MCID: BRN032
MIFTS: 48

Brain Glioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Brain Glioma

MalaCards integrated aliases for Brain Glioma:

Name: Brain Glioma 12 14
Intracranial Glioma 69
Lower Grade Glioma 12
Glioma of Brain 29

Classifications:



External Ids:

Disease Ontology 12 DOID:0060108

Summaries for Brain Glioma

Disease Ontology : 12 A brain cancer that has material basis in glial cells.

MalaCards based summary : Brain Glioma, also known as intracranial glioma, is related to glioma and glioma susceptibility 1. An important gene associated with Brain Glioma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are ERK Signaling and Akt Signaling. The drugs Midazolam and Piracetam have been mentioned in the context of this disorder. Affiliated tissues include brain, t cells and bone, and related phenotypes are cardiovascular system and cellular

Related Diseases for Brain Glioma

Diseases related to Brain Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
id Related Disease Score Top Affiliating Genes
1 glioma 11.3
2 glioma susceptibility 1 10.9
3 pancoast tumor 10.8 GFAP TP53
4 brain stem astrocytic neoplasm 10.8 GFAP TP53
5 brain oligodendroglioma 10.8
6 renal pelvis urothelial papilloma 10.8 GFAP TP53
7 omphalomesenteric cyst 10.8 GFAP MGMT
8 tendon sheath lipoma 10.7 GFAP TP53
9 pediatric infratentorial ependymoma 10.7 EGFR TP53
10 rectum squamous cell carcinoma 10.7 MGMT TP53
11 rh isoimmunization 10.7 GFAP TP53
12 sella turcica neoplasm 10.7 GFAP NES
13 iodine hypothyroidism 10.7 GFAP TP53
14 anaplastic plasmacytoma 10.7 GFAP NES
15 third cranial nerve disease 10.7 GFAP TP53
16 pleural empyema 10.7 GFAP TP53
17 childhood infratentorial neoplasm 10.7 EGFR TP53
18 brainstem intraparenchymal clear cell meningioma 10.7 NES TP53
19 macular retinal edema 10.6 GFAP NES
20 childhood choroid plexus cancer 10.6 GFAP TP53
21 brachial plexus neuritis 10.6 GFAP TP53
22 axonal neuropathy 10.6 GFAP NES
23 subependymal giant cell astrocytoma 10.6 GFAP TP53
24 schwannoma of jugular foramen 10.5 GFAP MGMT TP53
25 prostate adenoid cystic carcinoma 10.5 GFAP MGMT TP53
26 space motion sickness 10.5 GFAP NES
27 aggressive systemic mastocytosis 10.5 GFAP NES TP53
28 brown-vialetto-van laere syndrome 10.5 EGFR MGMT TP53
29 skin hemangioma 10.5 GFAP NES TP53
30 periventricular nodular heterotopia 6 10.5 EGFR GFAP TP53
31 acute porphyria 10.4 EGFR MGMT TP53
32 sudden sensorineural hearing loss 10.4 GFAP NES
33 pineoblastoma 10.4 GFAP TP53
34 duodenum cancer 10.4 FAS TP53
35 juvenile sialidosis type 2 10.4 FAS FASLG
36 gastrointestinal tuberculosis 10.4 FAS FASLG
37 breast fibrosarcoma 10.3 EGFR TP53
38 juvenile astrocytoma 10.3 EGFR GFAP MGMT TP53
39 cystic lymphangioma 10.3 EGFR GFAP MGMT TP53
40 spinal cord glioma 10.2 EGFR GFAP MGMT TP53
41 hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 10.2 EGFR GFAP NES TP53
42 lymphopenia 10.2 EGFR GFAP NES TP53
43 epidermolysa bullosa simplex with muscular dystrophy 10.2 EGFR GFAP MGMT NES
44 macrocephaly, mental retardation, short stature, spastic paraplegia and cns malformations 10.2 FAS FASLG
45 chilaiditi syndrome 10.2 GFAP MAP2
46 hemoglobinemia 10.1 GFAP MAP2
47 atypical lichen myxedematosus 10.1 BMP4 FAS
48 ectopic cushing syndrome 10.0 BMP2 BMP4
49 large intestine lipoma 10.0 GFAP MAP2 TP53
50 toxic pneumonitis 10.0 GFAP MAP2 TP53

Graphical network of the top 20 diseases related to Brain Glioma:



Diseases related to Brain Glioma

Symptoms & Phenotypes for Brain Glioma

MGI Mouse Phenotypes related to Brain Glioma:

44 (show all 14)
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.19 BMP2 BMP4 EGFR FAS FASLG GFAP
2 cellular MP:0005384 10.18 SLIT2 TP53 BMP2 BMP4 EGFR FAS
3 digestive/alimentary MP:0005381 10.15 BMP2 BMP4 EGFR FAS FASLG GFAP
4 mortality/aging MP:0010768 10.14 TP53 BMP2 BMP4 EGFR FAS FASLG
5 endocrine/exocrine gland MP:0005379 10.13 BMP4 EGFR FAS FASLG MAP2 MGMT
6 nervous system MP:0003631 10.02 FASLG GFAP MAP2 ROBO1 SLIT2 TP53
7 craniofacial MP:0005382 9.99 BMP2 BMP4 EGFR FAS ROBO1 TP53
8 integument MP:0010771 9.98 BMP4 EGFR FAS FASLG ROBO1 SLIT2
9 normal MP:0002873 9.86 ROBO1 TP53 BMP2 BMP4 EGFR FAS
10 hearing/vestibular/ear MP:0005377 9.85 BMP2 BMP4 EGFR FAS TP53
11 neoplasm MP:0002006 9.85 EGFR FAS FASLG MGMT ROBO1 TP53
12 renal/urinary system MP:0005367 9.7 BMP4 EGFR FAS FASLG ROBO1 SLIT2
13 reproductive system MP:0005389 9.56 BMP2 BMP4 EGFR FAS FASLG MAP2
14 respiratory system MP:0005388 9.17 BMP4 EGFR FAS FASLG MGMT ROBO1

Drugs & Therapeutics for Brain Glioma

Drugs for Brain Glioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 492)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
2 Piracetam Approved Phase 4,Phase 2 7491-74-9
3
Valproic Acid Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 99-66-1 3121
4
Glutamic Acid Approved, Nutraceutical Phase 4 56-86-0 33032
5 Etiracetam Investigational Phase 4,Phase 1,Phase 2 33996-58-6
6 Anticonvulsants Phase 4,Phase 3,Phase 2,Phase 1
7 Nootropic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
8 Central Nervous System Depressants Phase 4,Phase 3,Phase 1,Phase 2
9 Excitatory Amino Acid Antagonists Phase 4,Phase 2,Phase 1
10 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
11 Anti-Anxiety Agents Phase 4,Phase 2
12 Antimanic Agents Phase 4,Phase 3,Phase 2,Phase 1
13 GABA Agents Phase 4,Phase 3,Phase 2,Phase 1
14 Neuroprotective Agents Phase 4,Phase 2,Phase 1
15 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
16 Protective Agents Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
17 Psychotropic Drugs Phase 4,Phase 3,Phase 2,Phase 1
18 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Phase 1
19
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
20
Etoposide Approved Phase 3,Phase 2,Phase 1 33419-42-0 36462
21
Ifosfamide Approved Phase 3,Phase 1 3778-73-2 3690
22
Levoleucovorin Approved Phase 3,Phase 2,Phase 1 68538-85-2
23
Lomustine Approved Phase 3,Phase 2,Phase 1 13010-47-4 3950
24
Mechlorethamine Approved Phase 3,Phase 2,Phase 1 51-75-2 4033
25
Methotrexate Approved Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
26
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
27
Vincristine Approved, Investigational Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
28
Carmustine Approved Phase 3,Phase 1,Phase 2 154-93-8 2578
29
Procarbazine Approved Phase 3,Phase 2,Phase 1 671-16-9 4915
30
Trioxsalen Approved Phase 3,Phase 2,Phase 1 3902-71-4 5585
31
Carboplatin Approved Phase 3,Phase 2,Phase 1,Early Phase 1 41575-94-4 10339178 498142 38904
32
Tranexamic Acid Approved Phase 3 1197-18-8 5526
33
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
34
Lenograstim Approved Phase 3,Phase 2,Phase 1 135968-09-1
35
Temozolomide Approved, Investigational Phase 3,Phase 2,Phase 1,Early Phase 1 85622-93-1 5394
36 Thiotepa Approved Phase 3,Phase 2,Phase 1 52-24-4 5453
37
Dacarbazine Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 4342-03-4 5351166
38
Aminolevulinic acid Approved Phase 3,Phase 2,Phase 1 106-60-5 137
39
Bevacizumab Approved, Investigational Phase 2, Phase 3, Phase 1, Early Phase 1 216974-75-3
40
Isotretinoin Approved Phase 3,Phase 2,Phase 1 4759-48-2 5538 5282379
41
Dalteparin Approved Phase 3 9005-49-6
42
Heparin Approved, Investigational Phase 3 9005-49-6 772 46507594
43
Vorinostat Approved, Investigational Phase 2, Phase 3,Phase 1 149647-78-9 5311
44
Thioguanine Approved Phase 3,Phase 2 154-42-7 2723601
45
Donepezil Approved Phase 3,Phase 2,Early Phase 1 120014-06-4 3152
46
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
47
Dopamine Approved Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
48
nivolumab Approved Phase 3,Phase 2,Phase 1 946414-94-4
49
Metformin Approved Phase 3,Phase 1 657-24-9 14219 4091
50
chloroquine Approved, Vet_approved Phase 3 54-05-7 2719

Interventional clinical trials:

(show top 50) (show all 917)

id Name Status NCT ID Phase Drugs
1 Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy Unknown status NCT00454935 Phase 4
2 Perampanel in Seizure Patients With Primary Glial Brain Tumors Completed NCT02363933 Phase 4 Perampanel
3 Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy Recruiting NCT02193568 Phase 4
4 Seizure Treatment in Glioma Not yet recruiting NCT03048084 Phase 4 Levetiracetam;Valproic Acid
5 Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas Unknown status NCT00278278 Phase 3 cisplatin;etoposide;ifosfamide;lomustine;methotrexate;prednisone;vincristine sulfate
6 Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas Unknown status NCT00003788 Phase 3 carmustine;lomustine;porfimer sodium;procarbazine hydrochloride
7 Carboplatin Plus Vincristine in Treating Children and Adolescents With Low Grade Glioma Unknown status NCT00003015 Phase 3 carboplatin;vincristine sulfate
8 Cognitive Rehabilitation of Glioma Patients Unknown status NCT00256425 Phase 3
9 SCRT Versus Conventional RT in Children and Young Adults With Low Grade and Benign Brain Tumors Unknown status NCT00517959 Phase 3
10 Efficacy of Tranexamic Acid in Brain Tumor Resections Unknown status NCT01655927 Phase 3 Tranexamic Acid;Placebo: Saline
11 Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors Unknown status NCT00392886 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide;methotrexate;temozolomide;thiotepa;vincristine sulfate
12 Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children Unknown status NCT00749723 Phase 2, Phase 3 carboplatin;etoposide;temozolomide;thiotepa, carboplatin, etoposide;temozolomide, thiotepa;etoposide;trofosfamide/etoposide
13 Radiation Therapy in Treating Patients With Brain Cancer Completed NCT00002620 Phase 3 carmustine;chemotherapy;mitolactol
14 Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children Completed NCT01635140 Phase 3
15 High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas Completed NCT00078988 Phase 3 carboplatin;etoposide;isotretinoin;thiotepa
16 High Light and Low Light Dose PDT in Glioma Completed NCT00118222 Phase 3 porfimer sodium
17 Radiation Therapy or Temozolomide in Treating Patients With Gliomas Completed NCT00182819 Phase 3 temozolomide
18 Standard Radiation Therapy With or Without Stereotactic Radiation Therapy in Treating Patients With Glioma Completed NCT00003916 Phase 3
19 Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid Completed NCT00241670 Phase 3 5-aminolevulinic acid (5-ALA)
20 Dalteparin Low Molecular Weight Heparin for Primary Prophylaxis of Venous Thromboembolism in Brain Tumour Patients Completed NCT00135876 Phase 3 dalteparin
21 Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma Completed NCT00052455 Phase 3 lomustine;procarbazine hydrochloride;temozolomide;vincristine sulfate
22 Standard Radiation Therapy, Higher-Dose Radiation Therapy, or Chemotherapy in Treating Older Patients With Glioblastoma Multiforme Completed NCT00820963 Phase 3 temozolomide
23 Radiotherapy for Malignant Astrocytomas in the Elderly Completed NCT00430911 Phase 3 Radiotherapy
24 Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma Completed NCT00002840 Phase 3 lomustine;procarbazine hydrochloride;vincristine sulfate
25 Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma Completed NCT00002569 Phase 3 lomustine;procarbazine hydrochloride;vincristine sulfate
26 Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma Completed NCT01236560 Phase 2, Phase 3 Temozolomide;Vorinostat
27 Combination Chemotherapy in Treating Children With Progressive Brain Tumors Completed NCT00002944 Phase 3 carboplatin;lomustine;procarbazine hydrochloride;thioguanine;vincristine sulfate
28 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
29 18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety Recruiting NCT03042416 Phase 3 18F-DOPA
30 iMRI Guided Resection in Cerebral Glioma Surgery Recruiting NCT01479686 Phase 3
31 3D Ultra Sound for Resection of Brain Tumors Recruiting NCT02150564 Phase 3
32 Prospective Trial of Two Hypofractionated Radiotherapy Regimens Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children Recruiting NCT01878266 Phase 3
33 Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma Recruiting NCT00887146 Phase 3 concomitant temozolomide (TMZ);procarbazine;adjuvant temozolomide (TMZ);CCNU;vincristine
34 Impact of Surgery on the Treatment of Supratentorial Malignant Gliomas in Subjects Aged 70 and Over Recruiting NCT02892708 Phase 3
35 Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma Recruiting NCT00978458 Phase 3 temozolomide
36 Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma Recruiting NCT01649830 Phase 3 Temozolomide
37 Fluorescence-guided Surgery for Low- and High-grade Gliomas Recruiting NCT01502280 Phase 3 5-Aminolevulinic acid (ALA);Placebo - ascorbic acid
38 VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM Recruiting NCT03149575 Phase 3 VAL-083, Dianhydrogalactitol;Physician's Choice of Salvage Therapy - temozolomide;Physician's Choice of Salvage Therapy - lomustine;Physician's Choice of Salvage Therapy - carboplatin
39 An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) Recruiting NCT02617589 Phase 3 Nivolumab;Temozolomide
40 An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) Recruiting NCT02667587 Phase 3 Nivolumab;Temozolomide
41 Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma Recruiting NCT01507506 Phase 3
42 International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma Recruiting NCT02066220 Phase 2, Phase 3 Reduced-intensity maintenance chemotherapy;Maintenance chemotherapy
43 Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients Recruiting NCT02796261 Phase 3 Eflornithine;Lomustine
44 Phase III Trial of Anaplastic Glioma Without 1p/19q LOH Active, not recruiting NCT00626990 Phase 3 temozolomide
45 Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma Active, not recruiting NCT00003375 Phase 2, Phase 3 lomustine;procarbazine hydrochloride;vincristine sulfate
46 Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas Active, not recruiting NCT00004259 Phase 3 Nitrosourea (BCNU or CCNU);temozolomide
47 Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer Active, not recruiting NCT00045968 Phase 3 Dendritic cell immunotherapy
48 Placebo Controlled Double Blind Crossover Trial of Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma Active, not recruiting NCT02040376 Phase 3 Metformin;Placebo
49 Study of Antineoplaston Therapy + Radiation vs. Radiation Only in Diffuse, Intrinsic, Brainstem Glioma Not yet recruiting NCT02887040 Phase 3 Atengenal;Astugenal
50 Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma Not yet recruiting NCT02864888 Phase 3 Atengenal;Astugenal

Search NIH Clinical Center for Brain Glioma

Genetic Tests for Brain Glioma

Genetic tests related to Brain Glioma:

id Genetic test Affiliating Genes
1 Glioma of Brain 29

Anatomical Context for Brain Glioma

MalaCards organs/tissues related to Brain Glioma:

39
Brain, T Cells, Bone, Bone Marrow, Spinal Cord, Testes, Endothelial

Publications for Brain Glioma

Articles related to Brain Glioma:

(show top 50) (show all 156)
id Title Authors Year
1
The Unwanted Cell Migration in the Brain: Glioma Metastasis. ( 28478595 )
2017
2
C-type natriuretic peptide-modified lipid vesicles: fabrication and use for the treatment of brain glioma. ( 28402948 )
2017
3
Development of a novel imaging agent using peptide-coated gold nanoparticles toward brain glioma stem cell marker CD133. ( 27721007 )
2017
4
Experimental study of a novel tumstatin on C6 brain glioma in vitro. ( 28928823 )
2017
5
Antitumor efficacy of Lf modified daunorubicin plus honokiol liposomes in treatment of brain glioma. ( 28583810 )
2017
6
Anaesthetic management for awake craniotomy in brain glioma resection: initial experience in Military Hospital Mohamed V of Rabat. ( 28904684 )
2017
7
Lactoferrin-coated polysaccharide nanoparticles based on chitosan hydrochloride/hyaluronic acid/PEG for treating brain glioma. ( 27987946 )
2017
8
The long non-coding RNA TP73-AS1 interacted with miR-142 to modulate brain glioma growth through HMGB1/RAGE pathway. ( 28379612 )
2017
9
Lipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cells. ( 28615716 )
2017
10
Ectopic High Expression of E2-EPF Ubiquitin Carrier Protein Indicates a More Unfavorable Prognosis in Brain Glioma. ( 28384045 )
2017
11
Cerebral schistosomiasis: diffusion-weighted imaging helps to differentiate from brain glioma and metastasis. ( 28090792 )
2017
12
IDH1/2 Mutation and MGMT Promoter Methylation - the Relevant Survival Predictors in Czech Patients with Brain Gliomas. ( 27978414 )
2016
13
Upregulation of miR-183 expression and its clinical significance in human brain glioma. ( 27215622 )
2016
14
Targeting vincristine plus tetrandrine liposomes modified with DSPE-PEG2000-transferrin in treatment of brain glioma. ( 27644895 )
2016
15
Asn-Gly-Arg-modified polydopamine-coated nanoparticles for dual-targeting therapy of brain glioma in rats. ( 27655664 )
2016
16
Synergistic Combination of Doxorubicin and Paclitaxel Delivered by Blood Brain Barrier and Glioma Cells Dual Targeting Liposomes for Chemotherapy of Brain Glioma. ( 27033513 )
2016
17
Dual-targeting superparamagnetic iron oxide nanoprobes with high and low target density for brain glioma imaging. ( 26874270 )
2016
18
Malignant transformation of bone marrow stromal cells induced by the brain glioma niche in rats. ( 26590986 )
2016
19
Conjugation Magnetic PAEEP-PLLA Nanoparticles with Lactoferrin as a Specific Targeting MRI Contrast Agent for Detection of Brain Glioma in Rats. ( 27119155 )
2016
20
Circulating tumor cell is a common property of brain glioma and promotes the monitoring system. ( 27517490 )
2016
21
Destruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain glioma. ( 27042063 )
2016
22
Slit2 and Robo1 expression as biomarkers for assessing prognosis in brain glioma patients. ( 27916173 )
2016
23
Multifunctional targeting vinorelbine plus tetrandrine liposomes for treating brain glioma along with eliminating glioma stem cells. ( 27029055 )
2016
24
Molecular and clinical characterization of PD-L1 expression at transcriptional level via 976 samples of brain glioma. ( 27999734 )
2016
25
c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma. ( 27143884 )
2016
26
IVIM perfusion fraction is prognostic for survival in brain glioma. ( 27116215 )
2016
27
GFAP expression is regulated by Pax3 in brain glioma stem cells. ( 27432276 )
2016
28
UPA-sensitive ACPP-conjugated nanoparticles for multi-targeting therapy of brain glioma. ( 25443789 )
2015
29
Brain glioma growth model using reaction-diffusion equation with viscous stress tensor on brain MR images. ( 26518060 )
2015
30
Quantitative assessment of amide proton transfer (APT) and nuclear overhauser enhancement (NOE) imaging with extrapolated semisolid magnetization transfer reference (EMR) signals: II. Comparison of three EMR models and application to human brain glioma at 3 Tesla. ( 26033553 )
2015
31
The expression of p53, mgmt and egfr in brain glioma and clinical significance. ( 25864751 )
2015
32
Comparison of 4'-[methyl-(11)C]thiothymidine ((11)C-4DST) and 3'-deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT) PET/CT in human brain glioma imaging. ( 25853013 )
2015
33
Establishment of C6 brain glioma models through stereotactic technique for laser interstitial thermotherapy research. ( 25883843 )
2015
34
Expression of metastasis-associated protein 3 in human brain glioma related to tumor prognosis. ( 26002011 )
2015
35
3D multimodal MRI brain glioma tumor and edema segmentation: a graph cut distribution matching approach. ( 25467804 )
2015
36
Effects of HMGB1 on proliferation and apoptosis of human brain glioma CD133 cells. ( 26350087 )
2015
37
Noninvasive In Vivo Diagnosis of Brain Glioma Using RGD-Decorated Fluorescent Carbonaceous Nanospheres. ( 26510309 )
2015
38
Diagnostic significance of intraoperative ultrasound contrast in evaluating the resection degree of brain glioma by transmission electron microscopic examination. ( 25591560 )
2015
39
Non-model segmentation of brain glioma tissues with the combination of DWI and fMRI signals. ( 26405892 )
2015
40
Lactoferrin conjugated iron oxide nanoparticles for targeting brain glioma cells in magnetic particle imaging. ( 26412614 )
2015
41
The expression of P2Xa88 receptors in EPCs and their potential role in the targeting of EPCs to brain gliomas. ( 25839324 )
2015
42
Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma. ( 24726749 )
2014
43
Upregulation of the Kank1 gene-induced brain glioma apoptosis and blockade of the cell cycle in G0/G1 phase. ( 24399197 )
2014
44
Differences of SiHa (human cancer of cervix) and BMG-1 (brain glioma) cell lines as 2D and 3D cultures. ( 23881600 )
2014
45
OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma. ( 25128329 )
2014
46
Evaluation of Prognostic Integrin I+2I^1 PET Tracer and Concurrent Targeting Delivery Using Focused Ultrasound for Brain Glioma Detection. ( 25153169 )
2014
47
Terahertz pulsed spectroscopy of paraffin-embedded brain glioma. ( 25003757 )
2014
48
Relationship of 14-3-3zeta (IP), HIF-1I+, and VEGF expression in human brain gliomas. ( 23358800 )
2014
49
Personal history of diabetes, genetic susceptibility to diabetes, and risk of brain glioma: a pooled analysis of observational studies. ( 24220915 )
2014
50
Multifunctional targeting daunorubicin plus quinacrine liposomes, modified by wheat germ agglutinin and tamoxifen, for treating brain glioma and glioma stem cells. ( 25153726 )
2014

Variations for Brain Glioma

Expression for Brain Glioma

Search GEO for disease gene expression data for Brain Glioma.

Pathways for Brain Glioma

Pathways related to Brain Glioma according to GeneCards Suite gene sharing:

(show all 20)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.65 BMP2 BMP4 EGFR FAS FASLG GFAP
2
Show member pathways
13.09 BMP2 BMP4 EGFR FAS FASLG NUDT6
3
Show member pathways
13.02 BMP2 BMP4 EGFR FAS FASLG NUDT6
4
Show member pathways
12.85 BMP2 BMP4 EGFR NUDT6 TP53
5 12.52 EGFR FAS FASLG TP53
6
Show member pathways
12.49 BMP2 BMP4 EGFR NUDT6
7
Show member pathways
12.41 EGFR FAS FASLG TP53
8 12.23 BMP2 BMP4 EGFR FAS FASLG TP53
9 11.98 EGFR FAS FASLG TP53
10 11.84 BMP2 BMP4 FAS
11 11.83 EGFR FAS TP53
12 11.83 FAS MGMT TP53
13 11.72 EGFR MGMT TP53
14 11.64 EGFR GFAP SLIT2 TP53
15 11.47 FAS FASLG TP53
16 11.45 BMP2 BMP4 EGFR NUDT6
17 11.14 FAS FASLG TP53
18 10.96 EGFR FAS FASLG TP53
19 10.92 BMP2 BMP4 GFAP MAP2 NES
20 10.91 BMP2 BMP4

GO Terms for Brain Glioma

Cellular components related to Brain Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.02 BMP2 EGFR FAS FASLG ROBO1

Biological processes related to Brain Glioma according to GeneCards Suite gene sharing:

(show all 27)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.95 BMP4 EGFR FAS MGMT TP53
2 negative regulation of cell migration GO:0030336 9.79 KANK1 ROBO1 SLIT2
3 ossification GO:0001503 9.77 BMP2 BMP4 EGFR
4 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.74 FAS FASLG ROBO1
5 positive regulation of protein phosphorylation GO:0001934 9.73 BMP2 BMP4 EGFR FAS
6 cellular response to growth factor stimulus GO:0071363 9.65 BMP2 BMP4 EGFR
7 regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 9.63 FAS FASLG
8 positive regulation of cartilage development GO:0061036 9.63 BMP2 BMP4
9 positive regulation of ossification GO:0045778 9.62 BMP2 BMP4
10 cell migration involved in sprouting angiogenesis GO:0002042 9.61 ROBO1 SLIT2
11 negative regulation of actin filament polymerization GO:0030837 9.61 KANK1 SLIT2
12 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 9.6 FAS FASLG
13 positive regulation of catenin import into nucleus GO:0035413 9.58 EGFR KANK1
14 renal system process GO:0003014 9.58 BMP4 FAS
15 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.56 BMP4 EGFR
16 multicellular organism development GO:0007275 9.56 BMP2 BMP4 EGFR FAS NES ROBO1
17 Roundabout signaling pathway GO:0035385 9.54 ROBO1 SLIT2
18 telencephalon regionalization GO:0021978 9.52 BMP2 BMP4
19 necroptotic signaling pathway GO:0097527 9.51 FAS FASLG
20 regulation of odontogenesis of dentin-containing tooth GO:0042487 9.49 BMP2 BMP4
21 negative regulation of chemokine-mediated signaling pathway GO:0070100 9.46 ROBO1 SLIT2
22 mesenchymal cell proliferation involved in ureteric bud development GO:0072138 9.4 BMP2 BMP4
23 inflammatory cell apoptotic process GO:0006925 9.37 FAS FASLG
24 positive regulation of pri-miRNA transcription from RNA polymerase II promoter GO:1902895 9.33 BMP2 BMP4 TP53
25 chemorepulsion involved in postnatal olfactory bulb interneuron migration GO:0021836 9.32 ROBO1 SLIT2
26 BMP signaling pathway involved in heart induction GO:0003130 9.26 BMP2 BMP4
27 positive regulation of apoptotic process GO:0043065 9.1 BMP2 BMP4 FAS FASLG SLIT2 TP53

Molecular functions related to Brain Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 co-receptor binding GO:0039706 9.16 BMP2 BMP4
2 identical protein binding GO:0042802 9.1 EGFR FAS GFAP ROBO1 SLIT2 TP53
3 BMP receptor binding GO:0070700 8.96 BMP2 BMP4

Sources for Brain Glioma

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