MCID: BRN080
MIFTS: 41

Brain Ischemia malady

Categories: Neuronal diseases

Aliases & Classifications for Brain Ischemia

Aliases & Descriptions for Brain Ischemia:

Name: Brain Ischemia 38 52 69

Classifications:



Summaries for Brain Ischemia

MalaCards based summary : Brain Ischemia is related to ischemia and neuronitis. An important gene associated with Brain Ischemia is KCNB1 (Potassium Voltage-Gated Channel Subfamily B Member 1), and among its related pathways/superpathways are Melatonin metabolism and effects and Photodynamic therapy-induced HIF-1 survival signaling. The drugs Dopamine and Levodopa have been mentioned in the context of this disorder. Affiliated tissues include Brain and Brain.

Wikipedia : 71 Brain ischemia (a.k.a. cerebral ischemia, cerebrovascular ischemia) is a condition in which there is... more...

Related Diseases for Brain Ischemia

Diseases related to Brain Ischemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
id Related Disease Score Top Affiliating Genes
1 ischemia 10.9
2 neuronitis 10.4
3 hypothalamic neoplasm 10.2 GFAP NES
4 angiofollicular lymph hyperplasia 10.2 GFAP NES
5 childhood kidney cell carcinoma 10.2 GFAP NES
6 nephrogenic adenoma of urinary bladder 10.2 GFAP NES
7 paternal uniparental disomy of chromosome 1 10.2 GFAP NES
8 adult brainstem gliosarcoma 10.2 GFAP NES
9 male reproductive system disease 10.2 GFAP NES
10 childhood embryonal testis carcinoma 10.2 GFAP NES
11 superior vena cava syndrome 10.2 GFAP NES
12 osteopetrosis, autosomal recessive 8 10.2 GFAP NES
13 cerebritis 10.2
14 auricular cancer 10.2 GFAP NES
15 dysgerminoma of ovary 10.2 GFAP NES
16 pediculus humanus corporis infestation 10.2 GFAP NES
17 children's interstitial lung disease 10.2 GFAP MAP2
18 fallopian tube benign neoplasm 10.2 GFAP NES
19 hemorrhagic proctocolitis 10.2 GFAP MAP2
20 brain stem astrocytic neoplasm 10.1 GFAP MAP2
21 clear cell variant infiltrating bladder urothelial carcinoma 10.1 GFAP MAP2
22 poikiloderma with neutropenia 10.0 EDN1 NOS2
23 granulomatous myositis 10.0 MAP2 NES
24 vulvar benign neoplasm 10.0 GFAP MAP2 NES
25 adenofibroma 10.0 GFAP MAP2 NES
26 calcific tendinitis 10.0 GFAP MAP2 NES
27 breast squamous cell carcinoma 10.0 GFAP MAP2
28 inner ear cancer 10.0 GFAP MAP2 NES
29 central nervous system hemangioma 10.0 GFAP MAP2 NES
30 zellweger syndrome 10.0 EDN1 NOS2
31 persistent vegetative state 10.0 MAP2 NES
32 hypoxia 10.0
33 leydig cell hypoplasia 9.9 NES NOS2
34 brain injury 9.9
35 cerebral artery occlusion 9.8
36 cardiac arrest 9.8
37 hyperglycemia 9.7
38 endotheliitis 9.7
39 angioedema 9.6
40 traumatic brain injury 9.6
41 vascular dementia 9.6
42 protein-energy malnutrition 9.6
43 carotid stenosis 9.6
44 dementia 9.6
45 aneurysm 9.5
46 epilepsy 9.5
47 anoxia 9.5
48 encephalopathy 9.5
49 carotid artery disease 9.5
50 schizophrenia 9.5

Graphical network of the top 20 diseases related to Brain Ischemia:



Diseases related to Brain Ischemia

Symptoms & Phenotypes for Brain Ischemia

Drugs & Therapeutics for Brain Ischemia

Drugs for Brain Ischemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 707)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 2,Phase 3,Early Phase 1 51-61-6, 62-31-7 681
2
Levodopa Approved Phase 4,Phase 3 59-92-7 6047
3
Ephedrine Approved Phase 4,Phase 3,Phase 2 299-42-3 9294
4
Oxymetazoline Approved Phase 4,Phase 3,Phase 2 1491-59-4 4636
5
Phenylephrine Approved Phase 4,Phase 3,Phase 2 59-42-7 6041
6
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2 90-82-4 7028
7
Atenolol Approved Phase 4 29122-68-7 2249
8
Valsartan Approved, Investigational Phase 4,Phase 2 137862-53-4 60846
9
Benzocaine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
10
Nimodipine Approved Phase 4,Phase 2 66085-59-4 4497
11
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
12 Nadroparin Approved Phase 4 9041-08-1
13
Zinc Approved Phase 4,Phase 2,Phase 3,Phase 1 7440-66-6 32051 23994
14
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
15
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 55142-85-3 5472
16
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1 2216-51-5 16666
17
Nicardipine Approved Phase 4,Phase 3 55985-32-5 4474
18
Dorzolamide Approved Phase 4 120279-96-1 3154 5284549
19
Timolol Approved Phase 4,Phase 1 26839-75-8 33624 5478
20
Tirofiban Approved Phase 4 144494-65-5 60947
21
Candesartan Approved Phase 4,Phase 3 139481-59-7 2541
22
Magnesium Sulfate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 7487-88-9 24083
23
Cilostazol Approved Phase 4,Phase 3 73963-72-1 2754
24
Antipyrine Approved Phase 4,Phase 3,Phase 2,Phase 1 60-80-0 2206
25
Dalteparin Approved Phase 4,Phase 2 9041-08-1
26
Argatroban Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 74863-84-6 152951
27
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 2078-54-8 4943
28
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2 437-38-7 3345
29
Warfarin Approved Phase 4,Phase 2,Phase 3,Phase 1 81-81-2 6691 54678486
30
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 2 111025-46-8 4829
31
Allopurinol Approved Phase 4,Phase 3 315-30-0 2094
32
Acenocoumarol Approved Phase 4 152-72-7 9052 54676537
33
Rivaroxaban Approved Phase 4,Phase 2,Phase 3 366789-02-8
34
Apixaban Approved Phase 4,Phase 3,Phase 2 503612-47-3 10182969
35 Edoxaban Approved Phase 4,Phase 2,Phase 3 480449-70-5
36
Sevoflurane Approved, Vet_approved Phase 4,Phase 2 28523-86-6 5206
37
Glyburide Approved Phase 4,Phase 3,Phase 2,Phase 1 10238-21-8 3488
38 Piracetam Approved Phase 4,Phase 2 7491-74-9
39
Tenecteplase Approved Phase 4,Phase 3,Phase 2 191588-94-0
40
Dipyridamole Approved Phase 4,Phase 3,Phase 2 58-32-2 3108
41
Histamine Approved, Investigational Phase 4,Phase 2 75614-87-8, 51-45-6 774
42
Amlodipine Approved Phase 4,Phase 2 88150-42-9 2162
43
Losartan Approved Phase 4,Phase 3 114798-26-4 3961
44
Triflusal Approved Phase 4 322-79-2
45
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3 51-43-4 5816
46
Probucol Approved Phase 4 23288-49-5 4912
47
Desflurane Approved Phase 4 57041-67-5 42113
48
Isoflurane Approved, Vet_approved Phase 4,Phase 2,Phase 3 26675-46-7 3763
49
Remifentanil Approved Phase 4,Phase 3 132875-61-7 60815
50
Thiopental Approved, Vet_approved Phase 4 76-75-5 3000715

Interventional clinical trials:

(show top 50) (show all 2049)
id Name Status NCT ID Phase
1 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4
2 Dopamine Treatment in Children With Cerebral Palsy With Dystonia- A Double Blind Controlled Study Unknown status NCT01361373 Phase 4
3 Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid Surgery Unknown status NCT01794273 Phase 4
4 Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol Unknown status NCT02403349 Phase 4
5 Nimodipine for Treating Acute Massive Cerebral Infarction Unknown status NCT02248233 Phase 4
6 Safety and Efficacy of Heparin and Nadroparin in the Acute Phase of Ischemic Stroke Unknown status NCT01862978 Phase 4
7 Valsartan Efficacy on Modest Blood Pressure Reduction in Acute Ischemic Stroke Unknown status NCT00874601 Phase 4
8 Efficacy Study of Huatuo Zaizao Pills in Improving of Neural Function in Acute Ischemic Stroke Unknown status NCT01758536 Phase 4
9 Comparison of Two Strategies for Glycemic Control in Acute Ischemic Stroke Unknown status NCT00747279 Phase 4
10 The Effect of Erigeron Injection on Acute Cerebral Infarction Serum VEGF, MMP-9 and EPC Levels Unknown status NCT01926834 Phase 4
11 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4
12 The Dynamic Effect of Non-cytochrome P450 Isoenzyme 3A4(CYP3A4)-Metabolized and Cytochrome P450 Isoenzyme 3A4(CYP3A4)-Metabolized Statins on Clopidogrel Resistance in Patients With Cerebral Infarction Unknown status NCT02411903 Phase 4
13 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
14 Efficacy and Safety Study of Nimodipine to Prevent Mild Cognitive Impairment After Acute Ischemic Strokes Unknown status NCT01220622 Phase 4
15 The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage Unknown status NCT01346748 Phase 4
16 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4
17 A Clinical Trial of Danhong Injection in Treating Acute Ischemic Stroke Unknown status NCT02152280 Phase 4
18 Multi-"Omics" Research of Danhong Injection to Treat Acute Ischemic Stroke Unknown status NCT02176395 Phase 4
19 Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty Unknown status NCT00262574 Phase 4
20 IV Double and Triple Concentrated Nicardipine for Stroke and ICH Unknown status NCT00325793 Phase 4
21 Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma Patients Unknown status NCT02053298 Phase 4
22 Safety Study of Melatonin in Stroke Patients Unknown status NCT01863277 Phase 4
23 Japanese Primary Prevention Project With Aspirin Unknown status NCT00225849 Phase 4
24 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
25 Efficacy and Safety of Different Dose of Tirofiban in Interventional Treatment of Complex Coronary Artery Disease Unknown status NCT02294994 Phase 4
26 LDL-C Lowering Efficacy and Safety of Rosuvastatin 20 mg/Day to10 mg/Day in Chinese ACS(Acute Coronary Syndrome) Patients Unknown status NCT02077257 Phase 4
27 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
28 Effects of Intensive Statin Treatment on Left Ventricular Function Unknown status NCT01936103 Phase 4
29 Acute Candesartan Cilexetil Outcomes Stroke Trial (ACCOST) Unknown status NCT00108706 Phase 4
30 Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism Unknown status NCT02316743 Phase 4
31 Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit Unknown status NCT00862160 Phase 4
32 Single High Dose Vitamin C, E in Severe Birth Asphyxia Completed NCT01743742 Phase 4
33 ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial Completed NCT00161070 Phase 4
34 Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm Birth Completed NCT00120588 Phase 4
35 Post-marketing Clinical Study of Alteplase for Acute Ischemic Stroke (Japan Alteplase Clinical Trial Ⅱ:J-ACT Ⅱ) Completed NCT00412867 Phase 4
36 The Effect of Cilostazol Compared to Aspirin on Endothelial Function in Acute Cerebral Ischemia Patients Completed NCT03116269 Phase 4
37 The Effect of Ventilation on Cerebral Oxygenation in the Sitting Position Completed NCT01546636 Phase 4
38 Myocardial Damage In Patients With Cerebral Infarction Completed NCT00306579 Phase 4
39 Cilostazol in Acute Ischemic Stroke Treatment (CAIST) Completed NCT00272454 Phase 4
40 AISTCM-Outcome Measurement of Acute Ischemic Stroke With Traditional Chinese Medicine Completed NCT00351806 Phase 4
41 Merci Registry - Real World Use of the Merci Retrieval System in Acute Ischemic Stroke Completed NCT00478478 Phase 4
42 Edaravone-Sodium Ozagrel Comparative Post-Marketing Study on Acute Ischemic Stroke Completed NCT00200356 Phase 4
43 The Effect of Losartan Versus Amlodipine-based Therapy in Ischemic Stroke (0954-338)(COMPLETED) Completed NCT00754429 Phase 4
44 Atorvastatin in Acute Stroke Treatment Completed NCT02225834 Phase 4
45 Safety and Efficacy of Clopidogrel for Cerebral Infarction Treatment Completed NCT00386191 Phase 4
46 Comparison of Triflusal and Clopidogrel in Secondary Prevention of Stroke Based on the Genotyping Completed NCT01174693 Phase 4
47 Overcome Biochemical Aspirin Resistance Through Cilostazol Combination Completed NCT00446641 Phase 4
48 The Study on Profile and Genetic Factors of Aspirin Resistance (ProGEAR Study) Completed NCT00250380 Phase 4
49 Thrombectomy REvascularization of Large Vessel Occlusions in Acute Ischemic Stroke (TREVO) Completed NCT01088672 Phase 4
50 Post-marketing Study of Cilostazol (Cilostazol Stroke Prevention Study 2) Completed NCT00234065 Phase 4

Search NIH Clinical Center for Brain Ischemia

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Brain Ischemia cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Brain Ischemia:
Mesenchymal stem cell-derived neuronal progenitor cells for the treatment of ischemic brain damage
Embryonic/Adult Cultured Cells Related to Brain Ischemia:
Neural progenitor cells PMIDs: 21300404

Genetic Tests for Brain Ischemia

Anatomical Context for Brain Ischemia

MalaCards organs/tissues related to Brain Ischemia:

39
Brain, Cortex, Monocytes, Endothelial, Bone, Neutrophil, Bone Marrow
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Brain Ischemia:
id Tissue Anatomical CompartmentCell Relevance
1 Brain Forebrain White Matter Fibrous Astrocyte Cells Potential therapeutic candidate
2 Brain Neocortex Protoplasmic Astrocyte Cells Potential therapeutic candidate

Publications for Brain Ischemia

Articles related to Brain Ischemia:

(show top 50) (show all 619)
id Title Authors Year
1
Curcumin reverses neurochemical, histological and immuno-histochemical alterations in the model of global brain ischemia. ( 28053883 )
2017
2
Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry. ( 27888142 )
2017
3
Glutamate dehydrogenase as a neuroprotective target against brain ischemia and reperfusion. ( 27845178 )
2017
4
Polarizing the immune system towards neuroprotection in brain ischemia. ( 26981089 )
2016
5
OS 18-02 ANTIHYPERTENSIVE TREATMENT AND RISK OF BRAIN ISCHEMIA DUE TO CAROTID STENOSIS IN A SURVEY OF HOSPITALISED PATIENTS AGED 90 YEARS AND OLDER. ( 27642991 )
2016
6
Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice. ( 27538712 )
2016
7
Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway. ( 27596278 )
2016
8
Stress-responsive heme oxygenase-1 isoenzyme participates in Toll-like receptor 4-induced inflammation during brain ischemia. ( 26966782 )
2016
9
Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia. ( 27889412 )
2016
10
Molecular Biological Roles of Oxidative Stress in Acute Brain Ischemia. ( 27181902 )
2016
11
The antioxidative property of melatonin against brain ischemia. ( 27108742 )
2016
12
SUMO-specific protease 1 protects neurons from apoptotic death during transient brain ischemia/reperfusion. ( 27882949 )
2016
13
Neuroprotective effect of resveratrol against brain ischemia reperfusion injury in rats entails reduction of DJ-1 protein expression and activation of PI3K/Akt/GSK3b survival pathway. ( 27109835 )
2016
14
Alzheimer-associated presenilin 2 gene is dysregulated in rat medial temporal lobe cortex after complete brain ischemia due to cardiac arrest. ( 26721367 )
2016
15
OS 18-02 ANTIHYPERTENSIVE TREATMENT AND RISK OF BRAIN ISCHEMIA DUE TO CAROTID STENOSIS IN A SURVEY OF HOSPITALISED PATIENTS AGED 90 YEARS AND OLDER. ( 27754070 )
2016
16
History of the Letzte Wiese/Last Meadow Concept of Brain Ischemia. ( 26757752 )
2016
17
Concurrent Glycogen and Lactate Imaging with FTIR Spectroscopy To Spatially Localize Metabolic Parameters of the Glial Response Following Brain Ischemia. ( 27690391 )
2016
18
Stress Granule Induction after Brain Ischemia Is Independent of Eukaryotic Translation Initiation Factor (eIF) 2I+ Phosphorylation and Is Correlated with a Decrease in eIF4B and eIF4E Proteins. ( 27836976 )
2016
19
A Novel GSK-3I^ inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway. ( 27108601 )
2016
20
Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) improves brain ischemia-induced pulmonary injury in rats associated to TNF-I+ expression. ( 26931747 )
2016
21
N-Acetylcysteine and Ceftriaxone as Preconditioning Strategies in Focal Brain Ischemia: Influence on Glutamate Transporters Expression. ( 26861954 )
2016
22
The Role of I_ Opioid Receptor in Brain Ischemia. ( 27495821 )
2016
23
Estrogen replacement therapy-induced neuroprotection against brain ischemia-reperfusion injury involves the activation of astrocytes via estrogen receptor I^. ( 26891996 )
2016
24
Clinical Efficacy and Meta-Analysis of Stem Cell Therapies for Patients with Brain Ischemia. ( 27656217 )
2016
25
Lectin Complement Pathway and Its Bloody Interactions in Brain Ischemia. ( 27811336 )
2016
26
Butylphthalide Suppresses Neuronal Cells Apoptosis and Inhibits JNK-Caspase3 Signaling Pathway After Brain Ischemia /Reperfusion in Rats. ( 27015680 )
2016
27
Discrepancy in Expression of I^-Secretase and Amyloid-I^ Protein Precursor in Alzheimer-Related Genes in the Rat Medial Temporal Lobe Cortex Following Transient Global Brain Ischemia. ( 26890784 )
2016
28
PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia. ( 27423516 )
2016
29
The neuroprotective effects of preconditioning exercise on brain damage and neurotrophic factors after focal brain ischemia in rats. ( 26808606 )
2016
30
Apoptosis and Acute Brain Ischemia in Ischemic Stroke. ( 27823556 )
2016
31
Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice. ( 27488634 )
2016
32
Induction of Perivascular Neural Stem Cells and Possible Contribution to Neurogenesis Following Transient Brain Ischemia/Reperfusion Injury. ( 27352866 )
2016
33
Brain ischemia with Alzheimer phenotype dysregulates Alzheimer's disease-related proteins. ( 26940197 )
2016
34
Hyperbaric oxygen increases tissue-plasminogen activator-induced thrombolysis in vitro, and reduces ischemic brain damage and edema in rats subjected to thromboembolic brain ischemia. ( 27867469 )
2016
35
The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity. ( 27813297 )
2016
36
Hyperbaric oxygen modalities are differentially effective in distinct brain ischemia models. ( 27826422 )
2016
37
Early Glycogen Synthase Kinase-3I^ (GSK-3I^) and Protein Phosphatase 2A (PP2A) independent tau dephosphorylation during global brain ischemia and reperfusion following cardiac arrest and the role of the Adenosine Monophosphate Kinase (AMPK) pathway. ( 27177932 )
2016
38
Downregulation of GABAA Receptor Recycling Mediated by HAP1 Contributes to Neuronal Death in In Vitro Brain Ischemia. ( 26732589 )
2016
39
Unfolded protein response in brain ischemia: A timely update. ( 27733676 )
2016
40
Endoplasmic reticulum stress in brain ischemia. ( 26289799 )
2015
41
The Differences in the Cellular and Plasma Antioxidative Capacity Between Transient and Defined Focal Brain Ischemia: Does it Suggest Supporting Time-Dependent Neuroprotection Therapy? ( 26335597 )
2015
42
Delayed hyperoxic ventilation attenuates oxygen-induced free radical accumulation during early reperfusion after global brain ischemia. ( 25569795 )
2015
43
Phosphoinositide 3-Kinase I^ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia. ( 26452362 )
2015
44
Role of morphine preconditioning and nitric oxide following brain ischemia reperfusion injury in mice. ( 25810871 )
2015
45
Intravenous treatment with coenzyme Q10 improves neurological outcome and reduces infarct volume after transient focal brain ischemia in rats. ( 26371950 )
2015
46
Phosphodiesterase Inhibition as a Therapeutic Target for Brain Ischemia. ( 26350339 )
2015
47
Brain ischemia, endoplasmic reticulum stress, and astroglial activation: new insights. ( 25586383 )
2015
48
Advanced neuroprotection for brain ischemia: an alternative approach to minimize stroke damage. ( 26138255 )
2015
49
The Effects of Xanthine Oxidoreductase Inhibitors on Oxidative Stress Markers following Global Brain Ischemia Reperfusion Injury in C57BL/6 Mice. ( 26230326 )
2015
50
Evaluation of neuronal protective effects of xanthine oxidoreductase inhibitors on severe whole-brain ischemia in mouse model and analysis of xanthine oxidoreductase activity in the mouse brain. ( 25744353 )
2015

Variations for Brain Ischemia

Expression for Brain Ischemia

Search GEO for disease gene expression data for Brain Ischemia.

Pathways for Brain Ischemia

Pathways related to Brain Ischemia according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.82 EDN1 MAP2
2 10.72 EDN1 NOS2
3 10.7 GFAP MAP2 NES
4 10.49 ADCY10 EDN1

GO Terms for Brain Ischemia

Cellular components related to Brain Ischemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 9.16 GFAP NES
2 basal part of cell GO:0045178 8.96 ADCY10 EDN1
3 dendrite GO:0030425 8.92 ADCY10 ADORA1 KCNB1 MAP2

Biological processes related to Brain Ischemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.43 ADORA1 EDN1 NOS2
2 negative regulation of blood pressure GO:0045776 9.37 ADORA1 NOS2
3 regulation of sensory perception of pain GO:0051930 9.32 ADORA1 EDN1
4 positive regulation of cardiac muscle hypertrophy GO:0010613 9.16 EDN1 PARP1
5 regulation of protein complex assembly GO:0043254 8.96 GFAP HSPA8
6 negative regulation of hormone secretion GO:0046888 8.62 ADORA1 EDN1

Molecular functions related to Brain Ischemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heat shock protein binding GO:0031072 8.62 ADORA1 HSPA8

Sources for Brain Ischemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....