Papulosis:

Name: Bowenoid Papulosis 45 65
 
Bp 45


Classifications:



Summaries for Bowenoid Papulosis

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Wikipedia:68 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

MalaCards based summary: Bowenoid Papulosis, also known as bp, is related to gastrointestinal system cancer and nervous system disease. An important gene associated with Bowenoid Papulosis is FLG (Filaggrin), and among its related pathways are DNA damage_ATM/ATR regulation of G1/S checkpoint and GADD45 Pathway. Affiliated tissues include tongue, cervix and skin, and related mouse phenotypes are digestive/alimentary and normal.

Related Diseases for Bowenoid Papulosis

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Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 387)
idRelated DiseaseScoreTop Affiliating Genes
1gastrointestinal system cancer30.0CCND1, PTGS2
2nervous system disease29.7CCND1, CDKN2A, TERT
3hepatocellular carcinoma29.1CCND1, CDKN2A, PTGS2, TERT
4lung cancer28.7CCND1, CDKN2A, PPARG, PTGS2, TERT
5cervicitis10.6
6hypertension, essential10.6
7bullous pemphigoid10.5
8acquired immunodeficiency syndrome10.4
9papilloma10.4
10pulmonary hypertension10.3
11cystitis10.3
12hypertension, diastolic10.3
13systemic lupus erythematosus10.3
14leukemia10.3
15atopic dermatitis10.3
16dermatitis10.3
17eosinophilia10.3
18in situ carcinoma10.3
19lupus erythematosus10.3
20cervical intraepithelial neoplasia10.3
21idiopathic cd4 lymphocytopenia10.3
22pulmonary hypertension, primary, 210.3
23thalassemia10.3
24endotheliitis10.3
25breast cancer10.2
26hypertensive heart disease10.2
27obesity10.2
28congenital heart disease10.2
29urinary system disease10.2
30breast sarcoma10.1CCND1, CDKN2A
31oxyphilic endometrial endometrioid adenocarcinoma10.1CCND1, CDKN2A
32schizophrenia10.1
33myocardial infarction10.1
34stroke, ischemic10.1
35coronary heart disease 510.1
36aplastic anemia10.1
37autoimmune disease 410.1
38autoimmune disease 210.1
39leukemia, chronic myeloid, somatic10.1
40child syndrome10.1
41chronic kidney failure10.1
42chronic leukemia10.1
43primary hyperoxaluria10.1
44chronic interstitial cystitis10.1
45chronic monocytic leukemia10.1
46bone marrow cancer10.1
47chronic myeloproliferative disease10.1
48hypersensitivity reaction type ii disease10.1
49kidney disease10.1
50myeloid leukemia10.1

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to bowenoid papulosis

Symptoms for Bowenoid Papulosis

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Drugs & Therapeutics for Bowenoid Papulosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

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Anatomical Context for Bowenoid Papulosis

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MalaCards organs/tissues related to Bowenoid Papulosis:

33
Tongue, Cervix, Skin

Animal Models for Bowenoid Papulosis or affiliated genes

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MGI Mouse Phenotypes related to Bowenoid Papulosis:

38 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.1CCND1, CCNE1, CDKN2A, PTGS2, TERT
2MP:00028738.0CCND1, CCNE1, PPARG, PTGS2, TERT
3MP:00053907.5CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
4MP:00107717.5CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2
5MP:00020067.3CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
6MP:00053767.3CCND1, CDKN2A, FLG, PPARG, PTGS2, TERT
7MP:00036317.2CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
8MP:00053797.1CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
9MP:00053847.1CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2
10MP:00107687.0CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2
11MP:00053787.0CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2
12MP:00053896.8CCND1, CCNE1, CDKN2A, PPARG, PTGS2, TERT
13MP:00053876.7CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2
14MP:00053976.6CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2

Publications for Bowenoid Papulosis

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Articles related to Bowenoid Papulosis:

(show top 50)    (show all 134)
idTitleAuthorsYear
1
Dermoscopic findings in bowenoid papulosis: report of two cases. (25396088)
2014
2
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. (23347880)
2013
3
Spontaneous regression of bowenoid papulosis. (24011282)
2013
4
Periungual bowenoid papulosis due to human papillomavirus type 42. (23375694)
2013
5
Bowenoid Papulosis of the Vulva and Subsequent Periungual Bowen's Disease Induced by the Same Mucosal HPVs. (22148018)
2011
6
What is your diagnosis? Bowenoid papulosis. (21284277)
2010
7
Isolated extragenital bowenoid papulosis of the toe-webs. (19326023)
2009
8
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis. (16919029)
2006
9
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. (16700665)
2006
10
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. (14731252)
2004
11
A case of Bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%. (15601490)
2004
12
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus. (12837910)
2003
13
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device. (14674917)
2003
14
Detection of human papillomavirus type 16 in bowenoid papulosis and nonbowenoid tissues. (12786880)
2003
15
Bowenoid papulosis. (12545128)
2003
16
Isolated human papillomavirus 18-positive extragenital bowenoid papulosis and idiopathic CD4+ lymphocytopenia. (11260028)
2001
17
Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome. (11606156)
2001
18
The presence of HPV types 6/11, 16/18, 31/33/51 in Bowenoid papulosis demonstrated by DNA in situ hybridization. (11138919)
2000
19
Development of squamous cell carcinoma by two high-risk human papillomaviruses (HPVs), a novel HPV-67 and HPV-31 from bowenoid papulosis. (10971337)
2000
20
Facial bowenoid papulosis secondary to human papillomavirus type 16. (10233343)
1999
21
Bowenoid papulosis showing polyclonal nature. (9785012)
1998
22
Bowenoid papulosis turning to squamous cell carcinoma. (20921709)
1998
23
Bowen's disease and Bowenoid papulosis of the vulva. (7789604)
1995
24
The presence of HPV types 6/11, 13, 16 and 33 in bowenoid papulosis in an HIV-positive male, demonstrated by DNA in situ hybridization. (1648931)
1991
25
Bowenoid papulosis. (1848870)
1991
26
Linear bowenoid papulosis of the genitalia. A possible Koebner phenomenon. (2397968)
1990
27
Bowenoid papulosis. (2182038)
1990
28
Efficacy of interferons on bowenoid papulosis and other precancerous lesions. (1701802)
1990
29
Cervical intraepithelial neoplasia III in an adolescent with Bowenoid papulosis. (2175743)
1990
30
Human papillomavirus infection and filaggrin expression in paraffin-embedded biopsy specimens of extragenital Bowen's disease and genital bowenoid papulosis. (2164515)
1990
31
Detection of human papillomavirus type 16 DNA and papillomavirus genus-specific antigens in vulva and cervix from patients with Bowenoid papulosis. (2540130)
1989
32
Bowenoid papulosis of the penis: successful management with neodymium:YAG laser. (3373609)
1988
33
Detection of human papillomavirus type 16 in bowenoid papulosis and invasive carcinoma occurring in the same patient with a history of cervical carcinoma. (2837151)
1988
34
Bowenoid papulosis. (3026758)
1987
35
Human papillomavirus type 16 in bowenoid papulosis, intraoral papillomas, and squamous cell carcinoma of the tongue. (3028282)
1987
36
Bowenoid papulosis: clinical and histological study of eight cases. (3034760)
1987
37
Bowenoid papulosis in a penile epidermal inclusion cyst. (3828216)
1987
38
Bowenoid papulosis of the male and female genitalia: risk of cervical neoplasia. (3007587)
1986
39
Bowenoid papulosis in three-year-old girl. (3950132)
1986
40
Bowenoid papulosis of the genitalia associated with human papillomavirus DNA type 16 in an infant with atopic dermatitis. (2989808)
1985
41
HPV-16-related Bowenoid papulosis. (2861521)
1985
42
Papillomavirus common antigens. Papillomavirus antigen in verruca, benign papillomatous lesions, trichilemmoma, and bowenoid papulosis: an immunoperoxidase study. (6329106)
1984
43
Bowenoid papulosis of the chin. (6491022)
1984
44
Human papillomavirus type-16-related DNA in genital Bowen's disease and in Bowenoid papulosis. (6315601)
1983
45
Bowenoid papulosis in the perianal region. (6593959)
1983
46
Etretinate in bowenoid papulosis. (6118745)
1981
47
Bowenoid papulosis: a review. (7009074)
1981
48
Bowenoid papulosis of the penis. (7398133)
1980
49
Bowenoid papulosis of the penis. Demonstration of intranuclear viral-like particles. (7468932)
1980
50
Bowenoid papulosis. (549498)
1979

Variations for Bowenoid Papulosis

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Expression for genes affiliated with Bowenoid Papulosis

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Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for genes affiliated with Bowenoid Papulosis

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Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 24)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6CCND1, CCNE1
29.6CCND1, CCNE1
3
Show member pathways
9.6CCND1, CCNE1
49.6CCND1, CCNE1
59.5CCND1, CDKN2A
69.5CCNE1, TERT
79.4CCND1, PPARG
89.4CCNE1, PPARG
9
Show member pathways
9.1CCND1, CCNE1, CDKN2A
10
Show member pathways
9.1CCND1, CCNE1, CDKN2A
119.1CCND1, CCNE1, CDKN2A
129.1CCND1, CCNE1, CDKN2A
13
Show member pathways
9.1CCND1, CCNE1, CDKN2A
149.1CCND1, CCNE1, CDKN2A
15
Show member pathways
9.1CCND1, CCNE1, CDKN2A
169.1CCND1, CCNE1, CDKN2A
17
Show member pathways
9.1CCND1, CCNE1, CDKN2A
189.0PPARG, PTGS2
199.0CCND1, CDKN2A, TERT
208.8CCND1, CCNE1, PTGS2
218.8CCND1, CCNE1, PTGS2
22
Show member pathways
8.6CCND1, PPARG, PTGS2
238.3CCND1, CCNE1, CDKN2A, PTGS2
247.6CCND1, CCNE1, CDKN2A, PPARG, PTGS2

GO Terms for genes affiliated with Bowenoid Papulosis

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Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein kinase holoenzyme complexGO:000030710.2CCND1, CCNE1
2nucleusGO:00056346.7CCND1, CCNE1, CDKN2A, FLG, PPARG, PTGS2

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1response to vitamin EGO:003319710.1CCND1, CCNE1
2response to corticosteroneGO:005141210.1CCND1, CCNE1
3response to steroid hormoneGO:004854510.1CCND1, CCNE1
4replicative senescenceGO:009039910.0CDKN2A, TERT
5fat cell differentiationGO:004544410.0CCND1, PPARG
6brown fat cell differentiationGO:00508739.6PPARG, PTGS2
7regulation of blood pressureGO:00082179.4PPARG, PTGS2
8G1/S transition of mitotic cell cycleGO:00000829.3CCND1, CCNE1, CDKN2A
9organ regenerationGO:00311009.3CCND1, CCNE1, PPARG
10mitotic cell cycleGO:00002789.2CCND1, CCNE1, CDKN2A
11response to organonitrogen compoundGO:00102439.2CCND1, CCNE1, PTGS2
12response to cytokineGO:00340978.9CCNE1, PTGS2
13positive regulation of apoptotic processGO:00430658.8CDKN2A, PPARG, PTGS2
14response to estradiolGO:00323558.8CCND1, CCNE1, PTGS2
15negative regulation of cell proliferationGO:00082858.8CDKN2A, PPARG, PTGS2
16response to organic substanceGO:00100338.6CCND1, PPARG, PTGS2
17response to organic cyclic compoundGO:00140708.6CCND1, CCNE1, PPARG, PTGS2
18response to drugGO:00424938.1CCND1, CCNE1, PPARG, PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase regulator activityGO:001653810.0CCND1, CCNE1
2protein kinase bindingGO:00199019.4CCND1, CCNE1, CDKN2A
3transcription factor bindingGO:00081349.1CCND1, CDKN2A, PPARG
4kinase activityGO:00163019.1CCND1, CCNE1, CDKN2A
5enzyme bindingGO:00198998.8CCND1, PPARG, PTGS2

Sources for Bowenoid Papulosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet