BP
MCID: BWN003
MIFTS: 29

Bowenoid Papulosis (BP) malady

Summaries for Bowenoid Papulosis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

MalaCards: Bowenoid Papulosis, also known as BP, is related to squamous cell carcinoma and papilloma. An important gene associated with Bowenoid Papulosis is FLG (filaggrin), and among its related pathways are Celecoxib Pathway, Pharmacodynamics and Apoptotic Pathways in Synovial Fibroblasts. The compounds nickel and depsipeptide have been mentioned in the context of this disorder. Related mouse phenotypes are homeostasis/metabolism and integument.

Aliases & Classifications for Bowenoid Papulosis

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42NIH Rare Diseases, 60UMLS
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Aliases & Descriptions:

bowenoid papulosis 42 60
bp 42


Related Diseases for Bowenoid Papulosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to bowenoid papulosis

Clinical Features for Bowenoid Papulosis

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Drugs & Therapeutics for Bowenoid Papulosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Bowenoid Papulosis

Drug clinical trials:

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Search NIH Clinical Center for Bowenoid Papulosis

Search CenterWatch for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

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Anatomical Context for Bowenoid Papulosis

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Animal Models for Bowenoid Papulosis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Bowenoid Papulosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537610.1FLG
2MP:00107719.2CDKN2A, PTGS2
3MP:00053898.8PTGS2, TERT, CDKN2A
4MP:00020068.2PPARG, CDKN2A, TERT, PTGS2
5MP:00053798.0PTGS2, TERT, CDKN2A, PPARG
6MP:00053977.8PTGS2, TERT, CDKN2A, FLG, PPARG
7MP:00053877.7PPARG, FLG, CDKN2A, TERT, PTGS2
8MP:00053847.7PTGS2, TERT, CDKN2A, FLG, PPARG
9MP:00053787.6PPARG, FLG, CDKN2A, TERT, PTGS2
10MP:00107687.2PTGS2, TERT, CDKN2A, FLG, PPARG

Publications for Bowenoid Papulosis

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Genetic Variations for Bowenoid Papulosis

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Expression for genes affiliated with Bowenoid Papulosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bowenoid Papulosis

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Pathways for genes affiliated with Bowenoid Papulosis

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49PharmGKB, 51QIAGEN, 29KEGG
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Pathways related to Bowenoid Papulosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1PTGS2, PPARG
2
Hide members
8.5TERT, CDKN2A, PPARG
38.5PTGS2, CDKN2A, PPARG

Compounds for genes affiliated with Bowenoid Papulosis

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Sources:
44Novoseek, 24HMDB, 28IUPHAR, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Bowenoid Papulosis according to GeneCards/GeneDecks:

(show all 39)
idCompoundScoreTop Affiliating Genes
1nickel44 2411.3FLG
2depsipeptide4410.1CDKN2A
3hematoxylin4410.0CDKN2A
4salicylic acid44 2810.6PTGS2, FLG
5indomethacine449.6PTGS2, PPARG
6balsalazide44 1110.5PTGS2, PPARG
7Mesalazine119.5PPARG, PTGS2
8Icosapent119.5PTGS2, PPARG
9cyclopentenone449.5PPARG, PTGS2
10nimesulide44 1110.5PPARG, PTGS2
11exisulind449.5PPARG, PTGS2
12gw966244 2810.5PTGS2, PPARG
13rofecoxib44 49 28 1112.5PTGS2, PPARG
14sulindac sulfide449.5PTGS2, PPARG
15ciglitazone44 2810.5PPARG, PTGS2
16sulfasalazine44 28 49 1112.4PTGS2, PPARG
17sulindac44 1110.4PTGS2, PPARG
18ndga449.4PPARG, PTGS2
19pgd2449.4PTGS2, PPARG
20diclofenac44 28 49 1112.4PTGS2, PPARG
21ibuprofen44 28 49 11 2413.3PPARG, PTGS2
2215-deoxy-delta-12,14-prostaglandin j2449.2PPARG, PTGS2
23irinotecan44 49 1111.2CDKN2A, PTGS2
24egcg449.2CDKN2A, TERT, PTGS2
25celecoxib44 59 28 49 11 2414.2PTGS2, PPARG
26pioglitazone44 49 28 1112.1PTGS2, PPARG
27gf 109203x44 5910.1PTGS2, FLG, PPARG
28cisplatin44 49 59 1112.1CDKN2A, TERT, PTGS2
29ly294002449.0PPARG, TERT, PTGS2
30pdtc448.8PPARG, PTGS2
31nitric oxide44 11 2410.7PTGS2, TERT, CDKN2A, FLG
32cycloheximide448.7PTGS2, CDKN2A, PPARG
33testosterone44 59 11 2411.5TERT, CDKN2A, PPARG
34n acetylcysteine448.4PTGS2, TERT, CDKN2A, PPARG
35retinoic acid44 249.4PPARG, FLG, CDKN2A, TERT
36genistein44 28 59 2 11 2413.4PPARG, CDKN2A, TERT, PTGS2
37lipid448.4TERT, CDKN2A, FLG, PPARG
38vegf448.4PPARG, CDKN2A, TERT, PTGS2
39estrogen448.4PPARG, CDKN2A, TERT, PTGS2

GO Terms for genes affiliated with Bowenoid Papulosis

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16Gene Ontology
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Biological processes related to Bowenoid Papulosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1replicative senescenceGO:0903999.3TERT, CDKN2A
2activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.0CDKN2A, PPARG
3brown fat cell differentiationGO:0508739.0PTGS2, PPARG
4regulation of blood pressureGO:0082178.8PTGS2, PPARG

Products for genes affiliated with Bowenoid Papulosis

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Sources for Bowenoid Papulosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet