MCID: BRN035
MIFTS: 42

Brain Stem Glioma

Categories: Neuronal diseases, Cancer diseases

Aliases & Classifications for Brain Stem Glioma

MalaCards integrated aliases for Brain Stem Glioma:

Name: Brain Stem Glioma 12 14
Brainstem Neuroglial Tumor 12
Glioma of Brainstem 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4202
NCIt 46 C8501
SNOMED-CT 64 444545003
UMLS 69 C0677865

Summaries for Brain Stem Glioma

MalaCards based summary : Brain Stem Glioma, also known as brainstem neuroglial tumor, is related to diffuse intrinsic pontine glioma and glioma. An important gene associated with Brain Stem Glioma is EGFR (Epidermal Growth Factor Receptor), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and ErbB signaling pathway. The drugs Cisplatin and Etoposide have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and bone.

Wikipedia : 72 A brainstem glioma is a cancerous glioma tumor in the brainstem. Around 75% are diagnosed in children... more...

Related Diseases for Brain Stem Glioma

Diseases in the Brain Stem Glioma family:

Adult Brain Stem Glioma

Diseases related to Brain Stem Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 diffuse intrinsic pontine glioma 32.1 H3F3A HIST1H3B
2 glioma 30.4 EGFR H3F3A TP53
3 childhood brain stem glioma 12.6
4 adult brain stem glioma 12.3
5 crigler-najjar syndrome, type ii 10.4 UGT1A UGT1A1
6 crigler-najjar syndrome, type i 10.3 UGT1A UGT1A1
7 asbestos-related lung carcinoma 10.3 EGFR PDGFB
8 irinotecan toxicity 10.1 EGFR UGT1A UGT1A1
9 brain ependymoma 10.1 EGFR TP53
10 squamous cell carcinoma of the larynx 10.0 EGFR TP53
11 microglandular adenosis 10.0 EGFR TP53
12 pulmonary blastoma 10.0 EGFR TP53
13 pleomorphic carcinoma 10.0 EGFR TP53
14 gliomatosis cerebri 10.0 EGFR TP53
15 oropharynx cancer 10.0 EGFR TP53
16 soft tissue sarcoma 10.0 EGFR TP53
17 esophageal basaloid squamous cell carcinoma 10.0 EGFR TP53
18 basaloid squamous cell carcinoma 10.0 EGFR TP53
19 uterine carcinosarcoma 10.0 EGFR TP53
20 hidradenocarcinoma 10.0 EGFR TP53
21 liver angiosarcoma 10.0 TP53 UGT1A1
22 primary peritoneal carcinoma 10.0 EGFR TP53
23 breast metaplastic carcinoma 10.0 EGFR TP53
24 vulva cancer 9.9 EGFR TP53
25 pre-malignant neoplasm 9.9 EGFR TP53
26 mucinous adenocarcinoma 9.9 EGFR TP53
27 cerebral primitive neuroectodermal tumor 9.9 BSG TP53
28 brain glioma 9.9 EGFR TP53
29 bone giant cell sarcoma 9.9 H3F3A TP53
30 glioma susceptibility 1 9.9 H3F3A TP53
31 penile cancer 9.9 EGFR TP53
32 malignant giant cell tumor 9.9 H3F3A TP53
33 in situ carcinoma 9.9 EGFR TP53
34 fibrillary astrocytoma 9.9 H3F3A TP53
35 giant cell glioblastoma 9.9 EGFR TP53
36 lung benign neoplasm 9.8 EGFR TP53
37 pharynx cancer 9.8 EGFR TP53
38 grade iii astrocytoma 9.8 EGFR TP53
39 differentiated thyroid carcinoma 9.7 BSG EGFR TP53
40 larynx cancer 9.7 BSG EGFR TP53
41 adenosquamous carcinoma 9.7 EGFR TP53
42 gastroesophageal reflux 9.7
43 seizures, benign familial neonatal, 1 9.7
44 neurofibromatosis, type iv, of riccardi 9.7
45 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 9.7
46 moyamoya disease 1 9.7
47 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.7
48 hydrocephalus 9.7
49 thrombosis 9.7
50 meningoencephalitis 9.7

Graphical network of the top 20 diseases related to Brain Stem Glioma:



Diseases related to Brain Stem Glioma

Symptoms & Phenotypes for Brain Stem Glioma

Drugs & Therapeutics for Brain Stem Glioma

Drugs for Brain Stem Glioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 282)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
2
Etoposide Approved Phase 3,Phase 2,Phase 1 33419-42-0 36462
3
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
4
Levoleucovorin Approved, Investigational Phase 3,Phase 1 68538-85-2
5
Lomustine Approved, Investigational Phase 3,Phase 1 13010-47-4 3950
6
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
7
Methotrexate Approved Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
8
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
9
Vincristine Approved, Investigational Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
10
Dacarbazine Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 4342-03-4 5351166
11
Temozolomide Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 85622-93-1 5394
12
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
13
Bevacizumab Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 216974-75-3
14
Vorinostat Approved, Investigational Phase 2, Phase 3,Phase 1 149647-78-9 5311
15
Procarbazine Approved, Investigational Phase 3,Phase 1 671-16-9 4915
16
Thioguanine Approved Phase 3 154-42-7 2723601
17
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
18
Donepezil Approved Phase 3,Phase 2,Early Phase 1 120014-06-4 3152
19
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
20
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
21
Ondansetron Approved Phase 3 99614-02-5 4595
22
Cyproheptadine Approved Phase 3,Phase 2 129-03-3 2913
23
Histamine Approved, Investigational Phase 3,Phase 2 51-45-6, 75614-87-8 774
24
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
25
Methylphenidate Approved, Investigational Phase 3 20748-11-2, 113-45-1 4158
26
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
27
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 143 6006
28 Pancreatic Polypeptide Investigational Phase 3,Phase 1 59763-91-6
29 Alkylating Agents Phase 3,Phase 2,Phase 1,Early Phase 1
30 Anti-Inflammatory Agents Phase 3,Phase 2,Phase 1
31 Antimetabolites Phase 3,Phase 2,Phase 1
32 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
33 Antimitotic Agents Phase 3,Phase 2,Phase 1
34 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Phase 1
35 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1,Early Phase 1
36 Antirheumatic Agents Phase 3,Phase 2,Phase 1
37 Calcium, Dietary Phase 3,Phase 2,Phase 1
38 Dermatologic Agents Phase 3,Phase 2,Phase 1,Early Phase 1
39 Etoposide phosphate Phase 3,Phase 2,Phase 1
40 Folic Acid Antagonists Phase 3,Phase 2,Phase 1
41 glucocorticoids Phase 3,Phase 1
42 Hormone Antagonists Phase 3,Phase 2,Phase 1
43 Hormones Phase 3,Phase 2,Phase 1
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
45 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
46 Isophosphamide mustard Phase 3,Phase 1,Phase 2 0
47 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2,Phase 1
48 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1,Early Phase 1
49 Vitamin B Complex Phase 3,Phase 2,Phase 1
50 Angiogenesis Inhibitors Phase 2, Phase 3,Phase 1,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 195)

# Name Status NCT ID Phase Drugs
1 Prospective Trial of Two Hypofractionated Radiotherapy Regimens Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children Unknown status NCT01878266 Phase 3
2 Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas Unknown status NCT00278278 Phase 3 cisplatin;etoposide;ifosfamide;lomustine;methotrexate;prednisone;vincristine sulfate
3 Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children Completed NCT01635140 Phase 3
4 Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma Completed NCT01236560 Phase 2, Phase 3 Temozolomide;Vorinostat
5 Combination Chemotherapy in Treating Children With Progressive Brain Tumors Completed NCT00002944 Phase 3 carboplatin;lomustine;procarbazine hydrochloride;thioguanine;vincristine sulfate
6 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
7 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
8 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
9 Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma Not yet recruiting NCT02864888 Phase 3 Atengenal;Astugenal
10 Study of Antineoplaston Therapy + Radiation vs. Radiation Only in Diffuse, Intrinsic, Brainstem Glioma Not yet recruiting NCT02887040 Phase 3 Atengenal;Astugenal
11 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
12 Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors Terminated NCT00031798 Phase 3 methylphenidate hydrochloride
13 Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma Unknown status NCT00024336 Phase 2 tamoxifen citrate
14 Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma Unknown status NCT00514397 Phase 2 motexafin gadolinium;temozolomide
15 Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas Unknown status NCT01024907 Phase 1, Phase 2
16 A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain Unknown status NCT01403311 Phase 2 5-Aminolevuline Acid
17 Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors Unknown status NCT00281905 Phase 2 carboplatin;cisplatin;cyclophosphamide;methotrexate;vincristine sulfate
18 Antineoplaston Therapy in Treating Patients With Brain Stem Glioma Completed NCT00003459 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
19 Thalomid and Carboplatin for the Treatment of Pediatric Brain Stem Glioma Completed NCT00179881 Phase 2 Carboplatin;Thalomid
20 A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas Completed NCT01118377 Phase 2 Capecitabine
21 Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma Completed NCT00079339 Phase 1, Phase 2 tipifarnib
22 Nimotuzumab and Radiotherapy in Pediatric Patients With Glioma Completed NCT01145170 Phase 2
23 Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma Completed NCT00070525 Phase 2 tipifarnib
24 ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors Completed NCT01756989 Phase 2 Thalidomide, etoposide, celecoxib
25 Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma Completed NCT00381797 Phase 2 Irinotecan Hydrochloride
26 Motexafin Gadolinium and Radiation Therapy in Treating Young Patients With Pontine Glioma Completed NCT00387790 Phase 2 motexafin gadolinium
27 Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas Completed NCT00042991 Phase 1, Phase 2 gefitinib
28 O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors Completed NCT00275002 Phase 2 O6-benzylguanine;temozolomide
29 Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00006102 Phase 2 becatecarin
30 Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma Completed NCT00028795 Phase 2 temozolomide
31 Irinotecan in Treating Patients With Recurrent Glioma Completed NCT00003134 Phase 2 irinotecan hydrochloride
32 Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma Completed NCT00003616 Phase 1, Phase 2 irinotecan hydrochloride
33 Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Glioblastoma Multiforme or Brain Stem Tumors Completed NCT00002619 Phase 2 carboplatin;thiotepa
34 Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor Completed NCT00004068 Phase 2 irinotecan hydrochloride;temozolomide
35 Carboplatin in Patients With Progressive Gliomas Completed NCT00002749 Phase 2 carboplatin
36 Temozolomide in Treating Patients With Progressive Low-Grade Glioma Completed NCT00003466 Phase 2 temozolomide
37 Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas Completed NCT01574092 Phase 2 Combination of two marketed drugs (irinotecan and cisplatin)
38 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2 bevacizumab;placebo
39 Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors Completed NCT00095940 Phase 1, Phase 2 lapatinib ditosylate
40 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
41 Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors Completed NCT00002608 Phase 2 cisplatin;doxorubicin hydrochloride;tamoxifen citrate
42 Phenylacetate in Treating Children With Recurrent or Progressive Brain Tumors Completed NCT00003241 Phase 2 phenylacetate
43 Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment Completed NCT00091182 Phase 2 oxaliplatin
44 Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment Completed NCT00066248 Phase 2 cyproheptadine hydrochloride;megestrol acetate
45 Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors Completed NCT00005952 Phase 1, Phase 2 temozolomide
46 Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma Completed NCT00003467 Phase 2 carmustine;polifeprosan 20 with carmustine implant
47 A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas Completed NCT00036569 Phase 2
48 Antineoplaston Therapy in Treating Patients With Brain Tumors Completed NCT00003457 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
49 Antineoplaston Therapy in Treating Children With Brain Tumors Completed NCT00003458 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
50 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors Completed NCT00003478 Phase 1, Phase 2

Search NIH Clinical Center for Brain Stem Glioma

Genetic Tests for Brain Stem Glioma

Anatomical Context for Brain Stem Glioma

MalaCards organs/tissues related to Brain Stem Glioma:

38
Brain, Spinal Cord, Bone, Liver, Bone Marrow, T Cells, Endothelial

Publications for Brain Stem Glioma

Articles related to Brain Stem Glioma:

(show top 50) (show all 57)
# Title Authors Year
1
Spontaneous complete regression of a brain stem glioma pathologically diagnosed as a high-grade glioma. ( 28808781 )
2017
2
Brain stem glioma with spinal cord involvement in a young with neurofibromatosis type 1. ( 24614250 )
2014
3
Intracranial syphilitic gumma mimicking a brain stem glioma. ( 22723064 )
2012
4
Treatment of progressive brain stem glioma with bevacizumab: radiological, metabolic and histopathological aspects. ( 22048887 )
2012
5
Shall we treat hydrocephalus associated to brain stem glioma in children? ( 21928037 )
2011
6
Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium. ( 21233173 )
2011
7
Diffuse brain stem glioma. ( 20212241 )
2010
8
DTI fiber tracking to differentiate demyelinating diseases from diffuse brain stem glioma. ( 20363335 )
2010
9
Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas. ( 18324354 )
2008
10
Commentary on diffuse brain stem glioma in children. ( 19016114 )
2008
11
Brain stem glioma, a rare cause of hearing loss and dysequilibrium. ( 21063295 )
2008
12
Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: a Children's Oncology Group phase II study. ( 17278121 )
2008
13
Somatostatin-receptor positive brain stem glioma visualized by octreoscan. ( 17627256 )
2007
14
HSV encephalitis in a child with brain stem glioma: a rare complication of therapy. Case report and review of the neurosurgical literature. ( 17593375 )
2007
15
Brain stem glioma: two case studies. ( 15695354 )
2005
16
Irinotecan therapy in a 12-year-old girl with recurrent brain stem glioma and without functional polymorphisms in UGT1A1 activity: case report. ( 16187025 )
2005
17
Biopsy of brain stem glioma using motor-evoked potential mapping by direct peduncular stimulation and individual adjuvant therapy. Case report. ( 15699622 )
2005
18
ERBB1 is amplified and overexpressed in high-grade diffusely infiltrative pediatric brain stem glioma. ( 14506149 )
2003
19
Brain stem glioma in a child: false diagnosis of radiation necrosis with FDG PET. ( 12555260 )
2003
20
Recurrent haemorrhage from a malignant brain stem glioma: a review of the mechanisms of tumoural haemorrhage. ( 12948477 )
2003
21
Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma: a preliminary report. ( 12718563 )
2003
22
Childhood Brain Stem Glioma Treatment (PDQAr): Health Professional Version ( 27227258 )
2002
23
Childhood Brain Stem Glioma Treatment (PDQAr): Health Professional Version ( 27010061 )
2002
24
Childhood Brain Stem Glioma Treatment (PDQAr): Patient Version ( 26389295 )
2002
25
Childhood Brain Stem Glioma Treatment (PDQAr): Patient Version ( 27227262 )
2002
26
Childhood Brain Stem Glioma Treatment (PDQAr): Health Professional Version ( 26389253 )
2002
27
Moyamoya disease associated with a brain stem glioma. ( 10855525 )
2000
28
Clinical management of brain stem glioma. ( 10332008 )
1999
29
Brain stem glioma--a study of 111 patients. ( 10921213 )
1999
30
Diffuse brain stem glioma. A review of stereotactic biopsies. ( 10392494 )
1999
31
Neuroimaging of pediatric brain stem diseases other than brain stem glioma. ( 9075252 )
1996
32
Bilateral jawline nodules in a child with a brain-stem glioma. Poststeroid panniculitis. ( 7492138 )
1995
33
Leptomyxid amebic meningoencephalitis mimicking brain stem glioma. ( 7611076 )
1995
34
Quality of survival among children treated for brain stem glioma. ( 8043460 )
1994
35
Intra-arterial chemotherapy for brain stem glioma: report of four cases. ( 8108006 )
1994
36
Brain-stem glioma growth patterns. ( 8433142 )
1993
37
Radiotherapy for pediatric brain stem glioma: radiation dose, response, and survival. ( 1407449 )
1992
38
Pathological laughter and brain stem glioma. ( 1640246 )
1992
39
Reversible neurotoxicity following hyperfractionated radiation therapy of brain stem glioma. ( 1902547 )
1991
40
Prolonged response to carboplatin in an infant with brain stem glioma. ( 1985722 )
1991
41
Brain stem glioma: the role of a biopsy. ( 1892569 )
1991
42
A case of dyschondroplasia associated with brain stem glioma: diagnosis by stereotactic biopsy. ( 2234348 )
1990
43
Nursing care of the child with a brain stem glioma. ( 2254841 )
1990
44
Chronic dysphagia, vomiting and gastroesophageal reflux as manifestations of a brain stem glioma: a case report. ( 2488955 )
1989
45
Hyperfractionated radiation therapy for brain-stem glioma: a phase I-II trial. ( 2709109 )
1989
46
Brain stem glioma mimicking progressive basilar artery thrombosis. ( 2834522 )
1988
47
Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials. ( 3054620 )
1988
48
Brain stem glioma presenting as gastro-oesophageal reflux. ( 3632023 )
1987
49
Orthostatic hypotension with lower brain stem glioma. ( 7161610 )
1982
50
Brain stem glioma in childhood: acute hemiplegic onset. ( 6269714 )
1981

Variations for Brain Stem Glioma

Expression for Brain Stem Glioma

Search GEO for disease gene expression data for Brain Stem Glioma.

Pathways for Brain Stem Glioma

GO Terms for Brain Stem Glioma

Cellular components related to Brain Stem Glioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear nucleosome GO:0000788 8.96 H3F3A HIST1H3B
2 protein complex GO:0043234 8.92 EGFR H3F3A HIST1H3B TP53

Biological processes related to Brain Stem Glioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of DNA replication GO:0045740 9.46 EGFR PDGFB
2 chromatin silencing at rDNA GO:0000183 9.43 H3F3A HIST1H3B
3 cellular response to estradiol stimulus GO:0071392 9.4 EGFR UGT1A1
4 cellular response to reactive oxygen species GO:0034614 9.37 EGFR TP53
5 positive regulation of reactive oxygen species metabolic process GO:2000379 9.32 PDGFB TP53
6 telomere organization GO:0032200 9.26 H3F3A HIST1H3B
7 embryonic placenta development GO:0001892 9.16 EGFR PDGFB
8 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 8.96 PDGFB TP53
9 response to organic cyclic compound GO:0014070 8.8 EGFR TP53 UGT1A1

Molecular functions related to Brain Stem Glioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cadherin binding GO:0045296 9.33 BSG EGFR HIST1H3B
2 protein heterodimerization activity GO:0046982 9.1 EGFR H3F3A HIST1H3B PDGFB TP53 UGT1A1
3 nucleosomal DNA binding GO:0031492 8.96 H3F3A HIST1H3B

Sources for Brain Stem Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
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30 HMDB
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33 ICD10 via Orphanet
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36 KEGG
37 LifeMap
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41 MeSH
42 MESH via Orphanet
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54 OMIM via Orphanet
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60 QIAGEN
65 SNOMED-CT via HPO
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67 TGDB
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