MCID: BRS071

Breast-Ovarian Cancer, Familial, 1 malady

Cancer, Genetic categories

Summaries for Breast-Ovarian Cancer, Familial, 1

Sources:
47OMIM, 33MalaCards
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MalaCards: Breast-Ovarian Cancer, Familial, 1 An important gene associated with Breast-Ovarian Cancer, Familial, 1 is BRCA1 (breast cancer 1, early onset). Affiliated tissues include breast.

Description from OMIM:47 604370

Aliases & Classifications for Breast-Ovarian Cancer, Familial, 1

Sources:
47OMIM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer, Genetic


Aliases & Descriptions:

breast-ovarian cancer, familial, 1 47


Related Diseases for Breast-Ovarian Cancer, Familial, 1

Clinical Features for Breast-Ovarian Cancer, Familial, 1

Sources:
47OMIM
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Clinical features from OMIM:

604370

Clinical synopsis from OMIM:

604370

Drugs & Therapeutics for Breast-Ovarian Cancer, Familial, 1

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Breast-Ovarian Cancer, Familial, 1

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Genetic Tests for Breast-Ovarian Cancer, Familial, 1

Anatomical Context for Breast-Ovarian Cancer, Familial, 1

Sources:
33MalaCards
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MalaCards organs/tissues related to Breast-Ovarian Cancer, Familial, 1:

33
Breast

Animal Models for Breast-Ovarian Cancer, Familial, 1 or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Breast-Ovarian Cancer, Familial, 1

Sources:
51PubMed
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Articles related to Breast-Ovarian Cancer, Familial, 1:

idTitleAuthorsYear
1
Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients. (20810544)
2010
2
A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. (18660546)
2008
3
Familial breast-ovarian cancer locus on chromosome 17q12-q23. (1676470)
1991

Genetic Variations for Breast-Ovarian Cancer, Familial, 1

Sources:
63UniProtKB/Swiss-Prot
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Genetic disease variations for Breast-Ovarian Cancer, Familial, 1:

63
id Symbol AA change Variation SNP ID
1BRCA1p.Glu10LysVAR_020679
2BRCA1p.Glu23LysVAR_020680
3BRCA1p.Ser1187IleVAR_020690
4BRCA1p.Gln1200HisVAR_020691rs56214134
5BRCA1p.Ser1217TyrVAR_020695
6BRCA1p.Phe1226LeuVAR_020696
7BRCA1p.Arg1243GlyVAR_020697

Expression for genes affiliated with Breast-Ovarian Cancer, Familial, 1

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Breast-Ovarian Cancer, Familial, 1

Search GEO for disease gene expression data for Breast-Ovarian Cancer, Familial, 1.

Pathways for genes affiliated with Breast-Ovarian Cancer, Familial, 1

Compounds for genes affiliated with Breast-Ovarian Cancer, Familial, 1

GO Terms for genes affiliated with Breast-Ovarian Cancer, Familial, 1

Products for genes affiliated with Breast-Ovarian Cancer, Familial, 1

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Breast-Ovarian Cancer, Familial, 1

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet