Aliases & Classifications for Bronchiolitis

Aliases & Descriptions for Bronchiolitis:

Name: Bronchiolitis 12 52 3 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2942
MeSH 42 D001988
NCIt 47 C39658
SNOMED-CT 64 4120002
UMLS 69 C0006271

Summaries for Bronchiolitis

CDC : 3 Respiratory syncytial (sin-SISH-uhl) virus, or RSV, is a common respiratory virus that usually causes mild, cold-like symptoms. Most people recover in a week or two, but RSV can be serious, especially for infants and older adults. In fact, RSV is the most common cause of bronchiolitis (inflammation of the small airways in the lung) and pneumonia (infection of the lungs) in children younger than 1 year of age in the United States. It is also a significant cause of respiratory illness in older adults.

MalaCards based summary : Bronchiolitis is related to nasopharyngitis and hepatitis, and has symptoms including cough, wheezing and shortness of breath. An important gene associated with Bronchiolitis is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Bromhexine and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and bone, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria. The disease has symptom cough, has symptom wheezing, has symptom shortness of breath, has symptom fever, has symptom nasal flaring in infants and has symptom bluish skin due to lack of oxygen.

Wikipedia : 71 Bronchiolitis is inflammation of the bronchioles, the smallest air passages of the lungs. It usually... more...

Related Diseases for Bronchiolitis

Diseases related to Bronchiolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 455)
id Related Disease Score Top Affiliating Genes
1 nasopharyngitis 29.9 CXCL8 IFNG IL4 IL6 TLR10 TNF
2 hepatitis 29.9 IFNG IL10 IL6 TNF
3 primary ciliary dyskinesia 29.6 IL10 IL6 TNF
4 tuberculosis 29.5 CD40LG IL10 IL4 IL6 TNF
5 histiocytosis 29.4 CXCL8 IL6 TLR4 TNF
6 cryptococcosis 29.3 CD40LG IL10 TNF
7 lymphoblastic leukemia 29.2 CCL11 IL13 IL4 IL5
8 hyperlucent lung 29.2 CD40LG IFNG TLR4 TLR6
9 pulmonary eosinophilia 29.1 CD40LG CXCL8 IFNG IL10 IL6 TNF
10 rheumatoid arthritis 29.0 CCL3 CCL5 CD40LG CXCL8 IFNG IL10
11 nonspecific interstitial pneumonia 29.0 CD40LG IFNG IL10 IL4 IL6 TNF
12 pulmonary tuberculosis 26.0 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG
13 bronchiolitis obliterans 12.5
14 respiratory bronchiolitis-interstitial lung disease syndrome 12.0
15 cryptogenic organizing pneumonia 11.9
16 bronchiolitis obliterans with obstructive pulmonary disease 11.9
17 panbronchiolitis, diffuse 11.1
18 bronchitis 11.1
19 bronchopneumonia 11.0
20 parainfluenza virus type 3 11.0
21 swyer-james syndrome 11.0
22 bronchiectasis 11.0
23 interstitial pneumonitis, desquamative, familial 10.9
24 bronchial disease 10.9
25 extrinsic allergic alveolitis 10.7
26 in situ pulmonary adenocarcinoma 10.7
27 surfactant metabolism dysfunction, pulmonary, 5 10.7
28 pneumonia 10.7
29 pyridoxal 5'-phosphate-dependent epilepsy 10.3 IL10 TNF
30 neonatal hypoxic and ischemic brain injury 10.3 CXCL8 IL10 IL6
31 thymic neuroendocrine carcinoma 10.3 CXCL8 IL6 TNF
32 severe combined immunodeficiency, t cell-negative, b-cell/natural killer-cell positive 10.3 IFNG IL10 TNF
33 childhood electroclinical syndrome 10.3 CXCL8 IL10 IL6
34 amyotrophic lateral sclerosis type 14 10.3 CXCL8 IFNG TNF
35 myoglobinuria recurrent 10.3 IFNG IL4
36 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.3 CCL5 IL6 TNF
37 glucose intolerance 10.3 CXCL8 IFNG TNF
38 transient tic disorder 10.3 IL10 IL6 TNF
39 coronary arterial fistulas 10.3 CXCL8 IL10 TLR4
40 lepromatous leprosy 10.3 IFNG IL10 IL6
41 asymptomatic neurosyphilis 10.3 IFNG IL10 IL4
42 tubular renal disease-cardiomyopathy syndrome 10.3 IL10 IL4 TNF
43 immunodeficiency due to a late component of complement deficiency 10.3 CXCL8 IFNG IL10
44 cicatricial lagophthalmos 10.3 CXCL8 IL6 TNF
45 acquired thrombocytopenia 10.3 CXCL8 IL6 TNF
46 autosomal dominant deafness-onychodystrophy syndrome 10.3 IFNG IL4 TNF
47 fallopian tube serous adenocarcinoma 10.3 CXCL8 IL10 IL6
48 lagophthalmos 10.3 IL10 IL4 TNF
49 tungiasis 10.3 IFNG IL10 IL4
50 phlyctenulosis 10.3 IL10 IL6 TNF

Graphical network of the top 20 diseases related to Bronchiolitis:



Diseases related to Bronchiolitis

Symptoms & Phenotypes for Bronchiolitis

Symptoms:

12
  • cough
  • wheezing
  • shortness of breath
  • fever
  • nasal flaring in infants
  • bluish skin due to lack of oxygen

MGI Mouse Phenotypes related to Bronchiolitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.21 TNF CCL11 CCL5 CD40LG IFNG IL10
2 immune system MP:0005387 10.17 CCL11 CCL5 CD40LG IFNG IL10 IL13
3 digestive/alimentary MP:0005381 10.06 IFNG IL10 IL13 IL4 IL4R IL5
4 integument MP:0010771 9.91 TLR4 TNF CD40LG IFNG IL10 IL13
5 liver/biliary system MP:0005370 9.76 IFNG IL10 IL4 IL4R IL5 IL6
6 reproductive system MP:0005389 9.65 TLR6 TNF IL5 IL6 TLR4 CD40LG
7 respiratory system MP:0005388 9.36 CCL11 IFNG IL10 IL13 IL4 IL4R

Drugs & Therapeutics for Bronchiolitis

Drugs for Bronchiolitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 213)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bromhexine Approved Phase 4 3572-43-8
2
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
5
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
6
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
7
Montelukast Approved Phase 4,Phase 3,Phase 2 158966-92-8 5281040
8
Erythromycin Approved, Vet_approved Phase 4 114-07-8 12560
9
Mechlorethamine Approved Phase 4,Phase 3,Phase 2 51-75-2 4033
10
Azithromycin Approved Phase 4,Phase 2,Phase 3,Phase 1 83905-01-5 55185 53477736 447043
11
Aztreonam Approved Phase 4 78110-38-0 5362041 5742832
12
Clarithromycin Approved Phase 4,Phase 3 81103-11-9 84029
13
Azathioprine Approved Phase 4 446-86-6 2265
14
Everolimus Approved Phase 4,Phase 3 159351-69-6 6442177
15
Prednisone Approved, Vet_approved Phase 4,Phase 1,Phase 2 53-03-2 5865
16
Sirolimus Approved, Investigational Phase 4,Phase 3 53123-88-9 5284616 6436030 46835353
17
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 104987-11-3 445643 439492
18
Macitentan Approved Phase 4 441798-33-0
19
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2 67-97-0 6221 10883523 5280795
20
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2 50-14-6 5280793
21 Epinephryl borate Phase 4,Phase 3,Phase 2
22 Racepinephrine Phase 4,Phase 3,Phase 2
23 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1
24 Adrenergic Agonists Phase 4,Phase 3,Phase 2,Phase 1
25 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2
26 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2,Phase 1
27 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
29 Bronchodilator Agents Phase 4,Phase 3,Phase 2,Phase 1
30 Mydriatics Phase 4,Phase 3,Phase 2
31 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
32 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
33 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Vasoconstrictor Agents Phase 4,Phase 3,Phase 2
35 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1
36 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1
38 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1
39 Dexamethasone 21-phosphate Phase 4,Phase 3,Phase 2,Phase 1
40 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1 1177-87-3
41 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
42 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
43 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
44 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
45 Hormones Phase 4,Phase 3,Phase 2,Phase 1
46 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
47
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
48 Bone Density Conservation Agents Phase 4,Phase 3,Phase 2
49 Ergocalciferols Phase 4,Phase 3,Phase 2
50 Micronutrients Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 269)
id Name Status NCT ID Phase
1 Home Oxygen Therapy in Bronchiolitis Unknown status NCT01216553 Phase 4
2 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4
3 Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department Unknown status NCT01660867 Phase 4
4 Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection Unknown status NCT02054182 Phase 4
5 Evaluation and Reconditioning of Marginal Lung Donors to Transplantation by ex Vivo Lung Perfusion Unknown status NCT01353105 Phase 4
6 Nebulized 5% Hypertonic Saline for the Treatment of Bronchiolitis Completed NCT01016249 Phase 4
7 Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety Completed NCT01834820 Phase 4
8 7% Hypertonic Saline for Acute Bronchiolitis Completed NCT01871857 Phase 4
9 Effectiveness of Nebulized Hypertonic Saline and Epinephrine in Hospitalized Infants With Bronchiolitis Completed NCT01300325 Phase 4
10 Glucocorticoid Therapy Impact on the Inflammatory Response and Clinical Evolution in Patients With Severe Bronchiolitis Completed NCT02571517 Phase 4
11 Efficacy of Nebulised Hypertonic Saline (3%) Among Children With Bronchiolitis. Completed NCT01276821 Phase 4
12 Hypertonic Saline for Acute Bronchiolitis Completed NCT01247064 Phase 4
13 Impact of Oximetry on Hospitalization in Acute Bronchiolitis Completed NCT00673946 Phase 4
14 Bronchodilator Responsiveness in Obliterative Bronchiolitis Completed NCT01112241 Phase 4
15 Vitamin D in Bronchiolitis Obliterans Syndrome Completed NCT01212406 Phase 4
16 Montelukast in Bronchiolitis Obliterans Syndrome Completed NCT01211509 Phase 4
17 Nebulized 3% Hypertonic Saline Solution Treatment of Bronchiolitis in Infants Completed NCT02233985 Phase 4
18 Use of Erythromycin in Mustard-Induced Bronchiolitis Completed NCT00367419 Phase 4
19 The Effectiveness of Oral Dexamethasone for Acute Bronchiolitis Completed NCT00119002 Phase 4
20 Azithromycin in Bronchiolitis Obliterans Syndrome Completed NCT01009619 Phase 4
21 Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung Transplantation Completed NCT01109160 Phase 4
22 Safety Study of Aztreonam Lysine for Inhalation (AZLI) in the Treatment of Early Bronchiolitis Obliterans Syndrome (BOS) Completed NCT01469364 Phase 4
23 Chronic Bronchiolitis or Resistant Asthma? Completed NCT00368342 Phase 4
24 Comparison of Sirolimus and Azathioprine in Lung Transplantation Completed NCT00321906 Phase 4
25 High Flow Nasal Cannula vs Low Flow Oxygen Therapy in Bronchiolitis Recruiting NCT03015051 Phase 4
26 Comparison of High Flow Oxygenation Therapy and CPAP in Children With Bronchiolitis. Recruiting NCT02618213 Phase 4
27 Efficacy and Safety of 3% Hypertonic Saline Inhalation (24h vs 72h) to Treat Acute Bronchiolitis in Hospitalized Infants Recruiting NCT02538458 Phase 4
28 Assessment of Thoracic Echography for Pleuroparenchymatous Anomaly Diagnosis Complicating Bronchiolitis: BronchioIUS Not yet recruiting NCT02890797 Phase 4
29 Macitentan in the Treatment of Organ Rejection After Lung Transplantation Not yet recruiting NCT02893176 Phase 4
30 Acoustic Assessment of Nebulized Epinephrine Versus Albuterol for RSV Bronchiolitis- a Double Blind Study Terminated NCT00361452 Phase 4
31 Heliox-Driven Racemic Epinephrine Nebulization in Treatment of Moderate to Severe Bronchiolitis in Pediatric ED Patients Completed NCT00116584 Phase 3
32 An Investigational Drug Study to Treat Respiratory Symptoms Associated With Respiratory Syncytial Virus (RSV) Bronchiolitis (0476-272) Completed NCT00076973 Phase 3
33 Nebulized Hypertonic Saline for Bronchiolitis Completed NCT00619918 Phase 2, Phase 3
34 Single Dose Versus Multiple Doses of Dexamethasone in Children With Acute Bronchiolitis Completed NCT00213226 Phase 3
35 Nasal Irrigation in Infants With Bronchiolitis. Completed NCT02162745 Phase 3
36 Safety Study of Home Oxygen Therapy for Children With Acute Bronchiolitis Completed NCT00677066 Phase 3
37 The SABRE Trial of Hypertonic Saline in Acute Bronchiolitis Completed NCT01469845 Phase 3
38 Efficacy of Zinc in the Treatment of Bronchiolitis and Prevention of Wheezing Respiratory Illness in Children Less Than Two Years Old Completed NCT00355043 Phase 3
39 High Flow Therapy vs Hypertonic Saline in Bronchiolitis Completed NCT01873144 Phase 3
40 Moderate to Severe Bronchiolitis: Standard Therapy Versus Therapy With NaCl 3% Inhalations Completed NCT01812525 Phase 3
41 The Use of an Inhaled Salt Solution to Treat Viral Lung Infections in Infants. Completed NCT00151905 Phase 2, Phase 3
42 Effect of Heliox on RSV Bronchiolitis Completed NCT03171142 Phase 3
43 Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis Completed NCT01777347 Phase 3
44 Tacrolimus Versus Cyclosporine for Immunosuppression After Lung Transplantation Completed NCT01429844 Phase 3
45 Use of Clarithromycin in Mustard-Induced Bronchiolitis Completed NCT00381147 Phase 3
46 Study of Cyclosporine Inhalation Solution (CIS) in Improving Bronchiolitis Obliterans Syndrome-Free Survival Following Lung Transplantation Completed NCT00755781 Phase 3
47 Study Comparing Simulect Plus Standard Immunosuppression to Standard Immunosuppression Alone for the Prevention of Acute Rejection and Bronchiolitis Obliterans in Lung Transplant Completed NCT00188825 Phase 3
48 Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients Completed NCT00512811 Phase 3
49 Effect of Supplementation With Vitamin D on the Acute Bronchitis Prevention During the First Year of Life Completed NCT01875757 Phase 3
50 Helium:Oxygen Noninvasive Positive Pressure Ventilation in Patients Exposed to Sulfur Mustard Completed NCT00642447 Phase 2, Phase 3

Search NIH Clinical Center for Bronchiolitis

Cochrane evidence based reviews: bronchiolitis

Genetic Tests for Bronchiolitis

Anatomical Context for Bronchiolitis

MalaCards organs/tissues related to Bronchiolitis:

39
Lung, Skin, Bone, Breast, Bone Marrow, T Cells, Neutrophil

Publications for Bronchiolitis

Articles related to Bronchiolitis:

(show top 50) (show all 1435)
id Title Authors Year
1
The Calculated Risk of Childhood Asthma From Severe Bronchiolitis. ( 28065346 )
2017
2
Respiratory reactance in children aged three to fiveA years with postinfectious bronchiolitis obliterans is higher than in those with asthma. ( 27743492 )
2017
3
Bronchiolitis obliterans syndrome in adults after allogeneic stem cell transplantation-pathophysiology, diagnostics and treatment. ( 28052713 )
2017
4
An autopsy case of bronchiolitis obliterans as a previously unrecognized adverse event of afatinib treatment. ( 28012496 )
2017
5
Respiratory Syncytial Virus Bronchiolitis in Children. ( 28084708 )
2017
6
Prevention of bronchiolitis obliterans-the realization of a hope? ( 27667135 )
2016
7
Short-Term Variation of Lung Function and Airway Inflammation in Children and Adolescents with Bronchiolitis Obliterans. ( 27325047 )
2016
8
Phenytoin induced Steven-Johnson syndrome and bronchiolitis obliterans - case report and review of literature. ( 27222786 )
2016
9
Effectiveness of 3% hypertonic saline nebulization in acute bronchiolitis among Indian children: A quasi-experimental study. ( 27141475 )
2016
10
Nebulised hypertonic saline inhalations do not shorten hospital stays in infants with bronchiolitis. ( 27111485 )
2016
11
Bronchiolitis obliterans organising pneumonia associated with anticonvulsant hypersensitivity syndrome induced by lamotrigine. ( 26825933 )
2016
12
Pulmonary hemorrhage as a complication of Respiratory Syncyntial Virus (RSV) bronchiolitis. ( 28029754 )
2016
13
Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplantation. ( 27513368 )
2016
14
Early outcomes of lung transplantation for bronchiolitis obliterans syndrome after allogeneic haematopoietic stem cell transplantation: a single-centre experience. ( 27481680 )
2016
15
Viral Bronchiolitis in Children. ( 27144868 )
2016
16
Bronchiolitis: More Evidence, Fewer Interventions. Shifting paradigms with evidence based diagnostics. ( 27664941 )
2016
17
The Impact of Alemtuzumab and Basiliximab Induction on Patient Survival and Time to Bronchiolitis Obliterans Syndrome in Double Lung Transplantation Recipients. ( 26833657 )
2016
18
Comparison of Initial Response of Nebulized Salbutamol and Adrenaline in Infants and young Children Admitted with Acute Bronchiolitis. ( 27892438 )
2016
19
Lung Clearance Index (LCI) in Patients with Bronchiolitis Obliterans: A Preliminary Report and Comparison to Cystic Fibrosis Patients. ( 27645685 )
2016
20
Pathology of Diacetyl and 2,3-Pentanedione Airway Lesions in a Rat Model of Obliterative Bronchiolitis. ( 27984136 )
2016
21
Spirometry States the Obvious: Recognizing Bronchiolitis Obliterans Syndrome Early after Hematopoietic Cell Transplantation. ( 27831809 )
2016
22
Viral Bronchiolitis in Children. ( 27144865 )
2016
23
Extracorporeal photopheresis as a new supportive therapy for bronchiolitis obliterans syndrome after allogeneic stem cell transplantation. ( 26726939 )
2016
24
Reduction of obliterative bronchiolitis (OB) by prolyl-hydroxylase-inhibitors activating hypoxia-inducible transcription factors in an experimental mouse model. ( 27590486 )
2016
25
Acute viral bronchiolitis and risk of asthma in schoolchildren: analysis of a Brazilian newborn cohort. ( 27665269 )
2016
26
Advancing our understanding of infant bronchiolitis through phenotyping and endotyping: Clinical and molecular approaches. ( 27192374 )
2016
27
Observational Study of Methotrexate in the Treatment of Bronchiolitis Obliterans Syndrome. ( 27931586 )
2016
28
Opening Pandora's Box: A Chest Radiograph in a 5-Month-Old With Bronchiolitis. ( 27609945 )
2016
29
Are leukotriene inhibitors useful for bronchiolitis? ( 28032855 )
2016
30
Economic evaluation of nasogastric versus intravenous hydration in infants with bronchiolitis. ( 28004493 )
2016
31
Impact of long-term treatment with inhaled corticosteroids and bronchodilators on lung function in a patient with post-infectious bronchiolitis obliterans. ( 27383939 )
2016
32
Nasal Airway Microbiota Profile and Severe Bronchiolitis in Infants: A Case-Control Study. ( 28005692 )
2016
33
Risk Factor and Clinical Outcome of Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation. ( 26847288 )
2016
34
Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review. ( 27200095 )
2016
35
More on Viral Bronchiolitis in Children. ( 27653587 )
2016
36
OC04 - A weaning plan for high flow nasal therapy (HFNT) in bronchiolitis - a nurse-led initiative. ( 27214418 )
2016
37
Hypoxemia is an independent predictor of bronchiolitis obliterans following respiratory adenoviral infection in children. ( 27722041 )
2016
38
Migrating persistent pulmonary consolidation in a child: A case of follicular bronchiolitis. ( 27640404 )
2016
39
Bronchiolitis and fecal flora. ( 27566801 )
2016
40
MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndromeTo the Editor. ( 27044533 )
2016
41
Rhinopharyngeal Retrograde Clearance Induces Less Respiratory Effort and Fewer Adverse Effects in Comparison With Nasopharyngeal Aspiration in Infants With Acute Viral Bronchiolitis. ( 27555618 )
2016
42
Constrictive Bronchiolitis: A Distinct Phenotype of Cystic Fibrosis Lung Disease? ( 27925783 )
2016
43
Hepatocyte growth factor enhances the inflammation-alleviating effect of umbilical cord-derived mesenchymal stromal cells in a bronchiolitis obliterans model. ( 26857230 )
2016
44
Diagnosing and treating respiratory syncytial virus bronchiolitis. ( 27552683 )
2016
45
Azithromycin for the Treatment of Obliterative Bronchiolitis after Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis. ( 27575542 )
2016
46
MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndrome. ( 26874429 )
2016
47
Diagnosis and management of bronchiolitis obliterans syndrome following lung or hematopoietic cell transplantation. ( 26950825 )
2016
48
Evaluating bronchodilator response in pediatric patients with post-infectious bronchiolitis obliterans: use of different criteria for identifying airway reversibility. ( 27383929 )
2016
49
Oxygen saturations targets in infants with bronchiolitis: Is 90% as effective as 94%? ( 27145519 )
2016
50
Bronchiolitis in young infants: is it a risk factor for recurrent wheezing in childhood? ( 27650524 )
2016

Variations for Bronchiolitis

Expression for Bronchiolitis

Search GEO for disease gene expression data for Bronchiolitis.

Pathways for Bronchiolitis

Pathways related to Bronchiolitis according to GeneCards Suite gene sharing:

(show top 50) (show all 75)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
14.03 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG
2
Show member pathways
13.97 CCL11 CCL3 CCL5 CD40LG CXCL8 IL10
3
Show member pathways
13.81 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG
4
Show member pathways
13.69 CCL11 CCL3 CCL5 CXCL8 IFNG IL10
5
Show member pathways
13.46 CCL11 CCL3 CCL5 CD40LG CXCL8 IL10
6
Show member pathways
13.43 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG
7
Show member pathways
13.39 CCL11 CCL3 CCL5 CD40LG CXCL8 IL10
8
Show member pathways
13.27 IFNG IL4 IL4R TLR10 TLR4 TLR6
9
Show member pathways
13.15 CCL5 CXCL8 IL6 MUC5B TLR10 TLR4
10
Show member pathways
13.09 CCL3 CCL5 CXCL8 IFNG IL10 IL6
11
Show member pathways
12.99 CCL11 CD40LG CXCL8 IFNG IL10 IL13
12
Show member pathways
12.97 CCL5 CXCL8 IFNG IL13 IL4 IL6
13
Show member pathways
12.82 CD40LG IL6 TLR10 TLR4 TLR6 TNF
14
Show member pathways
12.81 CD40LG IFNG IGHE IL10 IL4 IL4R
15
Show member pathways
12.8 IFNG IL10 IL13 IL4 IL4R IL5
16
Show member pathways
12.79 CCL5 CXCL8 IFNG IL6 TNF
17 12.72 CCL5 CD40LG IFNG IL10 IL4 TLR6
18
Show member pathways
12.68 CD40LG TLR10 TLR4 TLR6 TNF
19
Show member pathways
12.67 IGHE IL13 IL4 IL5 TNF
20
Show member pathways
12.62 CD40LG IFNG IL10 IL4 IL5 IL6
21
Show member pathways
12.48 CCL11 CXCL8 IFNG IL13 IL4 IL5
22
Show member pathways
12.46 CCL5 IFNG IL4 IL6 TNF
23
Show member pathways
12.45 CXCL8 IL6 TLR10 TLR4 TLR6 TNF
24
Show member pathways
12.44 CD40LG IFNG IL10 IL4 TLR4 TNF
25
Show member pathways
12.43 CCL11 IGHE IL4 IL4R
26
Show member pathways
12.43 IFNG IL10 IL13 IL4 IL4R IL5
27 12.42 IFNG IL10 IL6 TLR4 TLR6 TNF
28
Show member pathways
12.41 CXCL8 IFNG IL6 TLR4 TNF
29
Show member pathways
12.4 CCL11 CXCL8 IFNG IL4 IL6 TLR4
30 12.37 IFNG IL6 TLR10 TLR4 TLR6 TNF
31
Show member pathways
12.35 CXCL8 IFNG IL10 IL13 IL4 IL5
32 12.33 CXCL8 IL10 IL13 IL6 TNF
33 12.22 CXCL8 IFNG IL4 IL6 TLR4 TNF
34
Show member pathways
12.2 IL13 IL5 TLR10 TLR4 TLR6
35 12.2 IFNG IL10 IL4 IL5 IL6 TNF
36
Show member pathways
12.18 IFNG IL10 IL6 TLR10 TLR4 TLR6
37
Show member pathways
12.15 IFNG IL4 IL4R IL6 TLR10 TLR4
38
Show member pathways
12.12 CCL11 CCL3 CCL5 CXCL8
39 12.11 CXCL8 IFNG IL10 IL6 TLR4 TNF
40 12.08 IL4 IL4R IL5 IL6 TNF
41 12.08 CCL3 CCL5 CXCL8 IFNG IL6 TLR4
42 12.06 CCL3 CXCL8 IFNG IL6
43 12.03 CCL3 CXCL8 IFNG IL6 TLR4
44 12.03 CXCL8 IFNG IL13 IL4 IL5 IL6
45 12.01 CD40LG CXCL8 TLR4 TNF
46 12.01 CCL3 IFNG IL10 IL13 IL4 IL5
47
Show member pathways
11.99 CD40LG CXCL8 IFNG IL4 IL5 TNF
48 11.97 CCL11 CXCL8 IGHE IL10 IL13 IL4
49 11.96 CXCL8 IL10 IL6 TLR4 TNF
50 11.94 CD40LG IL10 IL4 IL5 IL6 TLR4

GO Terms for Bronchiolitis

Cellular components related to Bronchiolitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG
2 external side of plasma membrane GO:0009897 9.76 CD40LG IFNG IGHE IL13 IL4 IL6
3 extracellular space GO:0005615 9.5 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG

Biological processes related to Bronchiolitis according to GeneCards Suite gene sharing:

(show top 50) (show all 83)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.99 CD40LG IL6 TLR4 TNF
2 response to virus GO:0009615 9.97 CCL11 CCL5 IFNG TNF
3 cellular response to tumor necrosis factor GO:0071356 9.95 CCL11 CCL3 CCL5 CXCL8 IL6
4 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.95 CCL11 CCL3 CCL5 IL6 TLR4 TNF
5 movement of cell or subcellular component GO:0006928 9.94 CXCL8 IFNG IL13
6 positive regulation of protein kinase B signaling GO:0051897 9.94 CCL3 IL6 TNF
7 chemokine-mediated signaling pathway GO:0070098 9.94 CCL11 CCL3 CCL5 CXCL8
8 cellular response to organic cyclic compound GO:0071407 9.93 CCL3 CCL5 TNF
9 response to glucocorticoid GO:0051384 9.93 IL10 IL6 TNF
10 defense response to Gram-positive bacterium GO:0050830 9.93 IL6 RNASE3 TNF
11 B cell differentiation GO:0030183 9.93 CD40LG IL10 IL4
12 regulation of insulin secretion GO:0050796 9.92 CCL5 IFNG TNF
13 positive regulation of B cell activation GO:0050871 9.92 IGHE IL4 IL6
14 positive regulation of smooth muscle cell proliferation GO:0048661 9.92 CCL5 IL13 IL6 TNF
15 response to cytokine GO:0034097 9.91 CCL5 IL4 IL6
16 cellular response to interferon-gamma GO:0071346 9.91 CCL11 CCL3 CCL5
17 positive regulation of inflammatory response GO:0050729 9.91 CCL3 TLR10 TLR4
18 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.91 IL10 IL4 IL5 IL6 TNF
19 humoral immune response GO:0006959 9.9 IFNG IL6 TNF
20 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.9 CCL5 IFNG IL4 IL6
21 positive regulation of cell adhesion GO:0045785 9.89 CCL5 IFNG TNF
22 positive regulation of tumor necrosis factor production GO:0032760 9.89 CCL3 IFNG TLR4
23 immune response GO:0006955 9.89 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG
24 toll-like receptor signaling pathway GO:0002224 9.88 TLR10 TLR4 TLR6
25 positive regulation of interleukin-6 production GO:0032755 9.88 IL6 TLR4 TNF
26 protein kinase B signaling GO:0043491 9.87 CCL3 CCL5 TNF
27 positive regulation of nitric oxide biosynthetic process GO:0045429 9.87 IFNG IL6 TLR4 TNF
28 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.86 TLR10 TLR4 TLR6
29 monocyte chemotaxis GO:0002548 9.86 CCL11 CCL3 CCL5 IL6
30 negative regulation of endothelial cell apoptotic process GO:2000352 9.85 IL10 IL13 IL4
31 cellular response to interleukin-1 GO:0071347 9.85 CCL11 CCL3 CCL5 CXCL8 IL6
32 cellular response to lipopolysaccharide GO:0071222 9.85 CXCL8 IFNG IL10 IL6 TLR4 TNF
33 negative regulation of interleukin-6 production GO:0032715 9.84 IL10 TLR4 TNF
34 positive regulation of B cell proliferation GO:0030890 9.84 IL13 IL4 IL5 TLR4
35 positive regulation of interleukin-12 production GO:0032735 9.83 CD40LG IFNG TLR4
36 positive regulation of interleukin-10 production GO:0032733 9.83 CD40LG IL4 TLR4
37 negative regulation of osteoclast differentiation GO:0045671 9.83 CCL3 IL4 TLR4
38 neutrophil chemotaxis GO:0030593 9.83 CCL11 CCL3 CCL5 CXCL8 IFNG
39 positive regulation of JAK-STAT cascade GO:0046427 9.82 CCL5 IL5 IL6
40 positive regulation of chemokine production GO:0032722 9.81 IL6 TLR4 TNF
41 negative regulation of growth of symbiont in host GO:0044130 9.81 IFNG IL10 TNF
42 microglial cell activation GO:0001774 9.8 IL13 IL4 TLR6
43 lipopolysaccharide-mediated signaling pathway GO:0031663 9.8 CCL3 CCL5 TLR4 TNF
44 positive regulation of T cell proliferation GO:0042102 9.8 CCL5 CD40LG IFNG IL4 IL6
45 positive regulation of macrophage activation GO:0043032 9.79 IL10 IL13 IL4R
46 regulation of cytokine secretion GO:0050707 9.78 TLR10 TLR4 TLR6
47 positive regulation of chemokine biosynthetic process GO:0045080 9.77 IFNG IL4 TNF
48 T-helper 1 type immune response GO:0042088 9.76 TLR4 TLR6
49 negative regulation of interleukin-17 production GO:0032700 9.76 IFNG TLR4
50 positive regulation of mast cell degranulation GO:0043306 9.76 IL13 IL4 IL4R

Molecular functions related to Bronchiolitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.56 IL10 IL4 IL5 IL6
2 cytokine activity GO:0005125 9.4 CCL11 CCL3 CCL5 CD40LG CXCL8 IFNG
3 phospholipase activator activity GO:0016004 9.37 CCL3 CCL5
4 CCR5 chemokine receptor binding GO:0031730 9.32 CCL3 CCL5
5 chemokine activity GO:0008009 9.26 CCL11 CCL3 CCL5 CXCL8
6 CCR1 chemokine receptor binding GO:0031726 9.16 CCL3 CCL5

Sources for Bronchiolitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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