MCID: BRS061
MIFTS: 30

Breast Sarcoma malady

Cancer diseases category

Summaries for Breast Sarcoma

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32MalaCards
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MalaCards: Breast Sarcoma, also known as sarcoma of breast, is related to sarcoma and breast cancer. An important gene associated with Breast Sarcoma is TP53 (tumor protein p53), and among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. The compounds hydroxyurea and vincristine have been mentioned in the context of this disorder. Affiliated tissues include breast, myeloid and bone.

Aliases & Classifications for Breast Sarcoma

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

breast sarcoma 8
sarcoma of breast 8 60


External Ids:

Disease Ontology8 DOID:3017
SNOMED-CT56 278050001
NCIt39 C4670

Related Diseases for Breast Sarcoma

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Breast Sarcoma:



Diseases related to breast sarcoma

Clinical Features for Breast Sarcoma

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Drugs & Therapeutics for Breast Sarcoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Breast Sarcoma

Drug clinical trials:

Search ClinicalTrials for Breast Sarcoma

Search NIH Clinical Center for Breast Sarcoma

Search CenterWatch for Breast Sarcoma

Genetic Tests for Breast Sarcoma

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Anatomical Context for Breast Sarcoma

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32MalaCards
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MalaCards organs/tissues related to Breast Sarcoma:

32
Breast, Myeloid, Bone, Brain, Lung, Lymph node, T cells, B cells, Colon, Cervix

Animal Models for Breast Sarcoma or affiliated genes

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Publications for Breast Sarcoma

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50PubMed
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Articles related to Breast Sarcoma:

(show top 50)    (show all 99)
idTitleAuthorsYear
1
Huge primary soft tissue sarcoma of the breast on bone scan. (24152643)
2014
2
Bilateral ewing sarcoma/primitive neuroectodermal tumor of the breast: a very rare entity and review of the literature. (23819085)
2013
3
Cytologic diagnosis of undifferentiated high grade pleomorphic sarcoma of breast presenting with brain metastasis. (23914101)
2013
4
An unusual breast mass: primary synovial sarcoma. (23784772)
2013
5
Low-grade endometrial stromal sarcoma developing in a postmenopausal woman under toremifene treatment for breast cancer. (22690656)
2013
6
Alveolar soft part sarcoma with breast metastases: a case report. (23263847)
2013
7
Breast sarcoma. (23552541)
2013
8
Breast sarcoma after breast-conserving therapy for breast cancer in a patient with Li-Fraumeni syndrome presenting as focal nonmasslike enhancement on MRI. (24261401)
2013
9
Imaging features of primary breast sarcoma. (22451578)
2012
10
Primary breast sarcoma: prevalence, clinical signs, and radiological features. (21565891)
2011
11
Primary pulmonary synovial sarcoma presenting as a breast mass. (21645168)
2011
12
Two new CHEK2 germ-line variants detected in breast cancer/sarcoma families negative for BRCA1, BRCA2, and TP53 gene mutations. (21562711)
2011
13
Simultaneous Breast Cancer and Kaposi's Sarcoma Complicating Rheumatoid Arthritis. (22291641)
2011
14
Secondary Leukemia in a non-Hodgkin's Lymphoma Patient Presenting as Myeloid Sarcoma of the Breast. (22937314)
2011
15
Treatment for breast sarcoma: a large, single-centre series. (21628089)
2011
16
Myeloid sarcoma involving the breast. (20698144)
2010
17
Immunohistochemistry and molecular analyses in myeloid sarcoma of the breast in a patient with relapse of NPM1-mutated and FLT3-mutated AML after allogeneic stem cell transplantation. (20360144)
2010
18
Alveolar soft part sarcoma presenting as a breast mass in a 13-year-old female. (19021216)
2009
19
Breast sarcoma--a review of diagnosis and management. (19114317)
2009
20
Myeloid sarcoma of the breast mimicking hamartoma on sonography. (19023005)
2008
21
Metastases to the breast: alveolar soft part sarcoma in adolescents. (18501064)
2008
22
Rapid development of post-radiotherapy sarcoma and breast cancer in a patient with a novel germline 'de-novo' TP53 mutation. (17572079)
2007
23
Granulocytic sarcoma of breast: an aleukemic presentation. (17337816)
2007
24
Germline mutations of TP53 and BRCA2 genes in breast cancer/sarcoma families. (17224268)
2007
25
Outcome and prognostic factors in breast sarcoma: a multicenter study from the rare cancer network. (18023492)
2007
26
Report on a case of breast sarcoma metastatic to the axillary lymph nodes. (16724703)
2006
27
Metastatic alveolar soft part sarcoma of the breast. (16798907)
2006
28
Acquired immunodeficiency syndrome-related Kaposi's sarcoma of the axilla and breast after percutaneous intravenous catheter insertion. (15985038)
2005
29
Myeloid sarcoma involving the breast. (15628906)
2005
30
Primary breast sarcoma: case report. (15490711)
2004
31
Delivery of an anticancer drug and a chemosensitizer to murine breast sarcoma by intratumoral injection of sulfopropyl dextran microspheres. (12956895)
2003
32
Breast metastasis from low-grade endometrial stromal sarcoma after a 17-year period. (12439586)
2002
33
An unusual case of metastatic post-irradiation breast sarcoma. (14965694)
2002
34
Radiation-induced breast sarcoma. (12383902)
2002
35
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity. (11687967)
2001
36
Low-grade endometrial stromal sarcoma of the ectocervix after therapy for breast cancer. (11006043)
2000
37
Breast sarcoma. (8610270)
1996
38
Human breast sarcoma and human breast implantation: a time trend analysis based on SEER data (1973-1990). (7722610)
1995
39
Breast sarcoma. A clinicopathologic review of 25 cases. (2386920)
1990
40
High-dose interferon-beta in treatment of spindle-cell sarcoma of breast. (2145946)
1990
41
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. (1978757)
1990
42
Breast sarcoma. (3674288)
1987
43
Breast sarcoma with giant cells and osteoid. A case report and review of the literature. (3826481)
1987
44
Sarcoma following irradiation for breast cancer. Report of three unusual cases including one malignant mesenchymoma of bone. (3030050)
1986
45
Effect of metyrapone and aminoglutethimide on the murine sarcoma (MuSV-M) and breast adenocarcinoma (C3HBA). (228124)
1979
46
Letter: Familial breast cancer, soft-tissue sarcomas, and other neoplasms. (1200533)
1975
47
A breast sarcoma containing rhabdomyosarcomatous and other metaplastic elements. (4099010)
1970
48
Results of 22 cases of breast sarcoma over five years after surgery. (4316262)
1970
49
Recurrent intussusception in an adult, due to intestinal metastases of a breast sarcoma. (13811295)
1959
50
Studies on Hypoproteinemia: III. Lymphoid Hyperplasia and Redistribution of Nitrogen Caused in Mice by Transplanted Tumors (Sarcoma 180 and Breast Adenocarcinoma EO 771). (17735505)
1948

Genetic Variations for Breast Sarcoma

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Expression for genes affiliated with Breast Sarcoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Breast Sarcoma

Search GEO for disease gene expression data for Breast Sarcoma.

Pathways for genes affiliated with Breast Sarcoma

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Sources:
51QIAGEN, 29KEGG, 59Tocris Bioscience
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Compounds for genes affiliated with Breast Sarcoma

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank
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Compounds related to Breast Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1hydroxyurea44 49 1111.2ITGA4, TP53
2vincristine44 49 1111.1ITGA4, TP53
3cycloheximide449.1ITGA4, TP53
4cyclophosphamide44 49 1111.0TP53, ITGA4
5butyrate448.8ITGA4, TP53

GO Terms for genes affiliated with Breast Sarcoma

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16Gene Ontology
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Biological processes related to Breast Sarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:0075969.1TP53, ITGA4

Products for genes affiliated with Breast Sarcoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Breast Sarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet