MCID: BRC011
MIFTS: 36

Brachial Plexus Neuropathy malady

Categories: Neuronal diseases

Aliases & Classifications for Brachial Plexus Neuropathy

Aliases & Descriptions for Brachial Plexus Neuropathy:

Name: Brachial Plexus Neuropathy 12 29 14
Brachial Plexus Neuropathies 42 69
Brachial Plexopathy 12 52
Brachial Plexus Disorder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3690
ICD10 33 G54.0
MeSH 42 D020516
NCIt 47 C27194
SNOMED-CT 64 3548001
UMLS 69 C0700251

Summaries for Brachial Plexus Neuropathy

MalaCards based summary : Brachial Plexus Neuropathy, also known as brachial plexus neuropathies, is related to radiation induced brachial plexopathy and amyotrophy, hereditary neuralgic, and has symptoms including neuralgia An important gene associated with Brachial Plexus Neuropathy is SEPT9 (Septin 9), and among its related pathways/superpathways is Neural Crest Differentiation. The drugs Acetylcholine and Botulinum Toxins have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, breast and thyroid.

Wikipedia : 71 The brachial plexus is a network of nerves formed by the anterior rami of the lower four cervical nerves... more...

Related Diseases for Brachial Plexus Neuropathy

Diseases related to Brachial Plexus Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
id Related Disease Score Top Affiliating Genes
1 radiation induced brachial plexopathy 12.2
2 amyotrophy, hereditary neuralgic 12.0
3 brachial plexus lesion 11.1
4 neuropathy 10.7
5 plexopathy 10.7
6 breast cancer 10.2
7 thoracic outlet syndrome 10.2
8 hereditary type 2 neuropathy 10.1 MPZ PMP22
9 craniorachischisis 10.1 MPZ PMP22
10 hypertonia 10.1 MPZ PMP22
11 inverted transitional papilloma 10.1 PMP22 SERPINI2
12 charcot-marie-tooth disease, type 2i 10.1 KIF1B MPZ
13 charcot-marie-tooth disease, dominant intermediate d 10.1 KIF1B MPZ
14 female breast nipple and areola cancer 10.1 PMP22 SERPINI2
15 von economo's disease 10.1 MPZ PMP22
16 aortic aneurysm, familial thoracic 4 10.1 KIF1B MPZ
17 pituitary adenoma, prolactin-secreting 10.1 MPZ PMP22
18 methylmalonic aciduria, vitamin b12-responsive, due to defect in synthesis of adenosylcobalamin, cblb complementation type 10.1 KIF1B MPZ
19 mohr-tranebjaerg syndrome 10.1 MPZ PMP22
20 non-gestational choriocarcinoma 10.1 MPZ PMP22
21 choreatic disease 10.0 MPZ PMP22
22 osteomyelitis 10.0
23 status epilepticus 10.0 MPZ PMP22
24 white piedra 10.0 MPZ PMP22
25 venous thoracic outlet syndrome 10.0
26 arterial thoracic outlet syndrome 10.0
27 neurogenic thoracic outlet syndrome 10.0
28 dilated cardiomyopathy 10.0 MPZ PMP22
29 spermatogenic failure, x-linked, 2 10.0 GJB1 MPZ
30 arthritis 9.9
31 septic arthritis 9.9
32 phototoxic dermatitis 9.9 MPZ PMP22
33 chrna1-related congenital myasthenic syndrome 9.9 GJB1 MPZ PMP22
34 surfactant metabolism dysfunction, pulmonary, 2 9.8 GJB1 MPZ PMP22
35 deafness, autosomal recessive 76 9.8 GJB1 MPZ PMP22
36 classic galactosemia and clinical variant galactosemia 9.8 GJB1 MPZ PMP22
37 chkb-related muscle diseases 9.8 GJB1 MPZ PMP22
38 korsakoff's amnesic syndrome 9.8 GJB1 MPZ PMP22
39 senile angioma 9.8 GJB1 MPZ PMP22
40 williams-beuren syndrome 9.8 GJB1 KIF1B MPZ
41 parastremmatic dwarfism 9.8 GJB1 KIF1B MPZ
42 substance-induced psychosis 9.8 GJB1 MPZ PMP22
43 carotid body cancer 9.8 GJB1 MPZ PMP22
44 systemic lupus erythematosus 9.8
45 arteriovenous fistula 9.8
46 burns 9.8
47 leukemia 9.8
48 lymphoma 9.8
49 ehlers-danlos syndrome 9.8
50 scrub typhus 9.8

Graphical network of the top 20 diseases related to Brachial Plexus Neuropathy:



Diseases related to Brachial Plexus Neuropathy

Symptoms & Phenotypes for Brachial Plexus Neuropathy

UMLS symptoms related to Brachial Plexus Neuropathy:


neuralgia

Drugs & Therapeutics for Brachial Plexus Neuropathy

Drugs for Brachial Plexus Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 39)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 4 51-84-3 187
2 Botulinum Toxins Phase 4
3 Cholinergic Agents Phase 4
4 Neurotransmitter Agents Phase 4
5
Ibuprofen Approved Phase 2, Phase 3 15687-27-1 3672
6
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
7
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
8 Analgesics Phase 2, Phase 3
9 Analgesics, Non-Narcotic Phase 2, Phase 3
10 Anti-Inflammatory Agents Phase 2, Phase 3
11 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3
12 Antirheumatic Agents Phase 2, Phase 3
13 Cyclooxygenase Inhibitors Phase 2, Phase 3
14 Peripheral Nervous System Agents Phase 2, Phase 3
15 Antioxidants Phase 3
16 Bone Density Conservation Agents Phase 3
17 Clodronic Acid Phase 3
18 Micronutrients Phase 3
19 Phosphodiesterase Inhibitors Phase 3
20 Platelet Aggregation Inhibitors Phase 3
21 Protective Agents Phase 3
22 Radiation-Protective Agents Phase 3
23 Tocopherols Phase 3
24 Tocotrienols Phase 3
25 Trace Elements Phase 3
26 Vasodilator Agents Phase 3
27 Vitamins Phase 3
28 Tocopherol Nutraceutical Phase 3
29 Tocotrienol Nutraceutical Phase 3
30
Ropivacaine Approved 84057-95-4 71273 175805
31
Morphine Approved, Investigational 57-27-2 5288826
32
Oxycodone Approved, Illicit, Investigational 76-42-6 5284603
33
Oxymorphone Approved, Investigational, Vet_approved 76-41-5 5284604
34 Anesthetics
35 Anesthetics, Local
36 Central Nervous System Depressants
37 Adjuvants, Anesthesia
38 Analgesics, Opioid
39 Narcotics

Interventional clinical trials:

(show all 16)
id Name Status NCT ID Phase
1 Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4
2 Hypoalgesic Effect of Neural Mobilization Versus Ibuprofen Pharmacologic Treatment Completed NCT02593721 Phase 2, Phase 3
3 Trial of Combined Pentoxifylline-tocopherol-clodronate vs Placebo in Radiation-induced Brachial Plexopathy Active, not recruiting NCT01291433 Phase 3
4 Hypoalgesic Effect of Median Nerve Neural Mobilization Compared to a Controlled Group Completed NCT02596815 Phase 2
5 Hypoalgesic Effect of Neural Mobilization Completed NCT02595294 Phase 2
6 Radiation Therapy in Treating Women With Early Stage Breast Cancer Recruiting NCT00909909 Phase 2
7 Thoracic Outlet Syndrome: Case Reports and Analysis With Ultrasound Imaging Completed NCT01196637
8 Longitudinal Experimental Study on ULNTT and Cervico-Thoracic Spine Motion Patterns Relationship Completed NCT02632357
9 GRANVIA®-C Cervical Disc Prosthesis Multicenter European Pilot Study Completed NCT01518582
10 Infraclavicular or Supraclavicular Brachial Plexus Blocks for Elbow Surgery Completed NCT02677506
11 USG Brachial Plexus Block for Upper Extremity Surgery Completed NCT01993290
12 A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation) Completed NCT00580294
13 HBOT Late Radiation Tissue Injury Recruiting NCT02425215
14 Hypofractionated Radiotherapy in Breast Cancer Recruiting NCT03167359
15 Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years Recruiting NCT03121248
16 Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block Withdrawn NCT01334632

Search NIH Clinical Center for Brachial Plexus Neuropathy

Cochrane evidence based reviews: brachial plexus neuropathies

Genetic Tests for Brachial Plexus Neuropathy

Genetic tests related to Brachial Plexus Neuropathy:

id Genetic test Affiliating Genes
1 Brachial Plexus Neuropathy 29

Anatomical Context for Brachial Plexus Neuropathy

MalaCards organs/tissues related to Brachial Plexus Neuropathy:

39
Spinal Cord, Breast, Thyroid, Prostate

Publications for Brachial Plexus Neuropathy

Articles related to Brachial Plexus Neuropathy:

(show top 50) (show all 78)
id Title Authors Year
1
Dosimetric analysis of the brachial plexus among patients with breast cancer treated with post-mastectomy radiotherapy to the ipsilateral supraclavicular area: report of 3 cases of radiation-induced brachial plexus neuropathy. ( 25499205 )
2014
2
Acute brachial plexus neuropathy with involvement of cranial nerves IX, X, XI and XII. ( 23953851 )
2013
3
Brachial plexus neuropathy secondary to postoperative prone positioning for macular hole surgery. ( 25389684 )
2011
4
Electrophysiologic evidence of polyneuropathy in a cat with signs of bilateral brachial plexus neuropathy. ( 19210244 )
2009
5
SEPT9 mutations and a conserved 17q25 sequence in sporadic and hereditary brachial plexus neuropathy. ( 19204161 )
2009
6
Brachial plexus neuropathy resulting from a massively enlarged papillary thyroid carcinoma. ( 19504551 )
2009
7
Radiation-induced brachial plexus neuropathy - aetiopathogenesis, risk factors, differential diagnostics, symptoms and treatment. ( 17357008 )
2007
8
Recurrent lymphoma presenting as brachial plexus neuropathy. ( 17308278 )
2007
9
Friday night palsy: an unusual case of brachial plexus neuropathy. ( 16412841 )
2006
10
Stent grafting resolved brachial plexus neuropathy due to cervical arteriovenous fistula. ( 15583459 )
2004
11
High dose intravenous immune globulin in the treatment of hereditary recurrent brachial plexus neuropathy. ( 12640095 )
2003
12
Acute sporadic brachial plexus neuropathy. ( 23978864 )
2002
13
Inflammation and neuropathic attacks in hereditary brachial plexus neuropathy. ( 12082044 )
2002
14
Contralateral brachial plexus neuropathy after arthroscopic shoulder surgery. ( 12098130 )
2002
15
Arteritis and brachial plexus neuropathy as delayed complications of radiation therapy. ( 11499827 )
2001
16
Recurring brachial plexus neuropathy in a diabetic patient after shoulder surgery and continuous interscalene block. ( 10960400 )
2000
17
Brachial plexus neuropathy. A long-term outcome study. ( 10991813 )
2000
18
Chronic demyelinating hypertrophic brachial plexus neuropathy. ( 10639625 )
2000
19
Brachial plexus neuropathy as unusual onset of diffuse neurolymphomatosis. ( 11214664 )
2000
20
Brachial plexus neuropathy: a rare complication of patient positioning during interventional radiologic procedures. ( 10357484 )
1999
21
Herpetic tracheitis and brachial plexus neuropathy in a child with burns. ( 10501325 )
1999
22
Acquired brachial-plexus neuropathy in the neonate: a rare presentation of late-onset group-B streptococcal osteomyelitis. ( 9698064 )
1998
23
Brachial plexus neuropathy following mantle radiotherapy. ( 9890543 )
1998
24
Chronic relapsing brachial plexus neuropathy with persistent conduction block. ( 9324087 )
1997
25
Brachial plexus neuropathy after botulinum toxin injection. ( 9339718 )
1997
26
Acute brachial plexus neuropathy as a presenting sign of peripheral nervous system involvement in paraproteinaemia. ( 9188910 )
1997
27
Management of radiation-induced brachial plexus neuropathy. Royal College Radiologists. ( 8738825 )
1996
28
Mapping of hereditary neuralgic amyotrophy (familial brachial plexus neuropathy) to distal chromosome 17q. ( 8780104 )
1996
29
Brachial plexus neuropathy after radiotherapy can be treated by specialist surgeons. ( 8605493 )
1996
30
Septic arthritis associated with brachial plexus neuropathy. A case report. ( 8550666 )
1996
31
Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis. ( 8614534 )
1996
32
Brachial plexus neuropathy following attempt at subclavian vein catheterization. Case report. ( 8829409 )
1996
33
Audit of brachial plexus neuropathy following radiotherapy. ( 8845319 )
1995
34
Postoperative brachial plexus neuropathy after total knee replacement under spinal anaesthesia. ( 7577297 )
1995
35
Brachial plexus neuropathy after radiotherapy for breast cancer. ( 8520378 )
1995
36
Hereditary neuropathy with liability to pressure palsies and inherited brachial plexus neuropathy--two genetically distinct disorders. ( 7630211 )
1995
37
Brachial plexus neuropathy secondary to septic arthritis and osteomyelitis: report of two cases. ( 7942033 )
1994
38
Anti-peripheral nerve myelin antibodies and terminal activation products of complement in serum of patients with acute brachial plexus neuropathy. ( 8257306 )
1993
39
Brachial plexus neuropathy associated with scrub typhus: report of a case. ( 1352327 )
1992
40
Anticoagulant-induced shoulder hematoma producing brachial plexus neuropathy--case reports. ( 1321570 )
1992
41
Brachial plexus neuropathy. ( 1848287 )
1991
42
MRI scanning in brachial plexus neuropathy. ( 1667466 )
1991
43
Acute brachial plexus neuropathy secondary to halo-gravity traction in a patient with Ehlers-Danlos syndrome. ( 1851333 )
1991
44
Recurrent brachial plexus neuropathy and giant cell arteritis. ( 2154359 )
1990
45
Radiation-induced brachial plexus neuropathy in breast cancer patients. ( 2261203 )
1990
46
Clinical and electrodiagnostic findings in breast cancer patients with radiation-induced brachial plexus neuropathy. ( 2327236 )
1990
47
Brachial plexus neuropathy. ( 2710149 )
1989
48
Acute ischemic brachial plexus neuropathy following radiation therapy. ( 2927663 )
1989
49
Mononeuritis multiplex with brachial plexus neuropathy coincident with Mycoplasma pneumoniae infection. ( 2540009 )
1989
50
Brachial plexus neuropathy in a gymnast associated with chicken pox. ( 2560941 )
1989

Variations for Brachial Plexus Neuropathy

Expression for Brachial Plexus Neuropathy

Search GEO for disease gene expression data for Brachial Plexus Neuropathy.

Pathways for Brachial Plexus Neuropathy

Pathways related to Brachial Plexus Neuropathy according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.81 GJB1 MPZ PMP22

GO Terms for Brachial Plexus Neuropathy

Cellular components related to Brachial Plexus Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 stress fiber GO:0001725 8.62 SEPT9 XIRP1

Biological processes related to Brachial Plexus Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 myelination GO:0042552 8.62 MPZ PMP22

Sources for Brachial Plexus Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....