Aliases & Classifications for Bronchitis

MalaCards integrated aliases for Bronchitis:

Name: Bronchitis 12 3 41 14 69 59
Chronic Bronchitis 12 72 28 40
Acute Bronchitis 12 40 69 59
Bronchitis, Chronic 72 41 69
Chest Cold 12 3
Acute Lower Respiratory Tract Infection 69
Acute Bronchitis and Bronchiolitis 12
Lower Respiratory Tract Infection 69
Recurrent Wheezy Bronchitis 12
Ci - Chest Infection 12
Bronchitis Chronic 51
Chest Infection 12

Classifications:



Summaries for Bronchitis

MedlinePlus : 40 Bronchitis is an inflammation of the bronchial tubes, the airways that carry air to your lungs. It causes a cough that often brings up mucus. It can also cause shortness of breath, wheezing, a low fever, and chest tightness. There are two main types of bronchitis: acute and chronic. Most cases of acute bronchitis get better within several days. But your cough can last for several weeks after the infection is gone. The same viruses that cause colds and the flu often cause acute bronchitis. These viruses spread through the air when people cough, or though physical contact (for example, on unwashed hands). Being exposed to tobacco smoke, air pollution, dusts, vapors, and fumes can also cause acute bronchitis. Less often, bacteria can also cause acute bronchitis. To diagnose acute bronchitis, your health care provider will ask about your symptoms and listen to your breathing. You may also have other tests. Treatments include rest, fluids, and aspirin (for adults) or acetaminophen to treat fever. A humidifier or steam can also help. You may need inhaled medicine to open your airways if you are wheezing. Antibiotics won't help if the cause is viral. You may get antibiotics if the cause is bacterial. NIH: National Heart, Lung, and Blood Institute

MalaCards based summary : Bronchitis, also known as chronic bronchitis, is related to pulmonary disease, chronic obstructive and bronchial disease, and has symptoms including cough, shortness of breath and low fever. An important gene associated with Bronchitis is ELANE (Elastase, Neutrophil Expressed), and among its related pathways/superpathways are Innate Immune System and Allograft rejection. The drugs Augmentin and Avelox I.V. have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and skin, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The disease has symptom cough with mucus, has symptom shortness of breath, has symptom low fever and has symptom chest tightness.

PubMed Health : 59
About acute bronchitis: In acute bronchitis, the lower airways (bronchi) are temporarily inflamed. The inflammation is usually caused by cold viruses, so it often occurs together with other symptoms of a cold.Acute bronchitis causes a cough which might not go away for a while, even after the cold has gone away. Although the cough may be unpleasant and persistent, in otherwise healthy people it usually isn’t anything serious. The symptoms then go away on their own after a few weeks. Treatment with medication usually isn’t necessary. Some medications may help relieve the symptoms a bit.

Wikipedia : 72 Bronchitis is inflammation of the bronchi (large and medium-sized airways) in the lungs. Symptoms... more...

Related Diseases for Bronchitis

Diseases related to Bronchitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 355)
# Related Disease Score Top Affiliating Genes
1 pulmonary disease, chronic obstructive 32.1 CXCL8 ELANE RNASE3 SERPINA1 TNF
2 bronchial disease 31.1 CCL11 CXCL8 ELANE IL5 RNASE3 TAC1
3 cystic fibrosis 30.7 CFTR CXCL8 ELANE MPO RNASE3 SERPINA1
4 sinusitis 30.3 CFTR CXCL8 IL5 RNASE3
5 pulmonary emphysema 30.2 ELANE SERPINA1 SERPINB1
6 pulmonary eosinophilia 30.2 CCL11 IL5 RNASE3
7 status asthmaticus 30.1 CXCL8 ELANE IL5 RNASE3
8 chronic eosinophilic pneumonia 30.0 CCL11 IL5 RNASE3
9 farmer's lung 30.0 CD79A ELANE TNF
10 eosinophilic pneumonia 30.0 CCL11 IL5 RNASE3
11 bronchiectasis 30.0 CFTR CXCL8 ELANE MPO SERPINA1
12 acute respiratory distress syndrome 29.9 CXCL8 ELANE TNF
13 pyelonephritis 29.8 ALB CXCL8 TNF
14 common cold 29.8 ALB CCL11 CXCL8 IL5 RNASE3
15 rhinitis 29.7 CCL11 CXCL8 IL5 RNASE3 VIP
16 eosinophilic gastroenteritis 29.7 ALB CCL11 IL5 RNASE3
17 respiratory failure 29.6 ALB CXCL8 ELANE TNF
18 pneumonia 29.5 CCL11 CD40LG CXCL8 ELANE IL5 MPO
19 ostertagiasis 29.5 ALB CD79A
20 maxillary sinusitis 29.4 CD79A MPO RNASE3
21 protein-losing enteropathy 29.4 ALB CD79A SERPINA1
22 bronchiolitis 29.4 CCL11 CD40LG CXCL8 IL5 RNASE3 TNF
23 allergic rhinitis 29.4 CCL11 CXCL8 IL5 MPO RNASE3 VIP
24 gastroenteritis 29.3 ALB CCL11 CXCL8 IL5 RNASE3 TNF
25 strongyloidiasis 29.3 CCL11 CD79A IL5
26 bronchopneumonia 29.3 CD40LG CD79A ELANE MPO
27 dermatitis, atopic 29.3 CCL11 CXCL8 IL5 RNASE3 TNF VIP
28 tonsillitis 29.2 CD79A CXCL8 TNF
29 byssinosis 29.2 CD40LG CD79A SERPINA1
30 aspergillosis 29.1 CD79A CFTR ELANE IL5
31 glomerulonephritis 28.7 ALB CD40LG CD79A MPO
32 lung disease 28.5 CFTR CXCL8 ELANE IL5 MPO SERPINA1
33 otitis media 27.9 ALB CCL11 CD40LG CD79A CXCL8 RNASE3
34 asthma 27.6 CCL11 CD40LG CD79A CFTR CXCL8 ELANE
35 plastic bronchitis 12.5
36 lung cancer 11.1
37 agammaglobulinemia, x-linked 10.8
38 ciliary dyskinesia, primary, 7 10.8
39 severe combined immunodeficiency 10.8
40 selective igm deficiency disease 10.8
41 chronic laryngitis 10.8
42 actinobacillosis 10.8
43 agammaglobulinemia, non-bruton type 10.8
44 parainfluenza virus type 3 10.8
45 autoimmune inner ear disease 10.6 MPO TNF
46 inflammatory diarrhea 10.6 CXCL8 MPO
47 loeffler endocarditis 10.6 IL5 RNASE3
48 bagassosis 10.5 CXCL8 IL5
49 pemphigoid gestationis 10.5 CCL11 IL5
50 wells syndrome 10.5 CXCL8 IL5 RNASE3

Comorbidity relations with Bronchitis via Phenotypic Disease Network (PDN): (show top 50) (show all 130)


Acquired Polycythemia Active Peptic Ulcer Disease
Acute Conjunctivitis Acute Cor Pulmonale
Acute Cystitis Acute Ethmoiditis
Acute Frontal Sinusitis Acute Kidney Failure
Acute Maxillary Sinusitis Agammaglobulinemia, X-Linked
Allergic Rhinitis Alzheimer Disease
Anthracosis Anxiety
Aortic Valve Disease 1 Asbestosis
Aspergillosis Asthma
Atrophic Gastritis Benign Essential Hypertension
Bronchiectasis Bronchopneumonia
Cardiac Arrest Cerebral Atherosclerosis
Cerebral Degeneration Cerebrovascular Disease
Chronic Ethmoiditis Chronic Frontal Sinusitis
Chronic Kidney Failure Chronic Laryngitis
Chronic Maxillary Sinusitis Chronic Myocardial Ischemia
Chronic Pulmonary Heart Disease Chronic Rhinitis
Common Cold Conjunctivitis
Conn's Syndrome Cystitis
Decubitus Ulcer Deficiency Anemia
Diabetic Polyneuropathy Diaphragm Disease
Duodenitis Dyskinesia of Esophagus
Dysthymic Disorder Encephalopathy
Esophageal Candidiasis Esophageal Disease
Esophagitis Familial Atrial Fibrillation

Graphical network of the top 20 diseases related to Bronchitis:



Diseases related to Bronchitis

Symptoms & Phenotypes for Bronchitis

Symptoms:

12
  • cough
  • shortness of breath
  • low fever
  • chest tightness

UMLS symptoms related to Bronchitis:


snoring, pruritus, fever, coughing, recurrent pharyngitis

MGI Mouse Phenotypes related to Bronchitis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.7 CCL11 CD40LG CD79A CFTR ELANE IL5
2 immune system MP:0005387 9.36 CCL11 CD40LG CD79A CFTR ELANE IL5

Drugs & Therapeutics for Bronchitis

PubMedHealth treatment related to Bronchitis: 59

Acute bronchitis gets better on its own without treatment. If you feel weak and ill, it’s best to take it easy for a few days. This also means not doing any sports or other strenuous physical activities. Hot tea or broth is usually considered to have a soothing effect. But there is no scientific proof that drinking a lot more fluids than usual helps, or doesn’t help.Acute bronchitis doesn’t need to be treated with medication. Drugs such as paracetamol (acetaminophen) or ibuprofen are sometimes a good idea, though, for the relief of cold symptoms such as fever and pain.There hasn’t been enough research on the effectiveness of cough medicines that are designed to make you cough less (cough suppressants) or make it easier to cough up phlegm (expectorants). Because coughing has the important function of getting rid of mucus and foreign objects, cough suppressants should only be used for a limited amount of time, and only for really unpleasant, dry coughs that disrupt your sleep. Herbal medicines might relieve coughs somewhat.Because the symptoms are usually caused by viruses, antibiotics don’t help much in the treatment of acute bronchitis. But they can have side effects and contribute to bacteria becoming resistant. So antibiotics aren’t recommended as a treatment for acute bronchitis.

FDA approved drugs:

(show all 6)
# Drug Name Active Ingredient(s) 17 Company Approval Date
1
Augmentin 17 AMOXICILLIN; CLAVULANATE POTASSIUM SmithKline Beecham February 1996
2
Avelox I.V. 17 MOXIFLOXACIN HYDROCHLORIDE Bayer November 2001
3
Biaxin XL 17 CLARITHROMYCIN Abbott Laboratories March 2000
4
Cedax 17 CEFTIBUTEN DIHYDRATE Schering-Plough December 1995
5
Ceftin 17 CEFUROXIME AXETIL GlaxoSmithKline September 1997
6
Tequin 17 Bristol-Myers Squibb December, 1999

Drugs for Bronchitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 345)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
2
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
3
Montelukast Approved Phase 4,Phase 3,Phase 2 158966-92-8 5281040
4
Bambuterol Approved, Investigational Phase 4 81732-65-2, 81732-46-9 54766
5
Etanercept Approved, Investigational Phase 4,Phase 1,Phase 2 185243-69-0
6
Terbutaline Approved Phase 4 23031-25-6 5403
7
Budesonide Approved Phase 4,Phase 2 51333-22-3 5281004 63006
8
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1 83905-01-5 53477736 447043 55185
9
Ofloxacin Approved Phase 4,Phase 3,Phase 2,Phase 1 82419-36-1 4583
10
Acetylcysteine Approved, Investigational Phase 4,Phase 2 616-91-1 12035
11
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
12
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 100986-85-4 149096
13
Bromhexine Approved Phase 4 3572-43-8
14 Racepinephrine Approved Phase 4,Phase 3,Phase 2 329-65-7
15
Zinc Approved, Investigational Phase 4,Phase 3 7440-66-6 32051 23994
16
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
17
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560
18
Losartan Approved Phase 4 114798-26-4 3961
19
Ephedrine Approved Phase 4,Phase 3,Phase 2 299-42-3 9294
20
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
21
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
22
Mechlorethamine Approved, Investigational Phase 4,Phase 2,Phase 3 51-75-2 4033
23
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
24
Clarithromycin Approved Phase 4,Phase 3 81103-11-9 84029
25
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
26
Sulfamethoxazole Approved Phase 4 723-46-6 5329
27
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
28
Moxifloxacin Approved, Investigational Phase 4,Phase 3 151096-09-2, 354812-41-2 152946
29
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
30
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2 90-82-4 7028
31
Telithromycin Approved Phase 4 191114-48-4 0 5462516
32
Aztreonam Approved Phase 4 78110-38-0 5742832 5362041
33
Cefuroxime Approved Phase 4,Phase 3 55268-75-2 5479529 5361202
34
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
35
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
36
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3 93-14-1 3516
37
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
38
Cefdinir Approved Phase 4 91832-40-5 6915944
39
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 1406-16-2
40
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2 67-97-0 10883523 5280795 6221
41
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2 50-14-6 5280793
42
leucovorin Approved, Nutraceutical Phase 4,Phase 1 58-05-9 143 6006
43
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
44
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 59-30-3 6037
45
BCG vaccine Investigational Phase 4
46 Andrographolide Investigational Phase 4 5508-58-7
47
Salmeterol xinafoate Phase 4,Phase 3 94749-08-3 56801
48 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1 1177-87-3
49 Analgesics Phase 4,Phase 2,Phase 3,Phase 1
50 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 595)

# Name Status NCT ID Phase Drugs
1 The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma Unknown status NCT02002754 Phase 4 Bambuterol Hydrochloride tablets
2 Therapeutic Effect of Different Treatment Course With Inhaled Corticosteroids in Eosinophilic Bronchitis Patients Unknown status NCT02002715 Phase 4 Inhaled budesonide
3 Efficacy and Safety of add-on Montelukast to Inhaled Budesonide in the Treatment of Nonasthmatic Eosinophilic Bronchitis Unknown status NCT01121016 Phase 4 Montelukast
4 Airway Clearance for Prevention of COPD Exacerbation Unknown status NCT00181207 Phase 4
5 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease Unknown status NCT01595750 Phase 4 Roflumilast 500;Placebo
6 Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype Unknown status NCT01431625 Phase 4
7 Use of Roflumilast to Prevent Exacerbations in Fibrotic Sarcoidosis Patients (REFS) Unknown status NCT01830959 Phase 4 Roflumilast;Placebo
8 Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography Unknown status NCT01361984 Phase 4 Nebulized arformoterol;Salmeterol
9 Small Airways Evaluation and Treatment Unknown status NCT02526758 Phase 4 beclomethasone;formoterol;budesonide
10 Optimizing Influenza Vaccination in Surgical Oncology Patients Unknown status NCT01698177 Phase 4
11 Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection Unknown status NCT02054182 Phase 4 Vitamin D
12 Home Oxygen Therapy in Bronchiolitis Unknown status NCT01216553 Phase 4
13 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4 Racemic adrenaline;Isotonic saline
14 Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis Completed NCT00656747 Phase 4 Avelox (Moxifloxacin, BAY12-8039);Amoxicillin clavulanic acid
15 Mucolytic Effectiveness of Tacholiquine ® in Chronic Bronchitis Completed NCT02515799 Phase 4 Tacholiquine
16 The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis Completed NCT03073798 Phase 4 Roflumilast;Placebo
17 Telithromycin: in the Treatment of Acute Exacerbation of Chronic Bronchitis in Adult Outpatients With COPD Completed NCT00538148 Phase 4 Telithromycin
18 PERSPECTIVE: Telithromycin - Acute Exacerbation of Chronic Bronchitis Completed NCT00132938 Phase 4 telithromycin
19 Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung Transplantation Completed NCT01109160 Phase 4 Azithromycin Dihydrate
20 Ceftidoren Versus Levofloxacin in the Treatment of Patients With Acute Exacerbations of Chronic Bronchitis (AECB) Completed NCT01467297 Phase 4 ceftidoren;levofloxacin
21 Ketek in CAP / AECB in Ambulatory Adult Patients Completed NCT00546676 Phase 4 Telithromycin
22 Efficacy Safety Study of Arformoterol/Tiotropium Combination Versus Either Therapy Alone in Chronic Obstructive Pulmonary Disease (COPD) Completed NCT00424528 Phase 4 Arformoterol Tartrate Inhalation Solution;Tiotropium;Arformoterol and Tiotropium;Placebo
23 Relative Potency of Inhaled Corticosteroids Completed NCT00292838 Phase 4 fluticasone 25, 50, 100, 200 mcg
24 Phase 4 Study - Mucinex D as Adjunct Therapy Completed NCT00441246 Phase 4 Mucinex D (600 mg guaifenesin and 60 mg pseudoephedrine HCl extended-release bi-layer tablets)
25 Effect of Addition Oral Montelukast to Standard Treatment in Acute Asthma in Hospitalized Preschool Children Completed NCT03369119 Phase 4 Montelukast 4 Mg Oral Granule;Placebos
26 Chronic Obstructive Pulmonary Disease (COPD) Post-hospitalization Study Completed NCT01110200 Phase 4 ADVAIR DISKUS 250/50 mg BID;SEREVENT 50 mcg BID
27 Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients Completed NCT00680056 Phase 4 Formoterol plus Placebo (Tiotropium);Formoterol plus Tiotropium
28 COPD on Primary Care Treatment (COOPT) Completed NCT00184977 Phase 4 N-acetylcysteine;fluticasone propionate
29 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
30 Inhaled Steroid Reduces Systemic Inflammation in COPD Completed NCT00175565 Phase 4 inhaled fluticasone 500 mcg b.i.d.
31 Clinical Trial for the Assessment of Delayed Antibiotic Treatment in Pediatric (DAP-Pediatrics) Completed NCT01800747 Phase 4
32 Roflumilast on Markers of Bone Metabolism and Endothelial Function in COPD Completed NCT01745848 Phase 4 Roflumilast
33 BENEFITS OF ACLIDINIUM BROMIDE IN THE RELIEF OF COPD SYMPTOMS INCLUDING COUGH Completed NCT02375724 Phase 4 Aclidinium Bromide;Placebo
34 Placebo Versus Antibiotics in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) Completed NCT00170222 Phase 4 doxycycline
35 Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders Completed NCT00132418 Phase 4 Enbrel;Placebo
36 Efficacy of Losartan in Preventing Progression of COPD Completed NCT00720226 Phase 4 Losartan;Placebo
37 Change of Inspiratory Peak Flow in COPD Completed NCT00561886 Phase 4 Formoterol
38 Advair HFA For Chronic Obstructive Pulmonary Disease(COPD) Completed NCT00633217 Phase 4 Fluticasone Propionate/Salmeterol DISKUS 250/50mcg;Fluticasone Propionate/Salmeterol Hydrofluoroalkane 134a MDI 230/42mcg
39 Telithromycin in Respiratory Tract Infections Completed NCT00261105 Phase 4 telithromycin
40 Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS) Completed NCT01329029 Phase 4 Roflumilast;Placebo
41 Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations Completed NCT01167452 Phase 4 Sulfamethoxazole/trimethoprim
42 Proteomic Profiling for Influenza Completed NCT00133588 Phase 4
43 Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies Completed NCT01363531 Phase 4
44 Effectiveness of Different Exercise Training Programs to the Profile of COPD Patients Completed NCT01336283 Phase 4
45 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
46 An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease Completed NCT00974805 Phase 4 Seretide 500 Accuhaler
47 Efficacy of Temporary Positive Expiratory Pressure (TPEP) in Chronic Hypersecretion Completed NCT00700388 Phase 4
48 Efficacy Safety Study of Arformoterol QD Dosing Versus BID Dosing in COPD Completed NCT00571428 Phase 4 Arformoterol Tartrate Inhalation Solution;Arformoterol Tartrate Inhalation Solution;Placebo
49 A 16-Week Study to Evaluate the Effect of Advair DISKUS™ 250/50mcg on Arterial Stiffness in Subjects With Chronic Obstructive Pulmonary Disease (COPD) Completed NCT00857766 Phase 4 ADVAIR DISKUS™ 250/50mcg
50 Study of the Effect of the ROX AC1 on Exercise Capacity and Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients Completed NCT00832611 Phase 4

Search NIH Clinical Center for Bronchitis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: bronchitis

Genetic Tests for Bronchitis

Genetic tests related to Bronchitis:

# Genetic test Affiliating Genes
1 Chronic Bronchitis 28

Anatomical Context for Bronchitis

MalaCards organs/tissues related to Bronchitis:

38
Lung, Testes, Skin, Heart, Bone, Tonsil, Bone Marrow

Publications for Bronchitis

Articles related to Bronchitis:

(show top 50) (show all 928)
# Title Authors Year
1
Assessment of Mycoplasma gallisepticum vaccine efficacy in a co-infection challenge model with QX-like infectious bronchitis virus. ( 29451010 )
2018
2
Recombinant live attenuated avian coronavirus vaccines with deletions in the accessory genes 3ab and/or 5ab protect against infectious bronchitis in chickens. ( 29366709 )
2018
3
Exposure to traffic-related air pollution and acute bronchitis in children: season and age as modifiers. ( 29440305 )
2018
4
Exposure to cooking oil fumes and chronic bronchitis in nonsmoking women aged 40A years and over: a health-care based study. ( 29439699 )
2018
5
Echocardiographic characteristics in Fontan patients before the onset of protein-losing enteropathy or plastic bronchitis. ( 29082544 )
2018
6
Innate antiviral immune response against infectious bronchitis virus and involvement of prostaglandin E2 in the uterine mucosa of laying hens. ( 29407895 )
2018
7
An underestimated cause of chronic cough: The Protracted Bacterial Bronchitis. ( 29387250 )
2018
8
Ambient Air Pollution and Chronic Bronchitis in a Cohort of U.S. Women. ( 29410384 )
2018
9
Detection of specific bacterial agents by quantitative PCR assays in the bronchoalveolar lavage fluid of dogs with eosinophilic bronchopneumopathy vs. dogs with chronic bronchitis and healthy dogs. ( 29428092 )
2018
10
Induction of innate host responses characterized by production of interleukin (IL)-1I^ and recruitment of macrophages to the respiratory tract of chickens following infection with infectious bronchitis virus (IBV). ( 29426399 )
2018
11
Mitochondrial bioenergy alterations in avian HD11 macrophages infected with infectious bronchitis virus. ( 29302792 )
2018
12
Induction of innate immune response following introduction of infectious bronchitis virus (IBV) in the trachea and renal tissues of chickens. ( 29330060 )
2018
13
Perception and Awareness of chronic obstructive pulmonary disease, Chronic Bronchitis and Pulmonary Emphysema in the Spanish Urban Population. ( 29428681 )
2018
14
Acute phase proteins and stress markers in the immediate response to a combined vaccination against Newcastle disease and infectious bronchitis viruses in specific pathogen free (SPF) layer chicks. ( 29182756 )
2018
15
Non-astmatic Eosinophilic Bronchitis. ( 29404185 )
2018
16
In with acute bronchitis; out with duodenal perforation: the potentially harmful cascade of over-testing. A case report. ( 29441163 )
2018
17
Clinical Outcome of Eosinophilic Airway Inflammation in Chronic Airway Diseases Including Nonasthmatic Eosinophilic Bronchitis. ( 29317659 )
2018
18
Phylogenetic analysis of avian infectious bronchitis virus isolates from Morocco: a retrospective study (1983 to 2014). ( 28421419 )
2017
19
Left upper lobe atelectasis due to plastic bronchitis. ( 29276877 )
2017
20
Cross-sectional evaluation of the Bronchitis Severity Score in Egyptian children: A move to reduce antibiotics. ( 28395688 )
2017
21
A Rare Case of Idiopathic Plastic Bronchitis. ( 29098106 )
2017
22
Fatal Progressive Membranous Obliterative Bronchitis: A Sequela of Influenza? ( 27984386 )
2017
23
Assessment of molecular and genetic evolution, antigenicity and virulence properties during the persistence of the infectious bronchitis virus in broiler breeders. ( 28895517 )
2017
24
Eosinophilic Bronchitis. ( 28854083 )
2017
25
ERS statement on protracted bacterial bronchitis in children. ( 28838975 )
2017
26
Use of aerosol inhalation treatment with budesonide and terbutaline sulfate on acute pediatric asthmatic bronchitis. ( 28810628 )
2017
27
Diagnostic accuracy of fractional exhaled nitric oxide in predicting cough variant asthma and eosinophilic bronchitis in adult patients with chronic cough: A systematic review and meta-analysis. ( 28088474 )
2017
28
Vaccination against infectious bronchitis virus: A continuous challenge. ( 28081857 )
2017
29
Complete genome sequences of two avian infectious bronchitis viruses isolated in Egypt: Evidence for genetic drift and genetic recombination in the circulating viruses. ( 28495648 )
2017
30
Metalworking fluids: a new cause of occupational non-asthmatic eosinophilic bronchitis. ( 28507075 )
2017
31
A lesson in plasticity: a 74-year-old man with plastic bronchitis. ( 28373346 )
2017
32
Plastic bronchitis: An unusual complication of acute chest syndrome in adult. ( 28443234 )
2017
33
Persistent Bacterial Bronchitis: Time to Venture beyond the Umbrella. ( 29322037 )
2017
34
Percutaneous thoracic duct intervention to treat plastic bronchitis related to Fontan palliation. ( 28869334 )
2017
35
The effect of diatomaceous earth in live, attenuated infectious bronchitis vaccine, immune responses, and protection against challenge. ( 28419351 )
2017
36
Bronchitis, Acute ( 28846312 )
2017
37
Network pharmacology-based identification of key pharmacological pathways of Yin-Huang-Qing-Fei capsule acting on chronic bronchitis. ( 28053519 )
2017
38
Genome characterization, antigenicity and pathogenicity of a novel infectious bronchitis virus type isolated from south China. ( 28800976 )
2017
39
Protracted bacterial bronchitis in children. ( 28828815 )
2017
40
Early investigational antibiotics for the treatment of acute exacerbations of chronic bronchitis. ( 28092467 )
2017
41
Airway Mucin Concentration as a Marker of Chronic Bronchitis. ( 28877023 )
2017
42
New real time and conventional RT-PCRs for updated molecular diagnosis of infectious bronchitis virus infection (IBV) in chickens in Egypt associated with frequent co-infections with avian influenza and Newcastle Disease viruses. ( 28336367 )
2017
43
Eotaxin and IL-4 levels are increased in induced sputum and correlate with sputum eosinophils in patients with nonasthmatic eosinophilic bronchitis. ( 28353595 )
2017
44
Different evolutionary trajectories of vaccine-controlled and non-controlled avian infectious bronchitis viruses in commercial poultry. ( 28472110 )
2017
45
Invasive Aspergillus Pseudomembranous and Obstructive Tracheo-bronchitis in an Immuno-competent Patient. ( 29322720 )
2017
46
Infectious Bronchitis Virus Variants: Molecular Analysis and Pathogenicity Investigation. ( 28937583 )
2017
47
Plastic bronchitis in a patient with silicosis. ( 28365186 )
2017
48
Infectious Bronchitis Virus Infection Induces Apoptosis during Replication in Chicken Macrophage HD11 Cells. ( 28933760 )
2017
49
Protection against infectious bronchitis virus by spike ectodomain subunit vaccine. ( 28899630 )
2017
50
The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain. ( 28081264 )
2017

Variations for Bronchitis

Expression for Bronchitis

Search GEO for disease gene expression data for Bronchitis.

Pathways for Bronchitis

Pathways related to Bronchitis according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.78 CCL11 CD40LG CD79A CXCL8 ELANE HSP90AB1
2
Show member pathways
12.44 CCL11 CD40LG CXCL8 HSP90AB1 IL5 RNASE3
3
Show member pathways
11.98 CCL11 CFTR CXCL8 TNF
4 11.77 CD79A IL5 MPO TNF
5
Show member pathways
11.77 CCL11 CFTR CXCL8 HSP90AB1 IL5 TNF
6 11.72 CXCL8 SERPINB1 TNF
7 11.69 CD40LG CXCL8 TNF
8 11.52 CD40LG IL5 TNF
9
Show member pathways
11.5 CD40LG CXCL8 IL5 TNF
10 11.49 CCL11 CD40LG IL5
11
Show member pathways
11.47 CD40LG CXCL8 TNF
12 11.34 CD40LG CXCL8 TNF
13 11.29 ELANE MPO TNF
14 10.89 CCL11 CD40LG CXCL8 IL5 TNF
15 10.85 CCL11 CD40LG CXCL8 IL5 TNF
16 10.82 CCL11 CXCL8 IL5 SERPINA1 TNF

GO Terms for Bronchitis

Cellular components related to Bronchitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.77 ALB CCL11 CD40LG CXCL8 ELANE IL5
2 extracellular region GO:0005576 9.5 ALB CCL11 CD40LG CXCL8 ELANE HSP90AB1
3 azurophil granule lumen GO:0035578 9.33 ELANE MPO RNASE3

Biological processes related to Bronchitis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.85 CCL11 CD40LG CXCL8 IL5 SLPI TNF
2 regulation of receptor activity GO:0010469 9.8 CCL11 CD40LG CXCL8 IL5 TNF VIP
3 response to lipopolysaccharide GO:0032496 9.76 ELANE MPO SLPI TAC1
4 defense response to bacterium GO:0042742 9.65 ELANE MPO RNASE3 SLPI TNF
5 inflammatory response GO:0006954 9.63 CCL11 CD40LG CXCL8 IL5 TAC1 TNF
6 positive regulation of protein localization to cell surface GO:2000010 9.52 HSP90AB1 TNF
7 positive regulation of podosome assembly GO:0071803 9.51 IL5 TNF
8 response to salt stress GO:0009651 9.49 HSP90AB1 TNF
9 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.48 ELANE TNF
10 regulation of immunoglobulin secretion GO:0051023 9.43 CD40LG TNF
11 response to yeast GO:0001878 9.4 ELANE MPO
12 neutrophil degranulation GO:0043312 9.17 ELANE HSP90AB1 MPO RNASE3 SERPINA1 SERPINB1
13 negative regulation of growth of symbiont in host GO:0044130 9.13 ELANE MPO TNF

Molecular functions related to Bronchitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase inhibitor activity GO:0004867 9.13 SERPINA1 SERPINB1 SLPI
2 cytokine activity GO:0005125 9.02 CCL11 CD40LG CXCL8 IL5 TNF

Sources for Bronchitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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