MCID: BRN026
MIFTS: 43

Branch Retinal Artery Occlusion malady

Cardiovascular diseases category
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Summaries for Branch Retinal Artery Occlusion

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 Branch retinal artery occlusion (BRAO) is a rare retinal vascular disorder in which one of the branches... more...

MalaCards: Branch Retinal Artery Occlusion, also known as retinal arterial branch occlusion, is related to retinal vein occlusion and central retinal vein occlusion. An important gene associated with Branch Retinal Artery Occlusion is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1), and among its related pathways are Collagen biosynthesis and modifying enzymes and Complement and coagulation cascades. The compounds inogatran and ecarin have been mentioned in the context of this disorder. Affiliated tissues include eye, thyroid and retina, and related mouse phenotypes are liver/biliary system and nervous system.

Aliases & Classifications for Branch Retinal Artery Occlusion

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8Disease Ontology, 10DISEASES, 62UMLS, 40NCIt, 58SNOMED-CT, 35MeSH, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

branch retinal artery occlusion 8 10 62
retinal arterial branch occlusion 8
arterial retinal branch occlusion 8


External Ids:

Disease Ontology8 DOID:13094
NCIt40 C34436
SNOMED-CT58 50821009
MeSH35 D015356
ICD9CM27 362.32

Related Diseases for Branch Retinal Artery Occlusion

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Branch Retinal Artery Occlusion:



Diseases related to branch retinal artery occlusion

Symptoms for Branch Retinal Artery Occlusion

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Drugs & Therapeutics for Branch Retinal Artery Occlusion

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Branch Retinal Artery Occlusion

Genetic Tests for Branch Retinal Artery Occlusion

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Anatomical Context for Branch Retinal Artery Occlusion

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33MalaCards
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MalaCards organs/tissues related to Branch Retinal Artery Occlusion:

33
Eye, Thyroid, Retina

Animal Models for Branch Retinal Artery Occlusion or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Branch Retinal Artery Occlusion:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7F5, SERPINC1, TNF
2MP:00036317.8F5, MTHFR, SERPINC1, TNF

Publications for Branch Retinal Artery Occlusion

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52PubMed
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Articles related to Branch Retinal Artery Occlusion:

(show top 50)    (show all 122)
idTitleAuthorsYear
1
Simultaneous vitreous hemorrhage and branch retinal artery occlusion after prepapillary arterial loop rupture. (23410854)
2013
2
Neuroretinitis with branch retinal artery occlusion in a 15-year-old female. (24348414)
2013
3
Acute and chronic spectral domain optical coherence tomography features of branch retinal artery occlusion. (23661655)
2013
4
Branch retinal artery occlusion in a patient with patent foramen ovale. (23825714)
2013
5
A Case of Branch Retinal Artery Occlusion following Uneventful Phacoemulsification. (23626570)
2013
6
Unilateral branch retinal arterial occlusion following administration of bevacizumab for branch retinal vein occlusion. (23179231)
2013
7
Branch retinal artery occlusion caused by toxoplasmosis in an adolescent. (23139678)
2012
8
Branch retinal artery occlusion secondary to antiphospholipid syndrome. (23281524)
2012
9
A branch retinal artery occlusion in a patient with Gaucher disease. (21805401)
2012
10
The final retinal thickness in eyes with branch retinal artery occlusion. (22740109)
2012
11
Recurrent bilateral branch retinal artery occlusion with hearing loss and encephalopathy: the first case report of Susac syndrome in Korea. (22065912)
2011
12
Transcorneal electrical stimulation improves visual function in eyes with branch retinal artery occlusion. (21499563)
2011
13
Optic disc macroaneurysm in evolution: from incidental finding to branch retinal artery occlusion and spontaneous resolution. (21427799)
2011
14
Branch retinal artery occlusion after septoplasty. (22785539)
2010
15
Branch retinal artery occlusion after septoplasty. (21117572)
2010
16
Two cases of branch retinal arterial occlusion after carotid artery stenting in the carotid stenosis. (19337482)
2009
17
Restoration of retinal blood flow via translumenal Nd:YAG embolysis/embolectomy (TYL/E) for central and branch retinal artery occlusion. (18301027)
2008
18
Restoration of retinal blood flow via translumenal Nd:YAG embolysis/embolectomy (TYL/E) for central and branch retinal artery occlusion. (19430398)
2008
19
Longitudinal analysis of retinal changes after branch retinal artery occlusion using optical coherence tomography. (18215797)
2008
20
Branch retinal artery occlusion: visual prognosis. (18599018)
2008
21
Recovery of retinal sensitivity after transient branch retinal artery occlusion. (17674925)
2007
22
Branch retinal artery occlusion associated with compound heterozygous genotype for methylenetetrahydrofolate reductase. (17357807)
2007
23
A case of branch retinal artery occlusion associated with presumed optic neuritis. (16897231)
2006
24
Branch retinal artery occlusion during coronary angiography. (16272234)
2005
25
Branch retinal artery occlusion in a young man with hyperhomocysteinemia. (16205577)
2005
26
Is there really a correlation between transluminal Nd:YAG laser embolysis procedure for branch retinal artery occlusion and reperfusion as well as visual restoration? (12824854)
2003
27
Translumenal Nd:YAG laser embolysis for branch retinal artery occlusion. (11927856)
2002
28
Primary antiphospholipid syndrome presenting with a branch retinal artery occlusion in a 15-year-old boy. (12150590)
2002
29
Bilateral prepapillary loops with unilateral branch retinal artery occlusion following thrombus at the loop apex. (11217933)
2001
30
Multifocal electroretinograms in patients with branch retinal artery occlusion. (11133882)
2001
31
Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease. (12201349)
2001
32
Branch retinal artery occlusion; another complication of sildenafil. (10979658)
2000
33
Collaterals in branch retinal artery occlusion. (10219042)
1999
34
Branch retinal artery occlusion: angiographic demonstration of increased retinal blood flow after external carotid endarterectomy. (10088062)
1999
35
Branch retinal artery occlusion in systemic diseases: a case report. (10355155)
1999
36
Internal carotid artery dissection causing a branch retinal artery occlusion in a young adult. (9625559)
1998
37
Delayed branch retinal artery occlusion following presumed blunt common carotid dissection. (9715701)
1998
38
Branch retinal artery occlusion by diathermy of a persistent hyaloid artery. (9439377)
1997
39
Branch retinal artery occlusion in a child. (8913134)
1996
40
Branch retinal artery occlusion caused by a mitral valve papillary fibroelastoma. (7872394)
1995
41
Bilateral optic neuritis with branch retinal artery occlusion associated with vaccination. (7835178)
1994
42
Branch retinal artery occlusion in pregnancy. (8297878)
1994
43
Branch retinal artery occlusion following thyroidectomy for papillary carcinoma of the thyroid: report of a case. (8400682)
1993
44
Branch retinal artery occlusion associated with Lyme disease. (1929948)
1991
45
Branch retinal artery occlusion after platelet transfusion. (2297022)
1990
46
Branch retinal artery occlusion secondary to percutaneous transluminal coronary angioplasty. (2523726)
1989
47
Retinitis pigmentosa and branch retinal artery occlusion with anticardiolipin antibody. Case report. (2923554)
1989
48
Branch retinal-artery occlusion in acquired immunodeficiency syndrome prodrome. (3408084)
1988
49
Disappearance of myelinated retinal nerve fibers after a branch retinal artery occlusion. (3591888)
1987
50
Branch retinal artery occlusion in patients with Hodgkin's disease. (6703578)
1984

Variations for Branch Retinal Artery Occlusion

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Expression for genes affiliated with Branch Retinal Artery Occlusion

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Branch Retinal Artery Occlusion

Search GEO for disease gene expression data for Branch Retinal Artery Occlusion.

Pathways for genes affiliated with Branch Retinal Artery Occlusion

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50PathCards, 55Reactome, 53QIAGEN, 30KEGG, 38NCBI BioSystems Database, 54R&D Systems
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Pathways related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5F5, SERPINC1
2
Show member pathways
Complement Activation, Classical Pathway38
Complement and Coagulation Cascades38
9.5F5, SERPINC1
3
Show member pathways
9.5F5, SERPINC1
4
Show member pathways
thioredoxin pathway38
9.0MTHFR, TNF

Compounds for genes affiliated with Branch Retinal Artery Occlusion

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Sources:
45Novoseek, 11DrugBank, 51PharmGKB, 61Tocris Bioscience, 29IUPHAR, 3BitterDB, 24HMDB
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Compounds related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

(show top 50)    (show all 70)
idCompoundScoreTop Affiliating Genes
1inogatran459.9F5, SERPINC1
2ecarin459.9SERPINC1, F5
3hirugen459.9SERPINC1, F5
4spectrozyme459.9SERPINC1, F5
5nafamostat mesilate459.9F5, SERPINC1
6danaparoid459.9F5, SERPINC1
7ximelagatran45 1110.9SERPINC1, F5
8ancrod459.9SERPINC1, F5
9heparinoids459.9F5, SERPINC1
10fondaparinux459.9F5, SERPINC1
11bivalirudin45 1110.9SERPINC1, F5
12argatroban45 1110.9F5, SERPINC1
13desogestrel45 1110.9F5, SERPINC1
14protamine sulfate459.9F5, SERPINC1
15gestodene45 1110.9SERPINC1, F5
16eltrombopag51 1110.9F5, SERPINC1
17benzamidine45 1110.8F5, SERPINC1
18ristocetin459.8F5, SERPINC1
19tibolone459.8F5, SERPINC1
20levonorgestrel45 61 29 1112.8SERPINC1, F5
21coumarin45 3 51 2412.8F5, SERPINC1
22desmopressin45 61 29 1112.8F5, SERPINC1
23fluorescein45 1110.8F5, SERPINC1
24hirudin459.8F5, SERPINC1
255-methyltetrahydrofolate45 1110.7MTHFR, F5
26protamine459.7SERPINC1, F5
27cystathionine459.7F5, MTHFR
28raloxifene45 51 29 1112.6SERPINC1, F5
29vitamin b6459.6F5, MTHFR
30dermatan sulfate459.6SERPINC1, F5
31ulinastatin459.6SERPINC1, TNF
32taurine chloramine459.5F5, TNF
33dextran sulfate459.5F5, SERPINC1
34sulfasalazine29 45 51 1112.3TNF, MTHFR
35vitamin b12459.3F5, MTHFR
36warfarin45 51 24 1112.3SERPINC1, MTHFR, F5
37homocysteine45 2410.3F5, MTHFR, SERPINC1
38mycophenolate mofetil45 51 1111.3F5, TNF
39folate459.3SERPINC1, MTHFR, F5
40glucosamine45 24 1111.3SERPINC1, TNF
41aspirin45 51 29 2412.3SERPINC1, MTHFR, F5
42ascorbic acid45 2410.2SERPINC1, MTHFR, F5
43kininogen459.2F5, SERPINC1
44gabexate mesilate459.1F5, SERPINC1, TNF
45creatinine459.1F5, MTHFR, SERPINC1
46prostacyclin459.1F5, SERPINC1, TNF
47heparin45 29 24 1112.1F5, MTHFR, SERPINC1
48carbamazepine45 51 1110.9TNF, MTHFR
49fibrinogen458.5F5, MTHFR, SERPINC1, TNF
50serine458.3TNF, SERPINC1, MTHFR, F5

GO Terms for genes affiliated with Branch Retinal Artery Occlusion

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16Gene Ontology
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Cellular components related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.7F5, SERPINC1, TNF

Biological processes related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood circulationGO:0080159.0F5, MTHFR
2response to hypoxiaGO:0016669.0MTHFR, TNF

Molecular functions related to Branch Retinal Artery Occlusion according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.2SERPINC1, TNF

Products for genes affiliated with Branch Retinal Artery Occlusion

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  • Antibodies
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Sources for Branch Retinal Artery Occlusion

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet