Breast Fibroadenoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Aliases & Classifications for Breast Fibroadenoma

Sources:
¹¹Disease Ontology, ¹³DISEASES, ²⁷GTR, ³⁰ICD10, ³⁹MeSH, ⁴⁵NCIt, ⁵⁰Novoseek, ⁶²SNOMED-CT, ⁶⁸UMLS
See all MalaCards sources

Aliases & Descriptions for Breast Fibroadenoma:

Name: Breast Fibroadenoma ¹¹ ⁵⁰ ¹³

Fibroadenoma ¹¹ ⁵⁰ ³⁹ ⁶⁸

Fibroadenoma of Breast ¹¹ ²⁷ ⁶⁸

Juvenile Fibroadenoma of Breast ¹¹ ⁶⁸

Complex Fibroadenoma of Breast ¹¹

Juvenile Fibroadenoma ¹¹

Cellular Fibroadenoma ¹¹

Classifications:

MalaCards categories:
Global: Genetic diseases, Cancer diseases, Rare diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

ICD10: ³⁰

Neoplasms

Benign neoplasms

Benign neoplasm of breast

External Ids:

Disease Ontology¹¹ DOID:1618

ICD10³⁰ D24

SNOMED-CT⁶² 189102001, 189820007, 254845004 254847007, 269640007, 46212000, 65877006, more

MeSH³⁹ D018226

NCIt⁴⁵ C3744, C4276, C5194

UMLS⁶⁸ C0178421, C0206650, C0346158 C1333137, more

Summaries for Breast Fibroadenoma

Sources:
¹¹Disease Ontology, ³⁶MalaCards, ⁷¹Wikipedia
See all MalaCards sources

Wikipedia:⁷¹ Fibroadenomas of the breast are benign tumors characterized by an admixture of stromal and epithelial... more...

MalaCards based summary: Breast Fibroadenoma, also known as fibroadenoma, is related to breast giant fibroadenoma and multiple fibroadenomas of the breast. An important gene associated with Breast Fibroadenoma is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways are Aromatase Inhibitor Pathway (Breast Cell), Pharmacodynamics and Signaling by ERBB4. Affiliated tissues include breast, breast and lung, and related mouse phenotypes are neoplasm and digestive/alimentary.

Disease Ontology:¹¹ A breast benign neoplasm comprised of fibrous and glandoular tissues located in breast.

Related Diseases for Breast Fibroadenoma

Sources:
²⁰GeneAnalytics, ²¹GeneCards
See all MalaCards sources

Diseases in the Breast Fibroadenoma family:

Multiple Fibroadenomas of the Breast

Diseases related to Breast Fibroadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)

id	Related Disease	Score	Top Affiliating Genes
1	breast giant fibroadenoma	11.1
2	multiple fibroadenomas of the breast	11.0
3	breast pericanalicular fibroadenoma	11.0
4	mouth disease	10.3	ERBB2, PGR
5	pericardium leiomyoma	10.3	MED12, PGR
6	mucoepidermoid thyroid carcinoma	10.3	ERBB2, PGR
7	triple-receptor negative breast cancer	10.3	ERBB2, PGR
8	renal infectious disease	10.3	ERBB2, KRT8
9	skin sarcoma	10.3	ERBB2, PGR
10	bartholin's gland benign neoplasm	10.3	ESR1, PGR
11	cardiovascular organ benign neoplasm	10.3	ESR1, PGR
12	appendix leiomyoma	10.3	ESR1, PGR
13	bronchus adenoma	10.3	ESR1, PGR
14	ovarian benign neoplasm	10.3	ESR1, PGR
15	plexiform neurofibroma	10.3	ESR1, PGR
16	hereditary breast ovarian cancer	10.3	ERBB2, ESR1
17	paranasal sinus disease	10.3	ESR1, PGR
18	deafness, autosomal recessive 21	10.3	ESR1, PGR
19	atypical lipomatous tumor	10.3	ESR1, PGR
20	congenital disorder of glycosylation, type ic	10.2	ESR1, PGR
21	intestinal perforation	10.2	ESR1, PGR
22	perlman syndrome	10.2	ESR1, PGR
23	biemond syndrome	10.2	CYP19A1, PGR
24	bladder adenocarcinoma	10.2	ESR1, PGR
25	glioma	10.2	ERBB2, ESR1, PGR
26	cervical lymphoepithelioma-like carcinoma	10.2	ERBB2, ESR1, PGR
27	histiocytic and dendritic cell cancer	10.2	ERBB2, ESR1, PGR
28	poliomyelitis	10.2	ERBB2, ESR1, PGR
29	anal neuroendocrine tumor	10.2	ESR1, PGR
30	central nervous system mature teratoma	10.2	ERBB2, ESR1, PGR
31	postpartum depression	10.2	ERBB2, ESR1, PGR
32	combined t cell and b cell immunodeficiency	10.2	ERBB2, ESR1, PGR
33	anomalous left coronary artery from the pulmonary artery	10.2	ERBB2, ESR1, PGR
34	polyembryoma of the ovary	10.2	ERBB2, ESR1, PGR
35	fallopian tube carcinosarcoma	10.2	ERBB2, ESR1, PGR
36	sclerosing hemangioma	10.2	ERBB2, ESR1, PGR
37	osteogenesis imperfecta	10.2	CYP19A1, ESR1, PGR
38	organ system benign neoplasm	10.2	ERBB2, ESR1, PGR
39	his bundle tachycardia	10.2	ERBB2, ESR1, PGR
40	lung squamous cell carcinoma	10.2	KRT15, KRT8
41	her2-receptor positive breast cancer	10.2	ERBB2, ESR1, PGR
42	acute thyroiditis	10.2	CYP19A1, ESR1, PGR
43	perinatal jaundice due to hepatocellular damage	10.2	CYP19A1, ESR1, PGR
44	congenital bile acid synthesis defect	10.2	ERBB2, ESR1, PGR
45	epithelioid neurofibroma	10.2	ESR1, MED12, PGR
46	esophagus sarcoma	10.2	CYP19A1, ESR1, PGR
47	pyomyositis	10.2	ERBB2, ESR1, PGR
48	metagonimiasis	10.2	ERBB2, ESR1, PGR
49	pituitary stalk meningioma	10.2	ERBB2, ESR1, PGR
50	prostatic adenoma	10.2	ERBB2, ESR1, PGR

Graphical network of the top 20 diseases related to Breast Fibroadenoma:

Symptoms & Phenotypes for Breast Fibroadenoma

Sources:
⁴¹MGI
See all MalaCards sources

MGI Mouse Phenotypes related to Breast Fibroadenoma according to GeneCards Suite gene sharing:

⁴¹

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	neoplasm	MP:0002006	8.9	ERBB2, ESR1, KRT14, NME1, PGR, RASSF1
2	digestive/alimentary	MP:0005381	8.7	CYP19A1, ERBB2, ESR1, KRT14, KRT8, NGFR
3	endocrine/exocrine gland	MP:0005379	8.7	CYP19A1, ERBB2, ESR1, KRT14, NME1, PGR
4	cardiovascular system	MP:0005385	8.7	CYP19A1, ERBB2, ESR1, KRT8, MED12, NGFR
5	normal	MP:0002873	8.2	CYP19A1, ERBB2, ESR1, MED12, NGFR, PGR
6	liver/biliary system	MP:0005370	7.9	CYP19A1, ESR1, KRT8, MME, NGFR, NME1
7	integument	MP:0010771	7.8	CYP19A1, ERBB2, ESR1, KRT14, MME, NGFR

Drugs & Therapeutics for Breast Fibroadenoma

Sources:
¹BitterDB, ⁴ClinicalTrials, ⁷Cochrane Library, ¹⁰DGIdb, ¹⁴DrugBank, ²⁹HMDB, ³³IUPHAR, ⁴⁶NDF-RT, ⁵⁰Novoseek, ⁵⁶PharmGKB, ⁶⁸UMLS
See all MalaCards sources

Drugs for Breast Fibroadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)

id

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Tamoxifen

approved

Phase 4

390

10540-29-1

2733526

Synonyms:

(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene

(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine

(Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine

(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine

(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC)

(Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE

(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine

,citrate

1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

1-p-.beta.-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene

1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene

10540-29-1

1ya4

2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine

2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine

54965-24-1 (citrate)

AC1MBZ3R

Apo-Tamox

Apo-tamox

BIDD:ER0008

BIDD:GT0009

BIDD:PXR0003

BPBio1_000278

BRD-K93754473-001-02-9

BRD-K93754473-048-05-3

BSPBio_000252

BSPBio_001150

BSPBio_001982

C07108

C26H29NO

CCRIS 3275

CHEBI:41774

CHEMBL83

CID2733526

Citofen

Crisafeno

D08559

DB00675

Diemon

EINECS 234-118-0

Gen-Tamoxifen

Gen-tamoxifen

HMS1362J11

HMS1792J11

HMS1990J11

HMS2090N08

HSDB 6782

ICI 47699

ICI-46,474

ICI-47699

IDI1_000258

IDI1_002170

Istubol

Kessar

L024126

LS-393

Lopac0_001203

MLS001332535

MLS001332536

MolPort-003-850-384

NCGC00024928-01

NCGC00024928-03

NCGC00024928-04

NCGC00024928-05

NCGC00024928-07

NCGC00024928-08

NCGC00024928-09

NCGC00024928-12

NSC727681

Noltam

Nolvadex

Nolvadex-D

Nourytam

Novaldex

Novo-Tamoxifen

Oncomox

PMS-Tamoxifen

Pms-Tamoxifen

Prestwick2_000146

Prestwick3_000146

QTL1_000079

Retaxim

SMR000059172

ST50511785

Spectrum5_001417

Spectrum5_002043

T5648_SIGMA

TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1))

TRANS FORM OF TAMOXIFEN

Tamizam

Tamofen

Tamone

Tamoplex (TN)

Tamoxasta

Tamoxen

Tamoxifen

Tamoxifen (INN)

Tamoxifen (TN)

Tamoxifen (Z)

Tamoxifen Citrate

Tamoxifen [INN:BAN]

Tamoxifen and its salts

Tamoxifene

Tamoxifene [INN-French]

Tamoxifeno

Tamoxifeno [INN-Spanish]

Tamoxifenum

Tamoxifenum [INN-Latin]

Tamoxifène

Tocris-0999

Tomaxithen

Trans-Tamoxifen

UNII-094ZI81Y45

UPCMLD-DP027

Valodex

Zemide

cMAP_000044

nchembio.140-comp7

nchembio.76-comp1

nchembio732-comp3

tamoxifen

trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine

trans-Tamoxifen

2

Hormones

Phase 4

14415

3

Hormone Antagonists

Phase 4

13180

4

Analgesics

Phase 4

11733

5

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4

13168

6

Lipid Regulating Agents

Phase 4

2766

7

Selective Estrogen Receptor Modulators

Phase 4

601

8

Peripheral Nervous System Agents

Phase 4

23689

9

Estrogen Receptor Modulators

Phase 4

645

10

Hypolipidemic Agents

Phase 4

2785

11

Estrogens

Phase 4

2542

12

Estrogen Antagonists

Phase 4

1349

13

Anti-Inflammatory Agents, Non-Steroidal

Phase 4

4443

14

Anti-Inflammatory Agents

Phase 4

10729

15

Analgesics, Non-Narcotic

Phase 4

6501

16

Antineoplastic Agents, Hormonal

Phase 4

5592

17

Antimetabolites

Phase 4

12054

18

Antirheumatic Agents

Phase 4

10956

19

Dermatologic Agents

Phase 4

5806

20

Efamol

Phase 4

17

21

Bone Density Conservation Agents

Phase 4

3376

22

Evening Primrose

Nutraceutical

Phase 4

6

23

Pharmaceutical Solutions

8192

24

Immunoglobulins

6394

25

Autoantibodies

130

26

Antibodies

6394

Interventional clinical trials:

(show all 17)

id	Name	Status	NCT ID	Phase
1	Effects of Tamoxifen in Premenopausal Women With Benign Breast Disease Not at High-Risk of Developing Breast Cancer	Completed	NCT00999921	Phase 4
2	Feasibility Study Assessing the Treatment of Fibroadenomata With a Circumferential Sonication Treatment With HIFU	Active, not recruiting	NCT02139683	Phase 3
3	Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)	Active, not recruiting	NCT02011919	Phase 2, Phase 3
4	MR Guided Focused Ultrasound Surgery in the Treatment of Breast Fibroadenomas	Terminated	NCT00147108	Phase 3
5	High Intensity Focused Ultrasound (HIFU) to Treat Breast Fibroadenoma	Completed	NCT01422629
6	Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)	Completed	NCT03022695
7	ICE-SENSE™ Cryotherapy for Breast Fibroadenoma Trial	Completed	NCT00910312
8	Optical Tomography With Ultrasound Guidance	Completed	NCT00908609
9	Treatment of Breast Fibroadenoma Targeted Tissue With HIFU	Recruiting	NCT03044054
10	Treatment of Breast Fibroadenoma With FastScan HIFU	Recruiting	NCT02488655
11	American Breast Laser Ablation Therapy Evaluation	Recruiting	NCT00807924
12	Evaluation of Virtual Touch Tissue Imaging Quantification (VTIQ - 2D-SWE) in the Assessment of BI-RADS® 3 and 4 Lesions	Recruiting	NCT02638935
13	Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound	Active, not recruiting	NCT02078011
14	Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)	Active, not recruiting	NCT01331954
15	LOUIS-3D Breast Study	Active, not recruiting	NCT01755130
16	Synthetic Aperture Radar Detection of Breast Tumours	Enrolling by invitation	NCT02493595
17	Blood Test for Breast Cancer Associated Auto Antibodies - Improvement of Octava Blood Test	Not yet recruiting	NCT02066025

Search NIH Clinical Center for Breast Fibroadenoma

Cochrane evidence based reviews: fibroadenoma

Genetic Tests for Breast Fibroadenoma

Sources:
²⁷GTR
See all MalaCards sources

Genetic tests related to Breast Fibroadenoma:

id	Genetic test	Affiliating Genes
1	Fibroadenoma of the Breast²⁷

Anatomical Context for Breast Fibroadenoma

Sources:
¹⁷FMA, ³⁶MalaCards
See all MalaCards sources

MalaCards organs/tissues related to Breast Fibroadenoma:

³⁶

Breast, Lung

FMA organs/tissues related to Breast Fibroadenoma:

¹⁷

Breast

Publications for Breast Fibroadenoma

Sources:
⁵⁷PubMed
See all MalaCards sources

Articles related to Breast Fibroadenoma:

(show top 50) (show all 59)

id	Title	Authors	Year
1	Breast Fibroadenoma With Increased Activity on 68Ga DOTATATE PET/CT. (27879489)	Papadakis G.Z.... Patronas N.J.	2017
2	Primary Infarction of Breast Fibroadenoma in the Absence of Pregnancy or Lactation. (27670396)	Agorogiannis E.... Metaxas G.	2017
3	Invasive Ductal Carcinoma Displayed "Basal-Like" Feature Arising within a Breast Fibroadenoma. (27870335)	Ma X.L.... Zhao H.F.	2016
4	Multimodality approach in the diagnosis and management of bilateral giant juvenile breast fibroadenoma. (27758851)	Rafeek N.... Joseph S.	2016
5	Ultrasound-guided high-intensity focused ultrasound treatment of breast fibroadenoma-a multicenter experience. (25635224)	Kovatcheva R.... Poncelet E.	2015
6	Ultrasound-guided cryoablation of breast fibroadenoma: a pilot trial. (25408274)	Golatta M.... Hahn M.	2014
7	High resolution compression elastography and color doppler sonography in characterization of breast fibroadenoma. (25227197)	Rjosk-Dendorfer D.... Clevert D.A.	2014
8	Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma. (25038752)	Lim W.K.... Teh B.T.	2014
9	Fine-needle aspiration of gray zone lesions of the breast: fibroadenoma versus ductal carcinoma. (22936545)	Jing X.... Michael C.W.	2013
10	Lobular intraepithelial neoplasia arising within breast fibroadenoma. (23849288)	Limite G.... Forestieri P.	2013
11	First case of transformation for breast fibroadenoma to high-grade malignant phyllodes tumor in an in vitro fertilization patient: misdiagnosis of recurrence, treatment and review of the literature. (24089229)	Pacchiarotti A.... Frati P.	2013
12	Transaxillary approach with use of traction suture for excision of breast fibroadenoma: a new technique and its results. (22604577)	Khan P.S.... Hayat G.	2012
13	Fibroadenoma of the vulva--simultaneous with breast fibroadenomas and uterine myoma. (21192183)	Audisio T.... Ramallo R.	2011
14	Aberrant DNA methylation of cancer-related genes in giant breast fibroadenoma: a case report. (22011321)	Marzese D.M.... Vargas-Roig L.M.	2011
15	Prepubertal vulval fibroma with a coincidental ectopic breast fibroadenoma: report of an unusual case with literature review. (21733035)	Zhang J.... Liu H.	2011
16	A clinical study on the resection of breast fibroadenoma using two types of incision. (22108740)	Liu X.F.... Lu C.	2011
17	First case of transformation for breast fibroadenoma toA high-grade malignant cystosarcoma in an inA vitro fertilization patient. (21917252)	Pacchiarotti A.... Moscarini M.	2011
18	Role of exogenous and endogenous sources of estrogen on the incidence of breast fibroadenoma: case-control study in Iran. (21875284)	Bidgoli S.A.... Eftekhari T.	2011
19	Analysis of CD83 antigen expression in human breast fibroadenoma and adjacent tissue. (22249796)	Borges M.N.... Nazario A.C.	2011
20	Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumors. (22121516)	Abe M.... Iwase T.	2011
21	Vacuum-assisted core-needle biopsy as a diagnostic and therapeutic method in lesions radiologically suspicious of breast fibroadenoma. (24376952)	PoA8om K.... Murawa P.	2010
22	Comparison of telomere length and telomerase activation between breast fibroadenoma and infiltrating ductal carcinoma in Malaysian women. (21039041)	Looi L.M.... Rahman N.A.	2010
23	Characterization of two constitutively active prolactin receptor variants in a cohort of 95 women with multiple breast fibroadenomas. (19897676)	Courtillot C.... Touraine P.	2010
24	Ectopic breast fibroadenoma of the vulva. (19622961)	Lucas E.W.... Moawad G.N.	2009
25	Herb-related aneuploidy in breast fibroadenoma. (21686556)	Chang C.J.... Lui W.Y.	2009
26	A breast fibroadenoma mimicking an extranodal deposit of Hodgkin's lymphoma in 67Ga imaging. (19211906)	Moralidis E.... Karakatsanis C.	2009
27	Recurrence of giant juvenile breast fibroadenoma in a girl with Turner's syndrome. (19492586)	Calcaterra V.... Larizza D.	2009
28	Human epithelial growth factor receptor 2[Ile655Val] polymorphism and risk of breast fibroadenoma. (18090908)	Zubor P.... Danko J.	2008
29	Invasive mucinous carcinoma arising within breast fibroadenoma. (18841829)	Charfi L.... Ben Romdhane K.	2008
30	Breast fibroadenoma in female adolescents. (17206308)	Tiryaki T.... Kibar A.E.	2007
31	Effect of oral contraceptive with and without associated estriol on ultrasound measurements of breast fibroadenoma: randomized clinical trial. (18094894)	EstevALo R.A.... Baracat E.C.	2007
32	FNA of breast fibroadenoma: observer variability and review of cytomorphology with cytohistological correlation. (16961651)	Kollur S.M.... el Hag I.A.	2006
33	Characteristic features of function of morphofunctional zones in normal epithelium, breast fibroadenoma, and breast cancer. (16405127)	Yavisheva T.M.... Savluchinskaya L.A.	2005
34	Malignant transformation of a breast fibroadenoma to cystosarcoma phyllodes: case report and review of the literature. (15943412)	Valdes E.K.... Feldman S.M.	2005
35	Magnetic resonance imaging findings in an axillary accessory breast fibroadenoma. (16297109)	Yuen S.... Furukawa H.	2005
36	p16(INK4a) promoter methylation and protein expression in breast fibroadenoma and carcinoma. (15578730)	di Vinci A.... Romani M.	2005
37	Progressive adoption of cryoablative therapy for breast fibroadenoma in community practice. (15450823)	Edwards M.J.... Oetting L.	2004
38	Breast fibroadenoma in teenage females. (14768798)	Onuigbo W.	2003
39	Breast fibroadenoma in a male-to-female transsexual patient after hormonal treatment. (15200048)	Lemmo G.... Garcea R.	2003
40	Expression of acidic fibroblast growth factor (aFGF) and fibroblast growth factor receptor 4 (FGFR4) in breast fibroadenomas. (11271786)	La Rosa S.... Capella C.	2001
41	Fine needle aspiration diagnosis of a breast fibroadenoma with multinucleated stromal giant cells. (10349403)	Lanjewar D.N.... Bhosale A.S.	1999
42	Breast fibroadenoma: mapping of pathophysiologic features with three-time-point, contrast-enhanced MR imaging--pilot study. (9885614)	Weinstein D.... Degani H.	1999
43	Fine needle aspiration cytology of breast fibroadenoma. A cytohistologic correlation study of 405 cases. (10432878)	LA^pez-Ferrer P.... Viguer J.M.	1999
44	Diagnostic value of fine needle aspiration biopsy for breast fibroadenoma diagnosis. (9278103)	Szylberg T.... Kulig A.	1997
45	Concentrations of estrone, estradiol and their sulfates, and evaluation of sulfatase and aromatase activities in patients with breast fibroadenoma. (9096642)	Pasqualini J.R.... Ruiz A.	1997
46	Breast fibroadenoma with atypical features: a case report. (8629423)	Kordek R.... Kubiak R.	1996
47	Infarction of breast fibroadenoma in a postmenopausal woman. (8044310)	Ichihara S.... Aoyama H.	1994
48	Aspiration cytology of breast fibroadenoma with atypia. (1606889)	Chen K.T.	1992
49	Possibilities of the conventional and interventional sonography in diagnosis of breast fibroadenoma. (1841055)	Nedeva A.... Ivanov V.	1991
50	Medulloblastoma metastasizing to a breast fibroadenoma: a case report. (2021436)	Brydon H.L.... Carey M.P.	1991

Genes related to Breast Fibroadenoma

Sources:
⁸Cosmic, ¹³DISEASES, ²¹GeneCards, ⁵⁰Novoseek
See all MalaCards sources

Genes related to Breast Fibroadenoma:

(show all 14)

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication	PubmedIds
1	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	40.39	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders, Publications (show sections)	7911069, 8687126, 18390199 more 1672262, 10541479, 19008567, 7687354, 9228249, 9513721, 15646810
2	PGR	Progesterone Receptor	32.80	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	2174150, 12602927, 17845825 more 8951485
3	MED12	Mediator Complex Subunit 12	32.38	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications (show sections)
4	ESR1	Estrogen Receptor 1	31.70	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	19367380, 15763593, 9346175 more 11378342, 16554735, 17845825, 12699101, 12846865, 12895350, 18227734
5	CYP19A1	Cytochrome P450 Family 19 Subfamily A Member 1	30.72	DISEASES inferred ¹³ GeneCards inferred via : Disorders, Publications (show sections)
6	KRT15	Keratin 15	29.61	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	9150945, 8932346
7	KRT8	Keratin 8	28.28	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	14660278, 16825119, 9150945 more 8932346
8	HMGA2	High Mobility Group AT-Hook 2	28.11	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	8739083, 8908160, 16885341 more 9495195
9	RASSF1	Ras Association Domain Family Member 1	27.75	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	15942659, 15251963
10	KRT14	Keratin 14	27.36	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	1708927
11	ARSH	Arylsulfatase Family Member H	27.34	GeneCards inferred via : Disorders, Publications (show sections)
12	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	26.72	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	17642161
13	MME	Membrane Metalloendopeptidase	25.67	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	1708927
14	NGFR	Nerve Growth Factor Receptor	24.68	DISEASES inferred ¹³ Novoseek inferred ⁵⁰ GeneCards inferred via : Disorders (show sections)	16258511, 1708927

Variations for Breast Fibroadenoma

Expression for genes affiliated with Breast Fibroadenoma

Sources:
¹⁸Gene Expression Omnibus DataSets
See all MalaCards sources

Search GEO for disease gene expression data for Breast Fibroadenoma.

Pathways for genes affiliated with Breast Fibroadenoma

Sources:
⁴²NCBI BioSystems Database, ⁵⁵PathCards, ⁵⁶PharmGKB, ⁶⁰Reactome
See all MalaCards sources

Pathways related to Breast Fibroadenoma according to GeneCards Suite gene sharing:

id	Super pathways	Score	Top Affiliating Genes
1	Aromatase Inhibitor Pathway (Breast Cell), Pharmacodynamics⁵⁶	9.9	CYP19A1, ESR1
2	Signaling by ERBB4⁶⁰ Show member pathways ErbB4 signaling events⁴² Nuclear signaling by ERBB4⁶⁰ Downregulation of ERBB4 signaling⁶⁰	9.7	ERBB2, ESR1, PGR

GO Terms for genes affiliated with Breast Fibroadenoma

Sources:
¹⁹Gene Ontology
See all MalaCards sources

Cellular components related to Breast Fibroadenoma according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	intermediate filament	GO:0005882	9.5	KRT14, KRT15, KRT8, NME1
2	nucleus	GO:0005634	6.4	ERBB2, ESR1, HMGA2, KRT14, KRT15, KRT8

Biological processes related to Breast Fibroadenoma according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	androgen metabolic process	GO:0008209	10.5	CYP19A1, ESR1
2	intracellular steroid hormone receptor signaling pathway	GO:0030518	10.5	ESR1, MED12
3	transcription initiation from RNA polymerase II promoter	GO:0006367	10.0	ESR1, MED12, PGR
4	cornification	GO:0070268	9.9	KRT14, KRT15, KRT8
5	uterus development	GO:0060065	9.9	CYP19A1, ESR1