MCID: BRN026
MIFTS: 41

Branch Retinal Artery Occlusion malady

Summaries for Branch Retinal Artery Occlusion

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63Wikipedia, 32MalaCards
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Wikipedia:63 Branch retinal artery occlusion (BRAO) is a rare retinal vascular disorder in which one of the branches... more...

MalaCards: Branch Retinal Artery Occlusion, also known as retinal arterial branch occlusion, is related to retinal vein occlusion and vasculitis. An important gene associated with Branch Retinal Artery Occlusion is ROM1 (retinal outer segment membrane protein 1), and among its related pathways are Formation of Fibrin Clot (Clotting Cascade) and Common Pathway. The compounds warfarin and fluorescein have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and thyroid, and related mouse phenotypes are vision/eye and cardiovascular system.

Aliases & Classifications for Branch Retinal Artery Occlusion

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8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 39NCIt, 56SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

branch retinal artery occlusion 8 10 60
retinal arterial branch occlusion 8
arterial retinal branch occlusion 8


External Ids:

Disease Ontology8 DOID:13094
MeSH34 D015356
SNOMED-CT56 50821009
NCIt39 C34436
ICD9CM27 362.32

Related Diseases for Branch Retinal Artery Occlusion

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Branch Retinal Artery Occlusion via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 119)
idRelated DiseaseScoreTop Affiliating Genes
1retinal vein occlusion30.9F5, MTHFR, SERPINC1
2vasculitis30.6TNF
3central retinal vein occlusion30.6MTHFR, F5
4antiphospholipid syndrome30.5F5, MTHFR, SERPINC1
5hyperhomocysteinemia30.5F5, MTHFR, SERPINC1
6retinal vascular occlusion30.3F5
7patent foramen ovale30.3F5
8migraine30.3MTHFR
9crohn's disease30.3TNF
10protein s deficiency30.3SERPINC1, F5
11thrombophilia30.3SERPINC1, MTHFR, F5
12retinal artery occlusion11.3
13retinitis11.3
14central retinal artery occlusion10.8
15retinal disease10.7
16carotid artery occlusion10.6
17carotid stenosis10.4
18neovascular glaucoma10.4
19hepatitis c10.4
20ischemic neuropathy10.4
21carotid artery dissection10.4
22ischemic optic neuropathy10.4
23retinal vasculitis10.4
24glaucoma10.4
25hepatitis10.4
26neuritis10.4
27neuropathy10.4
28optic neuritis10.4
29thyroiditis10.4
30deficiency anemia10.2
31rheumatic fever10.2
32neuroretinitis10.2
33pseudotumor cerebri10.2
34papillary carcinoma10.2
35choroiditis10.2
36posterior scleritis10.2
37arteriovenous malformation10.2
38cavernous sinus thrombosis10.2
39retinitis pigmentosa10.2
40iron deficiency anemia10.2
41lyme disease10.2
42acquired immunodeficiency syndrome10.2
43transient retinal arterial occlusion10.2
44churg-strauss syndrome10.2
45posterior uveitis10.2
46hepatitis a10.2
47adenocarcinoma10.2
48astrocytoma10.2
49central nervous system vasculitis10.2
50cervicitis10.2

Graphical network of the top 20 diseases related to Branch Retinal Artery Occlusion:



Diseases related to branch retinal artery occlusion

Clinical Features for Branch Retinal Artery Occlusion

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Drugs & Therapeutics for Branch Retinal Artery Occlusion

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Branch Retinal Artery Occlusion

Search CenterWatch for Branch Retinal Artery Occlusion

Genetic Tests for Branch Retinal Artery Occlusion

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Anatomical Context for Branch Retinal Artery Occlusion

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32MalaCards
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MalaCards organs/tissues related to Branch Retinal Artery Occlusion:

32
Eye, Retina, Thyroid

Animal Models for Branch Retinal Artery Occlusion or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Branch Retinal Artery Occlusion:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000539110.1ROM1
2MP:00053859.3ERG, ROM1
3MP:00036317.5SERPINC1, ERG, ROM1, MTHFR, F5, TNF

Publications for Branch Retinal Artery Occlusion

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50PubMed
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Articles related to Branch Retinal Artery Occlusion:

(show top 50)    (show all 129)
idTitleAuthorsYear
1
Simultaneous vitreous hemorrhage and branch retinal artery occlusion after prepapillary arterial loop rupture. (23410854)
2013
2
Neovascular glaucoma due to branch retinal vein occlusion combined with branch retinal artery occlusion. (23372385)
2013
3
Branch retinal artery occlusion associated with posterior uveitis. (23514435)
2013
4
Branch retinal artery occlusion associated with photodynamic therapy in a circumscribed choroidal haemangioma. (24284121)
2013
5
Branch retinal artery occlusion and central retinal vein occlusion associated with pegylated interferon plus ribavirin combination therapy for chronic hepatitis C. (22172047)
2012
6
Evidence of recurrent microvascular occlusions associated with acute branch retinal artery occlusion demonstrated with spectral-domain optical coherence tomography. (22869026)
2012
7
In vivo identification of alteration of inner neurosensory layers in branch retinal artery occlusion. (21515559)
2012
8
Transcorneal electrical stimulation improves visual function in eyes with branch retinal artery occlusion. (21499563)
2011
9
Optic disc macroaneurysm in evolution: from incidental finding to branch retinal artery occlusion and spontaneous resolution. (21427799)
2011
10
Branch retinal artery occlusion following elective percutaneous coronary intervention. (21266366)
2011
11
Branch retinal artery occlusion (BRAO). (21717927)
2011
12
Concurrent central retinal artery occlusion and branch retinal vein occlusion in giant cell arteritis. (20668717)
2010
13
Branch retinal artery occlusion with visual field and multifocal erg in Susac syndrome: a case report. (20740301)
2010
14
Posterior scleritis presenting with simultaneous branch retinal artery occlusion and exudative retinal detachment. (18617904)
2009
15
Restoration of retinal blood flow via translumenal Nd:YAG embolysis/embolectomy for central and branch retinal artery occlusion. (19202430)
2009
16
Branch retinal vein occlusion followed by central retinal artery occlusion in Churg-Strauss syndrome: unusual ocular manifestations in allergic granulomatous angiitis. (19253257)
2009
17
Restoration of retinal blood flow via translumenal Nd:YAG embolysis/embolectomy (TYL/E) for central and branch retinal artery occlusion. (19430398)
2008
18
Branch retinal artery occlusion after injection of a long-acting risperidone preparation. (17709768)
2007
19
Branch retinal artery occlusion during a migraine attack. (17697184)
2007
20
A case of branch retinal artery occlusion associated with presumed optic neuritis. (16897231)
2006
21
Optical coherence tomography findings in branch retinal artery occlusion. (16703561)
2006
22
Branch retinal artery occlusions as the presenting feature of primary central nervous system vasculitis. (15675139)
2004
23
Branch retinal artery occlusion following embolization of a maxillary sinus tumor. (15623139)
2003
24
Translumenal Nd:YAG laser embolysis for branch retinal artery occlusion. (11927856)
2002
25
Primary antiphospholipid syndrome presenting with a branch retinal artery occlusion in a 15-year-old boy. (12150590)
2002
26
Bilateral prepapillary loops with unilateral branch retinal artery occlusion following thrombus at the loop apex. (11217933)
2001
27
Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease. (12201349)
2001
28
Thrombophilia as a cause for central and branch retinal artery occlusion in patients without an apparent embolic source. (11767028)
2001
29
Branch retinal artery occlusion secondary to a Hollenhorst plaque. (11256349)
2000
30
Branch retinal artery occlusion: a case complicating acute rheumatic fever and dental abscess. (10953747)
2000
31
Branch retinal artery occlusion: angiographic demonstration of increased retinal blood flow after external carotid endarterectomy. (10088062)
1999
32
Branch retinal artery occlusion in systemic diseases: a case report. (10355155)
1999
33
Bilateral anterior ischemic optic neuropathy and branch retinal artery occlusion after radical prostatectomy. (10492208)
1999
34
Bartonella henselae infection associated with peripapillary angioma, branch retinal artery occlusion, and severe vision loss. (10030575)
1999
35
Delayed branch retinal artery occlusion following presumed blunt common carotid dissection. (9715701)
1998
36
Branch retinal artery occlusion in a child. (8913134)
1996
37
Branch retinal artery occlusion as the initial sign of giant cell arteritis. (8794719)
1996
38
Branch retinal artery occlusion in pregnancy. (8297878)
1994
39
Branch retinal artery occlusion following thyroidectomy for papillary carcinoma of the thyroid: report of a case. (8400682)
1993
40
Branch retinal artery occlusion. A possible adverse effect of chelation therapy. (8492825)
1993
41
Visual loss in pseudotumor cerebri from branch retinal artery occlusion. (1543231)
1992
42
Anterior ischemic optic neuropathy and branch retinal artery occlusion in cavernous sinus thrombosis. (2144537)
1990
43
Branch retinal artery occlusion secondary to percutaneous transluminal coronary angioplasty. (2523726)
1989
44
Retinitis pigmentosa and branch retinal artery occlusion with anticardiolipin antibody. Case report. (2923554)
1989
45
Branch retinal-artery occlusion in acquired immunodeficiency syndrome prodrome. (3408084)
1988
46
Disappearance of myelinated retinal nerve fibers after a branch retinal artery occlusion. (3591888)
1987
47
Branch retinal artery occlusion and carotid artery stenosis. (3826289)
1987
48
Branch retinal artery occlusion after dye yellow photocoagulation of an arterial macroaneurysm. (3618718)
1987
49
Ocular neovascularization with retinal vascular occlusion. II. Occurrence in central and branch retinal artery occlusion. (6182865)
1982
50
Correlation of clinicopathologic findings in a patient. Congenital night blindness, branch retinal vein occlusion, cilioretinal artery, drusen of the optic nerve head, and intraretinal pigmented lesion. (309759)
1978

Genetic Variations for Branch Retinal Artery Occlusion

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Expression for genes affiliated with Branch Retinal Artery Occlusion

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Branch Retinal Artery Occlusion

Search GEO for disease gene expression data for Branch Retinal Artery Occlusion.

Pathways for genes affiliated with Branch Retinal Artery Occlusion

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53Reactome, 52R&D Systems, 37NCBI BioSystems Database, 51QIAGEN
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Pathways related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.6SERPINC1, F5
2
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9.6SERPINC1, F5

Compounds for genes affiliated with Branch Retinal Artery Occlusion

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR, 2BitterDB
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Compounds related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

(show all 44)
idCompoundScoreTop Affiliating Genes
1warfarin44 49 11 2413.5SERPINC1
2fluorescein44 1111.3SERPINC1
3inogatran4410.0SERPINC1, F5
4ecarin4410.0F5, SERPINC1
5hirugen4410.0F5, SERPINC1
6spectrozyme4410.0SERPINC1, F5
7danaparoid4410.0F5, SERPINC1
8nafamostat mesilate4410.0F5, SERPINC1
9eltrombopag49 1111.0F5, SERPINC1
10ancrod4410.0F5, SERPINC1
11ximelagatran44 1111.0F5, SERPINC1
12heparinoids4410.0SERPINC1, F5
13fondaparinux4410.0SERPINC1, F5
14bivalirudin44 1111.0F5, SERPINC1
15argatroban44 1111.0F5, SERPINC1
16desogestrel44 1111.0F5, SERPINC1
17protamine sulfate4410.0F5, SERPINC1
18gestodene44 1111.0SERPINC1, F5
19benzamidine44 1110.9F5, SERPINC1
20ristocetin449.9F5, SERPINC1
21tibolone449.9SERPINC1, F5
22levonorgestrel44 59 28 1112.9SERPINC1, F5
235-methyltetrahydrofolate44 1110.9F5, MTHFR
24desmopressin44 59 28 1112.9SERPINC1, F5
25coumarin44 2 49 2412.9SERPINC1, F5
26cystathionine449.8MTHFR, F5
27ulinastatin449.8TNF, SERPINC1
28taurine chloramine449.8TNF, F5
29hirudin449.8F5, SERPINC1
30protamine449.7SERPINC1, F5
31dextran sulfate449.7F5
32dermatan sulfate449.7F5, SERPINC1
33vitamin b6449.7MTHFR, F5
34raloxifene44 28 49 1112.6F5, SERPINC1
35sulfasalazine44 28 49 1112.6TNF, MTHFR
36homocysteine44 2410.5F5, MTHFR, SERPINC1
37folate449.4F5, MTHFR, SERPINC1
38gabexate mesilate449.4SERPINC1, F5, TNF
39aspirin44 49 28 2412.4SERPINC1, MTHFR, F5
40ascorbic acid44 2410.4F5, MTHFR, SERPINC1
41glucosamine44 11 2411.3SERPINC1, TNF
42carbamazepine44 49 1111.3MTHFR, TNF
43prostacyclin449.3SERPINC1, F5, TNF
44fibrinogen448.9TNF, F5, MTHFR, SERPINC1

GO Terms for genes affiliated with Branch Retinal Artery Occlusion

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16Gene Ontology
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Biological processes related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood circulationGO:0080159.5MTHFR, F5

Molecular functions related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.4SERPINC1, TNF

Products for genes affiliated with Branch Retinal Artery Occlusion

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  • Antibodies
  • Proteins
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  • Antibodies

Sources for Branch Retinal Artery Occlusion

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet