MCID: BRS042
MIFTS: 29

Breast Scirrhous Carcinoma malady

Category: Cancer diseases

Aliases & Classifications for Breast Scirrhous Carcinoma

About this section

Aliases & Descriptions for Breast Scirrhous Carcinoma:

Name: Breast Scirrhous Carcinoma 10 12
Infiltrating Carcinoma of Breast with Fibrotic Stroma 10
 
Scirrhous Carcinoma of Breast 10

Classifications:



External Ids:

Disease Ontology10 DOID:7578
SNOMED-CT59 254839007
NCIt42 C7362
UMLS65 C0346151

Summaries for Breast Scirrhous Carcinoma

About this section
MalaCards based summary: Breast Scirrhous Carcinoma, also known as infiltrating carcinoma of breast with fibrotic stroma, is related to flat ductal epithelial atypia and pagod syndrome. An important gene associated with Breast Scirrhous Carcinoma is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways are Alzheimers Disease Pathway and Agrin Interactions at Neuromuscular Junction. Affiliated tissues include breast, and related mouse phenotypes are embryo and tumorigenesis.

Related Diseases for Breast Scirrhous Carcinoma

About this section

Diseases related to Breast Scirrhous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 148)
idRelated DiseaseScoreTop Affiliating Genes
1flat ductal epithelial atypia10.3EGFR, ERBB2
2pagod syndrome10.2ERBB2, MUC1
3eccrine papillary adenocarcinoma10.2EGFR, ERBB2
4protein-deficiency anemia10.2EGFR, ERBB2
5nasal cavity squamous cell carcinoma10.2EGFR, ERBB2
6toxic encephalopathy10.2EGFR, ERBB2
7thymus adenocarcinoma10.2ERBB2, MUC1
8mediastinal neurilemmoma10.2EGFR, ERBB2
9cavernous hemangioma10.2EGFR, ERBB2
10ampullary signet ring cell adenocarcinoma10.2EGFR, ERBB2
11sclerosing hemangioma10.2EGFR, ERBB2
12bacterial exanthem10.2EGFR, ERBB2
13bile duct mucoepidermoid carcinoma10.2ERBB2, PGR
14ovarian mesodermal adenosarcoma10.2ERBB2, PGR
15acute retinal necrosis syndrome10.2ERBB2, PGR
16lupus erythematosus10.2EGFR, ERBB2
17paroxysmal choreoathetosis10.1EGFR, ERBB2
18renal tubular acidosis, distal, autosomal recessive10.1EGFR, MUC1
19intramuscular hemangioma10.1MUC1, PGR
20familial short qt syndrome10.1EGFR, MUC1
21synchronous bilateral breast carcinoma10.1ERBB2, PGR
22malignant teratocarcinosarcoma10.1MUC1, PGR
23gorham's disease10.1EGFR, MUC1
24leukemia10.1
25endotheliitis10.1
26fallopian tube leiomyosarcoma10.1ERBB2, PGR
27pancreatic ductal adenocarcinoma10.1EGFR, MUC1
28dyskinetic cerebral palsy10.1ERBB2, PGR
29postpoliomyelitis syndrome10.1MUC1, PGR
30cervical endometrial stromal sarcoma10.1ERBB2, MUC1
31oral tuberculosis10.1MUC1, PGR
32pituitary gland disease10.1ERBB2, ESR1
33pyometritis10.1EGFR, MUC1
34cribriform carcinoma10.1ERBB2, ESR1
35serous cystadenocarcinoma10.0ERBB2, MUC1
36diverticulitis10.0EGFR, MUC1
37progesterone-receptor positive breast cancer10.0ERBB2, ESR1
38tenosynovitis of foot and ankle10.0EGFR, ERBB2
39vulvar angiokeratoma10.0ESR1, MUC1
40tubular adenocarcinoma10.0EGFR, MUC1
41fallopian tube carcinosarcoma10.0MUC1, PGR
42syringoma10.0ESR1, PGR
43endocrine organ benign neoplasm10.0ESR1, PGR
44cervical benign neoplasm10.0ESR1, PGR
45large bowel leiomyoma10.0ESR1, PGR
46bile duct cystadenoma10.0ESR1, PGR
47venous tributary occlusion of retina10.0ESR1, PGR
48deafness, autosomal dominant 8/1210.0ESR1, PGR
49peroneal nerve paralysis10.0ESR1, PGR
50vulvar squamous papilloma10.0ESR1, PGR

Graphical network of the top 20 diseases related to Breast Scirrhous Carcinoma:



Diseases related to breast scirrhous carcinoma

Symptoms for Breast Scirrhous Carcinoma

About this section

Drugs & Therapeutics for Breast Scirrhous Carcinoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Breast Scirrhous Carcinoma

Genetic Tests for Breast Scirrhous Carcinoma

About this section

Anatomical Context for Breast Scirrhous Carcinoma

About this section

MalaCards organs/tissues related to Breast Scirrhous Carcinoma:

33
Breast

Animal Models for Breast Scirrhous Carcinoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Breast Scirrhous Carcinoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.5EGFR, ERBB2, ESR1, PGR
2MP:00020068.5EGFR, ERBB2, ESR1, PGR
3MP:00107718.4EGFR, ERBB2, ESR1, PGR
4MP:00053718.4EGFR, ERBB2, ESR1, PGR
5MP:00053698.3EGFR, ERBB2, ESR1, PGR

Publications for Breast Scirrhous Carcinoma

About this section

Articles related to Breast Scirrhous Carcinoma:

idTitleAuthorsYear
1
Retracted: Pulmonary hypertension due to a pulmonary artery leiomyosarcoma: A case report. (26478736)
2015
2
HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. (22036626)
2012

Variations for Breast Scirrhous Carcinoma

About this section

Expression for genes affiliated with Breast Scirrhous Carcinoma

About this section
Search GEO for disease gene expression data for Breast Scirrhous Carcinoma.

Pathways for genes affiliated with Breast Scirrhous Carcinoma

About this section

GO Terms for genes affiliated with Breast Scirrhous Carcinoma

About this section

Cellular components related to Breast Scirrhous Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1basolateral plasma membraneGO:00163239.5EGFR, ERBB2

Biological processes related to Breast Scirrhous Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol-mediated signalingGO:00480159.8EGFR, ERBB2
2peptidyl-tyrosine phosphorylationGO:00181089.6EGFR, ERBB2
3transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.5EGFR, ERBB2
4positive regulation of cell growthGO:00303079.5EGFR, ERBB2
5ERBB2 signaling pathwayGO:00381289.4EGFR, ERBB2

Molecular functions related to Breast Scirrhous Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor signaling protein tyrosine kinase activityGO:00047169.5EGFR, ERBB2

Sources for Breast Scirrhous Carcinoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet