MCID: BWN003
MIFTS: 37

Bowenoid Papulosis

Categories: Rare diseases

Aliases & Classifications for Bowenoid Papulosis

MalaCards integrated aliases for Bowenoid Papulosis:

Name: Bowenoid Papulosis 49 69
Bp 49

Classifications:



External Ids:

UMLS 69 C0334106

Summaries for Bowenoid Papulosis

MalaCards based summary : Bowenoid Papulosis, also known as bp, is related to squamous cell carcinoma and cervical intraepithelial neoplasia. An important gene associated with Bowenoid Papulosis is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways/superpathways are Endometrial cancer and PI3K-Akt signaling pathway. Affiliated tissues include tongue, cervix and skin, and related phenotypes are cellular and endocrine/exocrine gland

Wikipedia : 72 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

Related Diseases for Bowenoid Papulosis

Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 30.5 CCND1 CDKN2A PTGS2
2 cervical intraepithelial neoplasia 30.1 CDKN2A TERT
3 papilloma 30.1 CCND1 CDKN2A FLG
4 interstitial cystitis 11.9
5 bowen's disease 10.5
6 breast papillomatosis 10.3 CCND1 CDKN2A
7 tonsil squamous cell carcinoma 10.3 CCND1 CDKN2A
8 endometrial squamous cell carcinoma 10.3 CCND1 CDKN2A
9 ischemic fasciitis 10.3 CCND1 CDKN2A
10 pre-malignant neoplasm 10.3 CCND1 CDKN2A
11 chondromyxoid fibroma 10.3 CCND1 CDKN2A
12 cervicitis 10.3
13 penile cancer 10.3 CCND1 CDKN2A
14 clear cell adenocarcinoma of the ovary 10.3 CCND1 CCNE1
15 retinal cancer 10.2 CCND1 CDKN2A
16 pharynx cancer 10.2 CCND1 CDKN2A
17 cervical adenosquamous carcinoma 10.2 CDKN2A PTGS2
18 bladder squamous cell carcinoma 10.2 CDKN2A PTGS2
19 esophagus adenocarcinoma 10.2 CDKN2A PTGS2
20 sensory system cancer 10.2 CCND1 CDKN2A
21 ocular cancer 10.2 CCND1 CDKN2A
22 barrett's adenocarcinoma 10.2 CDKN2A PTGS2
23 epstein-barr virus-associated gastric carcinoma 10.2 CDKN2A FLG
24 cell type benign neoplasm 10.2 CCND1 CDKN2A
25 keratocystic odontogenic tumor 10.2 CCND1 PTGS2
26 acral lentiginous melanoma 10.2 CDKN2A TERT
27 intestinal benign neoplasm 10.2 CCND1 PTGS2
28 actinic keratosis 10.1 CDKN2A PTGS2
29 cervical adenocarcinoma 10.1 CDKN2A PTGS2
30 popliteal pterygium syndrome, lethal type 10.1
31 mucositis 10.1
32 acquired immunodeficiency syndrome 10.1
33 female reproductive organ cancer 10.1 CCND1 CDKN2A
34 nervous system cancer 10.1 CCND1 CDKN2A
35 skin melanoma 10.1 CDKN2A PTGS2
36 purulent endophthalmitis 10.1 CCNE1 TERT
37 ductal carcinoma in situ 10.1 CCND1 PTGS2
38 bile duct carcinoma 10.0 CCND1 PTGS2
39 systemic lupus erythematosus 10.0
40 suppressor of tumorigenicity 3 10.0
41 dermatitis, atopic 10.0
42 leukemia 10.0
43 skin epithelioid hemangioma 10.0
44 dermatitis 10.0
45 hairy cell leukemia 10.0
46 in situ carcinoma 10.0
47 lupus erythematosus 10.0
48 cervix uteri carcinoma in situ 10.0
49 balanitis xerotica obliterans 10.0 CCND1 CDKN2A PTGS2
50 gastrointestinal system benign neoplasm 10.0 CCND1 CDKN2A PTGS2

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to Bowenoid Papulosis

Symptoms & Phenotypes for Bowenoid Papulosis

MGI Mouse Phenotypes related to Bowenoid Papulosis:

43 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.99 PTGS2 CDKN2A CCND1 PPARG CCNE1 TERT
2 endocrine/exocrine gland MP:0005379 9.95 CDKN2A CCND1 PPARG CCNE1 PTGS2 TERT
3 growth/size/body region MP:0005378 9.93 CDKN2A CCND1 PPARG CCNE1 PTGS2 TERT
4 hematopoietic system MP:0005397 9.91 CDKN2A CCND1 PPARG CCNE1 PTGS2 TERT
5 digestive/alimentary MP:0005381 9.89 CDKN2A CCND1 CCNE1 PTGS2 TERT
6 immune system MP:0005387 9.88 PTGS2 CDKN2A CCND1 PPARG CCNE1 TERT
7 neoplasm MP:0002006 9.8 CCND1 PPARG CCNE1 PTGS2 CDKN2A TERT
8 integument MP:0010771 9.77 CDKN2A CCND1 PPARG CCNE1 PTGS2
9 nervous system MP:0003631 9.73 PTGS2 CDKN2A CCND1 PPARG CCNE1 TERT
10 normal MP:0002873 9.55 CCND1 PPARG CCNE1 PTGS2 TERT
11 reproductive system MP:0005389 9.43 CDKN2A CCND1 PPARG CCNE1 PTGS2 TERT
12 skeleton MP:0005390 9.1 CDKN2A CCND1 PPARG CCNE1 PTGS2 TERT

Drugs & Therapeutics for Bowenoid Papulosis

Search Clinical Trials , NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

Anatomical Context for Bowenoid Papulosis

MalaCards organs/tissues related to Bowenoid Papulosis:

38
Tongue, Cervix, Skin

Publications for Bowenoid Papulosis

Articles related to Bowenoid Papulosis:

(show top 50) (show all 141)
# Title Authors Year
1
Vulvar Bowenoid Papulosis: Histologically High-Grade Squamous Intraepithelial Lesion Known to Spontaneously Regress. ( 28452867 )
2017
2
Bowenoid papulosis in a linear distribution. ( 27279825 )
2016
3
Aminolevulinic acid photodynamic therapy for bowenoid papulosis. ( 25751357 )
2015
4
Bowenoid papulosis. ( 26692627 )
2015
5
High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review. ( 26693089 )
2015
6
Dramatic clearance of HIV-associated bowenoid papulosis using combined oral acitretin and topical 5% imiquimod. ( 25116965 )
2014
7
Dermoscopic findings in bowenoid papulosis: report of two cases. ( 25396088 )
2014
8
A case of isolated bowenoid papulosis of the nipple. ( 24966640 )
2014
9
Bowenoid papulosis successfully treated with imiquimod 5% cream. ( 24909216 )
2014
10
Expression of cyclin D1 and cyclin E significantly associates with human papillomavirus subtypes in Bowenoid papulosis. ( 23044415 )
2013
11
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. ( 23347880 )
2013
12
Expression of activation-induced cytidine deaminase in Bowenoid papulosis. ( 24126385 )
2013
13
Whither bowenoid papulosis? ( 23336842 )
2013
14
Expression of p16 protein in lesional and perilesional condyloma acuminata and bowenoid papulosis: clinical significance and diagnostic implications. ( 23706650 )
2013
15
Periungual bowenoid papulosis due to human papillomavirus type 42. ( 23375694 )
2013
16
Bowenoid papulosis and invasive Bowen's disease: a multidisciplinary approach. ( 22717936 )
2013
17
Spontaneous regression of bowenoid papulosis. ( 24011282 )
2013
18
A combined assay of hTERT and E6 oncoprotein to identify virus-infected keratinocytes with higher telomerase activity in human papillomaviruses 16 and 18-related bowenoid papulosis. ( 22688392 )
2012
19
Successful treatment with fluoropyrimidine TS-1 of human papillomavirus type 16-detected multiple oral bowenoid papulosis in an elderly woman. ( 22266463 )
2012
20
Coexistence of Bowenoid papulosis and Bowen's disease in a patient with systemic lupus erythematosus. ( 22142328 )
2012
21
Multiple linear bowenoid papulosis without surrounding papules. ( 22221073 )
2012
22
Bowenoid Papulosis of the Vulva and Subsequent Periungual Bowen's Disease Induced by the Same Mucosal HPVs. ( 22148018 )
2011
23
Detection of human papillomavirus type 67 from bowenoid papulosis. ( 20974556 )
2010
24
What is your diagnosis? Bowenoid papulosis. ( 21284277 )
2010
25
Topical treatment of bowenoid papulosis of the penis with imiquimod. ( 19207667 )
2009
26
Isolated extragenital bowenoid papulosis of the toe-webs. ( 19326023 )
2009
27
[The expressions of PPAR-gamma, COX-2 in the lesions of patients with condyloma acuminatum and bowenoid papulosis]. ( 19627000 )
2009
28
Spontaneous regression of bowenoid papulosis in a patient with acquired immunodeficiency syndrome after an increase in peripheral CD4+ T lymphocytes. ( 19200210 )
2009
29
Bowenoid papulosis of the genitalia successfully treated with topical tazarotene: a report of two cases. ( 20161865 )
2009
30
Increased human papillomavirus type 31 DNA load in a verrucous high-grade intraepithelial neoplasia of a human immunodeficiency virus-infected patient with extensive bowenoid papulosis. ( 17300265 )
2007
31
Differences in imiquimod treatment outcome in two patients with bowenoid papulosis containing either episomal or integrated human papillomavirus 16. ( 17008876 )
2007
32
Angiolymphoid hyperplasia with eosinophilia mimicking Bowenoid papulosis. ( 17263828 )
2007
33
P16(INK4A) expression in Bowen's disease and Bowenoid papulosis. ( 17100385 )
2006
34
Oral bowenoid papulosis in an HIV-positive male. ( 16504866 )
2006
35
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. ( 16700665 )
2006
36
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis. ( 16919029 )
2006
37
Oral bowenoid papulosis in an HIV-positive male. ( 16997106 )
2006
38
A case of Bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%. ( 15601490 )
2004
39
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. ( 14731252 )
2004
40
Bowenoid papulosis at the site of prior herpes progenitalis. ( 15538089 )
2004
41
Bowenoid papulosis in a patient with AIDS treated with imiquimod: case report. ( 15588562 )
2004
42
Human papillomavirus-32-positive extragenital Bowenoid papulosis (BP) in a HIV patient with typical genital BP localization. ( 15389001 )
2004
43
Elevated amount of human papillomavirus 31 DNA in a squamous cell carcinoma developed from bowenoid papulosis. ( 15539898 )
2004
44
Bowenoid papulosis. ( 12545128 )
2003
45
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device. ( 14674917 )
2003
46
Bowenoid papulosis successfully treated with imiquimod. ( 12702095 )
2003
47
Detection of human papillomavirus type 16 in bowenoid papulosis and nonbowenoid tissues. ( 12786880 )
2003
48
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus. ( 12837910 )
2003
49
Bowenoid papulosis of the vulva-immunotherapeutical approach with topical imiquimod. ( 14504882 )
2003
50
A cardiac allograft recipient with Bowen's disease on a finger and concurrent perianal bowenoid papulosis. ( 12773804 )
2003

Variations for Bowenoid Papulosis

Expression for Bowenoid Papulosis

Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for Bowenoid Papulosis

Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 33)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.74 CCND1 CCNE1 CDKN2A PPARG
2
Show member pathways
12.6 CCND1 CCNE1 PTGS2 TERT
3
Show member pathways
12.34 CCND1 CCNE1 CDKN2A TERT
4
Show member pathways
12.31 CCND1 CCNE1 PTGS2
5
Show member pathways
12.3 CCND1 CCNE1 CDKN2A
6 12.24 CCND1 CCNE1 CDKN2A
7 12.16 CCND1 CCNE1 PTGS2
8 12.16 CCND1 CDKN2A TERT
9
Show member pathways
12.09 CCND1 CCNE1 CDKN2A
10 12.07 CCND1 CCNE1 CDKN2A
11
Show member pathways
12.05 CCND1 CCNE1 CDKN2A
12
Show member pathways
12.01 CCND1 PPARG PTGS2
13 11.97 CCND1 CCNE1 CDKN2A
14 11.93 CCND1 CCNE1 CDKN2A PTGS2
15
Show member pathways
11.88 CCND1 CCNE1 CDKN2A
16 11.82 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
17 11.81 CCND1 CCNE1 CDKN2A
18 11.7 CCND1 CCNE1 CDKN2A
19
Show member pathways
11.57 CCND1 CCNE1
20 11.54 CCND1 CCNE1 CDKN2A
21 11.52 CCND1 CDKN2A
22
Show member pathways
11.5 CCND1 CCNE1
23 11.47 CCND1 TERT
24
Show member pathways
11.45 CCND1 PTGS2
25 11.41 PPARG PTGS2
26 11.4 CCND1 CCNE1 PTGS2
27 11.38 CCNE1 PPARG
28 11.35 CCND1 PPARG
29 11.33 CCND1 PTGS2
30 11.32 CCND1 CCNE1
31 11.24 CCND1 CCNE1
32 11.07 CCND1 CCNE1
33 10.84 CCND1 CCNE1 CDKN2A

GO Terms for Bowenoid Papulosis

Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.5 CCND1 CCNE1 CDKN2A FLG PPARG PTGS2
2 cyclin-dependent protein kinase holoenzyme complex GO:0000307 8.62 CCND1 CCNE1

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 9.65 CDKN2A PPARG PTGS2
2 response to drug GO:0042493 9.61 CCND1 PPARG PTGS2
3 regulation of protein stability GO:0031647 9.54 CDKN2A TERT
4 regulation of blood pressure GO:0008217 9.52 PPARG PTGS2
5 response to estrogen GO:0043627 9.51 CCND1 PPARG
6 response to glucocorticoid GO:0051384 9.49 CCND1 PTGS2
7 regulation of protein kinase activity GO:0045859 9.46 CCND1 CCNE1
8 animal organ regeneration GO:0031100 9.4 CCND1 PPARG
9 telomere maintenance GO:0000723 9.37 CCNE1 TERT
10 response to organic cyclic compound GO:0014070 9.33 CCND1 PPARG PTGS2
11 response to organonitrogen compound GO:0010243 9.32 CCND1 PTGS2
12 replicative senescence GO:0090399 9.26 CDKN2A TERT
13 G1/S transition of mitotic cell cycle GO:0000082 9.13 CCND1 CCNE1 CDKN2A
14 response to organic substance GO:0010033 8.8 CCND1 PPARG PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 9.43 CCND1 CCNE1 CDKN2A
2 enzyme binding GO:0019899 9.33 CCND1 PPARG PTGS2
3 transcription factor binding GO:0008134 9.13 CCND1 CDKN2A PPARG
4 cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 8.62 CCND1 CCNE1

Sources for Bowenoid Papulosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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