Aliases & Classifications for Breast Disease

MalaCards integrated aliases for Breast Disease:

Name: Breast Disease 12 14
Breast Diseases 52 41 42 69
Abnormality of the Breast 29

Classifications:



Summaries for Breast Disease

MedlinePlus : 41 most women experience breast changes at some time. your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges (fluids that are not breast milk). if you have a breast lump, pain, discharge or skin irritation, see your health care provider. minor and serious breast problems have similar symptoms. although many women fear cancer, most breast problems are not cancer. some common breast changes are fibrocystic breast changes - lumpiness, thickening and swelling, often just before a woman's period cysts - fluid-filled lumps fibroadenomas - solid, round, rubbery lumps that move easily when pushed, occurring most in younger women intraductal papillomas - growths similar to warts near the nipple blocked milk ducts milk production when a woman is not breastfeeding nih: national cancer institute

MalaCards based summary : Breast Disease, also known as breast diseases, is related to endometriosis and ductal carcinoma in situ, and has symptoms including exanthema, mastodynia and pelvic pain. An important gene associated with Breast Disease is PRLR (Prolactin Receptor), and among its related pathways/superpathways are IL-2 Pathway and Pathways in cancer. The drugs Letrozole and Toremifene have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and lymph node, and related phenotypes are behavior/neurological and homeostasis/metabolism

Disease Ontology : 12 A thoracic disease that is located in the breast.

Wikipedia : 72 Breast diseases can be classified either with disorders of the integument, or disorders of the... more...

Related Diseases for Breast Disease

Diseases related to Breast Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 174)
id Related Disease Score Top Affiliating Genes
1 endometriosis 29.7 KLK3 PRL SHBG
2 ductal carcinoma in situ 29.1 ERBB2 ESR1 KRT5 PGR TP53
3 mastitis 11.0
4 diabetic mastopathy 11.0
5 small cell lung cancer, childhood 10.9 IGF1 IGFBP3
6 fallopian tube clear cell adenocarcinoma 10.8 CTSD ESR1 TP53
7 malt worker's lung 10.8 KLK3 TP53
8 selenium poisoning 10.8 IGF1 IGFBP3
9 brenner tumor of the vagina 10.7 ERBB2 ESR1 TP53
10 brenner tumor of ovary 10.7 ERBB2 ESR1 TP53
11 multiple fibroadenomas of the breast 10.7
12 congenital disorder of glycosylation, type if 10.7 ERBB2 TP53
13 acute cholinergic dysautonomia 10.7 TNF TP53
14 congenital hypomyelination neuropathy 10.7 IGF1 IGFBP3 TP53
15 fallopian tube mucinous tumor 10.6 ERBB2 ESR1 TP53
16 microglandular adenosis 10.6
17 immune system organ benign neoplasm 10.6 IGF1 PRL TP53
18 diencephalic neoplasm 10.6 PRL PRLR TP53
19 protein s deficiency 10.6 IGF1 IGFBP3 PRL
20 blastema predominant kidney wilms' tumor 10.6 PGR TP53
21 pituitary adenoma, prolactin-secreting 10.6 IGF1 IGFBP3 PRL
22 lipid-cell variant infiltrating bladder urothelial carcinoma 10.6 KRT5 TP53
23 ulcerative colitis 10.6 COMT IGF1 TNF
24 alpha-methylacyl-coa racemase deficiency 10.6 IGF1 PRL PRLR
25 bladder tuberculosis 10.6 ERBB2 KRT5
26 group b strep disease in newborns 10.6 ERBB2 PRL TP53
27 bartholin's gland benign neoplasm 10.6 ESR1 PGR
28 breast abscess 10.6
29 gastritis 10.5 ERBB2 PGR
30 gallbladder leiomyoma 10.5 ESR1 PGR
31 male reproductive organ benign neoplasm 10.5 IGF1 PRL TP53
32 benign shuddering attacks 10.5 ESR1 IGFBP3 TP53
33 nerve fibre bundle defect 10.5 ERBB2 ESR1
34 breast sarcoma 10.5 ERBB2 ESR1 ESR2 PRLR
35 fallopian tube benign neoplasm 10.5 ESR1 PGR
36 paranasal sinus disease 10.5 ESR1 PGR
37 dartoic leiomyoma 10.5 ESR1 PGR
38 prostate leiomyoma 10.5 PRL PRLR
39 endocervicitis 10.5 ERBB2 TP53
40 chronic dacryoadenitis 10.5 COMT ESR1 PRL
41 splenic infarction 10.5 ERBB2 ESR2 KLK3 TP53
42 prostate cancer, hereditary, x-linked 1 10.5 CYP1A1 ESR2 TP53
43 allergic asthma 10.5 IGF1 IGFBP3 PRL
44 vallecula cancer 10.5 COMT IGF1 TNF
45 central nervous system organ benign neoplasm 10.5 ESR1 PGR TP53
46 lung adenoma 10.5 ESR1 PGR TP53
47 intestinal perforation 10.4 ESR1 PGR TP53
48 ovarian mesodermal adenosarcoma 10.4 ESR1 PGR TP53
49 chest wall lymphoma 10.4 ESR1 PGR TP53
50 retinal detachment 10.4 ESR1 PGR TP53

Graphical network of the top 20 diseases related to Breast Disease:



Diseases related to Breast Disease

Symptoms & Phenotypes for Breast Disease

UMLS symptoms related to Breast Disease:


exanthema, mastodynia, pelvic pain, pruritus, breast engorgement, nipple discharge, signs and symptoms in breast, other signs and symptoms in breast, breast pain female

MGI Mouse Phenotypes related to Breast Disease:

44 (show all 19)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.42 COMT CTSD ERBB2 ESR1 ESR2 IGFBP3
2 homeostasis/metabolism MP:0005376 10.41 COMT CTSD CYP1A1 CYP1B1 ERBB2 ESR1
3 endocrine/exocrine gland MP:0005379 10.39 ESR1 ESR2 IGF1 IGFBP3 PGR PRL
4 growth/size/body region MP:0005378 10.35 CTSD CYP1A1 ERBB2 ESR1 ESR2 IGF1
5 cellular MP:0005384 10.34 IGF1 PGR PRLR RHOC SOD2 STAT5A
6 integument MP:0010771 10.32 CTSD ERBB2 ESR1 ESR2 IGF1 IGFBP3
7 immune system MP:0005387 10.31 TP53 CTSD CYP1A1 ESR1 ESR2 IGF1
8 cardiovascular system MP:0005385 10.27 COMT CYP1A1 ERBB2 ESR1 ESR2 IGF1
9 hematopoietic system MP:0005397 10.26 COMT CTSD CYP1A1 ESR1 ESR2 IGF1
10 adipose tissue MP:0005375 10.24 ESR1 ESR2 IGF1 IGFBP3 PRLR SOD2
11 neoplasm MP:0002006 10.15 ERBB2 ESR1 ESR2 IGF1 PGR PRL
12 limbs/digits/tail MP:0005371 10.11 ERBB2 ESR1 ESR2 IGF1 KRT5 PGR
13 liver/biliary system MP:0005370 10.09 CYP1A1 ESR1 ESR2 IGFBP3 PRL SOD2
14 muscle MP:0005369 10.06 TNF TP53 ERBB2 ESR1 ESR2 IGF1
15 nervous system MP:0003631 10.06 ERBB2 ESR1 ESR2 IGF1 PRL PRLR
16 reproductive system MP:0005389 9.93 PRLR SOD2 STAT5A TNF TP53 COMT
17 renal/urinary system MP:0005367 9.73 COMT ESR1 ESR2 IGF1 SOD2 TP53
18 respiratory system MP:0005388 9.5 COMT ERBB2 ESR1 ESR2 IGF1 TNF
19 skeleton MP:0005390 9.23 ERBB2 ESR1 ESR2 IGF1 PGR PRLR

Drugs & Therapeutics for Breast Disease

Drugs for Breast Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 960)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 112809-51-5 3902
2
Toremifene Approved, Investigational Phase 4,Phase 3,Phase 2 89778-26-7 3005573
3
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
4
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2 55-56-1 9552079 2713
5
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
6
Povidone Approved Phase 4,Phase 2 9003-39-8
7 Povidone-iodine Approved Phase 4,Phase 3 25655-41-8
8
Zoledronic acid Approved Phase 4,Phase 2,Phase 3,Phase 1 118072-93-8 68740
9
Diazepam Approved, Illicit, Vet_approved Phase 4,Phase 2,Phase 1 439-14-5 3016
10
Anastrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 120511-73-1 2187
11
Exemestane Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 107868-30-4 60198
12
Tamoxifen Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10540-29-1 2733526
13
Trastuzumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 180288-69-1 9903
14
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
15
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
16
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 41575-94-4 10339178 498142 38904
17
Epirubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 56420-45-2 41867
18
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1 51-21-8 3385
19
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
20
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
21
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
22
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1 103-90-2 1983
23
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2 2180-92-9, 38396-39-3 2474
24
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 51-43-4 5816
25
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 437-38-7 3345
26
Ketorolac Approved Phase 4,Phase 3 74103-06-3, 66635-83-4 3826
27
Morphine Approved, Investigational Phase 4 57-27-2 5288826
28
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 2078-54-8 4943
29 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Early Phase 1
30
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
31
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
32
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
33
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 216974-75-3
34
Capecitabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 154361-50-9 60953
35
Fulvestrant Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 129453-61-8 104741 17756771
36
Nitrous oxide Approved, Vet_approved Phase 4,Phase 3 10024-97-2 948
37
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
38
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
39
Vinblastine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 865-21-4 13342 241903
40
Vinorelbine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 71486-22-1 60780 44424639
41
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2 137-58-6 3676
42
Goserelin Approved Phase 4,Phase 3,Phase 2,Phase 1 65807-02-5 47725 5311128
43
Palbociclib Approved Phase 4,Phase 3,Phase 2,Phase 1 571190-30-2 11431660 5005498 5330286
44
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-23-7 5754 657311
45
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757
46
Iron Approved Phase 4,Phase 3,Phase 2,Early Phase 1 7439-89-6 23925
47
Bupropion Approved Phase 4,Phase 2 34841-39-9, 34911-55-2 444
48
Dopamine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 51-61-6, 62-31-7 681
49
Copper Approved Phase 4,Phase 2,Phase 1 7440-50-8 27099
50
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109

Interventional clinical trials:

(show top 50) (show all 6306)

id Name Status NCT ID Phase Drugs
1 Extended Adjuvant Treatment With Letrozole in Breast Cancer Who Complete 5 Years of Toremifene Unknown status NCT01072318 Phase 4 Letrozole
2 Clinical Outcomes After Letrozole Treatment According to the Estrogen Receptor Expression in Postmenopausal Women Unknown status NCT01069211 Phase 4
3 Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace) Unknown status NCT01908556 Phase 4 Letrozole
4 A Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients With Taxane-Pretreated Recurrent Breast Cancer Unknown status NCT00912639 Phase 4 Paclitaxel loaded Polymeric micelle
5 Wound Infections in Breast Cancer Surgery After Preoperative Skin Preparation With Chlorhexidine vs. Povidone-iodine Unknown status NCT02479347 Phase 4 Chlorhexidine;Povidone-Iodine
6 Benefits of Breast MRI for Predicting of Histopathologic Cell Type of Small Breast Cancer Unknown status NCT01597999 Phase 4
7 Assessment of Quality of Life, Bone Density and Safety in Postmenopausal Breast Cancer Patients With Letrozole Therapy Unknown status NCT00913016 Phase 4
8 Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients Unknown status NCT00912938 Phase 4 zoledronic acid
9 Study the Role of Positron Emission Mammography in Pre-surgical Planning for Breast Cancer Unknown status NCT00484614 Phase 4
10 Circulating miRNAs as Biomarkers of Hormone Sensitivity in Breast Cancer Unknown status NCT01612871 Phase 4 Tamoxifen, Letrozole , Anastrozole, Exemestane
11 A Study of Patients With HER2 Gene Amplified Metastatic Breast Cancer Treated With First Line Herceptin and a Taxane Unknown status NCT00097487 Phase 4
12 STARS Breast Trial (Study of Anastrozole and Radiotherapy Sequencing Pilot) Unknown status NCT00126360 Phase 4 Timing of Anastrozole in respect to radiotherapy
13 The MONET - Study: MR Mammography of Nonpalpable Breast Tumors Unknown status NCT00302120 Phase 4
14 Clinical Trial Comparing Outcomes of Breast Conserving Operations With Classic v High-frequency Electrocoagulation Unknown status NCT01216254 Phase 4
15 Yunzhi as Dietary Supplement in Breast Cancer Unknown status NCT00647075 Phase 4
16 Pharmacogenetics as a Predictor of Toxicity in Pre-Menopausal Women Receiving Doxorubicin and Cyclophosphamide in Early Breast Cancer Unknown status NCT00352872 Phase 4
17 Paclitaxel in Combination With Carboplatin Versus Paclitaxel Plus Epirubicin in Metastatic Breast Cancer Unknown status NCT02207361 Phase 4 Paclitaxel, Carboplatin;Paclitaxel, Epirubicin
18 Study of the Effect of Glutamine Supplementation on Chemotherapy Induced Toxicities in Breast Cancer Patients Unknown status NCT00772824 Phase 4
19 A Study of Liposomal Doxorubicin in Women With Breast Cancer Exploiting Tissue Doppler Imaging Unknown status NCT00531973 Phase 4 liposomal doxorubicin;epirubicin
20 Weekly and Every 3 Week Administration of Paclitaxel Liposome Injection in Metastatic Breast Cancer Unknown status NCT02142790 Phase 4 paclitaxel liposome injection
21 Omega-3 Fatty Acids and Chemotherapy-induced Neuropathy and Inflammation in Breast Cancer Unknown status NCT01049295 Phase 4
22 Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma Unknown status NCT00307606 Phase 4 Solu-medrol 125 mg
23 Filgrastim or Pegfilgrastim in Preventing Neutropenia in Women Receiving Chemotherapy Following Surgery for Breast Cancer Unknown status NCT00030758 Phase 4
24 Serratus Anterior Plane Block Versus Paravertebral Block for Postmastectomy Analgesia Unknown status NCT02103946 Phase 4
25 Effects of Tamoxifen in Premenopausal Women With Benign Breast Disease Not at High-Risk of Developing Breast Cancer Completed NCT00999921 Phase 4 Tamoxifen;Evening Primrose Oil
26 Single-shot Pectoral Plane(PECs) Block Versus Continuous Local Anaesthetic Infusion Analgesia or Both PECS Block and Local Anaesthetic Infusion After Breast Surgery: A Prospective Randomised, Double-blind Trial Completed NCT03024697 Phase 4
27 An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis Completed NCT01743560 Phase 4 RAD001;Exemestane
28 Eribulin Mesylate Phase IV Clinical Trial in Korean Patients With Metastatic or Locally Advanced Breast Cancer Completed NCT01961544 Phase 4 Eribulin mesylate
29 A Study of Xeloda (Capecitabine) in Women With HER2-Negative Metastatic Breast Cancer Completed NCT00121836 Phase 4 Capecitabine;Bevacizumab
30 Arthralgia During Anastrozole Therapy for Breast Cancer Completed NCT00323479 Phase 4 Anastrozole
31 A Study of Avastin With Taxane Therapy in Patients With Triple Negative Breast Cancer Completed NCT01094184 Phase 4 bevacizumab [Avastin]
32 Liver Safety Under Upfront Arimidex vs Tamoxifen Completed NCT00537771 Phase 4 Anastrozole;Tamoxifen
33 Maintenance Treatment With Liposomal Doxorubicin (Caelyx) in Metastatic Breast Cancer Patients Completed NCT00128778 Phase 4 Pegylated liposomal doxorubicin (Caelyx)
34 A Study of Herceptin (Trastuzumab) in Combination With a Taxane in Participants With HER2-Positive Breast Cancer Who Relapsed After (Neo)Adjuvant Herceptin Treatment Completed NCT01301729 Phase 4 Docetaxel;Paclitaxel;Trastuzumab
35 Wellbutrin XL, Major Depressive Disorder and Breast Cancer Completed NCT00234195 Phase 4 bupropion extended release (Wellbutrin XL)
36 Life Quality and Mental State in Patients With Breast Cancer Completed NCT01458457 Phase 4
37 Study Comparing Full-dose Radiotherapy Versus Reduced Dose in the Management of Bone Metastasis in Patients With Breast Cancer Receiving Zoledronic Acid Completed NCT00172029 Phase 4 Zoledronic acid
38 Accelerated Radiotherapy Outcomes in Women Completed NCT00156130 Phase 4
39 XeNA Study - A Study of Xeloda (Capecitabine) in Patients With Invasive Breast Cancer Completed NCT00127933 Phase 4 capecitabine [Xeloda];Taxotere;Herceptin (HER2-neu positive patients only);capecitabine [Xeloda];Taxotere
40 Safety and Efficacy of RAD001 (Everolimus) in Combination With Letrozole in the Treatment of Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer Completed NCT01231659 Phase 4 Everolimus + Letrozole
41 Breast Reconstruction With Acellular Dermal Matrix in the Setting of Breast Cancer Treatment Completed NCT02061527 Phase 4
42 Case-Control-Study on the Breast Cancer Risk of Mirena® Compared With Copper IUDs Completed NCT00461253 Phase 4
43 Will Preoperative MRI Breast in Women Under 56 Years With Breast Cancer Change Primary Treatment Completed NCT01859936 Phase 4
44 Use of the Contura™ Catheter to Deliver Accelerated Partial Breast Irradiation to "Low-risk" Breast Cancer Patients Completed NCT00882596 Phase 4
45 Comparative Efficiency of Three Regimen, CEFci, CEF and EC as Neoadjuvant Chemotherapy for Primary Breast Cancer Completed NCT01199432 Phase 4 5-FU(intravenous infusion)+epirubicin+cyclophosphamide;5-FU(intravenous bolus)+epirubicin+cyclophosphamide;epirubicin+cyclophosphamide
46 Randomized Trial of Follow-up Strategies in Breast Cancer Completed NCT00156039 Phase 4
47 Research Of Quality Of Life And Safety Outcomes Of Postmenopausal Breast Cancer Patients Switching From Tamoxifen Therapy To Aromatase Inhibitor Therapy Completed NCT00784888 Phase 4
48 Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy Completed NCT01817374 Phase 4 Definity (Perflutren Lipid Microspheres)
49 Open Label Study of Postmenopausal Women With ER and /or PgR Positive Breast Cancer Treated With Letrozole Completed NCT00237224 Phase 4 Letrozole
50 Wound Infiltration and Breast Cancer Surgery Completed NCT01404377 Phase 4

Search NIH Clinical Center for Breast Disease

Cochrane evidence based reviews: breast diseases

Genetic Tests for Breast Disease

Genetic tests related to Breast Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Breast 29

Anatomical Context for Breast Disease

MalaCards organs/tissues related to Breast Disease:

39
Breast, Bone, Lymph Node, Brain, Testes, Lung, Prostate

Publications for Breast Disease

Articles related to Breast Disease:

(show top 50) (show all 594)
id Title Authors Year
1
Evidence and role of phlebitis and lipid infiltration in the onset and pathogenesis of Wooden Breast Disease in modern broiler chickens. ( 28609139 )
2017
2
Cumulative risk of breast cancer screening outcomes according to the presence of previous benign breast disease and family history of breast cancer: supporting personalised screening. ( 28427083 )
2017
3
Cowden Syndrome: Serendipitous Diagnosis in Patients with Significant Breast Disease. Case Series and Literature Review. ( 27886412 )
2017
4
A prospective study of breast anthropomorphic measurements, volume and ptosis in 605 Asian patients with breast cancer or benign breast disease. ( 28192525 )
2017
5
Refining Risk Assessment in Women With Benign Breast Disease: An Ongoing Dilemma. ( 28376199 )
2017
6
Breast Disease Treatment in a US Military Hospital in Afghanistan. ( 27696612 )
2017
7
Benign breast disease and risk of thyroid cancer. ( 28681104 )
2017
8
Body size from birth through adolescence in relation to risk of benign breast disease in young women. ( 28062981 )
2017
9
Mammographic breast density and risk of breast cancer in women with atypical hyperplasia: an observational cohort study from the Mayo Clinic Benign Breast Disease (BBD) cohort. ( 28143431 )
2017
10
Cavernous sinus syndrome as the first manifestation of metastatic breast disease. ( 28480103 )
2017
11
Metabolic Response to Omega-3 Fatty Acids and Vitamin E Co-Supplementation in Patients with Fibrocystic Breast Disease: A Randomized, Double-Blind, Placebo-Controlled Trial. ( 28846009 )
2017
12
Diabetic Mastopathy: A Systematic Review of Surgical Management of a Rare Breast Disease. ( 28272124 )
2017
13
The Spectrum of Triple-Negative Breast Disease: High- and Low-Grade Lesions. ( 28736315 )
2017
14
Association between lifestyle, menstrual/reproductive history, and histological factors and risk of breast cancer in women biopsied for benign breast disease. ( 28643020 )
2017
15
Breast disease in men in metropolitan SALo Paulo - Brazil. ( 28741872 )
2017
16
Down-regulation of hK7 in the sera of breast cancer and benign breast disease patients. ( 28761938 )
2017
17
Plasma carotenoids and the risk of premalignant breast disease in women aged 50 and younger: a nested case-control study. ( 28190250 )
2017
18
Society of Surgical Oncology Breast Disease Working Group Statement on Prophylactic (Risk-Reducing) Mastectomy. ( 27933411 )
2017
19
Breast cancer screening: updated recommendations of the Brazilian College of Radiology and Diagnostic Imaging, Brazilian Breast Disease Society, and Brazilian Federation of Gynecological and Obstetrical Associations. ( 28894332 )
2017
20
Difference in fatty acids composition of breast adipose tissue in women with breast cancer and benign breast disease. ( 28000465 )
2016
21
Association Between Benign Breast Disease in African American and White American Women and Subsequent Triple-Negative Breast Cancer. ( 28006062 )
2016
22
Assessing the Relationship of Mammographic Breast Density and Proliferative Breast Disease. ( 27261096 )
2016
23
Phyllodes Tumor of the Breast: 307 Treated Cases, the Largest Mexican Experience at a Single Breast Disease Institution. ( 28855932 )
2016
24
A prospective study of endometriosis and risk of benign breast disease. ( 27604359 )
2016
25
Benign and Malignant Breast Disease at Rwanda's First Public Cancer Referral Center. ( 27009935 )
2016
26
Lower Serum Levels of Uric Acid in Uterine Fibroids and Fibrocystic Breast Disease Patients in Dongying City, China. ( 27398332 )
2016
27
Breast Disease. Management and Therapies. ( 27466592 )
2016
28
Downregulation of GLUT4 contributes to effective intervention of estrogen receptor-negative/HER2-overexpressing early stage breast disease progression by lapatinib. ( 27293993 )
2016
29
Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease. ( 26893016 )
2016
30
Standardized measures of lobular involution and subsequent breast cancer risk among women with benign breast disease: a nested case-control study. ( 27488681 )
2016
31
The United States' national accreditation program for breast centers: a model for excellence in breast disease evaluation and management. ( 27157999 )
2016
32
Inflammatory breast disease: A pictorial essay with radiological-pathological correlation. ( 27324090 )
2016
33
Prenatal factors and infant feeding in relation to risk of benign breast disease in young women. ( 26582399 )
2015
34
Agreement between hopelessness/helplessness and montgomery-asberg depression rating scale in healthy individuals and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland. ( 25862881 )
2015
35
Relationship between elasticity and collagen fiber content in breast disease: a preliminary report. ( 25465961 )
2015
36
The relation of hopelessness/helplessness versus beck depression inventory (BDI) in healthy individuals and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland. ( 25667478 )
2015
37
Ki-67 expression in sclerosing adenosis and adjacent normal breast terminal ductal lobular units: a nested case-control study from the Mayo Benign Breast Disease Cohort. ( 25863475 )
2015
38
Breast cancer risk associated with benign breast disease: systematic review and meta-analysis. ( 25636589 )
2015
39
Clinicopathologic features of breast cancers that develop in women with previous benign breast disease. ( 26512815 )
2015
40
Is the Benign Breast Disease Breast Cancer Model Well Calibrated? ( 26215936 )
2015
41
Inflammatory breast disease: The radiologist's role. ( 26372222 )
2015
42
Adolescent dietary vitamin D and sun exposure in relation to benign breast disease. ( 26084210 )
2015
43
Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: a study from a population-based screening program. ( 25503778 )
2015
44
Correlation of serum toll like receptor 9 and trace elements with lipid peroxidation in the patients of breast diseases. ( 25744504 )
2015
45
The prevalence of benign breast diseases in patients with nodular goiter and Hashimoto's thyroiditis. ( 25827711 )
2015
46
Emotional personality/proximity versus emotional authenticity in patient-physician communication in healthy study participants, and in patients with benign breast disease, and breast cancer: a prospective case-control study in Finland. ( 25750320 )
2015
47
Spectrum of breast disease in an urban general surgical centre in India. ( 25881642 )
2015
48
Suicidal Ideation Versus Hopelessness/Helplessness in Healthy Individuals and in Patients with Benign Breast Disease and Breast Cancer: A Prospective Case-control Study in Finland. ( 26026123 )
2015
49
Benign breast disease and the risk of breast cancer in the next 15 years. ( 25970956 )
2015
50
Breast Density and Benign Breast Disease: Risk Assessment to Identify Women at High Risk of Breast Cancer. ( 26282663 )
2015

Variations for Breast Disease

Expression for Breast Disease

Search GEO for disease gene expression data for Breast Disease.

Pathways for Breast Disease

Pathways related to Breast Disease according to GeneCards Suite gene sharing:

(show all 25)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.05 ERBB2 IGF1 PRL PRLR RHOC STAT5A
2 12.59 ERBB2 IGF1 KLK3 STAT5A TP53
3
Show member pathways
12.3 IGF1 IGFBP3 STAT5A TP53
4
Show member pathways
12.28 ERBB2 ESR1 ESR2 IGF1 KLK3 PGR
5
Show member pathways
12.24 ERBB2 ESR1 ESR2 IGF1
6 12.07 ERBB2 ESR1 IGF1 TNF TP53
7 11.95 IGF1 PRLR STAT5A TNF
8
Show member pathways
11.95 CTSD ERBB2 ESR1 ESR2 PRL PRLR
9
Show member pathways
11.75 ESR1 ESR2 PGR
10 11.62 KRT5 PRL STAT5A TP53
11
Show member pathways
11.58 COMT CYP1A1 CYP1B1
12 11.46 CYP1A1 CYP1B1 IGF1
13 11.45 PRL PRLR STAT5A
14 11.42 CYP1A1 CYP1B1 TNF
15 11.36 CTSD ESR1 TP53
16
Show member pathways
11.34 PRL PRLR STAT5A
17
Show member pathways
11.22 COMT CYP1A1 CYP1B1
18 11.18 ESR2 PGR PRLR
19 11.14 CYP1A1 CYP1B1 ESR1 TNF
20
Show member pathways
11.13 ERBB2 ESR1 PGR PRL PRLR STAT5A
21 11.1 ESR1 ESR2 SOD2
22 10.93 IGF1 IGFBP3 KLK3
23 10.56 PRL TNF
24 10.55 CYP1A1 CYP1B1 ESR1
25 10.14 ESR1 ESR2

GO Terms for Breast Disease

Cellular components related to Breast Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.91 CTSD ESR2 IGF1 IGFBP3 KLK3 PRL
2 mitochondrion GO:0005739 9.76 COMT CYP1A1 CYP1B1 ESR2 KRT5 PGR
3 insulin-like growth factor ternary complex GO:0042567 8.96 IGF1 IGFBP3
4 insulin-like growth factor binding protein complex GO:0016942 8.62 IGF1 IGFBP3

Biological processes related to Breast Disease according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.71 IGF1 IGFBP3 KLK3 PRL
2 cellular response to organic cyclic compound GO:0071407 9.65 CYP1A1 CYP1B1 TNF
3 cell proliferation GO:0008283 9.65 CYP1A1 ERBB2 IGF1 PRL TP53
4 positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 9.51 IGF1 IGFBP3
5 steroid hormone mediated signaling pathway GO:0043401 9.5 ESR1 ESR2 PGR
6 estrogen metabolic process GO:0008210 9.49 COMT CYP1B1
7 hydrogen peroxide biosynthetic process GO:0050665 9.46 CYP1A1 SOD2
8 omega-hydroxylase P450 pathway GO:0097267 9.43 CYP1A1 CYP1B1
9 lactation GO:0007595 9.33 PRL PRLR STAT5A
10 regulation of multicellular organism growth GO:0040014 9.13 IGF1 PRL STAT5A
11 toxin metabolic process GO:0009404 9.07 CYP1B1
12 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 8.8 PRL PRLR STAT5A

Molecular functions related to Breast Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 steroid hormone receptor activity GO:0003707 9.65 ESR1 ESR2 PGR
2 core promoter sequence-specific DNA binding GO:0001046 9.63 ESR1 ESR2 TP53
3 oxygen binding GO:0019825 9.58 CYP1A1 CYP1B1 SOD2
4 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879 9.54 ESR1 ESR2 PGR
5 estrogen receptor activity GO:0030284 9.43 ESR1 ESR2
6 enzyme binding GO:0019899 9.43 CYP1A1 ESR1 ESR2 PGR SOD2 TP53
7 estrogen response element binding GO:0034056 9.32 ESR1 ESR2
8 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding GO:0038052 9.16 ESR1 ESR2
9 steroid binding GO:0005496 8.92 ESR1 ESR2 PGR SHBG
10 protein binding GO:0005515 10.19 COMT CTSD CYP1A1 ERBB2 ESR1 ESR2

Sources for Breast Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UM