MCID: BRN071
MIFTS: 52

Brain Injury malady

Categories: Neuronal diseases

Aliases & Classifications for Brain Injury

Aliases & Descriptions for Brain Injury:

Name: Brain Injury 38 51

Classifications:



Summaries for Brain Injury

NINDS : 51 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

MalaCards based summary : Brain Injury is related to personality disorder and niemann-pick disease. An important gene associated with Brain Injury is TMEM158 (Transmembrane Protein 158 (Gene/Pseudogene)), and among its related pathways/superpathways are Tuberculosis and Jak-STAT signaling pathway (KEGG). The drugs Midazolam and Propofol have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and bone, and related phenotypes are Decreased viability with paclitaxel and behavior/neurological

Wikipedia : 71 A brain injury is an injury to the brain of a living organism, and can be categorized by many... more...

Related Diseases for Brain Injury

Diseases related to Brain Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 296)
id Related Disease Score Top Affiliating Genes
1 personality disorder 29.4 APOE BDNF COMT DRD2
2 niemann-pick disease 29.4 GFAP IL6 MBP
3 choroiditis 29.2 IL10 IL1B IL6
4 traumatic brain injury 12.4
5 moderate and severe traumatic brain injury 12.2
6 neonatal hypoxic and ischemic brain injury 12.0
7 bilirubin induced brain injury in the newborn 11.9
8 head injury 11.2
9 pseudobulbar affect 11.0
10 periventricular leukomalacia 11.0
11 agnosia 11.0
12 shaken baby syndrome 10.9
13 cerebral hypoxia 10.9
14 epilepsy 10.9
15 dysphagia 10.9
16 persistent vegetative state 10.9
17 post-traumatic epilepsy 10.9
18 apraxia 10.9
19 swallowing disorders 10.9
20 transient cerebral ischemia 10.9
21 tremor 10.9
22 developmental prosopagnosia 10.7
23 locked-in syndrome 10.7
24 cerebral palsy athetoid 10.6
25 dementia pugilistica 10.6
26 mini stroke 10.6
27 ocular motor apraxia 10.6
28 speech and communication disorders 10.6
29 dyslexia 10.6
30 prosopagnosia 10.6
31 aphasia 10.6
32 cerebritis 10.4
33 vitamin a embryopathy 10.3 EPO IL6
34 repetitive stress injuries 10.3 APOE ENO2
35 myelinoclastic diffuse sclerosis 10.3 ENO2 GFAP S100B
36 piussan lenaerts mathieu syndrome 10.3 ENO2 GFAP S100B
37 pediculus humanus corporis infestation 10.3 ENO2 GFAP S100B
38 hypopituitarism 10.3
39 brain edema 10.3
40 neuronitis 10.3
41 epimetaphyseal dysplasia cataract 10.3 ENO2 GFAP S100B
42 cytomegalovirus disease in patients with impaired cell mediated immunity deemed at risk 10.3 BDNF ENO2 MBP
43 connective tissue cancer 10.3 ENO2 GFAP S100B
44 c-p angle neurinoma 10.3 GFAP MBP S100B
45 flat ductal epithelial atypia 10.2 ENO2 GFAP MBP
46 intracranial arteriosclerosis 10.2 EPO IL6 MBP
47 leydig cell hypoplasia 10.2 EPO IL6 MBP
48 granular cell leiomyosarcoma 10.2 ENO2 EPO GFAP S100B
49 maturity-onset diabetes of the young 10.2 COMT IL10
50 persistent mullerian duct syndrome 10.2 IL10 MBP S100B

Graphical network of the top 20 diseases related to Brain Injury:



Diseases related to Brain Injury

Symptoms & Phenotypes for Brain Injury

GenomeRNAi Phenotypes related to Brain Injury according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with paclitaxel GR00179-A-1 8.92 CASP3 IGF1 IL10
2 Decreased viability with paclitaxel GR00179-A-2 8.92 IGF1

MGI Mouse Phenotypes related to Brain Injury:

44 (show all 19)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.43 APOE ASIC1 BDNF CASP3 COMT DRD2
2 homeostasis/metabolism MP:0005376 10.4 APOE BDNF CASP3 COMT DRD2 EPO
3 cardiovascular system MP:0005385 10.35 GFAP IGF1 IL10 IL1B IL6 SPTAN1
4 cellular MP:0005384 10.35 APOE BDNF CASP3 DRD2 ENO2 EPO
5 nervous system MP:0003631 10.34 APOE ASIC1 BDNF CASP3 COMT DRD2
6 growth/size/body region MP:0005378 10.33 APOE BDNF CASP3 DRD2 ENO2 GFAP
7 mortality/aging MP:0010768 10.29 CASP3 DRD2 EPO GFAP IGF1 IL10
8 hematopoietic system MP:0005397 10.28 IL6 MBP UCHL1 APOE CASP3 COMT
9 immune system MP:0005387 10.25 APOE CASP3 COMT DRD2 EPO GFAP
10 integument MP:0010771 10.24 DRD2 EPO IGF1 IL10 IL1B IL6
11 digestive/alimentary MP:0005381 10.16 IL10 IL6 UCHL1 APOE BDNF CASP3
12 muscle MP:0005369 10.06 APOE CASP3 DRD2 EPO GFAP IGF1
13 normal MP:0002873 10.06 MBP S100B SPTAN1 BDNF DRD2 EPO
14 respiratory system MP:0005388 10 APOE BDNF CASP3 COMT DRD2 ENO2
15 reproductive system MP:0005389 9.97 APOE BDNF CASP3 COMT DRD2 IGF1
16 renal/urinary system MP:0005367 9.91 APOE CASP3 COMT DRD2 IGF1 IL6
17 skeleton MP:0005390 9.81 UCHL1 APOE CASP3 DRD2 EPO IGF1
18 taste/olfaction MP:0005394 9.35 APOE BDNF CASP3 DRD2 ENO2
19 vision/eye MP:0005391 9.23 APOE BDNF CASP3 GFAP IL10 IL6

Drugs & Therapeutics for Brain Injury

Drugs for Brain Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 806)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
2
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 2078-54-8 4943
3
Zinc Approved Phase 4,Phase 3,Phase 2,Phase 1 7440-66-6 32051 23994
4
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 69-65-8 453 6251
5
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2 57-27-2 5288826
6
Citalopram Approved Phase 4,Phase 2,Phase 1 59729-33-8 2771
7
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
8
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
9
Amantadine Approved Phase 4,Phase 2,Phase 3,Phase 1 768-94-5 2130
10
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-61-6, 62-31-7 681
11
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
12
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
13
Remifentanil Approved Phase 4,Phase 2 132875-61-7 60815
14
Sevoflurane Approved, Vet_approved Phase 4,Phase 2,Phase 1 28523-86-6 5206
15
Sufentanil Approved, Investigational Phase 4,Phase 2,Phase 3 56030-54-7 41693
16
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
17
Levodopa Approved Phase 4,Phase 1,Phase 2 59-92-7 6047
18
Acetaminophen Approved Phase 4,Phase 2,Phase 1 103-90-2 1983
19
Ibuprofen Approved Phase 4,Phase 3,Phase 2,Phase 1 15687-27-1 3672
20
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
21
Valproic Acid Approved, Investigational Phase 4,Phase 3,Phase 1 99-66-1 3121
22
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
23
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
24
Memantine Approved, Investigational Phase 4,Phase 2 19982-08-2 4054
25
Etomidate Approved Phase 4,Phase 2 33125-97-2 36339 667484
26
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2 437-38-7 3345
27
Baclofen Approved Phase 4,Phase 3,Phase 2,Phase 1 1134-47-0 2284
28
Acetylcholine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-84-3 187
29
Galantamine Approved Phase 4,Phase 2 357-70-0 9651 908828, 9651
30
Methylphenidate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 113-45-1 4158
31
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
32
Topiramate Approved Phase 4,Phase 2,Phase 1 97240-79-4 5284627
33
Phenytoin Approved, Vet_approved Phase 4,Phase 3,Phase 2 57-41-0 1775
34
Magnesium Sulfate Approved, Vet_approved Phase 4,Phase 3,Phase 2 7487-88-9 24083
35
Sertraline Approved Phase 4,Phase 2,Phase 3 79617-96-2 68617
36
Cosyntropin Approved Phase 4,Phase 2 16960-16-0 16129617
37
Menthol Approved Phase 4,Phase 2,Phase 3,Phase 1 2216-51-5 16666
38
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
39
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 124-94-7 31307
40
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
41
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-02-2 5743
42
Cycloserine Approved Phase 4,Phase 2,Early Phase 1 68-41-7 401 6234
43
Dronabinol Approved, Illicit Phase 4,Phase 3,Phase 1 1972-08-3 16078 2978
44
Glyburide Approved Phase 4,Phase 2,Phase 1 10238-21-8 3488
45
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
46
Rivastigmine Approved, Investigational Phase 4,Phase 3 123441-03-2 77991
47
Norepinephrine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-41-2 439260
48
Methyltestosterone Approved Phase 4,Phase 2 58-18-4 6010
49
Testosterone Approved, Investigational Phase 4,Phase 2 58-22-0 6013
50
Fosphenytoin Approved Phase 4 93390-81-9 56339

Interventional clinical trials:

(show top 50) (show all 2868)
id Name Status NCT ID Phase
1 A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function Unknown status NCT01712477 Phase 4
2 Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Unknown status NCT01207050 Phase 4
3 The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery Unknown status NCT01606111 Phase 4
4 Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury Unknown status NCT02161055 Phase 4
5 A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury Unknown status NCT02071407 Phase 4
6 Antidepressant Maintenance in Traumatic Brain Injury Unknown status NCT00162916 Phase 4
7 Normothermia in Patients With Acute Cerebral Damage Unknown status NCT00491192 Phase 4
8 Growth Hormone and Brain Functioning After Traumatic Brain Injury Unknown status NCT01699308 Phase 4
9 Normoglycemia and Neurological Outcome Unknown status NCT01137773 Phase 4
10 Is Sensory Stimulation Effective in Reducing Time Spent in a Coma or Vegetative State Unknown status NCT00163878 Phase 4
11 Amantadine for Treatment of Symptoms of the Post-Traumatic Confusional State Unknown status NCT00693121 Phase 4
12 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4
13 The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery Unknown status NCT02123355 Phase 4
14 Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? Unknown status NCT01470040 Phase 4
15 Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy Unknown status NCT00505505 Phase 4
16 Dopamine Treatment in Children With Cerebral Palsy With Dystonia- A Double Blind Controlled Study Unknown status NCT01361373 Phase 4
17 Aggressive Fever Control With Intravenous Ibuprofen After Non-traumatic Brain Hemorrhage Unknown status NCT01530880 Phase 4
18 The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia Unknown status NCT01083784 Phase 4
19 TXA in the EMS on the Helicopter and the Ambulance Unknown status NCT02354885 Phase 4
20 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4
21 Creative Therapy to Affect Stroke Outcomes Unknown status NCT01455155 Phase 4
22 Memantine and Constraint-Induced Language Therapy in Chronic Poststroke Aphasia:A Randomized Controlled Trial Unknown status NCT00196703 Phase 4
23 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4
24 A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients Unknown status NCT02147678 Phase 4
25 Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery Unknown status NCT02133638 Phase 4
26 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Unknown status NCT00752934 Phase 4
27 Consequence of Dexmedetomidine on Emergence Deliruim After Sevoflurane Anesthesia in Children With Cerebral Palsy Unknown status NCT02244515 Phase 4
28 Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsy Unknown status NCT01386255 Phase 4
29 The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy Unknown status NCT01256021 Phase 4
30 Efficacy and Safety of Meditoxin® Injection for Cervical Dystonia in Adults With Cerebral Palsy Unknown status NCT01860196 Phase 4
31 Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity Unknown status NCT01786005 Phase 4
32 Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial Craniotomies Unknown status NCT01745081 Phase 4
33 Lactate and Hypoglycemia Unknown status NCT01387477 Phase 4
34 NIMIP: Non Invasive Measurement of the Intracranial Pressure Unknown status NCT01685450 Phase 4
35 Galantamine in the Treatment of Post-Traumatic Headache Unknown status NCT00219869 Phase 4
36 Investigation of Sacroiliac Fusion Treatment (INSITE) Unknown status NCT01681004 Phase 4
37 Anterior Pituitary Hormone Replacement in Traumatic Brain Injury Completed NCT00957671 Phase 4
38 Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery Completed NCT00035139 Phase 4
39 An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits Completed NCT00219245 Phase 4
40 Pharmacological Intervention in Depression After Traumatic Brain Injury Completed NCT00205491 Phase 4
41 The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury Completed NCT01339806 Phase 4
42 The Relationship Between Traumatic Brain Injury and Dopamine (a Chemical in the Brain) Completed NCT02015949 Phase 4
43 Depression and Traumatic Brain Injury Completed NCT00254007 Phase 4
44 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4
45 Optimized Therapy in Severe Traumatic Brain Injured Patients Completed NCT02130674 Phase 4
46 Effect of Erythropoietin on Preterm Brain Injury Completed NCT02036073 Phase 4
47 Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI Completed NCT01750268 Phase 4
48 Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention Completed NCT00618436 Phase 4
49 Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Completed NCT01799941 Phase 4
50 Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity Completed NCT00178646 Phase 4

Search NIH Clinical Center for Brain Injury

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Brain Injury cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Brain Injury:
Hematopoietic stem cells for treatment of ischemic brain injury
Embryonic/Adult Cultured Cells Related to Brain Injury:
Bone marrow-derived hematopoietic stem cells (family)

Genetic Tests for Brain Injury

Anatomical Context for Brain Injury

MalaCards organs/tissues related to Brain Injury:

39
Brain, Eye, Bone, Pituitary, Heart, Testes, Cortex

Publications for Brain Injury

Articles related to Brain Injury:

(show top 50) (show all 1908)
id Title Authors Year
1
Relevance of neuroimaging for neurocognitive and behavioral outcome after pediatric traumatic brain injury. ( 28092022 )
2017
2
COMT Val(158)Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. ( 27769642 )
2017
3
RANTES levels in peripheral blood, CSF and contused brain tissue as a marker for outcome in traumatic brain injury (TBI) patients. ( 28340601 )
2017
4
Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature. ( 27812816 )
2017
5
Predictive validity of disability rating scale in determining functional outcome in patients with severe traumatic brain injury. ( 28084245 )
2017
6
Early neurological deterioration in older adults with traumatic brain injury. ( 28082072 )
2017
7
Childhood Traumatic Brain Injury and the Associations With Risk Behavior in Adolescence and Young Adulthood: A Systematic Review. ( 28092286 )
2017
8
A multi-body dynamics study on a weight-drop test of rat brain injury. ( 28090780 )
2017
9
Inflammation in epileptogenesis after traumatic brain injury. ( 28086980 )
2017
10
Outcome prediction in traumatic brain injury: Is it a "Holy Grail?" ( 28084246 )
2017
11
Long-Term Dosing of Intrathecal Baclofen in the Treatment of Spasticity After Acquired Brain Injury. ( 28082177 )
2017
12
Long term neurobehavioral symptoms and return to productivity in Operation Enduring Freedom/Operation Iraqi Freedom Veterans with and without traumatic brain injury. ( 28088381 )
2017
13
Strategies of successful and unsuccessful simulators coached to feign traumatic brain injury. ( 28084893 )
2017
14
Cerebral amyloid angiopathy: a long-term consequence of traumatic brain injury? ( 27796651 )
2017
15
Antioxidant polymorphisms do not influence the risk of epilepsy or its drug resistance after neonatal hypoxic-ischemic brain injury. ( 28222320 )
2017
16
Reductions in Alexithymia and Emotion Dysregulation After Training Emotional Self-Awareness Following Traumatic Brain Injury: A Phase I Trial. ( 28060205 )
2017
17
Association of traumatic brain injury and Alzheimer disease onset: A systematic review. ( 28506441 )
2017
18
A Coordinated Action of Blood-Borne and Brain Insulin-Like Growth Factor I in the Response to Traumatic Brain Injury. ( 28449086 )
2017
19
Erratum to: Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature. ( 27913939 )
2017
20
Startle suppression after mild traumatic brain injury is associated with an increase in pro-inflammatory cytokines, reactive gliosis and neuronal loss in the caudal pontine reticular nucleus. ( 28089558 )
2017
21
Resting-State Functional Connectivity Alterations Associated with Six-Month Outcomes in Mild Traumatic Brain Injury. ( 28085565 )
2017
22
Protective Effects of Calpain Inhibition on Neurovascular Unit Injury through Downregulating Nuclear Factor-I_B-related Inflammation during Traumatic Brain Injury in Mice. ( 28091411 )
2017
23
Rapid neuroinflammatory response localized to injured neurons after diffuse traumatic brain injury in swine. ( 28081963 )
2017
24
The effect of concussion or mild traumatic brain injury on academic outcomes: A systematic review. ( 28084891 )
2017
25
Characteristics of Moderate and Severe Traumatic Brain Injury of Motorcycle Crashes in Bandung, Indonesia. ( 28087431 )
2017
26
Pediatric Traumatic Brain Injury: Families and Healthcare Team Interaction Trajectories During Acute Hospitalization. ( 28081932 )
2017
27
Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury. ( 28085069 )
2017
28
The SafeBoosC II randomized trial: treatment guided by near-infrared spectroscopy reduces cerebral hypoxia without changing early biomarkers of brain injury. ( 26679155 )
2016
29
Ischemic postconditioning protects against ischemic brain injury by up-regulation of acid-sensing ion channel 2a. ( 27212927 )
2016
30
Does the cause of the mild traumatic brain injury affect the expectation of persistent postconcussion symptoms and psychological trauma? ( 27662262 )
2016
31
Correlation of MRI Brain Injury Findings with Neonatal Clinical Factors in Infants with Congenital Diaphragmatic Hernia. ( 27151752 )
2016
32
Sex-related Differences in Striatal Dopaminergic System after Traumatic Brain Injury. ( 27210290 )
2016
33
Increasing severity of traumatic brain injury in early childhood is associated with a progressive reduction in long-term serum thyroid-stimulating hormone concentrations. ( 26432979 )
2016
34
Traumatic Brain Injury Results in Cellular, Structural and Functional Changes Resembling Motor Neuron Disease. ( 27566977 )
2016
35
Apathy Due to Injury of the Prefrontocaudate Tract Following Mild Traumatic Brain Injury. ( 27661217 )
2016
36
Poster 365 Traumatic Brain Injury Resulting from Pontine and Extrapontine Myelinolysis due to Acute Onset of Pregnancy Induced Diabetes Insipidus: A Case Report. ( 27673118 )
2016
37
Efficiency of an Active Rehabilitation Intervention in a Slow-to-Recover Paediatric Population following Mild Traumatic Brain Injury: A Pilot Study. ( 28078321 )
2016
38
Patient-Specific Thresholds and Doses of Intracranial Hypertension in Severe Traumatic Brain Injury. ( 27165889 )
2016
39
Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP-Sensitive Potassium Channels. ( 27648441 )
2016
40
Long-Term Effects of Ketogenic Diet on Subsequent Seizure-Induced Brain Injury During Early Adulthood: Relationship of Seizure Thresholds to Zinc Transporter-Related Gene Expressions. ( 27147436 )
2016
41
Poster 321 Trazodone Associated Clitoral Priapism in a Transgender Man following Traumatic Brain Injury: A Case Report. ( 27673077 )
2016
42
Potential of the Antibody Against cis-Phosphorylated Tau in the Early Diagnosis, Treatment, and Prevention of Alzheimer Disease and Brain Injury. ( 27654282 )
2016
43
Neuropharmacological and neurochemical evaluation of N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n): a novel serotonergic 5-HT3 receptor antagonist for co-morbid antidepressant- and anxiolytic-like potential using traumatic brain injury model in rats. ( 27662644 )
2016
44
Circulating MicroRNAs as Potential Biomarkers for Traumatic Brain Injury-Induced Hypopituitarism. ( 27027233 )
2016
45
Change of serum levels of thioredoxin in patients with severe traumatic brain injury. ( 26656445 )
2016
46
Valproic Acid Pretreatment Reduces Brain Edema in a Rat Model of Surgical Brain Injury. ( 26463966 )
2016
47
Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline. ( 27203137 )
2016
48
Plasma cytokines IL-6, IL-8, and IL-10 are associated with the development of acute respiratory distress syndrome in patients with severe traumatic brain injury. ( 27630085 )
2016
49
Mindful creativity matters: trajectories of reported functioning after severe traumatic brain injury as a function of mindful creativity in patients' relatives: a multilevel analysis. ( 27663903 )
2016
50
Neuroendocrine Disturbances One to Five or More Years after Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage: Data from the German Database on Hypopituitarism. ( 26914840 )
2016

Variations for Brain Injury

Expression for Brain Injury

Search GEO for disease gene expression data for Brain Injury.

Pathways for Brain Injury

Pathways related to Brain Injury according to GeneCards Suite gene sharing:

(show all 23)
id Super pathways Score Top Affiliating Genes
1 12.13 CASP3 IL10 IL1B IL6
2
Show member pathways
12.11 EPO GFAP IL10 IL6
3 12.01 APOE COMT ENO2 GFAP MBP S100B
4 11.87 BDNF CASP3 IL10 IL1B IL6
5 11.73 ENO2 EPO IGF1 IL6
6 11.69 CASP3 IL10 IL1B IL6
7 11.66 IL10 IL1B IL6
8 11.6 EPO IL10 IL6
9 11.57 IGF1 IL1B IL6
10 11.57 BDNF GFAP IGF1 S100B
11 11.5 CASP3 IL1B IL6
12 11.5 CASP3 IL10 IL1B IL6
13 11.44 CASP3 IL6 UCHL1
14 11.41 IL10 IL1B IL6
15 11.4 IL10 IL1B IL6
16 11.38 EPO IGF1 IL6
17 11.37 EPO IL1B IL6
18 11.21 IL10 IL1B IL6
19 11.2 IL10 IL1B IL6
20 11.18 BDNF CASP3 GFAP IL1B IL6 MBP
21 11.11 IL10 IL1B IL6
22 11.11 APOE IGF1 IL1B IL6
23 10.76 BDNF CASP3

GO Terms for Brain Injury

Cellular components related to Brain Injury according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.81 APOE BDNF EPO IGF1 IL10 IL1B
2 extracellular space GO:0005615 9.56 APOE ENO2 EPO IGF1 IL10 IL1B
3 neuronal cell body GO:0043025 9.02 APOE ENO2 MBP S100B UCHL1

Biological processes related to Brain Injury according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.89 CASP3 EPO IGF1 IL10 IL6
2 response to drug GO:0042493 9.72 CASP3 COMT DRD2 IL10 IL6
3 memory GO:0007613 9.63 ASIC1 S100B SLC24A2
4 negative regulation of neuron death GO:1901215 9.61 APOE EPO IL6
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.58 EPO IGF1 IL6
6 dopamine metabolic process GO:0042417 9.54 COMT DRD2
7 positive regulation of DNA replication GO:0045740 9.54 EPO IGF1 IL6