MCID: BRW006
MIFTS: 17

Brown Syndrome malady

Muscle diseases category

Summaries for Brown Syndrome

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Sources:
42NIH Rare Diseases, 63Wikipedia, 32MalaCards
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NIH Rare Diseases:42 Brown syndrome is an eye disorder characterized by abnormalities in the eye's ability to move. specifically, the ability to look up and in is affected by a problem in the superior oblique muscle/tendon. the condition may be present at birth (congenital) or it may develop following surgery or as a result of inflammation or a problem with development. some cases are constant while other are intermittent. treatment depends upon the cause and severity of the movement disorder. options include close observation, nonsteroidal anti-inflammatory agents like ibuprofen, corticosteroids, and surgery. last updated: 12/5/2011

MalaCards: Brown Syndrome, also known as tendon sheath adherence, superior oblique, is related to brown-sequard syndrome and brown's tendon sheath syndrome. An important gene associated with Brown Syndrome is PHOX2A (paired-like homeobox 2a). Affiliated tissues include eye, and related mouse phenotypes are behavior/neurological and respiratory system.

Wikipedia:63 Brown syndrome is a rare form of strabismus characterized by limited elevation of the affected eye. The... more...

Aliases & Classifications for Brown Syndrome

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42NIH Rare Diseases, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Muscle diseases


Aliases & Descriptions:

brown syndrome 42
tendon sheath adherence, superior oblique 42
superior oblique tendon sheath syndrome 42
brown tendon sheath syndrome 60


Related Diseases for Brown Syndrome

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of diseases related to Brown Syndrome:



Diseases related to brown syndrome

Clinical Features for Brown Syndrome

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Drugs & Therapeutics for Brown Syndrome

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Brown Syndrome

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Anatomical Context for Brown Syndrome

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Sources:
32MalaCards
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MalaCards organs/tissues related to Brown Syndrome:

32
Eye

Animal Models for Brown Syndrome or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Brown Syndrome:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053869.1FBN2, PHOX2A
2MP:00053888.8FBN2, PHOX2A

Publications for Brown Syndrome

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Genetic Variations for Brown Syndrome

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Expression for genes affiliated with Brown Syndrome

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Brown Syndrome

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Pathways for genes affiliated with Brown Syndrome

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Compounds for genes affiliated with Brown Syndrome

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GO Terms for genes affiliated with Brown Syndrome

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Products for genes affiliated with Brown Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Brown Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet