MCID: BRS045
MIFTS: 27

Breast Adenoma malady

Summaries for Breast Adenoma

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33MalaCards
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MalaCards: Breast Adenoma, also known as ademoma - breast, is related to adenoma and sertoli-leydig cell tumor. An important gene associated with Breast Adenoma is TP53 (tumor protein p53), and among its related pathways is ErbB signaling pathway. The compounds radicicol and antimonite have been mentioned in the context of this disorder. Affiliated tissues include thyroid, breast and skin.

Aliases & Classifications for Breast Adenoma

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 40NCIt
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Aliases & Descriptions:

breast adenoma 8 10 61
ademoma - breast 8


External Ids:

Disease Ontology8 DOID:1625
SNOMED-CT57 269640007
NCIt40 C40382

Related Diseases for Breast Adenoma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Breast Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma30.4TP53, DNAH8
2sertoli-leydig cell tumor10.0
3sertoli cell tumor10.0
4ollier disease10.0
5ovarian cancer10.0TP53
6kidney cancer10.0TP53
7gastroesophageal reflux disease10.0DNAH8
8bloom syndrome10.0DNAH8
9wilson disease10.0DNAH8
10gallbladder cancer10.0TP53
11werner syndrome10.0DNAH8

Graphical network of diseases related to Breast Adenoma:



Diseases related to breast adenoma

Clinical Features for Breast Adenoma

Drugs & Therapeutics for Breast Adenoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Breast Adenoma

Drug clinical trials:

Search ClinicalTrials for Breast Adenoma

Search NIH Clinical Center for Breast Adenoma

Search CenterWatch for Breast Adenoma

Genetic Tests for Breast Adenoma

Anatomical Context for Breast Adenoma

Sources:
33MalaCards
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MalaCards organs/tissues related to Breast Adenoma:

33
Thyroid, Breast, Skin, T cells, Pituitary

Animal Models for Breast Adenoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Breast Adenoma

Sources:
51PubMed
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Articles related to Breast Adenoma:

(show all 48)
idTitleAuthorsYear
1
Pituitary metastasis of an unknown neuroendocrine breast carcinoma mimicking a pituitary adenoma. (23635818)
2013
2
Ectopic breast adenoma of the anal margin: an atypical presentation of anorectal pain. (23229560)
2013
3
Adenomatous polyposis coli-mediated accumulation of abasic DNA lesions lead to cigarette smoke condensate-induced neoplastic transformation of normal breast epithelial cells. (23555190)
2013
4
Basal cell adenoma of the breast. (24082418)
2013
5
Ductal carcinoma inA situ arising in tubular adenoma of the breast. (22700460)
2012
6
A rare case of giant papillary adenoma of the breast. (22525553)
2012
7
Breast radiation correlates with side of parathyroid adenoma. (22207495)
2012
8
Malignant change in a massive pleomorphic adenoma resembling the presentation of advanced inflammatory breast cancer. (22464757)
2012
9
Pleomorphic adenoma of the breast initially misdiagnosed as metaplastic carcinoma in preoperative stereotactic biopsy: a case report and review of the literature. (21941969)
2011
10
Metastatic breast carcinoma to parathyroid adenoma on fine needle cytology sample: report of a case. (21837656)
2011
11
Ki-67 and Bcl-2 antigen expression in adenomatous colorectal polyps from women with breast cancer. (20177797)
2010
12
Intraductal fibroadenoma and intraductal phyllodes tumour--a part of the spectrum of the breast ductal adenoma? (20013344)
2010
13
A case of Peutz-Jeghers syndrome with breast cancer, bilateral sex cord tumor with annular tubules, and adenoma malignum caused by STK11 gene mutation. (19955943)
2009
14
Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype. (18841156)
2008
15
Tumour-to-tumour metastasis from a carcinoma of the breast to a pleomorphic adenoma of the parotid gland. (19128698)
2008
16
Apocrine adenoma of the breast. (18491794)
2008
17
Pleomorphic adenoma of the breast. (18770004)
2008
18
Ductal adenoma of the breast: immunohistochemistry of two cases. (19067857)
2008
19
Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells. (16924228)
2007
20
Pleomorphic adenoma of the breast should be excised with a cuff of normal tissue. (17593049)
2007
21
Methylation status and protein expression of adenomatous polyposis coli (APC) gene in breast cancer]. (17562262)
2007
22
Apocrine adenoma of the breast coexistent with invasive carcinoma. (17936522)
2007
23
Pleomorphic adenoma of the breast. (17214808)
2007
24
Naevus sebaceus on the female breast accompanied with a tubular apocrine adenoma and a syringocystadenoma papilliferum. (17535243)
2007
25
Mutation of p53 in skin papilloma and tubular breast adenoma of albino mice. (16624193)
2006
26
7,12-Dimethylbenzanthracene-dependent transcriptional regulation of adenomatous polyposis coli (APC) gene expression in normal breast epithelial cells is mediated by GC-box binding protein Sp3. (16150893)
2006
27
Pleomorphic adenoma (benign mixed tumor) of the breast: a case report and review of the literature. (15991841)
2005
28
Pleomorphic adenoma of the breast: case report and review of the literature. (16299746)
2005
29
Pleomorphic adenoma of the breast. (16297122)
2005
30
Pleomorphic adenoma of the parotid and breast in a male patient. (16175906)
2005
31
Breast carcinoma metastatic to follicular adenoma of the thyroid gland. (15842643)
2005
32
Primary hyperparathyroidism associatiated with aldosterone-producing adrenocortical adenoma and breast cancer: relation to MEN1 gene. (15168774)
2004
33
MUC1 can interact with adenomatous polyposis coli in breast cancer. (15020226)
2004
34
Parathyroid adenoma-related hypercalcaemia in breast cancer: a critical diagnosis in clinical oncology. (14627187)
2003
35
Adenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancers. (11437404)
2001
36
Comments on: Involvement of adenomatous polyposis coli (APC) beta-catenin signalling in human breast cancer, JAPhnsson M, Borg A, Nilbert M, Andersson, T. Eur.J. Cancer 2000, 36, 242-248. (11327050)
2001
37
Apocrine adenoma of the breast: diagnosis on large core needle biopsy. (11358045)
2001
38
Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer. (10741284)
2000
39
Immunohistochemical analysis of the distribution of the human ATPase (hASNA-I) in normal tissues and its overexpression in breast adenomas and carcinomas. (9774623)
1998
40
Erosive adenomatosis of the nipple: a benign imitator of malignant breast disease. (9040979)
1997
41
Pituitary adenoma and bilateral male breast cancer: an unusual association. (9040805)
1997
42
Ductal adenoma of the breast and the Carney complex. (8764753)
1996
43
Optimization of a classical aromatase activity assay and application in normal, adenomatous and malignant breast parenchyma. (9010322)
1996
44
Absence of cyclin D1/PRAD1 point mutations in human breast cancers and parathyroid adenomas and identification of a new cyclin D1 gene polymorphism. (7621424)
1995
45
Tubular adenoma of the breast: an immunohistochemical study of ten cases. (8927570)
1995
46
Ollier's disease associated with ovarian Sertoli-Leydig cell tumor and breast adenoma. (2029079)
1991
47
Apocrine adenoma of the breast: report of a case with investigation of lectin binding patterns in apocrine breast lesions. (2362943)
1990
48
Apocrine adenoma of the breast. (3754126)
1986

Genetic Variations for Breast Adenoma

Expression for genes affiliated with Breast Adenoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Breast Adenoma

Search GEO for disease gene expression data for Breast Adenoma.

Pathways for genes affiliated with Breast Adenoma

Sources:
30KEGG, 38NCBI BioSystems Database
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Pathways related to Breast Adenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1TP53, PAK4

Compounds for genes affiliated with Breast Adenoma

Sources:
45Novoseek, 60Tocris Bioscience, 11DrugBank, 50PharmGKB, 29IUPHAR, 24HMDB
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Compounds related to Breast Adenoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1radicicol45 60 1111.5TP53, DNAH8
2antimonite459.5ASNA1, DNAH8
3vinblastine45 50 1111.4DNAH8, TP53
4phosphatidylserine45 29 1111.4TP53, DNAH8
5geldanamycin45 50 60 1112.3TP53, DNAH8
6curcumin459.1TP53, DNAH8
7arsenite45 249.9TP53, ASNA1, DNAH8

GO Terms for genes affiliated with Breast Adenoma

Sources:
16Gene Ontology
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Molecular functions related to Breast Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ATPase activityGO:0168879.3ASNA1, DNAH8
2ATP bindingGO:0055247.7TP53, ASNA1, PAK4, DNAH8

Products for genes affiliated with Breast Adenoma

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Sources for Breast Adenoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet