MCID: BWN003
MIFTS: 33

Bowenoid Papulosis

Categories: Rare diseases

Aliases & Classifications for Bowenoid Papulosis

MalaCards integrated aliases for Bowenoid Papulosis:

Name: Bowenoid Papulosis 50 69
Bp 50

Classifications:



Summaries for Bowenoid Papulosis

MalaCards based summary : Bowenoid Papulosis, also known as bp, is related to interstitial cystitis and popliteal pterygium syndrome, bartsocas-papas type. An important gene associated with Bowenoid Papulosis is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways/superpathways are Mitotic G1-G1/S phases and PI3K-Akt signaling pathway. Affiliated tissues include tongue, cervix and skin, and related phenotypes are cellular and endocrine/exocrine gland

Wikipedia : 72 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

Related Diseases for Bowenoid Papulosis

Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
id Related Disease Score Top Affiliating Genes
1 interstitial cystitis 11.7
2 popliteal pterygium syndrome, bartsocas-papas type 10.9
3 bart-pumphrey syndrome 10.8
4 d-bifunctional protein deficiency 10.8
5 growth hormone insensitivity with immunodeficiency 10.8
6 vertebrobasilar insufficiency 10.8
7 bipolar i disorder 10.8
8 skeletal tuberculosis 10.5 CCND1 CDKN2A
9 sarcomatoid squamous cell skin carcinoma 10.5 CCND1 CDKN2A
10 neurofibroma of the esophagus 10.5 CCND1 CDKN2A
11 bladder squamous cell carcinoma 10.5 CCND1 CDKN2A
12 bowen's disease 10.4
13 ductal carcinoma in situ 10.4 CCND1 CDKN2A
14 angelman syndrome due to imprinting defect in 15q11-q13 10.4 CCND1 CDKN2A
15 squamous cell carcinoma 10.4
16 unilateral retinoblastoma 10.4 CCND1 CDKN2A
17 rete testis neoplasm 10.4 CDKN2A PTGS2
18 villous adenocarcinoma 10.4 CDKN2A PTGS2
19 integumentary system cancer 10.4 CCND1 CDKN2A
20 esophagus squamous cell carcinoma 10.4 CDKN2A PTGS2
21 pharynx cancer 10.3 CCND1 CDKN2A
22 schwannian stroma-rich and stroma-poor composite ganglioneuroblastoma 10.3 CDKN2A PTGS2
23 autosomal recessive leukoencephalopathy-ischemic stroke-retinitis pigmentosa syndrome 10.3 CDKN2A FLG
24 post-surgical hypoinsulinemia 10.3 CCND1 CDKN2A
25 oral antidiabetic drugs toxicity or dose selection 10.3 CCND1 PTGS2
26 male reproductive organ benign neoplasm 10.3 CCND1 CDKN2A
27 diffuse meningeal melanocytosis 10.3 CDKN2A TERT
28 maxillary neoplasm 10.2 CCND1 PTGS2
29 fasciolopsiasis 10.2 CDKN2A PTGS2
30 fallopian tube mucinous tumor 10.2 CDKN2A PTGS2
31 rare endometriosis 10.2 CDKN2A TERT
32 cervicitis 10.2
33 charcot-marie-tooth disease type 2a 10.2 CDKN2A TERT
34 acute allergic mucoid otitis media 10.2 CCNE1 TERT
35 trachea squamous cell carcinoma 10.1 CCND1 CDKN2A
36 atrophic gastritis 10.1 CDKN2A PTGS2
37 bullous pemphigoid 10.1
38 urethra adenocarcinoma 10.0 CCND1 PTGS2
39 mucositis 10.0
40 papilloma 10.0
41 acquired immunodeficiency syndrome 10.0
42 active vestibular meniere's disease 10.0 CCND1 CDKN2A PTGS2
43 gastrointestinal neuroendocrine tumor 10.0 CCND1 CDKN2A PTGS2
44 estrogen-receptor negative breast cancer 10.0 CCND1 CDKN2A PTGS2
45 orbital lymphangioma 10.0 CCND1 CDKN2A PTGS2
46 farber lipogranulomatosis 10.0 CCND1 CDKN2A PTGS2
47 gallbladder cancer 10.0 CCND1 CDKN2A PTGS2
48 villous adenoma 10.0 CCND1 CDKN2A PTGS2
49 acute porphyria 10.0 CCND1 CDKN2A PTGS2
50 gastric cancer, somatic 10.0 CCND1 CDKN2A PTGS2

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to Bowenoid Papulosis

Symptoms & Phenotypes for Bowenoid Papulosis

MGI Mouse Phenotypes related to Bowenoid Papulosis:

44 (show all 12)
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.99 CCNE1 PTGS2 CDKN2A CCND1 PPARG TERT
2 endocrine/exocrine gland MP:0005379 9.95 PTGS2 CDKN2A CCND1 PPARG CCNE1 TERT
3 growth/size/body region MP:0005378 9.93 PPARG CCNE1 CDKN2A CCND1 PTGS2 TERT
4 hematopoietic system MP:0005397 9.91 CCNE1 PTGS2 CDKN2A CCND1 PPARG TERT
5 digestive/alimentary MP:0005381 9.89 PTGS2 CDKN2A CCND1 CCNE1 TERT
6 immune system MP:0005387 9.88 CCNE1 PTGS2 CDKN2A CCND1 PPARG TERT
7 neoplasm MP:0002006 9.8 PTGS2 CDKN2A CCND1 PPARG CCNE1 TERT
8 integument MP:0010771 9.77 CCNE1 PTGS2 CDKN2A CCND1 PPARG
9 nervous system MP:0003631 9.73 CCNE1 PTGS2 CDKN2A CCND1 PPARG TERT
10 normal MP:0002873 9.55 CCNE1 CCND1 PPARG PTGS2 TERT
11 reproductive system MP:0005389 9.43 PTGS2 CDKN2A CCND1 PPARG CCNE1 TERT
12 skeleton MP:0005390 9.1 PTGS2 CDKN2A CCND1 PPARG CCNE1 TERT

Drugs & Therapeutics for Bowenoid Papulosis

Search Clinical Trials , NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

Anatomical Context for Bowenoid Papulosis

MalaCards organs/tissues related to Bowenoid Papulosis:

39
Tongue, Cervix, Skin

Publications for Bowenoid Papulosis

Articles related to Bowenoid Papulosis:

(show top 50) (show all 141)
id Title Authors Year
1
Vulvar Bowenoid Papulosis: Histologically High-Grade Squamous Intraepithelial Lesion Known to Spontaneously Regress. ( 28452867 )
2017
2
Bowenoid papulosis in a linear distribution. ( 27279825 )
2016
3
Bowenoid papulosis. ( 26692627 )
2015
4
Aminolevulinic acid photodynamic therapy for bowenoid papulosis. ( 25751357 )
2015
5
High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review. ( 26693089 )
2015
6
Bowenoid papulosis successfully treated with imiquimod 5% cream. ( 24909216 )
2014
7
Dramatic clearance of HIV-associated bowenoid papulosis using combined oral acitretin and topical 5% imiquimod. ( 25116965 )
2014
8
Dermoscopic findings in bowenoid papulosis: report of two cases. ( 25396088 )
2014
9
A case of isolated bowenoid papulosis of the nipple. ( 24966640 )
2014
10
Expression of cyclin D1 and cyclin E significantly associates with human papillomavirus subtypes in Bowenoid papulosis. ( 23044415 )
2013
11
Spontaneous regression of bowenoid papulosis. ( 24011282 )
2013
12
Expression of activation-induced cytidine deaminase in Bowenoid papulosis. ( 24126385 )
2013
13
Expression of p16 protein in lesional and perilesional condyloma acuminata and bowenoid papulosis: clinical significance and diagnostic implications. ( 23706650 )
2013
14
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. ( 23347880 )
2013
15
Periungual bowenoid papulosis due to human papillomavirus type 42. ( 23375694 )
2013
16
Bowenoid papulosis and invasive Bowen's disease: a multidisciplinary approach. ( 22717936 )
2013
17
Whither bowenoid papulosis? ( 23336842 )
2013
18
Coexistence of Bowenoid papulosis and Bowen's disease in a patient with systemic lupus erythematosus. ( 22142328 )
2012
19
A combined assay of hTERT and E6 oncoprotein to identify virus-infected keratinocytes with higher telomerase activity in human papillomaviruses 16 and 18-related bowenoid papulosis. ( 22688392 )
2012
20
Multiple linear bowenoid papulosis without surrounding papules. ( 22221073 )
2012
21
Successful treatment with fluoropyrimidine TS-1 of human papillomavirus type 16-detected multiple oral bowenoid papulosis in an elderly woman. ( 22266463 )
2012
22
Bowenoid Papulosis of the Vulva and Subsequent Periungual Bowen's Disease Induced by the Same Mucosal HPVs. ( 22148018 )
2011
23
Detection of human papillomavirus type 67 from bowenoid papulosis. ( 20974556 )
2010
24
What is your diagnosis? Bowenoid papulosis. ( 21284277 )
2010
25
Spontaneous regression of bowenoid papulosis in a patient with acquired immunodeficiency syndrome after an increase in peripheral CD4+ T lymphocytes. ( 19200210 )
2009
26
Bowenoid papulosis of the genitalia successfully treated with topical tazarotene: a report of two cases. ( 20161865 )
2009
27
Isolated extragenital bowenoid papulosis of the toe-webs. ( 19326023 )
2009
28
[The expressions of PPAR-gamma, COX-2 in the lesions of patients with condyloma acuminatum and bowenoid papulosis]. ( 19627000 )
2009
29
Topical treatment of bowenoid papulosis of the penis with imiquimod. ( 19207667 )
2009
30
Angiolymphoid hyperplasia with eosinophilia mimicking Bowenoid papulosis. ( 17263828 )
2007
31
Increased human papillomavirus type 31 DNA load in a verrucous high-grade intraepithelial neoplasia of a human immunodeficiency virus-infected patient with extensive bowenoid papulosis. ( 17300265 )
2007
32
Differences in imiquimod treatment outcome in two patients with bowenoid papulosis containing either episomal or integrated human papillomavirus 16. ( 17008876 )
2007
33
Oral bowenoid papulosis in an HIV-positive male. ( 16997106 )
2006
34
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis. ( 16919029 )
2006
35
Oral bowenoid papulosis in an HIV-positive male. ( 16504866 )
2006
36
P16(INK4A) expression in Bowen's disease and Bowenoid papulosis. ( 17100385 )
2006
37
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. ( 16700665 )
2006
38
Elevated amount of human papillomavirus 31 DNA in a squamous cell carcinoma developed from bowenoid papulosis. ( 15539898 )
2004
39
Bowenoid papulosis at the site of prior herpes progenitalis. ( 15538089 )
2004
40
Bowenoid papulosis in a patient with AIDS treated with imiquimod: case report. ( 15588562 )
2004
41
Human papillomavirus-32-positive extragenital Bowenoid papulosis (BP) in a HIV patient with typical genital BP localization. ( 15389001 )
2004
42
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. ( 14731252 )
2004
43
A case of Bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%. ( 15601490 )
2004
44
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device. ( 14674917 )
2003
45
Bowenoid papulosis. ( 12545128 )
2003
46
Bowenoid papulosis successfully treated with imiquimod. ( 12702095 )
2003
47
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus. ( 12837910 )
2003
48
Detection of human papillomavirus type 16 in bowenoid papulosis and nonbowenoid tissues. ( 12786880 )
2003
49
A cardiac allograft recipient with Bowen's disease on a finger and concurrent perianal bowenoid papulosis. ( 12773804 )
2003
50
Bowenoid papulosis of the vulva-immunotherapeutical approach with topical imiquimod. ( 14504882 )
2003

Variations for Bowenoid Papulosis

Expression for Bowenoid Papulosis

Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for Bowenoid Papulosis

Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 30)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 CCND1 CCNE1 CDKN2A
2 12.27 CCND1 CCNE1 PTGS2 TERT
3
Show member pathways
12.23 CCND1 CCNE1 CDKN2A PPARG
4 12.21 CCND1 CCNE1 CDKN2A
5 12.13 CCND1 CCNE1 PTGS2
6 12.13 CCND1 CDKN2A TERT
7
Show member pathways
12.06 CCND1 CCNE1 CDKN2A
8 12.05 CCND1 CCNE1 CDKN2A
9
Show member pathways
12.02 CCND1 CCNE1 CDKN2A
10
Show member pathways
11.98 CCND1 PPARG PTGS2
11 11.94 CCND1 CCNE1 CDKN2A
12 11.93 CCND1 CCNE1 CDKN2A PTGS2
13
Show member pathways
11.83 CCND1 CCNE1 CDKN2A
14 11.67 CCND1 CCNE1 CDKN2A
15 11.62 CCND1 CCNE1 CDKN2A PPARG PTGS2
16
Show member pathways
11.55 CCND1 CCNE1
17 11.54 CCND1 CCNE1 CDKN2A
18 11.51 CCND1 CDKN2A
19
Show member pathways
11.49 CCND1 CCNE1
20 11.46 CCND1 TERT
21
Show member pathways
11.43 CCND1 PTGS2
22 11.39 PPARG PTGS2
23 11.37 CCNE1 PPARG
24 11.36 CCND1 CCNE1 PTGS2
25 11.34 CCND1 PPARG
26 11.31 CCND1 PTGS2
27 11.3 CCND1 CCNE1
28 11.23 CCND1 CCNE1
29 11.04 CCND1 CCNE1
30 10.84 CCND1 CCNE1 CDKN2A

GO Terms for Bowenoid Papulosis

Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.5 CCND1 CCNE1 CDKN2A FLG PPARG PTGS2
2 cyclin-dependent protein kinase holoenzyme complex GO:0000307 8.62 CCND1 CCNE1

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 9.65 CDKN2A PPARG PTGS2
2 response to drug GO:0042493 9.61 CCND1 PPARG PTGS2
3 regulation of protein stability GO:0031647 9.54 CDKN2A TERT
4 response to glucocorticoid GO:0051384 9.52 CCND1 PTGS2
5 regulation of blood pressure GO:0008217 9.51 PPARG PTGS2
6 response to estrogen GO:0043627 9.49 CCND1 PPARG
7 regulation of protein kinase activity GO:0045859 9.46 CCND1 CCNE1
8 response to organic cyclic compound GO:0014070 9.43 CCND1 PPARG PTGS2
9 animal organ regeneration GO:0031100 9.4 CCND1 PPARG
10 telomere maintenance GO:0000723 9.37 CCNE1 TERT
11 response to organonitrogen compound GO:0010243 9.32 CCND1 PTGS2
12 replicative senescence GO:0090399 9.16 CDKN2A TERT
13 G1/S transition of mitotic cell cycle GO:0000082 9.13 CCND1 CCNE1 CDKN2A
14 response to organic substance GO:0010033 8.8 CCND1 PPARG PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 9.43 CCND1 CCNE1 CDKN2A
2 enzyme binding GO:0019899 9.33 CCND1 PPARG PTGS2
3 transcription factor binding GO:0008134 9.13 CCND1 CDKN2A PPARG
4 cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 8.62 CCND1 CCNE1

Sources for Bowenoid Papulosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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