MCID: BRN012
MIFTS: 58

Bronchiolitis Obliterans malady

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Bronchiolitis Obliterans

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Aliases & Descriptions for Bronchiolitis Obliterans:

Name: Bronchiolitis Obliterans 35 11 48 50 39 13 68
Bronchiolitis Fibrosa Obliterans 11 68
Obliterative Bronchiolitis 11 48
 
Bronchiolitis, Exudative 68
Bronchiolitis Exudativa 11

Classifications:



External Ids:

Disease Ontology11 DOID:2799
MeSH39 D001989
SNOMED-CT62 40100001
NCIt45 C62580

Summaries for Bronchiolitis Obliterans

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NIH Rare Diseases:48 Bronchiolitis obliterans is an inflammatory condition that affects the lung's tiniest airways, the bronchioles. In affected people, the bronchioles may become damaged and inflamed leading to extensive scarring that blocks the airways. Signs and symptoms of the condition include a dry cough; shortness of breath; and/or fatigue and wheezing in the absence of a cold or asthma. Many different chemicals (such as nitrogen oxides, ammonia, welding fumes or food flavoring fumes) and respiratory infections can cause lung injury that leads to bronchiolitis obliterans. It can also be associated with rheumatoid arthritis and graft-versus-host disease following a lung or hematopoietic cell transplantation. While there is no way to reverse the disease, treatments are available that may stabilize or slow the progression. Another similarly named disease, bronchiolitis obliterans organizing pneumonia, is a completely different disease. Last updated: 11/1/2016

MalaCards based summary: Bronchiolitis Obliterans, also known as bronchiolitis fibrosa obliterans, is related to common variable immunodeficiency and evans' syndrome, and has symptoms including wheezing An important gene associated with Bronchiolitis Obliterans is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways are RXR and RAR heterodimerization with other nuclear receptor and IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. Affiliated tissues include lung, bone and bone marrow, and related mouse phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and liver/biliary system.

Disease Ontology:11 A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults.

Wikipedia:71 Bronchiolitis obliterans (BO) is a disease that results in obstruction of the smallest airways of the... more...

Related Diseases for Bronchiolitis Obliterans

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Diseases related to Bronchiolitis Obliterans via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 376)
idRelated DiseaseScoreTop Affiliating Genes
1common variable immunodeficiency30.2TIMP1, TNF
2evans' syndrome30.2CXCL8, IL10, TNF
3respiratory failure30.2IL10, IL6, TNF
4primary biliary cirrhosis30.0IL10, IL6, TNF
5adult respiratory distress syndrome30.0IL6, MMP9, TNF
6acute interstitial pneumonia30.0CXCL8, IL10
7melioidosis30.0IFNG, IL10, IL6
8cryoglobulinemia29.7CXCL8, IL10, IL6, TNF
9retroperitoneal fibrosis29.7IL10, IL6, TGFB1, TNF
10systemic lupus erythematosus29.6CXCR3, IFNG, IL10, IL6, TNF
11hepatitis b28.9CXCL8, GZMB, IFNG, IL10, TNF
12rheumatoid arthritis28.4CXCL8, IFNG, IL10, IL17A, IL6, MMP9
13asthma28.2CXCL8, IFNG, IL10, IL17A, IL6, MMP9
14malaria27.6CXCL8, CXCR3, IFNG, IL10, IL17A, IL6
15bronchiolitis obliterans with obstructive pulmonary disease12.1
16cryptogenic organizing pneumonia12.1
17bronchiolitis11.2
18pneumonia11.0
19piepkorn karp hickok syndrome10.6IL10, TNF
20baetz-greenwalt syndrome10.6IFNG, TNF
216q terminal deletion syndrome10.6IL10, TNF
22hematopoietic stem cell transplantation10.6
23parsonage turner syndrome10.6TGFB1, TNF
24autoimmune pancreatitis10.6IFNG, TNF
25myopathy-growth delay-intellectual disability-hypospadias syndrome10.6TGFB1, TNF
26rasmussen subacute encephalitis10.5CXCL8, IL17A
27corneal deposit10.5CXCL8, IL6
28eye accommodation disease10.5IFNG, IL10
29ameloblastic carcinoma10.5MMP8, MMP9
30tarsal tunnel syndrome10.5CXCL8, IL6
31oropharynx cancer10.5CXCL8, MMP9, TNF
32paralytic lagophthalmos10.5IL10, TNF
33aortic arch interruption10.5IL6, TNF
34papillary cystadenocarcinoma10.5IL10, TGFB1
35gonococcal synovitis10.5IFNG, MMP9, TNF
36cutaneous leishmaniasis10.5IL6, TNF
37exophthalmos10.5CXCL8, IFNG, TNF
38inner ear disease10.5CXCL8, IFNG, TNF
39secondary lacrimal atrophy10.5IFNG, TGFB1, TNF
40basidiobolomycosis10.5CXCL8, IL10, TNF
41nevus mucinosis10.5IL10, IL17A
42nonspecific interstitial pneumonia10.4CXCL8, IFNG, TGFB1
43maligant granulosa cell tumor of ovary10.4CXCL8, IL6, TNF
44perrault syndrome10.4MMP9, TGFB1, TNF
45graft-versus-host disease, protection against10.4IFNG, IL10, TNF
46rhizomelic chondrodysplasia punctata10.4IFNG, IL17A, TNF
47geotrichosis10.4CXCL8, IL10, TNF
48skin disease10.4CXCL8, IL6, TNF
49pediatric supratentorial ependymoma10.4CXCL8, IL10, TNF
50peanut allergy10.4IL10, TGFB1, TNF

Graphical network of the top 20 diseases related to Bronchiolitis Obliterans:



Diseases related to bronchiolitis obliterans

Symptoms & Phenotypes for Bronchiolitis Obliterans

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UMLS symptoms related to Bronchiolitis Obliterans:


wheezing

GenomeRNAi Phenotypes related to Bronchiolitis Obliterans according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00250-A-18.8CXCL8, GZMB, IL10, IL17A, TGFB1, TNF

MGI Mouse Phenotypes related to Bronchiolitis Obliterans according to GeneCards Suite gene sharing:

41 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.6IFNG, IL10, IL6, PDGFB, TGFB1, TNF
2MP:00053698.1IFNG, IL10, IL6, MMP9, PDGFB, TGFB1
3MP:00107718.0IFNG, IL10, IL6, MMP9, PDGFB, TGFB1
4MP:00053677.7CXCR3, IFNG, IL17A, IL6, MMP9, PDGFB
5MP:00053917.5IFNG, IL10, IL6, MMP7, MMP9, PDGFB
6MP:00053907.3IFNG, IL10, IL17A, IL6, MMP9, TGFB1
7MP:00053897.3IFNG, IL10, IL6, MMP9, PDGFB, TGFB1
8MP:00053817.0IFNG, IL10, IL17A, IL6, MMP7, MMP9
9MP:00053886.5CXCR3, IFNG, IL10, IL17A, IL6, MMP9
10MP:00020066.2CXCR3, IFNG, IL10, IL6, MMP7, MMP8
11MP:00053976.0CXCR3, IFNG, IL10, IL17A, IL6, MMP7
12MP:00053856.0CXCR3, IFNG, IL10, IL6, MMP7, MMP9
13MP:00053786.0IFNG, IL10, IL17A, IL6, MMP7, MMP9
14MP:00107685.8CXCR3, IFNG, IL10, IL17A, IL6, MMP7
15MP:00053875.6CXCR3, IFNG, IL10, IL17A, IL6, MMP7
16MP:00053765.4CXCR3, IFNG, IL10, IL17A, IL6, MMP7

Drugs & Therapeutics for Bronchiolitis Obliterans

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Drugs for Bronchiolitis Obliterans (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 117)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Miconazoleapproved, investigational, vet_approvedPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 1362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
2
Erythromycinapproved, vet_approvedPhase 495114-07-812560
Synonyms:
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
,10-dione
114-07-8
3''-O-demethylerythromycin
374700-25-1
45673_FLUKA
45674_FLUKA
79235-06-6
82343-12-2
A/T/S
AC-12744
AC1L1FIQ
AC1L1QK7
AC1L1ZUR
AC1O8PVA
AC1Q2UA1
AC1Q6O1S
AI3-50138
AR-1A4414
AR-1H0723
Abboticin
Abomacetin
Acneryne
Acnesol
Ak-Mycin
Ak-mycin
Akne Cordes Losung
Akne-Mycin
Akne-mycin (TN)
Aknederm Ery Gel
Aknemycin
Aknin
AustriaS
BB_NC-1332
BIDD:GT0017
BPBio1_000312
BSPBio_000282
BSPBio_002480
Benzamycin
Benzamycin Pak
Bristamycin
C-Solve-2
C01912
C37H67NO13
CCRIS 9078
CHEBI:42355
CHEMBL532
CID12560
CID3255
CID6713919
CID8233
D00140
DB00199
Del-Mycin
Derimer
Deripil
DivK1c_000294
DivK1c_000397
DivK1c_000702
Dotycin
Dumotrycin
E- mycin, Erycin, Robimysin
E-Base
E-Base (base)
E-Glades
E-Mycin
E-Mycin (base)
E-Solve 2
E0751
E0774_SIAL
E5389_SIGMA
E6376_SIAL
E7904_SIGMA
EINECS 204-040-1
EM
EMU
ERY
ERYC
ERYC (base)
ERYTHROMYCIN STEARATE
ETS
Emgel
Emu-V
Emu-Ve
Emuvin
Emycin
Endoeritrin
Erecin
Erimycin-T
Erisone
Eritomicina
Eritrocina
Eritromicina
Eritromicina [INN-Spanish]
Ermycin
Eros
Ery-B
Ery-Diolan
Ery-Sol
Ery-Tab
Ery-Tab (base)
Ery-maxin
Eryacne
Eryacnen
Eryc
Eryc (TN)
Eryc 125
Eryc Sprinkles
Eryc-125
Eryc-250
Erycen
Erycette
Erycin
Erycinum
Eryderm
Erydermer
Erygel
Erygel (TN)
Eryhexal
Erymax
Erymed
Erypar
Erysafe
Erytab
Erythra-Derm
Erythro
Erythro-Statin
Erythro-Teva
Erythrocin
Erythrocin Stearate
Erythroderm
Erythrogran
Erythroguent
Erythromast 36
Erythromid
Erythromycin
Erythromycin & VRC3375
Erythromycin (JP15/USP/INN)
 
Erythromycin A
Erythromycin A, T-Stat, Pantomicina, HSDB 3074, Erytab, DRG-0279
Erythromycin B
Erythromycin C
Erythromycin Lactate
Erythromycin Ointment
Erythromycin Stearate
Erythromycin [INN:BAN:JAN]
Erythromycin base
Erythromycin estolate
Erythromycin ethylsuccinate
Erythromycin glucoheptonate
Erythromycin intravenous
Erythromycin lactobionate
Erythromycin oxime
Erythromycin sodium lauryl sulfate
Erythromycin, compd. with monododecyl sulfate, sodium salt
Erythromycine
Erythromycine [INN-French]
Erythromycinum
Erythromycinum [INN-Latin]
Erytop
Erytrociclin
Ethril 250
HMS1568O04
HMS1920M04
HMS2091D05
HMS500O16
HSDB 3074
I06-0245
IDI1_000294
IDI1_000397
IDI1_000702
Ilocaps
Ilosone
Ilosone (estolate)
Iloticina
Ilotycin
Ilotycin Gluceptate
Ilotycin T.S
Ilotycin T.S.
Inderm
Inderm Gel
IndermRetcin
KBio1_000294
KBio1_000397
KBio1_000702
KBio2_000555
KBio2_001139
KBio2_003123
KBio2_003707
KBio2_005691
KBio2_006275
KBioGR_001175
KBioSS_000555
KBioSS_001139
KST-1A8261
Kesso-Mycin
LMPK04000006
LS-187077
LS-64648
Latotryd
Lederpax
MLS001066618
Mephamycin
Mercina
MolPort-000-772-161
MolPort-002-507-378
MolPort-003-933-429
N-Methylerythromycin A
NCGC00179619-01
NCI-C55674
NINDS_000294
NINDS_000397
NINDS_000702
NSC 55929
NSC55929
Oftalmolosa Cusi Eritromicina
Oftamolets
PCE Dispertab (base)
Paediathrocin
Pantoderm
Pantodrin
Pantomicina
Pce
Pce (TN)
Pfizer-e
Pharyngocin
Prestwick0_000151
Prestwick1_000151
Prestwick2_000151
Prestwick3_000151
Prestwick_205
Primacine
Propiocine
Proterytrin
R-P Mycin
Retcin
Robimycin
Romycin
SBB057401
SMP1_000119
SMR000544946
SPBio_000778
SPBio_001226
SPBio_002221
SPECTRUM1500280
STK249736
Sans-acne
Sansac
Serp-AFD
Skid Gel E
Spectrum2_000759
Spectrum2_001263
Spectrum4_000538
Spectrum5_001596
Spectrum_000115
Spectrum_000659
Staticin
Staticin (TN)
Stiemicyn
Stiemycin
Sulfuric acid, monododecyl ester, sodium salt, compd. with erythromycin
T-Stat
T-stat (TN)
Taimoxin-F
Theramycin Z
Tiloryth
Tiprocin
Torlamicina
UNII-63937KV33D
Udima Ery Gel
Wemid
Wyamycin S
adecane-2,10-dione (non-preferred name)
bmse000664
erythro
erythromycin
nchembio.285-comp13
érythromycine
3
AztreonamapprovedPhase 44478110-38-05362041, 5742832
Synonyms:
(Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid
2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid
2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
78110-38-0
AC-4330
AC1NX3U2
AZT
Ambap78110-38-0
Azactam
Aztreonam
Aztreonamum
Aztréonam
BIDD:GT0765
BPBio1_000121
BRD-K62607865-001-03-0
 
BSPBio_000109
CHEBI:161680
CHEMBL158
CID5742832
HMS1568F11
HMS2090K09
MolPort-003-886-345
Monobactam, SQ 26776, Squibb 26776, Aztreonam
NCGC00179656-01
NSC646279
Prestwick2_000185
Prestwick3_000185
Prestwick_914
Primbactam
S1505_Selleck
SQ-26776
[2S-[2alpha,3beta(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
aztreonam
4
AzithromycinapprovedPhase 4, Phase 3, Phase 2, Phase 133383905-01-555185, 53477736, 447043
Synonyms:
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*
121470-24-4
75199_FLUKA
83905-01-5
9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A
AC-16014
AC1L9KEG
Aritromicina
Azasite
Azenil
Azifast
Azigram
Azimakrol
Azithramycine
Azithromycin
Azithromycin & Tumor Necrosis Factor
Azithromycin (AIDS Initiative)
Azithromycin (anhydrous)
Azithromycin Dihydrate
Azithromycin Monohydrate
Azithromycin Sterile
Azithromycin dihydrate
Azithromycin plus Tumor Necrosis Factor
Azithromycine
Azithromycine [French]
Azithromycinum
Azithromycinum [Latin]
Azitrocin
Azitromax
Azitromicina
Azitromicina [Spanish]
Azitromin
Azythromycin
BIDD:GT0792
BRN 5387583
BSPBio_002285
Bio-0676
C38H72N2O12
CCRIS 1961
CHEBI:2955
CHEMBL529
CID447043
CP-62993
CP62,993
CPD000471864
DCH3
DRG-0104
 
DivK1c_000233
HMS1922G12
HMS2094M11
HMS500L15
HSDB 7205
Hemomycin
IDI1_000233
KBio1_000233
KBio2_000787
KBio2_003355
KBio2_005923
KBio3_001505
KBioGR_000731
KBioSS_000787
LS-1834
MLS001055353
MLS001066331
MLS001201763
MLS001304005
MLS001332499
MLS001332500
Misultina
MolPort-002-507-426
N,N-Dimethyl-4-amino-benzaldehyde
NCGC00090753-01
NCGC00090753-02
NINDS_000233
NSC643732
SAM002589961
SMR000471864
SPBio_001544
SPECTRUM1503679
Spectrum2_001582
Spectrum3_000653
Spectrum4_000186
Spectrum5_001867
Spectrum_000307
Sumamed
Tromix
UNII-JTE4MNN1MD
XZ-450
Z-Pak
ZIT
Zentavion
Zithromac
Zithromax
Zithromax IV
Zithromycin
Zitromax
Zitromax Avium 600
Zmas
Zmax
azithromycin
5
MechlorethamineapprovedPhase 4, Phase 337751-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
6
EverolimusapprovedPhase 4, Phase 31896159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
7
Tacrolimusapproved, investigationalPhase 4, Phase 3, Phase 1, Phase 21074104987-11-3445643, 439492
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
Anhydrous tacrolimus
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
 
FR900506
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus anhydrous
Tacrolimus hydrate
Tacrolimus, anhydrous
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
8
Prednisoneapproved, vet_approvedPhase 4, Phase 1, Phase 2135953-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
9
MontelukastapprovedPhase 4, Phase 2266158966-92-85281040
Synonyms:
(R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
(R-(e))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
1-((((1R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
1-[[[(1 R)-1-[3-[(1e)-2-(7-chloro-2-Quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid
151767-02-1 (sodium)
158966-92-8
2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
AC1NQXXW
Apxi toxin
BIDD:GT0394
Brondilat
Brondilat (TN)
C07482
C35H36ClNO3S
CHEBI:50730
CHEMBL787
CID5281040
 
D08229
DB00471
HMS2089D07
HSDB 7582
LS-173539
MK 0476
MK-0476
Montair
Montelukast
Montelukast (INN)
Montelukast [INN:BAN]
Montelukastum
Montélukast
Singulair
Singular
UNII-MHM278SD3E
montelukast
sodium 1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropylacetate
{1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid
10
AzathioprineapprovedPhase 4165446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
HMS1920E17
 
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
11
Sirolimusapproved, investigationalPhase 4, Phase 3189653123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
12
MacitentanapprovedPhase 433441798-33-0
Synonyms:
 
Macitentanum
13
Ergocalciferolapproved, nutraceuticalPhase 4123250-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
14Antifungal AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 13615
15Antirheumatic AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 110627
16Immunosuppressive AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 112770
17Calcineurin InhibitorsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 11597
18Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 121402
19Antibiotics, AntitubercularPhase 4, Phase 36972
20Anti-Asthmatic AgentsPhase 4, Phase 23369
21Anti-Inflammatory AgentsPhase 4, Phase 2, Phase 3, Phase 110355
22AntimetabolitesPhase 411774
23Trace ElementsPhase 45802
24Gastrointestinal AgentsPhase 4, Phase 2, Phase 18109
25Erythromycin EstolatePhase 495
26Erythromycin EthylsuccinatePhase 495
27Erythromycin stearatePhase 495
28Antimetabolites, AntineoplasticPhase 47171
29Antineoplastic Agents, HormonalPhase 4, Phase 25407
30ErgocalciferolsPhase 41232
31Hormone AntagonistsPhase 4, Phase 2, Phase 112778
32Bone Density Conservation AgentsPhase 43266
33HormonesPhase 4, Phase 2, Phase 113979
34glucocorticoidsPhase 4, Phase 2, Phase 14920
35Leukotriene AntagonistsPhase 4, Phase 2291
36Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 2, Phase 112767
37MicronutrientsPhase 45802
38Adrenergic AgentsPhase 4, Phase 25140
39vitamin dPhase 41653
40BromidesPhase 4606
41Bronchodilator AgentsPhase 4, Phase 22856
42Cholinergic AgentsPhase 43846
43Autonomic AgentsPhase 4, Phase 29774
44AlbuterolPhase 4408
45Adrenergic AgonistsPhase 4, Phase 22877
46Adrenergic beta-2 Receptor AgonistsPhase 4, Phase 2925
47Adrenergic beta-AgonistsPhase 4, Phase 21640
48Cholinergic AntagonistsPhase 41658
49Neurotransmitter AgentsPhase 4, Phase 217734
50Anti-Bacterial AgentsPhase 4, Phase 310884

Interventional clinical trials:

(show top 50)    (show all 90)
idNameStatusNCT IDPhase
1Vitamin D in Bronchiolitis Obliterans SyndromeCompletedNCT01212406Phase 4
2Montelukast in Bronchiolitis Obliterans SyndromeCompletedNCT01211509Phase 4
3Bronchodilator Responsiveness in Obliterative BronchiolitisCompletedNCT01112241Phase 4
4Azithromycin in Bronchiolitis Obliterans SyndromeCompletedNCT01009619Phase 4
5Safety Study of Aztreonam Lysine for Inhalation (AZLI) in the Treatment of Early Bronchiolitis Obliterans Syndrome (BOS)CompletedNCT01469364Phase 4
6Use of Erythromycin in Mustard-Induced BronchiolitisCompletedNCT00367419Phase 4
7Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung TransplantationCompletedNCT01109160Phase 4
8Comparison of Sirolimus and Azathioprine in Lung TransplantationCompletedNCT00321906Phase 4
9Macitentan in the Treatment of Organ Rejection After Lung TransplantationNot yet recruitingNCT02893176Phase 4
10Tacrolimus Versus Cyclosporine for Immunosuppression After Lung TransplantationCompletedNCT01429844Phase 3
11Study of Cyclosporine Inhalation Solution (CIS) in Improving Bronchiolitis Obliterans Syndrome-Free Survival Following Lung TransplantationCompletedNCT00755781Phase 3
12Study Comparing Simulect Plus Standard Immunosuppression to Standard Immunosuppression Alone for the Prevention of Acute Rejection and Bronchiolitis Obliterans in Lung TransplantCompletedNCT00188825Phase 3
13Use of Clarithromycin in Mustard-Induced BronchiolitisCompletedNCT00381147Phase 3
14Immunosuppressive Therapy With Certican (Everolimus) After Lung TransplantationCompletedNCT00402532Phase 3
15European Trial of Pirfenidone in BOS, A European Multi-center StudyRecruitingNCT02262299Phase 2, Phase 3
16Bronchopulmonary Function in Response to Azithromycin Treatment for Chronic Lung Disease in HIV-infected ChildrenRecruitingNCT02426112Phase 3
17Efficacy of Azithromycin to Prevent Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell TransplantationActive, not recruitingNCT01959100Phase 3
18Efficacy of Everolimus in Combination With Specific Standard Immunosuppressive Regimen Lung Transplant RecipientsActive, not recruitingNCT01404325Phase 3
19Long-term Safety Follow-up Study in the Prevention of Bronchiolitis Obliterans Syndrome (BOS)TerminatedNCT01439958Phase 3
20L-CsA in the Prevention of Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant (LT) PatientsTerminatedNCT01334892Phase 2, Phase 3
21CIS001 Extension Study of Cyclosporine Inhalation SolutionTerminatedNCT00938236Phase 3
22Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD)TerminatedNCT00089141Phase 3
23A Phase II Trial on Treatment of Steroid-refractory Bronchiolitis Obliterans With Interferon Gamma 1b After Allogeneic SCTUnknown statusNCT01639261Phase 2
24Study of Rituximab in Patients With Steroid-Refractory Chronic Graft-Versus-Host DiseaseUnknown statusNCT00472225Phase 2
25Targeted Therapy of Bronchiolitis Obliterans SyndromeCompletedNCT01307462Phase 2
26Inhaled BUDESONIDE/FORMOTEROL in Bronchiolitis Obliterans Following Stem Cell TransplantationCompletedNCT01560689Phase 2
27Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant RecipientsCompletedNCT01650545Phase 1, Phase 2
28Prospective Evaluation of the Efficacy of Budesonide/Formoterol in Bronchiolitis Obliterans in AHSCTCompletedNCT00624754Phase 2
29Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell TransplantCompletedNCT00141726Phase 2
30Etanercept for Non-Infectious Lung Injury Following Bone Marrow TransplantationCompletedNCT00029328Phase 1, Phase 2
31Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis ObliteransRecruitingNCT01287078Phase 2
32Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis ObliteransRecruitingNCT01273207Phase 2
33AZD9668, an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell TransplantationRecruitingNCT02669251Phase 1, Phase 2
34Prospective Study for Transplant Optimization Using Functional Imaging (TROFI)RecruitingNCT02488304Phase 2
35Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell DiseaseRecruitingNCT02960503Phase 1, Phase 2
36Study to Evaluate the Safety and Efficacy of Intravenous Glassia® Treatment in Lung TransplantationRecruitingNCT02614872Phase 2
37Montelukast to Treat Bronchiolitis ObliteransActive, not recruitingNCT00656058Phase 2
38A Proposal to Test the Efficacy and Tolerability of Bortezomib in Pulmonary Chronic GVHDActive, not recruitingNCT01163786Phase 2
39MSC for Treatment of Interstitial Lung Disease After Allo-HSCTActive, not recruitingNCT02543073Phase 1, Phase 2
40Trial of Bone-marrow Derived Mesenchymal Stromal Cells (MSC) for New Onset Chronic Lung Allograft DysfunctionNot yet recruitingNCT02709343Phase 2
41Steroids, Azithromycin, Montelukast, and Symbicort (SAMS) for Viral Respiratory Tract Infection Post AllotransplantSuspendedNCT01432080Phase 2
42Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant SuitabilitySuspendedNCT01615484Phase 2
43A Study to Evaluate the Potential of Mesenchymal Stromal Cells to Treat Obliterative Bronchiolitis After Lung TransplantationCompletedNCT01175655Phase 1
44Mesenchymal Stem Cell Therapy for Lung RejectionActive, not recruitingNCT02181712Phase 1
45Characterization of Bronchiolitis-obliterans Syndrome (BOS) Following Lung TransplantationUnknown statusNCT00774449
46Dry Powder Inhalation of Cyclosporine A in Lung Transplant Patients With Bronchiolitis Obliterans SyndromeUnknown statusNCT00378677Early Phase 1
47Immune Mechanisms of Rejection in Human Lung AllograftsUnknown statusNCT00861900
48Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory DiseaseUnknown statusNCT00163696
49Clinical Status and Bronchial Inflammation in Patients With Bronchiolitis ObliteransCompletedNCT01327248
50Effectiveness of Azithromycin Therapy in Improvement of Symptoms and Lung Function in Patients With Bronchiolitis Obliterans After Bone Marrow TransplantationCompletedNCT00563251

Search NIH Clinical Center for Bronchiolitis Obliterans

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Bronchiolitis Obliterans cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Bronchiolitis Obliterans:
Mesenchymal stem cells for obliterative bronchiolitis
Embryonic/Adult Cultured Cells Related to Bronchiolitis Obliterans:
Bone marrow-derived mesenchymal stem cells (family)


Cochrane evidence based reviews: bronchiolitis obliterans

Genetic Tests for Bronchiolitis Obliterans

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Anatomical Context for Bronchiolitis Obliterans

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MalaCards organs/tissues related to Bronchiolitis Obliterans:

36
Lung, Bone, Bone marrow, Breast, Heart, Neutrophil, T cells

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Bronchiolitis Obliterans:
id TissueAnatomical CompartmentCell Relevance
1 LungRespiratory BronchiolesCilliated Cells Potential therapeutic candidate, affected by disease

Publications for Bronchiolitis Obliterans

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Articles related to Bronchiolitis Obliterans:

(show top 50)    (show all 811)
idTitleAuthorsYear
1
Bronchiolitis obliterans syndrome in adults after allogeneic stem cell transplantation-pathophysiology, diagnostics and treatment. (28052713)
2017
2
Respiratory reactance in children aged three to fiveA years with postinfectious bronchiolitis obliterans is higher than in those with asthma. (27743492)
2017
3
An autopsy case of bronchiolitis obliterans as a previously unrecognized adverse event of afatinib treatment. (28012496)
2017
4
Imatinib ameliorates bronchiolitis obliterans via inhibition of fibrocyte migration and differentiation. (27388852)
2016
5
Impaired Capacity of Fibroblasts to Support Airway Epithelial Progenitors in Bronchiolitis Obliterans Syndrome. (27569228)
2016
6
Extracorporeal photopheresis as a new supportive therapy for bronchiolitis obliterans syndrome after allogeneic stem cell transplantation. (26726939)
2016
7
Diagnostic value of antineutrophil cytoplasmic antibodies in children with bronchiolitis obliterans. (27293851)
2016
8
Diagnosis and management of bronchiolitis obliterans syndrome following lung or hematopoietic cell transplantation. (26950825)
2016
9
Bronchiolitis obliterans organizing pneumonia associated with achalasia: A case report. (27408784)
2016
10
Phenytoin induced Steven-Johnson syndrome and bronchiolitis obliterans - case report and review of literature. (27222786)
2016
11
Rescue alemtuzumab for refractory acute cellular rejection and bronchiolitis obliterans syndrome after lung transplantation. (28008661)
2016
12
Advances in Understanding Bronchiolitis Obliterans after lung transplantation. (27212132)
2016
13
Bronchiolitis obliterans following hematopoietic stem cell transplantation: Importance of expiratory computed tomography. (27745931)
2016
14
Hypoxemia is an independent predictor of bronchiolitis obliterans following respiratory adenoviral infection in children. (27722041)
2016
15
Identification of miRNAs Potentially Involved in Bronchiolitis Obliterans Syndrome: A Computational Study. (27564214)
2016
16
Epiplakin Is a Paraneoplastic Pemphigus Autoantigen and Related to Bronchiolitis Obliterans in Japanese Patients. (26802236)
2016
17
Parametric Response Mapping of Bronchiolitis Obliterans Syndrome Progression After Lung Transplantation. (27367568)
2016
18
Therapeutic effect of budesonide/formoterol, montelukast and N-acetylcysteine for bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. (27229850)
2016
19
Evaluating bronchodilator response in pediatric patients with post-infectious bronchiolitis obliterans: use of different criteria for identifying airway reversibility. (27383929)
2016
20
Impact of long-term treatment with inhaled corticosteroids and bronchodilators on lung function in a patient with post-infectious bronchiolitis obliterans. (27383939)
2016
21
Lung Clearance Index (LCI) in Patients with Bronchiolitis Obliterans: A Preliminary Report and Comparison to Cystic Fibrosis Patients. (27645685)
2016
22
MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndromeTo the Editor. (27044533)
2016
23
Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review. (27200095)
2016
24
Long Term Follow-Up of Sulfur Mustard Related Bronchiolitis Obliterans Treatment. (27832694)
2016
25
Spirometry States the Obvious: Recognizing Bronchiolitis Obliterans Syndrome Early after Hematopoietic Cell Transplantation. (27831809)
2016
26
Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplantation. (27513368)
2016
27
Bronchiolitis Obliterans: Pleading for a Pragmatic Approach. (26802324)
2016
28
Prevention of bronchiolitis obliterans-the realization of a hope? (27667135)
2016
29
How I treat bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. (27856461)
2016
30
LPS-Responsive Beige-Like Anchor Gene Mutation Associated With Possible Bronchiolitis Obliterans Organizing Pneumonia Associated With Hypogammaglobulinemia and Normal IgM Phenotype and Low Number of B Cells. (27888588)
2016
31
Short-Term Variation of Lung Function and Airway Inflammation in Children and Adolescents with Bronchiolitis Obliterans. (27325047)
2016
32
Early outcomes of lung transplantation for bronchiolitis obliterans syndrome after allogeneic haematopoietic stem cell transplantation: a single-centre experience. (27481680)
2016
33
Observational Study of Methotrexate in the Treatment of Bronchiolitis Obliterans Syndrome. (27931586)
2016
34
Bronchiolitis Obliterans Syndrome (BOS) Following Lung Transplant. (27248598)
2016
35
The Impact of Alemtuzumab and Basiliximab Induction on Patient Survival and Time to Bronchiolitis Obliterans Syndrome in Double Lung Transplantation Recipients. (26833657)
2016
36
MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndrome. (26874429)
2016
37
Non-paraneoplastic autoimmune subepidermal bullous disease associated with fatal bronchiolitis obliterans. (27914107)
2016
38
Risk Factor and Clinical Outcome of Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation. (26847288)
2016
39
Bronchiolitis obliterans organising pneumonia associated with anticonvulsant hypersensitivity syndrome induced by lamotrigine. (26825933)
2016
40
HMGB1 exacerbates bronchiolitis obliterans syndrome via RAGE/NF-I_B/HPSE signaling to enhance latent TGF-I^ release from ECM. (27347307)
2016
41
Hepatocyte growth factor enhances the inflammation-alleviating effect of umbilical cord-derived mesenchymal stromal cells in a bronchiolitis obliterans model. (26857230)
2016
42
Proteomic characterization reveals that MMP-3 correlates with bronchiolitis obliterans syndrome following allogeneic hematopoietic cell and lung transplantation. (26887344)
2016
43
Differences of airway dimensions between patients with and without bronchiolitis obliterans syndrome after lung transplantation-Computer-assisted quantification of computed tomography. (27423681)
2016
44
Infections and neutrophils in the pathogenesis of bronchiolitis obliterans syndrome in children after allogeneic stem cell transplantation. (26918734)
2016
45
The Lymphatic Phenotype of Lung Allografts in Patients With Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome. (27163544)
2016
46
Acute graft-versus-host disease and bronchiolitis obliterans after autologous stem cell transplantation in a patient with multiple myeloma. (26185631)
2015
47
Pulmonary hypertension associated with bronchiolitis obliterans after hematopoietic stem cell transplantation. (26479977)
2015
48
Local Origin of Mesenchymal Cells in a Murine Orthotopic Lung Transplantation Model of Bronchiolitis Obliterans. (25848843)
2015
49
Bronchiolitis obliterans syndrome due to donor-specific HLA-antibodies. (26204790)
2015
50
Influence of human leukocyte antigen mismatching on bronchiolitis obliterans syndrome in lung transplantation. (26496787)
2015

Variations for Bronchiolitis Obliterans

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Expression for genes affiliated with Bronchiolitis Obliterans

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Search GEO for disease gene expression data for Bronchiolitis Obliterans.

Pathways for genes affiliated with Bronchiolitis Obliterans

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Pathways related to Bronchiolitis Obliterans according to GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idSuper pathwaysScoreTop Affiliating Genes
19.8TGFB1, TNF
29.7IL6, TGFB1
3
Show member pathways
9.5CXCL8, IFNG, TNF
49.4CXCL8, IL6, TNF
59.4IL6, PDGFB, TGFB1
69.4CXCL8, IFNG, IL6
7
Show member pathways
9.4CXCL8, IFNG, IL6
89.4CXCL8, IFNG, IL6
99.4IFNG, TGFB1, TNF
109.3IL10, IL6, TNF
119.3CXCL8, IL6, MMP9
129.3CXCL8, IL6, MMP9
139.3IFNG, IL10, IL6
149.2IFNG, IL6, TNF
159.1IL6, MMP9, TNF
169.1IL6, MMP9, TNF
179.1MMP7, MMP9, TGFB1
189.1CXCL8, IL6, TGFB1, TNF
19
Show member pathways
9.1GZMB, IFNG, TNF
209.1CXCL8, IL10, IL6, TNF
219.1CXCL8, IL10, IL6, TNF
229.1CXCL8, IFNG, IL6, TGFB1
23
Show member pathways
9.0IFNG, IL10, TGFB1, TNF
249.0IL6, PDGFB, TGFB1, TNF
25
Show member pathways
9.0CXCL8, IFNG, IL6, TNF
269.0CXCL8, IFNG, IL6, TNF
27
Show member pathways
9.0CXCL8, IFNG, IL6, TNF
289.0IL10, IL6, TGFB1, TNF
298.9IFNG, IL10, IL6, TNF
308.9IFNG, IL10, IL6, TNF
318.8CXCL8, IL10, IL17A, IL6, TNF
328.8IFNG, IL6, TIMP1
338.7GZMB, IFNG, IL10, TNF
348.6CXCL8, IL6, MMP9, PDGFB, TGFB1
358.6CXCL8, GZMB, IL6, MMP9
368.6IL6, PDGFB, TGFB1, TIMP1
378.6IFNG, IL10, IL6, TGFB1, TNF
388.6IFNG, IL10, IL6, TGFB1, TNF
398.6IFNG, IL10, IL6, TGFB1, TNF
408.4CXCL8, IFNG, IL17A, IL6, TGFB1, TNF
41
Show member pathways
8.4GZMB, IFNG, IL17A, IL6, TGFB1
42
Show member pathways
8.4CXCL8, IFNG, IL10, IL17A, IL6, TNF
43
Show member pathways
8.4GZMB, IFNG, IL10, TGFB1, TNF
448.4CXCL8, MMP7, MMP9, TIMP1
458.3CXCL8, IFNG, IL10, IL6, TGFB1, TNF
468.3CXCL8, IFNG, IL10, IL6, TGFB1, TNF
47
Show member pathways
8.3IFNG, IL10, IL17A, IL6, TGFB1, TNF
48
Show member pathways
8.3IFNG, IL10, IL17A, IL6, TGFB1, TNF
49
Show member pathways
8.3MMP7, MMP9, TGFB1, TIMP1
508.2CXCR3, GZMB, IFNG, IL10, IL17A, TNF

GO Terms for genes affiliated with Bronchiolitis Obliterans

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Cellular components related to Bronchiolitis Obliterans according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.7PDGFB, TGFB1, TIMP1
2external side of plasma membraneGO:00098979.5CXCR3, IFNG, IL17A, IL6, TNF
3cell surfaceGO:00099869.5CXCR3, MMP7, PDGFB, TGFB1, TNF
4proteinaceous extracellular matrixGO:00055788.0MMP7, MMP8, MMP9, TGFB1, TIMP1
5extracellular regionGO:00055766.7CXCL8, IFNG, IL17A, IL6, MMP7, MMP8
6extracellular spaceGO:00056156.0CXCL8, IFNG, IL10, IL17A, IL6, MMP7

Biological processes related to Bronchiolitis Obliterans according to GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chemotaxisGO:005092110.6PDGFB, TGFB1
2positive regulation of interleukin-23 productionGO:003274710.6IFNG, IL17A
3positive regulation of mononuclear cell migrationGO:007167710.5TGFB1, TNF
4negative regulation of cytokine secretion involved in immune responseGO:000274010.5IL10, TNF
5negative regulation of interleukin-17 productionGO:003270010.5IFNG, TGFB1
6response to molecule of bacterial originGO:000223710.5CXCL8, IL10
7positive regulation of MHC class II biosynthetic processGO:004534810.5IFNG, IL10
8cellular response to hepatocyte growth factor stimulusGO:003572910.5IL10, IL6
9positive regulation of calcidiol 1-monooxygenase activityGO:006055910.5IFNG, TNF
10positive regulation of chemokine biosynthetic processGO:004508010.5IFNG, TNF
11receptor biosynthetic processGO:003280010.4IL10, TNF
12epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.4IL6, TNF
13negative regulation of lipid storageGO:001088810.4IL6, TNF
14neutrophil apoptotic processGO:000178110.4IFNG, IL6
15positive regulation of vitamin D biosynthetic processGO:006055710.4IFNG, TNF
16movement of cell or subcellular componentGO:000692810.4CXCL8, CXCR3, IFNG
17cellular response to interleukin-1GO:007134710.3CXCL8, IL17A, IL6
18positive regulation of vascular smooth muscle cell proliferationGO:190470710.3MMP9, PDGFB
19negative regulation of T cell proliferationGO:004213010.3IL10, SCGB1A1, TGFB1
20positive regulation of MAP kinase activityGO:004340610.2PDGFB, TGFB1, TNF
21positive regulation of osteoclast differentiationGO:004567210.2IFNG, IL17A, TNF
22cell growthGO:001604910.2IL6, PDGFB, TGFB1
23extrinsic apoptotic signaling pathwayGO:009719110.2IFNG, TGFB1, TNF
24positive regulation of peptidyl-tyrosine phosphorylationGO:005073110.2IL6, PDGFB, TGFB1
25negative regulation of growth of symbiont in hostGO:004413010.1IFNG, IL10, TNF
26cell activationGO:000177510.1TGFB1, TIMP1
27negative regulation of fat cell differentiationGO:004559910.1IL6, TGFB1, TNF
28positive regulation of smooth muscle cell proliferationGO:004866110.1IL6, PDGFB, TNF
29negative regulation of membrane protein ectodomain proteolysisGO:005104510.1IL10, TIMP1
30positive regulation of peptidyl-serine phosphorylationGO:003313810.1IL6, TGFB1, TNF
31positive regulation of protein kinase B signalingGO:005189710.1IL6, TGFB1, TNF
32defense response to protozoanGO:004283210.1IFNG, IL10, IL6
33protein import into nucleus, translocationGO:000006010.1IFNG, TGFB1, TNF
34positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.1IL10, IL6, TNF
35humoral immune responseGO:000695910.0IFNG, IL6, TNF
36positive regulation of nitric oxide biosynthetic processGO:004542910.0IFNG, IL6, TNF
37response to insulinGO:003286810.0IL10, IL6, PDGFB
38collagen catabolic processGO:00305749.9MMP7, MMP8, MMP9
39response to woundingGO:00096119.9IL6, PDGFB, TGFB1
40negative regulation of gene expressionGO:00106299.9IFNG, PDGFB, TGFB1, TNF
41platelet degranulationGO:00025769.8PDGFB, TGFB1, TIMP1
42response to glucocorticoidGO:00513849.7IL10, IL6, SCGB1A1, TNF
43response to cytokineGO:00340979.6IL6, SCGB1A1, TIMP1
44cellular response to lipopolysaccharideGO:00712229.5CXCL8, IFNG, IL10, IL6, TNF
45positive regulation of gene expressionGO:00106289.4IFNG, IL6, PDGFB, TGFB1, TNF
46positive regulation of apoptotic processGO:00430659.2IFNG, IL6, MMP9, TGFB1, TNF
47extracellular matrix disassemblyGO:00226179.1MMP7, MMP8, MMP9, TIMP1
48positive regulation of transcription from RNA polymerase II promoterGO:00459449.0IFNG, IL10, IL17A, IL6, TGFB1, TNF
49response to drugGO:00424939.0IFNG, IL10, IL6, PDGFB, SCGB1A1, TGFB1
50inflammatory responseGO:00069549.0CXCL8, CXCR3, IL10, IL17A, IL6, TGFB1

Molecular functions related to Bronchiolitis Obliterans according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1metalloendopeptidase activityGO:00042229.8MMP7, MMP8, MMP9
2growth factor activityGO:00080838.9IL10, IL6, PDGFB, TGFB1, TIMP1
3serine-type endopeptidase activityGO:00042528.5GZMB, MMP7, MMP8, MMP9
4cytokine activityGO:00051258.2IFNG, IL10, IL17A, IL6, TGFB1, TIMP1

Sources for Bronchiolitis Obliterans

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet