BP
MCID: BWN003
MIFTS: 34

Bowenoid Papulosis (BP) malady

Categories: Rare diseases

Aliases & Classifications for Bowenoid Papulosis

Aliases & Descriptions for Bowenoid Papulosis:

Name: Bowenoid Papulosis 50 69
Bp 50

Classifications:



Summaries for Bowenoid Papulosis

MalaCards based summary : Bowenoid Papulosis, also known as bp, is related to interstitial cystitis and d-bifunctional protein deficiency. An important gene associated with Bowenoid Papulosis is CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), and among its related pathways/superpathways are Mitotic G1-G1/S phases and DNA Damage. Affiliated tissues include skin, tongue and cervix, and related phenotypes are cellular and endocrine/exocrine gland

Wikipedia : 71 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

Related Diseases for Bowenoid Papulosis

Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 80)
id Related Disease Score Top Affiliating Genes
1 interstitial cystitis 11.4
2 d-bifunctional protein deficiency 10.8
3 popliteal pterygium syndrome 2, lethal type 10.8
4 bart-pumphrey syndrome 10.8
5 vertebrobasilar insufficiency 10.8
6 popliteal pterygium syndrome, bartsocas-papas type 10.8
7 bipolar i disorder 10.8
8 bowen's disease 10.4
9 squamous cell carcinoma 10.4
10 13q12.3 microdeletion syndrome 10.2 CCND1 CDKN2A
11 skeletal tuberculosis 10.2 CCND1 CDKN2A
12 anal neuroendocrine tumor 10.2 CCND1 CDKN2A
13 episodic ataxia 10.2 CCND1 CDKN2A
14 oro-mandibular-limb hypogenesis syndrome 10.2 CCND1 CDKN2A
15 brain stem medulloblastoma 10.2 CCND1 CDKN2A
16 cervical verrucous carcinoma 10.2 CCND1 CDKN2A
17 striated muscle rhabdoid tumor 10.2 CCND1 CDKN2A
18 cervicitis 10.2
19 tricuspid valve prolapse 10.1 CDKN2A PTGS2
20 acquired hemangioma 10.1 CDKN2A PTGS2
21 estrogen-receptor positive breast cancer 10.1 CCND1 CDKN2A
22 urethral verrucous carcinoma 10.1 CDKN2A PTGS2
23 pseudo-meigs syndrome 10.1 CDKN2A FLG
24 acute disseminated encephalomyelitis 10.1 CDKN2A TERT
25 tamoxifen-related endometrial lesion 10.1 CDKN2A PTGS2
26 statin toxicity 10.1 CCND1 PTGS2
27 caroli disease 10.1 CCND1 CDKN2A
28 ideomotor apraxia 10.1 CCND1 PTGS2
29 connective tissue benign neoplasm 10.1 CCND1 CDKN2A
30 bullous pemphigoid 10.0
31 pelvic varices 10.0 CCNE1 TERT
32 charcot-marie-tooth disease type 2n 10.0 CDKN2A TERT
33 papilloma 10.0
34 acquired immunodeficiency syndrome 10.0
35 mucositis 10.0
36 active vestibular meniere's disease 10.0 CCND1 CDKN2A PTGS2
37 advanced sleep phase syndrome 10.0 CCND1 CDKN2A PTGS2
38 progesterone-receptor positive breast cancer 10.0 CCND1 CDKN2A PTGS2
39 ornithinemia 10.0 CCND1 CDKN2A PTGS2
40 spinal muscular atrophy with progressive myoclonic epilepsy 10.0 CCND1 CDKN2A PTGS2
41 vestibular gland benign neoplasm 10.0 CCND1 CDKN2A PTGS2
42 nodular cutaneous amyloidosis 10.0 CDKN2A TERT
43 facial dermatosis 10.0 CCND1 CDKN2A PTGS2
44 mitochondrial encephalomyopathy 10.0 CDKN2A PTGS2
45 in situ pulmonary adenocarcinoma 10.0 CCND1 CDKN2A PTGS2
46 malignant pleural solitary fibrous tumor 10.0 CCND1 CDKN2A PTGS2
47 ovarian mucinous neoplasm 10.0 PTGS2 TERT
48 proctitis 10.0 CCND1 CDKN2A PTGS2
49 autonomic nervous system neoplasm 10.0 CCND1 CDKN2A FLG
50 hypogonadotropic hypogonadism 20 with or without anosmia 10.0 CCND1 CDKN2A PTGS2

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to Bowenoid Papulosis

Symptoms & Phenotypes for Bowenoid Papulosis

MGI Mouse Phenotypes related to Bowenoid Papulosis:

44 (show all 12)
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.99 PPARG CCND1 CCNE1 CDKN2A PTGS2 TERT
2 endocrine/exocrine gland MP:0005379 9.95 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
3 growth/size/body region MP:0005378 9.93 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
4 hematopoietic system MP:0005397 9.91 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
5 digestive/alimentary MP:0005381 9.89 PTGS2 TERT CCND1 CCNE1 CDKN2A
6 immune system MP:0005387 9.88 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
7 neoplasm MP:0002006 9.8 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
8 integument MP:0010771 9.77 CCND1 CCNE1 CDKN2A PPARG PTGS2
9 nervous system MP:0003631 9.73 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
10 normal MP:0002873 9.55 CCND1 CCNE1 PPARG PTGS2 TERT
11 reproductive system MP:0005389 9.43 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT
12 skeleton MP:0005390 9.1 CCND1 CCNE1 CDKN2A PPARG PTGS2 TERT

Drugs & Therapeutics for Bowenoid Papulosis

Search Clinical Trials , NIH Clinical Center for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

Anatomical Context for Bowenoid Papulosis

MalaCards organs/tissues related to Bowenoid Papulosis:

39
Skin, Tongue, Cervix

Publications for Bowenoid Papulosis

Articles related to Bowenoid Papulosis:

(show top 50) (show all 140)
id Title Authors Year
1
Bowenoid papulosis in a linear distribution. ( 27279825 )
2016
2
Aminolevulinic acid photodynamic therapy for bowenoid papulosis. ( 25751357 )
2015
3
Bowenoid papulosis. ( 26692627 )
2015
4
High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review. ( 26693089 )
2015
5
Dermoscopic findings in bowenoid papulosis: report of two cases. ( 25396088 )
2014
6
Dramatic clearance of HIV-associated bowenoid papulosis using combined oral acitretin and topical 5% imiquimod. ( 25116965 )
2014
7
Bowenoid papulosis successfully treated with imiquimod 5% cream. ( 24909216 )
2014
8
A case of isolated bowenoid papulosis of the nipple. ( 24966640 )
2014
9
Spontaneous regression of bowenoid papulosis. ( 24011282 )
2013
10
Bowenoid papulosis and invasive Bowen's disease: a multidisciplinary approach. ( 22717936 )
2013
11
Expression of activation-induced cytidine deaminase in Bowenoid papulosis. ( 24126385 )
2013
12
Whither bowenoid papulosis? ( 23336842 )
2013
13
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. ( 23347880 )
2013
14
Expression of p16 protein in lesional and perilesional condyloma acuminata and bowenoid papulosis: clinical significance and diagnostic implications. ( 23706650 )
2013
15
Expression of cyclin D1 and cyclin E significantly associates with human papillomavirus subtypes in Bowenoid papulosis. ( 23044415 )
2013
16
Periungual bowenoid papulosis due to human papillomavirus type 42. ( 23375694 )
2013
17
Multiple linear bowenoid papulosis without surrounding papules. ( 22221073 )
2012
18
A combined assay of hTERT and E6 oncoprotein to identify virus-infected keratinocytes with higher telomerase activity in human papillomaviruses 16 and 18-related bowenoid papulosis. ( 22688392 )
2012
19
Successful treatment with fluoropyrimidine TS-1 of human papillomavirus type 16-detected multiple oral bowenoid papulosis in an elderly woman. ( 22266463 )
2012
20
Coexistence of Bowenoid papulosis and Bowen's disease in a patient with systemic lupus erythematosus. ( 22142328 )
2012
21
Bowenoid Papulosis of the Vulva and Subsequent Periungual Bowen's Disease Induced by the Same Mucosal HPVs. ( 22148018 )
2011
22
Detection of human papillomavirus type 67 from bowenoid papulosis. ( 20974556 )
2010
23
What is your diagnosis? Bowenoid papulosis. ( 21284277 )
2010
24
Bowenoid papulosis of the genitalia successfully treated with topical tazarotene: a report of two cases. ( 20161865 )
2009
25
[The expressions of PPAR-gamma, COX-2 in the lesions of patients with condyloma acuminatum and bowenoid papulosis]. ( 19627000 )
2009
26
Topical treatment of bowenoid papulosis of the penis with imiquimod. ( 19207667 )
2009
27
Isolated extragenital bowenoid papulosis of the toe-webs. ( 19326023 )
2009
28
Spontaneous regression of bowenoid papulosis in a patient with acquired immunodeficiency syndrome after an increase in peripheral CD4+ T lymphocytes. ( 19200210 )
2009
29
Differences in imiquimod treatment outcome in two patients with bowenoid papulosis containing either episomal or integrated human papillomavirus 16. ( 17008876 )
2007
30
Angiolymphoid hyperplasia with eosinophilia mimicking Bowenoid papulosis. ( 17263828 )
2007
31
Increased human papillomavirus type 31 DNA load in a verrucous high-grade intraepithelial neoplasia of a human immunodeficiency virus-infected patient with extensive bowenoid papulosis. ( 17300265 )
2007
32
Detection of mucosal human papilloma virus DNA in bowenoid papulosis, Bowen's disease and squamous cell carcinoma of the skin. ( 16700665 )
2006
33
P16(INK4A) expression in Bowen's disease and Bowenoid papulosis. ( 17100385 )
2006
34
Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis. ( 16919029 )
2006
35
Oral bowenoid papulosis in an HIV-positive male. ( 16504866 )
2006
36
Oral bowenoid papulosis in an HIV-positive male. ( 16997106 )
2006
37
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. ( 14731252 )
2004
38
A case of Bowenoid papulosis of the penis successfully treated with topical imiquimod cream 5%. ( 15601490 )
2004
39
Elevated amount of human papillomavirus 31 DNA in a squamous cell carcinoma developed from bowenoid papulosis. ( 15539898 )
2004
40
Bowenoid papulosis at the site of prior herpes progenitalis. ( 15538089 )
2004
41
Bowenoid papulosis in a patient with AIDS treated with imiquimod: case report. ( 15588562 )
2004
42
Human papillomavirus-32-positive extragenital Bowenoid papulosis (BP) in a HIV patient with typical genital BP localization. ( 15389001 )
2004
43
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device. ( 14674917 )
2003
44
Bowenoid papulosis. ( 12545128 )
2003
45
A cardiac allograft recipient with Bowen's disease on a finger and concurrent perianal bowenoid papulosis. ( 12773804 )
2003
46
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus. ( 12837910 )
2003
47
Bowenoid papulosis successfully treated with imiquimod. ( 12702095 )
2003
48
Bowenoid papulosis of the vulva-immunotherapeutical approach with topical imiquimod. ( 14504882 )
2003
49
Detection of human papillomavirus type 16 in bowenoid papulosis and nonbowenoid tissues. ( 12786880 )
2003
50
Topical imiquimod for Bowenoid papulosis in an HIV-positive woman. ( 12353717 )
2002

Variations for Bowenoid Papulosis

Expression for Bowenoid Papulosis

Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for Bowenoid Papulosis

Pathways related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 28)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.28 CCND1 CCNE1 CDKN2A
2 12.21 CCND1 CCNE1 CDKN2A
3 12.13 CCND1 CCNE1 PTGS2
4 12.13 CCND1 CDKN2A TERT
5
Show member pathways
12.06 CCND1 CCNE1 CDKN2A
6 12.03 CCND1 CCNE1 CDKN2A
7
Show member pathways
12 CCND1 CCNE1 CDKN2A
8
Show member pathways
11.96 CCND1 PPARG PTGS2
9 11.93 CCND1 CCNE1 CDKN2A PTGS2
10 11.91 CCND1 CCNE1 CDKN2A
11
Show member pathways
11.83 CCND1 CCNE1 CDKN2A
12 11.67 CCND1 CCNE1 CDKN2A
13 11.62 CCND1 CCNE1 CDKN2A PPARG PTGS2
14
Show member pathways
11.55 CCND1 CCNE1
15 11.54 CCND1 CCNE1 CDKN2A
16
Show member pathways
11.48 CCND1 CCNE1
17 11.45 CCND1 TERT
18
Show member pathways
11.43 CCND1 PTGS2
19 11.39 PPARG PTGS2
20 11.36 CCNE1 PPARG
21 11.36 CCND1 CCNE1 PTGS2
22 11.33 CCND1 PPARG
23 11.31 CCND1 PTGS2
24 11.29 CCND1 CCNE1
25 11.22 CCND1 CCNE1
26 11.04 CCND1 CCNE1
27 10.97 CCND1 PPARG
28 10.84 CCND1 CCNE1 CDKN2A

GO Terms for Bowenoid Papulosis

Cellular components related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.5 CCND1 CCNE1 CDKN2A FLG PPARG PTGS2
2 cyclin-dependent protein kinase holoenzyme complex GO:0000307 8.62 CCND1 CCNE1

Biological processes related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.71 CDKN2A PPARG PTGS2
2 positive regulation of apoptotic process GO:0043065 9.63 CDKN2A PPARG PTGS2
3 response to drug GO:0042493 9.61 CCND1 PPARG PTGS2
4 regulation of blood pressure GO:0008217 9.52 PPARG PTGS2
5 regulation of protein stability GO:0031647 9.51 CDKN2A TERT
6 response to estrogen GO:0043627 9.49 CCND1 PPARG
7 animal organ regeneration GO:0031100 9.48 CCND1 PPARG
8 response to organic cyclic compound GO:0014070 9.43 CCND1 PPARG PTGS2
9 regulation of protein kinase activity GO:0045859 9.4 CCND1 CCNE1
10 telomere maintenance GO:0000723 9.37 CCNE1 TERT
11 response to organonitrogen compound GO:0010243 9.32 CCND1 PTGS2
12 replicative senescence GO:0090399 9.16 CDKN2A TERT
13 G1/S transition of mitotic cell cycle GO:0000082 9.13 CCND1 CCNE1 CDKN2A
14 response to organic substance GO:0010033 8.8 CCND1 PPARG PTGS2

Molecular functions related to Bowenoid Papulosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 9.43 CCND1 CCNE1 CDKN2A
2 enzyme binding GO:0019899 9.33 CCND1 PPARG PTGS2
3 transcription factor binding GO:0008134 9.13 CCND1 CDKN2A PPARG
4 cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 8.62 CCND1 CCNE1

Sources for Bowenoid Papulosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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