MCID: BRC054
MIFTS: 11

Brca1 Hereditary Breast and Ovarian Cancer malady

Genetic diseases, Rare diseases, Cancer diseases categories

Summaries for Brca1 Hereditary Breast and Ovarian Cancer

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NIH Rare Diseases:41 Brca1 hereditary breast and ovarian cancer syndrome (brca1 hboc) is an inherited condition that is characterized by an increased risk for a variety of different cancers. women with this condition have a 57-60% risk of developing breast cancer, a 40-59% risk of developing ovarian cancer and an 83% risk of developing contralateral breast cancer by age 70. men have a 1% lifetime risk of breast cancer and an increased risk for prostate cancer. brca1 hboc may also be associated with an elevated risk for cancers of the cervix, uterus, pancreas, esophagus, stomach, fallopian tube, and primary peritoneum; however, these risks are not well defined. this condition is caused by changes (mutations) in the brca1 gene and is inherited in an autosomal dominant manner. management may include high risk cancer screening, chemoprevention and/or prophylactic surgeries. last updated: 3/10/2015

MalaCards based summary: Brca1 Hereditary Breast and Ovarian Cancer, is also known as ovarian cancer, familial, susceptibility to, 1, included An important gene associated with Brca1 Hereditary Breast and Ovarian Cancer is BRCA1 (breast cancer 1, early onset). Affiliated tissues include breast, pancreas and uterus.

Aliases & Classifications for Brca1 Hereditary Breast and Ovarian Cancer

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Brca1 Hereditary Breast and Ovarian Cancer, Aliases & Descriptions:

Name: Brca1 Hereditary Breast and Ovarian Cancer 41 20
Ovarian Cancer, Familial, Susceptibility to, 1, Included 41
Breast Cancer, Familial, Susceptibility to, 1, Included 41
 
Breast Cancer, Familial 1; 41
Brovca1 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases, Cancer diseases


Related Diseases for Brca1 Hereditary Breast and Ovarian Cancer

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Symptoms for Brca1 Hereditary Breast and Ovarian Cancer

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Drugs & Therapeutics for Brca1 Hereditary Breast and Ovarian Cancer

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Drug clinical trials:

Search ClinicalTrials for Brca1 Hereditary Breast and Ovarian Cancer

Search NIH Clinical Center for Brca1 Hereditary Breast and Ovarian Cancer

Genetic Tests for Brca1 Hereditary Breast and Ovarian Cancer

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Genetic tests related to Brca1 Hereditary Breast and Ovarian Cancer:

id Genetic test Affiliating Genes
1 Brca1 Hereditary Breast and Ovarian Cancer20 BRCA1

Anatomical Context for Brca1 Hereditary Breast and Ovarian Cancer

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MalaCards organs/tissues related to Brca1 Hereditary Breast and Ovarian Cancer:

31
Breast, Pancreas, Uterus, Prostate, Cervix

Animal Models for Brca1 Hereditary Breast and Ovarian Cancer or affiliated genes

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Publications for Brca1 Hereditary Breast and Ovarian Cancer

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Variations for Brca1 Hereditary Breast and Ovarian Cancer

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Expression for genes affiliated with Brca1 Hereditary Breast and Ovarian Cancer

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Search GEO for disease gene expression data for Brca1 Hereditary Breast and Ovarian Cancer.

Pathways for genes affiliated with Brca1 Hereditary Breast and Ovarian Cancer

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Compounds for genes affiliated with Brca1 Hereditary Breast and Ovarian Cancer

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GO Terms for genes affiliated with Brca1 Hereditary Breast and Ovarian Cancer

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Products for genes affiliated with Brca1 Hereditary Breast and Ovarian Cancer

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Brca1 Hereditary Breast and Ovarian Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet