MCID: BRC010
MIFTS: 37

Brachial Plexus Lesion malady

Category: Neuronal diseases

Aliases & Classifications for Brachial Plexus Lesion

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Aliases & Descriptions for Brachial Plexus Lesion:

Name: Brachial Plexus Lesion 10 12 65
Brachial Plexus Injuries 46 35
 
Brachial Plexus Lesions Nos 10
Brachial Plexus Lesions 10

Classifications:



External Ids:

Disease Ontology10 DOID:8443
ICD9CM29 353.0
SNOMED-CT59 193109004, 3548001
ICD1027 S14.3
UMLS65 C0006091

Summaries for Brachial Plexus Lesion

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MedlinePlus:35 The brachial plexus is a network of nerves that conducts signals from the spine to the shoulder, arm, and hand. brachial plexus injuries are caused by damage to those nerves. symptoms may include a limp or paralyzed arm lack of muscle control in the arm, hand, or wrist lack of feeling or sensation in the arm or hand brachial plexus injuries can occur as a result of shoulder trauma, tumors, or inflammation. sometimes they happen during childbirth when a baby's shoulders become stuck during delivery and the nerves stretch or tear. some brachial plexus injuries may heal without treatment. many children who are injured during birth improve or recover by 3 to 4 months of age. treatment includes physical therapy and, in some cases, surgery. nih: national institute of neurological disorders and stroke

MalaCards based summary: Brachial Plexus Lesion, also known as brachial plexus injuries, is related to non-recovering obstetric brachial plexus lesion and periapical granuloma. An important gene associated with Brachial Plexus Lesion is XIRP1 (Xin Actin Binding Repeat Containing 1), and among its related pathways is Guidance Cues and Growth Cone Motility. Affiliated tissues include skin, spinal cord and breast, and related mouse phenotypes are nervous system and growth/size/body region.

Disease Ontology:10 A brachial plexus neuropathy characterized by an abnormality, usually caused by disease or trauma, located in the brachial plexus.

NINDS:46 The brachial plexus is a network of nerves that conducts signals from the spine to the shoulder, arm, and hand. Brachial plexus injuries are caused by damage to those nerves. Symptoms may include a limp or paralyzed arm; lack of muscle control in the arm, hand, or wrist; and a lack of feeling or sensation in the arm or hand.

Wikipedia:68 The brachial plexus is a network of nerves that conducts signals from the spinal cord, which is housed... more...

Related Diseases for Brachial Plexus Lesion

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Graphical network of the top 20 diseases related to Brachial Plexus Lesion:



Diseases related to brachial plexus lesion

Symptoms for Brachial Plexus Lesion

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Drugs & Therapeutics for Brachial Plexus Lesion

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Drugs for Brachial Plexus Lesion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Heparinapproved, investigational7199005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
2calcium heparin719
3CalamusNutraceutical344

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Aortic Surgery Cerebral Protection Evaluation (ACE) Randomized TrialRecruitingNCT02554032
2An Optic Nerve Sheath Diameter(ONSD) Response to End Tidal Carbon DioxideRecruitingNCT02711774
3Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene BlockWithdrawnNCT01334632

Search NIH Clinical Center for Brachial Plexus Lesion

Genetic Tests for Brachial Plexus Lesion

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Anatomical Context for Brachial Plexus Lesion

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MalaCards organs/tissues related to Brachial Plexus Lesion:

33
Skin, Spinal cord, Breast, Skeletal muscle, Myeloid, Endothelial, B cells

Animal Models for Brachial Plexus Lesion or affiliated genes

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MGI Mouse Phenotypes related to Brachial Plexus Lesion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.0BDNF, CRLF1, GAL, NF1, NLRP3, NRP1
2MP:00053786.9BDNF, GAL, NF1, NLRP3, NRP1, OXT

Publications for Brachial Plexus Lesion

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Articles related to Brachial Plexus Lesion:

(show all 26)
idTitleAuthorsYear
1
Unusual brachial plexus lesion: Hematoma masquerading as a peripheral nerve sheath tumor. (26904368)
2016
2
Long-term outcome of accessory nerve to suprascapular nerve transfer in obstetric brachial plexus lesion: functional, morphological, and electrophysiological results. (26111514)
2015
3
Explaining daily functioning in young adults with obstetric brachial plexus lesion. (25332088)
2014
4
Ultrasound-guided pulse-dose radiofrequency: treatment of neuropathic pain after brachial plexus lesion and arm revascularization. (25525439)
2014
5
The effect of perinatal brachial plexus lesion on upper limb development. (24694070)
2014
6
A cross-sectional study of hand sensation in adults with conservatively treated obstetric brachial plexus lesion. (23121196)
2013
7
Hand sensation in adults with conservatively treated obstetric brachial plexus lesion. (23163967)
2013
8
Recovery of brachial plexus lesions resulting from heavy backpack use: a follow-up case series. (21429232)
2011
9
Development of a set of activities to evaluate the arm and hand function in children with obstetric brachial plexus lesion. (17264110)
2007
10
Extremity shortness in obstetric brachial plexus lesion and its relationship to root avulsion. (18174555)
2007
11
Detection of root avulsion in the dominant C7 obstetric brachial plexus lesion: experience with three-dimensional constructive interference in steady-state magnetic resonance imaging and electrophysiology. (16284563)
2005
12
Brachial plexus lesion following an anterior dislocation of the shoulder. (15167179)
2004
13
Measuring secondary deformities of the shoulder in children with obstetric brachial plexus lesion: reliability of three methods. (12703037)
2003
14
Retroversion of the humeral head in children with an obstetric brachial plexus lesion. (12043783)
2002
15
Rehabilitation of patient with brachial plexus lesion and break in axillary artery. Case study. (8994018)
1996
16
Repair of ruptured spinal nerve roots in a brachial plexus lesion. Case report. (7897534)
1995
17
Brachial plexus lesions and rhabdomyolysis following heroin abuse. Indications for an immunological cause]. (7828462)
1995
18
A new type of brachial plexus lesion to be added to the classical types. (7718039)
1994
19
A fourth type of brachial plexus lesion: the intermediate (C7) palsy. (1791357)
1991
20
Idiopathic brachial plexus lesion with conduction block of the ulnar nerve. (2465129)
1989
21
Prosthetic rehabilitation in unilateral high above-elbow amputation and brachial plexus lesion: case report. (3964062)
1986
22
A spontaneous relocation of a dislocated Neer prosthesis. Occurs with recovery of brachial plexus lesion. (3453468)
1986
23
Brachial plexus lesion complication sternotomy. (7119825)
1982
24
Successful repair of a complete brachial plexus lesion. (5522062)
1970
25
Brachial plexus lesion. (5612894)
1967
26
Axillary aneurysm associated with a brachial plexus lesion. (5911425)
1966

Variations for Brachial Plexus Lesion

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Expression for genes affiliated with Brachial Plexus Lesion

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Search GEO for disease gene expression data for Brachial Plexus Lesion.

Pathways for genes affiliated with Brachial Plexus Lesion

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Pathways related to Brachial Plexus Lesion according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6BDNF, NRP1, SEMA3A

GO Terms for genes affiliated with Brachial Plexus Lesion

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Biological processes related to Brachial Plexus Lesion according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1neural crest cell migration involved in autonomic nervous system developmentGO:190116610.5NRP1, SEMA3A
2trigeminal ganglion developmentGO:006155110.5NRP1, SEMA3A
3dichotomous subdivision of terminal units involved in salivary gland branchingGO:006066610.5NRP1, SEMA3A
4axonal fasciculationGO:000741310.4NRP1, SEMA3A
5sympathetic ganglion developmentGO:006154910.4NRP1, SEMA3A
6branchiomotor neuron axon guidanceGO:002178510.4SEMA3A, SEMA3F
7axon extension involved in axon guidanceGO:004884610.3SEMA3A, SEMA3F
8artery morphogenesisGO:004884410.2NF1, NRP1
9positive regulation of adenylate cyclase activityGO:004576210.2CALCA, NF1
10negative chemotaxisGO:005091910.2SEMA3A, SEMA3F
11negative regulation of osteoclast differentiationGO:004567110.1CALCA, NF1
12sympathetic neuron projection extensionGO:009749010.1NRP1, SEMA3A, SEMA3F
13semaphorin-plexin signaling pathway involved in axon guidanceGO:190228710.1NRP1, SEMA3A, SEMA3F
14semaphorin-plexin signaling pathway involved in neuron projection guidanceGO:190228510.1NRP1, SEMA3A, SEMA3F
15facial nerve structural organizationGO:002161210.1NRP1, SEMA3A, SEMA3F
16sympathetic neuron projection guidanceGO:009749110.1NRP1, SEMA3A, SEMA3F
17negative regulation of axon extension involved in axon guidanceGO:004884310.0NRP1, SEMA3A, SEMA3F
18response to painGO:00482659.9CALCA, TAC1
19response to yeastGO:00018789.9CALCA, TAC1
20antifungal humoral responseGO:00197329.9CALCA, TAC1
21positive regulation of renal sodium excretionGO:00358159.7OXT, TAC1
22neuropeptide signaling pathwayGO:00072189.7CALCA, GAL, TAC1
23cellular response to nerve growth factor stimulusGO:19900909.7CALCA, TAC1
24defense response to Gram-negative bacteriumGO:00508299.6CALCA, TAC1
25regulation of heart rateGO:00020279.5CALCA, OXT, SEMA3A
26negative regulation of blood pressureGO:00457769.3CALCA, OXT
27positive regulation of ossificationGO:00457789.3CALCA, OXT, TAC1
28nerve developmentGO:00216759.2NRP1, SEMA3A, SEMA3F
29axon guidanceGO:00074119.1BDNF, NRP1, SEMA3A, SEMA3F

Sources for Brachial Plexus Lesion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet