BP
MCID: BWN003
MIFTS: 39

Bowenoid Papulosis (BP) malady

Summaries for Bowenoid Papulosis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules... more...

MalaCards: Bowenoid Papulosis, also known as BP, is related to squamous cell carcinoma and cervical intraepithelial neoplasia. An important gene associated with Bowenoid Papulosis is FLG (filaggrin), and among its related pathways are Celecoxib Pathway, Pharmacodynamics and Apoptotic Pathways in Synovial Fibroblasts. The compounds nickel and depsipeptide have been mentioned in the context of this disorder. Affiliated tissues include skin, tongue and cervix, and related mouse phenotypes are homeostasis/metabolism and integument.

Aliases & Classifications for Bowenoid Papulosis

Sources:
43NIH Rare Diseases, 61UMLS
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Aliases & Descriptions:

bowenoid papulosis 43 61
bp 43


Related Diseases for Bowenoid Papulosis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Bowenoid Papulosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 180)
idRelated DiseaseScoreTop Affiliating Genes
1squamous cell carcinoma31.1FLG, CDKN2A, TERT, PTGS2
2cervical intraepithelial neoplasia30.3TERT, CDKN2A
3lichen planus29.7FLG
4arthritis29.7PTGS2, FLG
5oral cancer29.7PTGS2, TERT, CDKN2A
6squamous cell papilloma10.6
7bullous pemphigoid10.5
8acquired immunodeficiency syndrome10.4
9bowen syndrome10.4
10thalassemia10.3
11atopic dermatitis10.2
12systemic lupus erythematosus10.2
13verrucous papilloma10.2
14skin squamous cell carcinoma10.2
15t-cell leukemia10.2
16chronic interstitial cystitis10.2
17brain disease10.1
18coronary artery disease,10.1
19beta thalassemia10.1
20n syndrome10.1
21chronic granulomatous disease10.0
22alpha thalassemia10.0
23neurologic diseases10.0
24congenital central hypoventilation syndrome10.0
25short syndrome10.0
26central hypoventilation syndrome10.0
27hemorrhage, intracerebral10.0
28leukoplakia10.0FLG
29cholesteatoma10.0FLG
30keratosis10.0FLG
31endometriosis10.0PTGS2
32teratoma10.0TERT
33allergic rhinitis10.0FLG
34laryngeal carcinoma10.0TERT
35idiopathic pulmonary fibrosis10.0TERT
36gastritis10.0PTGS2
37uterine carcinosarcoma10.0PTGS2
38benign meningioma10.0TERT
39oligodendroglioma10.0CDKN2A
40sarcoma10.0TERT
41astrocytoma10.0CDKN2A
42multiple myeloma10.0CDKN2A
43colon adenocarcinoma10.0PTGS2
44medulloblastoma10.0TERT
45hepatitis b10.0TERT
46dermatitis10.0FLG
47tongue cancer10.0TERT
48gastrointestinal system disease10.0PTGS2
49cervical adenocarcinoma10.0CDKN2A
50pituitary tumors10.0PPARG

Graphical network of the top 20 diseases related to Bowenoid Papulosis:



Diseases related to bowenoid papulosis

Clinical Features for Bowenoid Papulosis

Drugs & Therapeutics for Bowenoid Papulosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Bowenoid Papulosis

Drug clinical trials:

Search ClinicalTrials for Bowenoid Papulosis

Search NIH Clinical Center for Bowenoid Papulosis

Search CenterWatch for Bowenoid Papulosis

Genetic Tests for Bowenoid Papulosis

Anatomical Context for Bowenoid Papulosis

Sources:
33MalaCards
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MalaCards organs/tissues related to Bowenoid Papulosis:

33
Skin, Tongue, Cervix, T cells

Animal Models for Bowenoid Papulosis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Bowenoid Papulosis

Sources:
51PubMed
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Articles related to Bowenoid Papulosis:

(show top 50)    (show all 132)
idTitleAuthorsYear
1
Extensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS. (23347880)
2013
2
Periungual bowenoid papulosis due to human papillomavirus type 42. (23375694)
2013
3
Whither bowenoid papulosis? (23336842)
2013
4
Coexistence of Bowenoid papulosis and Bowen's disease in a patient with systemic lupus erythematosus. (22142328)
2012
5
Multiple linear bowenoid papulosis without surrounding papules. (22221073)
2012
6
A combined assay of hTERT and E6 oncoprotein to identify virus-infected keratinocytes with higher telomerase activity in human papillomaviruses 16 and 18-related bowenoid papulosis. (22688392)
2012
7
Successful treatment with fluoropyrimidine TS-1 of human papillomavirus type 16-detected multiple oral bowenoid papulosis in an elderly woman. (22266463)
2012
8
Spontaneous regression of bowenoid papulosis in a patient with acquired immunodeficiency syndrome after an increase in peripheral CD4+ T lymphocytes. (19200210)
2009
9
Angiolymphoid hyperplasia with eosinophilia mimicking Bowenoid papulosis. (17263828)
2007
10
Increased human papillomavirus type 31 DNA load in a verrucous high-grade intraepithelial neoplasia of a human immunodeficiency virus-infected patient with extensive bowenoid papulosis. (17300265)
2007
11
Oral bowenoid papulosis in an HIV-positive male. (16997106)
2006
12
Morphometric assessment of nuclei in Bowen's disease and bowenoid papulosis. (14731252)
2004
13
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus. (12837910)
2003
14
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device. (14674917)
2003
15
A cardiac allograft recipient with Bowen's disease on a finger and concurrent perianal bowenoid papulosis. (12773804)
2003
16
Topical imiquimod for Bowenoid papulosis in an HIV-positive woman. (12353717)
2002
17
Extragenital bowenoid papulosis associated with atypical human papillomavirus genotypes. (11992183)
2002
18
Topical cidofovir for bowenoid papulosis in an HIV-infected patient. (11260042)
2001
19
Development of squamous cell carcinoma by two high-risk human papillomaviruses (HPVs), a novel HPV-67 and HPV-31 from bowenoid papulosis. (10971337)
2000
20
Facial bowenoid papulosis secondary to human papillomavirus type 16. (10233343)
1999
21
Heterogeneity of human papillomavirus DNA in a patient with Bowenoid papulosis that progressed to squamous cell carcinoma. (9990379)
1998
22
Bowenoid papulosis: a benign lesion of the shaft of the penis misdiagnosed as squamous carcinoma. (9120947)
1997
23
Isolated extragenital HPV-thirties-group-positive bowenoid papulosis in an AIDS patient. (7947214)
1994
24
Human papillomavirus type 16 variants isolated from vulvar Bowenoid papulosis. (8228937)
1993
25
Extra-anogenital HPV16-related bowenoid papulosis. (1655620)
1991
26
Linear bowenoid papulosis of the genitalia. A possible Koebner phenomenon. (2397968)
1990
27
Bowenoid papulosis. (2182038)
1990
28
Cervical intraepithelial neoplasia III in an adolescent with Bowenoid papulosis. (2175743)
1990
29
Human papillomavirus infection and filaggrin expression in paraffin-embedded biopsy specimens of extragenital Bowen's disease and genital bowenoid papulosis. (2164515)
1990
30
Detection of human papillomavirus type 16 DNA and papillomavirus genus-specific antigens in vulva and cervix from patients with Bowenoid papulosis. (2540130)
1989
31
Immunosuppression in men with bowenoid papulosis. (2565705)
1989
32
Virus-associated dysplasia (bowenoid papulosis?) of the oral cavity. (2549485)
1989
33
HPV 16-positive bowenoid papulosis and squamous-cell carcinoma of the anus in an HIV-positive man. (2556254)
1989
34
Bowenoid papulosis of the penis: successful management with neodymium:YAG laser. (3373609)
1988
35
Detection of human papillomavirus type 16 in bowenoid papulosis and invasive carcinoma occurring in the same patient with a history of cervical carcinoma. (2837151)
1988
36
Bowenoid papulosis. (3026758)
1987
37
Human papillomavirus type 16 in bowenoid papulosis, intraoral papillomas, and squamous cell carcinoma of the tongue. (3028282)
1987
38
Bowenoid papulosis. (18750339)
1987
39
Bowenoid papulosis of the male and female genitalia: risk of cervical neoplasia. (3007587)
1986
40
Bowenoid papulosis. Presence of human papillomavirus (HPV) structural antigens and of HPV 16-related DNA sequences. (2990353)
1985
41
Human papillomavirus type-16-related DNA in genital Bowen's disease and in Bowenoid papulosis. (6315601)
1983
42
Spontaneous regression of bowenoid papulosis of the penis. (6627990)
1983
43
Etretinate in bowenoid papulosis. (6122841)
1982
44
Bowenoid papulosis. (7174176)
1982
45
Concurrence of condylomata acuminata and bowenoid papulosis: confirmation of the hypothesis that they are related conditions. (7081629)
1982
46
Etretinate in bowenoid papulosis. (6117716)
1981
47
Viral-like particles in Bowenoid papulosis. (7325343)
1981
48
Bowenoid papulosis. (7253130)
1981
49
Bowenoid papulosis. (7217393)
1981
50
Bowenoid papulosis of the genitalia. (7369741)
1980

Genetic Variations for Bowenoid Papulosis

Expression for genes affiliated with Bowenoid Papulosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bowenoid Papulosis

Search GEO for disease gene expression data for Bowenoid Papulosis.

Pathways for genes affiliated with Bowenoid Papulosis

Sources:
50PharmGKB, 52QIAGEN, 30KEGG
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Pathways related to Bowenoid Papulosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1PTGS2, PPARG
2
Hide members
8.5TERT, CDKN2A, PPARG
38.5PTGS2, CDKN2A, PPARG

Compounds for genes affiliated with Bowenoid Papulosis

Sources:
45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank, 50PharmGKB, 60Tocris Bioscience, 2BitterDB
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Compounds related to Bowenoid Papulosis according to GeneCards/GeneDecks:

(show all 39)
idCompoundScoreTop Affiliating Genes
1nickel45 2411.3FLG
2depsipeptide4510.1CDKN2A
3hematoxylin4510.1CDKN2A
4salicylic acid45 2910.6PTGS2, FLG
5indomethacine459.6PPARG, PTGS2
6balsalazide45 1110.5PTGS2, PPARG
7Mesalazine119.5PPARG, PTGS2
8Icosapent119.5PPARG, PTGS2
9cyclopentenone459.5PPARG, PTGS2
10nimesulide45 1110.5PPARG, PTGS2
11exisulind459.5PTGS2, PPARG
12gw966245 2910.5PPARG, PTGS2
13rofecoxib45 50 29 1112.5PTGS2, PPARG
14sulindac sulfide459.5PTGS2, PPARG
15ciglitazone45 2910.5PPARG, PTGS2
16sulfasalazine45 29 50 1112.4PPARG, PTGS2
17sulindac45 1110.4PPARG, PTGS2
18ndga459.4PPARG, PTGS2
19pgd2459.4PTGS2, PPARG
20diclofenac45 29 50 1112.4PPARG, PTGS2
21ibuprofen45 29 50 11 2413.3PTGS2, PPARG
2215-deoxy-delta-12,14-prostaglandin j2459.2PTGS2, PPARG
23irinotecan45 50 1111.2PTGS2, CDKN2A
24egcg459.2CDKN2A, TERT, PTGS2
25celecoxib45 60 29 50 11 2414.2PTGS2, PPARG
26pioglitazone45 50 29 1112.1PPARG, PTGS2
27gf 109203x45 6010.1PTGS2, FLG, PPARG
28cisplatin45 50 60 1112.1PTGS2, TERT, CDKN2A
29ly294002459.0PTGS2, TERT, PPARG
30pdtc458.8PTGS2, PPARG
31nitric oxide45 11 2410.7PTGS2, FLG, TERT, CDKN2A
32cycloheximide458.7CDKN2A, PPARG, PTGS2
33testosterone45 60 11 2411.5PPARG, CDKN2A, TERT
34n acetylcysteine458.4TERT, PTGS2, CDKN2A, PPARG
35retinoic acid45 249.4FLG, TERT, CDKN2A, PPARG
36genistein45 29 60 2 11 2413.4PPARG, CDKN2A, TERT, PTGS2
37lipid458.4CDKN2A, TERT, FLG, PPARG
38vegf458.4CDKN2A, PTGS2, TERT, PPARG
39estrogen458.4PPARG, CDKN2A, TERT, PTGS2

GO Terms for genes affiliated with Bowenoid Papulosis

Sources:
16Gene Ontology
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Biological processes related to Bowenoid Papulosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1replicative senescenceGO:0903999.3TERT, CDKN2A
2activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.0CDKN2A, PPARG
3brown fat cell differentiationGO:0508739.0PTGS2, PPARG
4regulation of blood pressureGO:0082178.8PTGS2, PPARG

Products for genes affiliated with Bowenoid Papulosis

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  • Proteins
  • Lysates
  • Antibodies

Sources for Bowenoid Papulosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet