MCID: BRS026
MIFTS: 22

Breast Apocrine Carcinoma malady

Cancer diseases category

Summaries for Breast Apocrine Carcinoma

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MalaCards: Breast Apocrine Carcinoma, also known as apocrine breast carcinoma, is related to breast apocrine carcinoma in situ and endometrial carcinoma. An important gene associated with Breast Apocrine Carcinoma is TP53 (tumor protein p53). The compounds retinoic acid and estrogen have been mentioned in the context of this disorder. Affiliated tissues include breast.

Aliases & Classifications for Breast Apocrine Carcinoma

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8Disease Ontology, 60UMLS, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

breast apocrine carcinoma 8
apocrine breast carcinoma 60


External Ids:

Disease Ontology8 DOID:6581
NCIt39 C5141

Related Diseases for Breast Apocrine Carcinoma

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17GeneCards, 18GeneDecks
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Diseases in the Breast Apocrine Carcinoma family:

Breast Apocrine Carcinoma in Situ

Diseases related to Breast Apocrine Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1breast apocrine carcinoma in situ10.3
2endometrial carcinoma10.2
3psoriasis10.0S100A7
4basal cell carcinoma10.0S100A7, TP53
5ductal carcinoma in situ10.0S100A7, TP53
6bladder carcinoma10.0TP53, S100A7
7squamous cell carcinoma10.0S100A7, TP53
8breast cancer10.0S100A7, TP53

Graphical network of diseases related to Breast Apocrine Carcinoma:



Diseases related to breast apocrine carcinoma

Clinical Features for Breast Apocrine Carcinoma

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Drugs & Therapeutics for Breast Apocrine Carcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Breast Apocrine Carcinoma

Drug clinical trials:

Search ClinicalTrials for Breast Apocrine Carcinoma

Search NIH Clinical Center for Breast Apocrine Carcinoma

Search CenterWatch for Breast Apocrine Carcinoma

Genetic Tests for Breast Apocrine Carcinoma

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Anatomical Context for Breast Apocrine Carcinoma

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32MalaCards
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MalaCards organs/tissues related to Breast Apocrine Carcinoma:

32
Breast

Animal Models for Breast Apocrine Carcinoma or affiliated genes

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Publications for Breast Apocrine Carcinoma

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50PubMed
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Articles related to Breast Apocrine Carcinoma:

(show all 34)
idTitleAuthorsYear
1
Expression of 5I+-reductase in apocrine carcinoma of the breast and its correlation with clinicopathological aggressiveness. (22486281)
2012
2
Intracytoplasmic lipid accumulation in apocrine carcinoma of the breast evaluated with adipophilin immunoreactivity: a possible link between apocrine carcinoma and lipid-rich carcinoma. (21566511)
2011
3
Massive myoepithelial proliferation (myoepitheliosis) with lumpy deposits of basement membrane material closely associated with apocrine adenosis and ductal carcinoma in situ of the breast. (21951673)
2011
4
Incidental detection of breast apocrine carcinoma via endometrial cytology. (22041622)
2011
5
IMP3, a proposed novel basal phenotype marker, is commonly overexpressed in adenoid cystic carcinomas but not in apocrine carcinomas of the breast. (21436679)
2011
6
Encapsulated apocrine papillary carcinoma of the breast: case report with clinicopathologic and immunohistochemical study. (20734358)
2011
7
EGFR and HER-2/neu expression in invasive apocrine carcinoma of the breast. (20208479)
2010
8
Encapsulated apocrine papillary carcinoma of the breast--a tumour of uncertain malignant potential: report of five cases. (19862552)
2009
9
Oestrogen receptor-beta1 but not oestrogen receptor-betacx is of prognostic value in apocrine carcinoma of the breast. (19132986)
2008
10
15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. (18632593)
2008
11
Apocrine carcinomas of the breast in Turkish women: hormone receptors, c-erbB-2 and p53 immunoexpression. (18342452)
2008
12
Expression of oestrogen receptor-beta in apocrine carcinomas of the breast. (17448017)
2007
13
Apocrine adenoma of the breast coexistent with invasive carcinoma. (17936522)
2007
14
Molecular pathology of breast apocrine carcinomas: a protein expression signature specific for benign apocrine metaplasia. (16631754)
2006
15
Comparative study of monoclonal antibody B72.3 and gross cystic disease fluid protein-15 as markers of apocrine carcinoma of the breast. (17004974)
2006
16
Expression of GCDFP-15 and AR decreases in larger or node-positive apocrine carcinomas of the breast. (16045781)
2005
17
Cytology of pleomorphic lobular carcinoma with apocrine cell differentiation of the breast. A case report. (12685199)
2003
18
Histological and immunohistochemical analysis of apocrine breast carcinoma. (12196721)
2002
19
Expression of apocrine differentiation markers in neuroendocrine breast carcinomas of aged women. (11504836)
2001
20
Apocrine ductal carcinoma in situ of the breast: histologic classification and expression of biologic markers. (11381366)
2001
21
Androgen receptor CAG repeat lengths in ductal carcinoma in situ of breast, longest in apocrine variety. (14731580)
2000
22
Loss of heterozygosity is detected at chromosomes 1p35-36 (NB), 3p25 (VHL), 16p13 (TSC2/PKD1), and 17p13 (TP53) in microdissected apocrine carcinomas of the breast. (10619258)
1999
23
Immunohistochemical analysis of apocrine breast lesions. Consistent over-expression of androgen receptor accompanied by the loss of estrogen and progesterone receptors in apocrine metaplasia and apocrine carcinoma in situ. (9521507)
1997
24
The apocrine carcinoma of the breast. A cytological, immunohistochemical and ultrastructural study of 6 cases. (7524651)
1994
25
PIP/GCDFP-15 gene expression and apocrine differentiation in carcinomas of the breast. (7850069)
1994
26
Microglandular adenosis, apocrine adenosis, and tubular carcinoma of the breast. An immunohistochemical comparison. (8422116)
1993
27
Pleomorphic lobular carcinoma of the breast: an aggressive tumor showing apocrine differentiation. (1592388)
1992
28
Is apocrine differentiation in breast carcinoma of prognostic significance? (2202419)
1990
29
Breast carcinoma, apocrine variety]. (1966399)
1990
30
Extramammary Paget's disease: comparative histopathologic studies of intraductal carcinoma of the breast and apocrine adenocarcinoma. (2175320)
1990
31
Male breast cancer: a case of apocrine carcinoma with psammoma bodies. (7286970)
1981
32
APOCRINE GLAND CARCINOMA (SWEAT GLAND CARCINOMA) OF THE BREAST. (14119212)
1964
33
Apocrine gland carcinoma (sweat gland carcinoma) of the breast. (5276056)
1964
34
Apocrine tissue, chronic cystic mastitis and sweat gland carcinoma of the breast. (18104212)
1949

Genetic Variations for Breast Apocrine Carcinoma

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Expression for genes affiliated with Breast Apocrine Carcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Breast Apocrine Carcinoma

Search GEO for disease gene expression data for Breast Apocrine Carcinoma.

Pathways for genes affiliated with Breast Apocrine Carcinoma

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Compounds for genes affiliated with Breast Apocrine Carcinoma

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44Novoseek, 24HMDB
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Compounds related to Breast Apocrine Carcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1retinoic acid44 2410.1TP53, S100A7
2estrogen448.8TP53, S100A7

GO Terms for genes affiliated with Breast Apocrine Carcinoma

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16Gene Ontology
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Cellular components related to Breast Apocrine Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulumGO:0057839.1TP53, S100A7

Products for genes affiliated with Breast Apocrine Carcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Breast Apocrine Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet