MCID: BRS061
MIFTS: 23

Breast Sarcoma malady

Summaries for Breast Sarcoma

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33MalaCards
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MalaCards: Breast Sarcoma, also known as sarcoma of breast, is related to fibrous histiocytoma and breast osteosarcoma. An important gene associated with Breast Sarcoma is TP53 (tumor protein p53), and among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. The compounds hydroxyurea and vincristine have been mentioned in the context of this disorder.

Aliases & Classifications for Breast Sarcoma

Sources:
8Disease Ontology, 61UMLS, 57SNOMED-CT, 40NCIt
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Aliases & Descriptions:

breast sarcoma 8
sarcoma of breast 8 61


External Ids:

Disease Ontology8 DOID:3017
SNOMED-CT57 278050001
NCIt40 C4670

Related Diseases for Breast Sarcoma

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Breast Sarcoma:



Diseases related to breast sarcoma

Clinical Features for Breast Sarcoma

Drugs & Therapeutics for Breast Sarcoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Breast Sarcoma

Drug clinical trials:

Search ClinicalTrials for Breast Sarcoma

Search NIH Clinical Center for Breast Sarcoma

Search CenterWatch for Breast Sarcoma

Genetic Tests for Breast Sarcoma

Anatomical Context for Breast Sarcoma

Animal Models for Breast Sarcoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Breast Sarcoma

Sources:
51PubMed
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Articles related to Breast Sarcoma:

(show top 50)    (show all 108)
idTitleAuthorsYear
1
Granulocytic sarcoma of the breast in acute myeloid leukemia: Two case reports. (24348837)
2014
2
Tamoxifen in breast cancer ipse dixit in uterine malignant mixed MA1llerian tumor and sarcoma-A report of 8 cases and review of the literature. (24416561)
2013
3
Alveolar soft part sarcoma with breast metastases: a case report. (23263847)
2013
4
Breast sarcoma. (23552541)
2013
5
Breast sarcoma after breast-conserving therapy for breast cancer in a patient with Li-Fraumeni syndrome presenting as focal nonmasslike enhancement on MRI. (24261401)
2013
6
Alveolar Soft Part Sarcoma-A Histological Surprise in a Male Patient who was Suspected to have Breast Cancer. (23730668)
2013
7
Breast sarcoma in a pregnant patient A case report. (23070281)
2012
8
Bilateral myeloid sarcoma of the breast and cerebrospinal fluid as a relapse of acute myeloid leukemia after stem-cell transplantation: a case report. (22734027)
2012
9
A progesterone-receptor-positive huge retroperitoneal tumour mimics metastasis in a breast cancer patient: sarcomatoid renal cell carcinoma. (21618856)
2011
10
Pegylated liposomal doxorubicin: a review of its use in metastatic breast cancer, ovarian cancer, multiple myeloma and AIDS-related Kaposi's sarcoma. (22141391)
2011
11
The ruthenium complex cis-(dichloro)tetraammineruthenium(III) chloride presents selective cytotoxicity against murine B cell lymphoma (A-20), murine ascitic sarcoma 180 (S-180), human breast adenocarcinoma (SK-BR-3), and human T cell leukemia (Jurkat) tumor cell lines. (19727575)
2010
12
Primary breast synovial sarcoma: a rare primary breast neoplasm. (20045794)
2009
13
Phase I clinical and pharmacokinetic study of trabectedin and doxorubicin in advanced soft tissue sarcoma and breast cancer. (19114300)
2009
14
Alveolar soft part sarcoma presenting as a breast mass in a 13-year-old female. (19021216)
2009
15
Pelvic metastasis of breast synovial sarcoma. (19337816)
2009
16
Primary breast sarcoma. (18514698)
2008
17
Treatment and outcomes of patients with primary breast sarcoma. (18723152)
2008
18
Primary Spindle Cell Sarcoma of the Breast. (20824039)
2008
19
Extramedullary myeloid sarcoma of the breast. (18711198)
2008
20
Metastases to the breast: alveolar soft part sarcoma in adolescents. (18501064)
2008
21
Sarcomatoid renal cell carcinoma metastatic to the breast: report of a case with diagnosis on fine needle aspiration cytology. (17536553)
2007
22
Unusual lesions in the breast - recurrent metastasis in the breast from uterine sarcoma. (17593054)
2007
23
Spindle cell (sarcomatoid) carcinoma of the breast: a clinicopathologic and immunohistochemical analysis of 29 cases. (16538049)
2006
24
Metastatic alveolar soft part sarcoma of the breast. (16798907)
2006
25
A rare case of breast sarcoma brain metastases. (15925991)
2005
26
Development of uterine sarcoma after tamoxifen treatment for breast cancer: report of four cases. (16343223)
2005
27
Metaplastic breast carcinomas: are they of myoepithelial differentiation?: immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers. (15725803)
2005
28
High-grade endometrial stromal sarcoma after tamoxifen therapy for breast cancer. (15920338)
2005
29
Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature. (15187996)
2004
30
Primary breast sarcoma: case report. (15490711)
2004
31
High-grade endometrial stromal sarcoma after treatment with tamoxifen in a patient treated for breast cancer. (14675357)
2003
32
Breast sarcoma showing myofibroblastic differentiation. (12844261)
2003
33
P53 expression is a factor for prognostic assessment in breast sarcoma. (12002339)
2002
34
Stromal sarcoma of the breast with leiomyosarcomatous pattern. (12366813)
2002
35
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity. (11687967)
2001
36
Verapamil decreases accumulation of 99Tcm-MIBI and 99Tcm-tetrofosmin in human breast cancer and soft tissue sarcoma cell lines. (11403175)
2001
37
Low-grade endometrial stromal sarcoma of the ectocervix after therapy for breast cancer. (11006043)
2000
38
Sarcomatoid carcinoma in breast]. (11866908)
2000
39
Myxoid variant of follicular dendritic cell sarcoma arising in the breast. (10196389)
1999
40
F-18 FDG whole-body positron emission tomography scan in primary breast sarcoma. (9735983)
1998
41
Breast mass due to alveolar soft part sarcoma of the pectoris major muscle. (9056151)
1997
42
Intense uptake of technetium-99m-MDP in primary breast adenocarcinoma with sarcomatoid metaplasia. (9098196)
1997
43
Alveolar soft part sarcoma metastatic to the breast. (8606550)
1996
44
Radioresponsiveness of human glioma, sarcoma, and breast cancer spheroids depends on tumor differentiation. (8226158)
1993
45
Breast sarcoma. A clinicopathologic review of 25 cases. (2386920)
1990
46
High-dose interferon-beta in treatment of spindle-cell sarcoma of breast. (2145946)
1990
47
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. (1978757)
1990
48
Breast sarcoma. (3674288)
1987
49
Sarcoma following irradiation for breast cancer. Report of three unusual cases including one malignant mesenchymoma of bone. (3030050)
1986
50
A breast sarcoma containing rhabdomyosarcomatous and other metaplastic elements. (4099010)
1970

Genetic Variations for Breast Sarcoma

Expression for genes affiliated with Breast Sarcoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Breast Sarcoma

Search GEO for disease gene expression data for Breast Sarcoma.

Pathways for genes affiliated with Breast Sarcoma

Sources:
52QIAGEN, 30KEGG, 60Tocris Bioscience
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Compounds for genes affiliated with Breast Sarcoma

Sources:
45Novoseek, 50PharmGKB, 11DrugBank
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Compounds related to Breast Sarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1hydroxyurea45 50 1111.2TP53, ITGA4
2vincristine45 50 1111.1TP53, ITGA4
3cycloheximide459.1TP53, ITGA4
4cyclophosphamide45 50 1111.0ITGA4, TP53
5butyrate458.8TP53, ITGA4

GO Terms for genes affiliated with Breast Sarcoma

Sources:
16Gene Ontology
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Biological processes related to Breast Sarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:0075969.1TP53, ITGA4

Products for genes affiliated with Breast Sarcoma

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Sources for Breast Sarcoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet