MCID: BRS015
MIFTS: 27

Breast Medullary Carcinoma malady

Immune diseases, Cancer diseases categories

Summaries for Breast Medullary Carcinoma

About this section


MalaCards based summary: Breast Medullary Carcinoma, also known as medullary breast carcinoma with lymphoid stroma, is related to goblet cell carcinoid and tubular adenocarcinoma. An important gene associated with Breast Medullary Carcinoma is CDH1 (cadherin 1, type 1, E-cadherin (epithelial)), and among its related pathways are Integrated Breast Cancer Pathway and Hippo signaling pathway. The compounds chlorophyllin and cyclopamine have been mentioned in the context of this disorder. Affiliated tissues include breast.

Aliases & Classifications for Breast Medullary Carcinoma

About this section

Breast Medullary Carcinoma, Aliases & Descriptions:

Name: Breast Medullary Carcinoma 9
Medullary Breast Carcinoma with Lymphoid Stroma 9
 
Medullary Carcinoma of Breast 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Immune diseases


External Ids:

Disease Ontology9 DOID:5605
NCIt38 C9119

Related Diseases for Breast Medullary Carcinoma

About this section

Graphical network of diseases related to Breast Medullary Carcinoma:



Diseases related to breast medullary carcinoma

Symptoms for Breast Medullary Carcinoma

About this section

Drugs & Therapeutics for Breast Medullary Carcinoma

About this section

Drug clinical trials:

Search ClinicalTrials for Breast Medullary Carcinoma

Search NIH Clinical Center for Breast Medullary Carcinoma

Genetic Tests for Breast Medullary Carcinoma

About this section

Anatomical Context for Breast Medullary Carcinoma

About this section

MalaCards organs/tissues related to Breast Medullary Carcinoma:

31
Breast

Animal Models for Breast Medullary Carcinoma or affiliated genes

About this section

Publications for Breast Medullary Carcinoma

About this section

Articles related to Breast Medullary Carcinoma:

idTitleAuthorsYear
1
Immunoglobulin repertoire of B lymphocytes infiltrating breast medullary carcinoma. (15156099)
2003
2
A scFv phage display mini library generated from the immunoglobulin repertoire of breast medullary carcinoma infiltrating B lymphocytes. (11360824)
2000
3
E-cadherin and beta-catenin expression in breast medullary carcinomas. (10402239)
1999
4
Immunoglobulin variable regions usage by B-lymphocytes infiltrating a human breast medullary carcinoma. (10065736)
1999

Variations for Breast Medullary Carcinoma

About this section

Expression for genes affiliated with Breast Medullary Carcinoma

About this section
Search GEO for disease gene expression data for Breast Medullary Carcinoma.

Pathways for genes affiliated with Breast Medullary Carcinoma

About this section

Pathways related to Breast Medullary Carcinoma according to GeneCards Suite gene sharing:

(show all 35)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1CTNNB1, CDH1
29.1CTNNB1, CDH1
3
Show member pathways
Signaling Pathways in Glioblastoma36
9.1CDH1, CTNNB1
49.1CDH1, CTNNB1
5
Show member pathways
Development ERBB family signaling58
Development GDNF family signaling58
9.1CDH1, CTNNB1
6
Show member pathways
9.1CTNNB1, CDH1
79.1CDH1, CTNNB1
8
Show member pathways
Wnt Signaling Pathway NetPath36
9.1CDH1, CTNNB1
99.1CDH1, CTNNB1
10
Show member pathways
9.1CDH1, CTNNB1
11
Show member pathways
Proteasome Degradation36
Immune response Antigen presentation by MHC class I58
9.1CTNNB1, CDH1
12
Show member pathways
9.1CTNNB1, CDH1
13
Show member pathways
9.1CDH1, CTNNB1
149.1CDH1, CTNNB1
15
Show member pathways
9.1CDH1, CTNNB1
16
Show member pathways
9.1CTNNB1, CDH1
17
Show member pathways
Signal transduction PTEN pathway58
9.1CDH1, CTNNB1
18
Show member pathways
Neurophysiological process Receptor mediated axon growth repulsion58
Pathogenic Escherichia coli infection36
Cytoskeleton remodeling Slit Robo signaling
9.1CTNNB1, CDH1
199.1CTNNB1, CDH1
20
Show member pathways
9.1CTNNB1, CDH1
219.1CTNNB1, CDH1
229.1CTNNB1, CDH1
239.1CTNNB1, CDH1
249.1CTNNB1, CDH1
259.1CTNNB1, CDH1
269.1CDH1, CTNNB1
279.1CTNNB1, CDH1
289.1CDH1, CTNNB1
299.1CTNNB1, CDH1
309.1CTNNB1, CDH1
31
Show member pathways
RAC1 signaling pathway36
9.1CDH1, CTNNB1
329.1CTNNB1, CDH1
339.1CTNNB1, CDH1
349.1CDH1, CTNNB1
359.1CTNNB1, CDH1

Compounds for genes affiliated with Breast Medullary Carcinoma

About this section

Compounds related to Breast Medullary Carcinoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1chlorophyllin439.6CTNNB1, CDH1
2cyclopamine43 5910.6CTNNB1, CDH1
3exisulind439.6CTNNB1, CDH1
4sodium bisulfite439.6CDH1, CTNNB1
5etodolac43 1210.6CTNNB1, CDH1
6gamma-linolenic acid43 2410.6CTNNB1, CDH1
7dfmo43 28 5911.6CDH1, CTNNB1
8crcs439.6CTNNB1, CDH1
9indole-3-carbinol439.6CTNNB1, CDH1
10sulindac43 1210.6CDH1, CTNNB1
11methylcellulose439.6CTNNB1, CDH1
12acetaldehyde28 43 2411.6CTNNB1, CDH1
13leptomycin b43 5910.6CDH1, CTNNB1
14celecoxib43 59 28 49 24 1214.5CTNNB1, CDH1
15gefitinib43 49 1211.5CTNNB1, CDH1
16geldanamycin43 49 59 1212.5CTNNB1, CDH1
17nocodazole43 1210.5CDH1, CTNNB1
18p002439.5CTNNB1, CDH1
19mannitol43 1210.5CTNNB1, CDH1
20verapamil43 28 49 24 1213.5CDH1, CTNNB1
21adriamycin439.5CTNNB1, CDH1
22cytochalasin d43 5910.5CTNNB1, CDH1
23egcg439.5CDH1, CTNNB1
24dihydrotestosterone43 28 24 1212.5CTNNB1, CDH1
25mg 13243 5910.5CTNNB1, CDH1
26tgf beta1439.5CDH1, CTNNB1
27herbimycin a43 5910.5CTNNB1, CDH1
28curcumin439.5CTNNB1, CDH1
295-aza-2deoxycytidine439.5CDH1, CTNNB1
30sucrose43 24 1211.5CTNNB1, CDH1
31aspirin43 49 28 2412.5CTNNB1, CDH1
325fluorouracil439.5CDH1, CTNNB1
33agar439.5CTNNB1, CDH1
34retinoid439.4CTNNB1, CDH1
35matrigel439.4CDH1, CTNNB1
36phosphotyrosine439.4CTNNB1, CDH1
37n acetylcysteine439.4CTNNB1, CDH1
38sb 20358043 5910.4CDH1, CTNNB1
39butyrate439.4CTNNB1, CDH1
40tamoxifen43 49 28 1212.4CTNNB1, CDH1
41vitamin d439.4CDH1, CTNNB1
42paclitaxel43 49 1211.3CTNNB1, CDH1
43histamine43 28 2411.3CTNNB1, CDH1
44rapamycin439.3CDH1, CTNNB1
45pd 98,059439.2CTNNB1, CDH1
46ly294002439.2CTNNB1, CDH1
47wortmannin439.1CDH1, CTNNB1
48paraffin439.1CTNNB1, CDH1
49doxorubicin43 49 1211.0CTNNB1, CDH1
50glycogen43 249.8CTNNB1, CDH1

GO Terms for genes affiliated with Breast Medullary Carcinoma

About this section

Cellular components related to Breast Medullary Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1catenin complexGO:00163429.3CTNNB1, CDH1
2cell-cell adherens junctionGO:00059139.3CTNNB1, CDH1
3cytoplasmic side of plasma membraneGO:00098989.2CTNNB1, CDH1
4lateral plasma membraneGO:00163289.2CTNNB1, CDH1
5apical part of cellGO:00451779.1CDH1, CTNNB1
6perinuclear region of cytoplasmGO:00484719.1CTNNB1, CDH1
7basolateral plasma membraneGO:00163239.0CTNNB1, CDH1
8cell junctionGO:00300548.8CTNNB1, CDH1

Biological processes related to Breast Medullary Carcinoma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1cellular response to indole-3-methanolGO:00716819.3CTNNB1, CDH1
2regulation of protein localization to cell surfaceGO:020000089.2CTNNB1, CDH1
3cellular component disassembly involved in execution phase of apoptosisGO:00069219.2CTNNB1, CDH1
4cell-cell adhesionGO:00163379.1CDH1, CTNNB1
5apoptotic processGO:00069159.1CTNNB1, CDH1
6response to drugGO:00424939.0CTNNB1, CDH1
7positive regulation of transcription, DNA-templatedGO:00458938.8CTNNB1, CDH1

Molecular functions related to Breast Medullary Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein phosphatase bindingGO:00199039.1CTNNB1, CDH1

Products for genes affiliated with Breast Medullary Carcinoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Breast Medullary Carcinoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet