Summaries for Brown Syndrome

Sources:
30NIH Rare Diseases, 44Wikipedia, 22MalaCards
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NIH Rare Diseases: Brown syndrome is an eye disorder characterized by abnormalities in the eye's ability to move. Specifically, the ability to look up and in is affected by a problem in the superior oblique muscle/tendon. The condition may be present at birth (congenital) or it may develop following surgery or as a result of inflammation or a problem with development. Some cases are constant while other are intermittent. Treatment depends upon the cause and severity of the movement disorder. Options include close observation, nonsteroidal anti-inflammatory agents like Ibuprofen, corticosteroids, and surgery.30

MalaCards: Brown Syndrome, also known as tendon sheath adherence, superior oblique, is related to brown's tendon sheath syndrome and brown-sequard syndrome. An important gene associated with Brown Syndrome is PHOX2A (paired-like homeobox 2a). Related mouse phenotype respiratory system.

Wikipedia: Brown syndrome is a rare eye disorder characterized by defects and errors in eye movement. The disorder...44 more...

Aliases & Descriptions for Brown Syndrome

Sources:
30NIH Rare Diseases, 43UMLS
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brown syndrome 30
tendon sheath adherence, superior oblique 30
superior oblique tendon sheath syndrome 30
brown tendon sheath syndrome 43

Related Diseases for Brown Syndrome

Sources:
13GeneCards, 14GeneDecks
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Diseases related to brown syndrome by text searches and GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1brown's tendon sheath syndrome7.9
2brown-sequard syndrome7.9
3brooks wisniewski brown syndrome7.0
4spastic paraplegia facial cutaneous lesions6.5
5cramp-fasciculations syndrome5.5

Clinical Features for Brown Syndrome

Drugs & Therapeutics for Brown Syndrome

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Brown Syndrome

Anatomical Context for Brown Syndrome

Phenotypes for genes affiliated with Brown Syndrome

Sources:
25MGI
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MGI Mouse Phenotypes related to brown syndrome:

25
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1respiratory system phenotypeMP:00053889.1FBN2, PHOX2A

Publications for genes affiliated with Brown Syndrome

Sources:
35PubMed
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Articles related to brown syndrome:

idTitleAuthorsYearAffiliating Genes
1Congenital contractural arachnodactyly (Beals-Hecht syndrome) associated with Brown's syndrome (15912465)Fehlow P.2005FBN2
2Familial unilateral Brown syndrome. (12324876)Iannaccone A.... Engle E.C.2002PHOX2A

Expression for genes affiliated with Brown Syndrome

Sources:
1BioGPS
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Expression patterns in normal tissues for genes affiliated with Brown Syndrome

Pathways for genes affiliated with Brown Syndrome

Compounds for genes affiliated with Brown Syndrome

GO Terms for genes affiliated with Brown Syndrome

Sources for Brown Syndrome

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS