MCID: BRS045
MIFTS: 25

Breast Adenoma malady

Cancer diseases category
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Summaries for Breast Adenoma

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Sources:
33MalaCards
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MalaCards: Breast Adenoma, also known as ademoma - breast, is related to adenoma and sertoli-leydig cell tumor. An important gene associated with Breast Adenoma is TP53 (tumor protein p53), and among its related pathways are ErbB4 Pathway and fMLP Pathway. The compounds radicicol and vinblastine have been mentioned in the context of this disorder. Affiliated tissues include breast and skin.

Aliases & Classifications for Breast Adenoma

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Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

breast adenoma 8 10 62
ademoma - breast 8


External Ids:

Disease Ontology8 DOID:1625
SNOMED-CT58 269640007
NCIt40 C40382

Related Diseases for Breast Adenoma

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Breast Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1adenoma10.3
2sertoli-leydig cell tumor10.0
3leydig cell tumor10.0
4papilloma10.0
5skin papilloma10.0
6lung cancer10.0DNAH8, TP53
7gastritis10.0DNAH8, TP53
8rhabdomyosarcoma9.9DNAH8, TP53

Graphical network of diseases related to Breast Adenoma:



Diseases related to breast adenoma

Symptoms for Breast Adenoma

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Drugs & Therapeutics for Breast Adenoma

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Breast Adenoma

Search NIH Clinical Center for Breast Adenoma

Genetic Tests for Breast Adenoma

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Anatomical Context for Breast Adenoma

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Sources:
33MalaCards
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MalaCards organs/tissues related to Breast Adenoma:

33
Breast, Skin

Animal Models for Breast Adenoma or affiliated genes

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Publications for Breast Adenoma

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Sources:
52PubMed
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Articles related to Breast Adenoma:

idTitleAuthorsYear
1
Ectopic breast adenoma of the anal margin: an atypical presentation of anorectal pain. (23229560)
2013
2
Mutation of p53 in skin papilloma and tubular breast adenoma of albino mice. (16624193)
2006
3
Immunohistochemical analysis of the distribution of the human ATPase (hASNA-I) in normal tissues and its overexpression in breast adenomas and carcinomas. (9774623)
1998
4
Ollier's disease associated with ovarian Sertoli-Leydig cell tumor and breast adenoma. (2029079)
1991

Variations for Breast Adenoma

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Expression for genes affiliated with Breast Adenoma

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Breast Adenoma

Search GEO for disease gene expression data for Breast Adenoma.

Pathways for genes affiliated with Breast Adenoma

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Sources:
50PathCards, 53QIAGEN, 60Thomson Reuters, 30KEGG, 38NCBI BioSystems Database, 51PharmGKB
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Pathways related to Breast Adenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1PAK4, TP53
2
Show member pathways
9.1PAK4, TP53
39.1PAK4, TP53
4
Show member pathways
ErbB receptor signaling network38
ErbB signaling pathway38
9.1PAK4, TP53

Compounds for genes affiliated with Breast Adenoma

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Sources:
45Novoseek, 61Tocris Bioscience, 11DrugBank, 51PharmGKB, 29IUPHAR, 24HMDB
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Compounds related to Breast Adenoma according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1radicicol45 61 1111.6TP53, DNAH8
2vinblastine45 51 1111.6TP53, DNAH8
3geldanamycin45 51 61 1112.6TP53, DNAH8
4antimonite459.6ASNA1, DNAH8
5curcumin459.5DNAH8, TP53
6phosphatidylserine45 29 1111.5TP53, DNAH8
7etoposide45 51 61 1112.4TP53, DNAH8
8doxorubicin45 51 1111.4TP53, DNAH8
9butyrate459.3TP53, DNAH8
10tamoxifen45 51 29 1112.1TP53, DNAH8
11arsenite45 2410.0DNAH8, TP53, ASNA1

GO Terms for genes affiliated with Breast Adenoma

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Sources:
16Gene Ontology
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Biological processes related to Breast Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell proliferationGO:0082839.1PAK4, TP53

Molecular functions related to Breast Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ATPase activityGO:0168879.3DNAH8, ASNA1
2ATP bindingGO:0055247.7DNAH8, ASNA1, PAK4, TP53

Products for genes affiliated with Breast Adenoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Breast Adenoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet