MCID: BRS061
MIFTS: 30

Breast Sarcoma malady

Cancer diseases category

Summaries for Breast Sarcoma

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32MalaCards
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MalaCards: Breast Sarcoma, also known as sarcoma of breast, is related to sarcoma and breast cancer. An important gene associated with Breast Sarcoma is TP53 (tumor protein p53), and among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. The compounds hydroxyurea and vincristine have been mentioned in the context of this disorder. Affiliated tissues include breast, myeloid and bone.

Aliases & Classifications for Breast Sarcoma

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

breast sarcoma 8
sarcoma of breast 8 60


External Ids:

Disease Ontology8 DOID:3017
SNOMED-CT56 278050001
NCIt39 C4670

Related Diseases for Breast Sarcoma

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Breast Sarcoma:



Diseases related to breast sarcoma

Clinical Features for Breast Sarcoma

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Drugs & Therapeutics for Breast Sarcoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Breast Sarcoma

Drug clinical trials:

Search ClinicalTrials for Breast Sarcoma

Search NIH Clinical Center for Breast Sarcoma

Search CenterWatch for Breast Sarcoma

Genetic Tests for Breast Sarcoma

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Anatomical Context for Breast Sarcoma

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Sources:
32MalaCards
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MalaCards organs/tissues related to Breast Sarcoma:

32
Breast, Myeloid, Bone, Brain, Colon, Lung, Cervix, Lymph node, T cells, B cells

Animal Models for Breast Sarcoma or affiliated genes

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Publications for Breast Sarcoma

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50PubMed
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Articles related to Breast Sarcoma:

(show top 50)    (show all 99)
idTitleAuthorsYear
1
Granulocytic sarcoma of the breast in acute myeloid leukemia: Two case reports. (24348837)
2014
2
Uterine sarcoma after tamoxifen therapy for breast cancer. (24282897)
2013
3
Tamoxifen in breast cancer ipse dixit in uterine malignant mixed MA1llerian tumor and sarcoma-A report of 8 cases and review of the literature. (24416561)
2013
4
Alveolar soft part sarcoma with breast metastases: a case report. (23263847)
2013
5
Breast sarcoma after breast-conserving therapy for breast cancer in a patient with Li-Fraumeni syndrome presenting as focal nonmasslike enhancement on MRI. (24261401)
2013
6
Alveolar Soft Part Sarcoma-A Histological Surprise in a Male Patient who was Suspected to have Breast Cancer. (23730668)
2013
7
Breast sarcoma in a pregnant patient A case report. (23070281)
2012
8
Primary osteogenic sarcoma of the breast: a case report. (23997518)
2012
9
Bilateral myeloid sarcoma of the breast and cerebrospinal fluid as a relapse of acute myeloid leukemia after stem-cell transplantation: a case report. (22734027)
2012
10
Primary breast sarcoma: prevalence, clinical signs, and radiological features. (21565891)
2011
11
Simultaneous Breast Cancer and Kaposi's Sarcoma Complicating Rheumatoid Arthritis. (22291641)
2011
12
Pegylated liposomal doxorubicin: a review of its use in metastatic breast cancer, ovarian cancer, multiple myeloma and AIDS-related Kaposi's sarcoma. (22141391)
2011
13
Diagnosis and management of primary breast sarcoma. (20480227)
2010
14
The ruthenium complex cis-(dichloro)tetraammineruthenium(III) chloride presents selective cytotoxicity against murine B cell lymphoma (A-20), murine ascitic sarcoma 180 (S-180), human breast adenocarcinoma (SK-BR-3), and human T cell leukemia (Jurkat) tumor cell lines. (19727575)
2010
15
Pelvic metastasis of breast synovial sarcoma. (19337816)
2009
16
The co-occurrence of breast cancer and soft tissue sarcoma in a single cohort series. (19194122)
2009
17
Myeloid sarcoma of the breast mimicking hamartoma on sonography. (19023005)
2008
18
Treatment and outcomes of patients with primary breast sarcoma. (18723152)
2008
19
Primary Spindle Cell Sarcoma of the Breast. (20824039)
2008
20
Extramedullary myeloid sarcoma of the breast. (18711198)
2008
21
Metastases to the breast: alveolar soft part sarcoma in adolescents. (18501064)
2008
22
Rapid development of post-radiotherapy sarcoma and breast cancer in a patient with a novel germline 'de-novo' TP53 mutation. (17572079)
2007
23
Unusual lesions in the breast - recurrent metastasis in the breast from uterine sarcoma. (17593054)
2007
24
Metastatic breast tumor arising from synovial sarcoma: report of a case. (17342363)
2007
25
Good outcome after neoadjuvant chemotherapy and extended surgical resection for a large radiation-induced high-grade breast sarcoma. (16824232)
2006
26
Report on a case of breast sarcoma metastatic to the axillary lymph nodes. (16724703)
2006
27
Metastatic alveolar soft part sarcoma of the breast. (16798907)
2006
28
Acquired immunodeficiency syndrome-related Kaposi's sarcoma of the axilla and breast after percutaneous intravenous catheter insertion. (15985038)
2005
29
A rare case of breast sarcoma brain metastases. (15925991)
2005
30
Development of uterine sarcoma after tamoxifen treatment for breast cancer: report of four cases. (16343223)
2005
31
High-grade endometrial stromal sarcoma after tamoxifen therapy for breast cancer. (15920338)
2005
32
Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature. (15187996)
2004
33
Primary breast sarcoma: case report. (15490711)
2004
34
High-grade endometrial stromal sarcoma after treatment with tamoxifen in a patient treated for breast cancer. (14675357)
2003
35
Isolated granulocytic sarcoma in the breast]. (14577316)
2003
36
Low rate of TP53 germline mutations in breast cancer/sarcoma families not fulfilling classical criteria for Li-Fraumeni syndrome. (12471212)
2002
37
P53 expression is a factor for prognostic assessment in breast sarcoma. (12002339)
2002
38
Stromal sarcoma of the breast with leiomyosarcomatous pattern. (12366813)
2002
39
Surgical management of primary breast sarcoma. (12206600)
2002
40
F-18 FDG whole-body positron emission tomography scan in primary breast sarcoma. (9735983)
1998
41
Breast mass due to alveolar soft part sarcoma of the pectoris major muscle. (9056151)
1997
42
Breast sarcoma. (8610270)
1996
43
Alveolar soft part sarcoma metastatic to the breast. (8606550)
1996
44
Radioresponsiveness of human glioma, sarcoma, and breast cancer spheroids depends on tumor differentiation. (8226158)
1993
45
No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung. (1381957)
1992
46
Primary breast sarcoma: a review of 33 cases with immunohistochemistry and prognostic factors. (2468372)
1989
47
Spindle-cell sarcoma of the female breast. (16312854)
1989
48
Breast sarcoma with giant cells and osteoid. (3166604)
1988
49
Sarcoma following irradiation for breast cancer. Report of three unusual cases including one malignant mesenchymoma of bone. (3030050)
1986
50
Results of 22 cases of breast sarcoma over five years after surgery. (4316262)
1970

Genetic Variations for Breast Sarcoma

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Expression for genes affiliated with Breast Sarcoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Breast Sarcoma

Search GEO for disease gene expression data for Breast Sarcoma.

Pathways for genes affiliated with Breast Sarcoma

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Sources:
51QIAGEN, 29KEGG, 59Tocris Bioscience
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Compounds for genes affiliated with Breast Sarcoma

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank
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Compounds related to Breast Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1hydroxyurea44 49 1111.2TP53, ITGA4
2vincristine44 49 1111.1TP53, ITGA4
3cycloheximide449.1TP53, ITGA4
4cyclophosphamide44 49 1111.0ITGA4, TP53
5butyrate448.8TP53, ITGA4

GO Terms for genes affiliated with Breast Sarcoma

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16Gene Ontology
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Biological processes related to Breast Sarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:0075969.1TP53, ITGA4

Products for genes affiliated with Breast Sarcoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Breast Sarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet