MCID: BRN035
MIFTS: 39

Brain Stem Glioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Brain Stem Glioma

MalaCards integrated aliases for Brain Stem Glioma:

Name: Brain Stem Glioma 12 14
Brainstem Neuroglial Tumor 12
Glioma of Brainstem 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4202
NCIt 47 C8501
SNOMED-CT 64 444545003
UMLS 69 C0677865

Summaries for Brain Stem Glioma

MalaCards based summary : Brain Stem Glioma, also known as brainstem neuroglial tumor, is related to childhood brain stem glioma and adult brain stem glioma. An important gene associated with Brain Stem Glioma is EGFR (Epidermal Growth Factor Receptor), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Transcriptional misregulation in cancer. The drugs Cisplatin and Etoposide have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and bone.

Wikipedia : 72 A brainstem glioma is a cancerous glioma tumor in the brainstem. Around 75% are diagnosed in children... more...

Related Diseases for Brain Stem Glioma

Diseases in the Brain Stem Glioma family:

Adult Brain Stem Glioma

Diseases related to Brain Stem Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
id Related Disease Score Top Affiliating Genes
1 childhood brain stem glioma 12.5
2 adult brain stem glioma 12.1
3 diffuse intrinsic pontine glioma 11.3
4 hyperbilirubinemia, familial transient neonatal 10.5 UGT1A UGT1A1
5 glioma 10.5
6 crigler-najjar syndrome, type ii 10.5 UGT1A UGT1A1
7 pediatric infratentorial ependymoma 10.3 EGFR TP53
8 hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 10.3 EGFR TP53
9 breast fibrosarcoma 10.3 EGFR TP53
10 congenital mesoblastic nephroma 10.3 EGFR TP53
11 extragonadal nonseminomatous germ cell tumor 10.3 EGFR TP53
12 lymphopenia 10.3 EGFR TP53
13 multiple carboxylase deficiency 10.3 EGFR TP53
14 sparse hair ptosis mental retardation 10.3 EGFR TP53
15 middle ear squamous cell carcinoma 10.3 EGFR TP53
16 spinal cord dermoid cyst 10.3 EGFR TP53
17 raltegravir toxicity 10.3 EGFR UGT1A UGT1A1
18 hip subluxation 10.3 EGFR TP53
19 distal monosomy 7q36 10.2 EGFR TP53
20 secondary hyperparathyroidism of renal origin 10.2 EGFR TP53
21 ossifying fibromyxoid tumor 10.2 TP53 UGT1A1
22 rectum kaposi's sarcoma 10.2 EGFR TP53
23 molluscum contagiosum 10.2 EGFR TP53
24 lacrimal gland mucoepidermoid carcinoma 10.2 EGFR TP53
25 ductal carcinoma in situ 10.2 EGFR TP53
26 vulvar keratoacanthoma-like carcinoma 10.2 BSG TP53
27 cecum adenocarcinoma 10.2 EGFR TP53
28 brain edema 10.1 H3F3A TP53
29 cervical benign neoplasm 10.1 EGFR TP53
30 congenital disorder of glycosylation, type if 10.1 H3F3A TP53
31 hemangioma of liver 10.1 H3F3A TP53
32 stomach disease 10.1 EGFR PDGFB
33 myxedema 10.1 EGFR TP53
34 schwannoma of jugular foramen 10.1 H3F3A TP53
35 anaerobic pneumonia 10.1 EGFR TP53
36 juvenile astrocytoma 10.1 EGFR TP53
37 olfactory neuroblastoma 10.0 EGFR TP53
38 integumentary system cancer 10.0 EGFR TP53
39 non-distal trisomy 10q 9.9 BSG EGFR TP53
40 hepatic flexure cancer 9.9 BSG EGFR TP53
41 cystic lymphangioma 9.9 EGFR TP53
42 fallopian tube mucinous tumor 9.9 EGFR TP53
43 cervical cancer, somatic 9.9 BSG EGFR TP53
44 sebaceous adenocarcinoma 9.8 EGFR TP53
45 prostate adenoid cystic carcinoma 9.7 BSG H3F3A TP53
46 gastroesophageal reflux 9.7
47 neurofibromatosis, type 1 9.7
48 moyamoya disease 9.7
49 hydrocephalus 9.7
50 thrombosis 9.7

Graphical network of the top 20 diseases related to Brain Stem Glioma:



Diseases related to Brain Stem Glioma

Symptoms & Phenotypes for Brain Stem Glioma

Drugs & Therapeutics for Brain Stem Glioma

Drugs for Brain Stem Glioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 292)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
2
Etoposide Approved Phase 3,Phase 2,Phase 1 33419-42-0 36462
3
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
4
Levoleucovorin Approved Phase 3,Phase 1 68538-85-2
5
Lomustine Approved Phase 3,Phase 1 13010-47-4 3950
6
Mechlorethamine Approved Phase 3,Phase 1,Phase 2 51-75-2 4033
7
Methotrexate Approved Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
8
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
9
Vincristine Approved, Investigational Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
10
Dacarbazine Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 4342-03-4 5351166
11
Temozolomide Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 85622-93-1 5394
12
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
13
Bevacizumab Approved, Investigational Phase 2, Phase 3,Phase 1,Early Phase 1 216974-75-3
14
Vorinostat Approved, Investigational Phase 2, Phase 3,Phase 1 149647-78-9 5311
15
Procarbazine Approved Phase 3,Phase 1 671-16-9 4915
16
Thioguanine Approved Phase 3 154-42-7 2723601
17
Donepezil Approved Phase 3,Phase 2,Early Phase 1 120014-06-4 3152
18
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
19
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
20
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
21
Ondansetron Approved Phase 3 99614-02-5 4595
22
Cyproheptadine Approved Phase 3,Phase 2 129-03-3 2913
23
Histamine Approved, Investigational Phase 3,Phase 2 75614-87-8, 51-45-6 774
24
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
25
Methylphenidate Approved, Investigational Phase 3 113-45-1 4158
26
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
27
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 143 6006
28 Pancreatic Polypeptide Investigational Phase 3,Phase 1 59763-91-6
29 Alkylating Agents Phase 3,Phase 2,Phase 1,Early Phase 1
30 Anti-Inflammatory Agents Phase 3,Phase 2,Phase 1
31 Antimetabolites Phase 3,Phase 2,Phase 1
32 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
33 Antimitotic Agents Phase 3,Phase 2,Phase 1
34 Antineoplastic Agents, Hormonal Phase 3,Phase 2,Phase 1
35 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1,Early Phase 1
36 Antirheumatic Agents Phase 3,Phase 2,Phase 1
37 Calcium, Dietary Phase 3,Phase 2,Phase 1
38 Dermatologic Agents Phase 3,Phase 2,Phase 1,Early Phase 1
39 Etoposide phosphate Phase 3,Phase 2,Phase 1
40 Folic Acid Antagonists Phase 3,Phase 2,Phase 1
41 glucocorticoids Phase 3,Phase 1
42 Hormone Antagonists Phase 3,Phase 2,Phase 1
43 Hormones Phase 3,Phase 2,Phase 1
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
45 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
46 Isophosphamide mustard Phase 3,Phase 1,Phase 2
47 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2,Phase 1
48 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1,Early Phase 1
49 Vitamin B Complex Phase 3,Phase 2,Phase 1
50 Angiogenesis Inhibitors Phase 2, Phase 3,Phase 1,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 203)

id Name Status NCT ID Phase Drugs
1 Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas Unknown status NCT00278278 Phase 3 cisplatin;etoposide;ifosfamide;lomustine;methotrexate;prednisone;vincristine sulfate
2 Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children Completed NCT01635140 Phase 3
3 Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma Completed NCT01236560 Phase 2, Phase 3 Temozolomide;Vorinostat
4 Combination Chemotherapy in Treating Children With Progressive Brain Tumors Completed NCT00002944 Phase 3 carboplatin;lomustine;procarbazine hydrochloride;thioguanine;vincristine sulfate
5 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
6 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
7 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
8 Prospective Trial of Two Hypofractionated Radiotherapy Regimens Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children Recruiting NCT01878266 Phase 3
9 Effect of Antineoplaston Therapy on the QT/QTc Interval In Subjects With Diffuse, Intrinsic, Brainstem Glioma Not yet recruiting NCT02864888 Phase 3 Atengenal;Astugenal
10 Study of Antineoplaston Therapy + Radiation vs. Radiation Only in Diffuse, Intrinsic, Brainstem Glioma Not yet recruiting NCT02887040 Phase 3 Atengenal;Astugenal
11 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
12 Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors Terminated NCT00031798 Phase 3 methylphenidate hydrochloride
13 Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma Unknown status NCT00024336 Phase 2 tamoxifen citrate
14 Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma Unknown status NCT00514397 Phase 2 motexafin gadolinium;temozolomide
15 A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain Unknown status NCT01403311 Phase 2 5-Aminolevuline Acid
16 Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors Unknown status NCT00281905 Phase 2 carboplatin;cisplatin;cyclophosphamide;methotrexate;vincristine sulfate
17 Antineoplaston Therapy in Treating Patients With Brain Stem Glioma Completed NCT00003459 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
18 Thalomid and Carboplatin for the Treatment of Pediatric Brain Stem Glioma Completed NCT00179881 Phase 2 Carboplatin;Thalomid
19 A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas Completed NCT01118377 Phase 2 Capecitabine
20 Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma Completed NCT00079339 Phase 1, Phase 2 tipifarnib
21 Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma Completed NCT00070525 Phase 2 tipifarnib
22 Nimotuzumab and Radiotherapy in Pediatric Patients With Glioma Completed NCT01145170 Phase 2
23 Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma Completed NCT00381797 Phase 2 Irinotecan Hydrochloride
24 ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors Completed NCT01756989 Phase 2 Thalidomide, etoposide, celecoxib
25 Motexafin Gadolinium and Radiation Therapy in Treating Young Patients With Pontine Glioma Completed NCT00387790 Phase 2 motexafin gadolinium
26 Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas Completed NCT00042991 Phase 1, Phase 2 gefitinib
27 O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors Completed NCT00275002 Phase 2 O6-benzylguanine;temozolomide
28 Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00006102 Phase 2 becatecarin
29 Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma Completed NCT00028795 Phase 2 temozolomide
30 Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Glioblastoma Multiforme or Brain Stem Tumors Completed NCT00002619 Phase 2 carboplatin;thiotepa
31 A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas Completed NCT00036569 Phase 2
32 Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma Completed NCT00003616 Phase 1, Phase 2 irinotecan hydrochloride
33 Irinotecan in Treating Patients With Recurrent Glioma Completed NCT00003134 Phase 2 irinotecan hydrochloride
34 Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor Completed NCT00004068 Phase 2 irinotecan hydrochloride;temozolomide
35 Carboplatin in Patients With Progressive Gliomas Completed NCT00002749 Phase 2 carboplatin
36 Temozolomide in Treating Patients With Progressive Low-Grade Glioma Completed NCT00003466 Phase 2 temozolomide
37 Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas Completed NCT01574092 Phase 2 Combination of two marketed drugs (irinotecan and cisplatin)
38 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2 bevacizumab;placebo
39 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
40 Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors Completed NCT00095940 Phase 1, Phase 2 lapatinib ditosylate
41 Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma Completed NCT00003467 Phase 2 carmustine;polifeprosan 20 with carmustine implant
42 Phenylacetate in Treating Children With Recurrent or Progressive Brain Tumors Completed NCT00003241 Phase 2 phenylacetate
43 Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors Completed NCT00005952 Phase 1, Phase 2 temozolomide
44 Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors Completed NCT00002608 Phase 2 cisplatin;doxorubicin hydrochloride;tamoxifen citrate
45 Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment Completed NCT00091182 Phase 2 oxaliplatin
46 Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment Completed NCT00066248 Phase 2 cyproheptadine hydrochloride;megestrol acetate
47 Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma Completed NCT00498927 Phase 2 temozolomide
48 Antineoplaston Therapy in Treating Children With Brain Tumors Completed NCT00003458 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
49 Talampanel in Treating Patients With Recurrent High-Grade Glioma Completed NCT00064363 Phase 2 talampanel
50 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors Completed NCT00003478 Phase 1, Phase 2

Search NIH Clinical Center for Brain Stem Glioma

Genetic Tests for Brain Stem Glioma

Anatomical Context for Brain Stem Glioma

MalaCards organs/tissues related to Brain Stem Glioma:

39
Brain, Spinal Cord, Bone, Liver, Bone Marrow, T Cells, Endothelial

Publications for Brain Stem Glioma

Articles related to Brain Stem Glioma:

(show top 50) (show all 57)
id Title Authors Year
1
Spontaneous complete regression of a brain stem glioma pathologically diagnosed as a high-grade glioma. ( 28808781 )
2017
2
Brain stem glioma with spinal cord involvement in a young with neurofibromatosis type 1. ( 24614250 )
2014
3
Treatment of progressive brain stem glioma with bevacizumab: radiological, metabolic and histopathological aspects. ( 22048887 )
2012
4
Intracranial syphilitic gumma mimicking a brain stem glioma. ( 22723064 )
2012
5
Shall we treat hydrocephalus associated to brain stem glioma in children? ( 21928037 )
2011
6
Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium. ( 21233173 )
2011
7
DTI fiber tracking to differentiate demyelinating diseases from diffuse brain stem glioma. ( 20363335 )
2010
8
Diffuse brain stem glioma. ( 20212241 )
2010
9
Brain stem glioma, a rare cause of hearing loss and dysequilibrium. ( 21063295 )
2008
10
Commentary on diffuse brain stem glioma in children. ( 19016114 )
2008
11
Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas. ( 18324354 )
2008
12
Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: a Children's Oncology Group phase II study. ( 17278121 )
2008
13
HSV encephalitis in a child with brain stem glioma: a rare complication of therapy. Case report and review of the neurosurgical literature. ( 17593375 )
2007
14
Somatostatin-receptor positive brain stem glioma visualized by octreoscan. ( 17627256 )
2007
15
Biopsy of brain stem glioma using motor-evoked potential mapping by direct peduncular stimulation and individual adjuvant therapy. Case report. ( 15699622 )
2005
16
Brain stem glioma: two case studies. ( 15695354 )
2005
17
Irinotecan therapy in a 12-year-old girl with recurrent brain stem glioma and without functional polymorphisms in UGT1A1 activity: case report. ( 16187025 )
2005
18
Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma: a preliminary report. ( 12718563 )
2003
19
Recurrent haemorrhage from a malignant brain stem glioma: a review of the mechanisms of tumoural haemorrhage. ( 12948477 )
2003
20
ERBB1 is amplified and overexpressed in high-grade diffusely infiltrative pediatric brain stem glioma. ( 14506149 )
2003
21
Brain stem glioma in a child: false diagnosis of radiation necrosis with FDG PET. ( 12555260 )
2003
22
Childhood Brain Stem Glioma Treatment (PDQAr): Patient Version ( 26389295 )
2002
23
Childhood Brain Stem Glioma Treatment (PDQAr): Health Professional Version ( 27227258 )
2002
24
Childhood Brain Stem Glioma Treatment (PDQAr): Health Professional Version ( 26389253 )
2002
25
Childhood Brain Stem Glioma Treatment (PDQAr): Health Professional Version ( 27010061 )
2002
26
Childhood Brain Stem Glioma Treatment (PDQAr): Patient Version ( 27227262 )
2002
27
Moyamoya disease associated with a brain stem glioma. ( 10855525 )
2000
28
Diffuse brain stem glioma. A review of stereotactic biopsies. ( 10392494 )
1999
29
Clinical management of brain stem glioma. ( 10332008 )
1999
30
Brain stem glioma--a study of 111 patients. ( 10921213 )
1999
31
Neuroimaging of pediatric brain stem diseases other than brain stem glioma. ( 9075252 )
1996
32
Leptomyxid amebic meningoencephalitis mimicking brain stem glioma. ( 7611076 )
1995
33
Bilateral jawline nodules in a child with a brain-stem glioma. Poststeroid panniculitis. ( 7492138 )
1995
34
Quality of survival among children treated for brain stem glioma. ( 8043460 )
1994
35
Intra-arterial chemotherapy for brain stem glioma: report of four cases. ( 8108006 )
1994
36
Brain-stem glioma growth patterns. ( 8433142 )
1993
37
Pathological laughter and brain stem glioma. ( 1640246 )
1992
38
Radiotherapy for pediatric brain stem glioma: radiation dose, response, and survival. ( 1407449 )
1992
39
Prolonged response to carboplatin in an infant with brain stem glioma. ( 1985722 )
1991
40
Reversible neurotoxicity following hyperfractionated radiation therapy of brain stem glioma. ( 1902547 )
1991
41
Brain stem glioma: the role of a biopsy. ( 1892569 )
1991
42
A case of dyschondroplasia associated with brain stem glioma: diagnosis by stereotactic biopsy. ( 2234348 )
1990
43
Nursing care of the child with a brain stem glioma. ( 2254841 )
1990
44
Hyperfractionated radiation therapy for brain-stem glioma: a phase I-II trial. ( 2709109 )
1989
45
Chronic dysphagia, vomiting and gastroesophageal reflux as manifestations of a brain stem glioma: a case report. ( 2488955 )
1989
46
Brain stem glioma mimicking progressive basilar artery thrombosis. ( 2834522 )
1988
47
Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials. ( 3054620 )
1988
48
Brain stem glioma presenting as gastro-oesophageal reflux. ( 3632023 )
1987
49
Orthostatic hypotension with lower brain stem glioma. ( 7161610 )
1982
50
Brain stem glioma in childhood: acute hemiplegic onset. ( 6269714 )
1981

Variations for Brain Stem Glioma

Expression for Brain Stem Glioma

Search GEO for disease gene expression data for Brain Stem Glioma.

Pathways for Brain Stem Glioma

GO Terms for Brain Stem Glioma

Cellular components related to Brain Stem Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 nuclear nucleosome GO:0000788 8.96 H3F3A HIST1H3B
2 protein complex GO:0043234 8.8 H3F3A HIST1H3B TP53

Biological processes related to Brain Stem Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 embryo implantation GO:0007566 9.46 BSG H3F3A
2 positive regulation of DNA replication GO:0045740 9.43 EGFR PDGFB
3 cellular response to estradiol stimulus GO:0071392 9.4 EGFR UGT1A1
4 chromatin silencing at rDNA GO:0000183 9.37 H3F3A HIST1H3B
5 positive regulation of reactive oxygen species metabolic process GO:2000379 9.32 PDGFB TP53
6 telomere organization GO:0032200 9.26 H3F3A HIST1H3B
7 embryonic placenta development GO:0001892 9.16 EGFR PDGFB
8 positive regulation of pri-miRNA transcription from RNA polymerase II promoter GO:1902895 8.96 PDGFB TP53
9 phosphatidylinositol-mediated signaling GO:0048015 8.8 EGFR PDGFB TP53

Molecular functions related to Brain Stem Glioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cadherin binding GO:0045296 9.33 BSG EGFR HIST1H3B
2 protein heterodimerization activity GO:0046982 9.1 EGFR H3F3A HIST1H3B PDGFB TP53 UGT1A1
3 nucleosomal DNA binding GO:0031492 8.65 H3F3A

Sources for Brain Stem Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
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48 NDF-RT
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52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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