MCID: BRS042
MIFTS: 33

Breast Scirrhous Carcinoma malady

Category: Cancer diseases

Aliases & Classifications for Breast Scirrhous Carcinoma

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Aliases & Descriptions for Breast Scirrhous Carcinoma:

Name: Breast Scirrhous Carcinoma 10 12
Infiltrating Carcinoma of Breast with Fibrotic Stroma 10
 
Scirrhous Carcinoma of Breast 10

Classifications:



External Ids:

Disease Ontology10 DOID:7578
SNOMED-CT59 254839007
NCIt42 C7362
UMLS65 C0346151

Summaries for Breast Scirrhous Carcinoma

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MalaCards based summary: Breast Scirrhous Carcinoma, also known as infiltrating carcinoma of breast with fibrotic stroma, is related to flat ductal epithelial atypia and pagod syndrome. An important gene associated with Breast Scirrhous Carcinoma is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways are Alzheimers Disease Pathway and Agrin Interactions at Neuromuscular Junction. Affiliated tissues include breast, prostate and thymus, and related mouse phenotypes are embryo and tumorigenesis.

Related Diseases for Breast Scirrhous Carcinoma

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Diseases related to Breast Scirrhous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 146)
idRelated DiseaseScoreTop Affiliating Genes
1flat ductal epithelial atypia10.4EGFR, ERBB2
2pagod syndrome10.4ERBB2, MUC1
3eccrine papillary adenocarcinoma10.4EGFR, ERBB2
4protein-deficiency anemia10.4EGFR, ERBB2
5nasal cavity squamous cell carcinoma10.4EGFR, ERBB2
6toxic encephalopathy10.3EGFR, ERBB2
7thymus adenocarcinoma10.3ERBB2, MUC1
8mediastinal neurilemmoma10.3EGFR, ERBB2
9cavernous hemangioma10.3EGFR, ERBB2
10ampullary signet ring cell adenocarcinoma10.3EGFR, ERBB2
11sclerosing hemangioma10.3EGFR, ERBB2
12bacterial exanthem10.3EGFR, ERBB2
13bile duct mucoepidermoid carcinoma10.3ERBB2, PGR
14ovarian mesodermal adenosarcoma10.3ERBB2, PGR
15acute retinal necrosis syndrome10.2ERBB2, PGR
16lupus erythematosus10.2EGFR, ERBB2
17paroxysmal choreoathetosis10.2EGFR, ERBB2
18renal tubular acidosis, distal, autosomal recessive10.2EGFR, MUC1
19intramuscular hemangioma10.2MUC1, PGR
20familial short qt syndrome10.2EGFR, MUC1
21synchronous bilateral breast carcinoma10.2ERBB2, PGR
22malignant teratocarcinosarcoma10.2MUC1, PGR
23gorham's disease10.2EGFR, MUC1
24fallopian tube leiomyosarcoma10.2ERBB2, PGR
25pancreatic ductal adenocarcinoma10.2EGFR, MUC1
26dyskinetic cerebral palsy10.2ERBB2, PGR
27postpoliomyelitis syndrome10.2MUC1, PGR
28cervical endometrial stromal sarcoma10.1ERBB2, MUC1
29oral tuberculosis10.1MUC1, PGR
30pituitary gland disease10.1ERBB2, ESR1
31pyometritis10.1EGFR, MUC1
32cribriform carcinoma10.1ERBB2, ESR1
33serous cystadenocarcinoma10.1ERBB2, MUC1
34diverticulitis10.0EGFR, MUC1
35progesterone-receptor positive breast cancer10.0ERBB2, ESR1
36tenosynovitis of foot and ankle10.0EGFR, ERBB2
37vulvar angiokeratoma10.0ESR1, MUC1
38tubular adenocarcinoma10.0EGFR, MUC1
39fallopian tube carcinosarcoma10.0MUC1, PGR
40syringoma9.9ESR1, PGR
41endocrine organ benign neoplasm9.9ESR1, PGR
42cervical benign neoplasm9.9ESR1, PGR
43large bowel leiomyoma9.9ESR1, PGR
44bile duct cystadenoma9.9ESR1, PGR
45venous tributary occlusion of retina9.9ESR1, PGR
46deafness, autosomal dominant 8/129.9ESR1, PGR
47peroneal nerve paralysis9.9ESR1, PGR
48vulvar squamous papilloma9.9ESR1, PGR
49extragonadal nonseminomatous germ cell tumor9.9ESR1, PGR
50vulvar alveolar soft part sarcoma9.9ESR1, PGR

Graphical network of the top 20 diseases related to Breast Scirrhous Carcinoma:



Diseases related to breast scirrhous carcinoma

Symptoms for Breast Scirrhous Carcinoma

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Drugs & Therapeutics for Breast Scirrhous Carcinoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Breast Scirrhous Carcinoma

Genetic Tests for Breast Scirrhous Carcinoma

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Anatomical Context for Breast Scirrhous Carcinoma

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MalaCards organs/tissues related to Breast Scirrhous Carcinoma:

33
Breast, Prostate, Thymus, Ovary, Pituitary, Endothelial, Uterus

Animal Models for Breast Scirrhous Carcinoma or affiliated genes

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MGI Mouse Phenotypes related to Breast Scirrhous Carcinoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.5EGFR, ERBB2, ESR1, PGR
2MP:00020068.5EGFR, ERBB2, ESR1, PGR
3MP:00107718.4EGFR, ERBB2, ESR1, PGR
4MP:00053718.4EGFR, ERBB2, ESR1, PGR
5MP:00053698.3EGFR, ERBB2, ESR1, PGR

Publications for Breast Scirrhous Carcinoma

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Articles related to Breast Scirrhous Carcinoma:

idTitleAuthorsYear
1
Establishment and characterization of HER2-positive cell line derived from pleural effusion of human breast scirrhous carcinoma. (19067762)
2008
2
Establishment and characterization of a cell line (NABCA) derived from metastatic lymph nodes of breast scirrhous carcinoma. (17257375)
2006

Variations for Breast Scirrhous Carcinoma

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Expression for genes affiliated with Breast Scirrhous Carcinoma

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Search GEO for disease gene expression data for Breast Scirrhous Carcinoma.

Pathways for genes affiliated with Breast Scirrhous Carcinoma

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GO Terms for genes affiliated with Breast Scirrhous Carcinoma

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Cellular components related to Breast Scirrhous Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1basolateral plasma membraneGO:00163239.5EGFR, ERBB2

Biological processes related to Breast Scirrhous Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol-mediated signalingGO:00480159.8EGFR, ERBB2
2peptidyl-tyrosine phosphorylationGO:00181089.6EGFR, ERBB2
3transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.5EGFR, ERBB2
4positive regulation of cell growthGO:00303079.5EGFR, ERBB2
5ERBB2 signaling pathwayGO:00381289.4EGFR, ERBB2

Molecular functions related to Breast Scirrhous Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor signaling protein tyrosine kinase activityGO:00047169.5EGFR, ERBB2

Sources for Breast Scirrhous Carcinoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet