Aliases & Classifications for Brain Injury

MalaCards integrated aliases for Brain Injury:

Name: Brain Injury 38 51

Classifications:



Summaries for Brain Injury

NINDS : 51 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

MalaCards based summary : Brain Injury is related to endotheliitis and choroiditis. An important gene associated with Brain Injury is ASIC1 (Acid Sensing Ion Channel Subunit 1), and among its related pathways/superpathways are Jak-STAT signaling pathway (KEGG) and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Midazolam and Propofol have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and testes, and related phenotypes are Decreased viability with paclitaxel and behavior/neurological

Wikipedia : 72 A brain injury is an injury to the brain of a living organism, and can be categorized by many... more...

Related Diseases for Brain Injury

Diseases related to Brain Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 332)
id Related Disease Score Top Affiliating Genes
1 endotheliitis 30.7 BDNF ENO2 MBP
2 choroiditis 29.3 ALB IL10 IL6
3 personality disorder 28.9 APOE BDNF COMT DRD2
4 pulmonary embolism 28.8 ALB IL10 IL6
5 traumatic brain injury 12.4
6 moderate and severe traumatic brain injury 12.2
7 neonatal hypoxic and ischemic brain injury 12.0
8 bilirubin induced brain injury in the newborn 11.9
9 head injury 11.2
10 pseudobulbar affect 11.0
11 agnosia 11.0
12 periventricular leukomalacia 11.0
13 locked-in syndrome 11.0
14 shaken baby syndrome 10.9
15 cerebral hypoxia 10.9
16 cerebral atrophy 10.9
17 dysphagia 10.9
18 epilepsy 10.9
19 persistent vegetative state 10.9
20 post-traumatic epilepsy 10.9
21 swallowing disorders 10.9
22 apraxia 10.9
23 transient cerebral ischemia 10.9
24 tremor 10.9
25 west syndrome 10.9
26 postural hypotension 10.9 APOE ENO2
27 virilizing ovarian tumor 10.9 EPO IL6
28 benallegue lacete syndrome 10.8 ENO2 S100B
29 intellectual disability-polydactyly-uncombable hair syndrome 10.8 ENO2 GFAP
30 hydromyelia 10.8 APOE ENO2 S100B
31 meningitis and encephalitis 10.7 ENO2 GFAP S100B
32 nodular medulloblastoma 10.7 ENO2 GFAP
33 pituitary dwarfism with large sella turcica 10.7 ENO2 GFAP S100B
34 pediatric ependymoma 10.7 ENO2 GFAP S100B
35 mixed epithelial stromal tumour 10.7 ENO2 GFAP S100B
36 chilaiditi syndrome 10.7 GFAP MBP
37 developmental prosopagnosia 10.7
38 autosomal dominant compelling helio ophthalmic outburst syndrome 10.7 ENO1 ENO2
39 sternum cancer 10.7 ENO2 GFAP S100B
40 hypoglossal nerve neoplasm 10.7 ENO2 GFAP S100B
41 integrative agnosia 10.7 ENO2 MBP
42 connective tissue cancer 10.7 ENO2 GFAP S100B
43 pancreatoblastoma 10.6 ENO2 GFAP MBP
44 intracranial arteriosclerosis 10.6 EPO IL6 MBP
45 levator syndrome 10.6 EPO IL6 MBP
46 grade iii astrocytoma 10.6 ENO2 GFAP S100B
47 aphasia 10.5
48 microcephaly 10.5
49 cerebral palsy athetoid 10.5
50 dyslexia 10.5

Graphical network of the top 20 diseases related to Brain Injury:



Diseases related to Brain Injury

Symptoms & Phenotypes for Brain Injury

GenomeRNAi Phenotypes related to Brain Injury according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with paclitaxel GR00179-A-1 8.92 CASP3 IGF1 IL10
2 Decreased viability with paclitaxel GR00179-A-2 8.92 IGF1

MGI Mouse Phenotypes related to Brain Injury:

44 (show all 18)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.42 IL10 IL6 MBP S100B SLC24A2 UCHL1
2 homeostasis/metabolism MP:0005376 10.39 ALB APOE BDNF CASP3 COMT DRD2
3 cellular MP:0005384 10.37 BDNF CASP3 DRD2 ENO2 EPO GFAP
4 cardiovascular system MP:0005385 10.31 APOE CASP3 COMT DRD2 EPO GFAP
5 growth/size/body region MP:0005378 10.3 APOE BDNF CASP3 DRD2 ENO2 GFAP
6 nervous system MP:0003631 10.28 ENO2 GFAP IGF1 IL10 IL6 MBP
7 mortality/aging MP:0010768 10.27 APOE BDNF CASP3 DRD2 EPO GFAP
8 digestive/alimentary MP:0005381 10.2 ALB APOE BDNF CASP3 DRD2 GFAP
9 endocrine/exocrine gland MP:0005379 10.19 COMT DRD2 IGF1 IL10 IL6 ALB
10 integument MP:0010771 10.19 S100B UCHL1 APOE BDNF CASP3 DRD2
11 muscle MP:0005369 10.09 ALB APOE CASP3 DRD2 EPO GFAP
12 normal MP:0002873 10.07 ALB BDNF DRD2 EPO GFAP IGF1
13 liver/biliary system MP:0005370 10.02 UCHL1 ALB APOE DRD2 EPO IL10
14 renal/urinary system MP:0005367 9.92 ALB APOE CASP3 COMT DRD2 IGF1
15 reproductive system MP:0005389 9.91 IGF1 IL10 IL6 MBP APOE BDNF
16 respiratory system MP:0005388 9.9 APOE BDNF CASP3 COMT DRD2 ENO2
17 taste/olfaction MP:0005394 9.35 APOE BDNF CASP3 DRD2 ENO2
18 vision/eye MP:0005391 9.23 APOE BDNF CASP3 GFAP IL10 IL6

Drugs & Therapeutics for Brain Injury

Drugs for Brain Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 633)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
2
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 2078-54-8 4943
3
Zinc Approved Phase 4,Phase 2 7440-66-6 32051 23994
4
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 69-65-8 453 6251
5
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2 57-27-2 5288826
6
Citalopram Approved Phase 4,Phase 2,Phase 1 59729-33-8 2771
7
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
8
Amantadine Approved Phase 4,Phase 2,Phase 3,Phase 1 768-94-5 2130
9
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-61-6, 62-31-7 681
10
Ticlopidine Approved Phase 4 55142-85-3 5472
11
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
12
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
13
Remifentanil Approved Phase 4 132875-61-7 60815
14
Sevoflurane Approved, Vet_approved Phase 4,Phase 2,Phase 1 28523-86-6 5206
15
Sufentanil Approved, Investigational Phase 4,Phase 2 56030-54-7 41693
16
Aspirin Approved, Vet_approved Phase 4,Phase 2 50-78-2 2244
17
Levodopa Approved Phase 4,Phase 1,Phase 2 59-92-7 6047
18
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
19
Valproic Acid Approved, Investigational Phase 4,Phase 3,Phase 1 99-66-1 3121
20
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
21
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
22
Memantine Approved, Investigational Phase 4,Phase 2 19982-08-2 4054
23
Etomidate Approved Phase 4 33125-97-2 36339 667484
24
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2 437-38-7 3345
25
Baclofen Approved Phase 4,Phase 3,Phase 2,Phase 1 1134-47-0 2284
26
Acetylcholine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-84-3 187
27
Methylphenidate Approved, Investigational Phase 4,Phase 2,Phase 1 113-45-1 4158
28
Norepinephrine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-41-2 439260
29
Heparin Approved, Investigational Phase 4,Phase 2,Phase 1 9005-49-6 772 46507594
30
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
31
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
32
Magnesium Sulfate Approved, Vet_approved Phase 4,Phase 3,Phase 2 7487-88-9 24083
33
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
34
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-23-7 5754 657311
35 Racepinephrine Approved Phase 4,Phase 3,Phase 2
36
Ibuprofen Approved Phase 4,Phase 3,Phase 2 15687-27-1 3672
37
Rivastigmine Approved, Investigational Phase 4,Phase 3 123441-03-2 77991
38
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
39
Methyltestosterone Approved Phase 4,Phase 2 58-18-4 6010
40
Testosterone Approved, Investigational Phase 4,Phase 2 58-22-0 6013
41
Dalteparin Approved Phase 4,Phase 2 9005-49-6
42
Topiramate Approved Phase 4,Phase 1,Early Phase 1 97240-79-4 5284627
43
Fosphenytoin Approved Phase 4 93390-81-9 56339
44
Phenytoin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 57-41-0 1775
45 Piracetam Approved Phase 4,Phase 3,Phase 2 7491-74-9
46
Dextromethorphan Approved Phase 4,Phase 3 125-71-3 5360696 5362449
47
Guaifenesin Approved, Vet_approved Phase 4,Phase 2 93-14-1 3516
48
Quinidine Approved Phase 4,Phase 2 56-54-2 441074
49
Tizanidine Approved Phase 4,Phase 1 51322-75-9 5487
50
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 57-83-0 5994

Interventional clinical trials:

(show top 50) (show all 2290)

id Name Status NCT ID Phase Drugs
1 A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function Unknown status NCT01712477 Phase 4 Intravenous sedation using propofol;Intravenous sedation with midazolam
2 Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Unknown status NCT01207050 Phase 4 Ramelteon
3 The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery Unknown status NCT01606111 Phase 4 Cerebrolysin;0.9% NaCl, saline
4 Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury Unknown status NCT02161055 Phase 4 Insulin
5 A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury Unknown status NCT02071407 Phase 4 Midazolam;Placebo
6 Antidepressant Maintenance in Traumatic Brain Injury Unknown status NCT00162916 Phase 4 citalopram;Placebo
7 Normothermia in Patients With Acute Cerebral Damage Unknown status NCT00491192 Phase 4 Diclofenac
8 Growth Hormone and Brain Functioning After Traumatic Brain Injury Unknown status NCT01699308 Phase 4 Genotropin (somatropin)
9 Is Sensory Stimulation Effective in Reducing Time Spent in a Coma or Vegetative State Unknown status NCT00163878 Phase 4
10 Amantadine for Treatment of Symptoms of the Post-Traumatic Confusional State Unknown status NCT00693121 Phase 4 Amantadine hydrochloride;Placebo capsule
11 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4 Clopidogrel;Atorvastatin
12 The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery Unknown status NCT02123355 Phase 4 Induction of anesthesia;Sevoflurane, remifentanil ,vecuronium;Dexmedetomidine;Placebo
13 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents Unknown status NCT02404779 Phase 4 cisatracurium besilate
14 Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? Unknown status NCT01470040 Phase 4 discontinuation of aspirin therapy;continuation of aspirin therapy
15 Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy Unknown status NCT00505505 Phase 4 Insulin (Actrapid)
16 Dopamine Treatment in Children With Cerebral Palsy With Dystonia- A Double Blind Controlled Study Unknown status NCT01361373 Phase 4 L- DOPA;placebo
17 The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia Unknown status NCT01083784 Phase 4 Use of prophylactic anticonvulsants (valproate, clonazepam);Control group
18 TXA in the EMS on the Helicopter and the Ambulance Unknown status NCT02354885 Phase 4 Tranexamic Acid
19 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4 Tramadol;Placebo
20 Creative Therapy to Affect Stroke Outcomes Unknown status NCT01455155 Phase 4
21 Memantine and Constraint-Induced Language Therapy in Chronic Poststroke Aphasia:A Randomized Controlled Trial Unknown status NCT00196703 Phase 4 memantine
22 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
23 A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients Unknown status NCT02147678 Phase 4 Etomidate;Propofol;Remifentanil;Anesthesia induction
24 Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery Unknown status NCT02133638 Phase 4 Sevoflurane;Propofol
25 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Unknown status NCT00752934 Phase 4 oral baclofen + placebo;placebo + oral baclofen
26 Effects of Functional Electrical Stimulation on Gait in Children With Cerebral Palsy Unknown status NCT02462018 Phase 4
27 Consequence of Dexmedetomidine on Emergence Deliruim After Sevoflurane Anesthesia in Children With Cerebral Palsy Unknown status NCT02244515 Phase 4 dexmedetomidine
28 The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy Unknown status NCT01256021 Phase 4 Botulinum Toxin Type A
29 Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity Unknown status NCT01786005 Phase 4
30 Anterior Pituitary Hormone Replacement in Traumatic Brain Injury Completed NCT00957671 Phase 4 Human Growth Hormone;Placebo
31 Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery Completed NCT00035139 Phase 4 methylphenidate
32 An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits Completed NCT00219245 Phase 4 Rivastigmine
33 Pharmacological Intervention in Depression After Traumatic Brain Injury Completed NCT00205491 Phase 4 Venlafaxine
34 Intravenous Exenatide in Patients With Acute Brain Injury Completed NCT02058940 Phase 4 Exenatide
35 The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury Completed NCT01339806 Phase 4
36 The Relationship Between Traumatic Brain Injury and Dopamine (a Chemical in the Brain) Completed NCT02015949 Phase 4 Methylphenidate;Placebo
37 Depression and Traumatic Brain Injury Completed NCT00254007 Phase 4 citalopram (celexa)
38 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4 Androgel (Testosterone Gel);Androgel Placebo
39 The Use of Low Molecular Weight Heparin in Traumatic Brain Injury Completed NCT00170378 Phase 4 Enoxaparin
40 Optimized Therapy in Severe Traumatic Brain Injured Patients Completed NCT02130674 Phase 4 Dipeptiven
41 Effect of Erythropoietin on Preterm Brain Injury Completed NCT02036073 Phase 4 recombinant human erythropoietin
42 Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI Completed NCT01750268 Phase 4 Topiramate;Placebo
43 Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention Completed NCT00618436 Phase 4 Levetiracetam;Phenytoin
44 Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Completed NCT01799941 Phase 4 Nuedexta (DM 20 mg/Q 10 mg)
45 Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity Completed NCT00178646 Phase 4 Botox
46 Enteral Glutamine in Neurologically-injured Patients Completed NCT00204971 Phase 4
47 Melatonin to Prevent Brain Injury in Unborn Growth Restricted Babies Completed NCT01695070 Phase 4 Melatonin
48 BOTOX® Versus Zanaflex® for the Treatment of Post-Stroke or Traumatic Brain Injury Upper Limb Spasticity Completed NCT00430196 Phase 4 BOTOX®;Zanaflex®
49 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine Completed NCT00809055 Phase 4 Caffeine citrate
50 Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial Pressure Completed NCT00447018 Phase 4 20% mannitol;7.45% hypertonic saline solution

Search NIH Clinical Center for Brain Injury

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Brain Injury cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Brain Injury:
Hematopoietic stem cells for treatment of ischemic brain injury
Embryonic/Adult Cultured Cells Related to Brain Injury:
Bone marrow-derived hematopoietic stem cells (family)

Genetic Tests for Brain Injury

Anatomical Context for Brain Injury

MalaCards organs/tissues related to Brain Injury:

39
Brain, Spinal Cord, Testes, Bone, Heart, Eye, Cortex

Publications for Brain Injury

Articles related to Brain Injury:

(show top 50) (show all 1977)
id Title Authors Year
1
Critical Care Resource Utilization and Outcomes of Children With Moderate Traumatic Brain Injury. ( 28945629 )
2017
2
Disseminated intravascular coagulation with increased fibrinolysis during the early phase of isolated traumatic brain injury. ( 28826407 )
2017
3
Visual agnosia and focal brain injury. ( 28843416 )
2017
4
The role of necroptosis in status epilepticus-induced brain injury in juvenile rats. ( 28863321 )
2017
5
Hyperbaric oxygen promotes neural stem cell proliferation by activating vascular endothelial growth factor/extracellular signal-regulated kinase signaling after traumatic brain injury. ( 28953090 )
2017
6
Akinetic mutism in a patient with mild traumatic brain injury: A diffusion tensor tractography study. ( 28406325 )
2017
7
The effect of concussion or mild traumatic brain injury on academic outcomes: A systematic review. ( 28084891 )
2017
8
Elevated concentrations of hypoxia-inducible factor-1I+ in patients with fracture and concomitant traumatic brain injury. ( 27687082 )
2017
9
Early neurological deterioration in older adults with traumatic brain injury. ( 28082072 )
2017
10
Intracranial Hypotension Following Traumatic Brain Injury: A Diagnostic and Therapeutic Challenge. ( 28624560 )
2017
11
Resting-State Functional Connectivity Alterations Associated with Six-Month Outcomes in Mild Traumatic Brain Injury. ( 28085565 )
2017
12
Severity of traumatic brain injury correlates with long-term cardiovascular autonomic dysfunction. ( 28770375 )
2017
13
Diagnostic Challenge of Diffusion Tensor Imaging in a Patient With Hemiplegia After Traumatic Brain Injury. ( 28289648 )
2017
14
The research progress of mesenchymal stem cells in the treatment of Traumatic brain injury. ( 28944949 )
2017
15
Traumatic Brain Injury in Adolescents: Incidence and Correlates. ( 28942813 )
2017
16
Do Children Who Sustain Traumatic Brain Injury in Early Childhood Need and Receive Academic Services 7 Years After Injury? ( 28953005 )
2017
17
COMT Val(158)Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. ( 27769642 )
2017
18
Serum insulin-like growth factor-I levels are associated with improved white matter recovery after traumatic brain injury. ( 28574152 )
2017
19
The factor structure of the Disability Rating Scale in individuals with traumatic brain injury. ( 28942681 )
2017
20
Paediatric traumatic brain injury: prognostic insights and outlooks. ( 28938340 )
2017
21
Curcumin mitigates cerebral vasospasm and early brain injury following subarachnoid hemorrhage via inhibiting cerebral inflammation. ( 28948084 )
2017
22
Serum neurofilament light as a biomarker for mild traumatic brain injury in contact sports. ( 28404801 )
2017
23
Pediatric Traumatic Brain Injury: Families and Healthcare Team Interaction Trajectories During Acute Hospitalization. ( 28081932 )
2017
24
A Case of Anoxic Brain Injury Presenting with Agraphia of kanji in the Foreground. ( 28611641 )
2017
25
Validity of Accelerometry to Measure Physical Activity Intensity in Children With an Acquired Brain Injury. ( 28953176 )
2017
26
Risk Factors for Mild Traumatic Brain Injury and Subsequent Post-traumatic Stress Disorder and Mental Health Disorders among US Army Soldiers. ( 28895451 )
2017
27
Clinical characteristics and temporal profile of recovery in patients with favorable outcomes at 6 months after severe traumatic brain injury. ( 28937323 )
2017
28
Not every trauma patient with a radiographic head injury requires transfer for neurosurgical evaluation: Application of the brain injury guidelines to patients transferred to a level 1 trauma center. ( 28939250 )
2017
29
Startle suppression after mild traumatic brain injury is associated with an increase in pro-inflammatory cytokines, reactive gliosis and neuronal loss in the caudal pontine reticular nucleus. ( 28089558 )
2017
30
Tau protein (MAPT) as a possible biochemical marker of traumatic brain injury in postmortem examination. ( 28942078 )
2017
31
Strategies of successful and unsuccessful simulators coached to feign traumatic brain injury. ( 28084893 )
2017
32
Involvement of Nox2 and Nox4 NADPH oxidases in early brain injury after subarachnoid hemorrhage. ( 28330417 )
2017
33
Influence of refractive error on pupillary dynamics in the normal and mild traumatic brain injury (mTBI) populations. ( 28262507 )
2017
34
What is known about sexual health after pediatric acquired brain injury: A scoping review. ( 28946589 )
2017
35
Role of IL-12 in overcoming the low responsiveness of NK cells to missing self after traumatic brain injury. ( 26387630 )
2017
36
Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury. ( 28085069 )
2017
37
Traumatic Brain Injuries during Development: Implications for Alcohol Abuse. ( 28775682 )
2017
38
Transcranial Doppler Ultrasound Use in Pediatric Traumatic Brain Injury. ( 28947894 )
2017
39
Predictive validity of disability rating scale in determining functional outcome in patients with severe traumatic brain injury. ( 28084245 )
2017
40
Decompressive craniectomy in the management of intracranial hypertension after traumatic brain injury: a systematic review and meta-analysis. ( 28821777 )
2017
41
Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature. ( 27812816 )
2017
42
Serum lipocalin-2 concentrations and mortality of severe traumatic brain injury. ( 28943289 )
2017
43
Diffusion tensor imaging tractography and MRI perfusion in post traumatic brain injury hypersomnia. ( 28522105 )
2017
44
West syndrome in three patients with brain injury and a benign course. ( 28794986 )
2017
45
RANTES levels in peripheral blood, CSF and contused brain tissue as a marker for outcome in traumatic brain injury (TBI) patients. ( 28340601 )
2017
46
A multi-body dynamics study on a weight-drop test of rat brain injury. ( 28090780 )
2017
47
Association of traumatic brain injury and Alzheimer disease onset: A systematic review. ( 28506441 )
2017
48
Childhood Traumatic Brain Injury and the Associations With Risk Behavior in Adolescence and Young Adulthood: A Systematic Review. ( 28092286 )
2017
49
Epidemiology, Management, and Functional Outcomes of Traumatic Brain Injury in sub-Saharan Africa. ( 28943422 )
2017
50
Cocaine Abuse, Traumatic Brain Injury, and Preexisting Brain Lesions as Risk Factors for Bupropion-Associated Psychosis. ( 28590371 )
2017

Variations for Brain Injury

Expression for Brain Injury

Search GEO for disease gene expression data for Brain Injury.

Pathways for Brain Injury

GO Terms for Brain Injury

Cellular components related to Brain Injury according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.97 ALB APOE BDNF EPO IGF1 IL10
2 myelin sheath GO:0043209 9.33 ALB MBP UCHL1
3 extracellular space GO:0005615 9.28 ALB APOE ENO1 ENO2 EPO IGF1
4 cell body GO:0044297 9.26 COMT EPO
5 phosphopyruvate hydratase complex GO:0000015 8.96 ENO1 ENO2

Biological processes related to Brain Injury according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.81 ALB APOE IGF1 IL6
2 response to drug GO:0042493 9.77 CASP3 COMT DRD2 IL10 IL6
3 negative regulation of apoptotic process GO:0043066 9.73 ALB CASP3 EPO IGF1 IL10 IL6
4 memory GO:0007613 9.67 ASIC1 S100B SLC24A2
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.65 EPO IGF1 IL6
6 negative regulation of neuron death GO:1901215 9.61 APOE EPO IL6
7 positive regulation of protein import into nucleus, translocation GO:0033160 9.55 IGF1 IL6
8 response to wounding GO:0009611 9.54 CASP3 IL6
9 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.52 IL10 MBP
10 positive regulation of DNA replication GO:0045740 9.5 EPO IGF1 IL6
11 long-term synaptic potentiation GO:0060291 9.4 S100B SLC24A2
12 response to lipopolysaccharide GO:0032496 9.35 CASP3 COMT EPO IL10 IL6
13 neuron projection regeneration GO:0031102 9.16 APOE
14 response to inactivity GO:0014854 9.16 DRD2 IL10
15 response to glucocorticoid GO:0051384 8.92 CASP3 IL10 IL6 S100B

Molecular functions related to Brain Injury according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 BDNF IGF1 IL10 IL6
2 tau protein binding GO:0048156 9.16 APOE S100B
3 phosphopyruvate hydratase activity GO:0004634 8.62 ENO1 ENO2
4 protein binding GO:0005515 10.19 ALB APOE ASIC1 CASP3 COMT DRD2

Sources for Brain Injury

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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