Aliases & Classifications for Breast Disease

Summaries for Breast Disease

MedlinePlus : 41 most women experience breast changes at some time. your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges (fluids that are not breast milk). if you have a breast lump, pain, discharge or skin irritation, see your health care provider. minor and serious breast problems have similar symptoms. although many women fear cancer, most breast problems are not cancer. some common breast changes are fibrocystic breast changes - lumpiness, thickening and swelling, often just before a woman's period cysts - fluid-filled lumps fibroadenomas - solid, round, rubbery lumps that move easily when pushed, occurring most in younger women intraductal papillomas - growths similar to warts near the nipple blocked milk ducts milk production when a woman is not breastfeeding nih: national cancer institute

MalaCards based summary : Breast Disease, also known as breast diseases, is related to mastitis and multiple fibroadenomas of the breast, and has symptoms including exanthema, mastodynia and pelvic pain. An important gene associated with Breast Disease is ESR1 (Estrogen Receptor 1), and among its related pathways/superpathways are TGF-Beta Pathway and Cytokine Signaling in Immune system. The drugs Letrozole and Toremifene have been mentioned in the context of this disorder. Affiliated tissues include breast, skin and prostate, and related phenotypes are behavior/neurological and endocrine/exocrine gland

Disease Ontology : 12 A thoracic disease that is located in the breast.

Wikipedia : 71 Breast diseases can be classified either with disorders of the integument, or disorders of the... more...

Related Diseases for Breast Disease

Diseases related to Breast Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
id Related Disease Score Top Affiliating Genes
1 mastitis 10.9
2 multiple fibroadenomas of the breast 10.7
3 microglandular adenosis 10.6
4 diabetic mastopathy 10.6
5 breast abscess 10.6
6 breast cancer 10.4
7 sohval soffer syndrome 10.3 IGF1 IGFBP3
8 bladder clear cell adenocarcinoma 10.3 CTSD ESR1 TP53
9 rhinitis 10.3 ESR1 KLK3 TP53
10 bone benign neoplasm 10.3 IGF1 PRL TP53
11 pituitary adenoma, acth-secreting 10.3 IGF1 IGFBP3 PRL
12 protein s deficiency 10.2 IGF1 IGFBP3 PRL
13 fallopian tube adenocarcinoma 10.2 ERBB2 ESR1 TP53
14 mouth disease 10.2 ERBB2 PGR
15 diencephalic neoplasm 10.2 PRL PRLR TP53
16 growth retardation hydrocephaly lung hypoplasia 10.2 ERBB2 PRL TP53
17 bartholin's gland benign neoplasm 10.2 ESR1 PGR
18 substance abuse 10.2 ERBB2 ESR1 ESR2 PRLR
19 aortitis 10.2 PGR TP53
20 dysbaric osteonecrosis 10.2 ESR1 ESR2 IGF1
21 bile acid synthesis defect, congenital, 4 10.2 IGF1 PRL PRLR
22 splenic infarction 10.2 ERBB2 ESR2 KLK3 TP53
23 chronic eosinophilic pneumonia 10.2 COMT ESR1 PRL
24 scapuloperoneal myopathy 10.2 ESR1 ESR2 IGF1
25 cardiovascular organ benign neoplasm 10.2 ESR1 PGR
26 appendix leiomyoma 10.2 ESR1 PGR
27 bronchus adenoma 10.2 ESR1 PGR
28 glioblastoma mesenchymal subtype 10.2 KLK3 PRL SHBG
29 villoglandular endometrial endometrioid adenocarcinoma 10.2 ESR1 PGR TP53
30 vaginal adenosarcoma 10.2 ESR1 PGR TP53
31 mucopolysaccharidosis 10.2 SOD2 TNF TP53
32 paraphimosis 10.2 ESR1 PGR TP53
33 plague 10.2 ERBB2 ESR1 TNF TP53
34 glioma 10.2 ERBB2 ESR1 PGR
35 cervical lymphoepithelioma-like carcinoma 10.2 ERBB2 ESR1 PGR
36 histiocytic and dendritic cell cancer 10.2 ERBB2 ESR1 PGR
37 congenital symblepharon 10.2 IGF1 IGFBP3 TP53
38 ulceroglandular tularemia 10.2 ESR1 ESR2 PRLR SHBG
39 nervous system hibernoma 10.2 ERBB2 ESR1 PGR
40 deafness, autosomal recessive 21 10.2 ESR1 ESR2 PGR
41 poliomyelitis 10.2 ERBB2 ESR1 PGR
42 cervix squamous papilloma 10.2 IGF1 IGFBP3 PRL
43 esophagus sarcoma 10.2 ESR1 KLK3 PGR
44 aphasia 10.2 KLK3 PRL SHBG
45 osteogenesis imperfecta 10.2 ESR1 ESR2 PGR
46 rectal neoplasm 10.2 ERBB2 ESR1 PGR
47 ovarian benign neoplasm 10.2 ESR1 PGR
48 epidural spinal canal meningioma 10.2 IGF1 PRL SHBG
49 combined t cell and b cell immunodeficiency 10.2 ERBB2 ESR1 PGR
50 anomalous left coronary artery from the pulmonary artery 10.2 ERBB2 ESR1 PGR

Graphical network of the top 20 diseases related to Breast Disease:



Diseases related to Breast Disease

Symptoms & Phenotypes for Breast Disease

UMLS symptoms related to Breast Disease:


exanthema, mastodynia, pelvic pain, pruritus, breast engorgement, nipple discharge, signs and symptoms in breast, other signs and symptoms in breast, breast pain female

MGI Mouse Phenotypes related to Breast Disease:

44 (show all 16)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.36 PRL PRLR SOD2 STAT5A TNF TP53
2 endocrine/exocrine gland MP:0005379 10.36 TP53 COMT CTSD CYP1A1 ERBB2 ESR1
3 homeostasis/metabolism MP:0005376 10.36 TNF TP53 COMT CTSD CYP1A1 CYP1B1
4 cellular MP:0005384 10.3 CTSD ERBB2 ESR1 ESR2 IGF1 PGR
5 cardiovascular system MP:0005385 10.28 COMT CTSD CYP1A1 ERBB2 ESR1 ESR2
6 growth/size/body region MP:0005378 10.27 CTSD CYP1A1 ERBB2 ESR1 ESR2 IGF1
7 immune system MP:0005387 10.25 CTSD CYP1A1 ESR1 ESR2 IGF1 PGR
8 hematopoietic system MP:0005397 10.22 PGR SOD2 STAT5A TNF TP53 COMT
9 integument MP:0010771 10.22 CTSD ERBB2 ESR1 ESR2 IGF1 IGFBP3
10 adipose tissue MP:0005375 10.21 ESR1 ESR2 IGF1 IGFBP3 PRLR SOD2
11 limbs/digits/tail MP:0005371 9.97 ESR1 ESR2 IGF1 PGR PRLR TNF
12 liver/biliary system MP:0005370 9.97 CYP1A1 ESR1 ESR2 IGFBP3 PRL SOD2
13 neoplasm MP:0002006 9.93 CYP1B1 ERBB2 ESR1 ESR2 IGF1 PGR
14 muscle MP:0005369 9.91 ERBB2 ESR1 ESR2 IGF1 IGFBP3 PGR
15 nervous system MP:0003631 9.7 COMT CTSD ERBB2 ESR1 ESR2 IGF1
16 reproductive system MP:0005389 9.4 ERBB2 ESR1 ESR2 IGF1 PGR PRL

Drugs & Therapeutics for Breast Disease

Drugs for Breast Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 859)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 112809-51-5 3902
2
Toremifene Approved, Investigational Phase 4,Phase 3,Phase 2 89778-26-7 3005573
3
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
4
Zoledronic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 118072-93-8 68740
5
Diazepam Approved, Illicit, Vet_approved Phase 4,Phase 2 439-14-5 3016
6
Anastrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 120511-73-1 2187
7
Exemestane Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 107868-30-4 60198
8
Tamoxifen Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10540-29-1 2733526
9
Trastuzumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 180288-69-1 9903
10
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
11
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
12
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
13
Epirubicin Approved Phase 4,Phase 2,Phase 3,Phase 1 56420-45-2 41867
14
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1 51-21-8 3385
15
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2 55-56-1 9552079 2713
16
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
17
Povidone-iodine Approved Phase 4,Phase 3 25655-41-8
18
Capecitabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 154361-50-9 60953
19
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
20
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
21
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
22
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 216974-75-3
23
Nitrous oxide Approved, Vet_approved Phase 4,Phase 3 10024-97-2 948
24
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
25
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
26
Vinblastine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 865-21-4 13342 241903
27
Vinorelbine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 71486-22-1 60780 44424639
28
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
29
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2 2180-92-9, 38396-39-3 2474
30
Fulvestrant Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 129453-61-8 104741 17756771
31
Palbociclib Approved Phase 4,Phase 3,Phase 2,Phase 1 571190-30-2 11431660 5005498 5330286
32
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-23-7 5754 657311
33
Pertuzumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 145040-37-5, 380610-27-5 2540
34
Technetium tc 99m sulfur colloid Approved Phase 4,Phase 2
35
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-28-2 5757 53477783
36
Goserelin Approved Phase 4,Phase 3,Phase 2,Phase 1 65807-02-5 47725 5311128
37
Iron Approved Phase 4,Phase 3,Phase 2,Early Phase 1 7439-89-6 23925
38
Bupropion Approved Phase 4 34841-39-9, 34911-55-2 444
39
Dopamine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 51-61-6, 62-31-7 681
40
Copper Approved Phase 4,Phase 2 15158-11-9, 7440-50-8 27099
41
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
42
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 50-02-2 5743
43
Ropivacaine Approved Phase 4,Phase 3 84057-95-4 71273 175805
44
Pamidronate Approved Phase 4,Phase 2 40391-99-9 4674
45
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
46
Sulbactam Approved Phase 4 68373-14-8
47
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
48
Etidronic acid Approved Phase 4,Phase 3 7414-83-7, 2809-21-4 3305
49
Triclosan Approved Phase 4 3380-34-5 5564
50
Aprepitant Approved, Investigational Phase 4,Phase 3 170729-80-3 151165 6918365

Interventional clinical trials:

(show top 50) (show all 5000)
id Name Status NCT ID Phase
1 Extended Adjuvant Treatment With Letrozole in Breast Cancer Who Complete 5 Years of Toremifene Unknown status NCT01072318 Phase 4
2 Clinical Outcomes After Letrozole Treatment According to the Estrogen Receptor Expression in Postmenopausal Women Unknown status NCT01069211 Phase 4
3 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4
4 A Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients With Taxane-Pretreated Recurrent Breast Cancer Unknown status NCT00912639 Phase 4
5 Benefits of Breast MRI for Predicting of Histopathologic Cell Type of Small Breast Cancer Unknown status NCT01597999 Phase 4
6 Assessment of Quality of Life, Bone Density and Safety in Postmenopausal Breast Cancer Patients With Letrozole Therapy Unknown status NCT00913016 Phase 4
7 Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients Unknown status NCT00912938 Phase 4
8 Study the Role of Positron Emission Mammography in Pre-surgical Planning for Breast Cancer Unknown status NCT00484614 Phase 4
9 Circulating miRNAs as Biomarkers of Hormone Sensitivity in Breast Cancer Unknown status NCT01612871 Phase 4
10 A Study of Patients With HER2 Gene Amplified Metastatic Breast Cancer Treated With First Line Herceptin and a Taxane Unknown status NCT00097487 Phase 4
11 STARS Breast Trial (Study of Anastrozole and Radiotherapy Sequencing Pilot) Unknown status NCT00126360 Phase 4
12 The MONET - Study: MR Mammography of Nonpalpable Breast Tumors Unknown status NCT00302120 Phase 4
13 Clinical Trial Comparing Outcomes of Breast Conserving Operations With Classic v High-frequency Electrocoagulation Unknown status NCT01216254 Phase 4
14 Yunzhi as Dietary Supplement in Breast Cancer Unknown status NCT00647075 Phase 4
15 Pharmacogenetics as a Predictor of Toxicity in Pre-Menopausal Women Receiving Doxorubicin and Cyclophosphamide in Early Breast Cancer Unknown status NCT00352872 Phase 4
16 Paclitaxel in Combination With Carboplatin Versus Paclitaxel Plus Epirubicin in Metastatic Breast Cancer Unknown status NCT02207361 Phase 4
17 Study of the Effect of Glutamine Supplementation on Chemotherapy Induced Toxicities in Breast Cancer Patients Unknown status NCT00772824 Phase 4
18 A Study of Liposomal Doxorubicin in Women With Breast Cancer Exploiting Tissue Doppler Imaging Unknown status NCT00531973 Phase 4
19 Weekly and Every 3 Week Administration of Paclitaxel Liposome Injection in Metastatic Breast Cancer Unknown status NCT02142790 Phase 4
20 Wound Infections in Breast Cancer Surgery After Preoperative Skin Preparation With Chlorhexidine vs. Povidone-iodine Unknown status NCT02479347 Phase 4
21 Omega-3 Fatty Acids and Chemotherapy-induced Neuropathy and Inflammation in Breast Cancer Unknown status NCT01049295 Phase 4
22 EAP (Expanded Access Protocol) Of Lapatinib Combined With Capecitabine In Metastatic Breast Cancer Approved for marketing NCT00338247 Phase 4
23 Effects of Tamoxifen in Premenopausal Women With Benign Breast Disease Not at High-Risk of Developing Breast Cancer Completed NCT00999921 Phase 4
24 An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis Completed NCT01743560 Phase 4
25 Eribulin Mesylate Phase IV Clinical Trial in Korean Patients With Metastatic or Locally Advanced Breast Cancer Completed NCT01961544 Phase 4
26 A Study of Xeloda (Capecitabine) in Women With HER2-Negative Metastatic Breast Cancer Completed NCT00121836 Phase 4
27 Arthralgia During Anastrozole Therapy for Breast Cancer Completed NCT00323479 Phase 4
28 A Study of Avastin With Taxane Therapy in Patients With Triple Negative Breast Cancer Completed NCT01094184 Phase 4
29 An Observational Study of Treatment Patterns and Safety Outcomes for Metastatic or Locally Recurrent Breast Cancer (VIRGO) Completed NCT00726661 Phase 4
30 Liver Safety Under Upfront Arimidex vs Tamoxifen Completed NCT00537771 Phase 4
31 Maintenance Treatment With Liposomal Doxorubicin (Caelyx) in Metastatic Breast Cancer Patients Completed NCT00128778 Phase 4
32 A Study of Herceptin (Trastuzumab) in Combination With a Taxane in Participants With HER2-Positive Breast Cancer Who Relapsed After (Neo)Adjuvant Herceptin Treatment Completed NCT01301729 Phase 4
33 Wellbutrin XL, Major Depressive Disorder and Breast Cancer Completed NCT00234195 Phase 4
34 Life Quality and Mental State in Patients With Breast Cancer Completed NCT01458457 Phase 4
35 Study Comparing Full-dose Radiotherapy Versus Reduced Dose in the Management of Bone Metastasis in Patients With Breast Cancer Receiving Zoledronic Acid Completed NCT00172029 Phase 4
36 Accelerated Radiotherapy Outcomes in Women Completed NCT00156130 Phase 4
37 XeNA Study - A Study of Xeloda (Capecitabine) in Patients With Invasive Breast Cancer Completed NCT00127933 Phase 4
38 Will Preoperative MRI Breast in Women Under 56 Years With Breast Cancer Change Primary Treatment Completed NCT01859936 Phase 4
39 Case-Control-Study on the Breast Cancer Risk of Mirena® Compared With Copper IUDs Completed NCT00461253 Phase 4
40 Use of the Contura™ Catheter to Deliver Accelerated Partial Breast Irradiation to "Low-risk" Breast Cancer Patients Completed NCT00882596 Phase 4
41 Comparative Efficiency of Three Regimen, CEFci, CEF and EC as Neoadjuvant Chemotherapy for Primary Breast Cancer Completed NCT01199432 Phase 4
42 Randomized Trial of Follow-up Strategies in Breast Cancer Completed NCT00156039 Phase 4
43 Research Of Quality Of Life And Safety Outcomes Of Postmenopausal Breast Cancer Patients Switching From Tamoxifen Therapy To Aromatase Inhibitor Therapy Completed NCT00784888 Phase 4
44 Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy Completed NCT01817374 Phase 4
45 Open Label Study of Postmenopausal Women With ER and /or PgR Positive Breast Cancer Treated With Letrozole Completed NCT00237224 Phase 4
46 Wound Infiltration and Breast Cancer Surgery Completed NCT01404377 Phase 4
47 Letrozole in Treating Postmenopausal Women With Metastatic Breast Cancer Completed NCT00014638 Phase 4
48 The ODYSSEY TRIAL Phase IV Trial Evaluating the Palliative Benefit of Pamidronate or Zoledronic Acid in Breast Cancer Completed NCT01907880 Phase 4
49 The Efficacy of Prophylactic Antibiotic Administration During Breast Cancer Surgery in Overweight Patients. Completed NCT00356148 Phase 4
50 Feasibility Study for the Determination of Oxysterols in Patients With Breast Cancer Receiving Hormonal Therapy With Tamoxifen or Not Completed NCT01553903 Phase 4

Search NIH Clinical Center for Breast Disease

Cochrane evidence based reviews: breast diseases

Genetic Tests for Breast Disease

Genetic tests related to Breast Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Breast 29

Anatomical Context for Breast Disease

MalaCards organs/tissues related to Breast Disease:

39
Breast, Skin, Prostate, Testes, Thyroid, Lymph Node, Ovary

The Foundational Model of Anatomy Ontology organs/tissues related to Breast Disease:

18
The Breast

Publications for Breast Disease

Articles related to Breast Disease:

(show top 50) (show all 578)
id Title Authors Year
1
Breast Disease Treatment in a US Military Hospital in Afghanistan. ( 27696612 )
2017
2
Society of Surgical Oncology Breast Disease Working Group Statement on Prophylactic (Risk-Reducing) Mastectomy. ( 27933411 )
2017
3
Cowden Syndrome: Serendipitous Diagnosis in Patients with Significant Breast Disease. Case Series and Literature Review. ( 27886412 )
2017
4
Body size from birth through adolescence in relation to risk of benign breast disease in young women. ( 28062981 )
2017
5
Association Between Benign Breast Disease in African American and White American Women and Subsequent Triple-Negative Breast Cancer. ( 28006062 )
2016
6
Inflammatory breast disease: A pictorial essay with radiological-pathological correlation. ( 27324090 )
2016
7
Lower Serum Levels of Uric Acid in Uterine Fibroids and Fibrocystic Breast Disease Patients in Dongying City, China. ( 27398332 )
2016
8
Assessing the Relationship of Mammographic Breast Density and Proliferative Breast Disease. ( 27261096 )
2016
9
Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease. ( 26893016 )
2016
10
The United States' national accreditation program for breast centers: a model for excellence in breast disease evaluation and management. ( 27157999 )
2016
11
A prospective study of endometriosis and risk of benign breast disease. ( 27604359 )
2016
12
Difference in fatty acids composition of breast adipose tissue in women with breast cancer and benign breast disease. ( 28000465 )
2016
13
Downregulation of GLUT4 contributes to effective intervention of estrogen receptor-negative/HER2-overexpressing early stage breast disease progression by lapatinib. ( 27293993 )
2016
14
Standardized measures of lobular involution and subsequent breast cancer risk among women with benign breast disease: a nested case-control study. ( 27488681 )
2016
15
Breast Disease. Management and Therapies. ( 27466592 )
2016
16
Benign and Malignant Breast Disease at Rwanda's First Public Cancer Referral Center. ( 27009935 )
2016
17
Complex fibroadenoma and breast cancer risk: a Mayo Clinic Benign Breast Disease Cohort Study. ( 26264469 )
2015
18
Breast cancer risk associated with benign breast disease: systematic review and meta-analysis. ( 25636589 )
2015
19
Benign breast disease and the risk of breast cancer in the next 15 years. ( 25970956 )
2015
20
Impact of preventive therapy on the risk of breast cancer among women with benign breast disease. ( 26255741 )
2015
21
Emotional personality/proximity versus emotional authenticity in patient-physician communication in healthy study participants, and in patients with benign breast disease, and breast cancer: a prospective case-control study in Finland. ( 25750320 )
2015
22
Agreement between hopelessness/helplessness and montgomery-asberg depression rating scale in healthy individuals and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland. ( 25862881 )
2015
23
Correlation of serum toll like receptor 9 and trace elements with lipid peroxidation in the patients of breast diseases. ( 25744504 )
2015
24
Breast disease in children and adolescents. ( 25739116 )
2015
25
Inflammatory breast disease: The radiologist's role. ( 26372222 )
2015
26
Clinicopathologic features of breast cancers that develop in women with previous benign breast disease. ( 26512815 )
2015
27
Adolescent dietary vitamin D and sun exposure in relation to benign breast disease. ( 26084210 )
2015
28
Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: a study from a population-based screening program. ( 25503778 )
2015
29
Is the Benign Breast Disease Breast Cancer Model Well Calibrated? ( 26215936 )
2015
30
Breast Density and Benign Breast Disease: Risk Assessment to Identify Women at High Risk of Breast Cancer. ( 26282663 )
2015
31
Relationship between elasticity and collagen fiber content in breast disease: a preliminary report. ( 25465961 )
2015
32
Suicidal Ideation Versus Hopelessness/Helplessness in Healthy Individuals and in Patients with Benign Breast Disease and Breast Cancer: A Prospective Case-control Study in Finland. ( 26026123 )
2015
33
The prevalence of benign breast diseases in patients with nodular goiter and Hashimoto's thyroiditis. ( 25827711 )
2015
34
Prenatal factors and infant feeding in relation to risk of benign breast disease in young women. ( 26582399 )
2015
35
Spectrum of breast disease in an urban general surgical centre in India. ( 25881642 )
2015
36
Ki-67 expression in sclerosing adenosis and adjacent normal breast terminal ductal lobular units: a nested case-control study from the Mayo Benign Breast Disease Cohort. ( 25863475 )
2015
37
The relation of hopelessness/helplessness versus beck depression inventory (BDI) in healthy individuals and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland. ( 25667478 )
2015
38
Anger in health, benign breast disease and breast cancer: a prospective case-control study. ( 25189916 )
2014
39
p40 (I9Np63) expression in breast disease and its correlation with p63 immunohistochemistry. ( 24696720 )
2014
40
Expression of serum toll-like receptor 9 and oxidative damage markers in benign and malignant breast diseases. ( 24906089 )
2014
41
Metastatic breast disease from cutaneous malignant melanoma. ( 24394861 )
2014
42
Breast Ultrasound Elastography and Magnetic Resonance Imaging of Fibrotic Changes of Breast Disease: Correlations Between Elastography Findings and Pathologic and Short Tau Inversion Recovery Imaging Results, Including the Enhancement Ratio and Apparent Diffusion Coefficient. ( 25299798 )
2014
43
Clinical and imaging features of male breast disease, with pathological correlation: a pictorial essay. ( 24690244 )
2014
44
Clinical characteristics of breast cancers in african-american women with benign breast disease: a comparison to the surveillance, epidemiology, and end results program. ( 25200244 )
2014
45
Circulating cell-free cancer-testis MAGE-A RNA, BORIS RNA, let-7b and miR-202 in the blood of patients with breast cancer and benign breast diseases. ( 24983365 )
2014
46
The self-rating score (SRS) versus the examiner rating score (ERS) in measuring helplessness in healthy individuals and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland. ( 25275073 )
2014
47
Contribution of emotional distance and reserve in patient-physician communication in healthy study patients, and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland. ( 24596371 )
2014
48
Re: establishment of novel rat models for premalignant breast disease. ( 25533839 )
2014
49
Insulin, estrogen, inflammatory markers, and risk of benign proliferative breast disease. ( 24755474 )
2014
50
Adolescent carotenoid intake and benign breast disease. ( 24709924 )
2014

Variations for Breast Disease

Expression for Breast Disease

Search GEO for disease gene expression data for Breast Disease.

Pathways for Breast Disease

Pathways related to Breast Disease according to GeneCards Suite gene sharing:

(show all 31)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.49 ERBB2 IGF1 PPP2R5E PRL PRLR STAT5A
2
Show member pathways
13.3 ERBB2 PPP2R5E PRL PRLR STAT5A TNF
3
Show member pathways
13.13 ERBB2 IGF1 PRL PRLR RHOC STAT5A
4
Show member pathways
12.62 ERBB2 ESR1 ESR2 IGF1 KLK3 PGR
5 12.6 ERBB2 IGF1 KLK3 STAT5A TP53
6 12.5 IGF1 PPP2R5E PRL PRLR TP53
7
Show member pathways
12.32 IGF1 IGFBP3 STAT5A TP53
8
Show member pathways
12.28 ERBB2 IGF1 STAT5A TP53
9
Show member pathways
12.25 ERBB2 ESR1 ESR2 IGF1
10 12.07 ERBB2 ESR1 IGF1 TNF TP53
11 11.95 IGF1 PRLR STAT5A TNF
12
Show member pathways
11.95 CTSD ERBB2 ESR1 ESR2 PRL PRLR
13 11.87 CTSD PPP2R5E TNF TP53
14 11.82 ERBB2 PPP2R5E SOD2 TP53
15
Show member pathways
11.77 ESR1 ESR2 PGR
16 11.72 PRL STAT5A TP53
17
Show member pathways
11.59 COMT CYP1A1 CYP1B1
18 11.47 CYP1A1 CYP1B1 IGF1
19 11.46 PRL PRLR STAT5A
20 11.43 CYP1A1 CYP1B1 TNF
21 11.36 CTSD ESR1 TP53
22
Show member pathways
11.34 PRL PRLR STAT5A
23 11.24 CYP1A1 CYP1B1 ESR1 TNF
24
Show member pathways
11.22 COMT CYP1A1 CYP1B1
25 11.16 ESR2 PGR PRLR
26
Show member pathways
11.13 ERBB2 ESR1 PGR PRL PRLR STAT5A
27 11.06 ESR1 ESR2 SOD2
28 10.9 IGF1 IGFBP3 KLK3
29 10.61 CYP1A1 CYP1B1 ESR1
30 10.57 PRL TNF
31 10.14 ESR1 ESR2

GO Terms for Breast Disease

Cellular components related to Breast Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.81 CTSD ESR2 IGF1 IGFBP3 KLK3 PRL
2 insulin-like growth factor ternary complex GO:0042567 8.96 IGF1 IGFBP3
3 insulin-like growth factor binding protein complex GO:0016942 8.62 IGF1 IGFBP3

Biological processes related to Breast Disease according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.78 IGF1 IGFBP3 KLK3 PRL
2 cell proliferation GO:0008283 9.72 CYP1A1 ERBB2 IGF1 PRL TP53
3 response to lipopolysaccharide GO:0032496 9.71 COMT CYP1A1 PRL SOD2
4 cellular response to organic cyclic compound GO:0071407 9.69 CYP1A1 CYP1B1 TNF
5 positive regulation of epithelial cell proliferation GO:0050679 9.61 ERBB2 IGF1 PRL
6 positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 9.54 IGF1 IGFBP3
7 steroid hormone mediated signaling pathway GO:0043401 9.54 ESR1 ESR2 PGR
8 estrogen metabolic process GO:0008210 9.52 COMT CYP1B1
9 hydrogen peroxide biosynthetic process GO:0050665 9.49 CYP1A1 SOD2
10 omega-hydroxylase P450 pathway GO:0097267 9.46 CYP1A1 CYP1B1
11 lactation GO:0007595 9.43 PRL PRLR STAT5A
12 prolactin signaling pathway GO:0038161 9.16 PRLR STAT5A
13 regulation of multicellular organism growth GO:0040014 9.13 IGF1 PRL STAT5A
14 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 8.8 PRL PRLR STAT5A

Molecular functions related to Breast Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 steroid hormone receptor activity GO:0003707 9.63 ESR1 ESR2 PGR
2 oxygen binding GO:0019825 9.61 CYP1A1 CYP1B1 SOD2
3 core promoter sequence-specific DNA binding GO:0001046 9.54 ESR1 ESR2 TP53
4 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879 9.5 ESR1 ESR2 PGR
5 enzyme binding GO:0019899 9.43 CYP1A1 ESR1 ESR2 PGR SOD2 TP53
6 estrogen receptor activity GO:0030284 9.4 ESR1 ESR2
7 estrogen response element binding GO:0034056 9.26 ESR1 ESR2
8 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding GO:0038052 9.16 ESR1 ESR2
9 steroid binding GO:0005496 8.92 ESR1 ESR2 PGR SHBG
10 protein binding GO:0005515 10.41 COMT CTSD CYP1A1 ERBB2 ESR1 ESR2

Sources for Breast Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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