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MCID: BRS047
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Breast Cancer malady |
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58 drugs, 3719 genes, 46 tissues, 1118 related diseases, 29 phenotypes, 16611 articles, clinical trials.
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Sources: 6Disease Ontology, 23MedlinePlus, 2CDC, 17Genetics Home Reference, 44Wikipedia, 33OMIM, 22MalaCards See all sources Export this MalaCard |
MedlinePlus: Breast cancer affects one in eight women during their lives. breast cancer kills more women in the united states than any cancer except lung cancer. no one knows why some women get breast cancer, but there are a number of risk factors. risks that you cannot change include
age - the chance of getting breast cancer rises as a woman gets older
genes - there are two genes, brca1 and brca2, that greatly increase the risk. women who have family members with breast or ovarian cancer may wish to be tested.
personal factors - beginning periods before age 12 or going through menopause after age 55
other risks include being overweight, using hormone replacement therapy (also called menopausal hormone therapy), taking birth control pills, drinking alcohol, not having children or having your first child after age 35 or having dense breasts.
symptoms of breast cancer may include a lump in the breast, a change in size or shape of the breast or discharge from a nipple. breast self-exam and mammography can help find breast cancer early when it is most treatable. treatment may consist of radiation, lumpectomy, mastectomy, chemotherapy and hormone therapy.
men can have breast cancer, too, but the number of cases is small.
nih: national cancer institute23
MalaCards: Breast Cancer, also known as malignant neoplasm of breast, is related to carcinoma and prostatitis. An important gene associated with Breast Cancer is BCAR3 (breast cancer anti-estrogen resistance 3), and among its related pathways are Metabolic pathways and Akt Signaling. The drugs ifosfamide and vinorelbine and the compounds atp and progesterone have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, whole blood and lymph node, and related mouse phenotypes are homeostasis/metabolism and cellular. Disease Ontology: A thoracic cancer that originates in the mammary gland.6 CDC: In the United States in 2008,* 210,203 women were diagnosed with breast cancer, and 40,589 women died from the disease.† Except for skin cancer, breast cancer is the most common cancer among American women. CDC supports breast cancer surveillance and research, and provides free or low-cost mammograms to underserved women.2 Genetics Home Reference: Breast cancer is a disease in which certain cells in the breast become abnormal and multiply without control or order to form a tumor. The most common form of breast cancer begins in cells lining the ducts that carry milk to the nipple (ductal cancer). Other forms of breast cancer begin in the glands that produce milk (lobular cancer) or in other parts of the breast.17 Wikipedia: Breast cancer is a type of cancer originating from breast tissue, most commonly from the inner lining of...44 more... OMIM: 114480 |
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Sources: 6Disease Ontology, 7diseasecard, 44Wikipedia, 17Genetics Home Reference, 8DISEASES, 33OMIM, 32Novoseek , 23MedlinePlus, 2CDC, 43UMLS, 40SNOMED-CT, 27NCIt, 24MeSH See all sources |
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Sources: 33OMIM See all sources |
Clinical features from OMIM: 114480
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for breast cancer Drug clinical trials:Search ClinicalTrials for breast cancer Search NIH Clinical Center for breast cancer Search CenterWatch for breast cancer Inferred drug relations via UMLS/NDF-RT:43 28 aminoglutethimide, anastrozole, capecitabine, carboplatin, chlorambucil, cisplatin, cisplatin pwdr [va product], cyclophosphamide, dexrazoxane, docetaxel, doxorubicin, doxorubicin hydrochloride, doxorubicin hydrochloride liposome, epirubicin, epirubicin hcl, exemestane, fluorouracil, fluoxymesterone, fulvestrant, goserelin acetate, idarubicin, idarubicin hydrochloride, ifosfamide, irinotecan, irinotecan hydrochloride, letrozole, leuprolide, leuprolide acetate, medroxyprogesterone, medroxyprogesterone acetate, megestrol, megestrol acetate, melphalan, melphalan hydrochloride, methotrexate, methotrexate sodium, methyltestosterone, methyltestosterone pwdr [va product], mitoxantrone, mitoxantrone hydrochloride, paclitaxel, sargramostim, tamoxifen, tamoxifen citrate, testolactone, testosterone, testosterone cypionate, testosterone enanthate, testosterone propionate, testosterone propionate pwdr [va product], testosterone pwdr [va product], toremifene, toremifene citrate, trastuzumab, vinblastine, vinblastine sulfate, vinorelbine, vinorelbine tartrate |
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to breast cancer:22Bone marrow, Whole blood, Lymph node, Spleen, Thymus, Brain, Cortex, Spinal cord, Heart, Smooth muscle, Skeletal muscle, Small intestine, Colon, Adipocyte, Kidney, Liver, Lung, Pancreas, Thyroid, Salivary gland, Adrenal gland, Breast, Skin, Ovary, Uterus, Placenta, Prostate, Testis, Cervix, Myeloid, Monocytes, Nk cells, T cells, B lymphoblasts, B cells, Endothelial, Fetal brain, Pons, Fetal liver, Fetal lung, Fetal thyroid, Adrenal cortex, Pineal, Pituitary, Uterus corpus, Testis germ
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to breast cancer:25 (show all 29)
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Sources: 35PubMed See all sources |
Articles related to breast cancer:(show top 50) (show all 16611)
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Sources: 1BioGPS See all sources |
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Sources: 20KEGG, 36QIAGEN, 3Cell Signaling Technology, 37R&D Systems, 41Thomson Reuters, 10EMD Millipore, 38Reactome See all sources |
Pathways related to breast cancer according to GeneDecks:(show top 50) (show all 480)
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Sources: 32Novoseek , 42Tocris Bioscience, 9DrugBank, 18HMDB, 34PharmGKB See all sources |
Compounds related to breast cancer according to GeneDecks:(show top 50) (show all 413)
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Sources: 12Gene Ontology See all sources |
Cellular components related to breast cancer according to GeneDecks:(show all 16)
Biological processes related to breast cancer according to GeneDecks:(show top 50) (show all 97)
Molecular functions related to breast cancer according to GeneDecks:(show all 22)
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