MCID: BRN026
MIFTS: 43

Branch Retinal Artery Occlusion malady

Cardiovascular diseases category

Summaries for Branch Retinal Artery Occlusion

About this section
Sources:
66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Wikipedia:66 Branch retinal artery occlusion (BRAO) is a rare retinal vascular disorder in which one of the branches... more...

MalaCards: Branch Retinal Artery Occlusion, also known as retinal arterial branch occlusion, is related to retinal vein occlusion and central retinal vein occlusion. An important gene associated with Branch Retinal Artery Occlusion is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1), and among its related pathways are Collagen biosynthesis and modifying enzymes and Complement and coagulation cascades. The compounds inogatran and ecarin have been mentioned in the context of this disorder. Affiliated tissues include eye, thyroid and retina, and related mouse phenotypes are liver/biliary system and nervous system.

Aliases & Classifications for Branch Retinal Artery Occlusion

About this section
Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH, 28ICD9CM
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

branch retinal artery occlusion 9 11 63
retinal arterial branch occlusion 9
arterial retinal branch occlusion 9


External Ids:

Disease Ontology9 DOID:13094
NCIt41 C34436
SNOMED-CT59 50821009
MeSH36 D015356
ICD9CM28 362.32

Related Diseases for Branch Retinal Artery Occlusion

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Graphical network of the top 20 diseases related to Branch Retinal Artery Occlusion:



Diseases related to branch retinal artery occlusion

Symptoms for Branch Retinal Artery Occlusion

About this section

Drugs & Therapeutics for Branch Retinal Artery Occlusion

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Branch Retinal Artery Occlusion

Drug clinical trials:

Search ClinicalTrials for Branch Retinal Artery Occlusion

Search NIH Clinical Center for Branch Retinal Artery Occlusion

Search CenterWatch for Branch Retinal Artery Occlusion

Genetic Tests for Branch Retinal Artery Occlusion

About this section

Anatomical Context for Branch Retinal Artery Occlusion

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Branch Retinal Artery Occlusion:

34
Eye, Thyroid, Retina

Animal Models for Branch Retinal Artery Occlusion or affiliated genes

About this section
Sources:
38MGI
See all sources

MGI Mouse Phenotypes related to Branch Retinal Artery Occlusion:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7F5, SERPINC1, TNF
2MP:00036317.8F5, MTHFR, SERPINC1, TNF

Publications for Branch Retinal Artery Occlusion

About this section
Sources:
53PubMed
See all sources

Articles related to Branch Retinal Artery Occlusion:

(show top 50)    (show all 122)
idTitleAuthorsYear
1
Simultaneous vitreous hemorrhage and branch retinal artery occlusion after prepapillary arterial loop rupture. (23410854)
2013
2
Neuroretinitis with branch retinal artery occlusion in a 15-year-old female. (24348414)
2013
3
Acute and chronic spectral domain optical coherence tomography features of branch retinal artery occlusion. (23661655)
2013
4
Branch retinal artery occlusion in a patient with patent foramen ovale. (23825714)
2013
5
A Case of Branch Retinal Artery Occlusion following Uneventful Phacoemulsification. (23626570)
2013
6
Unilateral branch retinal arterial occlusion following administration of bevacizumab for branch retinal vein occlusion. (23179231)
2013
7
Branch retinal artery occlusion caused by toxoplasmosis in an adolescent. (23139678)
2012
8
Branch retinal artery occlusion secondary to antiphospholipid syndrome. (23281524)
2012
9
A branch retinal artery occlusion in a patient with Gaucher disease. (21805401)
2012
10
The final retinal thickness in eyes with branch retinal artery occlusion. (22740109)
2012
11
Recurrent bilateral branch retinal artery occlusion with hearing loss and encephalopathy: the first case report of Susac syndrome in Korea. (22065912)
2011
12
Transcorneal electrical stimulation improves visual function in eyes with branch retinal artery occlusion. (21499563)
2011
13
Optic disc macroaneurysm in evolution: from incidental finding to branch retinal artery occlusion and spontaneous resolution. (21427799)
2011
14
Branch retinal artery occlusion after septoplasty. (22785539)
2010
15
Branch retinal artery occlusion after septoplasty. (21117572)
2010
16
Two cases of branch retinal arterial occlusion after carotid artery stenting in the carotid stenosis. (19337482)
2009
17
Restoration of retinal blood flow via translumenal Nd:YAG embolysis/embolectomy (TYL/E) for central and branch retinal artery occlusion. (18301027)
2008
18
Restoration of retinal blood flow via translumenal Nd:YAG embolysis/embolectomy (TYL/E) for central and branch retinal artery occlusion. (19430398)
2008
19
Longitudinal analysis of retinal changes after branch retinal artery occlusion using optical coherence tomography. (18215797)
2008
20
Branch retinal artery occlusion: visual prognosis. (18599018)
2008
21
Recovery of retinal sensitivity after transient branch retinal artery occlusion. (17674925)
2007
22
Branch retinal artery occlusion associated with compound heterozygous genotype for methylenetetrahydrofolate reductase. (17357807)
2007
23
A case of branch retinal artery occlusion associated with presumed optic neuritis. (16897231)
2006
24
Branch retinal artery occlusion during coronary angiography. (16272234)
2005
25
Branch retinal artery occlusion in a young man with hyperhomocysteinemia. (16205577)
2005
26
Is there really a correlation between transluminal Nd:YAG laser embolysis procedure for branch retinal artery occlusion and reperfusion as well as visual restoration? (12824854)
2003
27
Translumenal Nd:YAG laser embolysis for branch retinal artery occlusion. (11927856)
2002
28
Primary antiphospholipid syndrome presenting with a branch retinal artery occlusion in a 15-year-old boy. (12150590)
2002
29
Bilateral prepapillary loops with unilateral branch retinal artery occlusion following thrombus at the loop apex. (11217933)
2001
30
Multifocal electroretinograms in patients with branch retinal artery occlusion. (11133882)
2001
31
Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease. (12201349)
2001
32
Branch retinal artery occlusion; another complication of sildenafil. (10979658)
2000
33
Collaterals in branch retinal artery occlusion. (10219042)
1999
34
Branch retinal artery occlusion: angiographic demonstration of increased retinal blood flow after external carotid endarterectomy. (10088062)
1999
35
Branch retinal artery occlusion in systemic diseases: a case report. (10355155)
1999
36
Internal carotid artery dissection causing a branch retinal artery occlusion in a young adult. (9625559)
1998
37
Delayed branch retinal artery occlusion following presumed blunt common carotid dissection. (9715701)
1998
38
Branch retinal artery occlusion by diathermy of a persistent hyaloid artery. (9439377)
1997
39
Branch retinal artery occlusion in a child. (8913134)
1996
40
Branch retinal artery occlusion caused by a mitral valve papillary fibroelastoma. (7872394)
1995
41
Bilateral optic neuritis with branch retinal artery occlusion associated with vaccination. (7835178)
1994
42
Branch retinal artery occlusion in pregnancy. (8297878)
1994
43
Branch retinal artery occlusion following thyroidectomy for papillary carcinoma of the thyroid: report of a case. (8400682)
1993
44
Branch retinal artery occlusion associated with Lyme disease. (1929948)
1991
45
Branch retinal artery occlusion after platelet transfusion. (2297022)
1990
46
Branch retinal artery occlusion secondary to percutaneous transluminal coronary angioplasty. (2523726)
1989
47
Retinitis pigmentosa and branch retinal artery occlusion with anticardiolipin antibody. Case report. (2923554)
1989
48
Branch retinal-artery occlusion in acquired immunodeficiency syndrome prodrome. (3408084)
1988
49
Disappearance of myelinated retinal nerve fibers after a branch retinal artery occlusion. (3591888)
1987
50
Branch retinal artery occlusion in patients with Hodgkin's disease. (6703578)
1984

Variations for Branch Retinal Artery Occlusion

About this section

Expression for genes affiliated with Branch Retinal Artery Occlusion

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Branch Retinal Artery Occlusion

Search GEO for disease gene expression data for Branch Retinal Artery Occlusion.

Pathways for genes affiliated with Branch Retinal Artery Occlusion

About this section
Sources:
51PathCards, 56Reactome, 54QIAGEN, 31KEGG, 39NCBI BioSystems Database, 55R&D Systems
See all sources

Pathways related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5F5, SERPINC1
2
Show member pathways
Complement Activation, Classical Pathway39
Complement and Coagulation Cascades39
9.5F5, SERPINC1
3
Show member pathways
9.5F5, SERPINC1
4
Show member pathways
thioredoxin pathway39
9.0MTHFR, TNF

Compounds for genes affiliated with Branch Retinal Artery Occlusion

About this section
Sources:
46Novoseek, 12DrugBank, 52PharmGKB, 62Tocris Bioscience, 30IUPHAR, 3BitterDB, 25HMDB
See all sources

Compounds related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

(show top 50)    (show all 70)
idCompoundScoreTop Affiliating Genes
1inogatran469.9F5, SERPINC1
2ecarin469.9SERPINC1, F5
3hirugen469.9SERPINC1, F5
4spectrozyme469.9SERPINC1, F5
5nafamostat mesilate469.9F5, SERPINC1
6danaparoid469.9F5, SERPINC1
7ximelagatran46 1210.9SERPINC1, F5
8ancrod469.9SERPINC1, F5
9heparinoids469.9F5, SERPINC1
10fondaparinux469.9F5, SERPINC1
11bivalirudin46 1210.9SERPINC1, F5
12argatroban46 1210.9F5, SERPINC1
13desogestrel46 1210.9F5, SERPINC1
14protamine sulfate469.9F5, SERPINC1
15gestodene46 1210.9SERPINC1, F5
16eltrombopag52 1210.9F5, SERPINC1
17benzamidine46 1210.8F5, SERPINC1
18ristocetin469.8F5, SERPINC1
19tibolone469.8F5, SERPINC1
20levonorgestrel46 62 30 1212.8SERPINC1, F5
21coumarin46 3 52 2512.8F5, SERPINC1
22desmopressin46 62 30 1212.8F5, SERPINC1
23fluorescein46 1210.8F5, SERPINC1
24hirudin469.8F5, SERPINC1
255-methyltetrahydrofolate46 1210.7MTHFR, F5
26protamine469.7SERPINC1, F5
27cystathionine469.7F5, MTHFR
28raloxifene46 52 30 1212.6SERPINC1, F5
29vitamin b6469.6F5, MTHFR
30dermatan sulfate469.6SERPINC1, F5
31ulinastatin469.6SERPINC1, TNF
32taurine chloramine469.5F5, TNF
33dextran sulfate469.5F5, SERPINC1
34sulfasalazine30 46 52 1212.3TNF, MTHFR
35vitamin b12469.3F5, MTHFR
36warfarin46 52 25 1212.3SERPINC1, MTHFR, F5
37homocysteine46 2510.3F5, MTHFR, SERPINC1
38mycophenolate mofetil46 52 1211.3F5, TNF
39folate469.3SERPINC1, MTHFR, F5
40glucosamine46 25 1211.3SERPINC1, TNF
41aspirin46 52 30 2512.3SERPINC1, MTHFR, F5
42ascorbic acid46 2510.2SERPINC1, MTHFR, F5
43kininogen469.2F5, SERPINC1
44gabexate mesilate469.1F5, SERPINC1, TNF
45creatinine469.1F5, MTHFR, SERPINC1
46prostacyclin469.1F5, SERPINC1, TNF
47heparin46 30 25 1212.1F5, MTHFR, SERPINC1
48carbamazepine46 52 1210.9TNF, MTHFR
49fibrinogen468.5F5, MTHFR, SERPINC1, TNF
50serine468.3TNF, SERPINC1, MTHFR, F5

GO Terms for genes affiliated with Branch Retinal Artery Occlusion

About this section
Sources:
17Gene Ontology
See all sources

Cellular components related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.7F5, SERPINC1, TNF

Biological processes related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood circulationGO:0080159.0F5, MTHFR
2response to hypoxiaGO:0016669.0MTHFR, TNF

Molecular functions related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.2SERPINC1, TNF

Products for genes affiliated with Branch Retinal Artery Occlusion

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Branch Retinal Artery Occlusion

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet